???global.info.a_carregar???
Identificação

Identificação pessoal

Nome completo
Patrícia Dias de Rijo
Data de nascimento
1973/06/20
Género
Feminino

Nomes de citação

  • Rijo, Patrícia

Identificadores de autor

Ciência ID
851A-88C2-0D45
ORCID iD
0000-0001-7992-8343

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1)
Francês Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2011/02/03
Concluído
Farmácia (Doutoramento)
Especialização em Especialidade: Química Farmacêutica e Terapêutica
Universidade de Lisboa, Portugal
"Phytochemical Study and Biological Activities of Diterpenes and Derivatives from Plectranthus Species" (TESE/DISSERTAÇÃO)
Aprovado com louvor e distinção
2011
Concluído
Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Phytochemical study and biological activities of diterpenes and derivatives from Plectranthus species" (TESE/DISSERTAÇÃO)
Distinção e Louvor
2003
Concluído
Química Farmacêutica (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Diterpenos de Plectranthus ornatus, derivados carbamoilados e actividade antimicrobiana" (TESE/DISSERTAÇÃO)
Muito Bom
1999
Concluído
Química (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Modificações Químicas em Diterpenos e Triterpenos" (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

2012 - Atual Investigador (Investigação)
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2012 - Atual Gestão de Ciência e Tecnologia
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2011 - 2013 Investigador (Investigação)
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Docência no Ensino Superior

2020/06/01 - Atual Professor Associado (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2011/06/01 - Atual Professor Auxiliar (Docente Universitário)
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2011/06/01 - Atual Professor Auxiliar (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012/02/02 - 2018/09/19 Professor Auxiliar (Docente Universitário)
Universidade Lusofona de Humanidades e Tecnologias Centro de Investigacao em Biociencias e Tecnologias da Saude, Portugal
2016 - 2018 Professor Auxiliar (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2015 - 2018 Professor Auxiliar (Docente Universitário)
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2016 - 2017 Professor Auxiliar (Docente Universitário)
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2015 - 2017 Professor Auxiliar (Docente Universitário)
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2011 - 2013 Professor Auxiliar (Docente Universitário)
Universidade de Lisboa Instituto de Investigacao do Medicamento, Portugal
2001/02/01 - 2011/05/31 Assistente (Docente Universitário)
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2001/02/01 - 2011/05/31 Assistente (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2009 - 2010 Assistente (Docente Universitário)
Universidade de Lisboa Instituto de Investigacao do Medicamento, Portugal
2001/09 - 2005/09 Monitor (Docente Universitário)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2002/09/01 - 2004/09/01 Assistente Convidado (Docente Universitário)
Escola Superior de Saude Ribeiro Sanches, Portugal
2002/09/01 - 2004/09/01 Assistente Convidado (Docente Universitário)
Escola Superior de Saúde de Ribeiro Sanches, Portugal

Outros

2011/02/09 - 2016/07/31 Professora Coordenadora sem Agregação
Escola Superior de Saude Ribeiro Sanches, Portugal
2011/02/09 - 2016/07/31 Professora Coordenadora sem Agregação
Escla Superior de Sáude de Ribeiro Sanches, Portugal
2005/05/05 - 2011/02/08 Professor coordenador convidado
Escola Superior de Saude Ribeiro Sanches, Portugal
2005/05/05 - 2011/02/08 Professor coordenador convidado
Escola Superior de Saúde de Ribeiro Sanches, Portugal
2007 - 2008 Colaboradora
Universidade de Lisboa Instituto de Investigacao do Medicamento, Portugal
2007 - 2007 Colaboradora
Universidade de Lisboa Instituto de Investigacao do Medicamento, Portugal
Projetos

Projeto

Designação Financiadores
2018 - 2021/06/29 Redes de coordenação de antibióticos como forma de potenciar a bioactividade dos fármacos
PTDC/QUI-OUT/30988/2017
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021 ANTIBIOTIC COORDINATION FRAMEWORKS AS A WAY TO ENHANCE THE BIOACTIVITY OF THE DRUGS - ACFS
PTDC/QUI-OUT/30988/2017
Investigador
2018 - 2019 NIPHARMIN: A NEW ANTIBACTERIAL SCAFFOLD AND BIOLOGICAL APPLICATIONS
NIPHARMIN
Investigador
JANE AND AATOS ERKKO FOUNDATION, Finlândia
2005 - 2009/06/30 OBTENÇÃO, IDENTIFICAÇÃO ESTRUTURAL E BIOACTIVIDADE DE METABOLITOS NATURAIS E QUIMICAMENTE MODIFICADOS OBTIDOS A PARTIR DE PLANTAS DA FAMÍLIA DAS LAMIACEAE
SFRH/BD/19250/2004
Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Produções

Publicações

Artigo em conferência
  1. J Marçalo; C Garcia; L Custódio; M Nicolai; C Reis; J Rodrigues Maria; A Romagnoli; et al. "Anti-inflammatory and anti-tubercular properties screening of natural products from Plectranthus species". 2017.
    10.1055/s-0037-1608136
  2. J Marçalo; C Garcia; M Nicolai; C Reis; C Faustino; M Rodrigues Luís; P Rijo. "Screening the dermatological potential of Plectranthus species components – antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase". 2017.
    10.1055/s-0037-1608568
Artigo em revista
  1. Joana M. Andrade; Eva María Domínguez-Martín; Marisa Nicolai; Célia Faustino; Luís Monteiro Rodrigues; Patrícia Rijo. "Screening the dermatological potential of plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase". Journal of Enzyme Inhibition and Medicinal Chemistry (2021): https://doi.org/10.1080/14756366.2020.1862099.
    10.1080/14756366.2020.1862099
  2. Ana Henriques Mota; Noélia Duarte; Ana Teresa Serra; António Ferreira; Maria Rosário Bronze; Luísa Custódio; Maria Manuela Gaspar; et al. "Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA and PCL-Based Nanoformulations". Pharmaceutics 12 12 (2020): 1181-1181. https://doi.org/10.3390/pharmaceutics12121181.
    10.3390/pharmaceutics12121181
  3. Paula Pereira; Carla Palma; Cíntia Ferreira-Pêgo; Olga Amaral; Anabela Amaral; Patrícia Rijo; João Gregório; Lídia Palma; Marisa Nicolai. "Grape Pomace: A Potential Ingredient for the Human Diet". Foods 9 12 (2020): 1772-1772. https://doi.org/10.3390/foods9121772.
    10.3390/foods9121772
  4. Ana Lúcia Morais; Patrícia Rijo; Belén Batanero; Marisa Nicolai. "Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases". Proceedings 60 1 (2020): 34-34. https://doi.org/10.3390/IECB2020-07090.
    10.3390/IECB2020-07090
  5. Catarina Garcia; Vera M. S. Isca; Filipe Pereira; Carlos M. Monteiro; Epole Ntungwe; Francisco Sousa; Jelena Dinic; et al. "Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors". Frontiers in Pharmacology 11 (2020): https://doi.org/10.3389%2Ffphar.2020.557789.
    10.3389/fphar.2020.557789
  6. Cíntia Almeida; Daniel Murta; Rui Nunes; André Rolim Baby; Patrícia Rijo; Catarina Rosado. "Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient". Biomedical and Biopharmaceutical Research Journal (2020): https://doi.org/10.19277/bbr.17.2.242.
    10.19277/bbr.17.2.242
  7. Vera M. S. Isca; Joana Andrade; Ana Sofia Fernandes; Paulo Paixão; Clara Uriel; Ana María Gómez; Noélia Duarte; Patrícia Rijo. "In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids". Molecules (2020): https://doi.org/10.3390/molecules25184250.
    10.3390/molecules25184250
  8. Ana Lúcia Morais; Patrícia Rijo; María Belén Batanero Hernán; Marisa Nicolai. "Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review". Biosensors 10 9 (2020): 121-121. https://doi.org/10.3390/bios10090121.
    10.3390/bios10090121
  9. Filipe Pereira; Teresa Figueiredo; Rodrigo F. M. de Almeida; Catarina A. C. Antunes; Catarina Garcia; Catarina P. Reis; Lia Ascensão; Rita G. Sobral; Patricia Rijo. "Unveiling the Mechanism of Action of 7a-acetoxy-6ß-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions". Biomolecules (2020): https://doi.org/10.3390/biom10070983.
    10.3390/biom10070983
  10. Cíntia Almeida; Patrícia Rijo; Catarina Rosado. "Bioactive Compounds from Hermetia Illucens Larvae as Natural Ingredients for Cosmetic Application". Biomolecules 10 7 (2020): 976-976. https://doi.org/10.3390/biom10070976.
    10.3390/biom10070976
  11. Tomasz Sliwinski; Przemyslaw Sitarek; Ewa Skala; Vera M. S. Isca; Ewelina Synowiec; Tomasz Kowalczyk; Michal Bijak; Patrícia Rijo. "Diterpenoids from Plectranthus spp. as Potential Chemotherapeutic Agents via Apoptosis". Pharmaceuticals 13 6 (2020): 123-123. https://doi.org/10.3390/ph13060123.
    10.3390/ph13060123
  12. Marisa Nicolai; Joana Mota; Ana S. Fernandes; Filipe Pereira; Paula Pereira; Catarina P. Reis; Maria Valéria Robles Velasco; et al. "Assessment of the Potential Skin Application of Plectranthus ecklonii Benth.". Pharmaceuticals 13 6 (2020): 120-120. https://doi.org/10.3390/ph13060120.
    10.3390/ph13060120
  13. Patrícia Rijo; Milica Pešic; Ana S. Fernandes; Cláudia N. Santos. "Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance". Oxidative Medicine and Cellular Longevity (2020): https://doi.org/10.1155/2020/2407074.
    10.1155/2020/2407074
  14. Eva María Domínguez-Martín; Joana Tavares; Patrícia Ríjo; Ana María Díaz-Lanza. "Zoopharmacology: A Way to Discover New Cancer Treatments". Biomolecules 10 6 (2020): 817-817. https://doi.org/10.3390/biom10060817.
    10.3390/biom10060817
  15. Vera M. S. Isca; Milan Sencanski; Nenad Filipovic; Daniel J. V. A. Dos Santos; Ana Cipak Gašparovic; Lucília Saraíva; Carlos A. M. Afonso; Patrícia Rijo; Alfonso T. García-Sosa. "Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21103671.
    10.3390/ijms21103671
  16. Paula C. Alves; Patrícia Rijo; Catarina Bravo; Alexandra M. M. Antunes; Vânia André. "Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes". Molecules 25 10 (2020): 2374-2374. https://doi.org/10.3390/molecules25102374.
    10.3390/molecules25102374
  17. Epole Ntungwe N; Eva M. Domínguez-Martín; Amilcar Roberto; Joana Tavares; Vera Isca; Paula Pereira; Maria-João Cebola; Patrícia Rijo. "Artemia species: An important tool to screen general toxicity samples". Current Pharmaceutical Design (2020): https://doi.org/10.2174/1381612826666200406083035.
    10.2174/1381612826666200406083035
  18. Vera M. S. Isca; Ricardo J. Ferreira; Catarina Garcia; Carlos M. Monteiro; Jelena Dinic; Suvi Holmstedt; Vânia André; et al. "Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors". ACS Medicinal Chemistry Letters (2020): https://doi.org/10.1021%2Facsmedchemlett.9b00642.
    10.1021/acsmedchemlett.9b00642
  19. Ana Henriques Mota; Joana Marçalo Andrade; Epole N Ntungwe; Paula Pereira; Maria João Cebola; Maria Gabriela Bernardo-Gil; Jesús Molpeceres; et al. "Green extraction of Sambucus nigra L. for potential application in skin nanocarriers". Green Materials (2020): 1-13. https://doi.org/10.1680/jgrma.18.00074.
    10.1680/jgrma.18.00074
  20. Nuno Saraiva; João G. Costa; Catarina Reis; Nuno Almeida; Patrícia Rijo; Ana Sofia Fernandes. "Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells". Biomolecules (2020): https://doi.org/10.3390/biom10010158.
    10.3390/biom10010158
  21. Ferreira, O.; Rijo, P.; Gomes, J.F.; Santos, R.; Monteiro, S.; Vilas-Boas, C.; Correia-Da-Silva, M.; et al. "Biofouling Inhibition with Grafted Econea Biocide: Toward a Nonreleasing Eco-Friendly Multiresistant Antifouling Coating". ACS Sustainable Chemistry and Engineering 8 1 (2020): 12-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077121349&partnerID=MN8TOARS.
    10.1021/acssuschemeng.9b04550
  22. Sitarek, P.; Toma, M.; Ntungwe, E.; Kowalczyk, T.; Skala, E.; Wieczfinska, J.; Sliwinski, T.; Rijo, P.. "Insight the biological activities of selected abietane diterpenes isolated from plectranthus spp.". Biomolecules 10 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078786645&partnerID=MN8TOARS.
    10.3390/biom10020194
  23. Almeida, C.; Murta, D.; Nunes, R.; Baby, A.R.; Rijo, P.; Rosado, C.. "Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient,Avaliação preliminar da actividade antimicrobiana de diferentes extractos de larvas de Hermetia illucens para aplicação como ingrediente cosmético". Biomedical and Biopharmaceutical Research 17 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85096891997&partnerID=MN8TOARS.
    10.19277/BBR.17.2.242
  24. Rijo, P.; Mori, M.. "Natural products as an important source in drug discovery". Current Pharmaceutical Design 26 24 (2020): 2805-2806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087890460&partnerID=MN8TOARS.
    10.2174/138161282624200625104355
  25. Murugesan, A.; Holmstedt, S.; Brown, K.C.; Koivuporras, A.; Macedo, A.S.; Nguyen, N.; Fonte, P.; et al. "Design and synthesis of novel quinic acid derivatives: In vitro cytotoxicity and anticancer effect on glioblastoma". Future Medicinal Chemistry 12 21 (2020): 1891-1910. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096151646&partnerID=MN8TOARS.
    10.4155/fmc-2020-0194
  26. Lepeltier, E.; Rijo, P.; Rizzolio, F.; Popovtzer, R.; Petrikaite, V.; Assaraf, Y.G.; Passirani, C.. "Nanomedicine to target multidrug resistant tumors". Drug Resistance Updates 52 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85085873870&partnerID=MN8TOARS.
    10.1016/j.drup.2020.100704
  27. Luís M. T. Frija; Epole Ntungwe; Przemyslaw Sitarek; Joana M. Andrade; Monika Toma; Tomasz Sliwinski; Lília Cabral; et al. "In Vitro Assessment of Antimicrobial, Antioxidant, and Cytotoxic Properties of Saccharin–Tetrazolyl and –Thiadiazolyl Derivatives: The Simple Dependence of the pH Value on Antimicrobial Activity". Pharmaceuticals 12 4 (2019): 167-167. https://doi.org/10.3390/ph12040167.
    10.3390/ph12040167
  28. Ana Santos-Rebelo; Pradeep Kumar; Viness Pillay; Yahya E. Choonara; Carla Eleutério; Mariana Figueira; Ana S. Viana; et al. "Development and Mechanistic Insight into the Enhanced Cytotoxic Potential of Parvifloron D Albumin Nanoparticles in EGFR-Overexpressing Pancreatic Cancer Cells". Cancers (2019): https://doi.org/10.3390/cancers11111733.
    10.3390/cancers11111733
  29. Tomasz Kowalczyk; Przemyslaw Sitarek; Ewa Skala; Patricia Rijo; Joana M. Andrade; Ewelina Synowiec; Janusz Szemraj; Urszula Krajewska; Tomasz Sliwinski. "An Evaluation of the DNA-Protective Effects of Extracts from Menyanthes trifoliata L. Plants Derived from In Vitro Culture Associated with Redox Balance and Other Biological Activities". Oxidative Medicine and Cellular Longevity (2019): https://doi.org/10.1155/2019/9165784.
    10.1155/2019/9165784
  30. Catarina Garcia; Epole Ntungwe; Ana Rebelo; Bessa, C.; Tijana Stankovic; Jelena Dinic; Díaz Lanza Ana M.; et al. "Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts". Biomolecules (2019): https://www.mdpi.com/2218-273X/9/10/616.
    10.3390/biom9100616
  31. Emília Alves; Patrícia Rijo; Luís Monteiro Rodrigues; Catarina Rosado. "Determination of relevant endpoints to evaluate the in vivo barrier function in cutaneous health". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.201.
    10.19277/BBR.16.1.201
  32. Marisa Nicolai; Nuno Almeida; Patricia Rijo; João Guilherme Costa; Nuno Saraiva; Ana Sofia Fernandes. "Cytotoxic effect of antioxidants found in food from plant origin on human osteosarcoma U2OS Cells". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.202.
    10.19277/BBR.16.1.202
  33. Diogo Matias; Marisa Nicolai; Lucília Saraiva; Rute Pinheiro; Célia Faustino; Ana Diaz Lanza; Catarina Pinto Reis; et al. "Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth". ACS Omega 4 5 (2019): 8094-8103. https://doi.org/10.1021%2Facsomega.9b00512.
    10.1021/acsomega.9b00512
  34. Diogo Matias; Marisa Nicolai; Ana Sofia Fernandes; Nuno Saraiva; Joana Almeida; Lucília Saraiva; Célia Faustino; et al. "Comparison Study of Different Extracts of Plectranthus madagascariensis, P. neochilus and the Rare P. porcatus (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities". Biomolecules (2019): https://www.mdpi.com/2218-273X/9/5/179.
    10.3390/biom9050179
  35. Vânia André; André Ramires Ferreira da Silva; Auguste Fernandes; Raquel Frade; Catarina Garcia; Patrícia Rijo; Alexandra M. M. Antunes; João Rocha; M. Teresa Duarte. "Mg- and Mn-MOFs Boost the Antibiotic Activity of Nalidixic Acid". ACS Applied Bio Materials (2019): https://doi.org/10.1021%2Facsabm.9b00046.
    10.1021/acsabm.9b00046
  36. Ribeiro, N; Galvão, AM; Gomes, CSB; Ramos, H; Pinheiro, R; Saraiva, L; Ntungwe, E; et al. "Naphthoylhydrazones: coordination to metal ions and biological screening". New Journal of Chemistry (2019):
    10.1039/c9nj01816f
  37. Alves, E; Rijo, P; Monteiro Rodrigues, L; Rosado, C. "Determination of relevant endpoints to evaluate the in vivo barrier function in cutaneous health". Journal Biomedical and Biopharmaceutical Research (2019):
    10.19277/bbr.16.1.201
  38. Nádia Ribeiro; Adelino M. Galvão; Clara S. B. Gomes; Helena Ramos; Rute Pinheiro; Lucília Saraiva; Epole Ntungwe; et al. "Naphthoylhydrazones: coordination to metal ions and biological screening". New Journal of Chemistry (2019): https://doi.org/10.1039/C9NJ01816F.
    10.1039/C9NJ01816F
  39. Sutradhar, M; Fernandes, AR; Paradinha, F; Rijo, P; Garcia, C; Roma Rodrigues, C; Pombeiro, AJL; Charmier, AJ. "A new Cu(II)-O-Carvacrotinate complex: Synthesis, characterization and biological activity". JOURNAL OF INORGANIC BIOCHEMISTRY (2019):
    10.1016/j.jinorgbio.2018.09.018
  40. Mota, AH; Direito, R; Carrasco, MP; Rijo, P; Ascensao, L; Viana, AS; Rocha, J; et al. "Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosupplementation in osteoarthritis". INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019):
    10.1016/j.ijpharm.2019.01.017
  41. Nicolai, M; Almeida, N; Rijo, P; Guilherme Costa, J; Saraiva, N; Fernandes, AS. "Cytotoxic effect of antioxidants found in food from plant origin on human osteosarcoma U2OS Cells". Journal Biomedical and Biopharmaceutical Research (2019):
    10.19277/bbr.16.1.202
  42. Filipa Siopa; Raquel F. M. Frade; Ana Diniz; Joana M. Andrade; Marisa Nicolai; Ana Meirinhos; Susana D. Lucas; et al. "Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies". ACS Omega (2018): https://doi.org/10.1021/acsomega.8b02347.
    10.1021/acsomega.8b02347
  43. Patricia Rijo; Vânia André. "Proceedings - CBiOS Science Sessions - 2018". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.15.2.190.
    10.19277/BBR.15.2.190
  44. Patrícia Rijo; Mariana Batista; Marisa Matos; Helga Rocha; Sandra Jesus; M. Fátima Simões. "Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.9.2.45.
    10.19277/BBR.9.2.45
  45. Marisa Nicolai; Paula Pereira; Patricia Rijo; Olga Amaral; Anabela Amaral; Lídia Palma. "Vitis vinera L. pomace: chemical and nutritional characterization". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.15.2.182.
    10.19277/BBR.15.2.182
  46. Tatu Rimpiläinen; Joana Andrade; Alexandra Nunes; Epole Ntungwe; Ana S. Fernandes; João R. Vale; João Rodrigues; et al. "Aminobenzylated 4-Nitrophenols as Antibacterial Agents Obtained from 5-Nitrosalicylaldehyde through a Petasis Borono–Mannich Reaction". ACS Omega (2018): https://doi.org/10.1021/acsomega.8b02381.
    10.1021/acsomega.8b02381
  47. L Roque; J Alopaeus; Claudia Reis; P Rijo; J Molpeceres; E Hagesaether; I Tho; Catarina Reis. "Mucoadhesive assessment of different antifungal nanoformulations". Bioinspiration & Biomimetics (2018): https://doi.org/10.1088/1748-3190/aad488.
    10.1088/1748-3190/aad488
  48. Joana M. Andrade; Alessandra Romagnoli; Joana F. Almeida; Inês M. Ferreira; Catarina Garcia; Ana Díaz-Lanza; Gian Maria Fimia; Patrícia Rijo. "Anti-mycobacterial activity of labdane and halimane diterpenes obtained from Plectranthus ornatus Codd". Journal Biomedical and Biopharmaceutical Research 15 1 (2018): 103-112. https://doi.org/10.19277/bbr.15.1.179.
    10.19277/bbr.15.1.179
  49. Joana M Andrade; Luísa Custódio; Alessandra Romagnoli; Catarina P Reis; Maria J Rodrigues; Catarina Garcia; Elisa Petruccioli; et al. "Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species". Future Medicinal Chemistry (2018): https://doi.org/10.4155%2Ffmc-2018-0043.
    10.4155/fmc-2018-0043
  50. A. Pereira Silva; M Ceu Costa; Patrícia Rijo; J.P. Gorjão-Clara; M. Bicho. "The teas of Portuguese centenarians". Free Radical Biology and Medicine 120 (2018): S163-S163. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.536.
    10.1016/j.freeradbiomed.2018.04.536
  51. João Costa; Nuno Saraiva; Patrícia Rijo; Nuno Almeida; Catarina Reis; Ana Sofia Fernandes. "Anti-tumor properties of the redox-active compound Parvifloron D in breast cancer cells". Free Radical Biology and Medicine 120 (2018): S119-S120. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.394.
    10.1016/j.freeradbiomed.2018.04.394
  52. Joana M. Andrade; Przemyslaw Sitarek; Ewa Skala; Ewelina Synowiec; Tomasz Kowalczyk; Ana Díaz-Lanza; Catarina Reis; Patrícia Rijo. "Mitochondrial dysfunction of halimane and labdane diterpenes in human lung cancer cells". Free Radical Biology and Medicine 120 (2018): S130-S130. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.429.
    10.1016/j.freeradbiomed.2018.04.429
  53. Catarina Garcia; Przemyslaw Sitarek; Ewa Skala; Ewelina Synowiec; Tomasz Sliwinski; Ana Diaz-Lanza; Catarina Reis; Patricia Rijo. "Diterpenes from Plectranthus spp.: a ROS-induced cytotoxicity study". Free Radical Biology and Medicine 120 (2018): S127-S127. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.419.
    10.1016/j.freeradbiomed.2018.04.419
  54. Joana M Andrade; Célia Faustino; Catarina Garcia; Diogo Ladeiras; Catarina P Reis; Patrícia Rijo. "Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity". Future Science OA 4 4 (2018): FSO283-FSO283. https://doi.org/10.4155%2Ffsoa-2017-0124.
    10.4155/fsoa-2017-0124
  55. Catarina A. B. Rodrigues; Iris Neto; Patricia Rijo; Carlos A. M. Afonso. "Synthesizing a Berberine Derivative and Evaluating Antimicrobial Activity To Reinforce with Students the Potential Significance of Small Chemical Structure Changes for Biological Systems". Journal of Chemical Education (2018): https://doi.org/10.1021/acs.jchemed.7b00458.
    10.1021/acs.jchemed.7b00458
  56. Cláudia Bessa; Joana Soares; Liliana Raimundo; Joana B. Loureiro; Célia Gomes; Flávio Reis; Miguel L. Soares; et al. "Discovery of a small-molecule protein kinase Cd-selective activator with promising application in colon cancer therapy". Cell Death & Disease 9 2 (2018): https://doi.org/10.1038%2Fs41419-017-0154-9.
    10.1038/s41419-017-0154-9
  57. Santos Rebelo, A; Garcia, C; Eleuterio, C; Bastos, A; Coelho, SC; Coelho, MAN; Molpeceres, J; et al. "Development of Parvifloron D-Loaded Smart Nanoparticles to Target Pancreatic Cancer". PHARMACEUTICS (2018):
    10.3390/pharmaceutics10040216
  58. Sitarek, P.; Kowalczyk, T.; Rijo, P.; Bialas, A.J.; Wielanek, M.; Wysokinska, H.; Garcia, C.; et al. "Over-Expression of AtPAP1 Transcriptional Factor Enhances Phenolic Acid Production in Transgenic Roots of Leonurus sibiricus L. and Their Biological Activities". Molecular Biotechnology 60 1 (2018): 74-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-85035797687&partnerID=MN8TOARS.
    10.1007/s12033-017-0048-1
  59. Rijo, P; André, V. "Proceedings - CBiOS Science Sessions - 2018". Journal Biomedical and Biopharmaceutical Research (2018):
    10.19277/bbr.15.2.190
  60. Nicolai, M; Pereira, P; Rijo, P; Amaral, O; Amaral, A; Palma, L. "Vitis vinera L. pomace: chemical and nutritional characterization". Journal Biomedical and Biopharmaceutical Research (2018):
    10.19277/bbr.15.2.182
  61. Rijo, P; Batista, M; Matos, M; Rocha, H; Jesus, S; Simões, MF. "Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts". Journal Biomedical and Biopharmaceutical Research (2018):
    10.19277/bbr.9.2.45
  62. Bernardes, C.E.S.; Garcia, C.; Pereira, F.; Mota, J.; Pereira, P.; Cebola, M.J.; Reis, C.P.; et al. "Extraction Optimization and Structural and Thermal Characterization of the Antimicrobial Abietane 7a-Acetoxy-6ß-hydroxyroyleanone". Molecular Pharmaceutics 15 4 (2018): 1412-1419. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044726740&partnerID=MN8TOARS.
    10.1021/acs.molpharmaceut.7b00892
  63. Garcia, C.; Silva, C.O.; Monteiro, C.M.; Nicolai, M.; Viana, A.; Andrade, J.M.; Barasoain, I.; et al. "Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction". Future Medicinal Chemistry 10 10 (2018): 1177-1189. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048107643&partnerID=MN8TOARS.
    10.4155/fmc-2017-0239
  64. Roque, L.; Castro, P.; Molpeceres, J.; Viana, A.S.; Roberto, A.; Reis, C.; Rijo, P.; Tho, I.; Sarmento, B.. "Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies". European Polymer Journal 104 (2018): 19-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-85046657641&partnerID=MN8TOARS.
    10.1016/j.eurpolymj.2018.04.032
  65. Roque, L; Duarte, N; Bronze, MR; Garcia, C; Alopaeus, J; Molpeceres, J; Hagesaether, E; et al. "Development of a bioadhesive nanoformulation with Glycyrrhiza glabra L. extract against Candida albicans". BIOFOULING (2018):
    10.1080/08927014.2018.1514391
  66. Nuno Almeida; Lara Ribeiro; João G. Costa; Patricia Rijo; M. Eduarda Araújo; Nuno Saraiva; Ana Sofia Fernandes. "Cytotoxicity of N-nitrosoguanidines in a breast cancer cell model". Journal Biomedical and Biopharmaceutical Research (2017): https://doi.org/10.19277/BBR.14.2.159.
    10.19277/BBR.14.2.159
  67. Elisabete R. Silva; Olga Ferreira; Patrícia Rijo; João C. Bordado; Maria J. Calhorda. "Antifouling Eco-Filters for Water Bio-Econtamination". Proceedings 2 6 (2017): 181-181. https://doi.org/10.3390/ecws-2-04950.
    10.3390/ecws-2-04950
  68. Mota, A.H.; Rijo, P.; Molpeceres, J.; Reis, C.P.. "Broad overview of engineering of functional nanosystems for skin delivery". International Journal of Pharmaceutics 532 2 (2017): 710-728. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027186861&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2017.07.078
  69. Almeida, N; Ribeiro, L; G. Costa, J; Rijo, P; Araújo, ME; Saraiva, N; Fernandes, AS. "Cytotoxicity of N-nitrosoguanidines in a breast cancer cell model". Journal Biomedical and Biopharmaceutical Research (2017):
    10.19277/bbr.14.2.159
  70. Reis, C.; Antunes, A.F.; Pereira, P.; Rijo, P.. "Nanosystems for skin delivery: From drugs to cosmetics". Current Drug Metabolism 18 5 (2017): 412-425. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021107182&partnerID=MN8TOARS.
    10.2174/1389200218666170306103101
  71. Roque, L.V.; Dias, I.S.; Cruz, N.; Rebelo, A.; Roberto, A.; Rijo, P.; Reis, C.P.. "Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia". Skin Pharmacology and Physiology 30 4 (2017): 197-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023775607&partnerID=MN8TOARS.
    10.1159/000475473
  72. Rebelo, A.; Molpeceres, J.; Rijo, P.; Reis, C.P.. "Pancreatic cancer therapy review: From classic therapeutic agents to modern nanotechnologies". Current Drug Metabolism 18 4 (2017): 346-359. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019714302&partnerID=MN8TOARS.
    10.2174/1389200218666170201151135
  73. Matias, D.; Rijo, P.; Reis, C.P.. "Phytosomes as biocompatible carriers of natural drugs". Current Medicinal Chemistry 24 6 (2017): 568-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017602832&partnerID=MN8TOARS.
    10.2174/0929867323666161028160855
  74. Mota, A.H.; Silva, C.O.; Nicolai, M.; Baby, A.; Palma, L.; Rijo, P.; Ascensão, L.; Reis, C.P.. "Design and evaluation of novel topical formulation with olive oil as natural functional active". Pharmaceutical Development and Technology (2017): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021845504&partnerID=MN8TOARS.
    10.1080/10837450.2017.1340951
  75. Roque, L.; Molpeceres, J.; Reis, C.; Rijo, P.; Reis, C.P.. "Past, recent progresses and future perspectives of nanotechnology applied to antifungal agents". Current Drug Metabolism 18 4 (2017): 280-290. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019724632&partnerID=MN8TOARS.
    10.2174/1389200218666170201152000
  76. De Almeida, T.S.; Júlio, A.; Mota, J.P.; Rijo, P.; Reis, C.P.. "An emerging integration between ionic liquids and nanotechnology: General uses and future prospects in drug delivery". Therapeutic Delivery 8 6 (2017): 461-473. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019838720&partnerID=MN8TOARS.
    10.4155/tde-2017-0002
  77. Scapin, E.; Frizzo, C.P.; Rodrigues, L.V.; Zimmer, G.C.; Vaucher, R.A.; Sagrillo, M.R.; Giongo, J.L.; et al. "Synthesis, antimicrobial activity and cytotoxic investigation of novel trifluoromethylated tetrazolo[1,5-a]pyrimidines". Medicinal Chemistry Research 26 3 (2017): 640-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009830284&partnerID=MN8TOARS.
    10.1007/s00044-017-1783-3
  78. Sitarek, P.; Rijo, P.; Garcia, C.; Skala, E.; Kalemba, D.; Bialas, A.J.; Szemraj, J.; et al. "Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. And Their Chemical Composition". Oxidative Medicine and Cellular Longevity 2017 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85011578898&partnerID=MN8TOARS.
    10.1155/2017/7384061
  79. Faustino, C.; Rijo, P.; Reis, C.P.. "Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease". Pharmacological Research 120 (2017): 68-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016254345&partnerID=MN8TOARS.
    10.1016/j.phrs.2017.03.020
  80. Alegre-Gómez, S.; Sainz, P.; Simões, M.F.; Rijo, P.; Moiteiro, C.; González-Coloma, A.; Martínez-Díaz, R.A.. "Antiparasitic Activity of Diterpenoids Against Trypanosoma cruzi". Planta Medica 83 3-4 (2017): 306-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986596253&partnerID=MN8TOARS.
    10.1055/s-0042-115646
  81. Ana Silva; João Moreira; Pedro Andrade; Marisa Nicolai; Patricia Rijo; Nelson Tavares. "Production of fermented Thai red glutinous rice using an isolated Monascus purpureus NART001 from commercially available Chinese red fermented rice". Journal Biomedical and Biopharmaceutical Research (2016): https://doi.org/10.19277/bbr.13.2.138.
    10.19277/bbr.13.2.138
  82. Francisco Caldeira; João Costa; Patricia Rijo; Nuno Saraiva; Ana Fernandes. "Xanthine Oxidase Inhibitory Activity of a Plectranthus saccatus aqueous extract". Journal Biomedical and Biopharmaceutical Research (2016): https://doi.org/10.19277/bbr.13.2.143.
    10.19277/bbr.13.2.143
  83. Clara Uriel; Patricia Rijo; Ana S. Fernandes; Ana M. Gómez; Bert Fraser-Reid; J. Cristóbal López. "Methyl 1,2-Orthoesters in Acid-Washed Molecular Sieves Mediated Glycosylations". ChemistrySelect 1 18 (2016): 6011-6015. http://dx.doi.org/10.1002/slct.201601613.
    10.1002/slct.201601613
  84. Filipa Siopa; Teresa Figueiredo; Raquel F. M. Frade; Iris Neto; Ana Meirinhos; Catarina P. Reis; Rita G. Sobral; Carlos A. M. Afonso; Patrícia Rijo. "Choline-Based Ionic Liquids: Improvement of Antimicrobial Activity". ChemistrySelect 1 18 (2016): 5909-5916. http://dx.doi.org/10.1002/slct.201600864.
    10.1002/slct.201600864
  85. Silva, C.O.; Rijo, P.; Molpeceres, J.; Ascensão, L.; Roberto, A.; Fernandes, A.S.; Gomes, R.; et al. "Bioproduction of gold nanoparticles for photothermal therapy". Therapeutic Delivery 7 5 (2016): 287-304. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964937758&partnerID=MN8TOARS.
    10.4155/tde-2015-0011
  86. Reis, C.P.; Roque, L.V.; Baptista, M.; Rijo, P.. "Innovative formulation of nystatin particulate systems in toothpaste for candidiasis treatment". Pharmaceutical Development and Technology 21 3 (2016): 282-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956508140&partnerID=MN8TOARS.
    10.3109/10837450.2014.999783
  87. Silva, C.O.; Petersen, S.B.; Reis, C.P.; Rijo, P.; Molpeceres, J.; Fernandes, A.S.; Gonçalves, O.; et al. "EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy". PLoS ONE 11 10 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992755798&partnerID=MN8TOARS.
    10.1371/journal.pone.0165419
  88. Serafim, C.; Ferreira, I.; Rijo, P.; Pinheiro, L.; Faustino, C.; Calado, A.; Garcia-Rio, L.. "Lipoamino acid-based micelles as promising delivery vehicles for monomeric amphotericin B". International Journal of Pharmaceutics 497 1-2 (2016): 23-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949665976&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.11.034
  89. Benites, J; Moiteiro, C; Figueiredo, AC; Rijo, P; Buc Calderon, P; Bravo, F; Gajardo, S; et al. "Chemical composition and antimicrobial activity of essential oil of peruvian Dalea strobilacea Barneby". BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS (2016):
  90. Hazra, S.; Meyrelles, R.; Charmier, A.J.; Rijo, P.; Guedes Da Silva, M.F.C.; Pombeiro, A.J.L.. "N-H¿O and N-H¿Cl supported 1D chains of heterobimetallic CuII/NiII-SnIVcocrystals". Dalton Transactions 45 44 (2016): 17929-17938. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994707444&partnerID=MN8TOARS.
    10.1039/c6dt03118h
  91. Benites, J.; Moiteiro, C.; Figueiredo, A.C.; Rijo, P.; Buc-Calderon, P.; Bravo, F.; Gajardo, S.; et al. "Chemical composition and antimicrobial activity of essential oil of Peruvian dalea strobilacea barneby,Composición química y actividad antimicrobiana del aceite esencial de la planta Peruana Dalea strobilaceae Barneby". Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 15 6 (2016): 429-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994709988&partnerID=MN8TOARS.
  92. Neto, Í.; Andrade, J.; Fernandes, A.S.; Pinto Reis, C.; Salunke, J.K.; Priimagi, A.; Candeias, N.R.; Rijo, P.. "Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies". ChemMedChem (2016): 2015-2023. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988448120&partnerID=MN8TOARS.
    10.1002/cmdc.201600244
  93. Nicolai, M.; Pereira, P.; Vitor, R.F.; Reis, C.P.; Roberto, A.; Rijo, P.. "Antioxidant activity and rosmarinic acid content of ultrasound-assisted ethanolic extracts of medicinal plants". Measurement: Journal of the International Measurement Confederation 89 (2016): 328-332. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964510703&partnerID=MN8TOARS.
    10.1016/j.measurement.2016.04.033
  94. Skaba, E.; Rijo, P.; Garcia, C.; Sitarek, P.; Kalemba, D.; Toma, M.; Szemraj, J.; et al. "The essential oils of rhaponticum carthamoides hairy roots and roots of soil-grown plants: Chemical composition and antimicrobial, anti-inflammatory, and antioxidant activities". Oxidative Medicine and Cellular Longevity 2016 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85008953562&partnerID=MN8TOARS.
    10.1155/2016/8505384
  95. Silva, C.O.; Molpeceres, J.; Batanero, B.; Fernandes, A.S.; Saraiva, N.; Costa, J.G.; Rijo, P.; et al. "Functionalized diterpene parvifloron D-loaded hybrid nanoparticles for targeted delivery in melanoma therapy". Therapeutic Delivery 7 8 (2016): 521-544. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979515564&partnerID=MN8TOARS.
    10.4155/tde-2016-0027
  96. Faustino, C.; Serafim, C.; Rijo, P.; Reis, C.P.. "Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents". Expert Opinion on Drug Delivery 13 8 (2016): 1133-1148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965070277&partnerID=MN8TOARS.
    10.1080/17425247.2016.1178233
  97. Ladeiras, D.; Monteiro, C.M.; Pereira, F.; Reis, C.P.; Afonso, C.A.M.; Rijo, P.. "Reactivity of diterpenoid quinones: Royleanones". Current Pharmaceutical Design 22 12 (2016): 1682-1714. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964285600&partnerID=MN8TOARS.
    10.2174/1381612822666151211094521
  98. Wagemaker, T.A.L.; Campos, P.M.B.G.M.; Fernandes, A.S.; Rijo, P.; Nicolai, M.; Roberto, A.; Rosado, C.; et al. "Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation". Drug Development and Industrial Pharmacy 42 10 (2016): 1695-1699. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965010204&partnerID=MN8TOARS.
    10.3109/03639045.2016.1165692
  99. Catarina Reis; Ana F. Antunes; Patricia Rijo; Marina Baptista; Joana P. Mota; Luis Monteiro Rodrigues. "A novel topical association with zinc oxide, chamomile and aloe vera extracts - stability and safety studies". Journal Biomedical and Biopharmaceutical Research 12 2 (2015): 251-264. https://doi.org/10.19277/bbr.12.2.122.
    10.19277/bbr.12.2.122
  100. Diogo Matias; Luis Roque; Maria de Fátima Simões; Ana Diaz-Lanza; Patrícia Rijo; Catarina P. Reis. "Plectranthus madagascariensis phytosomes: formulation optimization". Journal Biomedical and Biopharmaceutical Research 12 2 (2015): 223-231. https://doi.org/10.19277/BBR.12.2.119.
    10.19277/BBR.12.2.119
  101. D. Matias; M. Nicolai; J. Costa; N. Saraiva; A.S. Fernandes; M.F. Simões; A.M. Diaz-Lanza; C.P. Reis; P. Rijo. "Cytotoxicity screening of Plectranthus spp. extracts and individual components in MDA-MB-231 cells". Toxicology Letters 238 2 (2015): S240-S240. https://doi.org/10.1016%2Fj.toxlet.2015.08.707.
    10.1016/j.toxlet.2015.08.707
  102. Margarida Pereira; Diogo Matias; Filipe Pereira; Catarina P. Reis; M. Fátima Simões; Patricia Rijo. "Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts". Journal Biomedical and Biopharmaceutical Research (2015): https://doi.org/10.19277/BBR.12.1.111.
    10.19277/BBR.12.1.111
  103. Sara Rosa; V. Correia; I. Ribeiro; Patricia Rijo; F. Simões; N. Saraiva; A. Fernandes. "In vitro antioxidant properties of the diterpenes Parvifloron D and 7a-acetoxy-6ß- hydroxyroyleanone". Journal Biomedical and Biopharmaceutical Research (2015): https://doi.org/10.19277/BBR.12.1.104.
    10.19277/BBR.12.1.104
  104. Rosa, S; Correia, V; Ribeiro, I; Rijo, P; Simões, F; Saraiva, N; Fernandes, A. "In vitro antioxidant properties of the diterpenes Parvifloron D and 7a-acetoxy-6ß- hydroxyroyleanone". Journal Biomedical and Biopharmaceutical Research (2015):
    10.19277/bbr.12.1.104
  105. Pereira, M; Matias, D; Pereira, F; P. Reis, C; Simões, MF; Rijo, P. "Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts". Journal Biomedical and Biopharmaceutical Research (2015):
    10.19277/bbr.12.1.111
  106. Matias, D; Roque, L; Simões, MdF; Diaz-Lanza, A; Rijo, P; P. Reis, C. "Plectranthus madagascariensis phytosomes: formulation optimization". Journal Biomedical and Biopharmaceutical Research (2015):
    10.19277/bbr.12.2.119
  107. Silva, C.O.; Petersen, S.B.; Pinto Reis, C.; Rijo, P.; Molpeceres, J.; Vorum, H.; Neves-Petersen, M.T.. "Lysozyme photochemistry as a function of temperature. the protective effect of nanoparticles on lysozyme photostability". PLoS ONE 10 12 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84956630088&partnerID=MN8TOARS.
    10.1371/journal.pone.0144454
  108. Silva, C.O.; Rijo, P.; Molpeceres, J.; Figueiredo, I.V.; Ascensão, L.; Fernandes, A.S.; Roberto, A.; Reis, C.P.. "Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment". International Journal of Pharmaceutics 493 1-2 (2015): 271-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938828795&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.07.044
  109. Burmistrova, O.; Perdomo, J.; Simões, M.F.; Rijo, P.; Quintana, J.; Estévez, F.. "The abietane diterpenoid parvifloron D from Plectranthus ecklonii is a potent apoptotic inducer in human leukemia cells". Phytomedicine 22 11 (2015): 1009-1016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941565035&partnerID=MN8TOARS.
    10.1016/j.phymed.2015.06.013
  110. Gouveia, B.G.; Rijo, P.; Gonçalo, T.S.; Reis, C.P.. "Good manufacturing practices for medicinal products for human use". Journal of Pharmacy and Bioallied Sciences 7 2 (2015): 87-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927621792&partnerID=MN8TOARS.
    10.4103/0975-7406.154424
  111. Wagemaker, T.A.L.; Rijo, P.; Rodrigues, L.M.; Maia Campos, P.M.B.G.; Fernandes, A.S.; Rosado, C.. "Integrated approach in the assessment of skin compatibility of cosmetic formulations with green coffee oil". International Journal of Cosmetic Science 37 5 (2015): 506-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940953144&partnerID=MN8TOARS.
    10.1111/ics.12225
  112. Pereira, F.; Baptista, R.; Ladeiras, D.; Madureira, A.M.; Teixeira, G.; Rosado, C.; Fernandes, A.S.; et al. "Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders". Measurement: Journal of the International Measurement Confederation 74 (2015): 170-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938387201&partnerID=MN8TOARS.
    10.1016/j.measurement.2015.07.029
  113. Lukasz Czekanski; Tânia Santos de Almeida; Joana P. Mota; Patrícia Rijo; Maria Eduarda M. Araújo. "Synthesis of benzoazole ionic liquids and evaluation of their antimicrobial activity". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.2.94.
    10.19277/BBR.11.2.94
  114. D Matias; F Pereira; M Nicolai; A Roberto; N Saraiva; AS Fernandes; MF Simões; et al. "Abietane diterpenes from Plectranthus madagascariensis: A cytotoxicity screening". Planta Med 80 16 (2014): http://dx.doi.org/10.1055/s-0034-1394809.
    10.1055/s-0034-1394809
  115. D Matias; F Pereira; M Pereira; MF Simões; AM Diaz-Lanza; CP Reis; P Rijo. "Antimicrobial screening of Plectranthus madagascariensis Benth. extracts". Planta Med 80 16 (2014): http://dx.doi.org/10.1055/s-0034-1394759.
    10.1055/s-0034-1394759
  116. Maria João Cebola; Patricia Rijo. "Production of extracts from preserved olives using supercritical CO2 and preliminary evaluation of its polyphenol content". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.79.
    10.19277/BBR.11.1.79
  117. Patricia Rijo; Lara Ribeiro; Ana Sofia Fernandes; Célia Faustino. "A didactic approach for quantification of diazepam tablets by UV spectrophotometry". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.83.
    10.19277/BBR.11.1.83
  118. Carolina Correia; Patricia Rijo; Lia Ascensão; Marisa Nicolai; Diogo Matias; Catarina Pinto Reis. "Optimization of the encapsulation efficiency of a novel oral insulin delivery nanosystem". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.82.
    10.19277/BBR.11.1.82
  119. Matos, Ana C.; Gonçalves, Lídia M.; Rijo, Patrícia; Vaz, Mário A.; Almeida, António J.; Bettencourt, Ana F.. "A novel modified acrylic bone cement matrix. A step forward on antibiotic delivery against multiresistant bacteria responsible for prosthetic joint infections". Materials Science and Engineering: C 38 (2014): 218⿿226-218⿿226. http://dx.doi.org/10.1016/j.msec.2014.02.002.
    10.1016/j.msec.2014.02.002
  120. Cebola, MJ; Rijo, P. "Production of extracts from preserved olives using supercritical CO2 and preliminary evaluation of its polyphenol content". Journal Biomedical and Biopharmaceutical Research (2014):
    10.19277/bbr.11.1.79
  121. Czekanski, L; Santos de Almeida, T; P. Mota, J; Rijo, P; M. Araújo, ME. "Synthesis of benzoazole ionic liquids and evaluation of their antimicrobial activity". Journal Biomedical and Biopharmaceutical Research (2014):
    10.19277/bbr.11.2.94
  122. Rijo, P.; Matias, D.; Fernandes, A.S.; Simões, M.F.; Nicolai, M.; Reis, C.P.. "Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin". Polymers 6 2 (2014): 479-490. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899496961&partnerID=MN8TOARS.
    10.3390/polym6020479
  123. Rijo, P; Ribeiro, L; Fernandes, AS; Faustino, C. "A didactic approach for quantification of diazepam tablets by UV spectrophotometry". Journal Biomedical and Biopharmaceutical Research (2014):
    10.19277/bbr.11.1.83
  124. Correia, C; Rijo, P; Ascensão, L; Nicolai, M; Matias, D; Pinto Reis, C. "Optimization of the encapsulation efficiency of a novel oral insulin delivery nanosystem". Journal Biomedical and Biopharmaceutical Research (2014):
    10.19277/bbr.11.1.82
  125. Rijo, P.; Falé, P.L.; Serralheiro, M.L.; Simões, M.F.; Gomes, A.; Reis, C.. "Optimization of medicinal plant extraction methods and their encapsulation through extrusion technology". Measurement: Journal of the International Measurement Confederation 58 (2014): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907817461&partnerID=MN8TOARS.
    10.1016/j.measurement.2014.08.045
  126. Tais A. L. Wagemaker; Catarina Rosado; Jirrah P. Andrade; Ana Sofia Fernandes; Patricia Rijo; Patricia Maia Campos; Luis Monteiro Rodrigues. "Evaluation of the sensory properties of a cosmetic formulation containing green coffee oi". Journal Biomedical and Biopharmaceutical Research (2013): https://doi.org/10.19277/BBR.10.1.56.
    10.19277/BBR.10.1.56
  127. Rijo P; Duarte A; Francisco AP; Semedo-Lemsaddek T; Simões MF. "In vitro Antimicrobial Activity of Royleanone Derivatives Against Gram-Positive Bacterial Pathogens.". (2013): http://europepmc.org/abstract/med/23494919.
    10.1002/ptr.4961
  128. A. L. Wagemaker, T; Rosado, C; P. Andrade, J; Fernandes, AS; Rijo, P; Maia Campos, P; Monteiro Rodrigues, L. "Evaluation of the sensory properties of a cosmetic formulation containing green coffee oi". Journal Biomedical and Biopharmaceutical Research (2013):
    10.19277/bbr.10.1.56
  129. Wagemaker, Tais A.L.; Fernandes, Ana Sofia; Rosado, Catarina; Rijo, Patricia; Campos, Patricia Maia; Rodrigues, Luis M.. "Safety of green coffee oil in cosmetic formulations: From in vitro to clinical studies". Toxicology Letters 221 (2013): S231-S231. http://dx.doi.org/10.1016/j.toxlet.2013.05.561.
    10.1016/j.toxlet.2013.05.561
  130. Burmistrova, O.; Simões, M.F.; Rijo, P.; Quintana, J.; Bermejo, J.; Estévez, F.. "Antiproliferative activity of abietane diterpenoids against human tumor cells". Journal of Natural Products 76 8 (2013): 1413-1423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883155925&partnerID=MN8TOARS.
    10.1021/np400172k
  131. Reis, C.P.; Gomes, A.; Rijo, P.; Candeias, S.; Pinto, P.; Baptista, M.; Martinho, N.; Ascensão, L.. "Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles". Microscopy and Microanalysis 19 5 (2013): 1141-1150. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884546219&partnerID=MN8TOARS.
    10.1017/S1431927613000536
  132. Patrícia Rijo; Ana Sofia Fernandes; Fátima Simões; Lidia Pinheiro. "Evaluation of diterpenoids from P. ornatus as potential COX-1 inhibitors". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/bbr.9.1.33.
    10.19277/bbr.9.1.33
  133. Tais A. L. Wagemaker; Ana S. Fernandes; Patrícia Maia Campos; Luís Monteiro Rodrigues; Patrícia Rijo. "Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/BBR.9.2.43.
    10.19277/BBR.9.2.43
  134. L. Wagemaker, TA; Fernandes, AS; Maia Campos, P; Monteiro Rodrigues, L; Rijo, P. "Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations". Journal Biomedical and Biopharmaceutical Research (2012):
    10.19277/bbr.9.2.43
  135. Rijo, Patricia; Rodriguez, Benjamin; Duarte, Aida; Fatima Simoes, M.. "Antimicrobial Properties of Plectranthus ornatus Extracts, 11-acetoxyhalima-5, 13-dien-15-oic Acid Metabolite and its Derivatives". The Natural Products Journal 1 1 (2011): 57-64. http://dx.doi.org/10.2174/2210316311101010057.
    10.2174/2210316311101010057
  136. Rijo, P.; Simões, M.F.; Francisco, A.P.; Rojas, R.; Gilman, R.H.; Vaisberg, A.J.; Rodríguez, B.; Moiteiro, C.. "Antimycobacterial metabolites from Plectranthus: Royleanone derivatives against Mycobacterium tuberculosis strains". Chemistry and Biodiversity 7 4 (2010): 922-932. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951197862&partnerID=MN8TOARS.
    10.1002/cbdv.200900099
  137. Rijo, Patrícia. "Two new diterpenoids from Plectranthus species". (2010):
    10.1016/j.phytol.2010.08.002
  138. Rijo, Patrícia. "An easy and stereoselective rearrangement of an abietane diterpenoid into a bioactive microstegiol derivative". (2010):
    10.1016/j.phytol.2010.09.001
  139. Rijo, P.; Simões, M.F.; Duarte, A.; Rodríguez, B.. "Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity". Phytochemistry 70 9 (2009): 1161-1165. http://www.scopus.com/inward/record.url?eid=2-s2.0-68349136915&partnerID=MN8TOARS.
    10.1016/j.phytochem.2009.06.008
  140. Rijo, P; Esteves, M; Simões, MF; Silva, A; Duarte, A; Rodriguez, B. "Antimicrobial activity of 7a-acetoxy-6ß-hydroxyroyleanone 12-O-benzoyl esters". Planta Medica 74 09 (2008): http://dx.doi.org/10.1055/s-0028-1084426.
    10.1055/s-0028-1084426
  141. Rijo, P.; Gaspar-Marques, C.; Simões, M.F.; Jimeno, M.L.; Rodríguez, B.. "Further diterpenoids from Plectranthus ornatus and P. grandidentatus". Biochemical Systematics and Ecology 35 4 (2007): 215-221. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847273079&partnerID=MN8TOARS.
    10.1016/j.bse.2006.10.011
  142. Gaspar-Marques, C.; Rijo, P.; Simões, M.F.; Duarte, M.A.; Rodriguez, B.. "Abietanes from Plectranthus grandidentatus and P. hereroensis against methicillin- and vancomycin-resistant bacteria". Phytomedicine 13 4 (2006): 267-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-32844456848&partnerID=MN8TOARS.
    10.1016/j.phymed.2005.06.002
  143. Rijo, P.; Simões, M.F.; Rodríguez, B.. "Structural and spectral assignment of three forskolin-like diterpenoids isolated from Plectranthus ornatus". Magnetic Resonance in Chemistry 43 7 (2005): 595-598. http://www.scopus.com/inward/record.url?eid=2-s2.0-20544475432&partnerID=MN8TOARS.
    10.1002/mrc.1600
  144. Rijo, P.; Gaspar-Marques, C.; Simões, M.F.; Duarte, A.; Apreda-Rojas, M.D.C.; Cano, F.H.; Rodríguez, B.. "Neoclerodane and labdane diterpenoids from Plectranthus ornatus". Journal of Natural Products 65 10 (2002): 1387-1390. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773406&partnerID=MN8TOARS.
    10.1021/np020203w
Resumo em conferência
  1. Bessa, C; Pereira, C; Maciel, C; Goncalves, J; Rijo, P; Simoes, M; Saraiva, L. "A selective activator of protein kinase Cdelta identified using yeast". 2013.

Outros

Outra produção
  1. Patrícia Rijo. 2019. Abietane Diterpenoids from Plectranthus spp. as a potential new class of Protein Kinase C Modulators. https://doi.org/10.3390%2Fecmc2019-06405.
    10.3390/ecmc2019-06405
  2. Joana Tavares; Epole Ntungwe; Vera Isca; Eva Dominguez; Patrícia Rijo. 2019. Optimization extraction study for the isolation of a bioactive diterpene from Plectranthuns ornatus Codd.. https://doi.org/10.3390%2Fecmc2019-06446.
    10.3390/ecmc2019-06446
  3. Noélia Duarte; Cátia Ramalhete; Patrícia Rijo; Mariana Alves Reis; Maria-José U. Ferreira. 2019. Stilbenoids in Grapes and Wine. https://doi.org/10.1007%2F978-981-13-1745-3_21-1.
    10.1007/978-981-13-1745-3_21-1
  4. Epole Ngolle Ntungwe; Vera Isca; Joana Tavares; Máté Vágvölgyi; Roberto Amílcar; Lucilia Saraiva; Gabriella Spengler; Attila Hunyadi; Patrícia Rijo. 2019. Cytotoxic activity of coleon diterpenoids from Plectranthus mutabilis codd. https://doi.org/10.3390%2Fecmc2019-06323.
    10.3390/ecmc2019-06323
  5. Patricia Rijo; Vera Isca; Epole Ntungwe; Joana Tavares; Filipa Siopa; Joana Almeida; Lucilia Saraiva; et al. 2019. Design and molecular docking studies of new potential PKC-d activators based on royleanone scaffold. https://doi.org/10.3390%2Fecmc2019-06297.
    10.3390/ecmc2019-06297
  6. Miguel A. González-Cardenete; Alberto Yuste; Eva García-Martínez; Marisa Nicolai; Ramón Zaragozá; Patricia Rijo. 2019. Acetylcholinesterase and antioxidant evaluation of C18-functionalized ferruginol analogues. https://doi.org/10.3390%2Fecmc2019-06313.
    10.3390/ecmc2019-06313
  7. Eva María Domínguez Martín; Ana María Díaz Lanza; Patrícia Rijo; Célia Faustino. 2019. Anticancer Hybrid Combinations with phenolic compounds. https://doi.org/10.3390%2Fecmc2019-06319.
    10.3390/ecmc2019-06319
  8. VMS Isca; E Ntungwe; JF Almeida; IM Ferreira; R Pereira; F Siopa; J Almeida; et al. 2019. Molecular docking as a tool to design new royleanone derivatives for colon cancer therapy based on PKC-d modulation. https://doi.org/10.1055%2Fs-0039-3399909.
    10.1055/s-0039-3399909
  9. E Ntungwe; V Isca; M Vágvölgyie; G Spengler; A Hunyadi; P Rijo. 2019. Bio-guided phytochemical study of Plectranthus mutabilis Codd.. https://doi.org/10.1055%2Fs-0039-3399860.
    10.1055/s-0039-3399860
  10. Rijo, P. 2018. Cytotoxic Natural Products as an Approach Towards the Development of Therapeutic Agents for Precision Medicine.
    10.2174/138161282436190215142414
  11. Garcia, C; Teodosio, C; Oliveira, C; Diaz Lanza, A; Reis, C; Duarte, N; Rijo, P. 2018. Naturally Occurring Plectranthus-derived Diterpenes with Antitumoral Activities.
    10.2174/1381612825666190115144241
  12. Diogo Matias; Cláudia Bessa; M. Fátima Simões; Catarina P. Reis; Lucília Saraiva; Patrícia Rijo. 2016. Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy. http://dx.doi.org/10.1016/b978-0-444-63749-9.00002-5.
    10.1016/B978-0-444-63749-9.00002-5
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2019 - 2019 Preparação e análise de nanopartículas com produtos naturais
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2019 - 2019 Isolamento de um diterpeno bioactivo a partir de Plectranthus ornatus COOD
Orientador
Ciências Farmacêuticas (Mestrado)
2017 - 2017 Abietane Cationic Amphiphiles (ACA) - loaded polymeric microspheres to tackle resistant bacteria
Coorientador
Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2016 Unravelling new ethnopharmacological roles of Plectranthus species: biological activity screening
Orientador
Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Estudo e doseamento de compostos bioactivos do alecrim (Rosmarinus officinalis L.) e da salva (Salvia spp.)
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2015 - 2015 Compostos bioactivos e derivados do alecrim e da salva
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2015 - 2015 Estudo e separação de compostos bioactivos de espécies portuguesas de Lavanda
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2013 - 2013 A utilização etnobotânica do género Plectranthus
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2014 INDOLE ALKALOIDS AS LEADS FOR DEVELOPING EFFECTIVE ANTICANCER DRUGS TARGETING MULTIDRUG RESISTANT CANCER CELLS
Arguente principal
Angela Paterna (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
Distinções

Prémio

2018 Inclusiveness Target Countries (ITC) Conference Grants
European Cooperation in Science and Technology, Bélgica
2017 Best oral presentation
YRW Bionorica Award 2017; 11th Young Researchers Workshop of the 65th International Congress and the Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Alemanha
2017 Best Poster award and oral presentation
European Cooperation in Science and Technology, Bélgica
2016 Best Poster Award of medicinal plants and its products
2016 Best oral communication on experimental animals
SPCAL, Portugal
2016 Best oral communication with nanoformulations
24th International Conference on Bioencapsulation, Portugal
2016 Honorable mention for best oral presentation 6th International Congress of Aromatic and Medicinal Plants (CIPAM)
6th International Congress of Aromatic and Medicinal Plants (CIPAM), Portugal
2016 Best poster II Jornadas Científicas CBIOS
Grupo Lusófona, Portugal
2016 Best microscopy image
2013 Prémio Lusófona em Dermatocosmética
ALIES/SANINTER, Portugal

Outra distinção

2004 PhD grant SFRH/BD/19250/2004
Fundação para a Ciência e a Tecnologia, Portugal