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Patrícia Dias de Mendonça Rijo has graduated in Chemistry from the Faculty of Sciences at the University of Lisbon (FCUL), and Master and PhD degrees in Pharmaceutical and Therapeutic Chemistry from the Faculty of Pharmacy at the University of Lisbon (FFUL). Currently, she is an Associate Professor at the School of Sciences and Health Technologies (ECTS) at the Universidade Lusófona de Humanidades e Tecnologias (ULHT, Lisbon, Portugal) since June 2020, where she is responsible for the Coordination of several disciplines in related domains of Chemistry, namely, Medicinal Chemistry and Pharmacognosy. Moreover, she is a member of the Scientific Council of ECTS (ULHT). She has focused her research in the medicinal chemistry, phytochemistry, and pharmacognosy areas with particular emphasis on Natural Products Chemistry. She published more than ninety papers in international peer-reviewed journals and has over two hundred communications (oral and panel) presented at both national and international meetings and conferences. In addition, she has two international registered patents.
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Identificação

Identificação pessoal

Nome completo
Patrícia Rijo
Data de nascimento
1973/06/20
Género
Feminino

Nomes de citação

  • Rijo, Patrícia

Identificadores de autor

Ciência ID
851A-88C2-0D45
ORCID iD
0000-0001-7992-8343
Google Scholar ID
https://scholar.google.com/citations?user=9joKfHsAAAAJ&hl=en&authuser=1
Researcher Id
O-2657-2015
Scopus Author Id
8600601700

Endereços de correio eletrónico

  • patriciamrijo@gmail.com (Pessoal)

Websites

  • https://twitter.com/phytochemlab?lang=en (Rede social)
  • https://www.linkedin.com/in/patricia-rijo-2604b921/?originalSubdomain=pt (Rede social)
  • http://cbios.ulusofona.pt/directory-board/ (Académico)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Química Médica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1)
Francês Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2) Utilizador elementar (A2)
Português (Idioma materno)
Formação
Grau Classificação
2011
Concluído
 Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Phytochemical study and biological activities of diterpenes and derivatives from Plectranthus species" (TESE/DISSERTAÇÃO)
 Distinção e Louvor
2003
Concluído
 Química Farmacêutica (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Diterpenos de Plectranthus ornatus, derivados carbamoilados e actividade antimicrobiana" (TESE/DISSERTAÇÃO)
 Muito Bom
1999
Concluído
 Química (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Modificações Químicas em Diterpenos e Triterpenos" (TESE/DISSERTAÇÃO)
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2012 - Atual Investigador (Investigação) Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2012 - Atual Gestão de Ciência e Tecnologia Universidade Lusofona de Humanidades e Tecnologias, Portugal
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2004 - Atual Investigador (Investigação) Universidade de Lisboa Instituto de Investigacao do Medicamento, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/06/01 - Atual Professor Associado (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2011/06/01 - Atual Professor Auxiliar (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2011 - 2016 Professor Coordenador (Docente Ensino Superior Politécnico) Escola Superior de Saúde Ribeiro Sanches, Portugal
2002/09/01 - 2011/09/01 Assistente Convidado (Docente Universitário) Escola Superior de Saúde de Ribeiro Sanches, Portugal
2001/02/01 - 2011/05/31 Assistente (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2005/05/05 - 2011/02/08 Professor Adjunto Convidado (Docente Ensino Superior Politécnico) Escola Superior de Saúde de Ribeiro Sanches, Portugal
2001/09 - 2005/09 Monitor (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2014 - Atual Conselho científico Universidade Lusofona de Humanidades e Tecnologias, Portugal
2012 - Atual Coordenação ou direção de centro de investigação, departamento ou equivalente Grupo Lusófona, Portugal
2014 - 2016 Conselho científico/técnico-científico ou orgão correspondente Universidade Lusofona de Humanidades e Tecnologias, Portugal
2002 - 2016 Conselho científico/técnico-científico ou orgão correspondente Escola Superior de Saúde Ribeiro Sanches, Portugal
2002 - 2016 Conselho pedagógico Escola Superior de Saúde Ribeiro Sanches, Portugal
Projetos

Bolsa

Designação Financiadores
2022 - Atual Studies on the human Pgp folding
2021.09821.CPCA
 Fundação para a Ciência e a Tecnologia
2022 - 2023/06 Líquidos Iónicos Inteligentes para a valorização de resíduos alimentares
Provided by PTCRIS: EXPL/OCE-ETA/1109/2021
 Fundação para a Ciência e a Tecnologia
2021 - 2022/06 Novas Estratégias no Tratamento de Águas-Residuais – NETA
LISBOA-01-0247-FEDER-046959; POCI-01--0247-FEDER-046959
 European Regional Development Fund
2021 - 2022 Combining synergistic approaches to fight cancer
COFAC/ILIND/CBIOS/1/2021
 Instituto Lusófono de Investigação e Desenvolvimento
2018 - 2021/12 Redes de coordenação de antibióticos como forma de potenciar a bioactividade dos fármacos
Provided by PTCRIS: PTDC/QUI-OUT/30988/2017
 Fundação para a Ciência e a Tecnologia
2018 - 2019/12 Nipharmin: a new antibacterial scaffold and biological applications
Jane and Aatos Erkko Foundation
 Jane ja Aatos Erkon Säätiö
2005 - 2009/06 OBTENÇÃO, IDENTIFICAÇÃO ESTRUTURAL E BIOACTIVIDADE DE METABOLITOS NATURAIS E QUIMICAMENTE MODIFICADOS OBTIDOS A PARTIR DE PLANTAS DA FAMÍLIA DAS LAMIACEAE
Provided by PTCRIS: SFRH/BD/19250/2004
SFRH/BD/19250/2004
 Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2021 - 2023 Lusophone flora fighting disease: focus on therapeutic lysyl oxidase modulators (LusoModLOX)
ILIND/F+/EI/01/2020
Investigador
Em curso
2021 - 2022/06 Abietane Cationic Amphiphiles (ACA) to tackle resistant bacteria
COFAC/ILIND/CBIOS/1/2020
 ILIND-Instituto Lusófono de Investigação e Desenvolvimento
2021 - 2022/06 Exploiting the potential of dehydroabietic acid formulations to tackle skin ageing (DA4SAGE)
COFAC/ILIND/CBIOS/2/2020
Investigador
Em curso
2020 - 2021/06 Redox modulation of cancer progression
CBIOS/COFAC/FIPID/1/2019
Investigador
Concluído
Produções

Publicações

Artigo em conferência
  1. Silva, Alda Pereira da; Costa, M. Céu; Rijo, Patrícia; Gorjão Clara, João Pedro Pereira; Bicho, Manuel. "The teas of Portuguese centenarians". 2018.
    10.1016/j.freeradbiomed.2018.04.536
  2. J Marçalo; C Garcia; L Custódio; M Nicolai; C Reis; J Rodrigues Maria; A Romagnoli; et al. "Anti-inflammatory and anti-tubercular properties screening of natural products from Plectranthus species". 2017.
    10.1055/s-0037-1608136
  3. J Marçalo; C Garcia; M Nicolai; C Reis; C Faustino; M Rodrigues Luís; P Rijo. "Screening the dermatological potential of Plectranthus species components – antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase". 2017.
    10.1055/s-0037-1608568
Artigo em revista
  1. Ana Lucía Morocho-Jácome; Bruna Bertoloni dos Santos; João Carlos Monteiro de Carvalho; Tânia Santos de Almeida; Patrícia Rijo; Maria Valéria Robles Velasco; Catarina Rosado; André Rolim Baby. "Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of Neochloris oleoabundans". Cosmetics (2022): https://doi.org/10.3390/cosmetics9010009.
    10.3390/cosmetics9010009
  2. Patrícia Rijo; Lara Ribeiro; Marisa Nicolai; Paula Pereira; Célia Faustino. "Rapid UV-Vis spectroscopy methods for quantification of ranitidine tablets". Journal Biomedical and Biopharmaceutical Research (2021): https://doi.org/10.19277/bbr.18.2.271.
    10.19277/bbr.18.2.271
  3. Emília Alves; João Gregório; André Rolim Baby; Patrícia Rijo; Luis M. Rodrigues; Catarina Rosado. "Homemade Kefir Consumption Improves Skin Condition—A Study Conducted in Healthy and Atopic Volunteers". Foods 10 11 (2021): 2794-2794. https://doi.org/10.3390/foods10112794.
    10.3390/foods10112794
  4. Emilia Alves; Patricia Rijo; Luís Monteiro Rodrigues; Catarina Rosado. "Probiotics in the gut-skin axis – the case of kefir". Journal Biomedical and Biopharmaceutical Research (2021): https://doi.org/10.19277/bbr.18.2.261.
    10.19277/bbr.18.2.261
  5. Ana Ribeirinha Antão; Gabrielle Bangay; Eva María Domínguez-Martín; Ana María Díaz-Lanza; Patrícia Ríjo. "Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities". Frontiers in Pharmacology 12 (2021): https://doi.org/10.3389%2Ffphar.2021.768268.
    10.3389/fphar.2021.768268
  6. Epole Ntungwe; Eva María Domínguez-Martín; Gabrielle Bangay; Catarina Garcia; Iris Guerreiro; Eleonora Colombo; Lucília Saraiva; et al. "Self-Assembly Nanoparticles of Natural Bioactive Abietane Diterpenes". International Journal of Molecular Sciences (2021): https://www.mdpi.com/1422-0067/22/19/10210.
    10.3390/ijms221910210
  7. Iris Neto; Eva María Domínguez-Martín; Epole Ntungwe; Catarina P. Reis; Milica Pesic; Célia Faustino; Patrícia Rijo. "Dehydroabietic Acid Microencapsulation Potential as Biofilm-Mediated Infections Treatment". Pharmaceutics 13 6 (2021): 825-825. https://doi.org/10.3390/pharmaceutics13060825.
    10.3390/pharmaceutics13060825
  8. Epole Ntungwe; Vera M. S. Isca; Ana María Díaz-Lanza; Carlos A. M. Afonso; Patrícia Rijo. "General Toxicity screening of Royleanone derivatives using an Artemia salina model". Journal Biomedical and Biopharmaceutical Research (2021): https://doi.org/10.19277/bbr.18.1.254.
    10.19277/bbr.18.1.254
  9. Tomasz Kowalczyk; Anna Merecz-Sadowska; Patricia Rijo; Vera M. S. Isca; Laurent Picot; Marzena Wielanek; Tomasz Sliwinski; Przemyslaw Sitarek. "Preliminary Phytochemical Analysis and Evaluation of the Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation". Cells 10 5 (2021): 1242-1242. https://doi.org/10.3390/cells10051242.
    10.3390/cells10051242
  10. Ana Henriques Mota; Inês Prazeres; Henrique Mestre; Andreia Bento-Silva; Maria João Rodrigues; Noélia Duarte; Ana Teresa Serra; et al. "A Newfangled Collagenase Inhibitor Topical Formulation Based on Ethosomes with Sambucus nigra L. Extract". Pharmaceuticals 14 5 (2021): 467-467. https://doi.org/10.3390/ph14050467.
    10.3390/ph14050467
  11. Sérgio Faloni de Andrade; Patricia Rijo; Clemente Rocha; Lin Zhu; Luis Monteiro Rodrigues. "Characterizing the Mechanism of Action of Essential Oils on Skin Homeostasis—Data from Sonographic Imaging, Epidermal Water Dynamics, and Skin Biomechanics". Cosmetics (2021): https://doi.org/10.3390/cosmetics8020036.
    10.3390/cosmetics8020036
  12. Emília Alves; Epole Ntungwe; João Gregório; Monteiro Rodrigues L; Catarina Pereira Leite; Cristina Caleja; Eliana Pereira; et al. "Characterization of Kefir Produced in Household Conditions: Physicochemical and Nutritional Profile, and Storage Stability". Foods (2021): https://www.mdpi.com/2304-8158/10/5/1057.
    10.3390/foods10051057
  13. Epole Ntungwe; Eva María Domínguez-Martín; Catarina Teodósio; Silvia Teixidó-Trujillo; Natalia Armas Capote; Lucilia Saraiva; Ana María Díaz-Lanza; Noélia Duarte; Patrícia Rijo. "Preliminary Biological Activity Screening of Plectranthus spp. Extracts for the Search of Anticancer Lead Molecules". Pharmaceuticals (2021): https://doi.org/10.3390/ph14050402.
    10.3390/ph14050402
  14. Emília Alves; Patricia Rijo; Luis Monteiro Rodrigues; Catarina Rosado. "Acceptability of kefir produced by fermentation of Portuguese milk with CIDCA AGK1 grains in a sample of Portuguese consumers". Biomedical and Biopharmaceutical Research Journal 18 1 (2021): 1-9. https://doi.org/10.19277/bbr.18.1.252.
    10.19277/bbr.18.1.252
  15. "Antimicrobial Activity of Pyrazinamide Coordination Frameworks Synthesized by Mechanochemistry". Molecules 26 7 (2021): 1904-1904. http://dx.doi.org/10.3390/molecules26071904.
    10.3390/molecules26071904
  16. Olga Ferreira; Patrícia Rijo; João Gomes; Ricardo Santos; Sílvia Monteiro; Rita Guedes; Maria Luísa Serralheiro; et al. "Antimicrobial Ceramic Filters for Water Bio-Decontamination". Coatings 11 3 (2021): 323-323. https://doi.org/10.3390/coatings11030323.
    10.3390/coatings11030323
  17. Sandra Ferreira; Nuno Saraiva; Patrícia Rijo; Ana S. Fernandes. "LOXL2 Inhibitors and Breast Cancer Progression". Antioxidants (2021): https://doi.org/10.3390/antiox10020312.
    10.3390/antiox10020312
  18. Joana M. Andrade; Eva María Domínguez-Martín; Marisa Nicolai; Célia Faustino; Luís Monteiro Rodrigues; Patrícia Rijo. "Screening the dermatological potential of plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase". Journal of Enzyme Inhibition and Medicinal Chemistry (2021): https://doi.org/10.1080/14756366.2020.1862099.
    10.1080/14756366.2020.1862099
  19. Rijo, P.; Estévez, F.; Sitarek, P.; Ferreira, M.-J.U.. "Editorial: “Natural Products as a Tool to Design New anti-MDR Lead Molecules.”". Frontiers in Pharmacology 12 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85109141660&partnerID=MN8TOARS.
    10.3389/fphar.2021.694674
  20. Adouni, K.; Júlio, A.; Santos-Buelga, C.; González-Paramás, A.M.; Filipe, P.; Rijo, P.; Costa Lima, S.A.; et al. "Roots and rhizomes of wild Asparagus: Nutritional composition, bioactivity and nanoencapsulation of the most potent extract". Food Bioscience (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85118573618&partnerID=MN8TOARS.
    10.1016/j.fbio.2021.101334
  21. Leitão, E.P.T.; Ascenso, O.S.; Santos de Almeida, T.; González, I.; Hernández, I.; Quintana, J.; Estévez, F.; Rijo, P.. "Design and synthesis of naphthylchalcones as novel anti-leukaemia agents". Bioorganic Chemistry 117 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85117896060&partnerID=MN8TOARS.
    10.1016/j.bioorg.2021.105348
  22. Kowalczyk, T.; Sitarek, P.; Toma, M.; Rijo, P.; Domínguez-Martín, E.; Falcó, I.; Sánchez, G.; Sliwinski, T.. "Enhanced Accumulation of Betulinic Acid in Transgenic Hairy Roots of Senna obtusifolia Growing in the Sprinkle Bioreactor and Evaluation of Their Biological Properties in Various Biological Models". Chemistry and Biodiversity 18 8 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85110612708&partnerID=MN8TOARS.
    10.1002/cbdv.202100455
  23. Gomes, R.F.A.; Isca, V.M.S.; Andrade, K.; Rijo, P.; Afonso, C.A.M.. "Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents". ChemMedChem 16 18 (2021): 2781-2785. http://www.scopus.com/inward/record.url?eid=2-s2.0-85109266150&partnerID=MN8TOARS.
    10.1002/cmdc.202100369
  24. Erin, N.; Tavsan, E.; Akdeniz, Ö.; Isca, V.M.S.; Rijo, P.. "Rebound increases in chemokines by CXCR2 antagonist in breast cancer can be prevented by PKCd and PKCe activators". Cytokine 142 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85103292346&partnerID=MN8TOARS.
    10.1016/j.cyto.2021.155498
  25. Ana Henriques Mota; Noélia Duarte; Ana Teresa Serra; António Ferreira; Maria Rosário Bronze; Luísa Custódio; Maria Manuela Gaspar; et al. "Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA and PCL-Based Nanoformulations". Pharmaceutics 12 12 (2020): 1181-1181. https://doi.org/10.3390/pharmaceutics12121181.
    10.3390/pharmaceutics12121181
  26. Eva María Domínguez-Martín; Ana Margarida Antão; Epole Ntungwe; Vera M. S. Isca; Ana María Díaz-Lanza; Patrícia Rijo. "Phytochemical and Pharmacological Study of Plectranthus ecklonii Benth". Proceedings (2020): https://doi.org/10.3390/IECBM2020-08567.
    10.3390/IECBM2020-08567
  27. Paula Pereira; Carla Palma; Cíntia Ferreira-Pêgo; Olga Amaral; Anabela Amaral; Patrícia Rijo; João Gregório; Lídia Palma; Marisa Nicolai. "Grape Pomace: A Potential Ingredient for the Human Diet". Foods 9 12 (2020): 1772-1772. https://doi.org/10.3390/foods9121772.
    10.3390/foods9121772
  28. Ana Lúcia Morais; Patrícia Rijo; Belén Batanero; Marisa Nicolai. "Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases". Proceedings 60 1 (2020): 34-34. https://doi.org/10.3390/IECB2020-07090.
    10.3390/IECB2020-07090
  29. Catarina Garcia; Vera M. S. Isca; Filipe Pereira; Carlos M. Monteiro; Epole Ntungwe; Francisco Sousa; Jelena Dinic; et al. "Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors". Frontiers in Pharmacology 11 (2020): https://doi.org/10.3389%2Ffphar.2020.557789.
    10.3389/fphar.2020.557789
  30. Cíntia Almeida; Daniel Murta; Rui Nunes; André Rolim Baby; Patrícia Rijo; Catarina Rosado. "Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient". Biomedical and Biopharmaceutical Research Journal (2020): https://doi.org/10.19277/bbr.17.2.242.
    10.19277/bbr.17.2.242
  31. Vera M. S. Isca; Joana Andrade; Ana Sofia Fernandes; Paulo Paixão; Clara Uriel; Ana María Gómez; Noélia Duarte; Patrícia Rijo. "In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids". Molecules (2020): https://doi.org/10.3390/molecules25184250.
    10.3390/molecules25184250
  32. Ana Lúcia Morais; Patrícia Rijo; María Belén Batanero Hernán; Marisa Nicolai. "Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review". Biosensors 10 9 (2020): 121-121. https://doi.org/10.3390/bios10090121.
    10.3390/bios10090121
  33. Filipe Pereira; Teresa Figueiredo; Rodrigo F. M. de Almeida; Catarina A. C. Antunes; Catarina Garcia; Catarina P. Reis; Lia Ascensão; Rita G. Sobral; Patricia Rijo. "Unveiling the Mechanism of Action of 7a-acetoxy-6ß-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions". Biomolecules (2020): https://doi.org/10.3390/biom10070983.
    10.3390/biom10070983
  34. Cíntia Almeida; Patrícia Rijo; Catarina Rosado. "Bioactive Compounds from Hermetia Illucens Larvae as Natural Ingredients for Cosmetic Application". Biomolecules 10 7 (2020): 976-976. https://doi.org/10.3390/biom10070976.
    10.3390/biom10070976
  35. Tomasz Sliwinski; Przemyslaw Sitarek; Ewa Skala; Vera M. S. Isca; Ewelina Synowiec; Tomasz Kowalczyk; Michal Bijak; Patrícia Rijo. "Diterpenoids from Plectranthus spp. as Potential Chemotherapeutic Agents via Apoptosis". Pharmaceuticals 13 6 (2020): 123-123. https://doi.org/10.3390/ph13060123.
    10.3390/ph13060123
  36. Marisa Nicolai; Joana Mota; Ana S. Fernandes; Filipe Pereira; Paula Pereira; Catarina P. Reis; Maria Valéria Robles Velasco; et al. "Assessment of the Potential Skin Application of Plectranthus ecklonii Benth.". Pharmaceuticals 13 6 (2020): 120-120. https://doi.org/10.3390/ph13060120.
    10.3390/ph13060120
  37. Patrícia Rijo; Milica Pešic; Ana S. Fernandes; Cláudia N. Santos. "Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance". Oxidative Medicine and Cellular Longevity (2020): https://doi.org/10.1155/2020/2407074.
    10.1155/2020/2407074
  38. Eva María Domínguez-Martín; Joana Tavares; Patrícia Ríjo; Ana María Díaz-Lanza. "Zoopharmacology: A Way to Discover New Cancer Treatments". Biomolecules 10 6 (2020): 817-817. https://doi.org/10.3390/biom10060817.
    10.3390/biom10060817
  39. Vera M. S. Isca; Milan Sencanski; Nenad Filipovic; Daniel J. V. A. Dos Santos; Ana Cipak Gašparovic; Lucília Saraíva; Carlos A. M. Afonso; Patrícia Rijo; Alfonso T. García-Sosa. "Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21103671.
    10.3390/ijms21103671
  40. Paula C. Alves; Patrícia Rijo; Catarina Bravo; Alexandra M. M. Antunes; Vânia André. "Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes". Molecules 25 10 (2020): 2374-2374. https://doi.org/10.3390/molecules25102374.
    10.3390/molecules25102374
  41. Epole Ntungwe N; Eva M. Domínguez-Martín; Amilcar Roberto; Joana Tavares; Vera Isca; Paula Pereira; Maria-João Cebola; Patrícia Rijo. "Artemia species: An important tool to screen general toxicity samples". Current Pharmaceutical Design (2020): https://doi.org/10.2174/1381612826666200406083035.
    10.2174/1381612826666200406083035
  42. Vera M. S. Isca; Ricardo J. Ferreira; Catarina Garcia; Carlos M. Monteiro; Jelena Dinic; Suvi Holmstedt; Vânia André; et al. "Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors". ACS Medicinal Chemistry Letters (2020): https://doi.org/10.1021%2Facsmedchemlett.9b00642.
    10.1021/acsmedchemlett.9b00642
  43. Ana Henriques Mota; Joana Marçalo Andrade; Epole N Ntungwe; Paula Pereira; Maria João Cebola; Maria Gabriela Bernardo-Gil; Jesús Molpeceres; et al. "Green extraction of Sambucus nigra L. for potential application in skin nanocarriers". Green Materials (2020): 1-13. https://doi.org/10.1680/jgrma.18.00074.
    10.1680/jgrma.18.00074
  44. Nuno Saraiva; João G. Costa; Catarina Reis; Nuno Almeida; Patrícia Rijo; Ana Sofia Fernandes. "Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells". Biomolecules (2020): https://doi.org/10.3390/biom10010158.
    10.3390/biom10010158
  45. Ferreira, O.; Rijo, P.; Gomes, J.F.; Santos, R.; Monteiro, S.; Vilas-Boas, C.; Correia-Da-Silva, M.; et al. "Biofouling Inhibition with Grafted Econea Biocide: Toward a Nonreleasing Eco-Friendly Multiresistant Antifouling Coating". ACS Sustainable Chemistry and Engineering 8 1 (2020): 12-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077121349&partnerID=MN8TOARS.
    10.1021/acssuschemeng.9b04550
  46. Sitarek, P.; Toma, M.; Ntungwe, E.; Kowalczyk, T.; Skala, E.; Wieczfinska, J.; Sliwinski, T.; Rijo, P.. "Insight the biological activities of selected abietane diterpenes isolated from plectranthus spp.". Biomolecules 10 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078786645&partnerID=MN8TOARS.
    10.3390/biom10020194
  47. Almeida, C.; Murta, D.; Nunes, R.; Baby, A.R.; Rijo, P.; Rosado, C.. "Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient,Avaliação preliminar da actividade antimicrobiana de diferentes extractos de larvas de Hermetia illucens para aplicação como ingrediente cosmético". Biomedical and Biopharmaceutical Research 17 2 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85096891997&partnerID=MN8TOARS.
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  48. Rijo, P.; Mori, M.. "Natural products as an important source in drug discovery". Current Pharmaceutical Design 26 24 (2020): 2805-2806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087890460&partnerID=MN8TOARS.
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  49. Murugesan, A.; Holmstedt, S.; Brown, K.C.; Koivuporras, A.; Macedo, A.S.; Nguyen, N.; Fonte, P.; et al. "Design and synthesis of novel quinic acid derivatives: In vitro cytotoxicity and anticancer effect on glioblastoma". Future Medicinal Chemistry 12 21 (2020): 1891-1910. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096151646&partnerID=MN8TOARS.
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  50. Lepeltier, E.; Rijo, P.; Rizzolio, F.; Popovtzer, R.; Petrikaite, V.; Assaraf, Y.G.; Passirani, C.. "Nanomedicine to target multidrug resistant tumors". Drug Resistance Updates 52 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85085873870&partnerID=MN8TOARS.
    10.1016/j.drup.2020.100704
  51. Mota, Ana Henriques; Duarte, Noélia; Serra, Ana Teresa; Ferreira, António; Bronze, Maria Rosário; Custódio, Luísa; Gaspar, Maria Manuela; et al. "Further evidence of possible therapeutic uses of Sambucus nigra L. extracts by the assessment of the In Vitro and In Vivo anti-inflammatory properties of Its PLGA and PCL-Based Nanoformulations". (2020): http://hdl.handle.net/10400.1/14961.
    10.3390/pharmaceutics12121181
  52. Regina Ferreira, Olga; Rijo, Patrícia; Gomes, João; Santos, Ricardo; Monteiro, Silvia; Vilas-Boas, Cátia; Correia-da-Silva, Marta; et al. "Biofouling inhibition with grafted econea biocide: toward a nonreleasing eco-friendly multiresistant antifouling coating". (2020): http://hdl.handle.net/10400.21/11349.
  53. Fadipe, V.O.; Opoku, A.R.; Singh, M.; Pereira, A.R.; Rijo, P.; Mongalo, N.I.. "Antimycobacterial, antiplasmodial studies and cytotoxicity of oleanolic acid and its derivative from Syzygium aromaticum Linn (Myrtaceae),Estudos antiplasmódicos, antimicobacterianos e citotoxicidade do ácido oleanólico e do seu derivado da Syzygium aromaticum Linn (Myrtaceae)". Biomedical and Biopharmaceutical Research 17 2 (2020): 265-276. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105351686&partnerID=MN8TOARS.
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  54. Luís M. T. Frija; Epole Ntungwe; Przemyslaw Sitarek; Joana M. Andrade; Monika Toma; Tomasz Sliwinski; Lília Cabral; et al. "In Vitro Assessment of Antimicrobial, Antioxidant, and Cytotoxic Properties of Saccharin–Tetrazolyl and –Thiadiazolyl Derivatives: The Simple Dependence of the pH Value on Antimicrobial Activity". Pharmaceuticals 12 4 (2019): 167-167. https://doi.org/10.3390/ph12040167.
    10.3390/ph12040167
  55. Ana Santos-Rebelo; Pradeep Kumar; Viness Pillay; Yahya E. Choonara; Carla Eleutério; Mariana Figueira; Ana S. Viana; et al. "Development and Mechanistic Insight into the Enhanced Cytotoxic Potential of Parvifloron D Albumin Nanoparticles in EGFR-Overexpressing Pancreatic Cancer Cells". Cancers (2019): https://doi.org/10.3390/cancers11111733.
    10.3390/cancers11111733
  56. Tomasz Kowalczyk; Przemyslaw Sitarek; Ewa Skala; Patricia Rijo; Joana M. Andrade; Ewelina Synowiec; Janusz Szemraj; Urszula Krajewska; Tomasz Sliwinski. "An Evaluation of the DNA-Protective Effects of Extracts from Menyanthes trifoliata L. Plants Derived from In Vitro Culture Associated with Redox Balance and Other Biological Activities". Oxidative Medicine and Cellular Longevity (2019): https://doi.org/10.1155/2019/9165784.
    10.1155/2019/9165784
  57. Catarina Garcia; Epole Ntungwe; Ana Rebelo; Bessa, C.; Tijana Stankovic; Jelena Dinic; Díaz Lanza Ana M.; et al. "Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts". Biomolecules (2019): https://www.mdpi.com/2218-273X/9/10/616.
    10.3390/biom9100616
  58. Emília Alves; Patrícia Rijo; Luís Monteiro Rodrigues; Catarina Rosado; Alves, E; Rijo, P; Monteiro Rodrigues, L; Rosado, C. "Determination of relevant endpoints to evaluate the in vivo barrier function in cutaneous health". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.201.
    10.19277/BBR.16.1.201
  59. Marisa Nicolai; Nuno Almeida; Patricia Rijo; João Guilherme Costa; Nuno Saraiva; Ana Sofia Fernandes; Nicolai, M; et al. "Cytotoxic effect of antioxidants found in food from plant origin on human osteosarcoma U2OS Cells". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.202.
    10.19277/BBR.16.1.202
  60. Diogo Matias; Marisa Nicolai; Lucília Saraiva; Rute Pinheiro; Célia Faustino; Ana Diaz Lanza; Catarina Pinto Reis; et al. "Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth". ACS Omega 4 5 (2019): 8094-8103. https://doi.org/10.1021%2Facsomega.9b00512.
    10.1021/acsomega.9b00512
  61. Diogo Matias; Marisa Nicolai; Ana Sofia Fernandes; Nuno Saraiva; Joana Almeida; Lucília Saraiva; Célia Faustino; et al. "Comparison Study of Different Extracts of Plectranthus madagascariensis, P. neochilus and the Rare P. porcatus (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities". Biomolecules (2019): https://www.mdpi.com/2218-273X/9/5/179.
    10.3390/biom9050179
  62. Vânia André; André Ramires Ferreira da Silva; Auguste Fernandes; Raquel Frade; Catarina Garcia; Patrícia Rijo; Alexandra M. M. Antunes; João Rocha; M. Teresa Duarte. "Mg- and Mn-MOFs Boost the Antibiotic Activity of Nalidixic Acid". ACS Applied Bio Materials (2019): https://doi.org/10.1021%2Facsabm.9b00046.
    10.1021/acsabm.9b00046
  63. Nádia Ribeiro; Adelino M. Galvão; Clara S. B. Gomes; Helena Ramos; Rute Pinheiro; Lucília Saraiva; Epole Ntungwe; et al. "Naphthoylhydrazones: coordination to metal ions and biological screening". New Journal of Chemistry (2019): https://doi.org/10.1039/C9NJ01816F.
    10.1039/C9NJ01816F
  64. Sutradhar, M; Fernandes, AR; Paradinha, F; Rijo, P; Garcia, C; Roma Rodrigues, C; Pombeiro, AJL; Charmier, AJ. "A new Cu(II)-O-Carvacrotinate complex: Synthesis, characterization and biological activity". JOURNAL OF INORGANIC BIOCHEMISTRY (2019):
    10.1016/j.jinorgbio.2018.09.018
  65. Mota, AH; Direito, R; Carrasco, MP; Rijo, P; Ascensao, L; Viana, AS; Rocha, J; et al. "Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosupplementation in osteoarthritis". INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019): http://hdl.handle.net/10400.1/14389.
    10.1016/j.ijpharm.2019.01.017
  66. Frija, Luís M. T.; Ntungwe, Epole; Sitarek, Przemyslaw; Andrade, Joana M.; Toma, Monika; Sliwinski, Tomasz; Cabral, Lília; et al. "In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity". (2019): http://hdl.handle.net/10400.1/13551.
    10.3390/ph12040167
  67. Patricia Rijo; Vânia André; Rijo, P; André, V. "Proceedings - CBiOS Science Sessions - 2018". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.15.2.190.
    10.19277/BBR.15.2.190
  68. Patrícia Rijo; Mariana Batista; Marisa Matos; Helga Rocha; Sandra Jesus; M. Fátima Simões. "Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.9.2.45.
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  69. Tatu Rimpiläinen; Joana Andrade; Alexandra Nunes; Epole Ntungwe; Ana S. Fernandes; João R. Vale; João Rodrigues; et al. "Aminobenzylated 4-Nitrophenols as Antibacterial Agents Obtained from 5-Nitrosalicylaldehyde through a Petasis Borono–Mannich Reaction". ACS Omega (2018): https://doi.org/10.1021/acsomega.8b02381.
    10.1021/acsomega.8b02381
  70. L Roque; J Alopaeus; Claudia Reis; P Rijo; J Molpeceres; E Hagesaether; I Tho; Catarina Reis. "Mucoadhesive assessment of different antifungal nanoformulations". Bioinspiration & Biomimetics (2018): https://doi.org/10.1088/1748-3190/aad488.
    10.1088/1748-3190/aad488
  71. Joana M. Andrade; Alessandra Romagnoli; Joana F. Almeida; Inês M. Ferreira; Catarina Garcia; Ana Díaz-Lanza; Gian Maria Fimia; Patrícia Rijo. "Anti-mycobacterial activity of labdane and halimane diterpenes obtained from Plectranthus ornatus Codd". Journal Biomedical and Biopharmaceutical Research 15 1 (2018): 103-112. https://doi.org/10.19277/bbr.15.1.179.
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  72. Joana M Andrade; Luísa Custódio; Alessandra Romagnoli; Catarina P Reis; Maria J Rodrigues; Catarina Garcia; Elisa Petruccioli; et al. "Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species". Future Medicinal Chemistry (2018): https://doi.org/10.4155%2Ffmc-2018-0043.
    10.4155/fmc-2018-0043
  73. A. Pereira Silva; M Ceu Costa; Patrícia Rijo; J.P. Gorjão-Clara; M. Bicho. "The teas of Portuguese centenarians". Free Radical Biology and Medicine 120 (2018): S163-S163. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.536.
    10.1016/j.freeradbiomed.2018.04.536
  74. João Costa; Nuno Saraiva; Patrícia Rijo; Nuno Almeida; Catarina Reis; Ana Sofia Fernandes. "Anti-tumor properties of the redox-active compound Parvifloron D in breast cancer cells". Free Radical Biology and Medicine 120 (2018): S119-S120. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.394.
    10.1016/j.freeradbiomed.2018.04.394
  75. Joana M. Andrade; Przemyslaw Sitarek; Ewa Skala; Ewelina Synowiec; Tomasz Kowalczyk; Ana Díaz-Lanza; Catarina Reis; Patrícia Rijo. "Mitochondrial dysfunction of halimane and labdane diterpenes in human lung cancer cells". Free Radical Biology and Medicine 120 (2018): S130-S130. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.429.
    10.1016/j.freeradbiomed.2018.04.429
  76. Catarina Garcia; Przemyslaw Sitarek; Ewa Skala; Ewelina Synowiec; Tomasz Sliwinski; Ana Diaz-Lanza; Catarina Reis; Patricia Rijo. "Diterpenes from Plectranthus spp.: a ROS-induced cytotoxicity study". Free Radical Biology and Medicine 120 (2018): S127-S127. https://doi.org/10.1016%2Fj.freeradbiomed.2018.04.419.
    10.1016/j.freeradbiomed.2018.04.419
  77. Joana M Andrade; Célia Faustino; Catarina Garcia; Diogo Ladeiras; Catarina P Reis; Patrícia Rijo. "Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity". Future Science OA 4 4 (2018): FSO283-FSO283. https://doi.org/10.4155%2Ffsoa-2017-0124.
    10.4155/fsoa-2017-0124
  78. Catarina A. B. Rodrigues; Iris Neto; Patricia Rijo; Carlos A. M. Afonso. "Synthesizing a Berberine Derivative and Evaluating Antimicrobial Activity To Reinforce with Students the Potential Significance of Small Chemical Structure Changes for Biological Systems". Journal of Chemical Education (2018): https://doi.org/10.1021/acs.jchemed.7b00458.
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  79. Cláudia Bessa; Joana Soares; Liliana Raimundo; Joana B. Loureiro; Célia Gomes; Flávio Reis; Miguel L. Soares; et al. "Discovery of a small-molecule protein kinase Cd-selective activator with promising application in colon cancer therapy". Cell Death & Disease 9 2 (2018): https://doi.org/10.1038%2Fs41419-017-0154-9.
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  80. Santos Rebelo, A; Garcia, C; Eleuterio, C; Bastos, A; Coelho, SC; Coelho, MAN; Molpeceres, J; et al. "Development of Parvifloron D-Loaded Smart Nanoparticles to Target Pancreatic Cancer". PHARMACEUTICS (2018): https://hdl.handle.net/10216/117063.
    10.3390/pharmaceutics10040216
  81. Sitarek, P.; Kowalczyk, T.; Rijo, P.; Bialas, A.J.; Wielanek, M.; Wysokinska, H.; Garcia, C.; et al. "Over-Expression of AtPAP1 Transcriptional Factor Enhances Phenolic Acid Production in Transgenic Roots of Leonurus sibiricus L. and Their Biological Activities". Molecular Biotechnology 60 1 (2018): 74-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-85035797687&partnerID=MN8TOARS.
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  82. Nicolai, M; Pereira, P; Rijo, P; Amaral, O; Amaral, A; Palma, L; Marisa Nicolai; et al. "Vitis vinera L. pomace: chemical and nutritional characterization". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.15.2.182.
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  83. Rijo, P; Batista, M; Matos, M; Rocha, H; Jesus, S; Simões, MF. "Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts". Journal Biomedical and Biopharmaceutical Research (2018):
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  84. Bernardes, C.E.S.; Garcia, C.; Pereira, F.; Mota, J.; Pereira, P.; Cebola, M.J.; Reis, C.P.; et al. "Extraction Optimization and Structural and Thermal Characterization of the Antimicrobial Abietane 7a-Acetoxy-6ß-hydroxyroyleanone". Molecular Pharmaceutics 15 4 (2018): 1412-1419. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044726740&partnerID=MN8TOARS.
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  85. Garcia, C.; Silva, C.O.; Monteiro, C.M.; Nicolai, M.; Viana, A.; Andrade, J.M.; Barasoain, I.; et al. "Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction". Future Medicinal Chemistry 10 10 (2018): 1177-1189. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048107643&partnerID=MN8TOARS.
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  86. Roque, L; Duarte, N; Bronze, MR; Garcia, C; Alopaeus, J; Molpeceres, J; Hagesaether, E; et al. "Development of a bioadhesive nanoformulation with Glycyrrhiza glabra L. extract against Candida albicans". BIOFOULING (2018):
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  87. Siopa, Filipa; Frade, Raquel F. M.; Diniz, Ana; Andrade, Joana M.; Nicolai, Marisa; Meirinhos, Ana; Lucas, Susana D.; et al. "Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies". ACS Omega (2018): http://hdl.handle.net/10362/104680.
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  88. Roque, Luís; Castro, Pedro; Molpeceres, Jesus; Viana, Ana S.; Roberto, Amilcar; Reis, Claúdia; Rijo, Patrícia; et al. "Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies". European Polymer Journal 104 (2018): 19-31. http://hdl.handle.net/10400.14/25824.
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  89. Isabel Basto; William B. Stiles; Tiago Bento; Patricia Pinheiro; Inês Mendes; Daniel Rijo; João Salgado. "Fluctuation in the assimilation of problematic experiences: a case study of dynamic systems analysis". (2018): https://repositorio-aberto.up.pt/handle/10216/117544.
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  90. Basto, Isabel; Stiles, William B; Bento, Tiago; Pinheiro, Patrícia; Mendes, Inês; Rijo, Daniel; Salgado, João. "Fluctuation in the assimilation of problematic experiences: a case study of dynamic systems analysis". (2018): http://hdl.handle.net/1822/66070.
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  91. Nuno Almeida; Lara Ribeiro; João G. Costa; Patricia Rijo; M. Eduarda Araújo; Nuno Saraiva; Ana Sofia Fernandes; et al. "Cytotoxicity of N-nitrosoguanidines in a breast cancer cell model". Journal Biomedical and Biopharmaceutical Research (2017): https://doi.org/10.19277/BBR.14.2.159.
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  92. Elisabete R. Silva; Olga Ferreira; Patrícia Rijo; João C. Bordado; Maria J. Calhorda. "Antifouling Eco-Filters for Water Bio-Econtamination". Proceedings 2 6 (2017): 181-181. https://doi.org/10.3390/ecws-2-04950.
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  93. Mota, A.H.; Rijo, P.; Molpeceres, J.; Reis, C.P.. "Broad overview of engineering of functional nanosystems for skin delivery". International Journal of Pharmaceutics 532 2 (2017): 710-728. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027186861&partnerID=MN8TOARS.
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  94. Reis, C.; Antunes, A.F.; Pereira, P.; Rijo, P.. "Nanosystems for skin delivery: From drugs to cosmetics". Current Drug Metabolism 18 5 (2017): 412-425. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021107182&partnerID=MN8TOARS.
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  95. Roque, L.V.; Dias, I.S.; Cruz, N.; Rebelo, A.; Roberto, A.; Rijo, P.; Reis, C.P.. "Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia". Skin Pharmacology and Physiology 30 4 (2017): 197-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023775607&partnerID=MN8TOARS.
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  96. Rebelo, A.; Molpeceres, J.; Rijo, P.; Reis, C.P.. "Pancreatic cancer therapy review: From classic therapeutic agents to modern nanotechnologies". Current Drug Metabolism 18 4 (2017): 346-359. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019714302&partnerID=MN8TOARS.
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  97. Matias, D.; Rijo, P.; Reis, C.P.. "Phytosomes as biocompatible carriers of natural drugs". Current Medicinal Chemistry 24 6 (2017): 568-589. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017602832&partnerID=MN8TOARS.
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  98. Mota, A.H.; Silva, C.O.; Nicolai, M.; Baby, A.; Palma, L.; Rijo, P.; Ascensão, L.; Reis, C.P.. "Design and evaluation of novel topical formulation with olive oil as natural functional active". Pharmaceutical Development and Technology (2017): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021845504&partnerID=MN8TOARS.
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  99. Roque, L.; Molpeceres, J.; Reis, C.; Rijo, P.; Reis, C.P.. "Past, recent progresses and future perspectives of nanotechnology applied to antifungal agents". Current Drug Metabolism 18 4 (2017): 280-290. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019724632&partnerID=MN8TOARS.
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  100. De Almeida, T.S.; Júlio, A.; Mota, J.P.; Rijo, P.; Reis, C.P.. "An emerging integration between ionic liquids and nanotechnology: General uses and future prospects in drug delivery". Therapeutic Delivery 8 6 (2017): 461-473. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019838720&partnerID=MN8TOARS.
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  101. Scapin, E.; Frizzo, C.P.; Rodrigues, L.V.; Zimmer, G.C.; Vaucher, R.A.; Sagrillo, M.R.; Giongo, J.L.; et al. "Synthesis, antimicrobial activity and cytotoxic investigation of novel trifluoromethylated tetrazolo[1,5-a]pyrimidines". Medicinal Chemistry Research 26 3 (2017): 640-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009830284&partnerID=MN8TOARS.
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  102. Sitarek, P.; Rijo, P.; Garcia, C.; Skala, E.; Kalemba, D.; Bialas, A.J.; Szemraj, J.; et al. "Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. And Their Chemical Composition". Oxidative Medicine and Cellular Longevity 2017 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85011578898&partnerID=MN8TOARS.
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  103. Faustino, C.; Rijo, P.; Reis, C.P.. "Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease". Pharmacological Research 120 (2017): 68-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016254345&partnerID=MN8TOARS.
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  104. Alegre-Gómez, S.; Sainz, P.; Simões, M.F.; Rijo, P.; Moiteiro, C.; González-Coloma, A.; Martínez-Díaz, R.A.. "Antiparasitic Activity of Diterpenoids Against Trypanosoma cruzi". Planta Medica 83 3-4 (2017): 306-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84986596253&partnerID=MN8TOARS.
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  105. Isabel Basto; Patrícia Pinheiro; William B. Stiles; Daniel Rijo; João Salgado. "Changes in symptom intensity and emotion valence during the process of assimilation of a problematic experience: a quantitative study of a good outcome case of cognitive-behavioral therapy". (2017): https://repositorio-aberto.up.pt/handle/10216/107820.
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  106. Ana Silva; João Moreira; Pedro Andrade; Marisa Nicolai; Patricia Rijo; Nelson Tavares. "Production of fermented Thai red glutinous rice using an isolated Monascus purpureus NART001 from commercially available Chinese red fermented rice". Journal Biomedical and Biopharmaceutical Research (2016): https://doi.org/10.19277/bbr.13.2.138.
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  107. Francisco Caldeira; João Costa; Patricia Rijo; Nuno Saraiva; Ana Fernandes. "Xanthine Oxidase Inhibitory Activity of a Plectranthus saccatus aqueous extract". Journal Biomedical and Biopharmaceutical Research (2016): https://doi.org/10.19277/bbr.13.2.143.
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  108. Clara Uriel; Patricia Rijo; Ana S. Fernandes; Ana M. Gómez; Bert Fraser-Reid; J. Cristóbal López. "Methyl 1,2-Orthoesters in Acid-Washed Molecular Sieves Mediated Glycosylations". ChemistrySelect 1 18 (2016): 6011-6015. http://dx.doi.org/10.1002/slct.201601613.
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  109. Filipa Siopa; Teresa Figueiredo; Raquel F. M. Frade; Iris Neto; Ana Meirinhos; Catarina P. Reis; Rita G. Sobral; Carlos A. M. Afonso; Patrícia Rijo. "Choline-Based Ionic Liquids: Improvement of Antimicrobial Activity". ChemistrySelect 1 18 (2016): 5909-5916. http://dx.doi.org/10.1002/slct.201600864.
    10.1002/slct.201600864
  110. Silva, C.O.; Rijo, P.; Molpeceres, J.; Ascensão, L.; Roberto, A.; Fernandes, A.S.; Gomes, R.; et al. "Bioproduction of gold nanoparticles for photothermal therapy". Therapeutic Delivery 7 5 (2016): 287-304. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964937758&partnerID=MN8TOARS.
    10.4155/tde-2015-0011
  111. Reis, C.P.; Roque, L.V.; Baptista, M.; Rijo, P.. "Innovative formulation of nystatin particulate systems in toothpaste for candidiasis treatment". Pharmaceutical Development and Technology 21 3 (2016): 282-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956508140&partnerID=MN8TOARS.
    10.3109/10837450.2014.999783
  112. Serafim, C.; Ferreira, I.; Rijo, P.; Pinheiro, L.; Faustino, C.; Calado, A.; Garcia-Rio, L.. "Lipoamino acid-based micelles as promising delivery vehicles for monomeric amphotericin B". International Journal of Pharmaceutics 497 1-2 (2016): 23-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949665976&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.11.034
  113. Benites, J; Moiteiro, C; Figueiredo, AC; Rijo, P; Buc Calderon, P; Bravo, F; Gajardo, S; et al. "Chemical composition and antimicrobial activity of essential oil of peruvian Dalea strobilacea Barneby". BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS (2016):
  114. Hazra, S.; Meyrelles, R.; Charmier, A.J.; Rijo, P.; Guedes Da Silva, M.F.C.; Pombeiro, A.J.L.. "N-H¿O and N-H¿Cl supported 1D chains of heterobimetallic CuII/NiII-SnIVcocrystals". Dalton Transactions 45 44 (2016): 17929-17938. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994707444&partnerID=MN8TOARS.
    10.1039/c6dt03118h
  115. Benites, J.; Moiteiro, C.; Figueiredo, A.C.; Rijo, P.; Buc-Calderon, P.; Bravo, F.; Gajardo, S.; et al. "Chemical composition and antimicrobial activity of essential oil of Peruvian dalea strobilacea barneby,Composición química y actividad antimicrobiana del aceite esencial de la planta Peruana Dalea strobilaceae Barneby". Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 15 6 (2016): 429-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994709988&partnerID=MN8TOARS.
  116. Neto, Í.; Andrade, J.; Fernandes, A.S.; Pinto Reis, C.; Salunke, J.K.; Priimagi, A.; Candeias, N.R.; Rijo, P.. "Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies". ChemMedChem (2016): 2015-2023. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988448120&partnerID=MN8TOARS.
    10.1002/cmdc.201600244
  117. Nicolai, M.; Pereira, P.; Vitor, R.F.; Reis, C.P.; Roberto, A.; Rijo, P.. "Antioxidant activity and rosmarinic acid content of ultrasound-assisted ethanolic extracts of medicinal plants". Measurement: Journal of the International Measurement Confederation 89 (2016): 328-332. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964510703&partnerID=MN8TOARS.
    10.1016/j.measurement.2016.04.033
  118. Skaba, E.; Rijo, P.; Garcia, C.; Sitarek, P.; Kalemba, D.; Toma, M.; Szemraj, J.; et al. "The essential oils of rhaponticum carthamoides hairy roots and roots of soil-grown plants: Chemical composition and antimicrobial, anti-inflammatory, and antioxidant activities". Oxidative Medicine and Cellular Longevity 2016 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85008953562&partnerID=MN8TOARS.
    10.1155/2016/8505384
  119. Silva, C.O.; Molpeceres, J.; Batanero, B.; Fernandes, A.S.; Saraiva, N.; Costa, J.G.; Rijo, P.; et al. "Functionalized diterpene parvifloron D-loaded hybrid nanoparticles for targeted delivery in melanoma therapy". Therapeutic Delivery 7 8 (2016): 521-544. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979515564&partnerID=MN8TOARS.
    10.4155/tde-2016-0027
  120. Faustino, C.; Serafim, C.; Rijo, P.; Reis, C.P.. "Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents". Expert Opinion on Drug Delivery 13 8 (2016): 1133-1148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965070277&partnerID=MN8TOARS.
    10.1080/17425247.2016.1178233
  121. Ladeiras, D.; Monteiro, C.M.; Pereira, F.; Reis, C.P.; Afonso, C.A.M.; Rijo, P.. "Reactivity of diterpenoid quinones: Royleanones". Current Pharmaceutical Design 22 12 (2016): 1682-1714. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964285600&partnerID=MN8TOARS.
    10.2174/1381612822666151211094521
  122. Wagemaker, T.A.L.; Campos, P.M.B.G.M.; Fernandes, A.S.; Rijo, P.; Nicolai, M.; Roberto, A.; Rosado, C.; et al. "Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation". Drug Development and Industrial Pharmacy 42 10 (2016): 1695-1699. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965010204&partnerID=MN8TOARS.
    10.3109/03639045.2016.1165692
  123. Silva, Catarina Oliveira; Petersen, Steffen B.; Reis, Catarina Pinto; Rijo, Patricia; Molpeceres, Jesus; Fernandes, Ana Sofia; Gonçalves, Odete Sofia Lopes; et al. "EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy". PLoS ONE 11 10 (2016): http://hdl.handle.net/1822/51152.
    10.1371/journal.pone.0165419
  124. Basto, Isabel; Pinheiro, Patrícia; Stiles, William B.; Rijo, Daniel; Salgado, João. "Changes in symptom intensity and emotion valence during the process of assimilation of a problematic experience: A quantitative study of a good outcome case of cognitive-behavioral therapy". (2016): http://hdl.handle.net/10316/46643.
  125. Catarina Reis; Ana F. Antunes; Patricia Rijo; Marina Baptista; Joana P. Mota; Luis Monteiro Rodrigues. "A novel topical association with zinc oxide, chamomile and aloe vera extracts - stability and safety studies". Journal Biomedical and Biopharmaceutical Research 12 2 (2015): 251-264. https://doi.org/10.19277/bbr.12.2.122.
    10.19277/bbr.12.2.122
  126. D. Matias; M. Nicolai; J. Costa; N. Saraiva; A.S. Fernandes; M.F. Simões; A.M. Diaz-Lanza; C.P. Reis; P. Rijo. "Cytotoxicity screening of Plectranthus spp. extracts and individual components in MDA-MB-231 cells". Toxicology Letters 238 2 (2015): S240-S240. https://doi.org/10.1016%2Fj.toxlet.2015.08.707.
    10.1016/j.toxlet.2015.08.707
  127. Margarida Pereira; Diogo Matias; Filipe Pereira; Catarina P. Reis; M. Fátima Simões; Patricia Rijo. "Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts". Journal Biomedical and Biopharmaceutical Research (2015): https://doi.org/10.19277/BBR.12.1.111.
    10.19277/BBR.12.1.111
  128. Rosa, S; Correia, V; Ribeiro, I; Rijo, P; Simões, F; Saraiva, N; Fernandes, A; et al. "In vitro antioxidant properties of the diterpenes Parvifloron D and 7a-acetoxy-6ß- hydroxyroyleanone". Journal Biomedical and Biopharmaceutical Research (2015): https://doi.org/10.19277/BBR.12.1.104.
    10.19277/bbr.12.1.104
  129. Pereira, M; Matias, D; Pereira, F; P. Reis, C; Simões, MF; Rijo, P. "Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts". Journal Biomedical and Biopharmaceutical Research (2015):
    10.19277/bbr.12.1.111
  130. Matias, D; Roque, L; Simões, MdF; Diaz-Lanza, A; Rijo, P; P. Reis, C; Diogo Matias; et al. "Plectranthus madagascariensis phytosomes: formulation optimization". Journal Biomedical and Biopharmaceutical Research 12 2 (2015): 223-231. https://doi.org/10.19277/BBR.12.2.119.
    10.19277/bbr.12.2.119
  131. Silva, C.O.; Petersen, S.B.; Pinto Reis, C.; Rijo, P.; Molpeceres, J.; Vorum, H.; Neves-Petersen, M.T.. "Lysozyme photochemistry as a function of temperature. the protective effect of nanoparticles on lysozyme photostability". PLoS ONE 10 12 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84956630088&partnerID=MN8TOARS.
    10.1371/journal.pone.0144454
  132. Silva, C.O.; Rijo, P.; Molpeceres, J.; Figueiredo, I.V.; Ascensão, L.; Fernandes, A.S.; Roberto, A.; Reis, C.P.. "Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment". International Journal of Pharmaceutics 493 1-2 (2015): 271-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938828795&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.07.044
  133. Burmistrova, O.; Perdomo, J.; Simões, M.F.; Rijo, P.; Quintana, J.; Estévez, F.. "The abietane diterpenoid parvifloron D from Plectranthus ecklonii is a potent apoptotic inducer in human leukemia cells". Phytomedicine 22 11 (2015): 1009-1016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941565035&partnerID=MN8TOARS.
    10.1016/j.phymed.2015.06.013
  134. Gouveia, B.G.; Rijo, P.; Gonçalo, T.S.; Reis, C.P.. "Good manufacturing practices for medicinal products for human use". Journal of Pharmacy and Bioallied Sciences 7 2 (2015): 87-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927621792&partnerID=MN8TOARS.
    10.4103/0975-7406.154424
  135. Wagemaker, T.A.L.; Rijo, P.; Rodrigues, L.M.; Maia Campos, P.M.B.G.; Fernandes, A.S.; Rosado, C.. "Integrated approach in the assessment of skin compatibility of cosmetic formulations with green coffee oil". International Journal of Cosmetic Science 37 5 (2015): 506-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940953144&partnerID=MN8TOARS.
    10.1111/ics.12225
  136. Pereira, F.; Baptista, R.; Ladeiras, D.; Madureira, A.M.; Teixeira, G.; Rosado, C.; Fernandes, A.S.; et al. "Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders". Measurement: Journal of the International Measurement Confederation 74 (2015): 170-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938387201&partnerID=MN8TOARS.
    10.1016/j.measurement.2015.07.029
  137. Webster,Guilherme; Sens,Patrícia Maria; Salmito,Márcio Cavalcante; Cavalcante,José Diogo Rijo; Santos,Paula Regina Bonifácio dos; Silva,Ana Lívia Muniz da; Souza,Érica Carla Figueiredo de. "Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo". (2015): http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000400347.
  138. Lukasz Czekanski; Tânia Santos de Almeida; Joana P. Mota; Patrícia Rijo; Maria Eduarda M. Araújo; Czekanski, L; Santos de Almeida, T; et al. "Synthesis of benzoazole ionic liquids and evaluation of their antimicrobial activity". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.2.94.
    10.19277/BBR.11.2.94
  139. D Matias; F Pereira; M Nicolai; A Roberto; N Saraiva; AS Fernandes; MF Simões; et al. "Abietane diterpenes from Plectranthus madagascariensis: A cytotoxicity screening". Planta Med 80 16 (2014): http://dx.doi.org/10.1055/s-0034-1394809.
    10.1055/s-0034-1394809
  140. D Matias; F Pereira; M Pereira; MF Simões; AM Diaz-Lanza; CP Reis; P Rijo. "Antimicrobial screening of Plectranthus madagascariensis Benth. extracts". Planta Med 80 16 (2014): http://dx.doi.org/10.1055/s-0034-1394759.
    10.1055/s-0034-1394759
  141. Matos, Ana C.; Gonçalves, Lídia M.; Rijo, Patrícia; Vaz, Mário A.; Almeida, António J.; Bettencourt, Ana F.. "A novel modified acrylic bone cement matrix. A step forward on antibiotic delivery against multiresistant bacteria responsible for prosthetic joint infections". Materials Science and Engineering: C 38 (2014): 218⿿226-218⿿226. http://dx.doi.org/10.1016/j.msec.2014.02.002.
    10.1016/j.msec.2014.02.002
  142. Cebola, MJ; Rijo, P; Maria João Cebola; Patricia Rijo. "Production of extracts from preserved olives using supercritical CO2 and preliminary evaluation of its polyphenol content". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.79.
    10.19277/bbr.11.1.79
  143. Rijo, P.; Matias, D.; Fernandes, A.S.; Simões, M.F.; Nicolai, M.; Reis, C.P.. "Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin". Polymers 6 2 (2014): 479-490. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899496961&partnerID=MN8TOARS.
    10.3390/polym6020479
  144. Rijo, P; Ribeiro, L; Fernandes, AS; Faustino, C; Patricia Rijo; Lara Ribeiro; Ana Sofia Fernandes; Célia Faustino. "A didactic approach for quantification of diazepam tablets by UV spectrophotometry". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.83.
    10.19277/bbr.11.1.83
  145. Correia, C; Rijo, P; Ascensão, L; Nicolai, M; Matias, D; Pinto Reis, C; Carolina Correia; et al. "Optimization of the encapsulation efficiency of a novel oral insulin delivery nanosystem". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.82.
    10.19277/bbr.11.1.82
  146. Rijo, P.; Falé, P.L.; Serralheiro, M.L.; Simões, M.F.; Gomes, A.; Reis, C.. "Optimization of medicinal plant extraction methods and their encapsulation through extrusion technology". Measurement: Journal of the International Measurement Confederation 58 (2014): 249-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907817461&partnerID=MN8TOARS.
    10.1016/j.measurement.2014.08.045
  147. Tais A. L. Wagemaker; Catarina Rosado; Jirrah P. Andrade; Ana Sofia Fernandes; Patricia Rijo; Patricia Maia Campos; Luis Monteiro Rodrigues; et al. "Evaluation of the sensory properties of a cosmetic formulation containing green coffee oi". Journal Biomedical and Biopharmaceutical Research (2013): https://doi.org/10.19277/BBR.10.1.56.
    10.19277/BBR.10.1.56
  148. Rijo P; Duarte A; Francisco AP; Semedo-Lemsaddek T; Simões MF. "In vitro Antimicrobial Activity of Royleanone Derivatives Against Gram-Positive Bacterial Pathogens.". (2013): http://europepmc.org/abstract/med/23494919.
    10.1002/ptr.4961
  149. Wagemaker, Tais A.L.; Fernandes, Ana Sofia; Rosado, Catarina; Rijo, Patricia; Campos, Patricia Maia; Rodrigues, Luis M.. "Safety of green coffee oil in cosmetic formulations: From in vitro to clinical studies". Toxicology Letters 221 (2013): S231-S231. http://dx.doi.org/10.1016/j.toxlet.2013.05.561.
    10.1016/j.toxlet.2013.05.561
  150. Burmistrova, O.; Simões, M.F.; Rijo, P.; Quintana, J.; Bermejo, J.; Estévez, F.. "Antiproliferative activity of abietane diterpenoids against human tumor cells". Journal of Natural Products 76 8 (2013): 1413-1423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883155925&partnerID=MN8TOARS.
    10.1021/np400172k
  151. Reis, C.P.; Gomes, A.; Rijo, P.; Candeias, S.; Pinto, P.; Baptista, M.; Martinho, N.; Ascensão, L.. "Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles". Microscopy and Microanalysis 19 5 (2013): 1141-1150. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884546219&partnerID=MN8TOARS.
    10.1017/S1431927613000536
  152. Patrícia Rijo; Ana Sofia Fernandes; Fátima Simões; Lidia Pinheiro. "Evaluation of diterpenoids from P. ornatus as potential COX-1 inhibitors". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/bbr.9.1.33.
    10.19277/bbr.9.1.33
  153. Tais A. L. Wagemaker; Ana S. Fernandes; Patrícia Maia Campos; Luís Monteiro Rodrigues; Patrícia Rijo. "Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/BBR.9.2.43.
    10.19277/BBR.9.2.43
  154. L. Wagemaker, TA; Fernandes, AS; Maia Campos, P; Monteiro Rodrigues, L; Rijo, P. "Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations". Journal Biomedical and Biopharmaceutical Research (2012):
    10.19277/bbr.9.2.43
  155. Rijo, Patricia; Rodriguez, Benjamin; Duarte, Aida; Fatima Simoes, M.; Rijo, Patrícia; Rodríguez, Benjamín; Simões, Maria de Fátima. "Antimicrobial Properties of Plectranthus ornatus Extracts, 11-acetoxyhalima-5, 13-dien-15-oic Acid Metabolite and its Derivatives". The Natural Products Journal 1 1 (2011): 57-64. http://dx.doi.org/10.2174/2210316311101010057.
    10.2174/2210316311101010057
  156. Rijo, Patrícia. "Two new diterpenoids from Plectranthus species". (2010):
    10.1016/j.phytol.2010.08.002
  157. Simões, Maria de Fátima; Rijo, Patrícia; Duarte, Aida; Matias, Diogo; Rodríguez, Benjamín; Rijo, Patrícia. "An easy and stereoselective rearrangement of an abietane diterpenoid into a bioactive microstegiol derivative". (2010): http://dx.doi.org/10.1016/j.phytol.2010.09.001.
    http://dx.doi.org/10.1016/j.phytol.2010.09.001
  158. Simões, Maria de Fátima; Rijo, Patrícia; Duarte, Aida; Barbosa, Diana; Matias, Diogo; Delgado, Joana; Cirilo, Nádia; Rodríguez, Benjamín. "Two new diterpenoids from Plectranthus species". (2010): http://dx.doi.org/10.1016/j.phytol.2010.08.002.
    http://dx.doi.org/10.1016/j.phytol.2010.08.002
  159. Rijo, Patrícia; Simões, Maria de Fátima; Francisco, Ana Paula; Rojas, Rosário; Gilman, Robert H.; Vaisberg, Abraham J.; Rodríguez, Benjamín; et al. "Antimycobacterial metabolites from Plectranthus. Royleanone derivatives against Mycobacterium tuberculosis strains". Chemistry and Biodiversity 7 4 (2010): 922-932. http://dx.doi.org/10.1002/cbdv.200900099.
    http://dx.doi.org/10.1002/cbdv.200900099
  160. Rijo, P.; Simões, M.F.; Duarte, A.; Rodríguez, B.. "Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity". Phytochemistry 70 9 (2009): 1161-1165. http://www.scopus.com/inward/record.url?eid=2-s2.0-68349136915&partnerID=MN8TOARS.
    10.1016/j.phytochem.2009.06.008
  161. Rijo, Patricia; Simoes, Maria Fatima; Duarte, Aida; Rodriguez, Benjamin. "Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity". (2009): http://hdl.handle.net/10451/21355.
    http://dx.doi.org/10.1016/j.phytochem.2009.06.008
  162. Rijo, P; Esteves, M; Simões, MF; Silva, A; Duarte, A; Rodriguez, B. "Antimicrobial activity of 7a-acetoxy-6ß-hydroxyroyleanone 12-O-benzoyl esters". Planta Medica 74 09 (2008): http://dx.doi.org/10.1055/s-0028-1084426.
    10.1055/s-0028-1084426
  163. Rijo, P.; Gaspar-Marques, C.; Simões, M.F.; Jimeno, M.L.; Rodríguez, B.. "Further diterpenoids from Plectranthus ornatus and P. grandidentatus". Biochemical Systematics and Ecology 35 4 (2007): 215-221. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847273079&partnerID=MN8TOARS.
    10.1016/j.bse.2006.10.011
  164. Rijo, Patricia; Gaspar-Marques, Cristina; Simoes, Maria F.; Jimeno, Maria L.; Rodriguez, Benjamin. "Further diterpenoids from Plectranthus ornatus and P-grandidentatus". (2007): http://hdl.handle.net/10451/21134.
    http://dx.doi.org/10.1016/j.bse.2006.10.011
  165. Gaspar-Marques, C.; Rijo, P.; Simões, M.F.; Duarte, M.A.; Rodriguez, B.. "Abietanes from Plectranthus grandidentatus and P. hereroensis against methicillin- and vancomycin-resistant bacteria". Phytomedicine 13 4 (2006): 267-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-32844456848&partnerID=MN8TOARS.
    10.1016/j.phymed.2005.06.002
  166. Rijo, P.; Simões, M.F.; Rodríguez, B.. "Structural and spectral assignment of three forskolin-like diterpenoids isolated from Plectranthus ornatus". Magnetic Resonance in Chemistry 43 7 (2005): 595-598. http://www.scopus.com/inward/record.url?eid=2-s2.0-20544475432&partnerID=MN8TOARS.
    10.1002/mrc.1600
  167. Rijo, P.; Gaspar-Marques, C.; Simões, M.F.; Duarte, A.; Apreda-Rojas, M.D.C.; Cano, F.H.; Rodríguez, B.. "Neoclerodane and labdane diterpenoids from Plectranthus ornatus". Journal of Natural Products 65 10 (2002): 1387-1390. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773406&partnerID=MN8TOARS.
    10.1021/np020203w
  168. Rijo, Patricia; Simões, MFátima; Araújo, MEduarda; Duarte, Aida. "Antimicrobial activity of the diterpene 7 a-acetoxy-6b-hidroxyroyleanone and its 6b-carbamoyl derivative". (2002): http://hdl.handle.net/10451/22078.
Capítulo de livro
  1. Faustino, Célia; Andrade, Joana M.; Ferreira, Inês M.; Almeida, Joana F.; Rijo, Patrícia. "Lead molecules from natural products: Insight into tubercular targets". In Studies in Natural Products Chemistry, 41-84. Elsevier, 2020.
    10.1016/b978-0-12-817905-5.00002-0
  2. Santos-Rebelo, Ana; Mota, Ana Henriques; Fonseca, Leonor; Figueira, Mariana; Bastos, Ana; Macedo, Joana; Pinto, João F.; et al. "Natural Products and Nanopharmaceuticals". In Nanopharmaceuticals: Principles and Applications Vol. 2, 113-154. Springer International Publishing, 2020.
    10.1007/978-3-030-44921-6_4
  3. Rijo, Patrícia. "Isolation and purification of carnosol from Salvia officinalis". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (COCELC). 2017.
  4. Rijo, Patrícia; Diogo Matias; Cláudia Bessa; M. Fátima Simões; Catarina P. Reis; Lucília Saraiva; Patrícia Rijo. "Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy". In Studies in Natural Products Chemistry. 2016.
    10.1016/B978-0-444-63749-9.00002-5
  5. Rijo, Patrícia. "Antimicrobial abietane diterpenoids against resistant bacteria and biofilms". 2015.
  6. Rijo, Patrícia. "Antimicrobial natural products from Plectranthus plants". In Formatex Research Center; “Microbial pathogens and strategies for combating them: science, technology and education. 2013.
    Publicado
Resumo em conferência
  1. Bessa, C; Pereira, C; Maciel, C; Goncalves, J; Rijo, P; Simoes, M; Saraiva, L. "A selective activator of protein kinase Cdelta identified using yeast". 2013.
Revisão de livro
  1. Rijo, Patrícia; Pešic, Milica; Fernandes, Ana S.; Santos, Cláudia N.. "Natural Products". http://hdl.handle.net/10362/100123.
    https://doi.org/10.1155/2020/2407074
Tese / Dissertação
  1. Rijo, Patricia. "Phytochemical study and biological activities of diterpenes and derivatives from Plectranthus species". Doutoramento, 2011. http://hdl.handle.net/10451/2833.

Propriedade Intelectual

Patente
  1. Rijo, Patrícia. 2017. "ROY-BZ: A SMALL MOLECULE SELECTIVE ACTIVATOR OF PROTEIN KINASE CDELTA (PKCDELTA)".
  2. Rijo, Patrícia. 2016. "NANOSSISTEMA DE OURO COM REVESTIMENTO BIOPOLIMÉRICO E GAMA DE ABSORÇÃO NO INFRAVERMELHO PRÓXIMO E MÉTODO PARA A SUA PREPARAÇÃO".

Outros

Outra produção
  1. Increased antibacterial properties of indoline-derived phenolic Mannich bases. European journal of medicinal chemistry. 2021. Rimpilainen, T.; Nunes, A.; Calado, R.; Fernandes, A.S.; Andrade, J.; Ntungwe, E.; Spengler, G.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105818907&partnerID=MN8TOARS.
    10.26434/chemrxiv.14184929
  2. Updated review of the bioactive compounds isolated from <em>Plectranthus ecklonii </em>Benth. 2020. Patrícia Rijo; Eva Dominguez-Martin; Gabrielle Bangay; Ana Antão; Epole Ntungwe; Vera Isca; Ana Diaz-Lanza. https://doi.org/10.3390%2Fecmc2020-07278.
    10.3390/ecmc2020-07278
  3. Abietane Diterpenoids from Plectranthus spp. as a potential new class of Protein Kinase C Modulators. 2019. Patrícia Rijo. https://doi.org/10.3390%2Fecmc2019-06405.
    10.3390/ecmc2019-06405
  4. Optimization extraction study for the isolation of a bioactive diterpene from Plectranthuns ornatus Codd.. 2019. Joana Tavares; Epole Ntungwe; Vera Isca; Eva Dominguez; Patrícia Rijo. https://doi.org/10.3390%2Fecmc2019-06446.
    10.3390/ecmc2019-06446
  5. Stilbenoids in Grapes and Wine. Handbook of Dietary Phytochemicals. 2019. Noélia Duarte; Cátia Ramalhete; Patrícia Rijo; Mariana Alves Reis; Maria-José U. Ferreira; Duarte, Noélia; Ramalhete, Cátia; et al. https://doi.org/10.1007%2F978-981-13-1745-3_21-1.
    10.1007/978-981-13-1745-3_21-1
  6. Cytotoxic activity of coleon diterpenoids from Plectranthus mutabilis codd. 2019. Epole Ngolle Ntungwe; Vera Isca; Joana Tavares; Máté Vágvölgyi; Roberto Amílcar; Lucilia Saraiva; Gabriella Spengler; Attila Hunyadi; Patrícia Rijo. https://doi.org/10.3390%2Fecmc2019-06323.
    10.3390/ecmc2019-06323
  7. Design and molecular docking studies of new potential PKC-d activators based on royleanone scaffold. 2019. Patricia Rijo; Vera Isca; Epole Ntungwe; Joana Tavares; Filipa Siopa; Joana Almeida; Lucilia Saraiva; et al. https://doi.org/10.3390%2Fecmc2019-06297.
    10.3390/ecmc2019-06297
  8. Acetylcholinesterase and antioxidant evaluation of C18-functionalized ferruginol analogues. 2019. Miguel A. González-Cardenete; Alberto Yuste; Eva García-Martínez; Marisa Nicolai; Ramón Zaragozá; Patricia Rijo. https://doi.org/10.3390%2Fecmc2019-06313.
    10.3390/ecmc2019-06313
  9. Anticancer Hybrid Combinations with phenolic compounds. 2019. Eva María Domínguez Martín; Ana María Díaz Lanza; Patrícia Rijo; Célia Faustino. https://doi.org/10.3390%2Fecmc2019-06319.
    10.3390/ecmc2019-06319
  10. Molecular docking as a tool to design new royleanone derivatives for colon cancer therapy based on PKC-d modulation. 2019. VMS Isca; E Ntungwe; JF Almeida; IM Ferreira; R Pereira; F Siopa; J Almeida; et al. https://doi.org/10.1055%2Fs-0039-3399909.
    10.1055/s-0039-3399909
  11. Bio-guided phytochemical study of Plectranthus mutabilis Codd.. 2019. E Ntungwe; V Isca; M Vágvölgyie; G Spengler; A Hunyadi; P Rijo. https://doi.org/10.1055%2Fs-0039-3399860.
    10.1055/s-0039-3399860
  12. Cytotoxic Natural Products as an Approach Towards the Development of Therapeutic Agents for Precision Medicine. 2018. Rijo, P.
    10.2174/138161282436190215142414
  13. Naturally Occurring Plectranthus-derived Diterpenes with Antitumoral Activities. 2018. Garcia, C; Teodosio, C; Oliveira, C; Diaz Lanza, A; Reis, C; Duarte, N; Rijo, P.
    10.2174/1381612825666190115144241
  14. Innovative nanotechnology formulations for the treatment of yeast infections in oral mucosa. Diretores de Tese: Catarina Pinto Reis, Patrícia Mendonça Rijo, Jesús Molpeceres. La candidiasis oral es una infección provocada por hongos oportunistas que generalmente afecta a personas con inmunodeficiencia, bien por una infección viral o por un síndrome asociado a otras causas. Sin embargo, en algunos casos pueden verse afectadas personas sanas. Aunque Candida albicans es el principal agente p. 2018. Roque, Luís Miguel Vasques. http://hdl.handle.net/10437/9578.
  15. Gestão de resíduos hospitalares: estudo de referenciais de boas práticas, com base na perceção e na avaliação do risco de exposição ocupacional num hospital central. Diretores de Tese: Maria do Céu Costa, Ángel Asúnsolo del Barco. A natureza, diversidade e perigosidade dos resíduos hospitalares (RH) exige procedimentos especí¿cos na sua gestão. A necessidade de uma intervenção especi¿ca sobre os RH, é incontornável na sociedade atual, pelas exigências de Saúde Pública e Ambiental, e obriga a que as instituições de saúde integrem o processo de gestão de RH no s. 2018. Edra, Beatriz da Graça Nunes Veiga. http://hdl.handle.net/10437/9563.
  16. Lamiaceae extracts and compounds for topical application through nano delivery systems. Diretores de Tese: Patrícia Rijo, Catarina Reis, Ana M. Díaz Lanza. La resistencia a los antibióticos es uno de los principales problemas de salud que afectan a todos los continentes, ya sean países desarrollados o en desarrollo. Este tipo de infección es responsable de un elevado número de víctimas, siendo una de las más importantes causas de muerte en todo el mundo, sin una forma efectiva de ter. 2017. Pereira, Filipe Jorge da Silva. http://hdl.handle.net/10437/9575.
  17. Isolation, modeling and phytosome forms of antimicrobial and antiproliferative compounds from plectranthus spp.. Diretores de Tese : Dra. Patrícia Rijo ; Dra. Catarina Reis ; Dra. Ana Mª Díaz-Lanza. Os produtos naturais têm sido uma valiosa fonte de novos produtos farmacêuticos. As plantas de género Plectranthus L'Her (Lamiaceae) possuem uma ampla diversidade de usos etnomedicinais, que correspondem a uma indicação da presença de potenciais fármacos na sua composição. Métodos inovadores para a veiculação dos. 2016. Matias, Diogo Henrique Correia. http://hdl.handle.net/10437/7937.
  18. Ligand-functionalized nanoparticles for targeted therapy of melanoma in situ. Diretores de Tese : Dra. Patrícia Rijo ; Dra. Catarina Reis ; Dr. Jesús Molpeceres. El melanoma cutáneo es un tipo de cáncer con origen en los melanocitos que se vuelven malignos. El tratamiento del melanoma cutáneo ha evolucionado mucho en los últimos treinta años, sin embargo, no ha conseguido incrementar significativamente la supervivencia de los pacientes con cáncer avanzado. Además, el tratam. 2016. Silva, Catarina Mendes Alves de Oliveira. http://hdl.handle.net/10437/8263.
  19. Definição e Modelação Hidráulica do Controlo por Montante à Distância numa Rede de Canais com Reservatórios Associados. O controlo por jusante à distância em canais de distribuição de água permite uma resposta eficiente e automática às variações de caudal ao nível dos utentes. A profundidade controlada é a da secção mais a jusante de cada um dos trechos de canal considerado. O órgão de controlo é a comporta de admissão ao mesmo trecho, o que permite alguma antecipação na acção de controlo e, consequentemente, uma m. 2005. Rijo, Manuel; Oliveira, Patrícia. http://hdl.handle.net/10174/3468.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/12/06 “Self-assembly nanoparticles of bioactive royleanones”, “Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours” COST Action CA17104 – STRATAGEM – “NEW DIAGNOSTIC AND THERAPEUTIC TOOLS AGAINST MULTIDRUG RESISTANT TUMOURS” WG2 Hybrid Meeting
COST Action CA17104 - Angers (Angers, França)
2021/11/18 Diterpenoids from Plectranthus spp. as a starting tool in Drug Development ”; 18-19 Novembro 2021. https://bionaturalconference.com/ II Bioactive Natural Products Research Meeting - II Bio.Natural Meeting 2021 (virtual)
CBIOS - Virtual (Lisboa, Portugal)
2021/11 Self-assembly nanoparticles of natural bioactive abietane diterpenes 7th International Electronic Conference on Medicinal Chemistry
MDPI (Basel, Suiça)
2021/09/07 Abietane Diterpenoids from Plectranthus spp. as a starting tool in Cancer Research” ), September 5 – 8, 2021. Online. 69th International Congress and Annual Meeting of the. Society for Medicinal Plant and. Natural Product Research (GA
GA, virtual (Alemanha)
2021/01/27 Using Abietane Diterpenoids from Plectranthus spp. as a starting tool in Cancer Research Natural Products in Cancer Research Virtual Meeting, 27 January 2021
Virtual
2020/11/28 Using natural cytotoxic diterpenoids for innovative nanosystems FIFTH INTERNATIONAL CONFERENCE ON CANCER RESEARCH & DRUG DEVELOPMENT (Virtual).
2020/11/04 Novel class of P-glycoprotein inhibitors from Plectranthus spp. COST Action 17104 (STRATAGEM) WG3 Meeting – International Online Symposium
2020/01/17 Abietane Diterpenoids from Plectranthus spp.: a source of lead molecules 13th National Organic Chemistry Meeting - 6th National Medicinal Chemistry Meeting
(Aveiro, Portugal)
2019/11/30 Royleanone Diterpenoids from Plectranthus spp. as Lead Protein Kinase C Modulators for Cancer Therapy 2019 Sino-Portugal Forum on Traditional Medicine
(Nanchang Jiangxi, China)
2019/11/19 Abietane Diterpenoids from Plectranthus spp. as a potential new class of Protein Kinase C Modulators 5th International Electronic Conference on Medicinal Chemistry
2019/09/27 Advances in Natural Products Chemistry performed in Valencia: synthesis and biological activity of abietane diterpenoids I Bioactive Natural Products Research Meeting 2019
2019/09/26 In silico approach for design of new derivatives of 7a-acetoxy-6ß-hydroxyroyleanone from Plectranthus spp. based on PKC-d activation Flash presentation in Bio.Natural, Universidade Lusófona
2019/09/20 Plectranthus species: as a source of anti-MDR diterpenoids Working Group, WG1 meeting, COST Action: CA17104
2018/08/29 Cytotoxicity of natural halimane and labdane diterpenes by mitochondrial dysfunction in human lung cancer cells 66th Annual Meeting of GA jointly with 11th Shanghai International Conference on Traditional Chinese Medicine and Natural Medicine Shanghai, China
(China)
2018/03/03 Novel small molecule PKC¿-selective activator in colon cancer therapy 4th Meeting COST Action 1-3 March 2018, Malta
(Malta, Malta)
2017/10/25 Estudo da avaliação de eficácia do Kefir: actividade antioxidante e inibição enzimática 3rd CYTED Meeting, La Plata, Argentina, 25th October 2017.
(La Plata, Argentina)
2017/09/20 Extraction and isolation of the cytotoxic 6,7-dehydroroyleanone 2nd Training School COST CM1407, Lisbon, 18-20 September 2017.
2017/09/07 Anti-inflammatory and anti-tubercular properties screening of natural products from Plectranthus species 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) Young Researchers’ Workshop (YRW), 3-7 September 2017.
2017/09/07 Screening the dermatological potential of Plectranthus species components – antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), 3-7 September 2017.
2017/07/21 A new combined approach of Plectranthus diterpenoids as anticancer and antitubercular drugs 1º Encontro do Colégio da Química da Universidade de Lisboa, 1ECQUL, 20-21 julho 2017 (Reitoria ULisboa).
(Lisboa)
2017/05/18 Plantas medicinais: uma fonte de antibióticos International Fascination of Plants Day; Universidade Lusófona de Humanidades e Tecnologias; 18 Maio 2017
(Lisbon)
2017/04/27 Preparação de arroz vermelho glutinoso Tailandês fermentado usando Monascus purpureus NART001 isolado do arroz vermelho fermentado Chinês disponível comercialmente Jornadas Lusófonas de Nutrição; 27 de Abril de 2017
2017/03/03 Plectranthus spp. as a source of anticancer compounds 3rd COST action 1407 Meeting, Krakow, Poland, 3rd of March of 2017.

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2020 - Atual Antitumor studies of different diterpenoids and derivatives from Plectranthus spp.
Coorientador
Universidad de Alcala de Henares, Espanha
2020 - Atual Novel LOXL2 inhibitors from phytochemical-based design: effects on breast cancer progression
Coorientador
Universidad de Alcala de Henares, Espanha
2020 - Atual Scientific validation of the ethnopharmacological use of Plectranthus spp. in skin ailments
Coorientador
Universidad de Alcala de Henares, Espanha
2018 - Atual Contribuição para o estudo dos efeitos do kefir e seus subprodutos sobre a saúde da pele
Coorientador
Universidad de Alcala de Henares, Espanha
2018 - Atual New class of PKC modulators: from ethnopharmacological to nanoparticles
Orientador
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - Atual Electrochemical improvements in clinical and pharmaceutical biological processes
Coorientador
Universidad de Alcala de Henares, Espanha
2021 - 2021 Synthesis of bioactive royleanone derivatives from Plectranthus spp.
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2021 - 2021 ATIVIDADE ANTI-MICOBACTERIANA E ESTUDO ESTRUTURAL DE DITERPENOS DE HALIMANO E LABDANO OBTIDOS A PARTIR DE PLECTRANTHUS ORNATUS CODD.
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2017 - 2021 Cytotoxic Lead molecule search: Cytotoxicity and general toxicity of Seven Plectranthus species
Orientador
Universidad de Alcala de Henares, Espanha
2020 - 2020 Avaliação da actividade biológica dos extratos de Plectranthus mutabilis, P. Ciliatus, P. Xerophilos, P. Crassus e P. lucidus - defesa a realizar por vídeo conferência pública através do seguinte link: https://videoconf-colibri.zoom.us/j/91329555956
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2020 - 2020 Pesquisa de actividade biológica de extratos de Plectranthus hadiensis, P. inflexus, P. Lippio, P. Welshii e P. Mzubulensis - defesa a realizar por vídeo conferência pública através do seguinte link: https://videoconf-colibri.zoom.us/j/91207913912
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2020 - 2020 Pesquisa de actividade biológica de extratos de seis espécies de Plectranthus: P. cylindraceus, P. petiolaris, P. spicatus, P. swynnertonii, P. Welwitschii e P. woodii - defesa a realizar por vídeo conferência pública através do seguinte link: https://videoconf-colibri.zoom.us/j/98440282528
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2020 - 2020 Preparação de extractos do género Plectranthus e avaliação da actividade biológica
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2020 - 2020 Isolamento de diterpenos citotóxicos obtidos de espécies do género Plectranthus
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2020 - 2020 Estudo comparativo de eficácia de antisépticos comerciais na pele
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2019 - 2019 Preparação e análise de nanopartículas com produtos naturais
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2019 - 2019 Isolamento de um diterpeno bioactivo a partir de Plectranthus ornatus COOD
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2015 - 2019 New approaches for the treatment of the pancreatic cancer using nanodevices
Coorientador
Universidad de Alcala de Henares, Espanha
2016 - 2018 Lamiaceae extracts and compounds for topical application through nano delivery systems
Orientador
Universidad de Alcala de Henares, Espanha
2016 - 2018 Innovative nanotechnology formulations for the treatment of Candida infections
Coorientador
Universidad de Alcala de Henares, Espanha
2016 - 2018 Isolation, synthesis and nanoencapsulation of cytotoxic compounds from Plectranthus spp
Orientador
Universidad de Alcala de Henares, Espanha
2017 - 2017 Abietane Cationic Amphiphiles (ACA) - loaded polymeric microspheres to tackle resistant bacteria
Orientador
 Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2016 Unravelling new ethnopharmacological roles of Plectranthus species: biological activity screening
Orientador
 Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2016 Transdermal delivery of drugs using novel lipid nanocapsules platforms for skin cancer treatment
Coorientador
Universidad de Alcala de Henares, Espanha
2013 - 2016 Isolation, modeling and phytosome formulation of antiproliferative compounds from Plectranthus spp.,
Orientador
Universidad de Alcala de Henares, Espanha
2015 - 2015 Estudo e doseamento de compostos bioactivos do alecrim (Rosmarinus officinalis L.) e da salva (Salvia spp.)
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2015 - 2015 Compostos bioactivos e derivados do alecrim e da salva
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2015 - 2015 Estudo e separação de compostos bioactivos de espécies portuguesas de Lavanda
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal
2013 - 2013 A utilização etnobotânica do género Plectranthus
Orientador
 Ciências Farmacêuticas (Mestrado)
Universidade de Aveiro Instituto Superior de Contabilidade e Administração, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2021/05/18 - Atual Coordenadora local da Universidade Lusófona de evento no “Dia Internacional do Fascinio das Plantas 2021”, 18 de Maio 2021: https://ects.ulusofona.pt/conferencias/dia-internacional-do-fascinio-das-plantas-18-de-maio-de-2021/ (2021/05/18)
Encontro
 Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2021/11/18 - 2021/11/19 Presidente do evento e Coordenadora da Comissão Científica do congresso Internacional “II Bioactive Natural Products Research Meeting - II Bio.Natural Meeting 2021 (virtual)”; 18-19 Novembro 2021. https://bionaturalconference.com/ (2021/11/18 - 2021/11/19)
Congresso (Presidente da Comissão Organizadora)
 Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2021/01/27 - 2021/01/27 Natural Products in Cancer Research Therapy Virtual Meeting Cancer is one of the main causes of morbidity and mortality worldwide, serving as a booster for the development of new anti-cancer drugs. Natural Products from different marine and terrestrial sources such as plants, animals and/or microorganisms have played a vital role in the fight against cancer. This Meeting aims to join researchers from all over the world with different contributions in the area of natural products research to share their latest advances. (2021/01/27 - 2021/01/27)
Conferência (Presidente da Comissão Organizadora)
2019/09/26 - 2019/09/27 Bio.Natural 2019 (2019/09/26 - 2019/09/27)
Conferência (Presidente da Comissão Organizadora)
 Universidade Lusofona de Humanidades e Tecnologias, Portugal
2017/09/21 - 2017/09/22 COST ACTION CM1407 "Challenging Organic Syntheses Inspired by Nature: from Natural Products Chemistry to Drug Discovery" 4th Meeting of COST Action 1407 (Lisbon, 2017) (2017/09/21 - 2017/09/21)
Congresso (Presidente da Comissão Organizadora)
 Universidade Lusofona de Humanidades e Tecnologias, Portugal
2017/09/18 - 2017/09/20 COST ACTION CM1407 "Challenging Organic Syntheses Inspired by Nature: from Natural Products Chemistry to Drug Discovery" 2nd Training School Lisbon, 18-20 September 2017 (2017/09/18 - 2017/09/20)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade Lusofona de Humanidades e Tecnologias, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019/05/04 GESTIÓN DE RESÍDUOS HOSPITALARIOS- Estudio de referenciais de buenas prácticas com base a la percepción y evaluación del riesgo de exposición ocupacional en un Hospital Central
Arguente
 Beatriz Edra (Doutoramento)
Universidad de Alcala de Henares, Espanha
2019 Geles termorreversíveis na veiculação de fármacos
Presidente do júri
 AFONSO BATISTA DAS NEVES (Mestrado)
Universidade Lusofona de Humanidades e Tecnologias, Portugal
2018/07/19 Targeted regulation of PKC signaling pathway: Searching for new therapeutic strategies against cancer
Arguente
 Cláudia Sofia Santos Bessa (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/05/31 INDOLE ALKALOIDS AS LEADS FOR DEVELOPING EFFECTIVE ANTICANCER DRUGS TARGETING MULTIDRUG RESISTANT CANCER CELLS
Arguente principal
 Angela Paterna (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/05/05 Utilização de produtos à base de plantas, em Medicina Geral e Familiar: Perceção e atitudes de médicos da região da Grande Lisboa
Arguente principal
 Alda Pereira da Silva Oliveira (Doutoramento)
Universidad de Alcala de Henares, Espanha

Membro de associação

Nome da associação Tipo de participação
2018 - 2022 Membro da acção COST CA17104 “New diagnostic and therapeutic tools against multidrug resistant tumours” 2018-2022. acção COST CA17104 “New diagnostic and therapeutic tools against multidrug resistant tumours”
2015 - 2019 Membro da acção COST CM1407 “Challenging Organic Syntheses Inspired by Nature: from Natural Products Chemistry to Drug Discovery” 2015-2019. COST CM1407 “Challenging Organic Syntheses Inspired by Nature: from Natural Products Chemistry to Drug Discovery
2015 - 2018 Membro do Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo (CYTED) (2015-2018). Red Temática 115RT0488. “Red Iberoamericana interdisciplinaria e intersectorial para evaluar la inocuidad de alimentos de origen avícola desde la producción primaria hasta el producto final. Diseño e implementación de estrategias para mitigar riesgos y garantizar la transferencia”. Participantes (92 investigadores, becarios y técnicos pertenecientes a 8 grupos de investigación y 7 empresas de: España, Portugal, México, Brasil, Costa Rica, Guatemala, Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo (CYTED)
Distinções

Prémio

2021 Best Flash Communication Award
7th International Electronic Conference on Medicinal Chemistry, Suiça
2019 Menção honrosa para Flash apresentação oral
Bio.Natural Meeting, Portugal
2019 Bolsa de mobilidade ERASMUS PLUS STAFF Mobility
Erasmus Plus, Bélgica

Bio.Natural Meeting, Portugal
2018 Inclusiveness Target Countries (ITC) Conference Grants
European Cooperation in Science and Technology, Bélgica
2018 Menção honrosa para melhor poster
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2017 Best oral presentation
YRW Bionorica Award 2017; 11th Young Researchers Workshop of the 65th International Congress and the Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Alemanha
2017 Best Poster award and oral presentation
European Cooperation in Science and Technology, Bélgica
2016 Best Poster Award of medicinal plants and its products
2016 Best oral communication on experimental animals
SPCAL, Portugal
2016 Best oral communication with nanoformulations
24th International Conference on Bioencapsulation, Portugal
2016 Honorable mention for best oral presentation 6th International Congress of Aromatic and Medicinal Plants (CIPAM)
6th International Congress of Aromatic and Medicinal Plants (CIPAM), Portugal
2016 Best poster II Jornadas Científicas CBIOS
Grupo Lusófona, Portugal
2016 Best microscopy image
2013 Prémio Lusófona em Dermatocosmética
ALIES/SANINTER, Portugal

Outra distinção

2019 flash communication-Selecção
Bio.Natural Meeting, Portugal
2004 PhD grant SFRH/BD/19250/2004
Fundação para a Ciência e a Tecnologia, Portugal