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Identificação

Identificação pessoal

Nome completo
PEDRO CARLOS DE BARROS FERNANDES

Nomes de citação

  • FERNANDES, PEDRO

Identificadores de autor

Ciência ID
8419-9A1B-0A28
ORCID iD
0000-0003-0271-7796
Percurso profissional

Ciência

2000/01/02 - Atual Investigador (Investigação)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Docência no Ensino Superior

2016 - Atual Professor Auxiliar Convidado (Docente Universitário)
Universidade de Lisboa Instituto Superior Técnico, Portugal
1995/10/01 - Atual Professor Auxiliar (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
Projetos

Bolsa

Designação Financiadores
2012 - 2015/02 (R, S)- Resolution-Separation of secondary alcohols by enzymatic miniemulsion technology
119210
Fundação para a Ciência e a Tecnologia, I.P.
2010 - 2013/08 Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
105509
Fundação para a Ciência e a Tecnologia, I.P.
2009 - 2012/06 Sol-gel entrapped cutinase: Understanding enzyme/matrix interactions via fluorescence, NMR and DRIFT spectroscopies, and site-directed mutagenesis
64744
Fundação para a Ciência e a Tecnologia, I.P.
2007 - 2009/06 Efflux-pumps in drug resistance of Mycobacterium tuberculosis: Molecular characterisation of the efflux mechanism and use of efflux inhibitors as new anti-tubercular compounds
82329
Fundação para a Ciência e a Tecnologia, I.P.
2005 - 2008 Post-Doctoral
SFRH/BPD/20416/2004
Fundação para a Ciência e Tecnologia I.P.
2005 - 2007/12 Efflux-pumps in drug resistance of Mycobacterium tuberculosis: Molecular characterisation of the efflux mechanism and use of efflux inhibitors as new anti-tubercular compounds
59370
Fundação para a Ciência e a Tecnologia, I.P.
1998 - 2000 Solvent-tolerant bacteria as cell factories
EC Contract BIO4-CT98-0532
European Union
1998 - 2000 Solvent-tolerant bacteria as cell factories
EC Contract BIO4-CT98-0532
European Union
1997 - 1999 PhD grant
PRAXIS XXI/BD/9662/96
Junta Nacional de Investigação Cientifica e Tecnológica/ Fundação para a Ciência e a Tecnologia
1995 - 1996 PhD grant
BD 955/94
Fundação para a Ciência e a Tecnologia
1991 - 1992 MSc grant
BM 2064/91-IF
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2015 - 2019/03 INMARE - Industrial Applications of Marine Enzymes: Innovative screening and expression platforms to discover and use the functional protein diversity from the sea
634486
Research Executive Agency
Produções

Publicações

Artigo em revista
  1. Eduardo J. S. Brás; Ana Margarida Fortes; Virginia Chu; Pedro Fernandes; João Pedro Conde. 2019. "Microfluidic device for the point of need detection of a pathogen infection biomarker in grapes". The Analyst. https://doi.org/10.1039/C9AN01002E.
    10.1039/C9AN01002E
  2. Azita Navvabi; Mozhgan Razzaghi; Pedro Fernandes; Leila Karami; Ahmad Homaei. 2018. "Novel lipases discovery specifically from marine organisms for industrial production and practical applications". Process Biochemistry 70: 61-70. https://doi.org/10.1016/j.procbio.2018.04.018.
    10.1016/j.procbio.2018.04.018
  3. Dragana PC de Barros; Fátima Pinto; Ana CD Pfluck; Andreia SA Dias; Pedro Fernandes; Luís P Fonseca. 2018. "Improvement of enzyme stability for alkyl esters synthesis in miniemulsion systems by using media engineering". Journal of Chemical Technology & Biotechnology. https://doi.org/10.1002/jctb.5499.
    10.1002/jctb.5499
  4. FERNANDES, PEDRO. 2018. "Mycobacterial Response to Organic Solvents and Possible Implications on Cross-Resistance With Antimicrobial Agents". Frontiers in Microbiology. https://www.frontiersin.org/article/10.3389/fmicb.2018.00961.
    10.3389/fmicb.2018.00961
  5. FERNANDES, PEDRO. 2018. "Production, characterization, and immobilization of inulinase produced by Pseudozyma sp. (CCMB 306)". Chemical Engineering Communications 205 (8): 1060-1068. https://doi.org/10.1080/00986445.2018.1430575.
    10.1080/00986445.2018.1430575
  6. FERNANDES, PEDRO. 2018. "Development of a Point-of-Care Platform for Plant Health Assessment: A Microfluidic Approach". Proceedings. http://www.mdpi.com/2504-3900/2/13/819.
    10.3390/proceedings2130819
  7. FERNANDES, PEDRO. 2018. "Marine microbial L-asparaginase: Biochemistry, molecular approaches and applications in tumor therapy and in food industry". Microbiological Research 208: 99-112. http://www.sciencedirect.com/science/article/pii/S0944501317312673.
    https://doi.org/10.1016/j.micres.2018.01.011
  8. Eduardo JS Brás; Virginia Chu; Maria R Aires-Barros; João P Conde; Pedro Fernandes. 2017. "A microfluidic platform for physical entrapment of yeast cells with continuous production of invertase". Journal of Chemical Technology & Biotechnology. http://dx.doi.org/10.1002/jctb.5010.
    10.1002/jctb.5010
  9. Filipe Carvalho; Marco Marques; Pedro Fernandes. 2017. "Sucrose Hydrolysis in a Bespoke Capillary Wall-Coated Microreactor". Catalysts.
    10.3390/catal7020042
  10. FERNANDES, PEDRO. 2017. "Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification". Trends in Biotechnology. https://www.sciencedirect.com/science/article/pii/S0167779917302494.
    https://doi.org/10.1016/j.tibtech.2017.09.005
  11. FERNANDES, PEDRO. 2017. "A simple method for point-of-need extraction, concentration and rapid multi-mycotoxin immunodetection in feeds using aqueous two-phase systems". Journal of Chromatography A. http://www.sciencedirect.com/science/article/pii/S0021967317309718.
    https://doi.org/10.1016/j.chroma.2017.07.004
  12. FERNANDES, PEDRO. 2017. "Determination of partition coefficients of biomolecules in a microfluidic aqueous two phase system platform using fluorescence microscopy". Journal of Chromatography A 1487: 242-247. http://www.sciencedirect.com/science/article/pii/S0021967316316673.
    https://doi.org/10.1016/j.chroma.2016.12.036
  13. FERNANDES, PEDRO. 2017. "A multiplexed microfluidic toolbox for the rapid optimization of affinity-driven partition in aqueous two phase systems". Journal of Chromatography A 1515: 252-259. http://www.sciencedirect.com/science/article/pii/S002196731731138X.
    http://dx.doi.org/10.1016/j.chroma.2017.07.094
  14. Mário A.P. Nunes; Samuel Martins; M. Emilia Rosa; Pedro M.P. Gois; Pedro C.B. Fernandes; Maria H.L. Ribeiro. 2016. "Improved thermostable polyvinyl alcohol electrospun nanofibers with entangled naringinase used in a novel mini-packed bed reactor". Bioresource Technology 213: 208-215. https://doi.org/10.1016/j.biortech.2016.03.058.
    10.1016/j.biortech.2016.03.058
  15. Filipe Carvalho; Patrizia Paradiso; Benilde Saramago; Ana Maria Ferraria; Ana Maria Botelho do Rego; Pedro Fernandes. 2016. "An integrated approach for the detailed characterization of an immobilized enzyme". Journal of Molecular Catalysis B: Enzymatic 125: 64-74. https://doi.org/10.1016%2Fj.molcatb.2016.01.001.
    10.1016/j.molcatb.2016.01.001
  16. FERNANDES, PEDRO. 2016. "Miniaturization of aqueous two-phase extraction for biological applications: From micro-tubes to microchannels". Biotechnology Journal 11 (12): 1498-1512. http://dx.doi.org/10.1002/biot.201600356.
    10.1002/biot.201600356
  17. Mário A.P. Nunes; Pedro M.P. Gois; M. Emilia Rosa; Samuel Martins; Pedro C.B. Fernandes; Maria H.L. Ribeiro. 2016. "Boronic acids as efficient cross linkers for PVA: synthesis and application of tunable hollow microspheres in biocatalysis". Tetrahedron. http://www.sciencedirect.com/science/article/pii/S0040402016300801.
    http://dx.doi.org/10.1016/j.tet.2016.02.017
  18. FERNANDES, PEDRO. 2015. "Packed bed enzyme microreactor: Application in sucrose hydrolysis as proof-of-concept". Biochemical Engineering Journal.
    10.1016/j.bej.2015.04.023
  19. FERNANDES, PEDRO. 2014. "Determination of aqueous two phase system binodal curves using a microfluidic device". Journal of Chromatography A.
    10.1016/j.chroma.2014.10.035
  20. de Carvalho CC; Costa SS; Fernandes P; Couto I; Viveiros M. 2014. "Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus.". http://europepmc.org/abstract/med/24772091.
    10.3389/fphys.2014.00133
  21. Nunes, Mário A. P.; Rosa, M. Emilia; Fernandes, Pedro C. B.; Ribeiro, Maria H. L.. 2014. "Operational stability of naringinase PVA lens-shaped microparticles in batch stirred reactors and mini packed bed reactors-one step closer to industry". Bioresource Technology 164 (0): 362-370.
    http://dx.doi.org/10.1016/j.biortech.2014.04.108
  22. Figueira, J.A.; Sato, H.H.; Fernandes, P.. 2013. "Establishing the feasibility of using ß-glucosidase entrapped in lentikats and in sol-gel supports for cellobiose hydrolysis". Journal of Agricultural and Food Chemistry 61 (3): 626-634. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872862111&partnerID=MN8TOARS.
    10.1021/jf304594s
  23. Nunes, M.A.P.; Fernandes, P.C.B.; Ribeiro, M.H.L.. 2013. "Microtiter plates versus stirred mini-bioreactors in biocatalysis: A scalable approach". Bioresource Technology 136: 30-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876308534&partnerID=MN8TOARS.
    10.1016/j.biortech.2013.02.057
  24. Anes, J.; Fernandes, P.. 2013. "Towards the continuous production of fructose syrups from inulin using inulinase entrapped in PVA-based particles". Biocatalysis and Agricultural Biotechnology. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888600001&partnerID=MN8TOARS.
    10.1016/j.bcab.2013.11.006
  25. Marques, M.P.C.; Fernandes, P.; Cabral, J.M.S.; Žnidaršic-Plazl, P.; Plazl, I.. 2012. "Continuous steroid biotransformations in microchannel reactors". New Biotechnology 29 (2): 227-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855801679&partnerID=MN8TOARS.
    10.1016/j.nbt.2011.10.001
  26. Marques, M.P.C.; Walshe, K.; Doyle, S.; Fernandes, P.; De Carvalho, C.C.C.R.. 2012. "Anchoring high-throughput screening methods to scale-up bioproduction of siderophores". Process Biochemistry 47 (3): 416-421. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856230475&partnerID=MN8TOARS.
    10.1016/j.procbio.2011.11.020
  27. Silva, D.F.C.; Azevedo, A.M.; Fernandes, P.; Chu, V.; Conde, J.P.; Aires-Barros, M.R.. 2012. "Design of a microfluidic platform for monoclonal antibody extraction using an aqueous two-phase system". Journal of Chromatography A 1249: 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863784327&partnerID=MN8TOARS.
    10.1016/j.chroma.2012.05.089
  28. Nunes, M.A.P.; Fernandes, P.C.B.; Ribeiro, M.H.L.. 2012. "High-affinity water-soluble system for efficient naringinase immobilization in polyvinyl alcohol-dimethyl sulfoxide lens-shaped particles". Journal of Molecular Recognition 25 (11): 580-594. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868134599&partnerID=MN8TOARS.
    10.1002/jmr.2197
  29. Jovanovic-Malinovska, R.; Fernandes, P.; Winkelhausen, E.; Fonseca, L.. 2012. "Galacto-oligosaccharides synthesis from lactose and whey by ß-galactosidase immobilized in PVA". Applied Biochemistry and Biotechnology 168 (5): 1197-1211. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871919926&partnerID=MN8TOARS.
    10.1007/s12010-012-9850-1
  30. Bernardino, S.; Estrela, N.; Ochoa-Mendes, V.; Fernandes, P.; Fonseca, L.P.. 2011. "Optimization in the immobilization of penicillin G acylase by entrapment in xerogel particles with magnetic properties". Journal of Sol-Gel Science and Technology 58 (2): 545-556. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958784144&partnerID=MN8TOARS.
    10.1007/s10971-011-2426-7
  31. De Barros, D.P.C.; Fernandes, P.; Cabral, J.M.S.; Fonseca, L.P.. 2011. "Synthetic application and activity of cutinase in an aqueous, miniemulsion model system: Hexyl octanoate synthesis". Catalysis Today 173 (1): 95-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052267227&partnerID=MN8TOARS.
    10.1016/j.cattod.2011.05.039
  32. Santa, G.L.M.; Bernardino, S.M.S.A.; Magalhães, S.; Mendes, V.; Marques, M.P.C.; Fonseca, L.P.; Fernandes, P.. 2011. "From inulin to fructose syrups using sol-gel immobilized inulinase". Applied Biochemistry and Biotechnology 165 (1): 1-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952986394&partnerID=MN8TOARS.
    10.1007/s12010-011-9228-9
  33. Lima, D.M.; Fernandes, P.; Nascimento, D.S.; Figueiredo Ribeiro, R.C.; de Assis, S.A.. 2011. "Fructose syrup: A biotechnology asset". Food Technology and Biotechnology 49 (4): 424-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857180699&partnerID=MN8TOARS.
  34. Marques, M.P.C.; Fernandes, P.; De Carvalho, C.C.C.R.. 2011. "Process intensification platforms for application in bioengineering". 1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053959964&partnerID=MN8TOARS.
    10.1109/ENBENG.2011.6026048
  35. Fernandes, P.; Carvalho, F.; Marques, M.P.C.. 2011. "Miniaturization in biotechnology: Speeding up the development of bioprocesses". Recent Patents on Biotechnology 5 (3): 160-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054124219&partnerID=MN8TOARS.
    10.2174/187220811797579105
  36. De Alencar Figueira, J.; Dias, F.F.G.; Sato, H.H.; Fernandes, P.. 2011. "Screening of supports for the immobilization of ß-glucosidase". Enzyme Research 2011 (1). http://www.scopus.com/inward/record.url?eid=2-s2.0-84869034577&partnerID=MN8TOARS.
    10.4061/2011/642460
  37. de Carvalho, C.C.C.R.; Marques, M.P.C.; Fernandes, P.. 2011. "Recent achievements on siderophore production and application". Recent Patents on Biotechnology 5 (3): 183-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054119600&partnerID=MN8TOARS.
    10.2174/187220811797579114
  38. Marques, M.P.C.; Cabral, J.M.S.; Fernandes, P.. 2010. "Bioprocess scale-up: Quest for the parameters to be used as criterion to move from microreactors to lab-scale". Journal of Chemical Technology and Biotechnology 85 (9): 1184-1198. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956510121&partnerID=MN8TOARS.
    10.1002/jctb.2387
  39. Fernandes, P.. 2010. "Enzymes in food processing: A condensed overview on strategies for better biocatalysts". Enzyme Research 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-83455189631&partnerID=MN8TOARS.
    10.4061/2010/862537
  40. Bernardino, S.M.S.A.; Fernandes, P.; Fonseca, L.P.. 2010. "Improved specific productivity in cephalexin synthesis by immobilized PGA in silica magnetic micro-particles". Biotechnology and Bioengineering 107 (5): 753-762. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958574445&partnerID=MN8TOARS.
    10.1002/bit.22867
  41. De Barros, D.P.C.; Fernandes, P.; Cabral, J.M.S.; Fonseca, L.P.. 2010. "Operational stability of cutinase in organic solvent system: Model esterification of alkyl esters". Journal of Chemical Technology and Biotechnology 85 (12): 1553-1560. http://www.scopus.com/inward/record.url?eid=2-s2.0-78349288835&partnerID=MN8TOARS.
    10.1002/jctb.2464
  42. Fernandes, P.. 2010. "Miniaturization in biocatalysis". International Journal of Molecular Sciences 11 (3): 858-879. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950900004&partnerID=MN8TOARS.
    10.3390/ijms11030858
  43. Marques, M.P.C.; Carvalho, F.; de Carvalho, C.C.C.R.; Cabral, J.M.S.; Fernandes, P.. 2010. "Steroid bioconversion: Towards green processes". Food and Bioproducts Processing 88 (1): 12-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949271542&partnerID=MN8TOARS.
    10.1016/j.fbp.2010.01.009
  44. De Carvalho, C.C.C.R.; Fernandes, P.. 2010. "Production of metabolites as bacterial responses to the marine environment". Marine Drugs 8 (3): 705-727. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952504074&partnerID=MN8TOARS.
    10.3390/md8030705
  45. Nunes, M.A.P.; Vila-Real, H.; Fernandes, P.C.B.; Ribeiro, M.H.L.. 2010. "Immobilization of naringinase in PVA-alginate matrix using an innovative technique". Applied Biochemistry and Biotechnology 160 (7): 2129-2147. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949915103&partnerID=MN8TOARS.
    10.1007/s12010-009-8733-6
  46. Marques, M.P.C.; Cabral, J.M.S.; Fernandes, P.. 2010. "A microwell platform for the scale-up of a multistep bioconversion to bench-scale reactors: Sitosterol side-chain cleavage". Biotechnology Journal 5 (4): 402-412. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950639065&partnerID=MN8TOARS.
    10.1002/biot.200900098
  47. Fernandes, P.; Cabral, J.M.S.. 2010. "Applied Biocatalysis: An Overview". Industrial Biotechnology: Sustainable Growth and Economic Success: 227-250. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869045691&partnerID=MN8TOARS.
    10.1002/9783527630233.ch6
  48. Marques, M.P.C.; Fernandes, P.; Cabral, J.M.S.; Žnidaršic-Plazl, P.; Plazl, I.. 2010. "On the feasibility of in situ steroid biotransformation and product recovery in microchannels". Chemical Engineering Journal 160 (2): 708-714. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954818551&partnerID=MN8TOARS.
    10.1016/j.cej.2010.03.056
  49. Marques, M.P.C.; De Carvalho, C.C.C.R.; Cabral, J.M.S.; Fernandes, P.. 2010. "Scaling-up of complex whole-cell bioconversions in conventional and non-conventional media". Biotechnology and Bioengineering 106 (4): 619-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954268016&partnerID=MN8TOARS.
    10.1002/bit.22711
  50. Marques, M.P.C.; Carvalho, F.; Magalhães, S.; Cabral, J.M.S.; Fernandes, P.. 2009. "Screening for suitable solvents as substrate carriers for the microbial side-chain cleavage of sitosterol using microtitre plates". Process Biochemistry 44 (5): 556-561. http://www.scopus.com/inward/record.url?eid=2-s2.0-64049116045&partnerID=MN8TOARS.
    10.1016/j.procbio.2009.01.014
  51. Marques, M.P.C.; Magalhães, S.; Cabral, J.M.S.; Fernandes, P.. 2009. "Characterization of 24-well microtiter plate reactors for a complex multistep bioconversion: From sitosterol to androstenedione". Journal of Biotechnology 141 (3-4): 174-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349150484&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2009.03.007
  52. Fernandes, P.; Marques, M.P.C.; Carvalho, F.; Cabral, J.M.S.. 2009. "A simple method for biocatalyst immobilization using PVA-based hydrogel particles". Journal of Chemical Technology and Biotechnology 84 (4): 561-564. http://www.scopus.com/inward/record.url?eid=2-s2.0-67449116849&partnerID=MN8TOARS.
    10.1002/jctb.2080
  53. Fernandes, P.. 2009. "Liquid polymer-based media for bioconversion systems involving hydrophobic substrates". Industrial Bioprocessing 31 (7): 8-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350339780&partnerID=MN8TOARS.
  54. Bernardino, S.M.S.A.; Fernandes, P.; Fonseca, L.P.. 2009. "A new biocatalyst: Penicillin G acylase immobilized in sol-gel micro-particles with magnetic properties". Biotechnology Journal 4 (5): 695-702. http://www.scopus.com/inward/record.url?eid=2-s2.0-68049090752&partnerID=MN8TOARS.
    10.1002/biot.200800287
  55. Carvalho, F.; Marques, M.P.C.; Carvalho, C.C.C.R.d.; Cabral, J.M.S.; Fernandes, P.. 2009. "Sitosterol bioconversion with resting cells in liquid polymer based systems". Bioresource Technology 100 (17): 4050-4053. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349117272&partnerID=MN8TOARS.
    10.1016/j.biortech.2009.03.044
  56. de Barros, D.P.C.; Fonseca, L.P.; Fernandes, P.; Cabral, J.M.S.; Mojovic, L.. 2009. "Biosynthesis of ethyl caproate and other short ethyl esters catalyzed by cutinase in organic solvent". Journal of Molecular Catalysis B: Enzymatic 60 (3-4): 178-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149151029&partnerID=MN8TOARS.
    10.1016/j.molcatb.2009.05.004
  57. Marques, M.P.C.; Cabral, J.M.S.; Fernandes, P.. 2009. "High throughput in biotechnology: From shake-flasks to fully instrumented microfermentors". Recent Patents on Biotechnology 3 (2): 124-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-68549090718&partnerID=MN8TOARS.
    10.2174/187220809788700193
  58. Cattorini, S.; Marques, M.P.C.; Carvalho, F.; Chheub, V.; Cabral, J.M.S.; Fernandes, P.. 2009. "Lentikat®-based biocatalysts: Effective tools for inulin hydrolysis". Chemical and Biochemical Engineering Quarterly 23 (4): 429-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-74549204570&partnerID=MN8TOARS.
  59. Fernandes, P.; Cabral, J.M.S.. 2008. "Biocatalysis in Biphasic Systems: General". Organic Synthesis with Enzymes in Non-Aqueous Media: 189-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889272121&partnerID=MN8TOARS.
    10.1002/9783527621729.ch8
  60. Claudino, M.J.C.; Soares, D.; Van Keulen, F.; Marques, M.P.C.; Cabral, J.M.S.; Fernandes, P.. 2008. "Immobilization of mycobacterial cells onto silicone - Assessing the feasibility of the immobilized biocatalyst in the production of androstenedione from sitosterol". Bioresource Technology 99 (7): 2304-2311. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849187381&partnerID=MN8TOARS.
    10.1016/j.biortech.2007.05.007
  61. De Carvalho, C.C.C.R.; Marques, M.P.C.; Fernandes, P.; Da Fonseca, M.M.R.. 2007. "Degradation of hydrocarbons and alcohols by Rhodococcus erythropolis DCL14: A comparison in scale performance". Biocatalysis and Biotransformation 25 (2-4): 144-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-59449095073&partnerID=MN8TOARS.
    10.1080/10242420701379866
  62. Fernandes, P.; Cabral, J.M.S.. 2007. "Phytosterols: Applications and recovery methods". Bioresource Technology 98 (12): 2335-2350. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947241794&partnerID=MN8TOARS.
    10.1016/j.biortech.2006.10.006
  63. Marques, M.P.C.; de Carvalho, C.C.C.R.; Claudino, M.J.C.; Cabral, J.M.S.; Fernandes, P.. 2007. "On the feasibility of the microscale approach for a multistep biotransformation: Sitosterol side chain cleavage". Journal of Chemical Technology and Biotechnology 82 (9): 856-863. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548356971&partnerID=MN8TOARS.
    10.1002/jctb.1756
  64. Rocha, J.R.; Catana, R.; Ferreira, B.S.; Cabral, J.M.S.; Fernandes, P.. 2006. "Design and characterisation of an enzyme system for inulin hydrolysis". Food Chemistry 95 (1): 77-82. http://www.scopus.com/inward/record.url?eid=2-s2.0-31844441344&partnerID=MN8TOARS.
    10.1016/j.foodchem.2004.12.020
  65. Díaz, E.G.; Catana, R.; Ferreira, B.S.; Luque, S.; Fernandes, P.; Cabral, J.M.S.. 2006. "Towards the development of a membrane reactor for enzymatic inulin hydrolysis". Journal of Membrane Science 273 (1-2): 152-158. http://www.scopus.com/inward/record.url?eid=2-s2.0-32444445993&partnerID=MN8TOARS.
    10.1016/j.memsci.2005.12.005
  66. de Assis, S.A.; Ferreira, B.S.; Fernandes, P.; Trevisan, H.C.; Cabral, J.M.S.; Oliveira, O.M.M.F.. 2006. "Production of low methoxyl pectin using immobilized pectinmethylesterase silica from acerola (Malpighia glabra L.)". Journal of Chemical Technology and Biotechnology 81 (4): 706-709. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646195684&partnerID=MN8TOARS.
    10.1002/jctb.1382
  67. Fernandes, P.; Cabral, J.M.S.. 2006. "Microlitre/millilitre shaken bioreactors in fermentative and biotransformation processes - A review". Biocatalysis and Biotransformation 24 (4): 237-252. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747343757&partnerID=MN8TOARS.
    10.1080/10242420600667684
  68. Angelova, B.; Fernandes, P.; Spasova, D.; Mutafov, S.; Pinheiro, H.M.; Cabral, J.M.S.. 2006. "Scanning electron microscopy investigations on bis(2-ethylhexyl)phthalate treated Mycobacterium cells". Microscopy Research and Technique 69 (8): 613-617. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747880878&partnerID=MN8TOARS.
    10.1002/jemt.20327
  69. Catana, R.; Eloy, M.; Rocha, J.R.; Ferreira, B.S.; Cabral, J.M.S.; Fernandes, P.. 2006. "Stability evaluation of an immobilized enzyme system for inulin hydrolysis". Food Chemistry 101 (1): 260-266. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747096920&partnerID=MN8TOARS.
    10.1016/j.foodchem.2006.01.042
  70. Bravo Rodríguez, V.; Jurado Alameda, E.; Martínez Gallegos, J.F.; Reyes Requena, A.; García López, A.I.; Sampaio Cabral, J.M.; Fernandes, P.; Da Fonseca, L.J.P.. 2006. "Modification of the activity of an a-amylase from Bacillus licheniformis by several surfactants". Electronic Journal of Biotechnology 9 (5): 566-571. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750527351&partnerID=MN8TOARS.
    10.2225/vol9-issue5-fulltext-16
  71. Fernandes, P.. 2006. "Applied microbiology and biotechnology in the conservation of stone cultural heritage materials". Applied Microbiology and Biotechnology 73 (2): 291-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-37248998936&partnerID=MN8TOARS.
    10.1007/s00253-006-0599-8
  72. Angelova, B.; Fernandes, P.; Cruz, A.; Pinheiro, H.M.; Mutafov, S.; Cabral, J.M.S.. 2005. "Hydroxylation of androstenedione by resting Rhodococcus sp. cells in organic media". Enzyme and Microbial Technology 37 (7): 718-722. http://www.scopus.com/inward/record.url?eid=2-s2.0-25444442046&partnerID=MN8TOARS.
    10.1016/j.enzmictec.2005.04.014
  73. De Carvalho, C.C.C.R.; Marques, M.P.C.; Fernandes, P.; Da Fonseca, M.M.R.. 2005. "A simple imaging method for biomass determination". Journal of Microbiological Methods 60 (1): 135-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-9644303067&partnerID=MN8TOARS.
    10.1016/j.mimet.2004.09.014
  74. Wendhausen, R.; Frigato, M.; Fernandes, P.; Carvalho, C.C.C.R.; Cruz, A.; Pinheiro, H.M.; Cabral, J.M.S.. 2005. "Chrysotile as a support for the immobilisation of Mycobacterium sp. NRRL B-3805 cells for the bioconversion of ß-sitosterol in an organic-aqueous two-liquid phase system". Journal of Molecular Catalysis B: Enzymatic 32 (3): 61-65. http://www.scopus.com/inward/record.url?eid=2-s2.0-12344271054&partnerID=MN8TOARS.
    10.1016/j.molcatb.2004.10.001
  75. Catana, R.; Ferreira, B.S.; Cabral, J.M.S.; Fernandes, P.. 2005. "Immobilization of inulinase for sucrose hydrolysis". Food Chemistry 91 (3): 517-520. http://www.scopus.com/inward/record.url?eid=2-s2.0-11144317788&partnerID=MN8TOARS.
    10.1016/j.foodchem.2004.04.041
  76. Aparecida de Assis, S.; Fernandes, P.; Ferreira, B.S.; Cabral, J.M.S.; Mascarenhas Faria Oliveira, O.M.. 2004. "Screening of supports for the immobilization of pectinmethylesterase from acerola (Malpighia glabra L)". Journal of Chemical Technology and Biotechnology 79 (3): 277-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-1442277732&partnerID=MN8TOARS.
    10.1002/jctb.973
  77. Cruz, A.; Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 2004. "Solvent partitioning and whole-cell sitosterol bioconversion activity in aqueous-organic two-phase systems". Enzyme and Microbial Technology 34 (3-4): 342-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-0442323434&partnerID=MN8TOARS.
    10.1016/j.enzmictec.2003.11.007
  78. Cruz, A.; Angelova, B.; Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 2004. "Study of key operational parameters for the side-chain cleavage of sitosterol by free mycobacterial cells in bis-(2-ethylhexyl) phthalate". Biocatalysis and Biotransformation 22 (3): 189-194. http://www.scopus.com/inward/record.url?eid=2-s2.0-4844229254&partnerID=MN8TOARS.
    10.1080/10242420412331283297
  79. De Carvalho, C.C.C.R.; Cruz, A.; Angelova, B.; Fernandes, P.; Pons, M.N.; Pinheiro, H.M.; Cabral, J.M.S.; Da Fonseca, M.M.R.. 2004. "Behaviour of Mycobacterium sp. NRRL B-3805 whole cells in aqueous, organic-aqueous and organic media studied by fluorescence microscopy". Applied Microbiology and Biotechnology 64 (5): 695-701. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042567018&partnerID=MN8TOARS.
    10.1007/s00253-003-1508-z
  80. De Carvalho, C.C.C.R.; Da Cruz, A.A.R.L.; Pons, M.-N.; Pinheiro, H.M.R.V.; Cabral, J.M.S.; Da Fonseca, M.M.R.; Ferreira, B.S.; Fernandes, P.. 2004. "Mycobacterium sp., Rhodococcus erythropolis, and Pseudomonas putida behavior in the presence of organic solvents". Microscopy Research and Technique 64 (3): 215-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-4744372564&partnerID=MN8TOARS.
    10.1002/jemt.20061
  81. Staebler, A.; Cruz, A.; Van Der Goot, W.; Pinheiro, H.M.; Cabral, J.M.S.; Fernandes, P.. 2004. "Optimization of androstenedione production in an organic-aqueous two-liquid phase system". Journal of Molecular Catalysis B: Enzymatic 29 (1-6): 19-23. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442544587&partnerID=MN8TOARS.
    10.1016/j.molcatb.2004.01.013
  82. De Assis, S.A.; Ferreira, B.S.; Fernandes, P.; Guaglianoni, D.G.; Cabral, J.M.S.; Oliveira, O.M.M.F.. 2004. "Gelatin-immobilized pectinmethylesterase for production of low methoxyl pectin". Food Chemistry 86 (3): 333-337. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642395708&partnerID=MN8TOARS.
    10.1016/j.foodchem.2003.09.040
  83. Fernandes, P.; Cruz, A.; Angelova, B.; Pinheiro, H.M.; Cabral, J.M.S.. 2003. "Microbial conversion of steroid compounds: Recent developments". Enzyme and Microbial Technology 32 (6): 688-705. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037457699&partnerID=MN8TOARS.
    10.1016/S0141-0229(03)00029-2
  84. Fernandes, P.; Prazeres, D.M.; Cabral, J.M.. 2003. "Membrane-assisted extractive bioconversions.". Advances in biochemical engineering/biotechnology 80: 115-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037712741&partnerID=MN8TOARS.
  85. Fernandes, P.; Sommer Ferreira, B.; Sampaio Cabral, J.M.. 2003. "Solvent tolerance in bacteria: Role of efflux pumps and cross-resistance with antibiotics". International Journal of Antimicrobial Agents 22 (3): 211-216. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041833330&partnerID=MN8TOARS.
    10.1016/S0924-8579(03)00209-7
  86. Cruz, A.; Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 2002. "Effect of phase composition on the whole-cell bioconversion of ß-sitosterol in biphasic media". Journal of Molecular Catalysis B: Enzymatic 19-20: 371-375. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037010729&partnerID=MN8TOARS.
    10.1016/S1381-1177(02)00188-1
  87. Fernandes, P.; Vidinha, P.; Ferreira, T.; Silvestre, H.; Cabral, J.M.S.; Prazeres, D.M.F.. 2002. "Use of free and immobilized Pseudomonas putida cells for the reduction of a thiophene derivative in organic media". Journal of Molecular Catalysis B: Enzymatic 19-20: 353-361. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037010712&partnerID=MN8TOARS.
    10.1016/S1381-1177(02)00186-8
  88. Dias, A.C.P.; Fernandes, P.; Cabral, J.M.S; Pinheiro, H.M. 2002. "Isolation of a biodegradable sterol-rich fraction from industrial wastes". Bioresource Technology 82 (3): 253-260. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036151078&partnerID=MN8TOARS.
    10.1016/S0960-8524(01)00187-0
  89. Llanes, N.; Fernandes, P.; Léon, R.; Cabral, J.M.S.; Pinheiro, H.M.. 2001. "Conversion of ß-sitosterol by Mycobacterium sp. NRRL B-3805 cells immobilized on Celite supports". Journal of Molecular Catalysis - B Enzymatic 11 (4-6): 523-530. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035931607&partnerID=MN8TOARS.
    10.1016/S1381-1177(00)00010-2
  90. Cruz, A.; Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 2001. "Whole-cell bioconversion of ß-sitosterol in aqueous-organic two-phase systems". Journal of Molecular Catalysis - B Enzymatic 11 (4-6): 579-585. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035931532&partnerID=MN8TOARS.
    10.1016/S1381-1177(00)00047-3
  91. León, R.; Prazeres, D.M.F.; Fernandes, P.; Molinari, F.; Cabral, J.M.S.. 2001. "A multiphasic hollow fiber reactor for the whole-cell bioconversion of 2-methyl-1,3-propanediol to (R)-ß-hydroxyisobutyric acid". Biotechnology Progress 17 (3): 468-473. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034970887&partnerID=MN8TOARS.
    10.1021/bp010015g
  92. Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 1998. "Influence of some operational parameters on the bioconversion of sitosterol with immobilized whole cells in organic medium". Journal of Molecular Catalysis - B Enzymatic 5 (1-4): 307-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032530413&partnerID=MN8TOARS.
    10.1016/S1381-1177(98)00057-5
  93. León, R.; Fernandes, P.; Pinheiro, H.M.; Cabral, J.M.S.. 1998. "Whole-cell biocatalysis in organic media". Enzyme and Microbial Technology 23 (7-8): 483-500. http://www.scopus.com/inward/record.url?eid=2-s2.0-0041981949&partnerID=MN8TOARS.
    10.1016/S0141-0229(98)00078-7
  94. Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 1998. "Stability of free and immobilized Mycobacterium sp. cells in aqueous and organic media". Progress in Biotechnology 15 (C): 625-630. http://www.scopus.com/inward/record.url?eid=2-s2.0-0008605558&partnerID=MN8TOARS.
    10.1016/S0921-0423(98)80093-2
  95. Fernandes, P.; Cabrai, J.M.S.; Pinheiro, H.M.. 1996. "Immobilization of Mycobacterium sp. cells for sitosterol side chain cleavage in organic solvents". Progress in Biotechnology 11 (C): 431-436. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957098452&partnerID=MN8TOARS.
    10.1016/S0921-0423(96)80059-1
  96. Fernandes, P.; Cabral, J.M.S.; Pinheiro, H.M.. 1995. "Bioconversion of a hydrocortisone derivative in an organic-aqueous two-liquid-phase system". Enzyme and Microbial Technology 17 (2): 163-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028907925&partnerID=MN8TOARS.
Capítulo de livro
  1. Filipe Carvalho; Pedro Fernandes. 2019. "Enzymes in Sweeteners Production". 151-179. Springer Singapore. https://doi.org/10.1007/978-981-13-3263-0_9.
    10.1007/978-981-13-3263-0_9
  2. FERNANDES, PEDRO. 2018. "Enzymatic Processing in the Food Industry". Elsevier. https://www.sciencedirect.com/science/article/pii/B978008100596522341X.
    https://doi.org/10.1016/B978-0-08-100596-5.22341-X
  3. FERNANDES, PEDRO. 2016. "Microbial Transformations of Plant Secondary Metabolites". editado por Pavlov, Atanas;; Bley, Thomas, 1-41. Springer International Publishing. https://doi.org/10.1007/978-3-319-32004-5_15-1.
    10.1007/978-3-319-32004-5_15-1
  4. FERNANDES, PEDRO. 2015. "Enzyme-Mediated Novel Biotransformations in Food and Beverage Production". http://www.crcnetbase.com/doi/abs/10.1201/b19408-22.
    10.1201/b19408-22
  5. FERNANDES, PEDRO. 2013. "Production of sweeteners". http://www.crcnetbase.com/doi/abs/10.1201/b15271-15.
  6. FERNANDES, PEDRO. 2010. "Steroid bioconversion". http://onlinelibrary.wiley.com/doi/10.1002/9780470054581.eib556/abstract.
Tese / Dissertação
  1. Fernandes, Pedro Carlos de Barros; Serralheiro, Maria Luísa, 1957-; Pinheiro, Sofia M. Machado. 2011. "Desenvolvimento de métodos para estudo de inibidores da acetilcolinesterase (tratamento sintomático da Doença de Alzheimer)". Dissertação de Mestrado. http://hdl.handle.net/10451/8896.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2017 - 2017 A biocascade for the synthesis of aromatic L-amino acids Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Investigation of enzyme interaction with biorefinery lignin Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Towards an Engineering Perspective of Enzymatic Microreactors Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Miniaturized Platforms for High Throughput Biocatalysis Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Enzymatic Depolymerization of Lignin Enhanced by Electrochemistry Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 - 2016 Accessory enzymes for removal of carbohydrates from biorefinery lignin Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Evaluation of Coflore technology for enzymatic carbohydrate oxidation Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Towards the continuous production of bacterial metabolites in microfluidic environment Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Pretreatment of hemp fibers to enhance enzymatic accessibility for hemp fibers Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Development of microfluidic reactors for continuous production of extracellular metabolites Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Hydrogen-to-carbon ratio versus char yield in biomass slow pyrolysis Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Catalytic Hydrogels Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Desconstrução enzimática de biomassa celulósica residual Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Characterization of the mechanisms of adaptation of Mycobacterium to organic solvents Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015 - 2015 Adaptation of Mycobacterium to hospital disinfectants Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 - 2014 Development of a model for the calculation of the CER in a RAMOS device Engenharia Biológica (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012 - 2012 Development of an immobilized enzyme system aiming at inulin hydrolysis under continuous flow Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 - 2011 Towards production scale with microreactors. Early steps to crack the paradox Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011 - 2011 High throughput in biocatalysis: steroid bioconversions Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2010 - 2010 Miniature systems as platforms for the characterization of a multi-step bioconversion in silicone media Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal