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Identificação

Identificação pessoal

Nome completo
Alba Orea-Soufi

Nomes de citação

  • Orea-Soufi, Alba

Identificadores de autor

Ciência ID
6C16-45B1-8301
ORCID iD
0000-0001-9264-6519

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Medicina Clínica - Oncologia
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2)
Espanhol; Castelhano (Idioma materno)
Português Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B1)
Formação
Grau Classificação
2015/10/01 - 2022/07/02
Concluído
Bioquímica, biología molecular y biomedicina (Doctor)
Universidad Complutense de Madrid, Espanha
"Papel de la pseudoquinasa Tribales 3 en cáncer de mama: estudios mecanisticos e implicaciones en el pronóstico del subtipo luminal" (TESE/DISSERTAÇÃO)
Cum laude
2014/09/01 - 2015/07/15
Concluído
Bioquímica, biología molecular y biomedicina (Master)
Universidad Complutense de Madrid, Espanha
9,61
2010/09/01 - 2014/07/15
Concluído
Bioquímica (Bachelor)
Universidad Complutense de Madrid, Espanha
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2022/02/07 - Atual Pós-doutorado (Investigação) Universidade do Algarve, Portugal
2015/10/01 - 2021/09/30 Investigador (Investigação) Universidad Complutense de Madrid, Espanha
Projetos

Projeto

Designação Financiadores
2022/02/01 - Atual Overcoming drug resistance in glioblastoma
PTDC/MED-ONC/4167/2020
Investigador Pós-doutorado
Universidade do Algarve, Portugal

Algarve Biomedical Center Research Institute, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019 - 2021 Mechanism of autophagy-mediated cancer cell death and participation of autophagy associated genes in the control of tumorigenesis
Pi18/00442
Investigador
Universidad Complutense de Madrid, Espanha
Gobierno de España
Concluído
2016 - 2019 TRAIN
TRAIN-GA721532
Investigador
European Commission Marie Sklodowska-Curie Actions
Concluído
2016 - 2018 Role of autophagy in cancer: autophagy-mediated cell death in tumoral cells and participation of autophagy regulatory genes in the control of tumorigenesis
PI15/00339
Investigador
Gobierno de España
Concluído
Produções

Publicações

Artigo em revista
  1. Orea-Soufi, Alba; Paik, Jihye; Bragança, José; Donlon, Timothy A.; Willcox, Bradley J.; Link, Wolfgang. Autor correspondente: Link, Wolfgang. "FOXO transcription factors as therapeutic targets in human diseases". Trends in Pharmacological Sciences 43 12 (2022): 1070-1084. http://dx.doi.org/10.1016/j.tips.2022.09.010.
    10.1016/j.tips.2022.09.010
  2. Hernández-Quiles, Miguel; Baak, Rosalie; Orea-Soufi, Alba; Borgman, Anouska; den Haan, Suzanne; Sobrevals Alcaraz, Paula; Jongejan, Aldo; et al. Autor correspondente: Kalkhoven, Eric. "TRIB3 Modulates PPAR¿-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells". International Journal of Molecular Sciences 23 18 (2022): 10535. http://dx.doi.org/10.3390/ijms231810535.
    10.3390/ijms231810535
  3. Orea-Soufi, Alba; Castillo-Lluva, Sonia; Salvador-Tormo, Nélida; Martín-Cabrera, Paola; Recuero, Silvia; Gabicagogeascoa, Estíbaliz; Moreno-Valladares, Manuel; et al. "The Pseudokinase TRIB3 Negatively Regulates the HER2 Receptor Pathway and Is a Biomarker of Good Prognosis in Luminal Breast Cancer". Cancers 13 21 (2021): 5307. http://dx.doi.org/10.3390/cancers13215307.
    10.3390/cancers13215307
  4. Salazar, María; Lorente, Mar; Orea-Soufi, Alba; Dávila, David; Erazo, Tatiana; Lizcano, José; Carracedo, Arkaitz; Kiss-Toth, Endre; Velasco, Guillermo. Autor correspondente: Velasco, Guillermo. "Oncosuppressive functions of tribbles pseudokinase 3". Biochemical Society Transactions 43 5 (2015): 1122-1126. http://dx.doi.org/10.1042/bst20150124.
    10.1042/bst20150124
Capítulo de livro
  1. Orea-Soufi, Alba; Dávila, David; Salazar, María; Lorente, Mar; Velasco, Guillermo. Autor correspondente: Velasco, Guillermo. "Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity". 51-59. Springer New York, 2019.
    10.1007/978-1-4939-8900-3_5
Atividades

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2024/01/26 - 2024/01/26 Participation in congress contribution "the impact of metabolic modulatiors on the viability of glioblastoma cells"
Oficina (workshop)
ix clinical biochemistry workshop
Sociedade Portuguesa de Bioquímica, Portugal
2021/10/26 - 2021/10/29 Poster presentation "Role of TRIB3 pseudokinase in luminal breast cancer"
Congresso
XIX congress of the spanish society of molecular biology
sociedad española de biología celular, Espanha
2018/11/06 - 2018/11/08 Poster presentation "Role of TRIB3 pseudokinase in breast cancer development and progression"
Congresso
16th ASEICA International Congress
Asociación Española de Investigación sobre el Cáncer, Espanha
2018 - 2018 Training seminar on university teaching skills (30 hours)
Oficina (workshop)
Training seminar on university teaching skills
Gobierno de Espana Ministerio de Educación Cultura y Deporte, Espanha
2017/11/15 - 2017/11/17 Participation in congress contribution "Ambra1 regulates epitheliala to mesenchymal transition in squamous cell carcinoma cells through the TGFb pathway"
Congresso
2nd NEAR Meeting
sociedad española de autofagia, Espanha
2017/11/15 - 2017/11/17 Participation in congress contribution "Ambra1, a novel biomarker of prognosis in human squamous cell carcinoma"
Congresso
2nd NEAR Meeting
sociedad española de autofagia, Espanha
2017/05/07 - 2017/05/09 Poster presentation "Dual role of TRIB3 pseudokinase in breast cancer development and progression"
Congresso
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Role of TRIB3 in the regulation of cancer generation, progression and response to therapy"
Congresso
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Does Tribbles 3 act as an onco-suppressor in prostate cancer cells?"
Congresso
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017/05/07 - 2017/05/09 Participation in congress contribution "Potential role of TRIB3 in the development of hepatocelular carcinoma"
Conferência
2nd International Symposium on Tribbles and Disease (ISTD 2018)
2017 - 2017 Course in medical neuro-oncology (8 hours)
Oficina (workshop)
Course in medical neuro-oncology
grupo español de investigación en neurooncología, Espanha
2016/09/05 - 2016/09/08 Poster presentation "Dual role of the pseudokinase TRIB3 in the development of breast "
Congresso
XXXIX Congreso de la Sociedad Española de Bioquímica y Biología Molecular
Sociedad Española de Bioquímica y Biología Molecular, Espanha
2016/06/12 - 2016/06/15 Participation in congress contribution "Ambra1, a new biomarker in human squamous cell carcinoma"
Congresso
1st NEAR Meeting
sociedad española de autofagia, Espanha
2016 - 2016 Gas Safety Course in the Laboratory (4.5 hours)
Oficina (workshop)
Gas Safety Course in the Laboratory
Universidad Complutense de Madrid, Espanha
2016 - 2016 Course on proteomics "VII Hands-on Course in Ultrafast Sample Treatment for Proteomic" (20 hours)
Oficina (workshop)
VII Hands-on Course in Ultrafast Sample Treatment for Proteomic
Associação Científica Proteomass, Portugal
2015/06/28 - 2015/06/29 Participation in congress contribution "Role of Ambra1 in squamous cell carcinoma"
Congresso
3rd Meeting of the Spanish Autophagy Group
sociedad española de autofagia, Espanha
2015/04/22 - 2015/04/22 Poster presentation "Potential role for the pseudokinase TRIB3 in the modulation of the invasiveness and metastatic ability of tumour cells"
Congresso
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015/04/22 - 2015/04/22 participation in congress contribution ". Dual role of the pseudokinase TRIB3 in the development of breast cancer"
Congresso
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015/04/22 - 2015/04/22 Participation in congress contribution "Tumor suppressor role of TRIB3"
Congresso
Meeting Tribbles Pseudokinases. At the crossroads of metabolism, cancer, inmunity and development
2015 - 2015 Prevention of biological risk in research laboratories and animal facilities (4 hours)
Oficina (workshop)
Prevention of biological risk in research laboratories and animal facilities
Universidad Complutense de Madrid, Espanha
2015 - 2015 Animal Experimentation Course (category B; 40 hours)
Oficina (workshop)
Animal Experimentation Course (category B)
Centro de Estudios Biosanitarios, Espanha

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019 - 2020 Fundamentals of genetic and genomic engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Espanha
2019 - 2020 Industrial Biochemistry Degree in Chemical Engineering (Bachelor) Universidad Complutense de Madrid, Espanha
2019 - 2020 Biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Espanha
2018 - 2019 biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Espanha
2018 - 2019 Enzyme biotechnology degree in biology (Bachelor) Universidad Complutense de Madrid, Espanha
2017 - 2018 Pathology and Clinical Biochemistry degree in biology (Bachelor) Universidad Complutense de Madrid, Espanha
2017 - 2018 Fundamentals of Genetic and Genomic Engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Espanha
2016 - 2017 Integrated Laboratory of Biochemistry and Molecular Biology 2 Degree in Biochemistry (Bachelor) Universidad Complutense de Madrid, Espanha
2015 - 2016 Fundamentals of Genetic and Genomic Engineering degree in biology (Bachelor) Universidad Complutense de Madrid, Espanha
2014 - 2015 biochemistry Degree in Biology (Bachelor) Universidad Complutense de Madrid, Espanha

Tutoria

Tópico Nome do aluno
2023 - 2024 Study of the mechanism underlying TRIB2-mediated resistance in glioblastoma Carlos Amenábar
2023 - 2023 impacto do gene TRIB2 no metabolismo energético de glioblastomas Víctor Yassuda
2022 - 2023 Contribution of Tribbles protein family members in glioblastoma cells Letícia Leite
2020 - 2021 Role of TRIB3 in luminal breast cancer migration and invasion Paola Martín
2019 - 2020 Role of TRIB3 in luminal breast cancer therapy response Silvia Recuero
Distinções

Prémio

2015 Best record of the master promotion
Universidad Complutense de Madrid, Espanha
2014 5th best record of the bachelor promotion
Universidad Complutense de Madrid, Espanha