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My name is Duangnapa Kiriwan, and I have been working as a research assistant for four years under the supervision of Assoc.Prof.Dr. Kiattawee Choowongkomon. I finished a Bachelor's degree in biochemistry from Burapha University in Thailand and then a Master's degree in genetic engineering and bioinformatics from Kasetsart University in 2021. I've authored 15 papers in peer-reviewed journals that have been cited in ISI Web of Science/Scopus (2 as first author, 13 as co-author). My research interests include computer-assisted drug design Molecular modelling, Molecular docking and Molecular dynamics simulation and AI-algorithm involved inhibitors design.
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Identificação

Identificação pessoal

Nome completo
Duangnapa Kiriwan

Nomes de citação

  • kiriwan, duangnapa

Identificadores de autor

Ciência ID
6812-40DD-2209
ORCID iD
0000-0003-4824-7398
Scopus Author Id
57210797600

Endereços de correio eletrónico

  • up202310671@up.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Tailandês (Idioma materno)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2024/02 - 2028
Em curso
 Química Sustentável (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal
2017/07 - 2021/06/16
Concluído
 Genetic Engineering and Bioinformatics (Master)
Department of Biochemistry, Kasetsart university, Bangkok, Thailand, Tailândia
"In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp) And Human Epidermal Growth Factor Receptor Tyrosine Kinase Towards the Identification of Potential Inhibitors " (TESE/DISSERTAÇÃO)
 3.83/4.00, 19/20
2011/01/29 - 2015/04/07
Concluído
 Biochemistry (Bachelor)
Department of Biochemistry, Burapha university, Bangkok, Thailand, Tailândia
"Homologous protein interaction network and functional analysis of salicylic acid biosynthesis pathway" (TESE/DISSERTAÇÃO)
 2.92/4.00, 16/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/01/07 - Atual Assistente de Investigação (carreira) (Investigação) Kasetsart University Department of Biochemistry, Tailândia
Department of Biochemistry, Kasetsart university, Bangkok, Thailand, Tailândia
2022/01/17 - 2022/08/26 Estagiário de Investigação (Investigação) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Kasetsart University, Tailândia
2020/03/01 - 2020/06/23 Estagiário de Investigação (Investigação) Universidade do Porto Departamento de Química e Bioquímica, Portugal
Kasetsart University, Tailândia
2019/07/01 - 2019/07/19 Estagiário de Investigação (Investigação) Institute of Quantum Beam Science of Ibaraki University , Japão
Kasetsart University, Tailândia
2018/06/01 - 2018/08/31 Estagiário de Investigação (Investigação) Pharmaceutical Science, University of Vienna, Austria, Áustria
Kasetsart University, Tailândia
2015/04/14 - 2015/09/30 Assistente de Investigação (carreira) (Investigação) Department of Biochemistry, Burapha university, Bangkok, Thailand, Tailândia
Department of Biochemistry, Burapha university, Bangkok, Thailand, Tailândia
Produções

Publicações

Artigo em revista
  1. Tran, Thi-Minh-Dinh; Aonbangkhen, Chanat; Duong, Thuc-Huy; Nguyen, Thu-Hoang-Mai; Ho, Minh-Truong-Tho; Chavasiri, Warinthorn; Wongsuwan, Sutthida; et al. "Diphenyl ethers from the cultured lichen mycobiont of Graphis handelii Zahlbr". Heliyon 10 4 (2024): e25763. http://dx.doi.org/10.1016/j.heliyon.2024.e25763.
    10.1016/j.heliyon.2024.e25763
  2. Suwattanasophon, Chonticha; Mistlberger-Reiner, Agnes; Alberdi-Cedeño, Jon; Pignitter, Marc; Somoza, Veronika; König, Jürgen; Lamtha, Thomanai; et al. "Identification of the Brucea javanica Constituent Brusatol as a EGFR-Tyrosine Kinase Inhibitor in a Cell-Free Assay". ACS Omega 8 31 (2023): 28543-28552. http://dx.doi.org/10.1021/acsomega.3c02931.
    10.1021/acsomega.3c02931
  3. Thitinan Aiebchun; Natchaya Rasri; Duangnapa Kiriwan; Suradej Siripattanapipong; kiattawee choowongkomon. "In Vitro and In Silico Studies of Kinase Inhibitor of MAPK3 Protein to Determine Leishmania martiniquensis Treatment". Acta Parasitologica (2023): http://dx.doi.org/10.1007/s11686-023-00659-0.
    10.1007/s11686-023-00659-0
  4. Rattanabunyong, Siriluk; Choengpanya, Khuanjarat; Suwattanasophon, Chonticha; Kiriwan, Duangnapa; Wolschann, Peter; Lamtha, Thomanai; Shaikh, Abdul Rajjak; Rattanasrisomporn, Jatuporn; Choowongkomon, Kiattawee. "Biochemical and structural comparisons of non-nucleoside reverse transcriptase inhibitors against feline and human immunodeficiency viruses". Journal of Veterinary Science 24 5 (2023): http://dx.doi.org/10.4142/jvs.22326.
    10.4142/jvs.22326
  5. Buabarn Kuaprasert; Penchit Chitnumsub; Ubolsree Leartsakulpanich; pinpunya riangrungroj; Wipa Suginta; Saovanee Leelayoova; Mathirut Mungthin; et al. "Dual role of azo compounds in inhibiting Plasmodium falciparum adenosine deaminase and hemozoin biocrystallization". Experimental Parasitology 243 (2022): 108384-108384. http://dx.doi.org/10.1016/j.exppara.2022.108384.
    10.1016/j.exppara.2022.108384
  6. Lueacha Tabtimmai; Prapasri Supakun; Borvornvat Toviwek; Nattanan Jiwacharoenchai; Duangnapa Kiriwan; Thitinan Aiebchun; Matthew Paul Gleeson; kiattawee choowongkomon. "4-Aryl-N-phenylpyrimidin-2-amines targeting EGFR-tyrosine kinase attenuated EGFR-expressing cell lines". European Journal of Medicinal Chemistry Reports 5 (2022): 100062-100062. http://dx.doi.org/10.1016/j.ejmcr.2022.100062.
    10.1016/j.ejmcr.2022.100062
  7. "Identification of tripeptides against tyrosine kinase domain of EGFR for lung cancer cell inhibition by in silico and in vitro studies". Chemical Biology & Drug Design 99 3 (2022): 456-469. http://dx.doi.org/10.1111/cbdd.14010.
    10.1111/cbdd.14010
  8. "A novel cyclic NP1 reveals obstruction of EGFR kinase activity and attenuation of EGFR-driven cell lines". Journal of Cellular Biochemistry 123 2 (2022): 248-258. http://dx.doi.org/10.1002/jcb.30160.
    10.1002/jcb.30160
  9. "Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development". Protein Engineering, Design and Selection 34 (2021): http://dx.doi.org/10.1093/protein/gzab030.
    10.1093/protein/gzab030
  10. Wongsamart, R.; Kiriwan, D.; Suwattanasophon, C.; Yokthongwattana, K.; Choowongkomon, K.. "Computational analysis of homo-dimerization of chloroplast-localized chaperonin from the alga Chlamydomonas reinhardtii". Agriculture and Natural Resources 55 5 (2021): http://dx.doi.org/10.34044/j.anres.2021.55.5.03.
    10.34044/j.anres.2021.55.5.03
  11. "Molecular dynamics, MM/PBSA and in vitro validation of a novel quinazoline-based EGFR tyrosine kinase inhibitor identified using structure-based in silico screening". Journal of Molecular Graphics and Modelling 99 (2020): 107639-107639. http://dx.doi.org/10.1016/j.jmgm.2020.107639.
    10.1016/j.jmgm.2020.107639
  12. "Chamuangone from Garcinia cowa leaves inhibits cell proliferation and migration and induces cell apoptosis in human cervical cancer in vitro". Journal of Pharmacy and Pharmacology 72 3 (2020): 470-480. http://dx.doi.org/10.1111/jphp.13216.
    10.1111/jphp.13216
  13. "Cell-penetrable nanobodies (transbodies) that inhibit the tyrosine kinase activity of EGFR leading to the impediment of human lung adenocarcinoma cell motility and survival". Journal of Cellular Biochemistry 120 10 (2019): 18077-18087. http://dx.doi.org/10.1002/jcb.29111.
    10.1002/jcb.29111
  14. "In Vitro Antimalarial Activity and Cytotoxity of 20 Ethanolic Crude Extracts from Thai Herbs Against Plasmodium Falciparum TM267". Songklanagarind Medical Journal 35 2 (2017): 109-109. http://dx.doi.org/10.31584/smj.2017.35.2.693.
    10.31584/smj.2017.35.2.693
Poster em conferência
  1. kiriwan, duangnapa; Choowongkomon, K.. Autor correspondente: Choowongkomon, K.. "In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp)". Trabalho apresentado em World Rabies Day 2020, Thailand, 2020.
  2. kiriwan, duangnapa; Choowongkomon, K.. Autor correspondente: Choowongkomon, K.. "Virtual Screening with Rabies virus RNA Dependent RNA Polymerase (RdRp) to Design Viral Therapeutics". Trabalho apresentado em 14th International Symposium of the Protein Society of Thailand (PST2019), 2019.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/07/13 In Silico Structural Elucidation of The Rabies RNA-Dependent RNA Polymerase (RdRp)" Asian workshop of Experiment and Theory in Quantum Beam Molecular Science 2019
(Mito, Japão)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/04/18 - 2019/04/19 Protein Bioinformatics workshop (2019/04/18 - 2019/04/19)
Oficina (workshop) (Outra)
 Kasetsart University Department of Biochemistry, Tailândia