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Alexandre Sepriano. Concluiu o(a) Mestrado integrado em Medicine em 2009 pelo(a) Centro Académico de Medicina de Lisboa e Doutoramento em Rheumatology em 2020 pelo(a) Leids Universitair Medisch Centrum. Publicou 105 artigos em revistas especializadas. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Clínica com ênfase em Reumatologia.
Identificação

Identificação pessoal

Nome completo
Alexandre Sepriano

Nomes de citação

  • Sepriano, Alexandre
  • Sepriano A

Identificadores de autor

Ciência ID
5E1B-9976-5CE4
ORCID iD
0000-0003-1954-0229
Google Scholar ID
https://scholar.google.pt/citations?hl=pt-PT&user=0sEAaR0AAAAJ
Scopus Author Id
55266526300

Endereços de correio eletrónico

  • alexsepriano@gmail.com (Profissional)
  • alexandre.sepriano@nms.unl.pt (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Reumatologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2021 - 2024
Em curso
Pos-doc (Pós-doutoramento)
Universidade Nova de Lisboa Medical School, Portugal
2016 - 2020
Concluído
Rheumatology (Doutoramento)
Leids Universitair Medisch Centrum, Países Baixos
Approved Cum Laude (with distinction)
2011 - 2016
Concluído
Rheumatology (Especialização pós-licenciatura)
Centro Hospitalar de Lisboa Ocidental EPE Serviço de Reumatologia, Portugal
19.7
2013 - 2014
Concluído
Portugal Program's Clinical Scholars Research Training (CSRT) Certificate Program (Especialização pós-licenciatura)
Harvard Medical School, Estados Unidos
Approved
2010 - 2011
Concluído
General Medicine (Especialização pós-licenciatura)
Centro Académico de Medicina de Lisboa, Portugal
19.3
2003 - 2009
Concluído
Medicine (Mestrado integrado)
Centro Académico de Medicina de Lisboa, Portugal
17
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2021 - 2024 Pós-doutorado (Investigação) Universidade Nova de Lisboa Medical School, Portugal
Universidade Nova de Lisboa Medical School, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2022 - Atual Professor Auxiliar Convidado (Docente Universitário) Universidade Nova de Lisboa Medical School, Portugal
Universidade Nova de Lisboa Medical School, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento
Empregador
2020 - Atual Assistente (Médica) Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Portugal
Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Portugal
2011 - 2016 Interno (Médica) Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Portugal
Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2023 - Atual Leader of Young ASAS (Assessment of Spondylarthritis International Society) Assessment of Spondylarthritis International Society, Países Baixos
Assessment of Spondylarthritis International Society, Países Baixos
2022 - Atual Member of EULAR Research subcommittee for Epidemiology and Health Services European League Against Rheumatism, Suiça
European League Against Rheumatism, Suiça
2021 - Atual Member of EULAR Quality of Care committee European League Against Rheumatism, Suiça
European League Against Rheumatism, Suiça
2020 - Atual Editor in chief ARP Rheumatology (official journal of the Portuguese Society of Rheumatology) Sociedade Portuguesa de Reumatologia, Portugal
Sociedade Portuguesa de Reumatologia, Portugal
2019 - 2020 Chair of the Emerging EULAR network (EMEUNET). European League Against Rheumatism, Suiça
European League Against Rheumatism, Suiça
Projetos

Bolsa

Designação Financiadores
2016/05 - 2020/05 Axial Spondyloarthritis: from a conceptual framework to clinical practice
SFRH/BD/108246/2015
Universidade de Coimbra
2015/04 - 2015/09 Retention rate and predictive factors of TNF blockers discontinuation in patients with spondyloarthritis in clinical practice
EULAR scientific training bursary for young fellows
European League Against Rheumatism
2015/01 - 2015/09 Retention rate and predictive factors of TNF blockers discontinuation in patients with spondyloarthritis in clinical practice Assessment of SpondyloArthritis international Society
Produções

Publicações

Artigo em jornal
  1. Branco, Jaime; Sequeira, Maria Luisa; Santos, Inês Da Costa; Amador, Rita; Domingues, Lucia; Crespo, Carolina; Rodrigues-Manica, Santiago; et al. "THU0403 AXIAL SPONDYLOARTHRITIS INDUCES MUSCLE DISFUNCTION, THE ROLE OF BODY COMPOSITION PARAMETERS: MYOSPA STUDY", Annals of the Rheumatic Diseases , 2019, https://ard.bmj.com/content/annrheumdis/78/Suppl_2/488.2.full.pdf.
    10.1136/annrheumdis-2019-eular.6817
Artigo em revista
  1. Anna Molto; Clementina López-Medina; Alexandre Sepriano; Sofia Ramiro; Manouk de Hooge; Miranda van Lunteren; Victoria Navarro-Compán; Daniel Wendling; Maxime Dougados. "Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort". Annals of the Rheumatic Diseases (2024): https://doi.org/10.1136/ard-2023-225184.
    10.1136/ard-2023-225184
  2. Ana Bento da Silva; Maria Helena Lourenço; Sofia Ramiro; Louise Falzon; Jaime Cunha-Branco; Désirée van der Heijde; Robert Landewé; et al. Autor correspondente: Bento da Silva, Ana. "Performance of clinical, laboratory and imaging features for diagnosing spondyloarthritis—a systematic literature review and meta-analysis". Rheumatology 74 4 (2024): 86-87. https://doi.org/10.1093/rheumatology/keae065.
    10.1093/rheumatology/keae065
  3. Xabier Michelena; Alexandre Sepriano; Sizheng Steven Zhao; Clementina López-Medina; Eduardo Collantes-Estévez; Pilar Font-Ugalde; Xavier Juanola; Helena Marzo-Ortega. "Exploring the unifying concept of spondyloarthritis: a latent class analysis of the REGISPONSER registry". Rheumatology (2024): https://doi.org/10.1093/rheumatology/keae005.
    10.1093/rheumatology/keae005
  4. Alexandre Sepriano; Bastiaan van Dijk; Sofia Ramiro; Annette van der Helm-van Mil; Bernard Combe; Dirkjan van Schaardenburg; Maarten de Wit; et al. "Distinction and prognosis of early arthritis phenotypes: an analysis in three European cohorts". RMD Open (2023): https://doi.org/10.1136/rmdopen-2023-003611.
    10.1136/rmdopen-2023-003611
  5. Sofia Ramiro; Robert Landewé; Désirée van der Heijde; Alexandre Sepriano; Oliver FitzGerald; Mikkel Østergaard; Joanne Homik; et al. "Stricter treat-to-target in RA does not result in less radiographic progression: a longitudinal analysis in RA BIODAM". Rheumatology (2023): https://doi.org/10.1093/rheumatology/kead021.
    10.1093/rheumatology/kead021
  6. Sytske Anne Bergstra; Alexandre Sepriano; Arvind Chopra; Lai-Ling Winchow; David Vega-Morales; Karen Salomon-Escoto; Xanthe M E Matthijssen; Robert BM Landewé. "Country-level socioeconomic status relates geographical latitude to the onset of RA: a worldwide cross-sectional analysis in the METEOR registry". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2023-224080.
    10.1136/ard-2023-224080
  7. Rodrigues-Manica, Santiago; Sepriano, Alexandre; Ramiro, Sofia; Landewé, Robert; Claudepierre, Pascal; Moltó, Anna; Dougados, Maxime; van Lunteren, Miranda; van der Heijde, Désirée. "Bone marrow edema in the sacroiliac joints is associated with the development of structural lesions at the same anatomical location over time in patients with axial spondyloarthritis". Seminars in Arthritis and Rheumatism 61 (2023): 152225. http://dx.doi.org/10.1016/j.semarthrit.2023.152225.
    10.1016/j.semarthrit.2023.152225
  8. Sofia Ramiro; Elena Nikiphorou; Alexandre Sepriano; Augusta Ortolan; Casper Webers; Xenofon Baraliakos; Robert BM Landewé; Désirée van der Heijde. "Response to: Correspondence on "ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update" by Ramiroet al". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2023-223937.
    10.1136/ard-2023-223937
  9. Alexandre Sepriano; Andreas Kerschbaumer; Sytske Anne Bergstra; Josef S Smolen; Désirée van der Heijde; Roberto Caporali; Christopher J Edwards; et al. "Safety of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223357.
    10.1136/ard-2022-223357
  10. Casper Webers; Augusta Ortolan; Alexandre Sepriano; Louise Falzon; Xenofon Baraliakos; Robert B M Landewé; Sofia Ramiro; Désirée van der Heijde; Elena Nikiphorou. "Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223298.
    10.1136/ard-2022-223298
  11. Sofia Ramiro; Elena Nikiphorou; Alexandre Sepriano; Augusta Ortolan; Casper Webers; Xenofon Baraliakos; Robert B M Landewé; et al. "ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223296.
    10.1136/ard-2022-223296
  12. Sytske Anne Bergstra; Alexandre Sepriano; Andreas Kerschbaumer; Désirée van der Heijde; Roberto Caporali; Christopher John Edwards; Patrick Verschueren; et al. "Efficacy, duration of use and safety of glucocorticoids: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223358.
    10.1136/ard-2022-223358
  13. Andreas Kerschbaumer; Alexandre Sepriano; Sytske Anne Bergstra; Josef S Smolen; Désirée van der Heijde; Roberto Caporali; Christopher John Edwards; et al. "Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223365.
    10.1136/ard-2022-223365
  14. Augusta Ortolan; Casper Webers; Alexandre Sepriano; Louise Falzon; Xenofon Baraliakos; Robert BM Landewé; Sofia Ramiro; Désirée van der Heijde; Elena Nikiphorou. "Efficacy and safety of non-pharmacological and non-biological interventions: a systematic literature review informing the 2022 update of the ASAS/EULAR recommendations for the management of axial spondyloarthritis". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223297.
    10.1136/ard-2022-223297
  15. Josef S Smolen; Robert B M Landewé; Sytske Anne Bergstra; Andreas Kerschbaumer; Alexandre Sepriano; Daniel Aletaha; Roberto Caporali; et al. "EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update". Annals of the Rheumatic Diseases (2023): https://doi.org/10.1136/ard-2022-223356.
    10.1136/ard-2022-223356
  16. Rosalinde Stal; Alexandre Sepriano; Floris Alexander van Gaalen; Xenofon Baraliakos; Rosaline van den Berg; Monique Reijnierse; Juergen Braun; Robert B M Landewé; Désirée van der Heijde. "Associations between syndesmophytes and facet joint ankylosis in radiographic axial spondyloarthritis patients on low-dose CT over 2 years". Rheumatology (2022): https://doi.org/10.1093/rheumatology/keac176.
    10.1093/rheumatology/keac176
  17. Rosalinde Stal; Xenofon Baraliakos; Désirée van der Heijde; Floris van Gaalen; Sofia Ramiro; Rosaline van den Berg; Monique Reijnierse; et al. "Role of vertebral corner inflammation and fat deposition on MRI on syndesmophyte development detected on whole spine low-dose CT scan in radiographic axial spondyloarthritis". RMD Open (2022): https://doi.org/10.1136/rmdopen-2022-002250.
    10.1136/rmdopen-2022-002250
  18. Ovseiko, Pavel, V; Gossec, Laure; Andreoli, Laura; Kiltz, Uta; van Mens, Leonieke; Hassan, Neelam; van der Leeden, Marike; et al. "Gender equity in academic rheumatology, current status and potential for improvement: a cross-sectional study to inform an EULAR task force". RMD Open (2022): https://publons.com/wos-op/publon/54599743/.
    10.1136/RMDOPEN-2022-002518
  19. Sepriano, Alexandre; Ramiro, Sofia; van der Heijde, Désirée; Dougados, Maxime; Claudepierre, Pascal; Feydy, Antoine; Reijnierse, Monique; et al. "Which imaging outcomes for axSpA are most sensitive to change?". Arthritis Care & Research (2022): http://hdl.handle.net/10362/132210.
    https://doi.org/10.1002/acr.24459
  20. Sepriano, Alexandre; Ramiro, Sofia; Landewé, Robert; Moltó, Anna; Claudepierre, Pascal; Wendling, Daniel; Dougados, Maxime; van der Heijde, Désirée. "Inflammation of the sacroiliac joints and spine on MRI predicts structural changes on MRI in axial spondyloarthritis". (2022): http://hdl.handle.net/10362/131251.
    https://doi.org/10.1002/acr.24449
  21. Victoria Navarro-Compán; Alexandre Sepriano; Bassel El-Zorkany; Désirée van der Heijde. "Axial spondyloarthritis". Annals of the Rheumatic Diseases 80 12 (2021): 1511-1521. https://doi.org/10.1136/annrheumdis-2021-221035.
    10.1136/annrheumdis-2021-221035
  22. Alunno A; Rivellese F; Lauper K; Aletaha D; Buch MH; Gossec L; Mandl P; et al. "EMerging EULAR NETwork (EMEUNET): a remarkable foundation for the future.". RMD open (2021): http://europepmc.org/abstract/med/34969822.
    10.1136/rmdopen-2021-001962
  23. Neto A; Pinheiro Torres R; Ramiro S; Sardoo A; Rodrigues-Manica S; Lagoas-Gomes J; Domingues L; et al. "Muscle dysfunction in axial spondylarthritis: the MyoSpA study.". Clinical and experimental rheumatology (2021): http://europepmc.org/abstract/med/34874829.
    10.55563/clinexprheumatol/9ljng7
  24. Sardoo AM; Neto A; Pinheiro Torres R; Rodrigues-Manica S; Domingues L; Lage Crespo C; Lagoas-Gomes J; et al. "The role of muscle in the susceptibility and progression of axial Spondyloarthritis: The MyoSpA Study Protocol.". Acta reumatologica portuguesa (2021): http://europepmc.org/abstract/med/34962249.
  25. Alexandre Sepriano; Sofia Ramiro; Stephanie Wichuk; Praveena Chiowchanwisawakit; Joel Paschke; Désirée Heijde; Robert Landewé; Walter P. Maksymowych. "Tumor Necrosis Factor Inhibitors Reduce Spinal Radiographic Progression in Patients With Radiographic Axial Spondyloarthritis: A Longitudinal Analysis From the Alberta Prospective Cohort". Arthritis & Rheumatology 73 7 (2021): 1211-1219. https://doi.org/10.1002/art.41667.
    10.1002/art.41667
  26. Alexandre Sepriano; Sofia Ramiro; Desirée van der Heijde; Robert Landewé. "Biological DMARDs and disease modification in axial spondyloarthritis: a review through the lens of causal inference". RMD Open (2021): https://doi.org/10.1136/rmdopen-2021-001654.
    10.1136/rmdopen-2021-001654
  27. Cruz M; Rodrigues AM; Dias S; Sepriano A; Canhão H; Gouveia N; Ramiro S; Branco JC. "Obesity and diabetes are associated with disability in women with hand osteoarthritis. Results from the EpiReumaPt nationwide study.". Acta reumatologica portuguesa (2021): http://europepmc.org/abstract/med/34626463.
  28. Mikhail Protopopov; Fabian Proft; Alexandre Sepriano; Robert Landewé; Désirée van der Heijde; Walter P Maksymowych; Xenofon Baraliakos; et al. "Radiographic sacroiliitis progression in axial spondyloarthritis: central reading of 5 year follow-up data from the Assessment of SpondyloArthritis international Society cohort". Rheumatology 60 5 (2021): 2478-2480. https://doi.org/10.1093/rheumatology/keab091.
    10.1093/rheumatology/keab091
  29. Pimentel-Santos F; Rodrigues Manica S; Masi AT; Lagoas-Gomes J; Santos MB; Ramiro S; Sepriano A; et al. "Lumbar myofascial physical properties in healthy adults: myotonometry vs. shear wave elastography measurements.". Acta reumatologica portuguesa (2021): http://europepmc.org/abstract/med/34226434.
  30. Alexandre Sepriano; Sofia Ramiro; Stephanie Wichuk; Praveena Chiowchanwisawakit; Joel Paschke; Désirée van der Heijde; Robert Landewé; Walter P. Maksymowych. "Disease activity is associated with spinal radiographic progression in axial spondyloarthritis independently of exposure to tumour necrosis factor inhibitors". Rheumatology (2021): https://doi.org/10.1093/rheumatology/keaa564.
    10.1093/rheumatology/keaa564
  31. Stal, R.; Sepriano, A.; Van Gaalen, F. A.; Baraliakos, X.; Van den Berg, R.; Reijnierse, M.; Braun, J.; Landewe, R. B. M.; Van der Heijde, D.. "IN RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS, BRIDGING SYNDESMOPHYTES INCREASE RISK OF FACET JOINT ANKYLOSIS ON THE SAME VERTEBRAL LEVEL WHILE FACET JOINT ANKYLOSIS DOES NOT INCREASE RISK OF SAME LEVEL SYNDESMOPHYTES". Annals of the Rheumatic Diseases (2021): https://publons.com/wos-op/publon/50239084/.
    10.1136/ANNRHEUMDIS-2021-EULAR.1097
  32. Stal, R.; Baraliakos, X.; Sepriano, A.; Van Gaalen, F. A.; Ramiro, S.; Van den Berg, R.; Reijnierse, M.; et al. "MRI VERTEBRAL CORNER INFLAMMATION AND FAT DEPOSITION ARE ASSOCIATED WITH WHOLE SPINE LOW DOSE CT DETECTED SYNDESMOPHYTES: A MULTILEVEL ANALYSIS". Annals of the Rheumatic Diseases (2021): https://publons.com/wos-op/publon/50239083/.
    10.1136/ANNRHEUMDIS-2021-EULAR.1337
  33. De Hooge, M.; Hanlon, M.; Alunno, A.; Sepriano, A.; Lauper, K.; Rivellese, F.. "THE EMERGING EULAR NETWORK (EMEUNET): AN INTERNATIONAL SURVEY REFLECTING ON A TEN-YEAR JOURNEY". Annals of the Rheumatic Diseases (2021): https://publons.com/wos-op/publon/50140538/.
    10.1136/ANNRHEUMDIS-2021-EULAR.2706
  34. Sepriano, Alexandre; Ramiro, Sofia; Wichuk, Stephanie; Chiowchanwisawakit, Praveena; Paschke, Joel; van der Heijde, Désirée; Landewé, Robert; Maksymowych, Walter P. "TNF inhibitors reduce spinal radiographic progression in patients with radiographic axial spondyloarthritis". (2021): http://hdl.handle.net/10362/135560.
    https://doi.org/10.1002/art.41667
  35. Rosalinde Stal; Floris van Gaalen; Alexandre Sepriano; Juergen Braun; Monique Reijnierse; Rosaline van den Berg; Désirée van der Heijde; Xenofon Baraliakos. "Facet joint ankylosis in r-axSpA: detection and 2-year progression on whole spine low-dose CT and comparison with syndesmophyte progression". Rheumatology (2020): https://doi.org/10.1093/rheumatology/keaa155.
    10.1093/rheumatology/keaa155
  36. Augusta Ortolan; Victoria Navarro-Compán; Alexandre Sepriano; Robert B M Landewé; Désirée van der Heijde; Sofia Ramiro. "Which disease activity outcome measure discriminates best in axial spondyloarthritis? A systematic literature review and meta-analysis". Rheumatology (2020): https://doi.org/10.1093/rheumatology/keaa527.
    10.1093/rheumatology/keaa527
  37. Alexandre Sepriano; Sofia Ramiro; Désirée van der Heijde; Maxime Dougados; Pascal Claudepierre; Antoine Feydy; Monique Reijnierse; Damien Loeuille; Robert Landewé. "Integrated longitudinal analysis does not compromise precision and reduces bias in the study of imaging outcomes: A comparative 5-year analysis in the DESIR cohort". Seminars in Arthritis and Rheumatism 50 6 (2020): 1394-1399. https://doi.org/10.1016/j.semarthrit.2020.02.017.
    10.1016/j.semarthrit.2020.02.017
  38. Elena Nikiphorou; Sofia Ramiro; Alexandre Sepriano; Adeline Ruyssen-Witrand; Robert B. M. Landewé; Désirée Heijde. "Do Smoking and Socioeconomic Factors Influence Imaging Outcomes in Axial Spondyloarthritis? Five-Year Data From the DESIR Cohort". Arthritis & Rheumatology 72 11 (2020): 1855-1862. https://doi.org/10.1002/art.41408.
    10.1002/art.41408
  39. Alexandre Sepriano; Sofia Ramiro; Robert Landewé; Anna Moltó; Pascal Claudepierre; Daniel Wendling; Maxime Dougados; Désirée van der Heijde. "Inflammation of the sacroiliac joints and spine on MRI predicts structural changes on MRI in axial spondyloarthritis: 5-year data from DESIR". Arthritis Care & Research (2020): https://doi.org/10.1002/acr.24449.
    10.1002/acr.24449
  40. Najm A; Kostine M; Pauling JD; Ferreira AC; Stevens K; Smith E; Eguiluz-Gracia I; et al. "Multidisciplinary collaboration among young specialists: results of an international survey by the emerging EULAR network and other young organisations.". RMD open (2020): http://europepmc.org/abstract/med/32934010.
    10.1136/rmdopen-2020-001398
  41. Lennart van der Burg; Alexandre Sepriano; Robert Landewé; Goedele Geuskens; Ramon Ottenheijm; Geert-Jan Dinant; Annelies Boonen. "Comparative construct validity of three presenteeism instruments in workers with musculoskeletal complaints: a prospective cohort study". RMD Open (2020): https://doi.org/10.1136/rmdopen-2020-001281.
    10.1136/rmdopen-2020-001281
  42. Manica SR; Sepriano A; Pimentel-Santos F; Gouveia N; Barcelos A; Branco JC; Bernardes M; et al. "Effectiveness of switching between TNF inhibitors in patients with axial spondyloarthritis: is the reason to switch relevant?". Arthritis research & therapy (2020): http://europepmc.org/abstract/med/32825839.
    10.1186/s13075-020-02288-8
  43. Josef S Smolen; Robert B M Landewé; Johannes W J Bijlsma; Gerd R Burmester; Maxime Dougados; Andreas Kerschbaumer; Iain B McInnes; et al. "EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update". Annals of the Rheumatic Diseases (2020): annrheumdis--2019--2-annrheumdis--2019--2. https://doi.org/10.1136/annrheumdis-2019-216655.
    10.1136/annrheumdis-2019-216655
  44. Andreas Kerschbaumer; Alexandre Sepriano; Josef S Smolen; Désirée van der Heijde; Maxime Dougados; Ronald van Vollenhoven; Iain B McInnes; et al. "Efficacy of pharmacological treatment in rheumatoid arthritis: a systematic literature research informing the 2019 update of the EULAR recommendations for management of rheumatoid arthritis". Annals of the Rheumatic Diseases (2020): annrheumdis--2019--2-annrheumdis--2019--2. https://doi.org/10.1136/annrheumdis-2019-216656.
    10.1136/annrheumdis-2019-216656
  45. Alexandre Sepriano; Andreas Kerschbaumer; Josef S Smolen; Désirée van der Heijde; Maxime Dougados; Ronald van Vollenhoven; Iain B McInnes; et al. "Safety of synthetic and biological DMARDs: a systematic literature review informing the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis". Annals of the Rheumatic Diseases 79 6 (2020): 760-770. https://doi.org/10.1136/annrheumdis-2019-216653.
    10.1136/annrheumdis-2019-216653
  46. Alexandre Sepriano; Sofia Ramiro; Oliver FitzGerald; Mikkel Østergaard; Joanne Homik; Désirée van der Heijde; Ori Elkayam; et al. "Adherence to Treat-to-target Management in Rheumatoid Arthritis and Associated Factors: Data from the International RA BIODAM Cohort". The Journal of Rheumatology (2020): jrheum.190303-jrheum.190303. https://doi.org/10.3899/jrheum.190303.
    10.3899/jrheum.190303
  47. Sofia Ramiro; Robert BM Landewé; Désirée van der Heijde; Alexandre Sepriano; Oliver FitzGerald; Mikkel Ostergaard; Joanne Homik; et al. "Is treat-to-target really working in rheumatoid arthritis? a longitudinal analysis of a cohort of patients treated in daily practice (RA BIODAM)". Annals of the Rheumatic Diseases 79 4 (2020): 453-459. https://doi.org/10.1136/annrheumdis-2019-216819.
    10.1136/annrheumdis-2019-216819
  48. Alexandre Sepriano; Sofia Ramiro; Désirée van der Heijde; Robert B M Landewé. "Response to: ‘Reactive arthritis, a missing link: comment on the recent article from Sepriano et al’ by Zeidler and Hudson". Annals of the Rheumatic Diseases (2020): annrheumdis--2020--2-annrheumdis--2020--2. https://doi.org/10.1136/annrheumdis-2020-217347.
    10.1136/annrheumdis-2020-217347
  49. Alexandre Sepriano; Sofia Ramiro; Désirée van der Heijde; Floris van Gaalen; Pierre Hoonhout; Anna Molto; Alain Saraux; et al. "What is axial spondyloarthritis? A latent class and transition analysis in the SPACE and DESIR cohorts". Annals of the Rheumatic Diseases 79 3 (2020): 324-331. https://doi.org/10.1136/annrheumdis-2019-216516.
    10.1136/annrheumdis-2019-216516
  50. Javier Rodríguez-Carrio; Polina Putrik; James Gwinnut; Alexandre Sepriano; Alessia Alunno; Sofia Ramiro; Jan Leipe; Elena Nikiphorou. "Mentoring for postdoctoral researchers in rheumatology: the Emerging EULAR Network (EMEUNET) post-doc mentoring programme". RMD Open (2020): https://doi.org/10.1136/rmdopen-2019-001139.
    10.1136/rmdopen-2019-001139
  51. Jose Marona; Alexandre Sepriano; Santiago Rodrigues-Manica; Fernando Pimentel-Santos; Ana Filipa Mourão; Nélia Gouveia; Jaime Cunha Branco; et al. "Eligibility criteria for biologic disease-modifying antirheumatic drugs in axial spondyloarthritis: going beyond BASDAI". RMD Open (2020): https://doi.org/10.1136/rmdopen-2019-001145.
    10.1136/rmdopen-2019-001145
  52. Rodrigues-Manica S; Cruz E; Ramiro S; Sousa S; Aguiar R; Sepriano A; Machado P; et al. "The European Portuguese version of the ASAS Health Index for Patients with Spondyloarthritis: Measurement properties.". Acta reumatologica portuguesa (2020): http://europepmc.org/abstract/med/32572012.
  53. Rodríguez-Carrio, Javier; Putrik, Polina; Gwinnut, James; Sepriano, Alexandre; Alunno, Alessia; Ramiro, Sofia; Leipe, Jan; Nikiphorou, Elena. "Mentoring for postdoctoral researchers in rheumatology". (2020): http://hdl.handle.net/10362/92990.
    https://doi.org/10.1136/rmdopen-2019-001139
  54. Madari, Queeny; Sepriano, Alexandre; Ramiro, Sofia; Molto, Anna; Claudepierre, Pascal; Wendling, Daniel; Dougados, Maxime; et al. "5-year follow-up of spinal and sacroiliac MRI abnormalities in early axial spondyloarthritis". RMD Open (2020): http://hdl.handle.net/10362/92991.
    https://doi.org/10.1136/rmdopen-2019-001093
  55. Najm, Aurélie; Kostine, Marie; Pauling, John D.; Ferreira, Ana Carina; Stevens, Kate; Smith, Evelyn; Eguiluz-Gracia, Ibon; et al. "Multidisciplinary collaboration among young specialists". (2020): http://hdl.handle.net/10362/104688.
    https://doi.org/10.1136/rmdopen-2020-001398
  56. Niels W Boone; Alexandre Sepriano; Paul-Hugo van der Kuy; Rob Janknegt; Ralph Peeters; Robert B M Landewé. "Routine Assessment of Patient Index Data 3 (RAPID3) alone is insufficient to monitor disease activity in rheumatoid arthritis in clinical practice". RMD Open 5 2 (2019): e001050-e001050. https://doi.org/10.1136/rmdopen-2019-001050.
    10.1136/rmdopen-2019-001050
  57. Ramiro S; van der Heijde D; Sepriano A; van Lunteren M; Moltó A; Feydy A; d'Agostino MA; et al. "Spinal Radiographic Progression in Early Axial Spondyloarthritis: Five-Year Results From the DESIR Cohort.". Arthritis care & research (2019): http://europepmc.org/abstract/med/30354022.
    10.1002/acr.23796
  58. Miranda van Lunteren; Désirée van der Heijde; Alexandre Sepriano; Inger J Berg; Maxime Dougados; Laure Gossec; Lennart Jacobsson; et al. "Is a positive family history of spondyloarthritis relevant for diagnosing axial spondyloarthritis once HLA-B27 status is known?". Rheumatology 58 9 (2019): 1649-1654. https://doi.org/10.1093/rheumatology/kez095.
    10.1093/rheumatology/kez095
  59. Maksymowych WP; FitzGerald O; Østergaard M; Homik J; van der Heijde D; Lambert RG; Elkayam O; et al. "Outcomes and Findings of the International Rheumatoid Arthritis (RA) BIODAM Cohort for Validation of Soluble Biomarkers in RA.". The Journal of rheumatology (2019): http://europepmc.org/abstract/med/31474600.
    10.3899/jrheum.190302
  60. Alexandre Rocha Sepriano; Sofia Ramiro; Filipe C Araújo; Pedro M Machado; Ana M Rodrigues; Nélia Gouveia; Mónica Eusébio; Helena Canhão; Jaime Branco. "Performance of referral strategies for spondyloarthritis: a population-based nationwide study". Rheumatology (2019): https://doi.org/10.1093/rheumatology/key436.
    10.1093/rheumatology/key436
  61. Sytske Anne Bergstra; Alexandre Sepriano; Sofia Ramiro; Robert Landewé. "Three handy tips and a practical guide to improve your propensity score models". RMD Open 5 1 (2019): e000953-e000953. https://doi.org/10.1136/rmdopen-2019-000953.
    10.1136/rmdopen-2019-000953
  62. Alexandre Sepriano; Sofia Ramiro; Robert Landewé; Maxime Dougados; Desirée van der Heijde. "Percentage of progressors in imaging: can we ignore regressors?". RMD Open 5 1 (2019): e000848-e000848. https://doi.org/10.1136/rmdopen-2018-000848.
    10.1136/rmdopen-2018-000848
  63. Niels W. Boone; Alexandre Sepriano; Paul-Hugo van der Kuy; Rob Janknegt; Ralph Peeters; Robert B. M. Landewé. "Cotreatment with methotrexate in routine care patients with rheumatoid arthritis receiving biological treatment yields better outcomes over time". RMD Open 5 1 (2019): e000836-e000836. https://doi.org/10.1136/rmdopen-2018-000836.
    10.1136/rmdopen-2018-000836
  64. Gomes JL; Sepriano A; Eusébio M; Serra S; Fonseca JE; Saavedra MJ; Cunha-Miranda L; et al. "Predictors and causes of first-line biologic agent discontinuation in rheumatoid arthritis: data from Reuma.pt.". Acta reumatologica portuguesa 44 1 (2019): 57-64. http://europepmc.org/abstract/med/31249276.
  65. Sepriano, A.; Ramiro, S.; Landewé, R.; Dougados, M.; Van Der Heijde, D.; Rudwaleit, M.. "Is active sacroiliitis on MRI associated with radiographic damage in axial spondyloarthritis? Real-life data from the ASAS and DESIR cohorts". Rheumatology (United Kingdom) 58 5 (2019): 798-802. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067702134&partnerID=MN8TOARS.
    10.1093/rheumatology/key387
  66. Ramiro, Sofia; van der Heijde, Désirée; Sepriano, Alexandre; van Lunteren, Miranda; Moltó, Anna; Feydy, Antoine; d'Agostino, Maria Antonietta; et al. "Spinal Radiographic Progression in Early Axial Spondyloarthritis". (2019): http://hdl.handle.net/10362/147413.
    https://doi.org/10.1002/acr.23796
  67. Ferreira-Dos-Santos, Guilherme; Domingues, Lúcia; Sepriano, Alexandre; Mourão, Ana Filipa; Silveira Botelho, Maria Amália; Pereira, Carla Sandra.; Espino, Carlos Lodeiro; et al. "Tools for the Screening of Sarcopenia: A Head-to-Head Comparison by the NOVA SarcoAging Group". Archives of Physical Medicine and Rehabilitation 99 10 (2018): e110. http://dx.doi.org/10.1016/j.apmr.2018.07.393.
    10.1016/j.apmr.2018.07.393
  68. Santiago Rodrigues Manica; Alexandre Sepriano; Sofia Ramiro; Fernando Pimentel Santos; Polina Putrik; Elena Nikiphorou; Sam Norton; et al. "Work participation in spondyloarthritis across countries: analysis from the ASAS-COMOSPA study". Annals of the Rheumatic Diseases 77 9 (2018): 1303-1310. https://doi.org/10.1136/annrheumdis-2018-213464.
    10.1136/annrheumdis-2018-213464
  69. van Lunteren M; Sepriano A; Landewé R; Sieper J; Rudwaleit M; van der Heijde D; van Gaalen F. "Do ethnicity, degree of family relationship, and the spondyloarthritis subtype in affected relatives influence the association between a positive family history for spondyloarthritis and HLA-B27 carriership? Results from the worldwide ASAS cohort.". Arthritis research & therapy (2018): http://europepmc.org/abstract/med/30075809.
    10.1186/s13075-018-1672-2
  70. Stamm TA; Machold KP; Aletaha D; Alasti F; Lipsky P; Pisetsky D; Landewe R; et al. "Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial.". Arthritis research & therapy (2018): http://europepmc.org/abstract/med/30092827.
    10.1186/s13075-018-1667-z
  71. Ramiro S; Claudepierre P; Sepriano A; van Lunteren M; Molto A; Feydy A; Antonietta d'Agostino M; et al. "Which scoring method depicts spinal radiographic damage in early axial spondyloarthritis best? Five-year results from the DESIR cohort.". Rheumatology (Oxford, England) (2018): http://europepmc.org/abstract/med/30053219.
    10.1093/rheumatology/key185
  72. Duftner C; Dejaco C; Sepriano A; Falzon L; Schmidt WA; Ramiro S. "Imaging in diagnosis, outcome prediction and monitoring of large vessel vasculitis: a systematic literature review and meta-analysis informing the EULAR recommendations.". RMD open (2018): http://europepmc.org/abstract/med/29531788.
    10.1136/rmdopen-2017-000612
  73. Machado, P.M.; Cerqueira, M.; Ávila-Ribeiro, P.; Aguiar, R.; Bernardo, A.; Sepriano, A.; Águeda, A.; et al. "Portuguese recommendations for the use of biological therapies in patients with axial spondyloarthritis - 2016 update". Acta Reumatologica Portuguesa 2018 1 (2018): 52-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042560361&partnerID=MN8TOARS.
  74. Araújo, F.C.; Sepriano, A.; Teixeira, F.; Jesus, D.; Rocha, T.M.; Martins, P.; Tenazinha, C.; et al. "The Portuguese Society of Rheumatology position paper on the use of biosimilars - 2017 update". Acta Reumatologica Portuguesa 2018 1 (2018): 62-71. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042565771&partnerID=MN8TOARS.
  75. Rodríguez-Carrio, Javier; Putrik, Polina; Sepriano, Alexandre; Moltó, Anna; Nikiphorou, Elena; Gossec, Laure; Kvien, Tore K; et al. "Improving the peer review skills of young rheumatologists and researchers in rheumatology". RMD Open (2018): http://hdl.handle.net/10362/32939.
    https://doi.org/10.1136/rmdopen-2017-000619
  76. Maxime Dougados; Alexandre Sepriano; Anna Molto; Miranda van Lunteren; Sofia Ramiro; Manouk de Hooge; Rosaline van den Berg; et al. "Sacroiliac radiographic progression in recent onset axial spondyloarthritis: the 5-year data of the DESIR cohort". Annals of the Rheumatic Diseases 76 11 (2017): 1823-1828. https://doi.org/10.1136/annrheumdis-2017-211596.
    10.1136/annrheumdis-2017-211596
  77. Cruz EB; Ramiro S; Machado P; Sousa S; Aguiar R; Sepriano A; Manica SR; et al. "Translation and cross-cultural adaptation of the ASAS Health Index and ASAS Environmental Factors Item Set into European Portuguese Language.". Acta reumatologica portuguesa (2017): http://europepmc.org/abstract/med/28860446.
  78. Araújo FC; Sepriano A; Teixeira F; Jesus D; Rocha TM; Martins P; Tenazinha C; et al. "The Portuguese Society of Rheumatology position paper on the use of biosimilars - 2017 update.". Acta reumatologica portuguesa (2017): http://europepmc.org/abstract/med/28894080.
  79. Sofia Ramiro; Alexandre Sepriano; Katerina Chatzidionysiou; Jackie L Nam; Josef S Smolen; Désirée van der Heijde; Maxime Dougados; et al. "Safety of synthetic and biological DMARDs: a systematic literature review informing the 2016 update of the EULAR recommendations for management of rheumatoid arthritis". Annals of the Rheumatic Diseases 76 6 (2017): 1101-1136. https://doi.org/10.1136/annrheumdis-2016-210708.
    10.1136/annrheumdis-2016-210708
  80. Désirée van der Heijde; Sofia Ramiro; Robert Landewé; Xenofon Baraliakos; Filip Van den Bosch; Alexandre Sepriano; Andrea Regel; et al. "2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis". Annals of the Rheumatic Diseases 76 6 (2017): 978-991. https://doi.org/10.1136/annrheumdis-2016-210770.
    10.1136/annrheumdis-2016-210770
  81. Alexandre Sepriano; Roxana Rubio; Sofia Ramiro; Robert Landewé; Désirée van der Heijde. "Performance of the ASAS classification criteria for axial and peripheral spondyloarthritis: a systematic literature review and meta-analysis". Annals of the Rheumatic Diseases 76 5 (2017): 886-890. https://doi.org/10.1136/annrheumdis-2016-210747.
    10.1136/annrheumdis-2016-210747
  82. Andrea Regel; Alexandre Sepriano; Xenofon Baraliakos; Désirée van der Heijde; Jürgen Braun; Robert Landewé; Filip Van den Bosch; Louise Falzon; Sofia Ramiro. "Efficacy and safety of non-pharmacological and non-biological pharmacological treatment: a systematic literature review informing the 2016 update of the ASAS/EULAR recommendations for the management of axial spondyloarthritis". RMD Open (2017):
    10.1136/rmdopen-2016-000397
  83. Alexandre Sepriano; Andrea Regel; Désirée van der Heijde; Jürgen Braun; Xenofon Baraliakos; Robert Landewé; Filip Van den Bosch; Louise Falzon; Sofia Ramiro. "Efficacy and safety of biological and targeted-synthetic DMARDs: a systematic literature review informing the 2016 update of the ASAS/EULAR recommendations for the management of axial spondyloarthritis". RMD Open (2017):
    10.1136/rmdopen-2016-000396
  84. Dougados, Maxime; Sepriano, Alexandre; Molto, Anna; Van Lunteren, Miranda; Ramiro, Sofia; De Hooge, Manouk; Van Den Berg, Rosaline; et al. "Sacroiliac radiographic progression in recent onset axial spondyloarthritis". (2017): http://hdl.handle.net/10362/149629.
    https://doi.org/10.1136/annrheumdis-2017-211596
  85. Sepriano A; Ramiro S; van der Heijde D; Ávila-Ribeiro P; Fonseca R; Borges J; Teixeira L; et al. "Effect of comedication with conventional synthetic DMARDs on TNF inhibitors-retention in patients with spondyloarthritis: A prospective cohort.". (2016): http://europepmc.org/abstract/med/27273894.
    10.1002/art.39772
  86. Sepriano A; Rudwaleit M; Sieper J; van den Berg R; Landewé R; van der Heijde D. "Five-year follow-up of radiographic sacroiliitis: progression as well as improvement?". (2016): http://europepmc.org/abstract/med/26903442.
    10.1136/annrheumdis-2015-208964
  87. Sepriano A; Landewé R; van der Heijde D; Sieper J; Akkoc N; Brandt J; Braun J; et al. "Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis.". (2016): http://europepmc.org/abstract/med/26865599.
    10.1136/annrheumdis-2015-208730
  88. Vieira Sousa E; Sepriano A; Pimentel Santos F. "Investigator initiated trials in Portuguese rheumatology.". (2016): http://europepmc.org/abstract/med/27606469.
  89. Branco JC; Rodrigues AM; Gouveia N; Eusébio M; Ramiro S; Machado PM; da Costa LP; et al. "Prevalence of rheumatic and musculoskeletal diseases and their impact on health-related quality of life, physical function and mental health in Portugal: results from EpiReumaPt- a national health survey.". (2016): http://europepmc.org/abstract/med/26848402.
    10.1136/rmdopen-2015-000166
  90. Molto, A.; Ramiro, S.; Landewé, R.; Xenofon, B.; Van den bosch, F.; Sepriano, A.; Regel, A.; et al. "Recommandations ASAS-EULAR 2016 pour la prise en charge des Spondyloarthrites axiales". Revue du Rhumatisme (Edition Francaise) 83 (2016): A117-A117. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007566463&partnerID=MN8TOARS.
    10.1016/S1169-8330(16)30386-6
  91. Alexandre Sepriano; Jorge A. Roman-Blas; Robert D. Little; Fernando Pimentel-Santos; Jose María Arribas; Raquel Largo; Jaime C. Branco; Gabriel Herrero-Beaumont. "DXA in the assessment of subchondral bone mineral density in knee osteoarthritis—A semi-standardized protocol after systematic review". Seminars in Arthritis and Rheumatism 45 3 (2015): 275-283. http://dx.doi.org/10.1016/j.semarthrit.2015.06.012.
    10.1016/j.semarthrit.2015.06.012
  92. Rodrigues AM; Gouveia N; da Costa LP; Eusébio M; Ramiro S; Machado P; Mourão AF; et al. "EpiReumaPt- the study of rheumatic and musculoskeletal diseases in Portugal: a detailed view of the methodology.". Acta reumatologica portuguesa (2015): http://europepmc.org/abstract/med/26219965.
  93. Araújo F; Silva I; Sepriano A; Reizinho C; Marques L; Nero P; Branco JC. "Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report.". Acta reumatologica portuguesa (2015): http://europepmc.org/abstract/med/24861079.
  94. Sepriano AR; Pereira Pombo de Araújo FC; Mourão de Almeida Lourenço Dias PM; da Cunha Branco J. "Normocalcemic primary hyperparathyroidism presenting as calcinosis cutis.". (2014): http://europepmc.org/abstract/med/25160019.
    10.1097/RHU.0000000000000142
  95. Fonseca JE; Gonçalves J; Araújo F; Cordeiro I; Teixeira F; Canhão H; da Silva JA; et al. "The Portuguese Society of Rheumatology position paper on the use of biosimilars.". Acta reumatologica portuguesa (2014): http://europepmc.org/abstract/med/24811463.
  96. Araújo F; Silva I; Sepriano A; Nero P; Branco JC. "Off-label use of rituximab in systemic rheumatic diseases: case series and review.". Acta reumatologica portuguesa (2013): http://europepmc.org/abstract/med/24435034.
  97. Rodrigues AM; Caetano-Lopes J; Vale AC; Vidal B; Lopes A; Aleixo I; Polido-Pereira J; et al. "Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures.". (2012): http://europepmc.org/abstract/med/22975110.
    10.1016/j.bone.2012.08.129
  98. Rodrigues AM; Caetano-Lopes J; Vale AC; Aleixo I; Pena AS; Faustino A; Sepriano A; et al. "Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients.". (2012): http://europepmc.org/abstract/med/22886402.
    10.1007/s00774-012-0370-4
  99. Machado, P.; Bogas, M.; Ribeiro, A.; Costa, J.; Neto, A.; Sepriano, A.; Raposo, A.; et al. "2011 Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis". Acta Reumatologica Portuguesa 37 1 (2012): 26-39. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862996511&partnerID=MN8TOARS.
  100. Rodrigues A; Caetano-Lopes J; Lopes A; Vale AC; Aleixo I; Perpétuo IP; Pena AS; et al. "Apolipoprotein E and undercaboxylated osteocalcin are associated with bone fragility but not with bone mineral density in osteoarthritis patients.". (2011): http://europepmc.org/abstract/PMC/PMC3242284.
Resumo em conferência
  1. Chícharo, Ana Teodósio; Santos, Mariana Emília; Lucas Rocha, Margarida; Gago, Laura; Lourenço, Maria Helena; Bento da Silva, Ana; Sepriano, Alexandre; et al. Autor correspondente: Chícharo, Ana Teodósio. "Úlceras cutâneas na artrite reumatoide – o que não esquecer". Trabalho apresentado em XXIV Congresso Português de Reumatologia, Albufeira, 2022.
    Publicado
  2. Rodrigues-Manica, Santiago; Sepriano, Alexandre; F. M. Pimentel-Santos; Gouveia, Nélia; Barcelos, A; Branco, J; Bernardes, M; et al. "AB 1500 Effectiveness of Switching Between TNF Inhibitors in Patients with Axial Spondyloarthritis: Is the Reason to Switch Relevant?". Trabalho apresentado em 2019 ACR/ARP Annual Meeting, 2019.
    Publicado
Distinções

Prémio

2019 Best oral communication (honorable mention, first author)
Sociedade Portuguesa de Reumatologia, Portugal
2018 Best original work presented as a poster (first author)
Sociedade Portuguesa de Reumatologia, Portugal
2016 Bial Prize of Medicine 2016 (co-author)
Fundação Bial, Portugal
2013 Best Clinical Poster (first author)
Sociedade Portuguesa de Reumatologia, Portugal

Título

2020 PhD Cum Laude
Leids Universitair Medisch Centrum, Países Baixos