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Catarina Neves graduated in Biology at the Faculty of Science and Technology of the University of Coimbra in 2013, and obtained her Master (Biomedical Research Master - MIB) at the Faculty of Medicine of the University of Coimbra in 2015. In parallel with her Master thesis "The impact of elevated hydrostatic pressure in microglia: changes in the adenosinergic system and inflammatory responses" at the Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, she was involved in two funded projects: 1) "From neuroinflammation control to neuroprotection: blocking adenosine A2A receptor for the treatment of glaucoma", supported by FCT, and 2) "Managing inflammation in diabetic retinopathy by adenosine A2A receptor blockade", supported by Bayer. Within these projects, she participated in national and international scientific meetings (3 oral communications and 7 posters) and was author/co-author of 4 original and 1 review manuscripts. In 2016, she became a research fellow of the project "The changing brain in Alzheimer's disease (AD): is the retina a reliable mirror of disease onset and progression?", supported by Santa Casa da Misericórdia de Lisboa. As part of this project, she participated in national and international scientific meetings (1 international oral communication and 9 posters) and was author/co-author of 3 original and 1 review manuscripts. In 2019, she received an individual Ph.D. fellowship from FCT and started her Ph.D. "The putative role of microglia in schizophrenia gender differences" in Pharmaceutical Sciences at the Faculty of Pharmacy, University of Coimbra. As part of this project, she participated in national and international scientific meetings (5 oral communications and 10 posters) and published 1 review article and 1 original article (another one prepared for submission). During this time, Catarina also gave some theoretical courses (2017-2022). Overall, Catarina is author/co-author of 12 publications, 20 oral communications and 30 posters.
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Identificação

Identificação pessoal

Nome completo
Ana Catarina Rodrigues Neves

Nomes de citação

  • Rodrigues-Neves AC

Identificadores de autor

Ciência ID
4F10-888E-7CA9
ORCID iD
0000-0003-3290-9238

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
2019/07/01 - 2023/06/30
Em curso
 Doutoramento em Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2015/09/11
Concluído
 Mestrado em Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"The impact of elevated hydrostatic pressure in microglia: changes in the adenosinergic system and inflammatory responses" (TESE/DISSERTAÇÃO)
 17
2013/07/02
Concluído
 Biologia (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"---" (TESE/DISSERTAÇÃO)
 14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/04/03 - 2017/04/07 Estagiário de Investigação (Investigação) Universidad Complutense de Madrid, Espanha
2014/04 - 2014/04 Estagiário de Investigação (Investigação) Center for Neurosciences and Cell Biology – UC Biotech, Cantanhede , Portugal
2014/03 - 2014/03 Estagiário de Investigação (Investigação) Coimbra Institute for Clinical and Biomedical Research (iCBR), Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2019/07/01 - 2023 PhD student Faculdade de Farmácia da Universidade do Coimbra, Portugal
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2021/12 - 2022/03 Visiting PhD student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal, Portugal
2020/03 - 2020/05 Volunteer technician (COVID-19 PCR-tests) at Clinical Analysis Laboratory of the University of Coimbra, Coimbra, Portugal Laboratório de análises clínicas da Universidade de Coimbra, Portugal
2020/02 - 2020/02 Volunteer Staff at XL Annual meeting of Portuguese Society for Pharmacology (SPF), XXXVIII Clinic Pharmacology meeting, XIX Toxicology, Coimbra, Portugal. Faculdade de Farmácia da Universidade do Coimbra, Portugal
2019/10 - 2019/11 Visiting PhD student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/07 - 2019/07 Volunteer Staff at XIV European Meeting on Glial Cells in Health and Disease Instituto de Biologia Molecular e Celular, Portugal
2016/05/01 - 2019/06/30 Researcher fellow of the project "The changing brain in Alzheimer's disease: is the retina a reliable mirror of disease onset and progression?" (Mantero Belard 2015) Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2013/11/01 - 2015/09/11 MSc in Biomedical Research Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2009/09/01 - 2013/09/02 BSc degree in Biology Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/11/01 - 2013/02/01 Volunteer internship Center of Neuroscience and Cell Biology, Portugal
Projetos

Bolsa

Designação Financiadores
2019/07/01 - 2023/06/30 Putative role of microglia dimorphism in schizophrenia gender differences
SFRH/BD/141754/2018
Bolseiro de Doutoramento
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso

Projeto

Designação Financiadores
2023 - 2026 Deciphering the role of Piezo1 mechanosensitive channel in microglia-mediated glaucomatous neurodegeneration
2022.01354.PTDC
Investigador
Coimbra Institute for Clinical and Biomedical Research (iCBR), Portugal
Em curso
2021 - 2023 Mitochondria as potential drivers of sex-specific microglia dysfunctional remodeling and anxiety caused by prenatal stress
EXPL/MED-NEU/1002/2021
Desenvolvimento técnico
Coimbra Institute for Clinical and Biomedical Research (iCBR), Portugal
Concluído
2019 - 2020 Predictors of resistance to corticotherapy in children with nephrotic syndrome
FMUC-BST-2019
Desenvolvimento técnico
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
 Faculty of Medicina of Coimbra, University of Coimbra with finantial support of Santader Totta bank
Em curso
2016/05/18 - 2018/11/17 The changing brain in Alzheimer's disease: is the retina a reliable mirror of disease onset and progression?
MB-1049-2015
Bolseiro de Técnico de Investigação
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
 Santa Casa da Misericórdia de Lisboa
Concluído
2015/12 - 2016/11 Managing inflammation in diabetic retinopathy by adenosine A2A receptor blockade
US2083156314
Desenvolvimento técnico
Bayer Animal Health GmbH
Concluído
2013/06/01 - 2015/12 From neuroinflammation control to neuroprotection: blocking adenosine A2A receptor for the treatment of glaucoma
PTDC/BIM-MEC/0913/2012
Desenvolvimento técnico
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Simões-Henriques C.F.*; Rodrigues-Neves AC; Sousa F.J.; Gaspar R.; Almeida I.; Baptista F.I.; Ambrósio A.F.; Gomes C.A.. "Neonatal testosterone voids sexually differentiated microglia morphology and behavior". Front in Endocrinology (2023):
  2. A. Catarina Rodrigues-Neves; António. F. Ambrósio; Catarina A. Gomes. "Microglia sequelae: brain signature of innate immunity in schizophrenia". Translational Psychiatry (2022): https://doi.org/10.1038/s41398-022-02197-1.
    10.1038/s41398-022-02197-1
  3. Ferreira, Ana Sofia; Galvão, Sofia; Gaspar, Rita; Rodrigues-Neves, Ana C.; Ambrósio, António F.; Matafome, Paulo; Gomes, Catarina A.; Baptista, Filipa I.. "Sex-specific changes in peripheral metabolism in a model of chronic anxiety induced by prenatal stress". European Journal of Clinical Investigation 51 12 (2021): http://dx.doi.org/10.1111/eci.13639.
    10.1111/eci.13639
  4. Rodrigues-Neves AC; Carecho R; Correia SC; Carvalho C.; Campos EJ; Baptista FI; Moreira PI; Ambrósio AF. "Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease.". Molecular neurobiology (2021): https://doi.org/10.1007/s12035-021-02316-x.
    10.1007/s12035-021-02316-x
  5. Santiago, Ana Raquel; Madeira, Maria H.; Boia, Raquel; Aires, Inês Dinis; Rodrigues-Neves, A.C.; Santos, Paulo Fernando; Ambrósio, António Francisco. "Keep an eye on adenosine: Its role in retinal inflammation". Pharmacology & Therapeutics (2020): 107513. http://dx.doi.org/10.1016/j.pharmthera.2020.107513.
    Aceite para publicação • 10.1016/j.pharmthera.2020.107513
  6. Salobrar-García, Elena; Rodrigues-Neves, Ana C.; Ramírez, Ana I.; Hoz, Rosa; Fernández-Albarral, José A.; López-Cuenca, Inés; Ramírez, José M.; Ambrósio, Antonio F.; Salazar, Juan J.. "Microglial analysis in whole-mount retina of Alzheimer's disease 3xTg-AD mouse model". International Journal of Molecular Sciences 21 3 (2020): http://dx.doi.org/10.1111/j.1755-3768.2019.5270.
    10.3390/ijms21030816
  7. Aires ID; Madeira MH; Boia R; Rodrigues-Neves AC; Ambrósio AF. "Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice.". Scientific Reports 9 1 (2019):
    Publicado • 10.1038/s41598-019-53627-y
  8. Chiquita, S.; Rodrigues-Neves, A.C.; Baptista, F.I.; Carecho, R.; Moreira, P.I.; Castelo-Branco, M.; Ambrósio, A.F.. "The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer’s Disease: Critical Aspects to Unravel". Molecular Neurobiology 56 8 (2019): 5416-5435. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059597739&partnerID=MN8TOARS.
    10.1007/s12035-018-1461-6
  9. Chiquita, S.; Ribeiro, M.; Castelhano, J.; Oliveira, F.; Sereno, J.; Batista, M.; Abrunhosa, A.; et al. "A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss". Human Molecular Genetics 28 13 (2019): 2174-2188. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068494943&partnerID=MN8TOARS.
    10.1093/hmg/ddz045
  10. Aires, I.D.; Boia, R.; Rodrigues-Neves, A.C.; Madeira, M.H.; Marques, C.; Ambrósio, A.F.; Santiago, A.R.. "Blockade of microglial adenosine A 2A receptor suppresses elevated pressure-induced inflammation, oxidative stress, and cell death in retinal cells". GLIA 67 5 (2019): 896-914. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060525559&partnerID=MN8TOARS.
    10.1002/glia.23579
  11. Rodrigues-Neves, A.C.; Aires, I.D.; Vindeirinho, J.; Boia, R.; Madeira, M.H.; Gonçalves, F.Q.; Cunha, R.A.; et al. "Elevated pressure changes the purinergic system of microglial cells". Frontiers in Pharmacology 9 JAN (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041097386&partnerID=MN8TOARS.
    10.3389/fphar.2018.00016
  12. Boia, R.; Elvas, F.; Madeira, M.H.; Aires, I.D.; Rodrigues-Neves, A.C.; Tralhão, P.; Szabó, E.C.; et al. "Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage". Cell Death and Disease 8 10 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041823993&partnerID=MN8TOARS.
    10.1038/cddis.2017.451
Poster em conferência
  1. Monteiro J.; Grilo L.F.; Rodrigues-Neves AC; Cortes L.; Caldeira M.; Ambrósio A.F.; Pereira S.P.; Gomes C.A.. "Mitochondria, potential drivers of microglia responses to stress". Trabalho apresentado em Champalimaud Research Neuro Symposium, Lisboa, Portugal., 2023.
  2. Rodrigues-Neves AC; Coimbra B.; Gaspar R.; Domingues V.; Soares-Cunha C.; Patrício P.; Pereira M.I.; et al. "The atrophy of microglia cellular processes in adolescent rodents is associated with the hyperfunction of specific neuronal pathways". Trabalho apresentado em Champalimaud Research Neuro Symposium, Lisboa, Portugal., 2023.
  3. Rodrigues-Neves AC; Coimbra B.; Gaspar R.; Domingues V.; Soares-Cunha C.; Patrício P.; Pinto L.; et al. "Analysis of dopaminergic dysfunctions, social deficits and temporal pattern of microglia differentiation in a model of schizophrenia". Trabalho apresentado em FENS regional meeting, Albufeira, Portugal, 2023.
  4. Rodrigues-Neves AC; Coimbra B.; Gaspar R.; Domingues V.; Soares-Cunha C.; Patrício P.; Pinto L.; et al. "Analysis of dopaminergic dysfunctions, social deficits and temporal pattern of microglia differentiation in a model of schizophrenia". Trabalho apresentado em VII Symposium of the Portuguese Glial Network, Albufeira, Portugal., 2023.
  5. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Hipo- and hyperfunctional dopaminergic pathways in schizophrenia diverge in microglia phenotypes". Trabalho apresentado em XVII Meeting of Portuguese Society for Neuroscience (SPN), 2021.
  6. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Distinct microglia phenotypes in hipo- and hyperfunctional dopaminergic pathways from an animal model of schizophrenia". Trabalho apresentado em V Symposium of the Portuguese Glial Network, 2021.
  7. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Microglia, a key element in schizophrenia pathophysiology: insights from an animal model". Trabalho apresentado em European Molecular Biology Laboratory (EMBL meeting) – Microglia workshop, 2021.
  8. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Contrasting morphometric signatures of microglia from hyper- and hypofunctional dopaminergic pathways in an animal model of Schizophrenia". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease, 2021.
  9. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Microglia plasticity: sex specificities in a model of schizophrenia". Trabalho apresentado em PsychoNeuroImmunology Research Society meeting 2021, 2021.
  10. Rodrigues-Neves AC; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B; et al. "Divergent microglia morphological alterations in brain regions associated with hyper- and hipofunctional neuronal pathways in a rodent model of schizophrenia". Trabalho apresentado em 14th Göttingen Meeting 2021, 2021.
  11. Rodrigues-Neves, Ana C.; Gaspar, R; Patrício, P; Lima, S; Rosa, T; Macedo, J; Araújo, B.; et al. "Microglia morphologic characterization in brain regions associated with hyper- and hipofunctional neuronal pathways in a rodent model of schizophrenia". Trabalho apresentado em 3rd Symposium on Physiology and pathology of neuroglia, 2020.
    10.1109/iembs.2009.5333771
  12. Ana I. Ramirez; Elena Salobrar-Garcia; Rodrigues-Neves AC; Juan J. Salazar; Rosa de Hoz; Jose A. Fernandez-Albarral; Ines Lopez-Cuenca; et al. "Microglial analysis in whole-mount retina of Alzheimer’s Disease 3xTg-AD mouse model". Trabalho apresentado em XXI EVER congress, Nice, France, 2019.
  13. Rodrigues-Neves AC; Rafael Carecho; Filipa I. Baptista; Paula I. Moreira; António F. Ambrósio. "Do the retina and brain share similar glial patterns in an animal model of Alzheimer’s disease?". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease, Porto, Portugal., 2019.
  14. Rodrigues-Neves AC; Rafael Carecho; Filipa I. Baptista; Paula I. Moreira; António F. Ambrósio. "Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease?". Trabalho apresentado em SPN 2019, Lisboa, Portugal, 2019.
  15. Sofia Galvão; Sofia Ferreira; Inês Ventura; Rita Gaspar; Rodrigues-Neves AC; Carlos A. Fontes-Ribeiro; António F. Ambrósio; Filipa I. Baptista; Catarina A. Gomes. "Prenatal exposure to stress mediators disturbs early neurodevelopment in a sex-specific manner". Trabalho apresentado em Sex diferences, dimorphisms, divergences: impact on brain and behaviour in health and disease, Sicily, Italy, 2019.
  16. Rodrigues-Neves AC; Rafael Carecho; Elisa Campos; Paula I. Moreira; Filipa I. Baptista; António F. Ambrósio. "Is the retina a reliable mirror of Alzheimer’s disease brain? screening of molecular and cellular parameters.". Trabalho apresentado em in ISER meeting, Belfast, Northern Ireland, UK., 2018.
  17. António F. Ambrósio; Rodrigues-Neves AC; Samuel Chiquita; Rafael Carecho; Filipa I. Baptista; Elisa Campos; Paula I. Moreira. "Structural, functional and molecular alterations in the retina of a mouse model of Alzheimer’s disease". Trabalho apresentado em ARVO meeting, Honolulu, Hawaii., 2018.
  18. Rodrigues-Neves AC; Inês Almeida; Carla Henriques; António F. Ambrósio; Carlos A. Fontes-Ribeiro. "Regulation of microglia physiology by glucocorticoids: comparative analysis between dexamethasone and betamethasone". Trabalho apresentado em EMBL meeting – Microglia workshop, Heidelberg, Germany., 2018.
  19. Rodrigues-Neves AC; Chiquita, S; Carecho, R; Baptista, FI; Moreira, PI; Ambrósio, AF. "Can the retina mirror the alterations observed in Alzheimer’s disease brain at early stages?". Trabalho apresentado em Portuguese Glial Network, 2018.
  20. A. Catarina Rodrigues Neves; Samuel Chiquita; Rafael Carecho; Elisa Campos; Paula I. Moreira; Filipa I. Baptista; António F. Ambrósio. "Alzheimer’s disease: can the retina be a window to the brain?". Trabalho apresentado em XX EVER congress, Nice, France., 2017.
  21. Rodrigues-Neves AC; Samuel Chiquita; Rafael Carecho; Filipa I. Baptista; Paula I. Moreira; António F. Ambrósio. "The retina as a mirror of the alterations observed in Alzheimer’s disease brain? Evaluation of structural, cellular and molecular changes.". Trabalho apresentado em XV SPN, Braga, Portugal., 2017.
  22. Samuel Chiquita; A. Catarina Rodrigues Neves; Rafael Carecho; Filipa I. Baptista; Elisa Campos; Paula I. Moreira; António F. Ambrósio. "Can the retina be used as a reliable mirror to evaluate changes occurring in the Alzheimer’s brain?". Trabalho apresentado em ARVO meeting, Baltimore, USA., 2017.
  23. Carecho, R; Rodrigues-Neves AC; Baptista, FI; Moreira, PI; Ambrósio, AF. "Are the main features of Alzheimer’s brain mirrored by the retina?". 2017.
  24. Rodrigues-Neves AC; Maria H. Madeira; Inês Aires; Raquel Boia; Joana Vindeirinho; A. Ortin-Martinez; M. Vidal-Sanz; et al. "Impact of elevated pressure in the adenosinergic system of microglia and retina.". Trabalho apresentado em XXII ISER meeting, Tokyo, Japan., 2016.
  25. Inês Aires; Raquel Boia; Rodrigues-Neves AC; Maria H. Madeira; António F. Ambrósio; Ana Raquel Santiago. "A2A receptor blockade prevents microglia reactivity triggered by elevated hydrostatic pressure.". Trabalho apresentado em XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain., 2015.
  26. Rodrigues-Neves AC; Inês Aires; Joana Vindeirinho; Raquel Boia; António F. Ambrósio; Ana Raquel Santiago. "Impact of elevated pressure in the adenosinergic system and in the release of proinflammatory cytokines in microglia.". Trabalho apresentado em XIV Meeting of the Portuguese Society for Neuroscience (SPN), Póvoa do Varzim, Portugal., 2015.
  27. Rodrigues-Neves AC; Inês Aires; Joana Vindeirinho; Raquel Boia; António F. Ambrósio; Ana Raquel Santiago. "Extracellular adenosine levels and A2A receptor increase in BV-2 microglia following elevated pressure exposure.". Trabalho apresentado em In4med, Coimbra, Portugal., 2015.
  28. Rodrigues-Neves AC; Inês Aires; Joana Vindeirinho; Raquel Boia; António F. Ambrósio; Ana Raquel Santiago. "Elevated hydrostatic pressure increases extracellular adenosine and A2A receptor protein in BV-2 microglia.". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society (SPB), Coimbra, Portugal., 2014.
  29. Rodrigues-Neves AC; Inês Aires; Joana Vindeirinho; Raquel Boia; António F. Ambrósio; Ana Raquel Santiago. "Elevated hydrostatic pressure increases extracellular adenosine and A2A receptor protein in BV-2 microglia.". Trabalho apresentado em V PF2MUS Symposium “Zoom in microglia”, Coimbra, Portugal., 2014.
  30. Rodrigues-Neves AC; Inês Aires; Joana Vindeirinho; Raquel Boia; António F. Ambrósio; Ana Raquel Santiago. "High pressure increases extracellular adenosine and A2A receptor protein levels in microglia.". Trabalho apresentado em VI annual meeting of IBILI, Coimbra, Portugal., 2014.
Resumo em conferência
  1. Rodrigues-Neves AC. "Contrasting morphometric signatures of microglia from hyper and hypofunctional dopaminergic pathways in an animal model of Schizophrenia". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease, 2021.
    Publicado
  2. Rodrigues-Neves AC; Gaspar R.; Patrício P.; Lima S.; Rosa T.; Macedo J.; Araújo B.; et al. "Hipo and hyperfunctional dopaminergic pathways in schizophrenia diverge in microglia phenotypes". Trabalho apresentado em XVII Meeting of Portuguese Society for Neuroscience (SPN), Coimbra, 2021.
    Publicado
  3. Rodrigues-Neves AC; Carecho, R; Baptista, FI; Moreira, PI; Ambrósio, AF. "Do the retina and brain share similar glial patterns in an animal model of Alzheimer’s disease?". Trabalho apresentado em XIV European Meeting on Glial Cells in Health and Disease, 2019.
    Publicado
  4. Rodrigues-Neves AC; Carecho, R; Baptista, FI; Moreira, PI; Ambrósio, AF. "Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease?". Trabalho apresentado em SPN 2017, Lisboa, 2019.
    Publicado
  5. Ramirez, AI; Salobrar-García, E; Rodrigues-Neves AC; Salazar, JJ; de Hoz, R; Fernandez-Albarral, JA; Cuenca-Lopez, I; et al. "Microglial analysis in whole-mount retina of Alzheimer’s Disease 3xTg-AD mouse model.". Trabalho apresentado em EVER 2019, Nice, 2019.
    Publicado
  6. Ambrósio, AF; Rodrigues-Neves AC; Chiquita, S; Carecho, R; Baptista, F; Campos, E; Moreira, PI. "Structural, functional and molecular alterations in the retina of a mouse model of Alzheimer’s disease". Trabalho apresentado em ARVO 2018, Honolulu, 2018.
    Publicado
  7. Chiquita, S; Rodrigues-Neves AC; Carecho, R; Baptista, FI; Campos, E; Moreira, PI; Ambrósio, AF. "Can the retina be used as a reliable mirror to evaluate changes occurring in the Alzheimer’s brain?". Trabalho apresentado em ARVO 2017, Baltimore, 2017.
    Publicado
  8. Rodrigues-Neves AC; Chiquita, S; Carecho, R; Campos, E; Moreira, PI; Baptista, FI; Ambrósio, AF. "Alzheimer’s disease: can the retina be a window to the brain?". Trabalho apresentado em EVER 2017, Nice, 2017.
    Publicado
  9. Aires, ID; Rodrigues-Neves AC; Boia, R; Madeira, MH; Ambrósio, AF; Santiago, AR. "A2A receptor blockade prevents microglia reactivity triggered by elevated hydrostatic pressure.". Bilbao, 2015.
    Publicado
Tese / Dissertação
  1. "Putative role of microglia dimorphism in schizophrenia gender differences". Doutoramento, Universidade de Coimbra Faculdade de Farmácia, 2024.
  2. Rodrigues-Neves AC. "The impact of elevated hydrostatic pressure in microglia: changes in the adenosinergic system and inflammatory responses". Mestrado, CNC.IBILI, 2015.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/05/26 Esquizofrenia e imunidade: alteração fenotípica da microglia 1st PhDoing, Coimbra, Portugal
2023/02 Microglia in brain regions targeted by hypo- and hyperfunctional dopaminergic neurons in schizophrenia present divergent morphologic phenotypes at adolescence 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
(Coimbra, Portugal)
2022/02/11 Characterization of disease-associated microglia upon the prenatal exposure to the toxin methylazoxymethanol acetate LII Annual meeting of Portuguese Society for Pharmacology (SPF), XL Clinic Pharmacology meeting, XXI Toxicology meeting
2021 Physiological sex diferences in microglia and behaviour: organizationl effects of testosterone. in XLI Annual meeting of Portuguese Society for Pharmacology (SPF), XXXIX Clinic Pharmacology meeting, XX Toxicology meeting
2021 Microglia morphology in hypo- and hyperfunctional pathways: insights from a rodent model of schizophrenia XLI Annual meeting of Portuguese Society for Pharmacology (SPF), XXXIX Clinic Pharmacology meeting, XX Toxicology meeting
2020/02/07 Early developmental and social deficits in an animal model of schizophrenia: new clues anticipating diagnosis? SPF 2020
Sociedade Portuguesa da Farmacologia (Coimbra, Portugal)
2020/02/07 Prenatal exposure to dexamethasone improves offspring development in a sex-independent manner SPF 2020
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2019/04/05 Neurodevelopmental assessment may anticipate chronic anxiety states at adulthood in individuals prenatally exposed to glucocorticoids ESTeSC Annual Meeting 2019
ESTeSC (Coimbra, Portugal)
2019/04/05 Prenatal exposure to betamethasone delays vestibular system development comparing with dexamethasone ESTeSC Annual Meeting 2019
ESTeSC (Coimbra, Portugal)
2019/04 Antenatal glucocorticoid impact in peripheral metabolism: gender-specific alterations in glycemia levels ESTeSC Annual Meeting 2019
ESTeSC (C, Portugal)
2019/02/08 Neurodevelopmental assessment in rats prenatally exposed to glucocorticoids may anticipate chronic anxiety states later in life SPF 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2019/02/08 Glucocorticoid Fetal Programming: A comparative study between dexamethasone and betamethasone SPF 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2019/02/06 Gender-specificities of antenatal glucocorticoid exposure: focus on the peripheral metabolismo and glucose homeostasis SPF 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2018/09/11 Is the retina a reliable window to look into the brain in alzheimer's disease? Lessons. from an animal model XXIII Biennial Meeting of the International Society for Eye Research (ISER)
International Society for Eye Research (ISER) (Belfast, Irlanda)
2018 In vitro effects of dexamethasone and betamethasone on microglia: structure-activity correlation study III Encontro Científico do Núcleo de Estudantes de Química
2018 Effects of dexamethasone and betamethasone on brain microglia: structure-activity correlation study XLVIII Reunião Anual da Sociedade Portuguesa de Farmacologia. XXXVI Reunião de Farmacologia Clínica. XVII Reunião de Toxicologia
2017/09/28 Alzheimer’s disease: can the retina be a window to the brain? XX EVER congress
European Association for Vision and Eye Research (EVER) (Nice, França)
2017/02/02 Changes of the adenosinergic system in microglia and retina triggred by elevated pressure SPF 2017
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2016/09/27 Impact of elevated pressure in the adenosinergic system of microglia and retina XXII Biennial Meeting of the International Society for Eye Research
International Society for Eye Research (ISER) (Tokyo, Japão)
2016 Avaliação de alterações celulares e moleculares na retina e cérebro de um modelo animal de doença de Alzheimer (3xTg-AD) Santa Casa Neurociências Conferências 2016
Santa Casa Misericórdia de Lisboa
2015/12/03 Impact of elevated hydrostatic pressure in the adenosinergic system of microglial cells. VII annual meeting of IBILI
iCBR (ex-IBILI) (Coimbra, Portugal)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2023 - Atual Brain Awareness Week consists in a global campaign to foster public enthusiasm and support for brain science. It envolves diverse groups with different interests from academia, government, and professional and advocacy organizations. The goal is sensitize the public for the importance of brain research, focusing themes such treatments, preventions, and possible cures for brain diseases and disorders, and to ensure a better quality of life at all ages.
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2022 - Atual Science and Technology Week has the objective to improve the scientific literacy of school communities in Portugal, to make the school community aware of the importance of science and technology in improving the quality of life and sustainable development, and to promote various activities that stimulate scientific curiosity.
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2021 - Atual Participation in the 2nd edition of the University of Coimbra Three-Minute Thesis Competition
2021 - 2021 European Researchers¿ Nights are public events dedicated to bringing researchers closer to the geral public. The goal is show the diversity of research, highlight the impact of research on our daily lives and motivate young people to embark on research careers. The events promote how researchers contribute to our society by displaying their work in an interactive event.
Coimbra Institute for Clinical and Biomedical Research (iCBR), Portugal
2019/09/27 - 2019/09/27 European Researchers’ Nights are public events dedicated to bringing researchers closer to the geral public. The goal is show the diversity of research, highlight the impact of research on our daily lives and motivate young people to embark on research careers. The events promote how researchers contribute to our society by displaying their work in an interactive event.
Outro
 European Researchers' Night
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2019/03/16 - 2019/03/30 Brain Awareness Week consists in a global campaign to foster public enthusiasm and support for brain science. It envolves diverse groups with different interests from academia, government, and professional and advocacy organizations. The goal is sensitize the public for the importance of brain research, focusing themes such treatments, preventions, and possible cures for brain diseases and disorders, and to ensure a better quality of life at all ages.
Outro
 Brain Awareness Week 2019
CNC.IBILI, Portugal
2018/09/28 - 2018/09/28 European Researchers’ Nights are public events dedicated to bringing researchers closer to the geral public. The goal is show the diversity of research, highlight the impact of research on our daily lives and motivate young people to embark on research careers. The events promote how researchers contribute to our society by displaying their work in an interactive event.
Outro
 European Researchers' Night
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2018/03/17 - 2018/03/31 Brain Awareness Week consists in a global campaign to foster public enthusiasm and support for brain science. It envolves diverse groups with different interests from academia, government, and professional and advocacy organizations. The goal is sensitize the public for the importance of brain research, focusing themes such treatments, preventions, and possible cures for brain diseases and disorders, and to ensure a better quality of life at all ages.
Outro
 Brain Awareness Week 2018
CNC.IBILI, Portugal
2017/03/11 - 2017/03/25 Brain Awareness Week consists in a global campaign to foster public enthusiasm and support for brain science. It envolves diverse groups with different interests from academia, government, and professional and advocacy organizations. The goal is sensitize the public for the importance of brain research, focusing themes such treatments, preventions, and possible cures for brain diseases and disorders, and to ensure a better quality of life at all ages.
Outro
 Brain Awareness Week 2017
CNC.IBILI, Portugal
2017/02/01 - 2017/02/01 Mini-symposium focused in several advanced models for neuroscience research (with international speakers).
Seminário
 Mini-symposium "Advanced models in neuroscience research"
Faculty of Pharmacy, University of Coimbra, Portugal
2016/09/30 - 2016/09/30 European Researchers’ Nights are public events dedicated to bringing researchers closer to the geral public. The goal is show the diversity of research, highlight the impact of research on our daily lives and motivate young people to embark on research careers. The events promote how researchers contribute to our society by displaying their work in an interactive event.
Outro
 European Investigator's Night 2016
Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2016/03/12 - 2016/03/26 Brain Awareness Week consists in a global campaign to foster public enthusiasm and support for brain science. It envolves diverse groups with different interests from academia, government, and professional and advocacy organizations. The goal is sensitize the public for the importance of brain research, focusing themes such treatments, preventions, and possible cures for brain diseases and disorders, and to ensure a better quality of life at all ages.
Outro
 Brain Awareness week 2016
CNC.IBILI, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022 - Atual Animal models of schizophrenia | Discipline: Non-clinical trials | Master in Medicinal Chemistry In vivo assessment of neurodevelopmental milestones in postnatal period & in vivo behavior test to assess antipsychotic effects | Discipline: Non-clinical trials | Master in Medicinal Chemistry Calculation of the number of animals needed for in vivo evaluation of psychoactive drugs effect | Discipline: Non-clinical trials | Master in Medicinal Chemistry
2021 - Atual Animal models of schizophrenia | Discipline: Non-clinical trials | Master in Medicinal Chemistry In vivo assessment of neurodevelopmental milestones in postnatal period & in vivo behavior test to assess antipsychotic effects | Discipline: Non-clinical trials | Master in Medicinal Chemistry Calculation of the number of animals needed for in vivo evaluation of psychoactive drugs effect | Discipline: Non-clinical trials | Master in Medicinal Chemistry
2020 - Atual Calculation of the number of animals needed for in vivo evaluation of anxiolytic/ antidepressive drugs effect | Discipline: Non-clinical trials | Master in Medicinal Chemistry Behavioral tests to assess neurodevelopmental milestones in rodents| Discipline: Non-clinical trials | Master in Medicinal Chemistry
2019 - Atual Tutor of the workshop “Animal experimentation” at VIII In4med, Coimbra, Portugal Instituto de Investigação Clínica e Biomédica de Coimbra (iCBR), Portugal
2017 - Atual “Aging: Retinal diseases associated to inflammatory processes: the role of microglia” | Biology and Aging Physiology | Master integrated in Psychology
2019/01/07 - 2019/01/18 Modular Training in Laboratory Animal Science: Function A, Function B and Special Skills. CNC.IBILI, Portugal
2016/10/24 - 2016/11/03 Advanced course focused on functional neuroanatomy (Professor Wilhelmus Smeets) Center for Neuroscience and Cell Biology (CNC), Portugal
2016/06/27 - 2016/07/01 CECAD Cologne short course on “Entrepreneurial Introductory Translational Research (EITR)” Cluster of Excellence for Aging Research (CECAD), Alemanha

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2017/01 - Atual Sociedade Portuguesa de Farmacologia
Membro
 Sociedade Portuguesa de Farmacologia, Portugal
2015/05 - Atual Sociedade Portuguesa de Neurociências
Membro
 Sociedade Portuguesa de Neurociências, Portugal
Distinções

Prémio

2022 Travel Grant for FENS Forum 2022
2021 Best image - V Symposium of the Portuguese Glial Network

Outra distinção

2023 Scholarship for FENS regional meeting 2023
2021 Stipend for Göttingen Meeting of the German Neuroscience Society (NWG) (virtual)
German Neuroscience Society, Alemanha
2021 Stipend for XIV European Meeting on Glial Cells in Health and Disease (GLIA)
2021 Stipend for PsychoNeuroImmunology Research Society (PNIRS) meeting 2021
2021 Stipend for EMBO Microglia workshop 2021
2021 Scholarship for XVII Portuguese Society for Neuroscience (SPN)
2019 Scholarship for Portuguese Society for Neuroscience (SPN)
Sociedade Portuguesa de Farmacologia, Portugal