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Identificação

Identificação pessoal

Nome completo
Tânia Gilot Mendes de Carvalho

Nomes de citação

  • Carvalho, Tânia

Identificadores de autor

Ciência ID
4C10-5743-02F8
ORCID iD
0000-0002-5283-5013
Formação
Grau Classificação
2022/02/02
Concluído
Medicina Veterinária (Título de Agregado)
Especialização em Patologia Animal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2008
Concluído
Ciências Veterinárias (Doutoramento)
Especialização em PATOLOGIA ANIMAL
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"Morphological and Phenotypical Characterization of Urinary Bladder Lesions in Bovine Enzootic Hematuria" (TESE/DISSERTAÇÃO)
1995/09/15 - 2001/02/01
Concluído
Medicina Veterinária (Mestrado integrado)
Especialização em Patologia Animal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2020/05/01 - Atual Investigador Contratado (Investigação) Fundação Champalimaud, Portugal
2013/02/01 - 2020/04/30 Investigador (Investigação) Instituto de Medicina Molecular, Portugal
2011 - 2013 Investigador Contratado (Investigação) Instituto Gulbenkian de Ciência, Portugal
Projetos

Projeto

Designação Financiadores
2023/01/01 - 2025/12/31 Descobrindo os mecanismos de resistência à formação do cancro no cérebro em desenvolvimento
2022.09083.PTDC
Fundação Champalimaud, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/10/01 - 2021/11/30 Doses de radiação subterapêuticas modulam o nicho pré-metastático e induzem metástases. Quais os mecanismos e como prevenir
PTDC/MED-OUT/31118/2017
Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/08/09 - 2021/08/08 Posicionamento do núcleo das células musculares esqueléticas
PTDC/BIA-CEL/31075/2017
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/06/01 - 2021/05/31 Importância dos Reservatórios de Parasitas Extravasculares em Gado e Modelos Laboratoriais de Ratinhos
PTDC/CVT-CVT/29161/2017
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Fundação Calouste Gulbenkian, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016/07/01 - 2019/12/31 Consequências metabólicas de uma infeção pelo Tripanosoma Africano
PTDC/BIM-MET/4471/2014
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2013/05/01 - 2015/10/31 Metaboloma do Liquido Cefalorraquidiano: instrutivo para a formação de metastases no sistema nervoso central
PTDC/BIM-ONC/1242/2012
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/01/01 - 2015/06/30 O papel do ferro no ciclo de vida e na doença causada por Plasmodium
EXPL/BIM-MET/0753/2013
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/01/01 - 2015/06/30 Análise quantitativa da evolução clonal e caracterização de variantes de escape na recidiva da Leucemia Mielóide Aguda
EXPL/BIM-ONC/1656/2013
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal

Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/03/01 - 2012/05/31 MECHANISMS THAT MODULATE ACUTE LEUKEMIA LOCALIZATION WITHIN BONE MARROW NICHES
SFRH/BPD/41378/2007
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2003/03/01 - 2007/07/31 CARACTERIZAÇÃO MORFOLÓGICA E FENOTÍPICA DAS LESÕES VESICAIS NO ÂMBITO DA HEMATÚRIA ENZOÓTICA BOVINA
SFRH/BD/10355/2002
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Carvalho, Tânia; Andrada Ianus. Autor correspondente: Andrada Ianus. "Soma and Neurite Density Imaging (SANDI) characterizes microscopic differences between two glioma mouse model subtypes". Trabalho apresentado em Annual Meeting of the ISMRM, 2023.
Artigo em revista
  1. Šestan M; Raposo B; Rendas M; Brea D; Pirzgalska R; Rasteiro A; Aliseychik M; et al. "Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis.". Science (New York, N.Y.) (2025): http://europepmc.org/abstract/med/39818880.
    10.1126/science.adi3624
  2. Perera C; Cruz R; Shemesh N; Carvalho T; Thomas DL; Wells J; Ianu¿ A. "Non-invasive MRI of blood-cerebrospinal fluid-barrier function in a mouse model of Alzheimer's disease: a potential biomarker of early pathology.". Fluids and barriers of the CNS (2024): http://europepmc.org/abstract/med/39633378.
    10.1186/s12987-024-00597-7
  3. Lopes-Bastos B; Nabais J; Ferreira T; Allavena G; El Maï M; Bird M; Targen S; et al. "The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma.". Cell reports (2024): http://europepmc.org/abstract/med/39643971.
    10.1016/j.celrep.2024.115035
  4. Bilreiro C; Fernandes FF; Simões RV; Henriques R; Chavarrías C; Ianus A; Castillo-Martin M; et al. "Pancreatic Intraepithelial Neoplasia Revealed by Diffusion-Tensor MRI.". Investigative radiology (2024): http://europepmc.org/abstract/med/39668406.
    10.1097/rli.0000000000001142
  5. Constâncio, V.; Carvalho, T.; Leite-Silva, P.; Leung, H.; Costa-Silva, B.; Jerónimo, C.. "A novel translational immunocompetent model for investigating prostate cancer bone metastasis". European Urology Open Science 56 (2023): S5. http://dx.doi.org/10.1016/s2666-1683(23)01093-5.
    10.1016/s2666-1683(23)01093-5
  6. Wong, Kim; Abascal, Federico; Ludwig, Latasha; Aupperle-Lellbach, Heike; Grassinger, Julia; Wright, Colin W.; Allison, Simon J.; et al. "Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer". Genome Biology 24 1 (2023): http://dx.doi.org/10.1186/s13059-023-03026-4.
    10.1186/s13059-023-03026-4
  7. Maria Rebelo; Cong Tang; Ana R Coelho; Carlos Labão-Almeida; Matthias M Schneider; Laurie Tatalick; Pedro Ruivo; et al. "De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection". The Journal of Infectious Diseases (2023): http://dx.doi.org/10.1093/infdis/jiad135.
    10.1093/infdis/jiad135
  8. Marinho, Pedro F; Vieira, Soraia L; Carvalho, Tânia G; Peleteiro, Maria C; Hanscheid, Thomas. "A novel and simple heat-based method eliminates the highly detrimental effect of xylene deparaffinization on acid-fast stains". American Journal of Clinical Pathology 160 1 (2023): 81-88. http://dx.doi.org/10.1093/ajcp/aqad016.
    10.1093/ajcp/aqad016
  9. Ângelo Ferreira Chora; Sofia Marques; Joana Lisboa Gonçalves; Priscila Lima; Daniel Gomes da Costa; Daniel Fernandez-Ruiz; Maria Inês Marreiros; et al. "Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via ¿d T cells and IL-17-promoted stress erythropoiesis". Immunity 56 3 (2023): 592-605.e8. http://dx.doi.org/10.1016/j.immuni.2023.01.031.
    10.1016/j.immuni.2023.01.031
  10. Papotto, Pedro H.; Yilmaz, Bahtiyar; Pimenta, Gonçalo; Mensurado, Sofia; Cunha, Carolina; Fiala, Gina J.; Gomes da Costa, Daniel; et al. "Maternal ¿d T cells shape offspring pulmonary type 2 immunity in a microbiota-dependent manner". Cell Reports 42 2 (2023): 112074. http://dx.doi.org/10.1016/j.celrep.2023.112074.
    10.1016/j.celrep.2023.112074
  11. Tang, Cong; Coelho, Ana R.; Rebelo, Maria; Kiely-Collins, Hannah; Carvalho, Tânia; Bernardes, Gonçalo J. L.. "A Selective SARS-CoV-2 Host-Directed Antiviral Targeting Stress Response to Reactive Oxygen Species". ACS Central Science 9 1 (2023): 109-121. http://dx.doi.org/10.1021/acscentsci.2c01243.
    10.1021/acscentsci.2c01243
  12. Eunice Paisana; Rita Cascão; Carlos Custódia; Nan Qin; Daniel Picard; David Pauck; Tânia Carvalho; et al. "UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease". Neuro-Oncology Advances 5 1 (2023): http://dx.doi.org/10.1093/noajnl/vdad048.
    10.1093/noajnl/vdad048
  13. Faria CC; Cascão R; Custódia C; Paisana E; Carvalho T; Pereira P; Roque R; et al. "Patient-derived models of brain metastases recapitulate human disseminated disease.". Cell reports. Medicine (2022): http://europepmc.org/abstract/med/35584628.
    10.1016/j.xcrm.2022.100623
  14. Dos Santos Rocha A; Petak F; Carvalho T; Habre W; Balogh AL. "Physiologically variable ventilation prevents lung function deterioration in a model of pulmonary fibrosis.". Journal of applied physiology (Bethesda, Md. : 1985) (2022): http://europepmc.org/abstract/med/35201935.
    10.1152/japplphysiol.00670.2021
  15. Simões RV; Henriques RN; Cardoso BM; Fernandes FF; Carvalho T; Shemesh N. "Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma.". NeuroImage. Clinical (2022): http://europepmc.org/abstract/med/35026626.
    10.1016/j.nicl.2021.102932
  16. Henrique Machado; Stefan Magez; Tiago Bizarra-Rebelo; Mariana Costa-Sequeira; Sandra Trindade; Tânia Carvalho; Filipa Rijo-Ferreira; et al. "Trypanosoma brucei triggers a broad immune response in the adipose tissue". PLOS Pathogens 17 9 (2021): e1009933-e1009933. https://doi.org/10.1371/journal.ppat.1009933.
    10.1371/journal.ppat.1009933
  17. Mariana Tavares Barroso; Bruna Costa; Cátia Rebelo de Almeida; Mireia Castillo Martin; Nuno Couto; Tânia Carvalho; Rita Fior. "Establishment of Pancreatobiliary Cancer Zebrafish Avatars for Chemotherapy Screening". Cells (2021): https://doi.org/10.3390/cells10082077.
    10.3390/cells10082077
  18. Paisana E; Cascão R; Custódia C; Qin N; Picard D; Pauck D; Carvalho T; et al. "LMD-12. Ubiquitin Conjugating Enzymes promote leptomeningeal dissemination and decrease survival in patients with brain metastatic disease". Neuro-oncology advances (2021): http://europepmc.org/abstract/PMC/PMC8351197.
  19. David K. Meyerholz; Hibret A. Adissu; Tania Carvalho; Hannah M. Atkins; Daniel R. Rissi; Amanda P. Beck; Jerrold M. Ward; Alessandra Piersigilli. "Exclusion of Expert Contributors From Authorship Limits the Quality of Scientific Articles". Veterinary Pathology (2021): 030098582110119-030098582110119. https://doi.org/10.1177/03009858211011943.
    10.1177/03009858211011943
  20. Conde J; Pumroy RA; Baker C; Rodrigues T; Guerreiro A; Sousa BB; Marques MC; et al. "Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.". ACS central science (2021): http://europepmc.org/abstract/med/34079902.
    10.1021/acscentsci.1c00070
  21. Melo, Bernardete F.; Prieto-Lloret, Jesus; Cabral, Marlene D.; Martins, Fatima O.; Martins, Inês B.; Sacramento, Joana F.; Ruivo, Pedro; Carvalho, Tânia; Conde, Silvia. V. "Type 2 diabetes progression differently affects endothelial function and vascular contractility in the aorta and the pulmonary artery". Scientific Reports (2021):
    Aceite para publicação
  22. Fábio A. Abade dos Santos; Andreia Pinto; Thomas Burgoyne; Kevin P. Dalton; Carina L. Carvalho; David W. Ramilo; Carla Carneiro; et al. "Spillover events of rabbit haemorrhagic disease virus 2 (recombinant GI.4P-GI.2) from Lagomorpha to Eurasian badger". Transboundary and Emerging Diseases (2021): https://doi.org/10.1111/tbed.14059.
    10.1111/tbed.14059
  23. João Fonseca-Gomes; Joana A Loureiro; Sara R Tanqueiro; Francisco M Mouro; Pedro Ruivo; Tânia Carvalho; Ana M Sebastião; Maria José Diógenes; Maria Carmo Pereira. "

    In vivo Bio-Distribution and Toxicity Evaluation of Polymeric and Lipid-Based Nanoparticles: A Potential Approach for Chronic Diseases Treatment

    ". International Journal of Nanomedicine (2020): https://doi.org/10.2147/IJN.S267007.
    10.2147/IJN.S267007
  24. Gil Marques, Filipa; Poli, Esmeralda; Malaquias, João; Carvalho, Tânia; Portêlo, Ana; Ramires, Afonso; Aldeia, Fernando; et al. "Erratum to "Low doses of ionizing radiation activate endothelial cells and induce angiogenesis in peritumoral tissues" [Radiotherapy and Oncology 141 (2019) 256-261]". Radiotherapy and Oncology 151 (2020): e1. http://dx.doi.org/10.1016/j.radonc.2020.06.037.
    Publicado • 10.1016/j.radonc.2020.06.037
  25. Cascão R; Vidal B; Carvalho T; Lopes IP; Romão VC; Goncalves J; Moita LF; Fonseca JE. "Celastrol Efficacy by Oral Administration in the Adjuvant-Induced Arthritis Model.". Frontiers in medicine (2020): http://europepmc.org/abstract/med/33015082.
    10.3389/fmed.2020.00455
  26. Gil Marques F; Poli E; Malaquias J; Carvalho T; Portêlo A; Ramires A; Aldeia F; et al. "Low doses of ionizing radiation activate endothelial cells and induce angiogenesis in peritumoral tissues.". Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2020): http://europepmc.org/abstract/med/33004178.
    10.1016/j.radonc.2020.06.038
  27. Wilharm A; Brigas HC; Sandrock I; Ribeiro M; Amado T; Reinhardt A; Demera A; et al. "Microbiota-dependent expansion of testicular IL-17-producing V¿6+ ¿d T cells upon puberty promotes local tissue immune surveillance.". Mucosal immunology (2020): http://europepmc.org/abstract/med/32733025.
    10.1038/s41385-020-0330-6
  28. Mariana De Niz; Tânia Carvalho; Carlos Penha-Gonçalves; Carolina Agop-Nersesian. "Intravital imaging of host-parasite interactions in organs of the thoracic and abdominopelvic cavities". Cellular Microbiology (2020): https://doi.org/10.1111/cmi.13201.
    10.1111/cmi.13201
  29. Lex K; Maia Gil M; Lopes-Bastos B; Figueira M; Marzullo M; Giannetti K; Carvalho T; Ferreira MG. "Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish.". Proceedings of the National Academy of Sciences of the United States of America (2020): http://europepmc.org/abstract/med/32554492.
    10.1073/pnas.1920049117
  30. Vala H; Carvalho T; Pinto C; Pereira MA; Mesquita JR; C Peleteiro M; Ferrer L; Fondevila D. "Immunohistochemical Studies of Cytokeratins and Differentiation Markers in Bovine Ocular Squamous Cell Carcinoma.". Veterinary sciences (2020): http://europepmc.org/abstract/med/32485997.
    10.3390/vetsci7020070
  31. Carvalho, Tânia. "An antisense transcript mediates MALAT1 response in human breast cancer". BMC Cancer (2019): http://dx.doi.org/10.1186/s12885-019-5962-0.
    10.1186/s12885-019-5962-0
  32. Carvalho, Tânia. "Trypanosoma brucei infection protects mice against malaria". PLOS Pathogens (2019): http://dx.doi.org/10.1371/journal.ppat.1008145.
    10.1371/journal.ppat.1008145
  33. Caiado, Francisco; Maia-Silva, Diogo; Jardim, Carolina; Schmolka, Nina; Carvalho, Tânia; Reforço, Cláudia; Faria, Rita; et al. "Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection". Nature Communications 10 1 (2019): http://dx.doi.org/10.1038/s41467-019-12983-z.
    10.1038/s41467-019-12983-z
  34. Carvalho, Tânia; Cristina Godinho-Silva; Rita G. Domingues; Miguel Rendas; Bruno Raposo; Hélder Ribeiro; Joaquim Alves da Silva; et al. "Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeostasis". Nature (2019): http://dx.doi.org/10.1038/s41586-019-1579-3.
    10.1038/s41586-019-1579-3
  35. Carvalho, Tânia. "Modulation of CD4 T cell function via CD6-targeting". EBioMedicine (2019): http://dx.doi.org/10.1016/j.ebiom.2019.08.008.
    10.1016/j.ebiom.2019.08.008
  36. Carvalho, Tânia. "A fully human anti-IL-7Ra antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia". Leukemia (2019): http://dx.doi.org/10.1038/s41375-019-0434-8.
    10.1038/s41375-019-0434-8
  37. Carvalho, Tânia. "Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration". Journal of Visualized Experiments (2019): http://dx.doi.org/10.3791/59798.
    10.3791/59798
  38. Carvalho, Tânia. "Azithromycin does not improve disease severity in acute experimental pancreatitis". PLOS ONE (2019): http://dx.doi.org/10.1371/journal.pone.0216614.
    10.1371/journal.pone.0216614
  39. Carvalho, Tânia. "¿d-T cells promote IFN-¿–dependent Plasmodium pathogenesis upon liver-stage infection". Proceedings of the National Academy of Sciences (2019): http://dx.doi.org/10.1073/pnas.1814440116.
    10.1073/pnas.1814440116
  40. Carvalho, Tânia. "Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells". Cancer Immunology Research (2019): http://dx.doi.org/10.1158/2326-6066.cir-18-0647.
    10.1158/2326-6066.cir-18-0647
  41. Carvalho, Tânia. "Silencing of the lncRNA Zeb2-NAT facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency". Nature Communications (2018): http://dx.doi.org/10.1038/s41467-017-01921-6.
    10.1038/s41467-017-01921-6
  42. Carvalho, Tânia. "Trypanosoma brucei triggers a marked immune response in male reproductive organs". PLOS Neglected Tropical Diseases (2018): http://dx.doi.org/10.1371/journal.pntd.0006690.
    10.1371/journal.pntd.0006690
  43. Carvalho, Tânia. "Development of nanoparticles from natural lipids for topical delivery of thymol: Investigation of its anti-inflammatory properties". Colloids and Surfaces B: Biointerfaces (2018): http://dx.doi.org/10.1016/j.colsurfb.2018.01.053.
    10.1016/j.colsurfb.2018.01.053
  44. Rijo-Ferreira F; Carvalho T; Afonso C; Sanches-Vaz M; Costa RM; Figueiredo LM; Takahashi JS. "Sleeping sickness is a circadian disorder.". Nature communications (2018): http://europepmc.org/abstract/med/29302035.
    10.1038/s41467-017-02484-2
  45. Nóbrega-Pereira S; Caiado F; Carvalho T; Matias I; Graça G; Gonçalves LG; Silva-Santos B; Norell H; Dias S. "VEGFR-2-mediated reprogramming of mitochondrial metabolism regulates the sensitivity of acute myeloid leukemia to chemotherapy.". Cancer research (2017): http://europepmc.org/abstract/med/29229602.
    10.1158/0008-5472.can-17-1166
  46. Afonso MB; Rodrigues PM; Simão AL; Gaspar MM; Carvalho T; Borralho P; Bañales JM; Castro RE; Rodrigues CMP. "miRNA-21 ablation protects against liver injury and necroptosis in cholestasis.". Cell death and differentiation (2017): http://europepmc.org/abstract/med/29229992.
    10.1038/s41418-017-0019-x
  47. Graça, Gonçalo; Desterro, Joana; Sousa, Joana; Fonseca, Carlos; Silveira, Margarida; Serpa, Jacinta; Carvalho, Tânia; da Silva, Maria G.; Gonçalves, Luís G.. "Identification of putative biomarkers for leptomeningeal invasion in B-cell non-Hodgkin lymphoma by NMR metabolomics". Metabolomics 13 11 (2017): http://dx.doi.org/10.1007/s11306-017-1269-9.
    10.1007/s11306-017-1269-9
  48. Lopes-Coelho F; Nunes C; Gouveia-Fernandes S; Rosas R; Silva F; Gameiro P; Carvalho T; et al. "Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells.". Oncotarget (2017): http://europepmc.org/abstract/med/29137304.
    10.18632/oncotarget.20294
  49. Carvalho, Tânia. "Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts.". Proceedings of the National Academy of Sciences of the United States of America (2017): http://europepmc.org/abstract/med/28835536.
    10.1073/pnas.1618389114
  50. Carvalho, Tânia. "Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.". Nature (2017): http://europepmc.org/abstract/med/28869974.
    10.1038/nature23469
  51. Carvalho, Tânia. "Dietary alterations modulate susceptibility to Plasmodium infection.". Nature microbiology (2017): http://europepmc.org/abstract/med/28947801.
    10.1038/s41564-017-0025-2
  52. Carvalho, Tânia. "Low-dose ionizing radiation induces therapeutic neovascularization in a pre-clinical model of hindlimb ischemia.". Cardiovascular research (2017): http://europepmc.org/abstract/med/28444128.
    10.1093/cvr/cvx065
  53. Carvalho, Tânia. "CLEM analysis of the angiogenic process in a zebrafish model of spinal cord injury.". Ultrastructural pathology (2017): http://europepmc.org/abstract/med/28230492.
    10.1080/01913123.2016.1272150
  54. Hänscheid, T.; Carvalho, T.; Grobusch, M.P.. "Hemozoin Detection for Human Malaria Diagnosis Investigated in Rodent Models: How Similar Is Similar?". Trends in Parasitology 32 2 (2016): 94-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959163087&partnerID=MN8TOARS.
    10.1016/j.pt.2015.11.012
  55. Pereira, D.M.; Simões, A.E.S.; Gomes, S.E.; Castro, R.E.; Carvalho, T.; Rodrigues, C.M.P.; Borralho, P.M.. "MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism". Oncotarget 7 23 (2016): 34322-34340. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973664372&partnerID=MN8TOARS.
    10.18632/oncotarget.9107
  56. Correia, N.C.; Fragoso, R.; Carvalho, T.; Enguita, F.J.; Barata, J.T.. "MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84984646240&partnerID=MN8TOARS.
    10.1038/srep31894
  57. Ibiza, S.; García-Cassani, B.; Ribeiro, H.; Carvalho, T.; Almeida, L.; Marques, R.; Misic, A.M.; et al. "Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence". Nature 535 7612 (2016): 440-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978128198&partnerID=MN8TOARS.
    10.1038/nature18644
  58. Carneiro, M.C.; Henriques, C.M.; Nabais, J.; Ferreira, T.; Carvalho, T.; Ferreira, M.G.. "Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish". PLoS Genetics 12 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84958730300&partnerID=MN8TOARS.
    10.1371/journal.pgen.1005798
  59. Trindade, S.; Rijo-Ferreira, F.; Carvalho, T.; Pinto-Neves, D.; Guegan, F.; Aresta-Branco, F.; Bento, F.; et al. "Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice". Cell Host and Microbe 19 6 (2016): 837-848. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969909575&partnerID=MN8TOARS.
    10.1016/j.chom.2016.05.002
  60. Afonso, M.B.; Rodrigues, P.M.; Carvalho, T.; Caridade, M.; Borralho, P.; Cortez-Pinto, H.; Castro, R.E.; Rodrigues, C.M.P.. "Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis". Clinical Science 129 8 (2015): 721-739. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942872734&partnerID=MN8TOARS.
    10.1042/CS20140732
  61. Simões, A.; Pereira, D.M.; Gomes, S.E.; Brito, H.; Carvalho, T.; French, A.; Castro, R.E.; et al. "Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-¿B activation". Cell Death and Disease 6 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84989924728&partnerID=MN8TOARS.
    10.1038/cddis.2015.83
  62. Nunes-Cabaço, H.; Matoso, P.; Foxall, R.B.; Tendeiro, R.; Pires, A.R.; Carvalho, T.; Pinheiro, A.I.; Soares, R.S.; Sousa, A.E.. "Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes". Journal of Virology 89 4 (2015): 2201-2208. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921633227&partnerID=MN8TOARS.
    10.1128/JVI.03047-14
  63. Ng, S.; March, S.; Galstian, A.; Hanson, K.; Carvalho, T.; Mota, M.M.; Bhatia, S.N.. "Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro". Disease models & mechanisms 7 2 (2014): 215-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928332974&partnerID=MN8TOARS.
    10.1242/dmm.013490
  64. Boura, M.; Frita, R.; Góis, A.; Carvalho, T.; Hänscheid, T.. "The hemozoin conundrum: Is malaria pigment immune-activating, inhibiting, or simply a bystander?". Trends in Parasitology 29 10 (2013): 469-476. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884404504&partnerID=MN8TOARS.
    10.1016/j.pt.2013.07.005
  65. Caiado, F.; Carvalho, T.; Rosa, I.; Remédio, L.; Costa, A.; Matos, J.; Heissig, B.; et al. "Bone marrow-derived CD11b+Jagged2+ cells promote epithelial-to-mesenchymal transition and metastasization in colorectal cancer". Cancer Research 73 14 (2013): 4233-4246. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880873734&partnerID=MN8TOARS.
    10.1158/0008-5472.CAN-13-0085
  66. Cota, J. B.; Carvalho, T.; Pinto, C.; Peleteiro, M. C.; Cota, J.B.; Peleteiro, M.C.. "Epithelial Urinary Bladder Tumors From Cows With Enzootic Hematuria: Structural and Cell Cycle-Related Protein Expression". Vet Pathol 51 4 (2013): 749-754. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907451209&partnerID=MN8TOARS.
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  67. Remédio, L.; Carvalho, T.; Caiado, F.; Bastos-Carvalho, A.; Martins, D.; Duarte, A.; Yagita, H.; Dias, S.. "Context- and Cell-Dependent Effects of Delta-Like 4 Targeting in the Bone Marrow Microenvironment". PLoS ONE 7 12 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84871412471&partnerID=MN8TOARS.
    10.1371/journal.pone.0052450
  68. Caiado, F.; Carvalho, T.; Silva, F.; Castro, C.; Clode, N.; Dye, J.F.; Dias, S.. "The role of fibrin E on the modulation of endothelial progenitors adhesion, differentiation and angiogenic growth factor production and the promotion of wound healing". Biomaterials 32 29 (2011): 7096-7105. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960839631&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2011.06.022
  69. Borralho, P. M.; Simoes, A. E.; Gomes, S. E.; Lima, R. T.; Carvalho, T.; Ferreira, D. M.; Vasconcelos, M. H.; et al. "miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation". PLoS One 6 8 (2011): e23787-e23787. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052061782&partnerID=MN8TOARS.
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  70. Casalou, C.; Costa, A.; Carvalho, T.; Gomes, A.L.; Zhu, Z.; Wu, Y.; Dias, S.. "Cholesterol regulates VEGFR-1 (FLT-1) expression and signaling in acute leukemia cells". Molecular Cancer Research 9 2 (2011): 215-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951847932&partnerID=MN8TOARS.
    10.1158/1541-7786.MCR-10-0155
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    10.1371/journal.pone.0008980
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  74. Gomes, A.L.; Carvalho, T.; Serpa, J.; Torre, C.; Dias, S.. "Hypercholesterolemia promotes bone marrow cell mobilization by perturbing the SDF-1:CXCR4 axis". Blood 115 19 (2010): 3886-3894. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952978623&partnerID=MN8TOARS.
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  75. Carvalho, T.; Naydan, D.; Nunes, T.; Pinto, C.; Peleteiro, M. C.; Peleteiro, M.C.. "Immunohistochemical evaluation of vascular urinary bladder tumors from cows with enzootic hematuria". Vet Pathol 46 2 (2009): 211-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650870194&partnerID=MN8TOARS.
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Pré-impressão
  1. Andrea Spinazzola; Tânia Carvalho; Miguel Alexandre Ferreira Pinto; Mariana Marques-Reis; Andrés Gutiérrez-García; Davide Accardi; Eduardo Moreno. "Heterotypic competition between cancer cells and hepatocytes generates heterogeneous context-dependent phenotypes". 2024. https://doi.org/10.1101/2024.05.15.593526.
    10.1101/2024.05.15.593526
  2. Simões RV; Henriques RN; Olesen JL; Cardoso BM; Fernandes FF; Monteiro MA; Jespersen SN; Carvalho T; Shemesh N. "Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics". 2024. http://europepmc.org/abstract/PPR/PPR874813.
    10.1101/2024.06.23.600246
  3. Bruno Lopes-Bastos; Joana Nabais; Tânia Ferreira; Mounir El Maï; Malia Bird; Seniye Targen; Da Kang; et al. "Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish Melanoma". 2023. https://doi.org/10.1101/2023.03.24.534079.
    10.1101/2023.03.24.534079
  4. Pedro F. Marinho; Soraia L. Vieira; Tânia G. Carvalho; Maria C. Peleteiro; Thomas Hanscheid. "A novel and simple heat-based method eliminates the highly detrimental effect of xylene deparaffinization on acid-fast stains". 2022. https://doi.org/10.1101/2022.11.29.518155.
    10.1101/2022.11.29.518155
  5. Papotto PH; Yilmaz B; Pimenta G; Mensurado S; Cunha C; Fiala G; da Costa DG; et al. "Maternal ¿d T cells shape offspring pulmonary type-2 immunity in a microbiota-dependent manner". 2021. http://europepmc.org/abstract/PPR/PPR383119.
    10.1101/2021.08.13.456265
  6. Faria CC; Custódia C; Cascão R; Paisana E; Carvalho T; Pereira P; Roque R; et al. "Patient-derived models of brain metastases recapitulate the histopathology and biology of human metastatic cancers". 2020. http://europepmc.org/abstract/PPR/PPR245791.
    10.1101/2020.11.26.400036
Atividades

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023/02/01 - Atual Patologia Experimental - Curso de Dissecção de Roedores Mouse Dissection Workshop (Pós-Graduação) Fundação Champalimaud, Portugal