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Magda M Santana (PharmD, PhD) is a junior researcher interested in translational research in Neurosciences field. As undergraduate student, MMS was in the ranking of the 3% Best Students of Pharmaceutical Sciences. MMS finished her Integrated Master in Pharmaceutical Sciences (final classification 17/20), in 2008, and got her Doctoral degree in Pharmacy (Pharmacology and Pharmacotherapy) at University of Coimbra, Portugal, in 2013. In 2014, Magda was invited by Prof. Luis Pereira de Almeida to join the Vectors, Gene and Cell Therapy | Molecular Therapy of Brain disorders group and since then she has been focused her research in the development of biomarkers, pre-clinical models (iPSCs and rodents) and drug/gene therapies for MJD, in straight collaboration with other team members, international partners and pharmaceutical companies. In total, Magda has been part of the research team of 14 projects (including two international consortia: JPNDcoFund ESMI and ModelPolyQ). MS was awarded twice by the National Ataxia Foundation, the most prominent foundation supporting research in the US within ataxias field, with a post-doctoral grant (2016, $35 000) and with the SCA Young Investigator Award (2019), with a $50 000 budget attributed for developing a systems biology approach for biomarker discovery. Magda got international scientific experience as undergraduate student (Erasmus Program, London¿s University, UK), as PhD student (Dresden¿s University, Germany) and as post-doctoral researcher (training programs/courses in Luxembourg and Germany) and has actively participated in both national and international scientific meetings, being first or co-author of over 50 oral communications and 20 poster presentations. Magda is author/co-author of 14 papers/book chapters in peer-reviewed international journals, 15 conference abstracts with 342 citations (cumulative IF of 76, h-index of 9) and has/is supervisor of 1 PhD Student, 6 MSc students and several graduate/undergraduate students. Magda has been invited to give practical classes and lectures in graduate courses and programmes, for two academic years (2018-2020) she was responsible for support coordination of the Master in Pharmaceutical Biotechnology (Faculty of Pharmacy, University of Coimbra) and has participating in academic examining committees of MSc/PhD Thesis. Magda was also invited by NAF for grant evaluation. Magda engaged several scientific communication and knowledge transference public activities, such European Researcher´s night, Ciência Viva, Brain Awareness Week and Rare Disease¿s Day and is an active member of the SCA Global Young Investigator Initiative.
Identificação

Identificação pessoal

Nome completo
Magda Matos Santana

Nomes de citação

  • Santana, Magda M
  • Santana MM
  • Santana M
  • Magda M Santana

Identificadores de autor

Ciência ID
3E17-9ED3-1C8D
ORCID iD
0000-0003-4076-7516

Endereços de correio eletrónico

  • mmsantana@uc.pt (Profissional)
  • magda.santana@cnc.uc.pt (Profissional)

Websites

  • http://www.cnbc.pt/ (Académico)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2013 - 2018
Concluído
Pós-doutoramento (Pós-doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/07/27
Concluído
From Next Generation Sequencing to Translational Medicine in Neurological Disease Research (Outros)
Universitatsklinikum Tübingen Institut für Medizinische Genetik und angewandte Genomik, Alemanha
2016/06/10
Concluído
iPSC derivation and differentiation techniques (Outros)
Université du Luxembourg Luxembourg Centre for Systems Biomedicine, Luxemburgo
2016
Concluído
Statistics applied to laboratories felas (Outros)
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2013/12
Concluído
Investigador-coordenador para experimentação animal (Outros)
Direção-Geral de Alimentação e Veterinária, Portugal
2013/10/04
Concluído
Couse in Laboratory Animal Science - FELASA C (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/10/01 - 2013/07/26
Concluído
Farmácia (Doutoramento)
Especialização em Farmacologia e Farmacoterapia
Universidade de Coimbra Faculdade de Farmácia, Portugal
Louvor e distinção
2010/12/09
Concluído
Advanced course "The complex world of RNA" (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/05/21
Concluído
Advanced Course in Real-time PCR (Outros)
TATAA Biocenter, Suécia
2009/10/02
Concluído
Advanced course "Biostatistics" - PDBEB Programme (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009
Concluído
PhD Student - Internship - Neuroendocrinology (Outros)
Technische Universität Dresden, Alemanha

Universitätsklinikum Carl Gustav Carus, Alemanha
2002/10 - 2008/07
Concluído
Ciências Farmacêuticas (Mestrado integrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
17/20
2007
Concluído
Undergraduate training in Pharmaceutical Sciences - Erasmus program (Outros)
University College London Department of Pharmaceutical and Biological Chemistry, Reino Unido
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/15 - Atual Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2018/08/01 - 2020/07/31 Apoio à Coordenação do Mestrado em Biotecnologia Farmacêutica Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
Projetos

Bolsa

Designação Financiadores
2013 - 2015/09 Aging, Stress And Chronic Diseases: From Mechanisms to Therapeutics
CENTRO-07-ST24-FEDER-002006
Bolseiro de Investigação
FEDER (QREN), through Programa Mais Centro
2011 - 2014/08 iCALP - Identification of the physiological roles of calpains in the control of cell proliferation and migration in the central nervous system
Provided by PTCRIS: 112183
112183
Fundação para a Ciência e a Tecnologia, I.P.
2010 - 2013/07 Effect of caffeine and adenosine A2A receptors on stress response: role of adrenal gland modulation
Provided by PTCRIS: 108110
108110
Bolseiro de Investigação
Fundação para a Ciência e a Tecnologia, I.P.
2010 - 2012/09 The Neuropeptide Y (NPY) and Dipeptidyl-peptidase IV (DPPIV) as new promising targets on the adipose tissue regulation in obesity
Provided by PTCRIS: 102415
102415
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2007 - 2010/11 Neuropeptide Y in the retina: Why? What for?
Provided by PTCRIS: 73119
73119
Investigador
Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2019 - 2021 A systems approach to find a blood-based biomarker for Machado-Joseph Disease
SCA Young Investigator Award
Investigador responsável
National Ataxia Foundation, Estados Unidos
2016 - 2020/05/31 Advanced models of polyglutamine disorders (Huntington's disease, SCA3 and SCA7)
JPCOFUND/0005/2015
Investigador Pós-doutorado
EU Joint Programme Neurodegenerative Disease Research
2016 - 2020/05/29 JPND European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative
JPCOFUND/0001/2015-ESMI
Investigador Pós-doutorado
EU Joint Programme Neurodegenerative Disease Research
2010 - 2017 BrainHealth 2020 - Detecção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias
CENTRO-01-0145-FEDER-000008
Investigador
2015 - 2015 Caballeta@CNC-Study 3
n/a
Investigador Pós-doutorado
2013 - 2015 Aging, Stress And Chronic Diseases: From Mechanisms to Therapeutics
CENTRO-07-ST24-FEDER-002006
Investigador Pós-doutorado
2014 - 2014 Caballeta@CNC-Study 2
n/a
Investigador Pós-doutorado
2014 - 2014 Caballeta@CNC-Study 1
n/a
Investigador Pós-doutorado
2013 - 2014 iCALP - Identification of the physiological roles of calpains in the control of cell proliferation and migration in the central nervous system
PTDC/SAU-NMC/112183/2009
Investigador
2010 - 2013 Caloric restriction increases lifespan: role of NPY on autophagy
PTDC/SAU-FCF/099082/2008
Investigador
2009 - 2009 The Neuropeptide Y as a promising target on the adipose tissue regulation
n/a
Investigador
Produções

Publicações

Artigo em jornal
  1. Vinhas, Catarina Ana; Ferreira, Ana Cristina; Henriques, Carina; Silva, Ana Carolina; Vinhas, Catarina; Henriques, Daniel; Oliveira, Daniela; et al. "Uma viagem rara", PÚBLICO, 2020, https://www.publico. pt/2020/02/28/ciencia/fotogaleria/viagem-rara-400481.
Artigo em revista
  1. Santana, Magda M. "Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)". Autophagy (2021): https://pubmed.ncbi.nlm.nih.gov/33634751/.
    Publicado
  2. Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís. "Simple and Fast Size Exclusion Chromatography-based Protocol to Isolate Human Plasma-derived Extracellular Vesicles for Transcriptional Research". Molecular Therapy - Methods & Clinical Development (2020): http://dx.doi.org/10.1016/j.omtm.2020.07.012.
    10.1016/j.omtm.2020.07.012
  3. Wilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M; Warrenburg, Bart; et al. "Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice". EMBO Molecular Medicine 12 7 (2020): http://dx.doi.org/10.15252/emmm.201911803.
    10.15252/emmm.201911803
  4. Santana, Magda M.; Paixão, Susana; Cunha-Santos, Janete; Silva, Teresa Pereira; Trevino-Garcia, Allyson; Gaspar, Laetitia S.; Nóbrega, Clévio; et al. "Trehalose alleviates the phenotype of Machado-Joseph disease mouse models". Journal of Translational Medicine 18 1 (2020): http://dx.doi.org/10.1186/s12967-020-02302-2.
    10.1186/s12967-020-02302-2
  5. Santana, Magda M.; Rosmaninho-Salgado, Joana; Cortez, Vera; Pereira, Frederico C.; Kaster, Manuella P.; Aveleira, Célia A.; Ferreira, Marisa; et al. "Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress". European Neuropsychopharmacology 25 10 (2015): 1753-1766. http://dx.doi.org/10.1016/j.euroneuro.2015.06.013.
    Publicado • 10.1016/j.euroneuro.2015.06.013
  6. Kaster MP; Machado NJ; Silva HB; Nunes A; Ardais AP; Santana M; Baqi Y; et al. "Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress.". (2015): http://europepmc.org/abstract/med/26056314.
    10.1073/pnas.1423088112
  7. Aveleira CA; Botelho M; Carmo-Silva S; Pascoal JF; Ferreira-Marques M; Nóbrega C; Cortes L; et al. "Neuropeptide Y stimulates autophagy in hypothalamic neurons.". (2015): http://europepmc.org/abstract/med/25775546.
    10.1073/pnas.1416609112
  8. Faria, R.; Santana, M.M.; Aveleira, C.A.; Simões, C.; Maciel, E.; Melo, T.; Santinha, D.; et al. "Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress". Neuroscience 273 (2014): 1-11. http://dx.doi.org/10.1016/j.neuroscience.2014.04.042.
    Publicado • 10.1016/j.neuroscience.2014.04.042
  9. Santana MM; Ehrhart-Bornstein M; Cavadas C. "Progenitor cells in chromospheres: in response to Arthur S. Tischler.". (2013): http://europepmc.org/abstract/med/24282325.
    10.5966/sctm.2013-0062
  10. Rosmaninho-Salgado, Joana; Cortez, Vera; Estrada, Marta; Santana, Magda M.; Gonçalves, Alexandra; Marques, Ana Patrícia; Cavadas, Cláudia. "Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes". Neuropeptides 46 6 (2012): 359-366. http://dx.doi.org/10.1016/j.npep.2012.08.006.
    Publicado • 10.1016/j.npep.2012.08.006
  11. Santana MM; Chung KF; Vukicevic V; Rosmaninho-Salgado J; Kanczkowski W; Cortez V; Hackmann K; et al. "Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla.". (2012): http://europepmc.org/abstract/med/23197690.
    10.5966/sctm.2012-0022
  12. Rosmaninho-Salgado, Joana; Marques, Ana Patricia; Estrada, Marta; Santana, Magda; Cortez, Vera; Grouzmann, Eric; Cavadas, Cláudia. "Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-¿ expression". Peptides 37 1 (2012): 49-54. http://dx.doi.org/10.1016/j.peptides.2012.06.014.
    Publicado • 10.1016/j.peptides.2012.06.014
  13. Cortez, Vera; Santana, Magda; Marques, Ana Patrícia; Mota, Alfredo; Rosmaninho-Salgado, Joana; Cavadas, Cláudia. "Regulation of catecholamine release in human adrenal chromaffin cells by ß-adrenoceptors". Neurochemistry International 60 4 (2012): 387-393. http://dx.doi.org/10.1016/j.neuint.2011.12.018.
    Publicado • 10.1016/j.neuint.2011.12.018
  14. Sousa-Ferreira, Lígia; Álvaro, Ana Rita; Aveleira, Célia; Santana, Magda; Brandão, Inês; Kügler, Sebastian; Pereira de Almeida, Luís; Cavadas, Cláudia. "Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons". PLoS ONE 6 5 (2011): e19745. http://dx.doi.org/10.1371/journal.pone.0019745.
    Publicado • 10.1371/journal.pone.0019745
Capítulo de livro
  1. Nóbrega, Clévio; Simões, Ana Teresa; Duarte-Neves, Joana; Duarte, Sónia; Vasconcelos-Ferreira, Ana; Cunha-Santos, Janete; Pereira, Dina; et al. "Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis". In Advances in Experimental Medicine and Biology, 349-367. Springer International Publishing, 2018.
    Publicado • 10.1007/978-3-319-71779-1_18
  2. Nóbrega, Clévio; Simões, Ana Teresa; Duarte-Neves, Joana; Duarte, Sónia; Vasconcelos-Ferreira, Ana; Cunha-Santos, Janete; Pereira, Dina; et al. "Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis". In Advances in Experimental Medicine and Biology, 349-367. Springer International Publishing, 2018.
    10.1007/978-3-319-71779-1_18
  3. Santana, Magda M.; Rosmaninho-Salgado, Joana; Kaster, Manuella; Cortez, Vera; Cunha, Rodrigo A.; Cavadas, Cláudia. "Catecholamine Release Modulation by Adenosine Through A2a Receptors in Mouse Chromaffin Cells in Culture". In Catecholamine Research in the 21st Century, 244-245. Elsevier, 2014.
    10.1016/b978-0-12-800044-1.00215-4
  4. Santana, Magda M.; Cortez, Vera; Aveleira, Célia; Kaster, Manuella; Rosmaninho-Salgado, Joana; Cavadas, Cláudia. "Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland". In Catecholamine Research in the 21st Century, 205. Elsevier, 2014.
    10.1016/b978-0-12-800044-1.00184-7
Manual
  1. Magda M Santana; Gaspar, Laetitia; Kuhs, Sandra; Reetz, Kathrin; Infante, Jon; Klockgether, Thomas; Lima, Manuela; Hubener-Schmid, Jeannette; Pereira de Almeida, Luís. Standard operating proceadure (SOP): “ESMI - Manual for Biosample Collection". 2016.
Poster em conferência
  1. Henriques, Carina; Lopes, Miguel; Albuquerque, Patrícia Rosado; Rufino-Ramos, David; Gaspar, Laetitia; Lobo, Diana Duarte; Duarte, Sónia; et al.. "Extracellular vesicles-associated AAVs as new gene delivery vectors for the treatment of brain disorders". 2019.
  2. Henriques, Carina; Lopes, Miguel; Albuquerque, Patrícia Rosado; Rufino-Ramos, David; Gaspar, Laetitia; Lobo, Diana Duarte; Duarte, Sónia; et al. "Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain diseases". Trabalho apresentado em 5th GEIVEX Symposium, 2019.
  3. Santana, Magda M. "European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative (ESMI). JPco-fuND symposium, Faber J. "on behalf of ESMI Consortium"". Trabalho apresentado em JPco-fuND symposium, 2019.
  4. Santana, Magda M. "Blood biomarker quantification in SCA3 samples using the Neurology 4- PLEX A kit and the Simoa technology. International Ataxia Research Conference (IARC), Garcia-Moreno H et al. "on behalf of ESMI Consortium"". Trabalho apresentado em JPco-fuND symposium, 2019.
  5. Magda M Santana; Gaspar, Laetitia; Perfeito, Rita; Albuquerque, Patrícia Rosado; Rodrigues, Teresa; Girão, Henrique; Nobre, Rui Jorge; et al. "Optimization of a size exclusion chromatography protocol to isolate plasma-derived extracelular vesicles for transcriptional biomarkers research". Trabalho apresentado em International Society for Extracellular Vesicles Annual Meeting, 2018.
  6. Albuquerque, Patrícia Rosado; Magda M Santana; Nobre, Rui Jorge; Miranda, Catarina Oliveira; Lopes, SM; Ribeiro-Rodrigues, T; Girão, Henrique; Gomes, C; Pereira de Almeida, Luís. "Non-invasive delivery with hybrid extracelular vesicles for therapy of Machado Joseph-disease". Trabalho apresentado em International Society for Extracellular Vesicles Annual Meeting, 2018.
  7. Gaspar, Laetitia; Magda M Santana; Perfeiro, Rita; Albuquerque, Patrícia Rosado; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís. "Optimization of a size exclusion chromatography protocol to isolate plasma-derived extracelular vesicles for biomarker research". 2018.
  8. Laetitia, Gaspar; Magda M Santana; Perfeito, Rita; Albuquerque, Patrícia Rosado; Rodrigues, Teresa; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Magda. "Optimization of a size exclusion chromatography protocol to isolate plasma-derived extracelular vesicles for transcriptional analysis". 2018.
  9. Magda M Santana; Lopes, Sara M; Onofre, Isabel; Álvaro, Ana Rita ; Di Donato; Mendonça, N; Januário, Cristina; Pereira de Almeida, Luís. "Generation of Machado-Joseph disease induced pluripotent cell lines and isogenic controls using the CRISPR/Cas9 technology". Trabalho apresentado em International Ataxia Research Conference, 2017.
  10. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clélia; Paixão, Susana; Magda M Santana; Sena-Esteves, Miguel; Pereira de Almeida, Luís. "Non-invasive and allele-specific silencing of mutant ataxin-3 alleviates neuropathology and motor deficits of Machado-Joseph disease". Trabalho apresentado em International Ataxia Research Conference, 2017.
  11. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clélia; Magda M Santana; Sena-Esteves, Miguel; Pereira de Almeida, Luís; Fusco, Clelia; Paixão, Susana. "Non-invasive AAV9-mediated silencing of mutant ataxin-3 alleviates motor and neuropathological deficits in a transgenic mouse model of Machado-Joseph disease". Trabalho apresentado em 24th Annual Congress of European Society of Gene and Cell Therapy, 2016.
  12. Magda M Santana; Paixão, Susana; Silva, T.; Cunha-Santos, Janete; Cavadas, Claudia; Greif, Hagar; Pereira de Almeida, Luís. "Preclinical studies with Trehalose for Machado-Joseph Disease: in vitro and in vivo models". Trabalho apresentado em From NGS to Translational Medicine in Neurological Disease Research, 2016.
  13. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clélia; Paixão, Susana; Magda M Santana; Sena-Esteves, Miguel. "Silencing Spinocerebellar Ataxia Type 3 trough the systemic route". Trabalho apresentado em Ataxia Investigators Meeting (AIM), 2016.
  14. Gaspar, Laetitia; Álvaro, Ana Rita ; Carmo-Silva, Sara; Botelho, Mariana; Sousa-Ferreira, Lígia; Magda M Santana; Cavadas, Claudia. "Unravelling the role of NPY on the central circadian clock". Trabalho apresentado em XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia, XIII Reunião Anual do CNC, 2015.
  15. Magda M Santana; Paixão, Susana; Silva, T.; Cunha-Santos, Janete; Greif, Hagar; Pereira de Almeida, Luís. "Trehalose reverses disease phenotype of a transgenic mouse model of Machado-Joseph Disease". Trabalho apresentado em XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia, XIII Reunião Anual do CNC, 2015.
  16. Magda M Santana; Paixão, Susana; Trèvino, A; Silva, T.; Cunha-Santos, Janete; Greif, Hagar; Pereira de Almeida, Luís. "Trehalose alleviates behavioral and neuropathological features in a transgenic mouse model of Machado-Joseph disease". Trabalho apresentado em XIV Meeting of the Portuguese Society for Neurosciences, 2015.
  17. Magda M Santana; Nóbrega, Clévio David Rodrigues ; Nobre, Rui Jorge; Miranda, Catarina; Sousa-Ferreira, Ligia; Simões, Ana Teresa; Duarte, Sónia; et al. "Gene therapy approaches to investigate pathogenesis and disease modifying strategies for neurodegenerative diseases". Trabalho apresentado em Showcasing Portuguese Pharma Science:Advances in Discovery, Development and Manufacturing. Hovione and MIT Portugal Pharma Science Symposium, 2014.
  18. Magda M Santana; Vera, Cortez; Aveleira, Célia A.; Kaster, Manuella; Rosmaninho-Salgado, Joana; Cavadas, Claudia. "Chronic unpredictable stress induces catecholaminergic system changes in mouse adrenal gland". Trabalho apresentado em X International Catecholamine Symposium, 2012.
  19. Santana, Magda M; Rosmaninho-Salgado, Joana; Kaster, Manuella; Cortez, Vera; Cunha, Rodrigo A.; Cavadas, Claudia. "Catecholamine release modulation by Adenosine through A2A receptors in mouse chromaffin cell culture". Trabalho apresentado em X International Catecholamine Symposium, 2012.
  20. Rosmaninho-Salgado, Joana; Cortez, Vera; Gonçalves, M A; Magda M Santana; Marques, Ana Patrícia; Estrada, Marta; Cavadas, Claudia. "NPY cleaved by dipeptidyl-peptidase IV (DPPIV) induces preadipocytes differentiation". Trabalho apresentado em 10th International NPY-PYY-PP meeting, 2012.
  21. Santana, Magda M; Kaster, Manuella P.; Rosmaninho-Salgado J; Vicente, F; Cortez, Vera; Tomé, A; Cunha, Rodrigo A.; et al. "Adenosine A1 and A2A receptors in mouse adrenal gland: localization and catecholamine release modulation after chronic stress". Trabalho apresentado em 10th Symposium on catecholamines and other neurotransmitters in stress, 2011.
  22. Santana, Magda M; Rosmaninho-Salgado, Joana; Chung, Kuei-Fang; Vukicevic, Vladimir; Cortez, Vera; Bastos, Carlos A.; Mota, Alfredo; Ehrhart-Bornstein, Monika; Cavadas, Claudia. "Isolation and differentiation of progenitor cells from Human Adrenal Medulla". Trabalho apresentado em 6th international meeting of the Portuguese Society for Stem Cells and Cell Therapies”, 2011.
  23. Rosmaninho-Salgado, Joana; Marques, Patricia; Cortez, Vera; Santana, Magda; Santos, J.; Cavadas, Claudia. "The dual role of hypoxia on adipogenesis". Trabalho apresentado em The Obesity Society’s 2010 Annual Scientific Meeting, 2010.
  24. Rosmaninho-Salgado, Joana; Marques, Patricia; Santana, Magda M; Grouzmann, Eric; Cavadas, Claudia. "NPY plays an important role in adipose tissue formation regulating adipocytes proliferation and differentiation through different mechanisms". Trabalho apresentado em Join Meeting: Biology of Adipose Tissue and Neuronal Control of appetite, Metabolism and Weight (J4), 2010.
  25. Rosmaninho-Salgado, Joana; Santana, Magda M; Grouzmann, Eric; Cavadas, Claudia. "The effect of dipeptidylpeptidase IV (DPPIV) on the proliferation and differentiation on 3T3L1 preadipocyte murine cell line". Trabalho apresentado em Stress, Drug Addiction and Eating Disorders, 2009.
Resumo em conferência
  1. Nobre, Rui Jorge; Saraiva, Joana; Santana, Magda M; Fusco, Clelia; Paixão, Susana; Miranda, Catarina; Petrella, Lorena; et al. "Allele-Specific AAV-Based Silencing of Mutant Ataxin-3 Alleviates Neuropathology and Motor Deficits in Spinocerebellar Ataxia Type 3". Trabalho apresentado em 23rd Annual Meeting of the American Society for Gene and Cell Therapy, Boston, 2020.
    Publicado
  2. Santana, Magda M; Silva, Patrick; Gaspar, Laetitia; Henriques, Carina; Ribeiro, Joana; Cunha, Inês; Nobre, Rui Jorge; Januario, Cristina; Pereira de Almeida, Luis. "miRNA expression profile of plasma-derived extracellular vesicles distinguishes Machado-Joseph Disease patients from controls". Trabalho apresentado em 23rd Annual Meeting of the Portuguese Society of Human Genetics, Coimbra, 2020.
    Publicado
  3. Bras, A; Cunha, Ines; Silva, Patrick; Santana, Magda M; Ribeiro, Joana A; Pereira de Almeida, Luis; Januario, Cristina. "Characterization of a Portuguese cohort of Machado-Joseph disease: besides ataxia". Trabalho apresentado em 5th Congress of the European Academy of Neurology, Oslo, 2019.
    Publicado
  4. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clelia; Paixao, Susana; Santana, Magda M; Miranda, Catarina; Petrella, Lorena; et al. "A miRNA-based gene therapy approach to knock-down mutant ATXN3: Alleviation of Machado-Joseph disease phenotype in two mouse models upon two routes of administration". Trabalho apresentado em 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
    Publicado
  5. Santana, Magda M; Silva, Patrick; Ribeiro, Joana; Cunha, Inês; Gaspar, Laetitia; Januario, Cristina; Pereira de Almeida, Luis. "Characterization and follow-up of the Coimbra cohort of Machado-Joseph disease patients". Trabalho apresentado em 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019.
    Publicado
  6. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clelia; Paixao, Susana; Santana, Magda M; Petrella, Lorena; Sereno, Jose; et al. "Non-invasive allele-specific silencing therapy and biomarkers for Machado-Joseph disease". Trabalho apresentado em Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, 2018.
    Publicado
  7. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clelia; Paixao, Susana; Santana, Magda M; Petrella, Lorena; Sereno, Jose; et al. "Non-Invasively Silencing and Monitoring Machado-Joseph Disease". Trabalho apresentado em 21st Annual Meeting of the American Society of Gene and Cell Therapy, Chicago, 2018.
    Publicado
  8. Magda M Santana; Paixão, Susana; Silva, Teresa; Cunha-Santos, Janete; Cavadas, Claudia; Greif, Hagar; Pereira de Almeida, Luís. "Trehalose reverses the phenotype of Machado-Joseph disease models. International Journal of Clinical Neurosciences and Mental Health". Lisboa, 2016.
    Publicado
  9. Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clelia; Paixão, Susana; Magda M Santana; Sena-Esteves, Miguel; Pereira de Almeida, Luís. "Non-invasive AAV9-mediated silencing of mutant ataxin-3 alleviates motor and neuropathological deficits in a transgenic mouse model of Machado-Joseph disease, Human Gene Therapy". Florence, 2016.
  10. Domingues, M.R.; Faria, R.; Simoes, C; Aveleira, C; Santana, Magda M; Cavadas, C. "Alteration in brain phospholipid profile after chronic stress: a lipidomic study". 2012.
    Publicado
  11. Rosmaninho-Salgado, Joana; Marques AP; Magda M Santana; Cavadas, Claudia. "A hipóxia induz a acumulação lipidica e a disfunção da homeostase do adipócito, Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo". 2011.
    Publicado
  12. Rosmaninho-Salgado, Joana; Marques, Patrícia; Magda M Santana; Santos, J; Cavadas, Claudia. "The Dual Effect of Hypoxia on Adipogenesis, Obesity". 2010.
    Publicado
  13. Rosmaninho-Salgado, Joana; Marques, Patricia; Cortez, V; Magda M Santana; Santos, J; Cavadas, Claudia. "Does the hypoxia-mimetic agent, COCl2, have a dual effect on adipogenesis?, Diabetes, obesity and metabolism". 2010.
    Publicado
  14. Rosmaninho-Salgado, Joana; Magda M Santana; Grouzmann, E; Cavadas, Claudia. "Dipeptidyl-peptidase (DPPIV) stimulates the proliferation and differentiation of 3T3-L1 pre-adicopcyte murine cell line, Obesity". 2009.
    Publicado
  15. Rosmaninho-Salgado, Joana; Magda M Santana; Faneca, Henrique; Grouzmann, E; Cavadas, Claudia. "The increase of preadipocyte proliferation induced by DPPIV is inhibited by vildagliptin, Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo". 2009.
    Publicado
Tese / Dissertação
  1. Magda M Santana. "Stress, depression and adrenal gland: an insight into the adrenal medullary catecholaminergic system. Dissertation". Doutoramento, Universidade de Coimbra Faculdade de Farmácia, 2013. http://hdl.handle.net/10316/23791.

Outros

Outra produção
  1. Carlo Wilke; Eva Haas; Kathrin Reetz; Jennifer Faber; Hector Garcia-Moreno; Magda M. Santana; Bart van de Warrenburg; et al. 2019. Neurofilaments as blood biomarkers at the preataxic and ataxic stage of spinocerebellar ataxia type 3: a cross-species analysis in humans and mice. https://doi.org/10.1101/19011882.
    10.1101/19011882
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/02/19 Phenotypic characterization of neuronal cultures derived from Machado Joseph-Disease induced pluripotent stem cells. LI Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02/19 Phenotypic characterization of a relevant model of Machado-Joseph disease: the YAC-MJD mouse model LI Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02/19 European Spinocerebellar Ataxia type 3/ Machado-Joseph Disease initiative: clinical overview of the Coimbra's cohort LI Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02/18 Brain micrornas in plasma-derived extracellular vesicles as potential biomarkers for Machado-Joseph Disease. LI Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2021/02/18 Identification of dysregulated mirnas in human induced pluripotent stem cell-based models of Machado-Joseph Disease: one step closer to a therapeutic approach? LI Annual Meeting of the Portuguese Society of Pharmacology
Portuguese Society of Pharmacology (Lisboa, Portugal)
2019/12 Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain disorders 1st Annual Meeting in Pharmaceutical Sciences
(Coimbra, Portugal)
2019/11 Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain diseases 5th GEIVEX Symposium
(Granada, Espanha)
2019/11 miRNA expression profile of plasma-derived extracellular vesicles distinguishes Machado-Joseph Disease patients from controls 23rd Annual Meeting, Portuguese Society of Human Genetics
(Coimbra, Portugal)
2019/05 Characterization and follow-up of the Coimbra cohort of Machado-Joseph Disease Patients 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
2019/05 A miRNA-based gene therapy approach to knock-down mutant ATXN3: alleviation of Machado-Joseph disease phenotype in two mouse models upon two routes of administration 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
2019/03 Serum neurofilaments in SCA3. 1st SCA Global Conference, Wilke C et al. "on behalf of ESMI Consortium" 1st SCA Global Conference,
(las vegas, Estados Unidos)
2019/02 Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain diseases XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia clínica, XVIII Reunião de toxicologia
(Porto, Portugal)
2019/02 Characterization of a trial-ready cohort of Machado-Joseph disease patients: status update XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia clínica, XVIII Reunião de toxicologia
(Porto, Portugal)
2019 Blood biomarker quantification in SCA3 samples. 1st SCA Global Conference, Garcia-Moreno H et al. "on behalf of ESMI consortium" 1st SCA Global Conference,
(las vegas, Estados Unidos)
2019 Blood biomarker quantification in SCA3 samples using the Neurology 4-PLEX A kit and the Simoa technology. International Ataxia Research Conference (IARC), Garcia-Moreno H et al. "on behalf of ESMI Consortium" International Ataxia Research Conference (IARC)
2019 European Spinocerebellar Ataxia Type 3/Machado- Joseph Disease Initiative (ESMI). JPco-fuND symposium, Klockgether T. "on behalf of ESMI Consortium"
2018/05 ESMI Biomarkers studies: status and research plan 3rd JPND-ESMI meeting
ESMI consortium (Ponta Delgada, Azores, Portugal)
2018/05 Non-invasive brain delivery with hybrid extracellular vesicles (EVs) for therapy of Machado-Joseph disease (MJD) International Society for Extracellular Vesicles Annual Meeting
(Barcelona, Espanha)
2018/02 Hybrid vesicles: a promising therapeutic approach for Machado-Joseph disease. 1st Meeting on Vesicle Biology
(Coimbra, Portugal)
2018/02 Generation of a Machado-Joseph disease isogenic control induced pluripotent stem cell line XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia clínica, XVII Reunião de toxicologia
(Lisboa, Portugal)
2018/02 Characterization of a trial-ready cohort of Machado-Joseph disease patients XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia clínica, XVII Reunião de toxicologia
(Lisboa, Portugal)
2018/02 Non-invasive and allele specific gene silencing therapy for Machado Joseph disease and a biomaker to monitor the therapeutic response XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia clínica, XVII Reunião de toxicologia
(Lisboa, Portugal)
2018/01 Exosomes: tiny vesicles with great potential for MJD treatment XII Spanish-Portuguese Conference on Controlled Drug Delivery.
(Coimbra, Portugal)
2017/07 Generation of iPSCs for Machado Joseph Disease/Spinocerebellar ataxia type 3 2nd JPND-ModelPolyQ meeting
(Strasbourg, França)
2017/05 Workpackge 4 – Biomarkers for Machado Joseph-disease 2nd JPND-ESMI meeting
(Coimbra, Portugal)
2017/05 Non-invasive silencing of mutant ataxin-3 alleviates motor and neuropathological deficits in a transgenic mouse model of Machado-Joseph disease Congresso Nacional da Sociedade Portuguesa de Neurociências (SPN)
(Braga, Portugal)
2017/04 Silencing Spinocerebellar Ataxia Type 3 trough the systemic route Congresso Nacional da Sociedade Portuguesa das Doenças do Movimento (SPDMov)
(Ofir, Portugal)
2017/02 Silencing MJD trough the systemic route XLVII Reunião da Sociedade Portuguesa de Farmacologia, XXXV Reunião de Farmacologia clínica, XVI Reunião de toxicologia
(Coimbra, Portugal)
2016/11 Non-invasive and viral-mediated silencing of mutant ataxin-3 alleviates motor and neuropathological deficits in a transgenic mouse model of Machado-Joseph disease 20ª Reunião Anual da Sociedade Portuguesa de Genética Humana (SPGH)
(Coimbra, Portugal)
2016/03 Trehalose reverses the phenotype of Machado-Joseph disease models 10th World Congress on Controversies in Neurology (CONy)
(Lisboa, Portugal)
2016/02 Trehalose reverses disease phenotype in both in vitro and in vivo models of Machado-Joseph disease transgenic mice XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXIV Reunião anual de Farmacologia Clínica e XV Reunião de Toxicologia
(Porto, Portugal)
2016/02 Silencing Machado-Joseph disease/Spinocerebellar ataxia type 3 through the systemic route XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXIV Reunião anual de Farmacologia Clínica e XV Reunião de Toxicologia
(Porto, Portugal)
2016/02 The role of NPY on the hypothalamic circadian clock genes XLVI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXIV Reunião anual de Farmacologia Clínica e XV Reunião de Toxicologia
(Porto, Portugal)
2014/02 Role of chromaffin progenitor cells on adrenal medulla response to stress XLIV Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXII Reunião anual de Farmacologia Clínica e XIII Reunião de Toxicologia
(Coimbra, Portugal)
2013/02 Chronic unpredictable stress, as a model of depression, induces changes in mouse adrenal gland XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXI Reunião anual de Farmacologia Clínica e XII Reunião de Toxicologia
(Porto, Portugal)
2012/12 Chromaffin progenitor cells: Isolation, characterization, differentiation and putative role on adrenal medulla adaptation to stress X CNC meeting
(Coimbra, Portugal)
2012/09 Chronic unpredictable stress induces catecholaminergic system changes in mouse adrenal gland X International Catecholamine Symposium
(Pacific Grove, CA, Estados Unidos)
2012/02 Characterization and differentiation of progenitor cells from normal adult human adrenal medulla XLII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXX Reunião anual de Farmacologia Clínica e XI Reunião de Toxicologia
(Lisboa, Portugal)
2011/02 Adenosine A1 and A2A receptors in mouse adrenal gland: localization and catecholamine release modulation XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião anual de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011/02 Hypoxia has dual effects on adipocyte differentiation: relevance on obesity XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião anual de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011/02 Gliptins inhibit lipid accumulation in a murine pre-adipocyte cell line XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião anual de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011/02 Hypothalamic progenitor cells differentiate into functional neurons ) XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião anual de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2011/02 ß-adrenergic receptors activation in human adrenal chromaffin cells: role on catecholamines release XLI Reunião Anual da Sociedade Portuguesa de Farmacologia, XXIX Reunião anual de Farmacologia Clínica e X Reunião de Toxicologia
(Coimbra, Portugal)
2010/12 Modulation of Neuropeptide Y in the adult hypothalamus and hypothalamic neurospheres – role on feeding behavior VIII CNC Meeting
(Coimbra, Portugal)
2010/11 Does the hypoxia-mimetic agent, CoCl2, have a dual effect on adipogenesis 1 st International Diabetes and Obesity Forum
(Atenas, Grécia)
2010/11 The role of selective inhibitor dipeptidyl-peptidase IV (DPPIV) on the adipogenesis of 3T3-L1 pre-adipocyte murine cell line 14º Congresso Português de Obesidade
(Coimbra, Portugal)
2010/05 The role of hypoxia on pre-adipocyte proliferation and adipocyte differentiation Survival or Death as a Matter of Fat
(Coimbra, Portugal)
2010/01 NPY plays na important role in adipose tissue formation regulating adipocytes proliferation and differentiation through different mechanisms Neuronal Control of Appetite, Metabolism and Weight
(Keystone, Colorado, Estados Unidos)
2009/12 Isolation and characterization of progenitor cells from normal adult human adrenal medulla ) XL Reunião Anual da Sociedade Portuguesa de Farmacologia, XXVIII Reunião anual de Farmacologia Clínica e IX Reunião de Toxicologia
(Porto, Portugal)
2009/10 Dipeptidylpeptidase IV (DPPIV) stimulates the proliferation and differentiation of 3T3L1 preadipocyte murine cell line Obesity 2009 - 27th Annual Scientific Meeting of the Obesity Society
(Washington DC, Estados Unidos)
2009/01 The increase of pre-adipocyte proliferation induced by dipeptidyl-peptidase IV (DPPIV) is inhibited by vildagliptine Encontro Nacional da Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolism
(Vilamoura, Portugal)
2009 The neuropeptide Y cleaved by dipeptidylpeptidase IV (DPPIV) producing endogenous NPY Y2 agonist, induces preadipocytes proliferation and differentiation XL Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/10/18 - Atual Tackling CANcer STEM CELLs: a challenge and an opportunity to advance in anti-cancer therapy
Orientador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020 - Atual The Role of The Immune System in Polyglutamine Diseases
Orientador
Master in Pharmaceutical Biotechnology
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - Atual Machado-Joseph Disease Comorbidities and Symptomatic Treatments: a large cohort analysis
Orientador
Master in Pharmaceutical Biotechnology
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020 - Atual Hepatite autoimune: um estudo na população portuguesa com dados reportados pelos doentes
Orientador
Mestrado em Biotecnologia Farmacêutica (Mestrado)
2019/11/19 - Atual BrainHealth 2020 : Deteção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias
Coorientador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/06/01 - Atual BrainHealth 2020 : Deteção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias
Orientador
2019 - 2020/12 Brain-enriched plasma-derived extracellular vesicles as biomarkers for Machado-Joseph disease
Orientador de Maria Manuel Martins Pinto
Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2020 Phenotypic characterization of cellular and animal models of Machado-Joseph disease
Orientador
Biotecnologia Farmacêutica
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/03 - 2017/07 Characterization of healthy controls and MJD patient's derived induced pluripotent stem cells (iPSc)
Coorientador de Rachele di Donato
Medical, Veterinary and Pharmaceutical Biotechnology (Mestrado)
Università degli Studi del Sannio, Itália

Università degli Studi di Foggia, Itália
2016/01 - 2016/07 Clarifying the Mechanism of Action of Trehalose on Alleviating Machado-Joseph Disease
Coorientador de Allyson Trèvino
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra, Portugal
2015/05 - 2015/07 Estudos pré-clínicos em modelos animais com a doença de Machado-Joseph
Orientador de Patrícia Ines Pires dos Santos
Ciências Biomédicas (Licenciatura/Bacharelato)
Universidade do Algarve, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2018 - Atual Rare diseases day@CNC (2018/02/28)
2020 - 2020 Machado-Joseph Disease: From Laboratory to Society - Rare Disease Day 2020, Centre for Neuroscience and Cell Biology. Coimbra, Portugal. February 2020. (2020/02/28)
Encontro (Coorganizador)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/05/22 - 2017/05/23 2nd JPND ESMI meeting. CNC, May 22-23, Coimbra, Portugal. 2017 (2017 - 2017)
Encontro (Coorganizador)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016 - 2016 1st Symposium on aging research. CNC. Sep 30, Coimbra, Portugal. 2016 (2016 - 2016) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016 - 2016 1st JPND ModelPolyQ meeting. CNC, Jul 4-5, Coimbra, Portugal. 2016 (2016 - 2016)
Encontro
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016 - 2016 1st International Symposium Brain Without Borders. November 18-19, Coimbra, Portugal. 2016 (2016 - 2016)
Simpósio (Membro da Comissão Organizadora)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2018 - Atual European Researchers' Night 2018 European Researchers' Night 2018
2018 - Atual Brain Awareness Week

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2020 The role of ageing in polyglutamine-induced neurodegeneration: a study in Machado-Joseph Disease models Dina Maria da Silva Rodrigues Pereira (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 Processos Biotecnológicos Aplicados ao Transplante de Órgãos Sara Henrique Silvestre Neves Jacinto (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 CERVICAL CANCER SCREENING: SELF-SAMPLING AS A COMPLEMENT TO THE CONVENTIONAL METHOD Sara da Graça Marques Pereira (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 A DIFFERENT PERSPECTIVE OF CIRCULATORY BIOMARKERS IN NEURODEGENERATIVE DISEASES: FOCUS ON SERUM HIGH MOLECULAR WEIGHT FRACTION Miguel Maria Varandas Anão Rosado (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 Histological and Morphological Analysis of Developing Neuronal Precursors Derived from Human iPS Cells Daniela Catarina Gaspar Santos (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/09/29 Novos Sistemas para Penetração da Barreira Hematoencefálica: das Microbolhas à Focagem de Ultrassons Luís Miguel Lopes Martinho (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2019 - Atual National Ataxia Foundation - Evaluation panel of Scientific calls

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2019 - 2020 Pharmacological screening Farmácia Biomédica (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2020 Drug pre-clinical development Farmácia Biomédica (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/11/13 - 2019/11/13 Curso Ataxias hereditárias e paraparésias espásticas: da biologia molecular ao tratamento (Diploma de especialização)
2018/05/08 - 2018/05/08 Biomarkers Biologia Experimental e Biomedicina (Doutoramento) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2018/04/28 - 2018/04/28 Induced Pluripotent Stem Cells: biobank and disease modelling Biotecnologia Farmacêutica (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/06/09 - 2017/06/09 Biomarcadores em doença neurodegenerativa: oportunidades e dificuldades Farmacologia Aplicada (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/04/08 - 2017/04/08 Induced Pluripotent Stem Cells: biobank and disease modelling Biotecnologia Farmacêutica (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/12/06 - 2016/12/06 Genetic aproaches to fight neurodegenerative diseases Neurociências Instituto de Medicina Molecular João Lobo Antunes, Portugal
2016/06/25 - 2016/06/25 Elaboração de um plano de estudo em ensaios pré-clínicos Farmacologia Aplicada (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2013 - 2014 Human anatomy and physiology Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2010 - 2013 Histologia e Embriologia Humana Ciências Farmacêuticas (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2011 - 2011/01/31 Stem cells in adult adrenal medulla…or not? Biologia Experimental e Biomedicina Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2009 - 2010 Screening Farmacológico Farmácia Biomédica (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2019/11/14 Entrevista no âmbito do curso "Ataxias hereditárias e paraparésias espásticas: da biologia molecular ao tratamento", no Congresso de Neurologia 2019. Correio SPN

Membro de associação

Nome da associação Tipo de participação
2020/10/19 - Atual SCA Global Young Investigator Initiative - http://ataxia-global-initiative.net/young-investigator-initiative-yii/yii/ Founder member - in collaboration with Jennifer Faber and Heike Jacobi
2018/04/02 - Atual SCA Global Initiative - http://ataxia-global-initiative.net/sca-global/ Member
2018/01/01 - Atual Neurosciences Portuguese Society
Distinções

Prémio

2019 NAF Young Investigador SCA 2019
National Ataxia Foundation, Estados Unidos
2017 Basic Science Award 2016 with the work: Silencing Spinocerebellar Ataxia Type 3 through the systemic route." (co-authorship)
2016 Best Poster Award with the work: Preclinical studies with Trehalose for MJD: in vitro and in vivo models¿.
2016 NAF Post-doc Fellowship Award 2016
2016 Clinical Investigation Award 2016 with the work: Non-invasive and viral-mediated silencing of mutant ataxin-3 alleviates motor and neuropathological deficits in a transgenic mouse model of Machado-Joseph disease¿(co-authorship)
2014 Pergunta-me Ciência
Ciência Viva, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013 Poster award for the presentation “NPY cleaved by dipeptidyl-peptidase IV (DPPIV) induces preadipocytes differentiation.”Authors: Rosmaninho-Salgado J, Cortez V, Gonçalves MA, Santana M, Marques AP, Estrada M, Cavadas C.
2010 2nd prize - Research potential in the field of obesity with project untitled : The Neuropeptide Y as a promising target on the adipose tissue regulation¿ (member of the researcher team)
2010 3% best students of Pharmaceutical Sciences of the University of Coimbra - Academic year 2007/2008
Universidade de Coimbra, Portugal
2008 3% best students of Pharmaceutical Sciences of the University of Coimbra - Academic year 2006/2007
Universidade de Coimbra, Portugal
2007 3% best students of Pharmaceutical Sciences of the University of Coimbra - Academic year 2005/2006
Universidade de Coimbra, Portugal

Outra distinção

2008 PhD Fellowship
Fundação para a Ciência e a Tecnologia, Portugal