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Sofia Mendes Saraiva is currently Technical-Scientific Coordinator at the Polytechnique Institute of Guarda (IPG) in the functional area of Health and Welfare in the field of Health Care Support Technologies and is a researcher at the Center of Potential and Innovation of Natural Resources (CPIRN) of the IPG. She is an ambassador of the Young Scientist Committee of the Controlled Release Society (YSC) and member of the Organization Committee of Pint of Science Portugal (Guarda). Sofia holds a doctor degree in Drug Research and Development (International degree, Cum Laude) by the University of Santiago de Compostela (Spain), since 2019. She developed her PhD through a Marie Sklodowska-Curie scholarship, on "Polymeric nanocapsules for the ocular delivery of siRNA", under the supervision of Professor María José Alonso. This project was developed within the European consortium "Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases" (H2020-MSCA-ITN-2014, Grant ID 642028). During this period, she was also a visiting pre-doctoral researcher at the group of Professor Francesco Nicotra and Professor Laura Russo (University of Milan, Italy) and at the biotechnology company Sylentis S. A (Madrid, Spain). During her PhD, Sofia also participated in the 7th edition of the entrepreneurship program YUZZ Jóvenes con ideas, funded and promoted by Banco Santander. The project Sadvia, developed by Sofia Dr Matilde Durán was selected among the different Spanish projects and awarded the prize of "YUZZ Mujer 2016". From 2019 to 2021 she was a post-doctoral researcher at the Nano-Oncology and Translational Therapeutics Unit, directed by Dr de la Fuente, at the Instituto de Investigación Sanitária de Santiago de Compostela (IDIS, Spain). Herein she worked on different projects regarding the development of nanotechonology-based therapeutics for the management of cancer, cell senescence and skin conditions, in collaboration with national and international research groups. In addition, she was involved in the European project "Photoactivable nanoparticles to immunostimulate the tumor microenvironment in pancreatic cancer" (ERA-NET Euronanomed 3, Grant ID: JTC2018-041). Sofia has participated in different national and international workshops, congresses and seminars lectured by relevant names in the field of nanotechnology, biomedicine and entrepreneurship. Currently, as a researcher at the CPIRN-IPG since the end of 2021, her research interests focus on the development of novel nanotherapeutics, based on natural products, for the management ocular and skin conditions.
Identificação

Identificação pessoal

Nome completo
SOFIA MENDES SARAIVA

Nomes de citação

  • Saraiva, Sofia M
  • Saraiva, Sofia Mendes

Identificadores de autor

Ciência ID
3511-F6AC-06F0
ORCID iD
0000-0001-8849-804X
Researcher Id
AAY-1488-2021
Scopus Author Id
57193545165

Endereços de correio eletrónico

  • sofiasaraiva@ipg.pt (Profissional)

Websites

  • https://www.linkedin.com/in/sofia-m-saraiva-93b55098/ (Profissional)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C1)
Galego Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B2)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2015/10 - 2019/11
Concluído
Drug research and development (Doctor of Philosophy)
Universidade de Santiago de Compostela, Espanha
"Polymeric nanocapsules for the ocular delivery of siRNA" (TESE/DISSERTAÇÃO)
Sobresaliente, Cum Laude
2012 - 2014
Concluído
Bioquímica (Mestrado integrado)
Universidade da Beira Interior, Portugal
"Novel therapeutic approaches for skin regeneration" (TESE/DISSERTAÇÃO)
2008 - 2012
Concluído
Bioquímica (Licenciatura)
Universidade da Beira Interior, Portugal
2010/02/10 - 2010/04/19
Concluído
Manipulação de Imagem (Outros)
Centro Tecnológico das Indústrias Têxtil e do Vestuário de Portugal, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2021/09/01 - Atual Investigador Coordenador (carreira) (Investigação) Instituto Politécnico da Guarda, Portugal
2019/12 - 2021/08 Investigador Contratado (Investigação) Instituto de Investigación Sanitaria de Santiago de Compostela, Espanha
2018/06 - 2018/08 Investigador visitante (Investigação) Sylentis S.A., Espanha
2015/09 - 2018/08 Investigador Contratado (Investigação) Universidade de Santiago de Compostela, Espanha
Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2017/10 - 2017/12 Investigador visitante (Investigação) Università degli Studi di Milano-Bicocca, Itália
2015/01 - 2015/05 Investigador (Investigação) Universidade de Trás-os-Montes e Alto Douro, Portugal
Projetos

Bolsa

Designação Financiadores
2015 - 2019/11/29 Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases (NABBA)
642028
Bolseiro de Doutoramento
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha

Universidade de Santiago de Compostela - Campus Vida, Espanha
Horizon 2020
Concluído

Projeto

Designação Financiadores
2019 - 2021/08/31 PHOTOACTIVABLE NANOPARTICLES TO IMMUNOSTIMULATE THE TUMOUR MICROENVIRONMENT IN PANCREATIC CANCER
JTC2018-041
Investigador Pós-doutorado
Instituto de Investigación Sanitaria de Santiago de Compostela, Espanha
Horizon 2020
Em curso
2015 - 2019/11/29 Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases (NABBA)
642028
Bolseiro de Doutoramento
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha

Universidade de Santiago de Compostela - Campus Vida, Espanha
Horizon 2020
Concluído
Produções

Publicações

Artigo em revista
  1. Jatal, Raneem; Mendes Saraiva, Sofia; Vázquez-Vázquez, Carlos; Lelievre, Eric; Coqueret, Olivier; López-López, Rafael; de la Fuente, Maria. "Sphingomyelin nanosystems decorated with TSP-1 derived peptide targeting senescent cells". International Journal of Pharmaceutics (2022): 121618. http://dx.doi.org/10.1016/j.ijpharm.2022.121618.
    10.1016/j.ijpharm.2022.121618
  2. Masoumi, Farimah; Saraiva, Sofia Mendes; Bouzo, Belén L; López-López, Rafael; Esteller, Manel; Díaz-Lagares, Ángel; de la Fuente, Maria. "Modulation of Colorectal Tumor Behavior via lncRNA TP53TG1-Lipidic Nanosystem". Pharmaceutics 13 9 (2021): 1507-1507. http://dx.doi.org/10.3390/pharmaceutics13091507.
    10.3390/pharmaceutics13091507
  3. Saraiva, Sofia Mendes; Gutiérrez-Lovera, C; Martínez-Val, J; Lores, S; Bouzo, Belén L; Díez-Villares, S; Alijas, S; et al. "Edelfosine nanoemulsions inhibit tumor growth of triple negative breast cancer in zebrafish xenograft model". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-87968-4.
    10.1038/s41598-021-87968-4
  4. Nunes, Sílvia Cristina; Saraiva, Sofia Mendes; Pereira, Rui F. P.; Silva, Maria Manuela ; Carlos, Luís D; Almeida, P; Gonçalves, M C; Ferreira, Rute A S; de Zea Bermudez, Verónica. "Luminescent ¿-Carrageenan-Based Electrolytes Containing Neodymium Triflate". Molecules (2019): http://dx.doi.org/10.3390/molecules24061020.
    10.3390/molecules24061020
  5. Céu M. Sousa; Saraiva, Sofia Mendes; Macedo, Helena; Coelho, Paulo Jorge dos Santos. "Grey colouring thermally reversible photochromic 1-vinylidene-naphthofurans". Dyes and Pigments (2017): http://dx.doi.org/10.1016/j.dyepig.2017.02.027.
    10.1016/j.dyepig.2017.02.027
  6. Saraiva, Sofia Mendes; Castro-López, Vanessa; Pañeda, Covadonga; Alonso, M J. "Synthetic nanocarriers for the delivery of polynucleotides to the eye". European Journal of Pharmaceutical Sciences (2017): http://dx.doi.org/10.1016/j.ejps.2017.03.001.
    10.1016/j.ejps.2017.03.001
  7. Saraiva, Sofia Mendes; Sónia P. Miguel; Ribeiro, Maximiano; Coutinho, Paula; Correia, I.J.. "Synthesis and characterization of a photocrosslinkable chitosan-gelatin hydrogel aimed for tissue regeneration". RSC Advances (2015): http://dx.doi.org/10.1039/c5ra10638a.
    10.1039/c5ra10638a
  8. Silva, Edgar; Saraiva, Sofia Mendes; Sónia P. Miguel; Correia, I.J.. "PVP coated silver nanoparticles showing antifungal improved activity against Dermatophytes". Journal of Nanoparticle Research (2014):
    10.1007/s11051-014-2726-2
Poster em conferência
  1. Saraiva, Sofia Mendes; Abal Sanisidro, M; Lores, S; Lopez, JM; Cobo, AG; Rodriguez, LC; Arribas, JL; López-López, Rafael; de la Fuente, Maria. "PANIPAC - photoactivable nanoparticles to immunostimulate the tumor microenvironment in Pancreatic Cancer". Trabalho apresentado em III Young Researchers Meeting from CIBERONC, 2020.
  2. Saraiva, Sofia Mendes; Alonso, María José. "Double-layered protamine nanocapsules as iRNA delivery systems". Trabalho apresentado em 2nd SPLC-CRS Young Scientists Meeting, 2019.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/12/15 Nanotechnology and drug delivery - Finding the true nanovehicle As 4 estações da ciência do IPG
(Guarda, Portugal)
2017/05/18 Meeting entrepreneurship and science - SADVIA Scientific Advisers II International Congress in Health Sciences Research towards Innovation and entrepreneurship
Universidade da Beira Interior (Covilhã, Portugal)
2015/04/15 PVP-coated silver nanoparticles showing antifungal improved activity against dermatophytes VIII Jornadas de Bioquímica UTAD
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2021/10/01 - Atual Pint of Science Guarda, Portugal (2022/05/09 - 2022/05/11)
2015/04/11 - 2015/04/11 Olimpíadas de Química Júnior 2015 UTAD (2015/04/11 - 2015/04/11)
Outro
Universidade de Trás-os-Montes e Alto Douro, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2021/05/04 - 2021/05/06 1st course nanoCARE - Advanced nanomedicine
2021/02/08 - 2021/02/08 Women in Science . Presentation of the developed scientific work the a high school class of Instituto de Educación Secundaria Laxeiro, Pontevedra, Spain.
Seminário
Women in Science
Asociación Española de Investigación sobre el Cáncer, Espanha
2020/01/22 - 2020/01/24 XIII Spanish-Portuguese Conference
Congresso
Universidade de Santiago de Compostela, Espanha
2019/05/27 - 2019/05/27 Challenges and strategies in the clinical translation of cancer nanomedicines
Seminário
Instituto de Investigación Sanitaria de Santiago de Compostela, Espanha
2019/01/25 - 2019/01/25 Frontiers in Science: Translational NanoMedicine: Targeted Therapeutic Delivery for Pain, Cancer, and Inflammatory Diseases (Dr. Mansoor M. Amij, Northeastern University)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2018/10/09 - 2018/10/09 Particle engineering in the field of nasal and pulmonary administration (Prof. Rita Ambrus, University of Szeged)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2018/10/09 - 2018/10/09 Developing active molecules into medicines (Dr Sara Hudson, University of Limerick)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2018/09/14 - 2018/09/14 Inmunotherapy and nanomedicine. Translational research for autoimmune diseases (Dr Marta Vives-Pi, Universitat Autònoma de Barcelona)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2018/08/27 - 2018/08/29 12th International Conference and Workshop on Biological Barriers
Congresso
Universität des Saarlandes, Alemanha
2018/03/15 - 2018/03/15 AF2000 Multiflow FFF system for advanced characterization of proteins, biopolymers and nanoparticles (Postnova Analytics GmbH)
Oficina (workshop)
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2018/01/14 - 2018/01/16 XII Spanish-Portuguese Conference
Congresso
2017/09/15 - 2017/09/15 A pharmaceutical perspective of nanomedicine (Dr Maria José Alonso, USC)
Seminário
Centro Singular de Investigación en Química Biológica y Materiales Moleculares, Espanha
2017/04/23 - 2017/04/24 1st SPLC-CRS Young Scientist Meeting
Encontro
Universidade de Santiago de Compostela, Espanha
2017/01/10 - 2017/01/12 Entrepreneurship training on "how to generate a successful Company/spin off" and course on soft skills
Oficina (workshop)
Entrepreneurship Training and soft skills
Università degli Studi di Milano-Bicocca, Itália
2016/11/16 - 2016/11/16 Advanced experimental models and proteomics in nanomedicine and molecular medicine (Dra. Fiona McCartney, University College)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2016/06/06 - 2016/06/10 1st course of International School of Nanomedicines on “ Design and development of advanced nanomedicines to overcome biological barriers and to treat severe diseases
Oficina (workshop)
2016/05/04 - 2016/05/04 From the idea to the product: a personal perspective (Dr Jeffrey Hrkach, Moderna Therapeutics)
Seminário
Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, Espanha
2016/01 - 2016/05 7th edition YUZZ Jóvenes con ideas. Entrepreneurship program coordinated by Centro Internacional Santander Emprendimiento. Banco Santander, Santander Universidades. Entrepreneurship program: YUZZ Jóvenes con ideas.
2016/03/07 - 2016/03/09 11th International Conference and Workshop on Biological Barriers
Congresso
11th International Conference and Workshop on Biological Barriers
Universität des Saarlandes, Alemanha
2015/12/01 - 2016/01/13 Writing and design research works
Oficina (workshop)
Writing and design research works
Universidade de Santiago de Compostela, Espanha

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2021/12/30 Relatório de Estágio de Integração à Vida Profissional - Synthesis of metallic nanoparticles by green method
Arguente
Caíque Teles D'angelo (Outro)
Instituto Politécnico da Guarda, Portugal
2020 Development of multifunctional phototherapeutic nanoagents
Arguente principal
Inês Martins Dias da Mó (Mestrado)
Universidade da Beira Interior, Portugal

Membro de associação

Nome da associação Tipo de participação
2020/09/06 - Atual Controlled Release Society

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021/11/01 - Atual Ambassador of the Young Scientist Committee of the Controlled Release Society (YSC-CRS)
Outro
Distinções

Prémio

2016 YUZZ Mujer 2016 - Entrepreneurship award
Banco Santander Central Hispano SA, Espanha