Carla Oliveira (3011-EA6C-B5A3)

Curriculum Vitae

Carla Oliveira

H-INDEX = 59 (SCOPUS/ResearcherID) or 68 (GoogleScholar) PUBLICATIONS: 215 publications in the fields of Human Genetics and Molecular Oncology Accumulated Impact Factor > 1.100,00 Work cited> 15.500 times C. Oliveira is recognized internationally for her work in E-cadherin/CDH1-related diseases and hereditary cancer. She disclosed novel germline causes of Hereditary Gastrointestinal Cancer and defined somatic events in tumours with impact for patient management and therapy. Her main scientific aim is to disclose the missing heritability in Hereditary Gastric Cancer. For this, her team is exploring the whole genome, with particular emphasis in its noncoding portion. She also aims at finding biomarkers with clinical utility for earlier detection of sporadic and hereditary gastric cancer and to disclose actionable genotype-phenotype relationships in these diseases. The social and economic impact of hereditary cancer is a transversal aspect in her research and she privileges the interaction with Patients associations, such as EVITA. C. Oliveira has been a PI of projects funded with >8M Euros and team member in projects with >3M Euros total budget. She independently raised additional 4M Euros for human resources. She was invited speaker in >150 National and International conferences; is the Secretary General of the Executive Committee of European Society of Human Genetics (ESHG), member of its Scientific Program Committee and President of the Portuguese Society of Human Genetics (SPGH); National Coordinator in the European Reference Network ERN-GENTURIS on genetic tumour risk syndromes, and; head the Hereditary Diffuse Gastric Cancer branch of the SolveRD (Solving Rare diseases) EU-Project. She is a founder member of the Portuguese Group of Hereditary Tumours (PROGO) promoted by The Portuguese Society of Oncology. She is regular reviewer of National and International fellowship and grant applications. She successfully supervised 16 Masters and 17 PhD students to completion, 12 post-docs and recruited 4 junior project leaders (iFCT and CEEC individual) for her team. C. Oliveira group has also gained expertise and visibility in genomics and bioinformatics, due to active participation in international consortia and large European Projects including the coordination of the 4.6M Euros project PREVENTABLE, membership in the the European-wide research project SOLVE-RD Solve Rare diseases; the Consortium GEUVADIS and GTEx; Several COST actions, as well as the Marie Sklodowska-Curie Innovative Training Networks ITN TRAIN-EV. The group has relevant roles in management and executive functions in the GenomePT National Infrastructure for genome sequencing and the 1 Million European Genomes project. Her group actively engages in networking activities promoting collaborations with researchers and hospitals worldwide. Examples of these networks are the European Reference Network on Tumours Risk Syndromes (ERN-GENTURIS), The SolveRD consortium; The Preventable consortium; TrainEV Marie Sklodowska-Curie Action; the IGCLC - International Gastric Cancer Linkage Consortium, and the CDH1 Variant Curation Expert Panel. Her team was awarded with the Prize Alfredo da Silva on Sustainability of health systems for the work on optimized pathways of care in Hereditary cancer syndromes; more recently her team was honorable mention in the "8th Edition Prémio Rui Osório de Castro / Millennium BCP" 2024 for the project "SAPO" Paediatric sarcomas and organoids: new diagnostic biomarkers; and awarded with the Prize Maria de Sousa 2023 on "Using Genome-Wide Crispr Genetic Screens to Dissect the Molecular Mechanisms Underlying Therapy Resistance and Sensitivity in Her2-Positive Gastric Cancer", by the Fundação Bial. C. Oliveira participated in more than 50 interviews/documentaries broadcasted on TV, Radio, Internet and Newspapers over the last 20 years.

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Identificação

Identificação pessoal

Nome completo: Carla Oliveira

Nomes de citação

Oliveira, C

Identificadores de autor

Ciência ID: 3011-EA6C-B5A3
ORCID iD: 0000-0001-8340-2264
Researcher Id: F-8188-2011
Scopus Author Id: 7102223149

Telefones

Telefone

220408800 Ext.: 6173 (Profissional)

Moradas

Lab 208S4 - i3S; Rua Alfredo Allen, 208, 4200-135 Porto, Portugal, 4200-135 , Porto, Porto, Portugal (Profissional)

Websites

https://www.i3s.up.pt/research-group.php?groupid=18 (Profissional)

Domínios de atuação

Ciências Médicas e da Saúde

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Inglês	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)
Francês	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador independente (B1)
Espanhol; Castelhano	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador independente (B1)

Formação

	Grau	Classificação
2011 - 2012 Concluído	Sabbatical fellowship (BSAB/1311870456/2011) Science and Technology Foundation (FCT), PT (Outros) Fundação para a Ciência e a Tecnologia, Portugal
2005 - 2005 Concluído	Travel fellowship from European Association for Cancer Research (EACR) to Vancouver, CA (Outros) European Association For Cancer Research, Reino Unido
2004 - 2005 Concluído	Postdoc fellow (D Huntsman’s lab) (Postgraduate Certificate) Pathology Department-Laboratory Medicine, UBC, Canadá
2002 - 2005 Concluído	Post-doctoral fellowship (SFRH/BPD/9463/2002), FCT, PT (Pós-Graduação) Fundação para a Ciência e a Tecnologia, Portugal
2002 - 2004 Concluído	Postdoc fellow (R Seruca’s lab and Richard Hamelin’s lab), Ipatimup, Porto, PT & INSERM, Paris, FR (Pós-Graduação) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2000/09/01 - 2002/03/15 Concluído	Visiting Ph.D. student at Ipatimup (Doutoramento) Especialização em Human Genetics Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
1997/10/01 - 2002/03/15 Concluído	Graduate Program on Basic and Applied Biology - GABBA PhD Program (Doutoramento) Especialização em Biologia Humana Universidade do Porto Faculdade de Medicina, Portugal ""Molecular genetic profiles of sporadic and familial gastric cancer: a study of microsatellite instability and E-cadherin"" (TESE/DISSERTAÇÃO)	Aprovada
1998/08/01 - 2000/08/31 Concluído	Ph.D. student CIMR (Doctor of Philosophy) Especialização em Human Genetics University of Cambridge, Reino Unido
1997 - 1997 Concluído	FCT Trainee fellowship (PRAXIS XXI), Cancer Genetics Group - Ipatimup, Porto, PT (Outros) Fundação para a Ciência e a Tecnologia, Portugal
1995/09/01 - 1996/07/24 Concluído	Degree Training at IBILI (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Identificação de mutações no gene da beta-MHC em doentes portugueses portadores de Miocardiopatia Hipertrófica Familiar" (TESE/DISSERTAÇÃO)	19
1991/09/01 - 1995/07/31 Concluído	Biochemistry Degree (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Mutation screening of beta-myosin heavy chain gene in Portuguese kindred with Familial Hipertrofic Cardiomyopathy" (TESE/DISSERTAÇÃO)	13/20

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2015 - Atual	Investigador principal (carreira) (Investigação)	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2013/01/01 - 2015/09/30	Investigador principal (carreira) (Investigação)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Outras Carreiras

	Categoria Profissional Instituição de acolhimento	Empregador
2013 - 2023	Encarregado Geral Operacional (Assistente Operacional)	Bioinf2Bio, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2023/01/01 - Atual	Permanent Position (Tenure)	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2006/12/01 - Atual	Affiliated Professor of Oncobiology, Pathology Dpt FMUP	Universidade do Porto Faculdade de Medicina, Portugal

2005 - Atual	Consultant for cancer-associated syndromes, Ipatimup Diagnósticos	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

2011/01/01 - 2022	Permanent position (Tenure)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

2008/01/01 - 2012/12/31	Financially Independent Researcher – FCT Program Ciência 2007	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

2011/09/01 - 2012/09/01	Guest Scientist at E Izaurralde Lab, Max Planck Institute for Developmental Biology, Tuebingen, Germany (FCT - Sabbatical leave for 12 months)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
	Max Planck Institut für Entwicklungsbiologie Institut für Molekularbiologie, Alemanha
2005/07/01 - 2007/12/31	Project Leader at the Cancer Genetics Group (IDEIA Project funded by the Portuguese Innovation Agency)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

2004/04/01 - 2005/06/30	Post-doc, British Columbia Cancer Agency, Vancouver, Canada	British Columbia Cancer Agency, Vancouver, Canada, Canadá
	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2002/04/01 - 2004/03/01	Post-doc Fellow, Ipatimup (Porto, PT) & INSERM (Paris, FR) (FCT-fellowship)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

1997/10/01 - 2002/03/15	GABBA PhD student “Molecular genetic profile of sporadic and familial gastric cancer: A study of microsatellite instability and E-cadherin” supervised by Raquel Seruca and Carlos Caldas	Universidade do Porto Faculdade de Medicina, Portugal

1997/02/01 - 1997/09/30	BIC Research Student in a FCT funded Project headed by Raquel Seruca “Screening of target genes somatic mutations in microsatellite unstable carcinomas”	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

1996/08/01 - 1996/12/31	Volunteer Research Student in a project headed by Carlos Faro on “Purification, Characterization and cDNA cloning of an aspartic proteinase from Cynara Humilis”	CNC.IBILI, Portugal

1991/09/01 - 1996/07/24	Academic degree in Biochemistry with a Degree Training on “Mutation screening of beta-myosin heavy chain gene in Portuguese kindred with Familial Hipertrofic Cardiomyopathy” supervised by Carlos Faro	Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Projetos

Bolsa

	Designação	Financiadores
2021 - Atual	Hereditary Breast Ovarian Cancer - HBOC: Optimizing hereditary cancer pathways (saving costs and lives). Alfredo da Silva Award 2021 on "Sustainability of Health Systems" Sustainability of Health Systems Investigador responsável Fundação Amélia de Mello, Portugal	Fundação Amélia de Mello Em curso
2021 - Atual	CIA & EVITA Patients Association Grant for the project entitled “Hereditary Breast Ovarian Cancer – HBOC: Optimizing hereditary cancer pathways (saving costs and lives)” C&A - EVITA Investigador responsável EVITA - Associação de Apoio a Portadores de Alterações nos Genes Relacionados com Cancro Hereditário, Portugal	EVITA - Associação de Apoio a Portadores de Alterações nos Genes Relacionados com Cancro Hereditário C&A Industries LLC Em curso
2023/01/16 - 2024/07/15	DISCLOSING THE GENESIS OF HEREDITARY STOMACH CANCER THROUGH ORGAN-ON-A-CHIP TECHNOLOGY”. [DETONATE] 2022.02951.PTDC Investigador Fundação para a Ciência e a Tecnologia, I.P., Portugal	Fundação para a Ciência e a Tecnologia Em curso

Projeto

	Designação	Financiadores
2023/01/01 - 2025/12/31	"CANCER PREVENTION VS CANCER TREATMENT: THE RARE TUMOUR RISK SYNDROMES BATTLE" [PREVENTABLE] 101095483 Investigador responsável Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal	Horizon 2020 Em curso
2018/01/01 - 2024/12/31	Solving The Unsolved Rare Diseases: Hereditary Gastric Cancer-SOLVE-RD 779257 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Horizon 2020 Em curso
2021/03/31 - 2024/03/30	Life-time Risk Estimations and Genetic Modifiers Of Hereditary Diffuse Gastric Cancer - [LEGOH] PTDC/BTM-TEC/6706/2020 Investigador responsável Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2020/11 - 2022/10	COVID-19 DRIVEN NEUROLOGICAL PHENOTYPES - [NeuroCovid] NeuroCovid NeuroCovid Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	BIAL - PORTELA & C.ª, S.A Concluído
2017/10/01 - 2022/04/30	Training In Extracellular Vesicles: For Benefit In Health & Disease-Train-EV 722148 Co-Investigador Responsável (Co-IR) Bioinf2Bio, Lda, Portugal	Marie Sklodowska-Curie Innovative Training Networks Concluído
2017/06/01 - 2021/12/13	National Laboratory For Genome Sequencing And Analysis-GenomePT POCI-01-0145-FEDER-022184 22184 Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Associação para a Inovação e Desenvolvimento da FCT Programa Operacional Competitividade e Internacionalização, Programa Operacional Regional de Lisboa, Programa Operacional Regional do Algarve and by Fundação para a Ciência e a Tecnologia Concluído
2018/03/05 - 2021/09/04	Long Survival In Patients With High-Grade Serous Carcinoma Of The Ovary: A Molecular And Clinical Study-OVARIO OVARIO Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Instituto Portugues de Oncologia de Lisboa Francisco Gentil EPE Concluído
2018/07/01 - 2021/06/30	Solving The 3D Chromatin Structure Of CDH1 Locus To Identify Disease-Associated Mechanisms - 3DCHROME POCI-01-0145-FEDER-30164 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluído
2017/01/01 - 2020/12/31	WP3 - Principal Investigator - Csc Plasticity: Emt And Stem Cell State Generation From "Tackling Cancer Stem Cells: A Challenge And An Opportunity To Advance In Anti-Cancer Therapy-CANCERSTEM POCI-01-0145-FEDER-016390 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Associação para a Inovação e Desenvolvimento da FCT Concluído
2016/02/01 - 2020/06/30	The Role Of Gastric Cancer Cell-Derived Extracellular Vesicles GCEVs Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Ipatimup Board of Directors Concluído
2016/05/01 - 2020/04/30	Diabetes & Obesity At The Crossroads Between Oncological And Cardiovascular Diseases – A System Analysis Nettwork Towards Precision Medicine-DOCnet NORTE-01-0145-FEDER-000003 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Programa Operacional Regional do Norte Concluído
2016/05/01 - 2019/12/31	WP1 - Principal Investigator - Mapping Genetic And Phenotypic Heterogeneity In Her2 Positive Cancers To Anticipate And Counteract Resistance Phenotypes NORTE-01-0145-FEDER-000029 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Programa Operacional Regional do Norte Concluído
2016/06/01 - 2019/12/01	A 3D microarray platform for the high-throughput analysis of the role of the extracellular matrix in cancer-associated epithelial-to-mesenchymal transitions Provided by PTCRIS: 141144 PTDC/BBB-ECT/2518/2014 Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/02/01 - 2019/09/30	The Intronic Regulation of the CDH1 Gene IntCDH1 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Ipatimup Board of Directors Concluído
2014/01/01 - 2016/12/31	Defining The Contribution Of Mutations In CDH1 Non-Coding Regions And Other Known Susceptibility Genes To Hereditary Gastric Cancer NSFC_2014 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	American association “NSFC - No Stomach for Cancer” Concluído
2013/09/01 - 2016/11/30	Using NGS To Uncover Structural And Regulatory Variation In Gastric Cancer NGSGC_2013 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Coimbra Genomics and BGI Concluído
2012/03/01 - 2015/10/31	Adhesion, Differentiation and Invasion: different processes, common cadherin players 120049 Provided by PTCRIS: 120049 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2012/05/01 - 2015/08/31	TUMORTAG - Tumor-targeted nanoparticles for early diagnosis of gastric cancer 120958 Provided by PTCRIS: 120958 Co-Investigador Responsável (Co-IR) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/04/01 - 2014/09/30	New E-cadherin RNAs: the dark side of a tumour suppressor gene 110785 Provided by PTCRIS: 110785 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/04/01 - 2014/09/30	Tumour spectrum in Hereditary Diffuse Gastric Cancer 110294 Provided by PTCRIS: 110294 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010/05 - 2013/10	Functional genomics of ribosome infidelity phenotypes associated to human diseases. 98850 Provided by PTCRIS: 98850 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2009/01/30 - 2012/07/29	Exploring the role of E-Cadherin-HER interaction in the search of molecular biomarkers for the clinical management of gastric cancer patients Provided by PTCRIS: 82923 82923 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2008/07/01 - 2011/12/31	MLK3, a new mutated gene in MSI colorectal cancer 68310 Provided by PTCRIS: 68310 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2009/01 - 2011/12	Implementation of a Nacional Facility for DNA Microarrays: Phase II 64745 Provided by PTCRIS: 64745 Investigador Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007/08 - 2010/11	Papel de novos mecanismos regulatórios na perda de expressão da caderina-E 72168 Provided by PTCRIS: 72168 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2005/07/01 - 2008/07/01	In mismatch repair deficiency colorectal cancer are BRAF and KRAS new prognostic and therapeutic tools? 56921 Provided by PTCRIS: 56921 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2005/07/01 - 2008/07/01	Identification of molecular mechanisms underlying gastric cancer in families positive and negative for E-cadherin germline mutations 58111 Provided by PTCRIS: 58111 Investigador responsável Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2005/07 - 2008/06	Identification of signaling pathways involved in Cdx2 regulation in two human models of altered intestinal differentiation: intestinal metaplasia and juvenile polyposis. 55840 Provided by PTCRIS: 55840 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em revista

Celina São José; José Garcia-Pelaez; Marta Ferreira; Oscar Arrieta; Ana André; Nelson Martins; Samantha Solís; et al. "Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer". Gastric Cancer (2023): http://dx.doi.org/10.1007/s10120-023-01395-0.
10.1007/s10120-023-01395-0
Catarina Guedes Vaz; Jéssica Rodrigues; Diogo Pereira; Ilda Matos; Carla Oliveira; Maria José Bento; Rui Magalhães; Manuel Correia; Luis Maia. "The crosstalk between Stroke and Cancer: Incidence of cancer after a first-ever cerebrovascular event in a population-based study". European Stroke Journal (2023): http://dx.doi.org/10.1177/23969873231181628.
10.1177/23969873231181628
Joana Guerra; Carla Pinto; Pedro Pinto; Manuela Pinheiro; Catarina Santos; Ana Peixoto; Carla Escudeiro; et al. "Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer". Cancers (2023): https://www.mdpi.com/2072-6694/15/17/4313.
10.3390/cancers15174313
Xi Luo; Jamie L Maciaszek; Bryony A Thompson; Huei San Leong; Katherine Dixon; Sónia Sousa; Michael Anderson; et al. "Optimising clinical care throughCDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines". Journal of Medical Genetics (2023): http://dx.doi.org/10.1136/jmg-2022-108807.
10.1136/jmg-2022-108807
Maqueda, Joaquín J.; Giovanazzi, Alberta; Rocha, Ana Mafalda; Rocha, Sara; Silva, Isabel; Saraiva, Nadine; Bonito, Nuno; et al. "Adapter dimer contamination in sRNA-sequencing datasets predicts sequencing failure and batch effects and hampers extracellular vesicle-sRNA analysis". Journal of Extracellular Biology 2 6 (2023): http://dx.doi.org/10.1002/jex2.91.
10.1002/jex2.91
Celina São José; Carla Pereira; Marta Ferreira; Ana André; Hugo Osório; Irene Gullo; Fátima Carneiro; Carla Oliveira. "3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer". Biology (2023): https://doi.org/10.3390/biology12060803.
10.3390/biology12060803
Joaquín J. Maqueda; Mafalda Santos; Marta Ferreira; Sérgio Marinho; Sara Rocha; Mafalda Rocha; Nadine Saraiva; et al. "NGS Data Repurposing Allows Detection of tRNA Fragments as Gastric Cancer Biomarkers in Patient-Derived Extracellular Vesicles". International Journal of Molecular Sciences 24 10 (2023): 8961. https://doi.org/10.3390/ijms24108961.
Publicado • 10.3390/ijms24108961
Yaldiz, Burcu; Kucuk, Erdi; Hampstead, Juliet; Hofste, Tom; Pfundt, Rolph; Corominas Galbany, Jordi; Rinne, Tuula; et al. "Twist exome capture allows for lower average sequence coverage in clinical exome sequencing". Human Genomics 17 1 (2023): http://dx.doi.org/10.1186/s40246-023-00485-5.
10.1186/s40246-023-00485-5
Denommé-Pichon, Anne-Sophie; Matalonga, Leslie; de Boer, Elke; Jackson, Adam; Benetti, Elisa; Banka, Siddharth; Bruel, Ange-Line; et al. "A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing". Genetics in Medicine 25 4 (2023): 100018. http://dx.doi.org/10.1016/j.gim.2023.100018.
10.1016/j.gim.2023.100018
Francesca Forzano; Olga Antonova; Angus Clarke; Guido de Wert; Sabine Hentze; Yalda Jamshidi; Yves Moreau; et al. "Correction to: Reply to Letter by Tellier et al., ‘Scientific refutation of ESHG statement on embryo selection’". European Journal of Human Genetics (2023): http://dx.doi.org/10.1038/s41431-022-01263-y.
10.1038/s41431-022-01263-y
Francesca Forzano; Olga Antonova; Angus Clarke; Guido de Wert; Sabine Hentze; Yalda Jamshidi; Yves Moreau; et al. "Reply to Letter by Tellier et al., ‘Scientific refutation of ESHG statement on embryo selection’". European Journal of Human Genetics (2023): http://dx.doi.org/10.1038/s41431-022-01241-4.
10.1038/s41431-022-01241-4
Garcia-Pelaez, José; Barbosa-Matos, Rita; Lobo, Silvana; Dias, Alexandre; Garrido, Luzia; Castedo, Sérgio; Sousa, Sónia; et al. "Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes". The Lancet Oncology 24 1 (2023): 91-106. http://dx.doi.org/10.1016/s1470-2045(22)00643-x.
Acesso aberto • 10.1016/s1470-2045(22)00643-x
Daniel A. Ferreira; João P. Conde; Mario Rothbauer; Peter Ertl; Pedro L. Granja; Carla Oliveira. "Bioinspired human stomach-on-a-chip with in vivo like function and architecture". Lab on a Chip (2023): https://doi.org/10.1039/D2LC01132H.
10.1039/D2LC01132H
Linda Hendricks; Nicoline Hoogerbrugge; Hanka Venselaar; Stefan Aretz; Isabel Spier; Eric Legius; Hilde Brems; et al. "Genotype-phenotype associations in a large PTEN Hamartoma Tumor Syndrome (PHTS) patient cohort". European Journal of Medical Genetics (2022): http://dx.doi.org/10.1016/j.ejmg.2022.104632.
10.1016/j.ejmg.2022.104632
Jihenne BEN AISSA-HAJ; Hugo Pinheiro; François Cornelis; Molka Sebai; Didier Meseure; Adrien Briaux; Philippe Berteaux; et al. "The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility". Genes (2022): https://www.mdpi.com/2073-4425/13/12/2213.
10.3390/genes13122213
Francesca Forzano; Olga Antonova; Angus Clarke; Guido de Wert; Sabine Hentze; Yalda Jamshidi; Yves Moreau; et al. "Correction: The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice". European Journal of Human Genetics (2022): http://dx.doi.org/10.1038/s41431-022-01155-1.
10.1038/s41431-022-01155-1
Coudert, Marie; Drouet, Youenn; Delhomelle, Hélène; Svrcek, Magali; Benusiglio, Patrick R; Coulet, Florence; Clark, Dana Farengo; et al. "First estimates of diffuse gastric cancer risks for carriers ofCTNNA1germline pathogenic variants". Journal of Medical Genetics 59 12 (2022): 1189-1195. http://dx.doi.org/10.1136/jmg-2022-108740.
10.1136/jmg-2022-108740
Mafalda Santos; Marta Ferreira; Patrícia Oliveira; Nuno Mendes; Ana André; André F. Vieira; Joana B. Nunes; et al. "Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth". Biology (2022): https://www.mdpi.com/2079-7737/11/7/1046.
10.3390/biology11071046
Santos, Mafalda; Fidalgo, Ana; Varanda, Ana Sofia; Soares, Ana Raquel; Almeida, Gabriela M.; Martins, Diana; Mendes, Nuno; Oliveira, Carla; Santos, Manuel A. S.. "Upregulation of tRNA-Ser-AGA-2-1 Promotes Malignant Behavior in Normal Bronchial Cells". Frontiers in Molecular Biosciences 9 (2022): http://dx.doi.org/10.3389/fmolb.2022.809985.
10.3389/fmolb.2022.809985
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Velho, S.; Moutinho, C.; Cirnes, L.; Albuquerque, C.; Hamelin, R.; Schmitt, F.; Carneiro, F.; Oliveira, C.; Seruca, R.. "BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis?". BMC Cancer 8 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-53149097362&partnerID=MN8TOARS.
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Oliveira, C.; De Bruin, J.; Nabais, S.; Ligtenberg, M.; Moutinho, C.; Nagengast, F.M.; Seruca, R.; Van Krieken, H.; Carneiro, F.. "Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour". Oncogene 23 12 (2004): 2236-2240. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842591223&partnerID=MN8TOARS.
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10.1016/S0002-9440(10)65665-9

Capítulo de livro

Irene Gullo; José Garcia-Pelaez; Rui Morais; Yuchun Ding; Carla Oliveira; Fátima Carneiro. "Histopathology of Hereditary Diffuse Gastric Cancer: From Grossing and 3D Microscopy to Immunophenotypic and Molecular Profiling". 2023.
10.1007/978-3-031-21317-5_9
Gianluca Tedaldi; Celina São José; Carla Oliveira. "Other Syndromes and Genes Associated with Gastric Cancer Predisposition". 2023.
10.1007/978-3-031-21317-5_7
Silvana Lobo; Paulo S. Pereira; Patrick R. Benusiglio; Carla Oliveira. "CTNNA1, a New HDGC Gene: Inactivating Mechanisms and Driven Phenotypes". 2023.
10.1007/978-3-031-21317-5_5
Gullo, Irene; Oliveira, Carla; van der Post, Rachel S.; van Dieren, Jolanda M.; Davis, Jeremy L.; Bougen-Zhukov, Nicola; Guilford, Parry; Carneiro, Fátima. "Updated perspective and directions on hereditary diffuse gastric cancer". In Research and Clinical Applications of Targeting Gastric Neoplasms, 217-258. Elsevier, 2021.
10.1016/b978-0-323-85563-1.00011-3
Carneiro, F; Guilford, P.; Oliveira C; van der Post RS. "Genetic tumour syndromes of the digestive system-Hereditary diffuse gastric cancer". In Molecular Pathology of Neoplastic Gastrointestinal Diseases, 535-538. WHO Classification of Tumours, 2019.
Publicado
Oliveira, C.; Pinheiro, H.; Figueiredo, J.; Seruca, R.; Carneiro, F.; Oliveira, Carla; Pinheiro, Hugo; et al. "E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer". In Prog Mol Biol Transl Sci, 337-359. Elsevier, 2013.
Aceite para publicação • 10.1016/B978-0-12-394311-8.00015-7
Leite, M.; Corso, G.; Sousa, S.; Carvalho, J.; Roviello, F.; Oliveira, C.; Figueiredo, C.; Seruca, R.. "Non- CDH1 -associated familial gastric cancer and epigenetics factors". In International Journal of Cancer. 2013.
10.1007/978-94-007-6570-2_10
Carvalho, J.; Pinheiro, H.; Oliveira, C.. "E-Cadherin germline mutations". In Molecular Pathology of Neoplastic Gastrointestinal Diseases. 2013.
10.1007/978-94-007-6570-2_5
Carvalho, J.; Pinheiro, H.; Oliveira, C.. "Alternative mechanisms to germline CDH1 mutations in hereditary diffuse gastric cancer". In Molecular Pathology of Neoplastic Gastrointestinal Diseases. 2013.
10.1016/j.febslet.2012.07.045
Carneiro, F; Oliveira C; Seruca, R. "Hereditary Diffuse Gastric Cancer and Other Gastric Cancers Associated with Hereditary Predisposition Syndromes". In Molecular Pathology of Neoplastic Gastrointestinal Diseases, 83-107. Estados Unidos: Springer, 2013.
Publicado
VELHO, SERGIA; Oliveira C; Raquel Seruca. "PIK3CA Gene Alterations in Human Cancers". In In Bioinformatics in Cancer and Cancer Therapy. Springer. Series: Cancer Drug Discovery and Development, 2009.
Publicado
Karam, R.; Oliveira C; Seruca, R; Carneiro, F. "Câncer Gástrico Hereditário". In Atualização em Câncer Gástrico. Portugal: Tecmedd, 2005.
Publicado

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2024/01/08	"Tumours supressor genes and genetic instability"	Lecture on PDMOM/MOM PhD program – Oncobiology course – IPATIMUP (Porto, Portugal)
2023/12/11	"Discovery of disease mechanisms: Impact for patients, their families and the society"	Lecture Molecular Mechanisms of Disease\| PhD Program in Health Sciences \| Faculty of Medicine of the University of Coimbra (Coimbra, Portugal)
2023/11/22	"CTNNA1 germline variants: Genotype-phenotype associations"	European Reference Network GENTURIS Webinar (Online)
2023/11/01	"Genotype-phenotype associations and life-time risks in Hereditary Diffuse Gastric Cancer and Lobular Breast Cancer syndrome"	NIH seminar Series (Washington DC, Estados Unidos)
2023/10/21	"Risco de cancro à nascença: informação, testes genéticos e profilaxia"	Conferência: Risco de Doença: Nascer com a espada sobre a cabeça”.FOLIO 2023, CASA JOSÉ SARAMAGO – BIBLIOTECA MUNICIPAL (Óbidos, Portugal)
2023/10/13	"CDH1 VARIANTS AND PHENOTYPES"	CDH1 related hereditary diffuse type gastric cancer: from preventive total gastrectomy to optimal endoscopic surveillance. European Joint Program for Rare Diseases (Nijmegen, Países Baixos)
2023/10/12	"Functional genomics: Tools and models to solve rare disease causes"	GROUP LEADER SEMINAR SERIES. i3S CANCER RESEARCH LINE (Porto, Portugal)
2023/09/29	"Hereditary Gastric Cancer"	ESMO PRECEPTORSHIP PROGRAMME on hereditary cancer genetics - Multidisciplinary management, standards of care and future perspectives. (Paris, França)
2023/09/23	"Variant Classification"	Parallel Specialized lectures. 4th Course in Hereditary Cancer Genetics (Bertinoro, Itália)
2023/09/22	"Hereditary Gastric Cancer"	Tumours Syndromes session. 4th Course in Hereditary Cancer Genetics (Bertinoro, Itália)
2023/09/21	"Basics in Exome analysis"	Parallel Specialized lectures. 4th Course in Hereditary Cancer Genetics (Bertinoro, Itália)
2023/04	"Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increases penetrance of Hereditary Diffuse Gastric Cancer"	Solve-RD Final Meeting (Prague, República Checa)
2023/03/04	"DAS GUIDELINES À PRÁTICA CLÍNICA DO DIA A DIA"	Meeting One year Together: A new era for BRCAm Ovarian and Breast cancer patients. (Porto, Portugal)
2023/02/14	"Cancro Hereditário do estômago: Aspetos clínicos e moleculares"	Lesson to high School students ESCOLA RODRIGUES DE FREITAS (Porto, Portugal)
2023/01/05	"Hereditary Gastric Cancer: Clinical and molecular aspects"	Lesson Unidade Curricular: ONCOBIOLOGIA I & II. Programa de Doutoramento em Medicina e Oncologia Molecular; Programa de Doutoramento em Biomedicina; Programa de Doutoramento em Patologia e Genética Molecular (Porto, Portugal)
2022/11/30	"Dos genes aos genomas: o caminho para a descoberta de novas causas de doenças"	Panel Translational Research. Fórum Medicina de Precisão em Oncologia. (Porto, Portugal)
2022/11/17	"Estratégia Nacional para a Medicina Genómica: antecedentes, conceito e iniciativas em curso"	Mesa de Medicina Genómica. 19º Congresso Nacional Oncologia. (Porto, Portugal)
2022/10/20	"Hereditary Gastric Cancer – updates"	Hereditary predisposition to cancer Session. II INTERNACIONAL EINSTEIN SIMPOSIUM ON PRECISION MEDICINE (Online, Brasil)
2022/10/19	"Hereditary Gastric Cancer: Clinical and molecular aspects"	Patient Involvement and Ethics – Summer School in Translational Cancer Research 2022. Cancer care Europe. (Albufeira, Portugal)
2022/10/03	"Phenotypes and multiomics: a likely solution to solve the unsolved in rare diseases"	Computational Biology and Bioinformatics series. Institute of Molecular Medicine (Lisbon, Portugal)
2022/10	"Genomic data and clinical information: the two pillars that sustain genetic diagnosis I & II"	Graduation in genetics and genomics in clinics (GGGC). NOVA Medical School\| Faculdade de Ciências Médicas Universidade NOVA de Lisboa (Lisbon, Portugal)
2022/09	"Genotype-Phenotype Correlations in CDH1 and CTNNA1 variant carriers: a tool to understand variant actionability and improve clinical guidelines"	2nd MILAN CANCER MEETING Innovations in prevention, research and care (Milan, Itália)
2022/09	"Cancer Epigenetics"	11th WORKSHOP ON CANCER RESEARCH: Biological and Molecular basis (Porto, Portugal)
2022/09	"Hereditary diffuse gastric cancer: Status Quo"	CBGM 2022 - 33rd Brazilian Congress of Medical Genetics (Curitiba, Brasil)
2022/06	"CDH1 LOCUS DISRUPTION: genome-wide functional impacts"	Session 5: Biomedical Genetics. II International Meeting of the Portuguese Society of Genetics (Évora, Portugal)
2022/05	"Cancer Prevention and Early Detection"	Encontro Ciência 2022 – Fighting Cancer Portuguese and European Initiatives (Lisbon, Portugal)
2022/03	"Genotype-Phenotype Associations in CDH1 pathogenic and likely pathogenic variant carrier families"	Scientific session: CDH1 & Gastric Cancer Genetics – online. (Online)
2022/02	"The CDH1 and other familial gastric cancer genotype-phenotype associations: an ERN GENTURIS project"	ERN GENTURIS Tumour Predisposition Conference – online. (Online)
2022/02	"TIPS to Get Your Research Project Funded"	LYRIS Course - Online Event. (Online)
2021/12	"Síndromes ligados ao cancro: o contexto ideal para prevenção"	Breast Center Seminar in CHUSJ (Porto, Portugal)
2021/11	"The Genetics Scientist perspective" - Ethical imperative - the importance of quality on diagnostics and practice in Genetic Medicine.	25th Annual Meeting SPGH (Online)
2021/10	"Novos Genes Novas Recomendações" - Thematic Session "New Genes New Recommendations"	XI National Congress of Senology (Porto, Portugal)
2021/10	"CTNNA1 database"	ERN GENTURIS meeting – online.
2021/10	"Gastric cancer: predisposing factors and clinical biomarkers"	III Symposium on Applied Biochemistry in University of Minho. Braga
2021/09	"Cancer Epigenetics"	10th Workshop on Cancer Research: Biological and Molecular basis, i3S (Porto, Portugal)
2021/04	"Genotypes vs Phenotypes: Solving the unsolved in Hereditary Diffuse Gastric Cancer"	Group Leader Seminar at i3S (Porto, Portugal)
2021/02	"Síndromes associados a cancro: o ponto de encontro da investigação em genética humana e da vida real".	Questions & Answers (Q & A) 2nd Edition. Portuguese Society of Genetics. (Porto, Portugal)
2021/01	"WP5: Bioinformatics tools to explore cell/EVs contents"	TRAIN-EV Virtual Meeting (Online)
2020/05	"Familial Gastric Cancer: hidden layers of a genetically heterogeneous Disease"	CI-IPOP/EPOP Scientific meeting - Online CI-IPOP/EPOP (Porto, Portugal)
2019/12	"Hereditary Diffuse Gastric Cancer: From genes to disease phenotypes"	2019 Seoul International Gastric Cancer Forum International Gastric Cancer Forum (Seoul, Coreia do Sul)
2019/07	"Molecular determinants of gastric cancer: predisposing factors and intra-tumoral heterogeneity"	3rd Annual Meeting CINBIO Centro De Investigaciones Biomédicas (Vigo, Espanha)
2019/06	"European Reference Networks: What is in it for me?".	European Human Genetics Conference 2019 European Human Genetics (ESHG) (Gothenburg, Suécia)
2019/06	"Beyond the coding sequence of CDH1: lessons from Hereditary Diffuse Gastric Cancer syndrome".	CEDOC Seminar CHRONIC DISEASES RESEARCH CENTER (Lisboa, Portugal)
2019/06	"Beyond the coding sequence of CDH1: lessons from Hereditary Diffuse Gastric Cancer syndrome".	CEDOC Seminar CHRONIC DISEASES RESEARCH CENTER (Lisboa, Portugal)
2019/03	"CDH1 locus inactivation: phenotypes and novel mechanisms".	2019 IGCLC Hereditary Diffuse Gastric Cancer Consensus Clinical Guidelines Meeting IGCLC (Wanaka, Nova Zelândia)
2019/01	"Regulation of the CDH1 locus: Intronic sequences command CDH1 expression"	VIII Portuguese Meeting: ptRNA 2019 i3S - Instituto de Investigação e Inovação em Saúde (Porto, Portugal)
2018/12	"Gastric Cancer: novel germline predisposing factors and somatic prognostic markers"	Integrative Program Seminar Series: Cancer Research Line (Porto, Portugal)
2018/11	"Panel Discussion: What are ERNs and what is in there for me?"	Satellite Meeting-European Reference Networks in Portugal on the 22nd Annual Meeting SPGH (Porto, Portugal)
2018/09	"Up-date in Hereditary Gastric Cancer"	Session: GENETIC FOR LIFE. The new Frontiers in gastric cancer diagnosis and treatment. (Forli, Itália)
2018/07	"Gastric Cancer: the genetics behind the biology of a lethal disease"	Encontro com a Ciência e a Tecnologia em Portugal. Tema - 3 - Saúde de Qualidade – ONCOLOGIA. (Lisbon, Portugal)
2018/05	"Round Table: A PhD for the XXI century"	1st i3S PhDay (Porto, Portugal)
2018/05	"Tumor cell invasion and metastasis: Epithelial to mesenchymal transition and cancer cell plasticity"	Lecture on VII Workshop on Cancer Research (Porto, Portugal)
2018/05	"Presentation of the European Reference Network GENTURIS - Genetic tumour risk syndromes: opportunities to improve health care for patients with hereditary cancer syndromes in Europe"	Workshop on 3rd ASPIC International Congress (Lisboa, Portugal)
2018/05	"GEIVEX / Portuguese branch"	ISEV2018 Annual Meeting - Meet the National Societies and Outreach Strategies (Barcelona, Espanha)
2018/04	"Hereditary Diffuse Gastric Cancer"	Lecture on 2nd Spring Course in Hereditary Cancer Genetics. (Bertinoro, Itália)
2018/03	"Redefining Germline Mechanisms of Disease"	Lecture on GABBA Oncobiology Module (Porto, Portugal)
2018/02	"Horizontally transferable mechanisms in gastric cancer: modulators of cellular behavior and cancer biomarkers".	1st Meeting on Vesicular Biology (Coimbra, Portugal)
2018/01	"Genes supressores tumorais e instabilidade genética"	Lecture on PDMOM/MOM PhD program – Oncobiology course – IPATIMUP (Porto, Portugal)
2017/12	"From diseases to causative molecular events: genetic, epigenetic and horizontally transferable mechanisms"	Lecture on Molecular Mechanisms of Disease, PhD Program in Health Sciences, FMUC FMUC (Coimbra, Portugal)
2017/11	Light and Antibodies Fighting Gastric Cancer	I3S Distinguished Lectures. I3S Annual Meeting 2017 i3S (Póvoa de Varzim, Portugal)
2017/10	"Genetics and gastric cancer"	Session: Which diseases are inherited? UEG United European Gastroenterology Week 2017 UEG (Barcelona, Espanha)
2017/07	"Hereditary Gastric Cancer"	Lecture on post-graduate course - A Multidisciplinary approach to Hereditary GI Cancers: from Bench to Bedside (ESDO-ESGE-InSIGHT) ESDO-ESGE-InSIGHT (Florence, Itália)
2017/06	"CDH1 germline noncoding defects: the missing mechanisms in Hereditary Diffuse Gastric Cancer"	One Day Symposium with Patrick Tan: Knowns & Unknowns in Gastric Cancer and Other Tumours of the Digestive System i3S (Porto, Portugal)
2017/05	"Clinical utility of high-throughput genome analysis and impact for patient treatment"	First DOCnet Consortium Meeting, Faculty of Medicine of the University of Porto (FMUP) FMUP (Porto, Portugal)
2017/05	"microRNAs in screening programs of high risk patients/regions: how far are we?"	Esophagus and Gastric Cancer Session. Leaping Forward Oncology – International Clinical Congress 2017 International Clinical Congress (Lisbon, Portugal)
2017/05	"microRNAs in screening programs of high risk patients/regions: how far are we?"	Esophagus and Gastric Cancer Session. Leaping Forward Oncology – International Clinical Congress 2017 Leaping Forward Oncology (Lisbon, Portugal)
2017/05	"Tumor cell invasion and metastasis: Epithelial to mesenchymal transition and cancer cell plasticity"	VII Workshop on Cancer Research IPATIMUP (Porto, Portugal)
2017/05	"Current challenges in familial gastric cancer"	Lecture on Master course - Oncobiologia da Faculdade de Medicina de Lisboa (FMUL) – Módulo de Risco Familiar FMUL (Lisbon, Portugal)
2017/05	"Oncogenes and Tumor suppressor genes"	Invited lecture at ICBAS ICBAS (Porto, Portugal)
2017/04	"The translational value of germline and somatic mechanisms for diagnosis and anti-cancer therapy in gastric cancer"	Integrative Program Seminar Series: Cancer Research Line i3S (Porto, Portugal)
2017/03	"Molecular determinants of gastric cancer: genotypes, phenotypes and impact in progression and treatment"	Seminar at Instituto de Saúde Pública da Universidade do Porto (ISPUP) ISPUP (Porto, Portugal)
2017/02	"Redefining germline mechanisms of disease"	Lecture on GABBA Oncobiology Module GABBA (Porto, Portugal)
2017/01	"Genes supressores tumorais e instabilidade genética"	Lecture on PDMOM/MOM PhD program – Oncobiology course IPATIMUP (Porto, Portugal)
2016/12	"From disease to causative gene events: an omics approach in gastric cancer"	Keynote Lecture XIX National Congress of Biochemistry SPB (Guimarães, Portugal)
2016/10	"Current challenges in familial gastric cancer"	Symposium update – erbliche gastrointestinale karzinomerkrankungen Munich (Munich, Alemanha)
2016/08	"Molecular determinants of gastric cancer: genotypes, phenotypes and impact in progression and treatment"	Seminar series National Cancer Center Research Institute National Cancer Center Research Institute (Tokyo, Japão)
2016/07	"Cancro gástrico esporádico e familiar: aspectos genéticos"	Congresso da EUROPACOLON Portugal em Oncologia Digestiva Fundação Cupertino Miranda (Porto, Portugal)
2016/06	"From single genes to full genomes, from single mechanisms to complex pathways"	iBiMED International Advanced Training School. Omics in Biomedicine: linking genes and metabolites iBiMED (Aveiro, Portugal)
2016/05	"Tumor cell invasion and metastasis: Epithelial to mesenchymal transition and cancer cell plasticity"	VI Workshop on Cancer Research IPATIMUP (Porto, Portugal)
2016/04	"Epigenetic mechanisms of gene expression regulation in gastric cancer"	ICVS Course Epigenetics - from mechanisms to disease ICVS (Braga, Portugal)
2016/04	"From single causing genetic mutations to multiple modifying mutations in cancer- the journey of a life-time"	III Jornadas da Bioquímica "Bioquímicos pelo Mundo” (Porto, Portugal)
2016/04	"Hereditary Diffuse Gastric Cancer"	1st Spring Course in Hereditary Cancer Genetics (Bertinoro, Itália)
2016/03	"Effect of cancer cell-derived extracellular vesicles over normal cells from the microenvironment"	Spring Meeting of the Cost Action European Network on Microvesicles and Exosomes in Health and Disease (Ioannina, Grécia)
2015/10	"Molecular determinants of cancer: genotypes and phenotypes"	iBiMED Seminar Series iBiMED (Aveiro, Portugal)
2015/07	"From single causing genetic mutations to multiple modifying mutations in cancer"	INEB Summer Science Club: Integrating Competences INEB (Porto, Portugal)
2015/06	"GASTRIC CANCER THERAPY, THE ERA OF FUNCTIONAL GENOMICS"	Post-graduated course “Cancer therapy: from basic research to clinic“ University of Minho (Braga, Portugal)
2015/05	"Genomics and Transcriptomics in cancer research"	V Workshop on Cancer Research – Biological and molecular basis IPATIMUP/ICBAS (Porto, Portugal)
2015/04	"Genómica e Bioinformática: O que o clínico deve saber"	XXXVI Congresso Português de Cardiologia (Albufeira, Portugal)
2015/02	"The genomics and bioinformatics era: does it help understanding better sporadic and hereditary cancer?"	Research Seminar, IPO Instituto Português de Oncologia - Lisboa (Lisbon, Portugal)
2015/01	"Using NGS to uncover structural and regulatory variation in gastric cancer"	COIMBRA GENOMICS Annual MEETING, CURIA (Coimbra, Portugal)
2014/11	"Germline and somatic determinants of gastric cancer: Next Generation Sequencing and Functional Genomics"	Ministry of Health - MD Anderson Cancer Center Joint Conference on Gastric and Hereditary Cancer Lisbon Academic Medical Center (Lisbon, Portugal)
2014/11	"Through the looking glass: the reversion of EMT"	1st International Congress ASPIC – Associação Portuguesa de Investigação em Cancro ASPIC (Lisbon, Portugal)
2014/10	"Hereditary GI cancer: New genes, old diseases"	UEG – United European Gastroenterology Week UEG (Vienna, Áustria)
2014/10	"The role and cargo of EVs in epithelial-mesenchymal-epithelial transitions and gastric cancer progression"	II GEIVEX SYMPOSIUM: Extracellular vesicles, from the bench to the clinics. Satellite Meeting of the Portuguese Groups on Extracellular Vesicles GEIVEX (Taragona, Espanha)
2014/10	"The role and cargo of EVs in epithelial-mesenchymal-epithelial transitions and gastric cancer progression"	Autumn Meeting of the Cost action European Network on Microvesicles and Exosomes in Health and Disease (Palermo, Itália)
2014/07	"Can you use next generation sequencing data from tumours to rationally select targeted therapy approaches?"	BioP5med Unworkshop, IGC - Oeiras IGC (Lisbon, Portugal)
2014/05	"Metastable phenotypes"	ONCOBIOLOGY - genes and tumoral microenvironment Seminar Series Medical Sciences Faculty - NOVA University (Lisbon, Portugal)
2014/05	"Genomics and Transcriptomics in cancer research"	IV Workshop on Cancer Research IPATIMUP (Porto, Portugal)
2014/04	"Next Generation Sequencing (NGS): Principles and clinical applications"	6th Scientific Meeting of the Portuguese Society of Clinical Chemistry and Laboratorial Medicine Portuguese Society of Clinical Chemistry and Laboratorial Medicine (Coimbra, Portugal)
2014/03	"Germline and somatic determinants in gastric cancer: a focus on E-cadherin"	Oncology Meetings: Gastric Cancer - State of Art University of Minho (Braga, Portugal)
2013/12	"Using NGS and in Vitro Models to Understand Structural and Regulatory Variation in Gastric Cancer"	Bio-IT World and Cambridge Healthtech Institute’s Second Annual, Clinical Genomics and Genome Informatics Europe, Deciphering Disease through Sequencing Data Bio-IT World and Cambridge Healthtech Institute (Lisbon, Portugal)
2013/11	"Using molecular stratification and NGS to Understand Structural and Regulatory Variation in Gastric Cancer"	17th SPGH Annual Meeting SPGH (Coimbra, Portugal)
2013/11	"Modulation of cell-cell adhesion in cancer and epithelial-mesenchymal-epithelial transition?"	IMM Monday lectures IMM (Lisbon, Portugal)
2013/10	"Metastatic pathways in gastric cancer: is there a role of Extracellular Vesicles?"	2nd Meeting COST Action_BM1202 ME-HAD Semmelweis University (Budapest, Hungria)
2013/10	"Germline and somatic determinants in gastric cancer - impact in diagnosis, prognosis and treatment"	Monday Seminar Medical Faculty University of Porto FMUP (Porto, Portugal)
2013/10	"Modulation of E-cadherin expression and function in gastric cancer - clinical and molecular features"	19TH GI CANCER FORUM - The Martin Cohen Lecture Theatre, CRUK CRI - Li Ka Shing Centre (Cambridge, Reino Unido)
2013/07	"Molecular mechanisms modulating the function of the invasion suppressor protein E-cadherin"	Institut Curie, Université Paris-SUD (Paris, França)
2013/06	"HDGC: Updated guidelines for clinical management"	IGCC 2013, 10th International Gastric Cancer Congress IGCC (Verona, Itália)
2013/05	"Cancer Metastization: Examples from the wet lab"	III Workshop on Cancer Research IPATIMUP (Porto, Portugal)
2013/05	"Genetics of hereditary diffuse gastric cancer - HDGC"	Funderburg Symposium - “Current Approach to Hereditary Diffuse Gastric Cancer (HDGC) syndrome”. DDW 2013 Digestive Disease Week Orlando DDW (Orlando, Estados Unidos)
2013/01	"From disease to mechanisms: old and new stories about E-cadherin"	Instituto Mexicano de Seguro Social Guadalajara Mexico IMMS (Guadalajara, México)
2013/01	"Dissecting the role of cadherins with OMICS technologies"	Course: “New frontiers of OMICs in Medicine - from the lab to a clinical setting” IBILI (Coimbra, Portugal)
2012/09	"Dissecting the role of cadherins with genome-wide technologies"	User Meeting Genómica IBILI (Coimbra, Portugal)
2012/06	"Novel molecular mechanisms modulating the function of the invasion suppressor protein E-cadherin"	2nd IBEC-INEB Advanced Summer School IBEC Barcelona (Barcelona, Espanha)
2012/04	"From disease to mechanisms: old and new stories about E-cadherin"	CDR Saint-Antoine (Paris, França)
2012/03	"Epigenetic Changes in Cancer and Epithelial to Mesenchymal Transitions"	Mini-symposium on Epigenetics and Cancer IBMC (Porto, Portugal)
2011/05	"E-cadherin the sticky component of epithelial tissues: old gene new stories"	CEDOC (Lisbon, Portugal)
2011/05	"Tumor cell invasion and metastasis"	I Workshop on Cancer Research: biological and molecular basis (Porto, Portugal)
2011/05	"Regulation of E-cadherin expression and function in cancer"	BIOCANT (Coimbra, Portugal)
2010/09	"Regulatory RNA molecules modulating the function of E-cadherin"	Mini-Symposium on “Mechanisms of Gene Expression IPATIMUP (Porto, Portugal)
2010/04	"Functions of non-coding RNAs in gene regulation and disease"	ICBAS (Porto, Portugal)
2010/04	"Coding and non-coding RNAs controlling E-cadherin expression and function"	“RNA world: not so small” Life Technologies/Applied Biosystems Symposium (Porto, Portugal)
2010/03	"E-cadherin and Hereditary Diffuse Gastric Cancer (HDGC)"	I Meeting on Biomedical Sciences (Aveiro, Portugal)
2009/11	"Functions of non-coding RNAs in gene regulation and disease"	Annual Meeting Portuguese Society of Human Genetics (Porto, Portugal)
2009/06	"Nanoparticles as a vehicle to decrease cancer risk"	Symposium 20 years of Biomagical Engineering (Braga, Portugal)
2009/05	"E-cadherin expression regulation in Cancer: new targets of regulation in the E-cadherin locus”	SINAL 2009 - 3rd Meeting on Signal Transduction (Aveiro, Portugal)
2008/12	"Modulating the expression of E-cadherin (CDH1) in Hereditary Diffuse Gastric Cancer"	IGC (Lisbon, Portugal)
2008/11	"Modulating the expression of E-cadherin (CDH1) in Hereditary Diffuse Gastric Cancer"	Annual Meeting Portuguese Society of Human Genetics SPGH (Lisbon, Portugal)
2008/01	"Gastric cancer"	Seminars in Biopathology. Faculty of Medicine FMUP (Porto, Portugal)
2007/10	"Hereditary Diffuse Gastric Cancer (HDGC): The model of E-Cadherin (CDH1)"	VuMC (Amsterdam, Países Baixos)
2007/03	"BRAF and KRAS activating mutations in colorectal carcinogenesis"	SINAL – 1st National Meeting on Signal Transduction SINAL (Lisbon, Portugal)
2004/05	"KRAS and BRAF in gastrointestinal neoplasia"	INSERM (Paris, França)
2004/05	"Distinct patterns of KRAS mutations in colorectal carcinomas according to germline Mismatch Repair defects and hMLH1 methylation status"	XIII Porto Cancer Meeting: Mismatch repair genes, Microsatellite Instability, and Cancer (Porto, Portugal)
2004/04	"KRAS and BRAF in MSI gastric and colorectal carcinomas"	10th Multidisciplinary Meeting in Oncology (Lisbon, Portugal)
2002/06	"Genetic factors of hereditary gastric cancer"	Meeting on psycho-social and ethical aspects of genetic testing: neurological diseases and hereditary cancer (Porto, Portugal)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2019/10 - Atual	The Primary Genetic Cause and Beyond: Life-Time Risk and Phenotype Modifiers in HDGC Orientador de Ana Rita Matos	Doutoramento (Doutoramento) BiotechHealth Programme, Portugal
2019/01 - Atual	INHERITED PREDISPOSITION TO GASTRIC CANCER: NOVEL SUSCEPTIBILITY GENES AND A MINIMALLY INVASIVE SCREENING STRATEGY IN GERMLINE MUTATION CARRIERS Orientador de Joana Guerra	Doutoramento (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 - Atual	Irene Gullo, Molecular Pathologist interested in exploring the molecular and histolopathological mechanisms underlying the transition between indolent and aggressive phenotypes in CDH1-associated hereditary diffuse gastric cancers. i3S/ULS São João/FMUP, Porto, PT Orientador	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2018/10 - Atual	"SOLVING THE UNSOLVED RARE DISEASES: HEREDITARY DIFFUSE GASTRIC CANCER" Orientador de José Pelaez	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2017/09 - Atual	"DEVELOPMENT OF AN INTEGRATED KNOWLEDGE BASE FOR GASTRIC CANCER" Coorientador de Rúben Rodrigues	Doutoramento (Doutoramento) Universidade do Minho, Portugal
2022 - 2027	João Neto (2022-2027), Junior Researcher using CRISPR screens to uncover new mechanisms of therapy resistance in HER2-positive gastric cancers. Salary funded by a CEEC-FCT individual position. i3S/ The Netherlands Cancer Institute, Porto/Netherlands, PT/NL. Orientador	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2023 - 2025	Ricardo Amorim (2023-2025), Junior Researcher working in the establishment of clinical pathways of care from patients with Rare tumour risk Syndromes and associated care expenditure. Salary funded by the Horizon Europe PREVENTABLE project. i3S, Porto, PT. Orientador	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2023 - 2025	Celina São José (2023-2025), Post-doc fellow addressing the identification of germline mechanisms underlying the missing heritability in Hereditary Gastric Cancer. Salary funded by the Horizon Europe PREVENTABLE project. i3S, Porto, PT. Orientador	Post-doc Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2023 - 2025	Sara Pereira (2023-2025), Project Manager and Researcher interested in Cost-effectiveness analysis for care provided to patients with Rare Tumour Risk Syndromes. Salary funded by the Horizon Europe PREVENTABLE project. i3S, Porto, PT. Orientador de Sara Pereira	EU Project Manager Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2022 - 2025	Daniel Ferreira (2022-2025), Junior Researcher working in the development of organ-on-chip platforms to study diffuse gastric cancer initiation and early cancer biomarkers. Salary funded by the Horizon Europe PREVENTABLE project. i3S, Porto, PT. Orientador	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2021 - 2025	"DEVELOPMENT OF AN ALGORITHM FOR CLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE (VUS) USING A COMBINATION OF IN SILICO, IN VITRO AND IN VIVO STUDY MODELS" Orientador de Silvana Sousa	Universidade do Porto Faculdade de Medicina, Portugal
2021 - 2025	"BIOPREDICTOR: A TOOL TO PREDICT THE OUTCOME OF MOLECULAR ALTERATIONS" Orientador de Marta Ferreira	Universidade do Porto Faculdade de Ciências, Portugal
2020/01 - 2024	"Breaking Barriers and Perceptions: A Path Towards the Increase of Health Professionals Research Engagement" Coorientador de Liliana Sousa	Doutoramento (Doutoramento) Universidade do Minho, Portugal
2018/10 - 2023/07	"UNVEIL CDH1 REGULATORY NETWORK, BEYOND CODING MUTATIONS IN HDGC" Orientador de Celina São José	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2022 - 2023	"DEVELOPMENT OF METHODS AND PIPELINES FOR NGS DATA ANALYSIS" Orientador de Inês Marques	Universidade do Porto Faculdade de Ciências, Portugal
2017/11 - 2022/12	"ADVANCING CANCER RESEARCH: FROM BASIC KNOWLEDGE TO APPLICATION" Orientador de Ana André	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2018/12/01 - 2022/02	TRANSLATION ERRORS: A NEW INSTIGATOR OF GENOMIC INSTABILITY IN CANCER Coorientador de Mafalda Santos	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2021 - 2022	"THE IMPACT OF NONSENSE MEDIATED DECAY ON CTNNA1 VARIANTS IN TUMORIGENESIS AND DIFFERENTIATION" Orientador de André Oliveira	Universidade do Porto Faculdade de Engenharia, Portugal
2019/01/01 - 2022	"SOLVING THE 3D CHROMATIN STRUCTURE OF CDH1 LOCUS TO IDENTIFY DISEASE-ASSOCIATED MECHANISMS" Orientador de Gabriela Almeida	Junior Researcher Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2014/07/01 - 2021/12/14	"A TISSUE ENGINEERING APPROACH TO BUILDING A STOMACH-ON-A-CHIP" Coorientador de Daniel Ferreira	Doutoramento (Doutoramento) Instituto Nacional de Engenharia Biomédica, Portugal
2017/12 - 2021/10	"STUDY OF CONTROL OF PROTEIN ABUNDANCE USING MULTI-OMICS DATA FROM CANCER SAMPLES” Coorientador de Abel Sousa	Doutoramento (Doutoramento) European Bioinformatics Institute, Reino Unido
2017/10 - 2021/04	"LABORATÓRIO NACIONAL DE SEQUENCIAÇÃO E ANÁLISE DE GENOMAS" Orientador de Marta Ferreira	Research Technician (Ref: POCI-01-0145-FEDER-02218) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2017/01 - 2020/09	"DECONSTRUCTING GASTRIC CANCER COLONIZATION: THE INTERPLAY BETWEEN IMMUNE CELLS, GASTRIC CANCER CELLS AND EXTRACELLULAR VESICLES" Orientador de Sara Rocha	Doutoramento (Doutoramento) BiotechHealth Programme, Portugal
2019/02 - 2020/07	"TACKLING CANCER STEM CELLS: A CHALLENGE AND AN OPPORTUNITY TO ADVANCE IN ANTI-CANCER THERAPY" Orientador de Ana Rita Monteiro	Research Fellowship – MSc (Ref: POCI-01-0145-FEDER-016390) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2018/02 - 2020	"TISSUE ENGINEERED 3D MODELS OF GASTRIC WALL FOR PERMEABILITY STUDIES OF DRUG LOADED NANOPARTICLES" Coorientador de Tiago Santos	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2015/12 - 2020	"UNVEILING THE CROSSTALK BETWEEN E-CADHERIN AND CD44-SPLICE VARIANTS AS A NOVEL STRATEGY TO IMPROVE DRUG SENSITIVITY IN GASTRIC CANCER" Orientador de Carla Pereira	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2013/01/01 - 2019/09/06	"BIOENGINEERING 3D MODELS TO DECONSTRUCT THE ROLE OF EXTRACELLULAR MATRIX MICROENVIRONMENT IN GASTRIC CANCER" Coorientador de Bianca Lourenço	Doutoramento (Doutoramento) Instituto Nacional de Engenharia Biomédica, Portugal
2019/01 - 2019/09	3DEMT - UMA PLATAFORMA DE MICROARRAYS EM 3D PARA A ANÁLISE DE ALTO RENDIMENTO DO PAPEL DA MATRIZ EXTRACELULAR NAS TRANSIÇÕES EPITELIAL-MESENQUIMAL EM CANCRO Orientador de Ana Rita Matos	Research Fellowship MSc (Ref: PTDC/BBB-ECT/2518/2014) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2018/07 - 2019/09	"ADVANCING CANCER RESEARCH: FROM BASIC KNOWLEDGE TO APPLICATION" Orientador de Liliana Sousa	Research Fellowship MSc (Ref: NORTE-01-0145-FEDER-000029) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2018/07 - 2019/08	"3DEMT - UMA PLATAFORMA DE MICROARRAYS EM 3D PARA A ANÁLISE DE ALTO RENDIMENTO DO PAPEL DA MATRIZ EXTRACELULAR NAS TRANSIÇÕES EPITELIAL-MESENQUIMAL EM CANCRO" Orientador de Sara Teles	Research Fellowship – BI-L (Ref: PTDC/BBB-ECT/2518/2014) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2019/01 - 2019/07	"IntCDH1 - THE INTRONIC REGULATION OF THE CDH1 GENE" Coorientador de Marta Moreno	Research Fellowship – MSc (Ref: IntCDH1) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2013/09/01 - 2019/03/11	"MORPHOLOGICAL AND IMMUNOPHENOTYPIC HETEROGENEITY IN GASTRIC CANCER" Coorientador de Irene Gullo	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2019	"BIOMARKERS IN GASTRIC CANCER" Coorientador de Silvana Sousa	Mestrado (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/08/01 - 2018/12/31	"CIRCULATING EXOSOMES: A TOOL TO FOLLOW GASTRIC TUMOUR DYNAMICS AND THERAPY RESPONSE" Orientador de Joana Carvalho	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2016/01/01 - 2018/12/31	"EMT/MET IN GASTRIC CANCER: USING NEXT GENERATION SEQUENCING DATA TO UNCOVER NOVEL THERAPEUTIC TARGETS" Orientador de Patricia Oliveira	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2014/03/01 - 2018/12/31	"DISSECTING THE 3D CHROMATIN ARCHITECTURE OF THE CDH1 LOCUS" Orientador de Anabela Ferro	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2014/01/01 - 2018/12/31	"IMPROVING GASTRIC CANCER PATIENT STRATIFICATION TOWARDS PERSONALISED THERAPY" Orientador de Gabriela Almeida	Research Associate with an iFCT contract for 5 years (Project Ref. iFCT2013/00615) Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2017/10 - 2018/12	"MAPPING GENETIC AND PHENOTYPIC HETEROGENEITY IN HER2 POSITIVE CANCERS TO ANTICIPATE AND COUNTERACT RESISTANCE PHENOTYPES" Orientador de Barbara Mesquita	Research Fellowship – MSc (Ref: NORTE-01-0145-FEDER-000029) (Outra) Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2016/04/01 - 2018/11/30	"ARTIFICIAL EXTRACELLULAR MATRIX-LIKE MATRICES AS 3D IN VITRO MODELS TO INVESTIGATE THE ROLE OF THE MICROENVIRONMENT IN CANCER METASTISATION" Coorientador de Silvia Bidarra	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2014/01/01 - 2018/07/11	"INNOVATIVE COLORECTAL CANCER DIAGNOSIS AND TREATMENT WITH ENGINEERED NANOPARTICLES" Coorientador de Patrick Kennedy	Doutoramento (Doutoramento) Instituto Nacional de Engenharia Biomédica, Portugal
2013/02/01 - 2018/02/16	"UNRAVELLING THE ROLES OF STATISTICAL PROTEOMES IN HUMAN CANCER" Coorientador de Mafalda Santos	Doutoramento (Doutoramento) Universidade de Aveiro, Portugal
2016 - 2018	"CLINICAL AND FUNCTIONAL IMPACT OF A CDH1 GENE MUTATION: FROM THE DEFINITION OF A COMMON ANCESTOR TO THE FUNCTIONAL CHARACTERIZATION OF A CAUSATIVE MUTATION" Orientador de Rafaela Silva	Mestrado (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2018	"DISCLOSING HYPOMETHYLATION AS AN ONCOGENE ACTIVATION MECHANISM" Orientador de Sara Teles	Mestrado (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2018	"CDH1 GENOMIC BLUEPRINT: THE ROLE OF ITS CIS-REGULATORY ELEMENTS" Orientador de Ana Rita Matos	Mestrado (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2012/01/02 - 2017/03/27	"UNRAVELLING THE CELLULAR NETWORKS THAT REGULATE PROTEOTOXIC STRESS" Coorientador de Ana Sofia Varanda	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2015 - 2017	"THE GERMLINE AND SOMATIC LANDSCAPE OF FAMILIAL INTESTINAL GASTRIC CANCER: SEARCH FOR A CAUSE" Orientador de Celina São José	Mestrado (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/01/01 - 2016/12/31	"CDH1 EXPRESSION REGULATION: AN ALTERNATIVE MOLECULAR CAUSE FOR HEREDITARY DIFFUSE GASTRIC CANCER" Orientador de Hugo Pinheiro	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2012/01/01 - 2016/12/31	"ADHESION, DIFFERENTIATION AND INVASION: DIFFERENT PROCESSES, COMMON CADHERIN PLAYERS" Coorientador de Ana Sofia Ribeiro	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2013/03/01 - 2016/07/31	"STUDY OF SECRETED CELL VESICLES DURING EPITHELIAL-MESENCHYMAL-EPITHELIAL TRANSITIONS AND THEIR ROLE IN THE CANCER METASTATIC PROCESS" Orientador de Joana Carvalho	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2014 - 2016	"HEREDITARY DIFFUSE GASTRIC CANCER BEYOND CDH1 CODING MUTATIONS" Orientador de Hugo Pinheiro	Mestrado (Mestrado) Universidade do Minho Escola de Medicina, Portugal
2014 - 2016	"CHARACTERIZATION OF AN E-CADHERIN-RELATED COMMON ANCESTOR IN HEREDITARY DIFFUSE GASTRIC CANCER FAMILIES FROM THE NORTHERN PORTUGAL" Orientador de Ana Aguiar	Mestrado (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2014 - 2016	"CDH1 REGULATORY VARIANTS AND HEREDITARY DIFFUSE GASTRIC CANCER" Orientador de Ana Sofia Valente	Mestrado (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2013/01/31 - 2015/12/31	"ALL TOGETHER NOW: COMBINED INFLUENCE OF E-CADHERIN MODULATORS IN EPITHELIAL-MESENCHYMAL-EPITHELIAL TRANSITIONS AND CANCER PROGRESSION" Orientador de Patricia Oliveira	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2013 - 2015	"KRAS MUTATIONS IN MICROSATELLITE INSTABLE GASTRIC TUMOURS: IMPACT OF TARGETED TREATMENT AND INTRATUMOURAL HETEROGENEITY" Orientador de Pedro Queirós	Mestrado (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2012/01/01 - 2014/12/31	"CDH1 LOCUS, THE NEXT JEKYLL AND HYDE IN CANCER?" Orientador de Hugo Pinheiro	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2012 - 2014	"DIES1 GENE EXPRESSION AND REGULATION IN GASTRIC CANCER" Orientador de Inês Reis	Mestrado (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/04/01 - 2013/12/31	"TARGETING CHEMOTHERAPY-INDUCED EMT AND CANCER STEM CELLS FOR OVERCOMING TUMOUR DRUG RESISTANCE" Orientador de Gabriela Almeida	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2011/01/09 - 2013/03/31	"NEW E-CADHERIN RNAS: THE DARK SIDE OF A TUMOUR SUPPRESSOR GENE" Orientador de Denisa Mateus	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2009/02/01 - 2013/03/18	"SUPPRESSOR-TRNAS AS THERAPEUTIC TOOLS FOR CANCER ASSOCIATED SYNDROMES: HDGC AS A MODEL SYSTEM" Orientador de Renata Bordeira-Carriço	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2010/01/01 - 2012/12/31	"FUNCTIONAL GENOMICS OF RIBOSOME INFIDELITY PHENOTYPES ASSOCIATED TO HUMAN DISEASES" Orientador de Patricia Pereira	Post-Doctoral Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2012/01/01 - 2012/12/07	"THE INVOLVEMENT OF MICRORNAS IN GASTRIC CANCER" Orientador de Joana Carvalho	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2010 - 2012	"EXPRESSION ANALYSIS OF MICRORNAS TARGETING ADHESION COMPLEX MOLECULES IN GASTRIC CANCER" Orientador de Pedro Freitas	Mestrado (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2010 - 2012	"AN IN VITRO MODEL OF EMT/MET USING HUMAN NEAR-NORMAL AND CANCER-DERIVED BREAST CELL LINES" Orientador de Mafalda Azevedo	Mestrado (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 - 2011/12/22	"E-CADHERIN: NEW REGULATORY MECHANISMS IN CANCER" Orientador de Hugo Pinheiro	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2007/01/01 - 2010/12/31	"IDENTIFICATION OF NOVEL CIS-REGULATORY ELEMENTS IN THE CADHERIN SUPERFAMILY AND CHARACTERIZATION OF THEIR ROLE IN CANCER-RELATED PROCESSES" Orientador de Patricia Oliveira	Doutoramento (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006/01/01 - 2010/05/31	"THE ROLE OF BRAF AND KRAS ACTIVATING MUTATIONS IN DEFICIENT AND PROFICIENT MMR COLORECTAL CARCINOMAS" Coorientador de Sérgia Velho	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2006/01/01 - 2010/04/13	"EPIGENETIC, GENETIC AND FUNCTIONAL ANALYSES OF MICRORNA-MACHINERY IN HUMAN CANCER" Coorientador de Sónia Melo	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2005/01/01 - 2008/12/02	"THE ROLE OF NONSENSE-MEDIATED MRNA DECAY (NMD) IN THE REGULATION OF CDH1 GENE EXPRESSION AND CANCER DEVELOPMENT" Orientador de Rachid Karam	Doutoramento (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2005 - 2007	"E-CADHERIN SILENCING: MORE THAN INACTIVATING MUTATIONS" Orientador de Hugo Pinheiro	Mestrado (Mestrado) Universidade do Minho, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2024 - Atual	Organizer and Chair if the Scientific Program Committee of the 5th International Gastric Cancer Linkage Consortium (IGCLC) meeting 2024, Porto, Portugal. (2024/06 - 2024/06)	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2023 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics 2023, Lisbon, Portugal. (2023/11 - 2023/11)	Sociedade Portuguesa de Genética Humana, Portugal
2022 - Atual	Organizer of the Workshop - European Reference Networks - More than just a wish? in the European Human Genetics Conference (ESHG) 2022, Vienna, Austria. (2022/06 - 2022/06)	European Society of Human Genetics, Áustria
2022 - Atual	Organizer and Scientific Program Committee Member of the European Human Genetics Hybrid Conference ESHG 2022, Vienna, Austria. (2022/06 - 2022/06)	European Society of Human Genetics, Áustria
2022 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics 2022, Coimbra, Portugal. (2022/11 - 2022/11)	Sociedade Portuguesa de Genética Humana, Portugal
2021/11 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics 2021, Porto, Portugal. (2021)	Sociedade Portuguesa de Genética Humana, Portugal
2021/08 - Atual	Organizer and Scientific Program Committee Member of the European Human Genetics Virtual Conference ESHG 2021. (2021)	European Society of Human Genetics, Áustria
2020/11 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics 2020, Porto, Portugal. (2020)	Sociedade Portuguesa de Genética Humana, Portugal
2020/06 - Atual	Organizer of the Workshop ¿W06 - European Reference Networks "What is in it for me?". European Human Genetics Virtual Conference ESHG 2020.2 - Live in Your Living Room. (2020)	European Society of Human Genetics, Áustria
2020/06 - Atual	Organizer and Scientific Program Committee Member of the European Human Genetics Virtual Conference ESHG 2020.2 - Live in Your Living Room. (2020)	European Society of Human Genetics, Áustria
2019/11 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics 2019, Porto, Portugal. (2019/11 - 2019/11)	Sociedade Portuguesa de Genética Humana, Portugal
2016/04 - Atual	Co-Organizer of the “Spring Course in Hereditary Cancer Genetics”. Bertinoro, Italy. (2016/04) Outro (Coorganizador)	European Society of Human Genetics, Áustria
2010/11 - Atual	Organizer and Chair of the Scientific Program Committee of the Portuguese Society of Human Genetics (2010) Congresso (Membro da Comissão Científica)	Sociedade Portuguesa de Genética Humana: SPGH, Portugal
2010/06 - Atual	Organizer and Scientific Program Committee Member of the European Human Genetics Conference (2010/06) Congresso (Membro da Comissão Científica)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2023 - 2023	Organizer and Scientific Program Committee Member of the European Human Genetics Hybrid Conference ESHG 2023, Glasgow, Scotland. (2023/06)	European Society of Human Genetics, Áustria
2019/11 - 2019/11	Organizer of the Workshop ¿Genetic and Oncology: building bridges. 16th National Congress of Oncology 2019 (2019/11 - 2019/11) Oficina (workshop)	Sociedade Portuguesa de Oncologia, Portugal
2019/06 - 2019/06	Organizer of the Workshop “European Reference Networks – What is in it for me?”. European Human Genetics Conference (ESHG) 2019. Gothenburg, Sweden (2019/06 - 2019/06) Oficina (workshop) (Coorganizador)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2018/11 - 2018/11	Organizer of the Workshop: “What are ERNs and what is in there for me?”. Satellite Meeting-European Reference Networks in Portugal on the 22nd Annual Meeting SPGH. Porto, Portugal. (2018/11 - 2018/11) Oficina (workshop) (Coorganizador)	Sociedade Portuguesa de Genética Humana: SPGH, Portugal
2018/05 - 2018/05	Organizer of the workshop “Presentation of the European Reference Network GENTURIS - Genetic tumour risk syndromes: opportunities to improve health care for patients with hereditary cancer syndromes in Europe”. 3rd ASPIC International Congress, Lisbon, Portugal. (2018/05 - 2018/05) Oficina (workshop) (Coorganizador)	Associação Portuguesa de Investigação em Cancro, Portugal Sociedade Portuguesa de Oncologia, Portugal
2014/10 - 2014/10	Chair of the Session “Gastric cancer: New insights into pathogenesis and management”. UEG – United European Gastroenterology Week, Vienna Austria (2014/10 - 2014/10) Seminário (Outra)	United European Gastroenterology, Áustria
2014/10 - 2014/10	Chair of the Session: Mechanisms underlying the development of GI cancer¿. UEG ¿ United European Gastroenterology Week, Vienna Austria (2014/10 - 2014/10) Seminário (Outra)	United European Gastroenterology, Áustria
2014/10 - 2014/10	Chair of the Session “Clinical perspectives on gastric malignant tumours”. UEG – United European Gastroenterology Week, Vienna Austria (2014/10 - 2014/10) Seminário (Outra)	United European Gastroenterology, Áustria Sociedade Portuguesa de Oncologia, Portugal
2011/05 - 2011/05	Chair of the “Cancer Genetics” session, The European Human Genetics Conference 2011. Amsterdam, The Netherlands. (2011/05 - 2011/05) Seminário (Outra)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2011/05 - 2011/05	Chair of the "Cancer Genomes" session, The European Human Genetics Conference 2011. Amsterdam, The Netherlands. (2011/05 - 2011/05) Seminário (Outra)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2010/09 - 2010/09	Organizer of the RNA Symposium- 17th National Congress of Biochemistry. Porto, Portugal. (2010/09 - 2010/09) Simpósio (Membro da Comissão Organizadora)	Sociedade Portuguesa de Oncologia, Portugal
2010/06 - 2010/06	Chair of the “Cancer Genetics” session, The European Human Genetics Conference 2010. Gothenburg, Sweden. (2010/06 - 2010/06) Seminário (Outra)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2010/06 - 2010/06	Chair of the “Long Distance Regulation session”, The European Human Genetics Conference 2010. Gothenburg, Sweden. (2010/06 - 2010/06) Seminário (Outra)	European Society of Human Genetics, Áustria Sociedade Portuguesa de Oncologia, Portugal
2010/05 - 2010/05	Chair of the SINAL 2010 – 4th National Meeting on Signal Transduction. Univ. of Algarve; Portugal. (2010/05 - 2010/05) Encontro (Outra)	Universidade do Algarve, Portugal
2009/05 - 2009/05	Chair of the SINAL 2009 - 3nd National Meeting on Signal Transduction. Univ. of Aveiro, Portugal. (2009/05 - 2009/05) Encontro (Outra)	Universidade de Aveiro, Portugal
2008/05 - 2008/05	Organizer of the SINAL 2008 – 2nd National Meeting on Signal Transduction. Institute for Molecular and Cell Biology (IBMC), Porto, Portugal. (2008/05 - 2008/05) Encontro (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2004/05 - 2004/05	Organizer of the XIII Edition Porto Cancer Meeting "Mismatch repair genes, Microsatellite instability, and Cancer". IPATIMUP; Porto, Portugal. (2014/05 - 2014/05) Encontro (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2002/05 - 2002/05	Organizer of the XI Edition Porto Cancer Meeting “Familial and hereditary gastric cancer – Meeting of the International Gastric Cancer Linkage Consortium (IGCLC)”. IPATIMUP; Porto, Portugal. (2002/05 - 2002/05) Encontro (Membro da Comissão Organizadora)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2023	Invited Jury member (examiner): PhD Dissertation of Marta Cardoso, ICBAS, Portugal Arguente	Marta Cardoso (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023	Invited Jury member (examiner): Masters Dissertation of João Nogueira, Univ. of Minho, Portugal Arguente principal	João Nogueira (Mestrado) Universidade do Minho, Portugal
2023	Invited Jury member (examiner): Masters Dissertation of Cláudia Fernandes, FCUP/ICBAS, Portugal Arguente principal	Cláudia Fernandes (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022	Invited Jury member: Ph.D. Thesis of Miguel Silva, ICBAS, Portugal Arguente	Miguel Silva (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022	Member of the Ph.D. Dissertation Committee of Joana Teixeira, ICBAS, Portugal Arguente	Joana Teixeira (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022	Invited Jury member (examiner): Masters Dissertation of Patrícia Carvalho, ICBAS, Portugal Arguente	Patricia Carvalho (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022	Invited Jury member: Masters Dissertation of Marco Cruz, ICBAS, Portugal Arguente	Marco Cruz (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021	Member of the Ph.D. Dissertation Committee of Abel Sousa, FCUP, Portugal Orientador	Abel Sousa (Doutoramento) Universidade do Porto Faculdade de Ciências, Portugal
2021	Member of the Ph.D. Dissertation Committee of Daniel Ferreira, ICBAS, Portugal Orientador	Daniel Ferreira (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021	Member of the Masters Dissertation Committee of Francisco Almeida, FCUP, Portugal Orientador	Francisco Almeida (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2021	Invited Jury member (examiner): Masters Dissertation of Ana Abreu, Univ. Aveiro, Portugal Arguente	Ana Abreu (Mestrado) Universidade de Aveiro, Portugal
2021	Invited Jury member (examiner): Ph.D. Thesis of Joana Maia, ICBAS, Portugal Arguente	Joana Maia (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020	Member of the Ph.D. Dissertation Committee of Sara Rocha, ICBAS, Portugal; Biotechnology Orientador	Sara Rocha (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020	Member of the Ph.D. Dissertation Committee of Carla Pereira, FMUP, Portugal Orientador	Carla Pereira (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2019	Member of the Ph.D. Dissertation Committee of Bianca Lourenço, FEUP, Portugal; Nanomedicine Orientador	Bianca Lourenço (Doutoramento) Universidade do Porto Faculdade de Engenharia, Portugal
2019	Member of the Ph.D. Dissertation Committee of Mafalda Matos, FMUL, Portugal; Oncobiology Orientador	Mafalda Matos (Doutoramento) Universidade de Lisboa Faculdade de Medicina, Portugal
2018	Invited Jury member (examiner): Ph.D. Thesis of Ricardo Pais, IGC, Portugal; Computational Biology Arguente	Ricardo Pais (Doutoramento) Instituto Gulbenkian de Ciência, Portugal
2018	Member of the Masters Dissertation Committee of Ana Rita Matos, Univ. Porto, Portugal; Gene Regulation Orientador	Ana Rita Matos (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2018	Member of the Masters Dissertation Committee of Sara Teles, Univ. Porto, Portugal; Oncobiology Orientador	Sara Teles (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018	Member of the Ph.D. Dissertation Committee of Joana Nunes. Univ. Porto, Portugal; Oncobiology Arguente	Joana Nunes (Doutoramento) Universidade do Porto, Portugal
2018	Member of the Masters Dissertation Committee of Rafaela Silva, Univ. Porto, Portugal; Human Genetics Orientador	Rafaela Silva (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2018	Invited Jury member (examiner): Masters Dissertation of Bárbara Alves. Univ. Porto, Portugal; Biology Arguente principal	Bárbara Alves (Mestrado) Universidade do Porto, Portugal
2018	Invited Jury member (examiner): Ph.D. Thesis of Joana Lima. Univ. Porto, Portugal; Nanomedicine Arguente	Joana Lima (Doutoramento) Universidade do Porto, Portugal
2017	Invited Jury member (examiner): Masters Dissertation of Ricardo Cunha. Univ. Porto, Portugal; Biology Arguente principal	Ricardo Cunha (Mestrado) Universidade do Porto, Portugal
2017	Member of the Masters Dissertation Committee of Celina São José. Univ. Porto, Portugal; Human Genetics Orientador	Celina São José (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2017	Invited Jury member (examiner): Ph.D. Dissertation of Ana Metelo. Univ. Coimbra, Portugal; Biology Arguente	Ana Metelo (Doutoramento) Universidade de Coimbra, Portugal
2017	Invited Jury member (Pre-examiner): Ph.D. Thesis of Elisa Lazaro Ibanez. Univ. Helsinki; Biology Arguente	Elisa Lazaro Ibanez (Doutoramento) Helsingin yliopisto, Finlândia
2017	Member of the Ph.D. Dissertation Committee of Ana Sofia Varanda. Univ. Aveiro, Portugal; Biology Orientador	Ana Sofia Varanda (Doutoramento) Universidade de Aveiro, Portugal
2016	Member of the Masters Dissertation Committee of Ana Aguiar. Univ. Porto, Portugal; Human Genetics Orientador	Ana Aguiar (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2016	Invited Jury member (examiner): Ph.D. Dissertation of Suellen Ferro. Univ. Porto, Portugal; Oncobiology Arguente	Suellen Ferro (Doutoramento) Universidade do Porto, Portugal
2015	Invited Jury member (examiner): Masters Dissertation of Diana Pinto. Univ. Porto, Portugal; Biology Arguente principal	Diana Pinto (Mestrado) Universidade do Porto, Portugal
2015	Invited Jury member (examiner): Masters Dissertation of Rita Faria. Univ. Porto, Portugal; Gene Regulation Arguente principal	Rita Faria (Mestrado) Universidade do Porto, Portugal
2015	Member of the Ph.D. Dissertation Committee of Bruno Albuquerque. Univ. Porto, Portugal; Gene Regulation Arguente	Bruno Albuquerque (Doutoramento) Universidade do Porto, Portugal
2015	Member of the Ph.D. Dissertation Committee of João Curado e Silva. Univ. Porto, Portugal; Bioinformatics Arguente	João Curado Silva (Doutoramento) Universidade do Porto, Portugal
2015	Member of the Ph.D. Dissertation Committee of Joana Santos. Univ. Porto, Portugal; Biology Arguente	Joana Santos (Doutoramento) Universidade do Porto, Portugal
2015	Member of the Masters Dissertation Committee of Pedro Queirós. Univ. Porto, Portugal; Oncobiology Orientador	Pedro Queirós (Mestrado) Universidade do Porto, Portugal
2015	Member of the Ph.D. Dissertation Committee of Margherita Francescatto. Univ. Porto, Portugal; Biology Arguente	Margherita Francescatto (Doutoramento) Universidade do Porto, Portugal
2014	Member of the Ph.D. Dissertation Committee of Germana Domingues. Univ. Lisbon, Portugal; Biology Arguente	Germana Domingues (Doutoramento) Universidade Autónoma de Lisboa, Portugal
2014	Invited Jury member (examiner): Ph.D. Dissertation of Joana Costa. Univ. Lisbon, Portugal; Biology Arguente principal	Joana Costa (Doutoramento) Universidade Autónoma de Lisboa, Portugal
2014	Member of the Ph.D. Dissertation Committee of Irina Amorim. Univ. Porto, Portugal; Glycobiology Arguente	Irina Amorim (Doutoramento) Universidade do Porto, Portugal
2014	Invited Jury member (examiner): Masters Dissertation of João Coentro. Univ. Porto, Portugal; Bioinformatics Arguente principal	João Coentro (Mestrado) Universidade do Porto, Portugal
2014	Member of the Masters Dissertation Committee of Inês Reis. Univ. Porto, Portugal; Oncobiology Orientador	Inês Reis (Mestrado) Universidade do Porto, Portugal
2014	Invited Jury member (examiner): Masters Dissertation of Rui Barranha. Univ. Porto, Portugal; Oncobiology Arguente principal	Rui Barranha (Mestrado) Universidade do Porto, Portugal
2014	Invited Jury member (examiner): Ph.D. Dissertation of Ana Ramos. Univ. Coimbra, Portugal; Biology Arguente	Ana Ramos (Doutoramento) Universidade do Porto, Portugal
2013	Member of the Ph.D. Dissertation Committee of Bruno Pereira. Univ. Porto, Portugal Arguente	Bruno Pereira (Doutoramento) Universidade do Porto, Portugal
2013	Invited Jury member (examiner): Ph.D. Dissertation of Pedro Costa. Univ. Coimbra, Portugal; Oncobiology Arguente principal	Pedro Costa (Doutoramento) Universidade de Coimbra, Portugal
2013	Member of the Ph.D. Dissertation Committee of Renata Bordeira-Carriço. Univ. Porto, Portugal; Human Genetics Orientador	Renata Bordeira-Carriço (Doutoramento) Universidade do Porto, Portugal
2013	Invited Jury member (examiner): Ph.D. Dissertation of Cristovão Sousa. L’Université Pierre et Marie Curie. Paris, France; Biology Arguente principal	Cristovão Sousa (Doutoramento) Sorbonne Université Campus Pierre et Marie Curie, França
2012	Member of the Ph.D. Dissertation Committee of Joana Carvalho. Univ. Porto, Portugal; Oncobiology Orientador	Joana Carvalho (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2012	Invited Jury member (examiner): Masters Dissertation of Diana Sobral Mesquita. Univ. Porto, Portugal; Biology Arguente	Diana Sobral Mesquita (Mestrado) Universidade do Porto, Portugal
2012	Member of the Masters Dissertation Committee of Mafalda Azevedo. Univ. Porto, Portugal; Biology Orientador	Mafalda Azevedo (Mestrado) Universidade do Porto, Portugal
2012	Invited Jury member (examiner): Ph.D. Dissertation of Inês Almeida. ICVS - Universidade do Minho. Braga, Portugal; Oncobiology Arguente principal	Inês Almeida (Doutoramento) Universidade do Minho, Portugal
2012	Invited Jury member (examiner): Ph.D. Dissertation of Fatiha Sangar. L’Université Pierre et Marie Curie. Paris, France; Oncobiology Arguente principal	Fatiha Sangar (Doutoramento) Sorbonne Université Campus Pierre et Marie Curie, França
2012	Member of the Ph.D. Dissertation Committee of Giovanni Corso. Univ. Porto, Portugal; Oncobiology Arguente	Giovanni Corso (Doutoramento) Universidade do Porto, Portugal
2012	Invited Jury member (examiner): Ph.D. Dissertation of Joana Domingues. Univ. Porto, Portugal; Gene Regulation Arguente	Joana Domingues (Doutoramento) Universidade do Porto, Portugal
2011	Invited Jury member (examiner): Ph.D. Dissertation of Bruno Cardoso. Univ. Lisbon, Portugal; Oncobiology Arguente principal	Bruno Cardoso (Doutoramento) Universidade Autónoma de Lisboa, Portugal
2011	Member of the Ph.D. Dissertation Committee of Hugo Pinheiro. Univ. Porto, Portugal; Human Genetics Orientador	Hugo Pinheiro (Doutoramento) Universidade do Porto, Portugal
2011	Member of the Ph.D. Dissertation Committee of Joana Fernandes. Univ. Porto, Portugal; Biology Arguente	Joana Fernandes (Doutoramento) Universidade do Porto, Portugal
2011	Member of the Ph.D. Dissertation Committee of Denisa Mateus. Univ. Aveiro, Portugal; Biology Arguente principal	Denisa Mateus (Doutoramento) Universidade de Aveiro, Portugal
2010	Invited Jury member (examiner): Masters Dissertation of Rita Domingues. Univ. Porto, Portugal; Gene Regulation Arguente	Rita Domingues (Mestrado) Universidade do Porto, Portugal
2010	Member of the Ph.D. Dissertation Committee of Sérgia Velho. Univ. Porto, Portugal; Oncobiology Orientador	Sérgia Velho (Doutoramento) Universidade do Porto, Portugal
2010	Member of the Ph.D. Dissertation Committee of Sónia Melo. Univ. Porto, Portugal; Oncobiology Orientador	Sónia Melo (Doutoramento) Universidade do Porto, Portugal
2009	Invited Jury member (examiner): Masters Dissertation of Filipa Sousa. Univ. Porto, Portugal; Human Genetics Orientador	Filipa Sousa (Mestrado) Universidade do Porto, Portugal
2009	Member of the Ph.D. Dissertation Committee of Joana Simões-Correia. Univ. Porto, Portugal; Oncobiology Arguente	Joana Simões-Correia (Doutoramento) Universidade do Porto, Portugal
2009	Member of the Ph.D. Dissertation Committee of Ana Rita Mateus. Univ. Porto, Portugal; Oncobiology Arguente	Ana Rita Mateus (Doutoramento) Universidade do Porto, Portugal
2008	Invited Jury member (examiner): Ph.D. Dissertation of Ana Paula Elias. Univ. Lisbon, Portugal; Oncobiology Arguente principal	Ana Paula Elias (Doutoramento) Universidade Autónoma de Lisboa, Portugal
2008	Member of the Ph.D. Dissertation Committee of Rachid Karam. Univ. Porto, Portugal; Human Genetics Orientador	Rachid Karam (Doutoramento) Universidade do Porto, Portugal
2007	Invited Jury member (examiner): Masters Dissertation of Renata Carriço. Univ. Lisbon, Portugal; Human Genetics Arguente principal	Renata Carriço (Mestrado) Universidade Autónoma de Lisboa, Portugal
2007	Member of the Ph.D. Dissertation Committee of Catarina Castro Alves. Univ. Porto, Portugal; Oncobiology Arguente	Catarina Castro Alves (Doutoramento) Universidade do Porto, Portugal

Comissão de avaliação

Consultoria / Parecer

	Descrição da atividade	Instituição / Organização
2002 - Atual	PEER REVIEW JOURNALS: Journal of Pathology; Oncogene; BMC Cancer; Annals of Human Genetics; European Journal of Human Genetics; Cellular Oncology; Familial Cancer; Future Oncology; Clinical Genetics; European Journal of Cancer; International Journal of Cancer; Carcinogenesis; Virchows Archives; World journal of Gastroenterology; Epigenomics; PlosOne; BMC Genomics; Human Molecular Genetics; Genome Research; Lancet Oncology; Gastroenterology; Frontiers in Genetics; Journal of Medical Genetics
2002 - Atual	FUNDING AGENCIES: Health Research Council of New Zealand; European Research Council Executive Agency; ICS-Institut Clinique de la Souris, France; Dutch Cancer Society (KWF Kankerbestrijding); Portuguese Foundation of Science and Technology (FCT): Research Projects, PhD and Post-doc grant applications (http://www.fct.pt /apoios/bolsas/concursos/ membros?idc=28&idav=38&idp={8AB5E1CF-5699-4213-966A-C2E899921CB0}&show=elems)

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2022 - Atual	Responsible for the curricular unit "Biomedical and Bioinformatics Research I" in the 1st Degree in Digital Health and Biomedical Innovation from FMUP, Univ. Porto, Porto PT	(Licenciatura)	Universidade do Porto Faculdade de Medicina, Portugal
2022 - Atual	Co-responsible for the curricular unit "Biomedical and Bioinformatics Research II" in the 1st Degree in Digital Health and Biomedical Innovation from FMUP, Univ. Porto, Porto PT	(Licenciatura)	Universidade do Porto Faculdade de Medicina, Portugal
2022 - Atual	Co-responsible for the curricular unit "Project in Human Biology" in the 1st Degree in Digital Health and Translational Medicine from FMUP, Univ. Porto, Porto PT	(Licenciatura)	Universidade do Porto Faculdade de Medicina, Portugal
2019 - Atual	Faculty and Supervisor, PhD Programme in Business Administration, Univ. Minho, Braga, PT	(Doutoramento)	Universidade do Minho, Portugal
2019 - Atual	Faculty and Supervisor, Doctoral Program in Molecular and Cell Biology (MCbiology), ICBAS, Univ. Porto, PT	(Doutoramento)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - Atual	Faculty and co-Organizer, European Society of Human Genetics-ESHG Biennial Course in Hereditary Cancer Genetics, Univ. Residential Centre Bertinoro, IT	(Outros)	European Society of Human Genetics, Áustria
2014 - Atual	Faculty and Supervisor, BiotechHealth - Doctoral Program on Cellular and Molecular Biotechnology Applied to Health Sciences, Porto, PT	(Doutoramento)	BiotechHealth Programme, Portugal
2011 - Atual	Faculty, Ipatimup, “Genomics and Transcriptomics”, Workshop in Cancer Research. Porto, PT	(Outros)	Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2008 - Atual	Faculty and Supervisor, Oncology Master Program, ICBAS, Porto, PT	(Mestrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 - Atual	Faculty and Supervisor, Doctoral Program in Molecular Medicine and Oncology (PDMOM), FMUP, Univ. Porto, PT	(Doutoramento)	Universidade do Porto Faculdade de Medicina, Portugal
2005 - Atual	Faculty and Supervisor, Medicine and Molecular Oncology Master (MOM) Program, FMUP, Porto, PT	(Mestrado)	Universidade do Porto Faculdade de Medicina, Portugal
2005 - Atual	Faculty and Supervisor, Biomedicine Doctoral Program, FMUP, Porto, PT	(Doutoramento)	Universidade do Porto Faculdade de Medicina, Portugal
2004 - Atual	Faculty and Supervisor, GABBA PhD Program, Univ. Porto, PT	(Doutoramento)	Universidade do Porto, Portugal
2017 - 2019	Faculty and Supervisor, Bioinformatics Master Program, Univ. Minho, Braga, PT	(Mestrado)	Universidade do Minho, Portugal
1995 - 1996	Monitor (volunteer), practical lessons of Molecular Biology delivered to of Biochemistry and Biology undergraduate students	(Curso de Especialização Tecnológica)	Universidade de Coimbra, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2017 - Atual	Sociedade Portuguesa de Genética - SPG	Member
2016 - Atual	European Society for Medical Oncology – ESMO	Member
2014 - Atual	Portuguese Association for Cancer research – ASPIC	Member
2014 - Atual	Grupo Español de Investigation en Vesículas Extracelulares - GEIVEX	Member
2014 - Atual	European Association for Cancer research – EACR	Member
2013 - Atual	European Society of Human Genetics – ESHG	Deputy Secretary General and Scientific Program Committee member
2003 - Atual	Portuguese Society of Human Genetics - SPGH	Chair of the Scientific Program Committee

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2023 - Atual	Vice-representative of Centro Hospitalar Universitário S. João (CHUSJ, Porto, PT) ERN-GENTURIS (European Reference Network on Tumour Risk Syndromes) Coordenador	GENTURIS - European Reference Network (ERN), Países Baixos
2023 - Atual	Member, Travel Fellowships Committee, European Association for cancer Research (EACR)	European Association For Cancer Research, Reino Unido
2022 - Atual	Organizing Committee Member, INTERNATIONAL GASTRIC CANCER CONGRESS 2022 https://gastriccancerconference.com/general-information/committees/ Membro	International Gastric Cancer Association, Estados Unidos
2022 - Atual	Co-Responsible of three curricular units, Degree in Digital Health and Biomedical Innovation, FMUP, UP, PT	Universidade do Porto Faculdade de Medicina, Portugal
2021 - Atual	Review Panel Member, Research grants Bolsa Terry Fox – Liga Portuguesa contra o cancro, PT	Liga Portuguesa Contra o Cancro, Portugal
2017 - Atual	Editorial Board member, Applied Cancer Research, BMC-Springer Nature	Biomed Central Ltd, Reino Unido
2016 - Atual	Working Group Member, ClinGen Genomic Clinical Variant Expert Curation Panel for CDH1 gene \| www.clinicalgenome.org/working-groups/clinical-domain/sub-groups/cancer/cdh1-expert-panel/	Clinical Genome Resource, Reino Unido
2014 - Atual	Founding Member and National Representative, European Reference Network on “ERN Genetic tumour risk syndromes - GENTURIS” \| www.genturis.eu	Genetic Tumour Risk Syndrome, Países Baixos
2023 - 2026	Member of the Scientific Advisory Board – 2nd mandate, Integrated Cancer Research Site (Siric) Curamus, Sorbonne Université, Paris, FR	Association Sorbonne Université, França
2022 - 2025	President, SPGH – Portuguese Society of Human Genetics \| http://spgh.net/	Sociedade Portuguesa de Genética Humana, Portugal
2024 - 2024	Local host and Scientific Committee Member, HUGO 15th International Symposium of Variants in the Genome, 13-15 May 2024, Porto, PT\| https://isv.variome.org	Human Genome Organisation, Estados Unidos
2024 - 2024	Co-chair of the 5th International Gastric Cancer Linkage Consortium (IGCLC) meeting, 13-15 June 2024, Porto, PT \| https://www.i3s.up.pt/event.php?v=304 Coordenador	Universidade do Porto Instituto de Investigacao e Inovacao em Saude, Portugal
2022 - 2022	Coordinator of the Evaluation Panel on Experimental Biology and Biochemistry for PhD studentships selection, Portuguese Foundation for Science and technology, PT
2021 - 2022	Member of the Portuguese Group of Hereditary Tumours (PROGO) promoted by The Portuguese Society of Oncology	Sociedade Portuguesa de Oncologia, Portugal
2017 - 2022	Scientific Programme Committee Member, ESHG \| https://www.eshg.org/spc.0.html	European Society of Human Genetics, Áustria
2017 - 2020	Scientific Programme Committee Member, XLI Jornadas Portuguesas de Genética SPG \| https://jornadasgenetica17.wixsite.com/ibimed/committees	Sociedade Portuguesa de Genética, Portugal
2019 - 2019	Member of the Scientific Advisory Board, Integrated Cancer Research Site (Siric) Curamus	Sorbonne Université, França
2018 - 2019	Member of the Committee for the Implementation of European Reference Centers in Portugal, Appointed by the Portuguese Ministry of Health	Ministério da Saúde, Portugal
2018 - 2018	Scientific Committee Member, ASPIC - 3rd ASPIC International Congress \| http://3rdcongress.aspic.pt/congress-commitees	Associação Portuguesa de Investigação em Cancro, Portugal
2017 - 2018	Faculty member, Cancer Genetics group, European Society for Medical Oncology ESMO	European Society for Medical Oncology, Suiça
2017 - 2017	Faculty member, Inherited Cancer, 25th United European Gastroenterology Week 2017	United European Gastroenterology, Áustria
2017 - 2017	Scientific Committee Member, Conference “Risco Familiar de Cancro” \| www.ligacontracancro.pt/risco-familiar-de-cancro	Liga Portuguesa Contra o Cancro, Portugal
2017 - 2017	Scientific Committee Member, SINAL 2017 8th Meeting on Signal Transduction	Associação Portuguesa de Investigação em Cancro, Portugal
2015 - 2017	Scientific Committee Member, Grupo Español Investigación Vesículas Extracelulares, GEIVEX	Grupo Español de investigacion en Vesiculas Extracelulares, Espanha
2014 - 2014	Scientific Committee Member, ASPIC \| 1st ASPIC International Congress	Associação Portuguesa de Investigação em Cancro, Portugal

Distinções

Prémio

2024	Honorable Mention "8th Edition Prémio Rui Osório de Castro / Millennium BCP" 2024 for the project "SAPO: Paediatric sarcomas and organoids: new diagnostic biomarkers".
2023	SPGH Meeting "Prémio Investigação Clinica 2023" for best presentation on "An Insight on the Origins of Hereditary Diffuse Gastric Cancer Through Organoid Driven Organ On-A-Chip Technology" (to Daniel Ferreira; Carla Oliveira senior author)
2023	SPGH Meeting "Prémio Investigação Básica 2023" for best presentation on "The CDH1 Regulatory Blueprint: Shaping Hereditary Diffuse Gastric Cancer" (to Celina S. José; Carla Oliveira Senior Author)
2023	Maria de Sousa Award 2023 on "Using Genome-Wide Crispr Genetic Screens to Dissect the Molecular Mechanisms Underlying Therapy Resistance and Sensitivity in Her2-Positive Gastric Cancer". Fundação Bial (to João Neto; Carla Oliveira member of the team)
2022	International 3Rs Prize – Awarded by the National Centre for the Replacement, Refinement & Reduction of Animals in Research, 2022, UK (to Daniel Ferreira and Carla Oliveira)
2022	SPGH Professor Amândio Tavares 2022 Award for the oral presentation entitled “CTNNA1 germline variants: disease spectrum extending beyond Hereditary Diffuse Gastric Cancer” (to Silvana Lobo; Carla Oliveira senior author)
2022	SPGH Meeting “ESHG National Fellowship 2022” for best presentation on “Disruption of regulatory elements in the CDH1 vicinity as a potential HDGC cause, increased penetrance and early onset cancer” (to Celina S. José; Carla Oliveira senior author)
2021	SPGH Professor Amândio Tavares 2021 Award for the oral presentation entitled “The First CDH1 Founder Variant in the Portuguese Population: A Missense with severe Impact in mRNA Splicing” (to Rita Barbosa-Matos; Carla Oliveira senior author)
2021	3rd Best Poster session from XIII National Meeting of Biochemistry Students for the project entitle "Characterization of CDH1 and its Antisense Gene in Stomach and Breast Normal Cell Lines" (to Nelson Martins; Carla Oliveira senior author)
2021	Alfredo da Silva Award 2021 on "Sustainability of Health Systems" for the project entitled "Hereditary Breast Ovarian Cancer - HBOC: Optimizing hereditary cancer pathways (saving costs and lives)" lead by Carla Oliveira.
2020	2nd National Meeting of Young Oncology Researchers 2020 “Best Oral Communication” for the oral presentation entitled “Tumor immune profile reveals a new role for regulatory T cells in the development of gastric cancer” (to Sara Rocha; Carla Oliveira senio
2019	“ESHG National Fellowship 2019” for best presentation on “The role of CDH1 regulatory noncoding elements for E-cadherin expression” (to Celina S. José; Carla Oliveira senior author) Sociedade Portuguesa de Genética Humana: SPGH, Portugal
2019	“Mia Neri Award for the best talk in cancer research, Award 2019” for the oral presentation entitled “Structural variations at CDH1 intronic cis-regulatory elements cause CDH1/E-cadherin loss of function” (to Ana Rita Matos; Carla Oliveira senior author) European Society of Human Genetics, Áustria
2018	“ESHG National Fellowship 2018” for best oral presentation on “Intronic cis-regulatory elements regulate CDH1 gene expression and function” (to Ana Rita Matos; Carla Oliveira senior author) Sociedade Portuguesa de Genética Humana: SPGH, Portugal
2018	“Best Poster in Clinical Practice award” for the best clinical research work in Oncogenetics and Public Services in a Poster format, 2018 (to Luzia Garrido; Carla Oliveira senior author) European Society of Human Genetics, Áustria
2017	Prof. Doutor Amândio Tavares, FWA Award for the best basic research work in Oncogenetics and Public Services
2017	V Aeicbas Biomedical Congress / ICBAS "Best Poster Award" in PT, 2017 (to Celina São José; Carla Oliveira senior author) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017	“Prof. Doutor Amândio Tavares, FWA Award” for the best basic research work in Oncogenetics and Public Services in PT, 2017 (to Luzia Garrido; Carla Oliveira senior author) Sociedade Portuguesa de Genética Humana: SPGH, Portugal
2016	One of the 100 Portuguese female scientists featured in the Book “Mulheres na Ciência” CiênciaViva 2016.
2005	Best entry in the Winter submissions for EACR travel fellowships European Association For Cancer Research, Reino Unido
2004	SPGH Meeting “Young Investigator Award” for best basic research work in Human Genetics in PT 2004 (to Rachid Karam; Carla Oliveira senior author) Sociedade Portuguesa de Genética Humana, Portugal
2003	Labmed Prize for Research in health, 2003 (Carla Oliveira co-author) LabMED Saúde, Portugal
2003	Menção Honrosa da Sociedade Portuguesa de Genetica Humana Sociedade Portuguesa de Genética Humana, Portugal
2002	SPGH Meeting “Young Investigator Award” for best basic research work in Human Genetics in PT 2002 (to Carla Oliveira) Sociedade Portuguesa de Genética Humana, Portugal
2001	Labmed 2nd Prize for Research in health, 2001 (Carla Oliveira co-author) LabMED Saúde, Portugal
1998	Portuguese Rotary Club Portugal Prize for best Research work in Oncobiology in Portugal 1998 (to Carla Oliveira)