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Identificação

Identificação pessoal

Nome completo
David Pereira

Nomes de citação

  • Pereira, David

Identificadores de autor

Ciência ID
2918-F164-3036
ORCID iD
0000-0003-0384-7592
Formação
Grau Classificação
2023/07/19
Concluído
 David Pereira (Título de Agregado)
Universidade do Porto - Faculdade de Farmácia, Portugal
2014/08/31
Concluído
 Tissue Engineering & Regenerative Medicine (Pós-doutoramento)
Universidade do Minho, Portugal
2013/12/16
Concluído
 Ciências Farmacêuticas (Doutoramento)
Especialização em Fitoquímica e Farmacognosia
Universidade do Porto Faculdade de Farmácia, Portugal
2012
Concluído
 Gestão, Finanças e Marketing para Empreendedores (Pós-Graduação)
Universidade do Porto Porto Business School, Portugal
2009/09/01
Concluído
 Ciências Farmacêuticas (Mestrado integrado)
Universidade do Porto Faculdade de Farmácia, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/02/01 - 2014/08/31 Pós-doutorado (Investigação) Universidade do Minho, Portugal
Universidade do Minho, Portugal
2010/01/01 - 2013/12/31 Investigador (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2009/01/01 - 2009/12/31 Investigador (Investigação) Fundação para a Ciência e a Tecnologia, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/09/01 - Atual Professor Auxiliar (Docente Universitário) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
Projetos

Bolsa

Designação Financiadores
2023/02/01 - Atual Plasmonic dehydropeptide-based lipogels: functionalizing post-surgical patches against melanoma recurrence and metastases
2022.14573.BD
Orientador
Universidade do Porto Faculdade de Farmácia, Portugal
Em curso
2022/05/01 - Atual Augmenting the biological properties of alkylphenols by design and synthesis of novel phenol-alkaloid chimerics
Augmenting the biological properties of alkylphenols by design and synthesis of novel phenol-alkaloid chimerics
Orientador
Em curso
2020/09/01 - Atual Swainsonine Analogues Synthesis Assisted by Molecular Modeling. Biological Evaluation
n/a
Orientador
Universidade do Minho, Portugal

Sociedade Portuguesa de Química, Portugal
Sociedade Portuguesa de Química
Em curso
2018 - 2024/04/09 Scientific evidences on the use of plant species from Guinea-Bissau in ethnomedicine
SFRH/BD/144870/2019
Orientador
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Concluído
2017 - 2023/07 Endoplasmic reticulum stress in health and disease: new chemical tools for countering inflammation
SFRH/BD/130998/2017
Orientador
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Concluído
2018/07/26 - 2023/06 Biopesticides and Food Preservatives from Nanoencapsulated Plant Extracts Biological Evaluation, Molecular Modelling and Synthesis
PTDC/ASP-AGR/30154/2017
Investigador
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018 - 2022 Metabolomic profile and biological effects of endemic plant species from Thailand: towards evidence-based medicine
SFRH/BD/131431/2017
Orientador
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Concluído
2006/01/01 - 2006/12/31 Pieris brassicae como laboratório de síntese de novos compostos com potencial biológico a partir de Brassica oleracea var. costata, Brassica oleracea var. acephala e Brassica rapa var. rapa.
PTDC/AGR-AAM/64150/2006
Bolseiro de Iniciação Científica

Projeto

Designação Financiadores
2023/09 - Atual Goat farming systems characterization and novel strategies to sustain production in the changing climate scenario in the Mediterranean regions
PRIMA/0012/2022
Investigador
Universidade do Porto, Portugal
Em curso
2021/01 - Atual Marine Chemiluminescence as a Broad-Spectrum Anticancer Therapy with Enhanced Tumor-Selectivity and Activity
PTDC/QUI-QFI/2870/2020
 Fundação para a Ciência e a Tecnologia
Em curso
2020/11 - 2023/04/30 unCOVer - Unravelling Data for Rapid Evidence-Based Response to COVID-19
H2020-SC1-PHE-CORONAVIRUS-2020/101016216
Universidade do Porto Faculdade de Farmácia, Portugal
 European Commission
Em curso
2018/09/15 - 2023/04 Self-assembled minimalist peptide hydrogels inspired by mussel adhesive proteins for biomedical applications
PTDC/QUI-QOR/29015/2017
Investigador
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018/04/01 - 2023 Milk Quality along the Dairy Chain for a Safe and Sustainable MILK
PRIMA/0007/2018
Investigador responsável
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017 - 2021 IBERPHENOL – Cooperative network on polyphenols research and their industrial applications
IBERPHENOL
Investigador
Universidade do Porto Faculdade de Farmácia, Portugal
 Interreg Europe
Em curso
2016 - 2019 New Technologies for three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases
DESIGNBiotecHealth
Investigador
REQUIMTE, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 6 - 2011-2012
PEst-C/EQB/LA0006/2011
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2009/01/01 - 2009/12/31 Pieris brassicae como laboratório de síntese de novos compostos com potencial biológico a partir de Brassica oleracea var. costata, Brassica oleracea var. acephala e Brassica rapa var. rapa.
PTDC/AGR-AAM/64150/2006
Bolseiro de Investigação
Concluído
Produções

Publicações

Artigo em conferência
  1. Ribeiro, MAF; Vieira, TF; Fernandes, MJG; Pereira, RB; Pereira, DM; Castanheira, EMS; Fortes, AG; Sousa, SF; Gonçalves, MST. "Synthesis and In Silico Evaluation of Potential Insecticide Activity of Benzamides". 2021.
    10.3390/ecsoc-25-11770
Artigo em revista
  1. Sara C. Silva-Reis; Costa, Vera Marisa; da Silva, Daniela Correia; Pereira, David; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; García-Mera, Xerardo; J. E. Rodriguez-Borges; Ivo E. Sampaio-Dias. Autor correspondente: Ivo E. Sampaio-Dias. "Exploring Structural Determinants of Neuroprotection Bias on Novel Glypromate Conjugates with Bioactive Amines". European Journal of Medicinal Chemistry (2024):
    Aceite para publicação
  2. Vera Ribeiro; Federico Ferreres; Andreia Oliveira; Gomes, N.M.; Angel Gil-Izquierdo; Luísa Araújo; David Pereira; Patrícia Valentão. "Allophylus africanus Stem Bark Extract Modulates the Mitochondrial Apoptotic Pathway in Human Stomach Cancer Cells". Life (2023): https://www.mdpi.com/2075-1729/13/2/406.
    10.3390/life13020406
  3. Lucía Bada Díaz; Renato Pereira; David Pereira; Marta Lores; Maria Celeiro; Elías Quezada; Eugenio Uriarte; José Gil-Longo; Dolores Viña. "Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)". Molecules (2023): https://www.mdpi.com/1420-3049/28/1/351.
    10.3390/molecules28010351
  4. Morteza Hosseini; David Pereira. "The Chemical Space of Terpenes: Insights from Data Science and AI". Pharmaceuticals (2023): https://www.mdpi.com/1424-8247/16/2/202.
    10.3390/ph16020202
  5. Andrade, C.; Pereira, D.M.; G. M. Gomes, N.; Ferreres, F.; Gil-Izquierdo, A.; Andrade, P.B.; Duangsrisai, S.; Valentão, P.. "Kitul, a food plant with antidiabetic-like effects: Reduction of intracellular reactive species in glucose-stimulated RIN-5F pancreatic ß-cells and mitigation of pro-inflammatory mediators in activated RAW 264.7 macrophages". Food Research International 167 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85149174409&partnerID=MN8TOARS.
    10.1016/j.foodres.2023.112615
  6. Correia da Silva, D.; Jervis, P.J.; Martins, J.A.; Valentão, P.; Ferreira, P.M.T.; Pereira, D.M.. "Fisetin derivatives exhibit enhanced anti-inflammatory activity and modulation of endoplasmic reticulum stress". International Immunopharmacology 119 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85152398322&partnerID=MN8TOARS.
    10.1016/j.intimp.2023.110178
  7. Boulebd, H.; Pereira, D.M.. "Examination of the Antioxidant Activity of Psoralidin: Computational Mechanistic Study and Impact on the ROS Level in Human Keratinocytes". Journal of Organic Chemistry 88 9 (2023): 5745-5751. http://www.scopus.com/inward/record.url?eid=2-s2.0-85154053136&partnerID=MN8TOARS.
    10.1021/acs.joc.3c00193
  8. Magalhaes, C.M.; Ducic, T.; Pereira, R.B.; González-Berdullas, P.; Rodríguez-Borges, J.E.; Pereira, D.M.; Esteves da Silva, J.C.G.; Algarra, M.; Pinto da Silva, L.. "Synchrotron-based FTIR evaluation of biochemical changes in cancer and noncancer cells induced by brominated marine coelenteramine". Archives of Biochemistry and Biophysics 743 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85160782362&partnerID=MN8TOARS.
    10.1016/j.abb.2023.109660
  9. Pereira, R.B.; Rahali, F.Z.; Nehme, R.; Falleh, H.; Jemaa, M.B.; Sellami, I.H.; Ksouri, R.; et al. "Anti-inflammatory activity of essential oils from Tunisian aromatic and medicinal plants and their major constituents in THP-1 macrophages". Food Research International 167 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85150226788&partnerID=MN8TOARS.
    10.1016/j.foodres.2023.112678
  10. Macedo, T.; Paiva-Martins, F.; Ferreres, F.; Gomes, N.G.M.; Oliveira, A.P.; Gil-Izquierdo, Á.; Araújo, L.; Valentão, P.; Pereira, D.M.. "Anti-inflammatory effects of naringenin 8-sulphonate from Parinari excelsa Sabine stem bark and its semi-synthetic derivatives". Bioorganic Chemistry 138 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85162253026&partnerID=MN8TOARS.
    10.1016/j.bioorg.2023.106614
  11. Vitale, I.; Pietrocola, F.; Guilbaud, E.; Aaronson, S.A.; Abrams, J.M.; Adam, D.; Agostini, M.; et al. "Apoptotic cell death in disease—Current understanding of the NCCD 2023". Cell Death and Differentiation 30 5 (2023): 1097-1154. http://www.scopus.com/inward/record.url?eid=2-s2.0-85153609153&partnerID=MN8TOARS.
    10.1038/s41418-023-01153-w
  12. Wu, D.; Jin, Y.; Xing, Y.; Abate, M.D.; Abbasian, M.; Abbasi-Kangevari, M.; Abbasi-Kangevari, Z.; et al. "Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019". eClinicalMedicine 64 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85172929794&partnerID=MN8TOARS.
    10.1016/j.eclinm.2023.102193
  13. Rechek, H.; Haouat, A.; Hamaidia, K.; Pinto, D.C.G.A.; Boudiar, T.; Válega, M.S.G.A.; Pereira, D.M.; Pereira, R.B.; Silva, A.M.S.. "Inula viscosa (L.) Aiton Ethanolic Extract Inhibits the Growth of Human AGS and A549 Cancer Cell Lines". Chemistry and Biodiversity 20 3 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85147940850&partnerID=MN8TOARS.
    10.1002/cbdv.202200890
  14. Ranilla, M.J.; Andrés, S.; Gini, C.; Biscarini, F.; Saro, C.; Martín, A.; Mateos, I.; et al. "Effects of Thymbra capitata essential oil on in vitro fermentation end-products and ruminal bacterial communities". Scientific Reports 13 1 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85150090527&partnerID=MN8TOARS.
    10.1038/s41598-023-31370-9
  15. Olim, P.; Pereira, R.B.; Fernandes, M.J.G.; Natal, C.M.; Coelho, J.R.A.; Fortes, A.G.; Gonçalves, M.S.T.; Pereira, D.M.. "Structural modification of naturally occurring phenolics as a strategy for developing cytotoxic molecules towards cancer cells". Archiv der Pharmazie 356 12 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85173717708&partnerID=MN8TOARS.
    10.1002/ardp.202300294
  16. Daniela Correia da Silva; Patrícia Valentão; David Pereira. "A Survey of Naturally Occurring Molecules as New Endoplasmic Reticulum Stress Activators with Selective Anticancer Activity". Cancers (2022): https://www.mdpi.com/2072-6694/15/1/293.
    10.3390/cancers15010293
  17. Mariem Ben Jemaa; Fatma Zohra Rahali; Hanen Falleh; Raja Beji-Serairi; Wided Megdiche-Ksouri; Ibtissem Hamrouni; Majdi Hammami; et al. "Essential Oil Stabilisation by Response Surface Methodology (RSM): Nanoemulsion Formulation, Physicochemical, Microbiological, and Sensory Investigations". Molecules (2022): https://www.mdpi.com/1420-3049/27/21/7330.
    10.3390/molecules27217330
  18. Carlos Oliveira; Renato Pereira; David Pereira; loic hilliou; Tarsila G. Castro; J.A. Martins; Peter J. Jervis; Paula MT Ferreira. "Aryl-Capped Lysine-Dehydroamino Acid Dipeptide Supergelators as Potential Drug Release Systems". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/19/11811.
    10.3390/ijms231911811
  19. Maria José G. Fernandes; Renato Pereira; Rita Rodrigues; Tatiana F. Vieira; A. Gil Fortes; David Pereira; Sergio F. Sousa; M Sameiro T Gonçalves; Elisabete M. S. Castanheira. "Liposomal Formulations Loaded with a Eugenol Derivative for Application as Insecticides: Encapsulation Studies and In Silico Identification of Protein Targets". Nanomaterials (2022): https://www.mdpi.com/2079-4991/12/20/3583.
    10.3390/nano12203583
  20. Patricia González-Berdullas; Renato Pereira; Cláudia Teixeira; José Pedro Silva; Carla Magalhães; José E. Rodríguez-Borges; David Pereira; Joaquim C.G. Esteves da Silva; Luís Pinto da Silva. "Discovery of the Anticancer Activity for Lung and Gastric Cancer of a Brominated Coelenteramine Analog". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/15/8271.
    10.3390/ijms23158271
  21. "HPLC-DAD-ESI/MSn and UHPLC-ESI/QTOF/MSn characterization of polyphenols in the leaves of Neocarya macrophylla (Sabine) Prance ex F. White and cytotoxicity to gastric carcinoma cells". Food Research International 155 (2022): 111082-111082. http://dx.doi.org/10.1016/j.foodres.2022.111082.
    10.1016/j.foodres.2022.111082
  22. "Eugenol ß-Amino/ß-Alkoxy Alcohols with Selective Anticancer Activity". International Journal of Molecular Sciences 23 7 (2022): 3759-3759. http://dx.doi.org/10.3390/ijms23073759.
    10.3390/ijms23073759
  23. Ajoolabady, Amir; Liu, Simin; Klionsky, Daniel J.; Lip, Gregory Y.H.; Tuomilehto, Jaakko; Kavalakatt, Sina; Pereira, David M.; Samali, Afshin; Ren, Jun. "ER stress in obesity pathogenesis and management". Trends in Pharmacological Sciences 43 2 (2022): 97-109. http://dx.doi.org/10.1016/j.tips.2021.11.011.
    10.1016/j.tips.2021.11.011
  24. Boulebd, Houssem; Pereira, David M.; Amine Khodja, Imene; Hoa, Nguyen Thi; Mechler, Adam; Vo, Quan V.. "Assessment of the free radical scavenging potential of cannabidiol under physiological conditions: Theoretical and experimental investigations". Journal of Molecular Liquids 346 (2022): 118277. http://dx.doi.org/10.1016/j.molliq.2021.118277.
    10.1016/j.molliq.2021.118277
  25. Coelho, CMM; Pereira, RB; Vieira, TF; Teixeira, CM; Fernandes, MJG; Rodrigues, ARO; Pereira, DM; et al. "Synthesis, computational and nanoencapsulation studies on eugenol-derived insecticides". NEW JOURNAL OF CHEMISTRY (2022):
    10.1039/d2nj01893d
  26. Veloso, SRS; Gomes, V; Mendes, SLF; Hilliou, L; Pereira, RB; Pereira, DM; Coutinho, PJG; et al. "Plasmonic lipogels: driving co-assembly of composites with peptide-based gels for controlled drug release". SOFT MATTER (2022):
    10.1039/d2sm00926a
  27. Oliveira, CBP; Veloso, SRS; Castanheira, EMS; Figueiredo, PR; Carvalho, ATP; Hilliou, L; Pereira, RB; et al. "An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration-prepared from a known folate receptor ligand". SOFT MATTER (2022):
    10.1039/d2sm00121g
  28. Andrade, C; Ferreres, F; Gomes, NGM; Gil Izquierdo, A; Duangsrisai, S; Pereira, DM; Andrade, PB; Valentao, P. "Valorisation of the industrial waste of Chukrasia tabularis A.Juss.: Characterization of the leaves phenolic constituents and antidiabetic-like effects". INDUSTRIAL CROPS AND PRODUCTS (2022):
    10.1016/j.indcrop.2022.115100
  29. da Silva, DC; Valentao, P; Andrade, PB; Pereira, DM. "A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress". FRONTIERS IN PHARMACOLOGY (2022):
    10.3389/fphar.2022.956154
  30. Fathi, F; Ebrahimi, SN; Pereira, DM; Estevinho, BN; Rocha, F. "Preliminary studies of microencapsulation and anticancer activity of polyphenols extract from Punica granatum peels". CANADIAN JOURNAL OF CHEMICAL ENGINEERING (2022):
    10.1002/cjce.24348
  31. Iburg, KM; Charalampous, P; Allebeck, P; Stenberg, EJ; O'Caoimh, R; Monasta, L; Penalvo, JL; et al. "Burden of disease among older adults in Europe-trends in mortality and disability, 1990-2019". EUROPEAN JOURNAL OF PUBLIC HEALTH (2022):
    10.1093/eurpub/ckac160
  32. Fathi, F.; Ebrahimi, S.N.; Pereira, D.M.; Estevinho, B.N.; Rocha, F.. "Microencapsulation of Enriched Extracts of Two Satureja Species by Spray Drying, Evaluation of the Controlled Release Mechanism and Cytotoxicity". Pharmaceutical Sciences 28 1 (2022): 145-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-85127181104&partnerID=MN8TOARS.
    10.34172/PS.2021.54
  33. "Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019". JAMA Oncology (2021): http://dx.doi.org/10.1001/jamaoncol.2021.6987.
    10.1001/jamaoncol.2021.6987
  34. Renato Pereira; Nuno F. S. Pinto; Maria José G. Fernandes; Tatiana F. Vieira; Rita Rodrigues; David Pereira; Sérgio F. Sousa; et al. "Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights". Molecules (2021): https://www.mdpi.com/1420-3049/26/21/6616.
    10.3390/molecules26216616
  35. Carolina Amorim; Sérgio Veloso; E. M. S. Castanheira; loic hilliou; Renato Pereira; David Pereira; J.A. Martins; Peter J. Jervis; Paula MT Ferreira. "Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems". Gels (2021): https://www.mdpi.com/2310-2861/7/2/52.
    10.3390/gels7020052
  36. Peter J. Jervis; loic hilliou; Renato Pereira; David Pereira; J.A. Martins; Paula MT Ferreira. "Evaluation of a Model Photo-Caged Dehydropeptide as a Stimuli-Responsive Supramolecular Hydrogel". Nanomaterials (2021): https://www.mdpi.com/2079-4991/11/3/704.
    10.3390/nano11030704
  37. Ralph Nehme; Sonia Andrés; Renato Pereira; Meriem Ben Jemaa; Saïd Bouhallab; Fabrizio Ceciliani; Secundino Lopez; et al. "Essential Oils in Livestock: From Health to Food Quality". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/2/330.
    10.3390/antiox10020330
  38. Ribeiro, V; Ferreres, F; Macedo, T; Gil Izquierdo, Á; Oliveira, AP; Gomes, NGM; Araújo, L; et al. "Activation of caspase-3 in gastric adenocarcinoma AGS cells by Xylopia aethiopica (Dunal) A. Rich. fruit and characterization of its phenolic fingerprint by HPLC-DAD-ESI(Ion Trap)-MSn and UPLC-ESI-QTOF-MS2". Food Research International (2021):
    10.1016/j.foodres.2021.110121
  39. Joao, KG; Videira, RA; Paiva Martins, F; Valentao, P; Pereira, DM; Andrade, PB. "Homarine Alkyl Ester Derivatives as Promising Acetylcholinesterase Inhibitors". CHEMMEDCHEM (2021):
    10.1002/cmdc.202100265
  40. Pereira, DGM; Vieira, JM; Vicente, AA; Cruz, RMS. "Development and Characterization of Pectin Films with Salicornia ramosissima: Biodegradation in Soil and Seawater". POLYMERS (2021):
    10.3390/polym13162632
  41. Natal, CM; Fernandes, MJG; Pinto, NFS; Pereira, RB; Vieira, TF; Rodrigues, ARO; Pereira, DM; et al. "New carvacrol and thymol derivatives as potential insecticides: synthesis, biological activity, computational studies and nanoencapsulation". RSC ADVANCES (2021):
    10.1039/d1ra05616f
  42. Macedo, T; Ferreres, F; Pereira, DM; Oliveira, AP; Gomes, NGM; Gil Izquierdo, A; Valentao, P; Araujo, L; Andrade, PB. "Cassia sieberiana DC. leaves modulate LPS-induced inflammatory response in THP-1 cells and inhibit eicosanoid-metabolizing enzymes". JOURNAL OF ETHNOPHARMACOLOGY (2021):
    10.1016/j.jep.2020.113746
  43. Veloso, SRS; Jervis, PJ; Silva, JFG; Hilliou, L; Moura, C; Pereira, DM; Coutinho, PJG; et al. "Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery". MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021):
    10.1016/j.msec.2021.111869
  44. Peñalvo, J.L.; Mertens, E.; Ademovic, E.; Akgun, S.; Baltazar, A.L.; Buonfrate, D.; G Oklo, M.; et al. "Unravelling data for rapid evidence-based response to COVID-19: A summary of the unCoVer protocol". BMJ Open 11 11 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85120371425&partnerID=MN8TOARS.
    10.1136/bmjopen-2021-055630
  45. Johnson, S.C.; Cunningham, M.; Dippenaar, I.N.; Sharara, F.; Wool, E.E.; Agesa, K.M.; Han, C.; et al. "Public health utility of cause of death data: applying empirical algorithms to improve data quality". BMC Medical Informatics and Decision Making 21 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85107196002&partnerID=MN8TOARS.
    10.1186/s12911-021-01501-1
  46. Pech-Puch, D.; Joseph-Nathan, P.; Burgueño-Tapia, E.; González-Salas, C.; Martínez-Matamoros, D.; Pereira, D.M.; Pereira, R.B.; Jiménez, C.; Rodríguez, J.. "Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum". Scientific Reports 11 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85099231696&partnerID=MN8TOARS.
    10.1038/s41598-020-79774-1
  47. Maria José G. Fernandes; Renato Pereira; David Pereira; António Gil Fortes; E. M. S. Castanheira; M Sameiro T Gonçalves. "New Eugenol Derivatives with Enhanced Insecticidal Activity". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/21/23/9257.
    10.3390/ijms21239257
  48. Ana I. F. Lopes; Mariana Monteiro; Ana Araújo; Rita Rodrigues; E. M. S. Castanheira; David Pereira; Pedro Olim; António Gil Fortes; M Sameiro T Gonçalves. "Cytotoxic Plant Extracts towards Insect Cells: Bioactivity and Nanoencapsulation Studies for Application as Biopesticides". Molecules (2020): https://www.mdpi.com/1420-3049/25/24/5855.
    10.3390/molecules25245855
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  160. Pereira, D.M.; Ferreres, F.; Oliveira, J.M.A.; Gaspar, L.; Faria, J.; Valentão, P.; Sottomayor, M.; Andrade, P.B.. "Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission". Phytomedicine 17 8-9 (2010): 646-652. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952289058&partnerID=MN8TOARS.
    10.1016/j.phymed.2009.10.008
  161. Fernandes, F.; Pereira, D.M.; Guedes de Pinho, P.; Valentão, P.; Pereira, J.A.; Bento, A.; Andrade, P.B.. "Headspace solid-phase microextraction and gas chromatography/ion trap-mass spectrometry applied to a living system: Pieris brassicae fed with kale". Food Chemistry 119 4 (2010): 1681-1693. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449622753&partnerID=MN8TOARS.
    10.1016/j.foodchem.2009.09.046
  162. Ferreres, F.; Pereira, D.M.; Gil-Izquierdo, A.; Valentão, P.; Botelho, J.; Mouga, T.; Andrade, P.B.. "HPLC-PAD-atmospheric pressure chemical ionization-MS metabolite profiling of cytotoxic carotenoids from the echinoderm Marthasterias glacialis (spiny sea-star)". Journal of Separation Science 33 15 (2010): 2250-2257. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955345220&partnerID=MN8TOARS.
    10.1002/jssc.201000197
  163. Federico Ferreres; Carla Sousa; David M. Pereira; Patrícia Valentão; Marcos Taveira; Anabela Martins; José A. Pereira; Rosa M. Seabra; Andrade, P.B.. "Screening of antioxidant phenolic compounds produced by in Vvitro shoots of brassica oleracea L. var. costata DC". Combinatorial Chemistry and High Throughput Screening 12 3 (2009): 230-240. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549148984&partnerID=MN8TOARS.
    10.2174/138620709787581756
  164. Taveira, M.; Pereira, D.M.; Sousa, C.; Ferreres, F.; Andrade, P.B.; Martins, A.; Pereira, J.A.; Valentão, P.. "In vitro cultures of Brassica oleracea L. var. costata DC: Potential plant bioreactor for antioxidant phenolic compounds". Journal of Agricultural and Food Chemistry 57 4 (2009): 1247-1252. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549084111&partnerID=MN8TOARS.
    10.1021/jf803496x
  165. Pereira, D.M.; Faria, J.; Gaspar, L.; Valentão, P.; Andrade, P.B.. "Boerhaavia diffusa: Metabolite profiling of a medicinal plant from Nyctaginaceae". Food and Chemical Toxicology 47 8 (2009): 2142-2149. http://www.scopus.com/inward/record.url?eid=2-s2.0-68649108100&partnerID=MN8TOARS.
    10.1016/j.fct.2009.05.033
  166. Sousa, C.; Pereira, D.M.; Taveira, M.; Dopico-García, S.; Valentão, P.; Pereira, J.A.; Bento, A.; Andrade, P.B.. "Brassica oleracea var. costata: comparative study on organic acids and biomass production with other cabbage varieties". Journal of the Science of Food and Agriculture 89 6 (2009): 1083-1089. http://www.scopus.com/inward/record.url?eid=2-s2.0-63849281441&partnerID=MN8TOARS.
    10.1002/jsfa.3559
  167. Pereira, David. "Phenolics Metabolism in Insects:Pieris brassicae-Brassica oleraceavar.costataEcological Duo". (2009):
    10.1021/jf901538j
  168. Pereira, David. "Phenolics: From Chemistry to Biology". (2009):
    10.3390/molecules14062202
  169. Pereira, David. "Metabolic fate of dietary volatile compounds in Pieris brassicae". (2009):
    10.1016/j.microc.2009.05.006
  170. Pereira, D.M.; Ferreres, F.; Oliveira, J.; Valentão, P.; Andrade, P.B.; Sottomayor, M.. "Targeted metabolite analysis of Catharanthus roseus and its biological potential". Food and Chemical Toxicology 47 6 (2009): 1349-1354. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349155921&partnerID=MN8TOARS.
    10.1016/j.fct.2009.03.012
  171. Guedes De Pinho, P.; Gonçalves, R.F.; Valentão, P.; Pereira, D.M.; Seabra, R.M.; Andrade, P.B.; Sottomayor, M.. "Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry". Journal of Pharmaceutical and Biomedical Analysis 49 3 (2009): 674-685. http://www.scopus.com/inward/record.url?eid=2-s2.0-61449166897&partnerID=MN8TOARS.
    10.1016/j.jpba.2008.12.032
  172. Pereira, D.M.; Norms, A.; Valentao, P.; Ferreres, F.; Pereira, J.A.; Vale-Silva, L.; Pinto, E.; Andrade, P.B.. "Targeted metabolite analysis and biological activity of Pieris brassicae fed with brassica rapa var. rapa". Journal of Agricultural and Food Chemistry 57 2 (2009): 483-489. http://www.scopus.com/inward/record.url?eid=2-s2.0-59849096009&partnerID=MN8TOARS.
    10.1021/jf8031638
  173. Sousa, C.; Pereira, D.M.; Valentão, P.; Ferreres, F.; Pereira, J.A.; Seabra, R.M.; Andrade, P.B.. "Pieris brassicae inhibits xanthine oxidase". Journal of Agricultural and Food Chemistry 57 6 (2009): 2288-2294. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549114951&partnerID=MN8TOARS.
    10.1021/jf803831v
  174. Sousa, C.; Pereira, D.M.; Pereira, J.A.; Bento, A.; Rodrigues, M.A.; Dopico-García, S.; Valentão, P.; et al. "Multivariate analysis of tronchuda cabbage (Brassica oleracea L. var. costata DC) phenolics: Influence of fertilizers". Journal of Agricultural and Food Chemistry 56 6 (2008): 2231-2239. http://www.scopus.com/inward/record.url?eid=2-s2.0-41849090797&partnerID=MN8TOARS.
    10.1021/jf073041o
  175. Ferreres, F.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Seabra, R.M.; Sottomayor, M.. "New phenolic compounds and antioxidant potential of Catharanthus roseus". Journal of Agricultural and Food Chemistry 56 21 (2008): 9967-9974. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149328810&partnerID=MN8TOARS.
    10.1021/jf8022723
  176. Oliveira, A.P.; Pereira, D.M.; Andrade, P.B.; Valentão, P.; Sousa, C.; Pereira, J.A.; Bento, A.; et al. "Free amino acids of tronchuda cabbage (Brassica oleracea L. Var. costata DC): Influence of leaf position (internal or external) and collection time". Journal of Agricultural and Food Chemistry 56 13 (2008): 5216-5221. http://www.scopus.com/inward/record.url?eid=2-s2.0-47849120635&partnerID=MN8TOARS.
    10.1021/jf800563w
  177. Andrade, P.B.; Pereira, D.M.; Ferreres, F.; Valentao, P.. "Recent trends in high throughput analysis and antioxidant potential screening for phenolics". Current Pharmaceutical Analysis 4 3 (2008): 137-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-53749084805&partnerID=MN8TOARS.
    10.2174/157341208785161263
  178. Silva, Branca M.; Oliveira, Andreia; Pereira, David; Sousa, Carla; Seabra, Rosa; Andrade, Paula. "Tronchuda cabbage (Brassica oleraceae L. var. costata DC) leaf free amino acid profile". Planta Medica 9 74 (2008): 1092-1092.
    Publicado
  179. Sousa, C.; Lopes, G.; Pereira, D.M.; Taveira, M.; Valentão, P.; Seabra, R.M.; Pereira, J.A.; et al. "Screening of antioxidant compounds during sprouting of Brassica oleracea L. var. costata DC". Combinatorial Chemistry and High Throughput Screening 10 5 (2007): 377-386. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548453591&partnerID=MN8TOARS.
    10.2174/138620707781662817
Capítulo de livro
  1. Pereira, D.M.; Fernandes, J.C.. "The power of genomics, metabolomics, and other omics for target identification and validation". 33-48. 2021.
  2. Pereira, D.M.; da-Silva, G.C.; Valentão, P.; Teixeira, N.; Andrade, P.B.. "Marine metabolomics in cancer chemotherapy". 379-400. 2016.
  3. Pereira, D.M.; Valentão, P.; Andrade, P.B.. "Meroterpenes from marine invertebrates: Chemistry and application in cancer". 2015.
    10.1007/978-3-319-07145-9_21
  4. Pereira, D.M.; Fernandes, J.C.; Valent¿o, P.; Andrade, P.B.. "Target Identification and Validation: "Omics" Technologies: Promises and Benefits for Molecular Medicine". 2015.
    10.1016/B978-0-12-800687-0.00003-7
  5. Pereira, DM; Andrade, PB; Pires, RA; Reis, RL. "Chemical ecology of echinoderms: Impact of environment and diet in metabolomic profile". 2014.
  6. Pereira, DM. "Naturally-derived molecules as a strategy for countering E. faecalis infection". 2014.
  7. Pereira, D.M.; Valentão, P.; Andrade, P.B.. "Lessons from the sea: Distribution, sar, and molecular mechanisms of anti-inflammatory drugs from marine organisms". 2013.
    10.1016/B978-0-444-59603-1.00007-2
  8. Pereira, DM; Valentão, P; Sottomayor, M; Ferreres, F; Andrade, PB. "Phenolic compounds in Catharanthus roseus". 2013.
    10.1007/978-3-642-22144-6_96
  9. Pereira, D.M.; Valentão, P.; Ferreres, F.; Sottomayor, M.; Andrade, P.B.. "Rediscovering catharanthus roseus: Chemistry and biological activity". 2012.
  10. Pereira, D.M.; Ferreres, F.; Valentão, P.-A.; Andrade, P.B.. "Brassica Seeds: Metabolomics and Biological Potential". In Pharmaceutics. 2011.
    10.1016/B978-0-12-375688-6.10009-X
  11. Pereira, D.M.; Valentão, P.; Ferreres, F.; Andrade, P.B.. "Metabolomic analysis of natural products". 2010.
    10.2174/978160805190811001010001
  12. Valentão, P.; Guerra, L.; Pereira, D.M.; Andrade, P.B.. "Red wine phenolics: Reasons for their variation". 2009.
  13. Andrade, P.B.; Valentão, P.; Sousa, C.; Pereira, D.M.; Taveira, M.; Seabra, R.M.; Ferreres, F.; Silva, B.M.. "Recent advances in Brassica oleracea and Brassica rapa varieties phenolics". In Pharmaceutics. 2008.
Poster em conferência
  1. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; da Silva, Daniela Correia; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera Marisa; et al. "Discovery of Glypromate Conjugates with Biomedical Applications in Alzheimer's Disease". Trabalho apresentado em 2nd Symposium on Alzheimer's Disease, 2023.
  2. Sara C. Silva-Reis; Ivo E. Sampaio-Dias; da Silva, Daniela Correia; Correia, Xavier Cruz; Costa-Almeida, Hugo F.; Beatriz L. Pires-Lima; Costa, Vera Marisa; et al. "Discovery of Glypromate Conjugates with Biomedical Applications in Alzheimeir's Disease". Trabalho apresentado em 2nd Symposium on Alzheimer's Disease, 2023.
  3. Rocha, Lídia; Valentão, Patrícia; Pereira, David; Andrade, Paula; Videira, Romeu. "Exploring the bioactivity of white wine phenolics in the context of type II diabetes and Alzheimer disease interlink". Trabalho apresentado em IJUP'18, 2018.
Resumo em conferência
  1. Pereira, D; Correia da Silva, G; Valentao, P; Teixeira, N; Andrade, PB. "Modulation of Cox-2 and iNOS expression in macrophages by a lipophylic extract of the sea-star Marthasterias glacialis: cooperative effect of fatty acids and ergosta-7,22-dien-3-ol". 2013.
  2. Pereira, D; Correia da Silva, G; Valentao, P; Teixeira, N; Andrade, PB. "Biological properties of a lipophilic extract of sea-star Marthasterias glacialis L. upon several cancer cell lines". 2012.
  3. Oliveira, Andreia; Silva, Luís; Taveira, M.; Pereira, David; Guedes de Pinho, Paula; Valentão, Patrícia; Silva, Branca M.; Pereira, José; Andrade, Paula. "Determination of volatile compounds in Portuguese Ficus carica L. varieties by HS-SPME and GC/MS". Trabalho apresentado em 6º Encontro Nacional de Cromatografia, Funchal, 2009.
    Publicado
  4. Pereira, DM; Noites, A; Valentao, P; Vale Silva, L; Pinto, E; Ferreres, F; Pereira, JA; Seabra, RM; Andrade, PB. "Phenolics and organic acids with potential bioactivity in Pieris brassicae L. reared on Brassica rapa var. rapa L". 2008.
  5. Silva, BM; Oliveira, AP; Pereira, DM; Sousa, C; Seabra, RM; Andrade, PB. "Tronchuda cabbage (Brassica oleracea L. var. costata DC) leaf free amino acid profile". 2008.
  6. Valentao, P; Ferreres, F; Sousa, C; Pereira, DM; Martins, A; Gomes, D; Pereira, JA; et al. "Screening of antioxidant phenolic compounds produced by in vitro shoots of Brassica oleracea L. var. costata DC". 2008.
  7. de Pinho, PG; Goncalves, R; Pereira, DM; Valentao, P; Seabra, RM; Andrade, PB; Sottomayor, M. "Volatile profile of Catharanthus roseus (L.) G. Don plant determined by solid-phase microextraction and gas-chromatography/mass-spectrometry". 2008.

Outros

Outra produção
  1. Exploring Structural Determinants of Neuroprotection Bias on Novel Glypromate Bioconjugates with Bioactive Amines. 2023. Silva-Reis, S.C.; Costa, V.M.; da Silva, D.C.; Pereira, D.M.; Correia, X.C.; Costa-Almeida, H.F.; García-Mera, X.; Rodríguez-Borges, J.E.; Sampaio-Dias, I.E.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85174872403&partnerID=MN8TOARS.
    10.2139/ssrn.4601854
  2. A pipeline for natural small molecule inhibitors of endoplasmic reticulum stress. 2022. Da Silva, D.C.; Valentão, P.; Andrade, P.B.; Pereira, D.M.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85126864048&partnerID=MN8TOARS.
    10.1101/2022.02.20.481203
  3. A survey of naturally-occurring molecules as new endoplasmic reticulum stress activators with selective anticancer activity. 2022. da Silva, D.C.; Valentão, P.; Pereira, D.M.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85143659266&partnerID=MN8TOARS.
    10.1101/2022.10.16.512420
  4. Bolaamphiphilic Bis-dehydropeptide hydrogels as potential drug release systems. 2021. Amorim, C.; Veloso, S.R.S.; Castanheira, E.M.S.; Hilliou, L.; Pereira, R.B.; Pereira, D.M.; Martins, J.A.; Jervis, P.J.; Ferreira, P.M.T.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105276702&partnerID=MN8TOARS.
    10.26434/chemrxiv.14261903
  5. The Era of -Omics. 2012. Pereira, DM. https://www.authenticus.pt/P-002-BPM.
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023 - Atual Dehydropeptide based self-assembled injectable hydrogels for cardiac delivery
Coorientador
2022 - Atual Augmenting the biological properties of alkylphenols by design and synthesis of novel phenol-alkaloid chimerics.
Coorientador
2022 - Atual Plasmonic dehydropeptide-based lipogels: functionalizing post-surgical patches against melanoma recurrence and metastases.
Coorientador
2019 - Atual Swainsonine analogues synthesis assisted by molecular modeling and biological evaluation.
Coorientador
2018 - 2024/04/09 Anti-inflammatory properties of plant species from Guinea-Bissau: A contribute to ethnopharmacology
Orientador
2021/09/01 - 2023 Chemistry and pharmacotechnics of natural hydrogels
Orientador
2018 - 2023 Endoplasmic reticulum stress in health and disease: new chemical tools for countering inflammation.
Orientador
2018 - 2022 Práticas etnofarmacológicas na Guiné-Bissau: Estudo fitoquímico e biológico de espécies com atividade citotóxica em células de cancro.
Coorientador
2018 - 2022 Valorization of species from Thailand flora: Phenolic characterization and antidiabetic properties.
Coorientador
2019/10/01 - 2021/12/21 Cytotoxicity studies of phytochemicals and/or synthetic natural derivatives
Orientador
 Master in Applied Biochemistry (Mestrado)
Universidade do Minho Escola de Ciências, Portugal
2019/10/01 - 2021/07/28 Food preservatives based in natural bioactive molecules
Coorientador
 Master in Applied Biochemsitry (Mestrado)
Universidade do Minho Escola de Ciências, Portugal
2018/09/01 - 2020/09/24 Discovery and characterization of natural insecticides in insect cells
Orientador
 Master in Analytical, Clinical and Forensic Toxicology (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/09/01 - 2018/07/31 Quality Control of Honey: Research and Evaluation of Pyrrolizidine Alkaloids and Phenolic Compounds
Coorientador
 Master in Quality Control (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09/01 - 2017/07/25 Assessment of molecules of natural origin and their derivatives in protein degradation mechanisms
Orientador
 Master in Quality Control (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/09/01 - 2016/07/26 Toxicity of glycoalkaloids from lycopersicon esculentum mill. - a mechanistic perspective
Coorientador
 Master in Analytical, Clinical and Forensic Toxicology (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/09/01 - 2016/06/29 Sea anemones: new biological perspectives
Orientador
 Master in Quality Control (Mestrado)
Universidade do Porto Faculdade de Farmácia, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2018/05/10 Multimodal actions of brown seaweed (Ochrophyta) bioactive compounds in inflammation and allergy network
Vogal
 Mariana Nunes Barbosa (Doutoramento)
Universidade do Porto, Portugal
2016/03/02 Effects of Echium plantagineum L. bee pollen on macrophages and basophils: metabolic profile vs inflammatory mediators, degranulation and oxidative stress
Vogal
 Maria Eduarda da Rocha Pereira Dias Moita (Doutoramento)
Universidade do Porto, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2018 - Atual Evaluation Panel, EEA Grants
Membro
 Executive Agency for Higher Education, Research, Development and Innovation Funding, Roménia
2017 - Atual ERA.NET Expert
Membro