Identificação pessoal

Nome completo
Ana Eulalio

Nomes de citação

  • Eulalio, Ana

Identificadores de autor

Ciência ID
Researcher Id
Scopus Author Id


  • Center for Neuroscience and Cell Biology (CNC), University of Coimbra. UC-BIOTECH, Parque Tecnologico de Cantanhede, Nucleo 04, Lote 08, 3060-197, Cantanhede, Cantanhede, Portugal (Profissional)
  • Imperial College London, South Kensington Campus, Armstrong Road, Flowers building, room 1.42, SW7 2AZ, London, London, Reino Unido (Profissional)


Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Microbiologia
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular


Artigo em revista
  1. Rodrigues Lopes, Inês; Laura Maria Alcantara; Ricardo Silva; Jérôme JOSSE; Elena Pedrero Vega; Ana Marina Cabrerizo; Melanie Bonhomme; et al. "Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature". Nature Communications 13 1 (2022):
  2. Mar Cordero; Julia García-Fernández; Ivan C. Acosta; Ana Yepes; Jose Avendano-Ortiz; Clivia Lisowski; Babett Oesterreicht; et al. "The induction of natural competence adapts staphylococcal metabolism to infection". Nature Communications 13 1 (2022):
  3. Carmen Aguilar; Susana Costa; Claire Maudet; R. P. Vivek-Ananth; Sara Zaldívar-López; Juan J. Garrido; Areejit Samal; Miguel Mano; Ana Eulalio. "Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells". Nature Communications (2021):
  4. Lisowski, Clivia; Dias, Jane; Costa, Susana; Silva, Ricardo Jorge; Mano, Miguel; Eulalio, Ana. "Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication". Autophagy (2021): 1-16.
    Publicado • 10.1080/15548627.2021.1999561
  5. Aguilar, C.; Cruz, A.R.; Rodrigues Lopes, I.; Maudet, C.; Sunkavalli, U.; Silva, R.J.; Sharan, M.; et al. "Functional screenings reveal different requirements for host microRNAs in Salmonella and Shigella infection". Nature Microbiology 5 1 (2020): 192-205.
  6. Rodrigues Lopes, I.; Silva, R.J.; Caramelo, I.; Mano, M.; Eulalio, A.. "Shedding light on microRNA function via microscopy-based screening". Methods (2019):
  7. Aguilar, C.; Mano, M.; Eulalio, A.. "MicroRNAs at the Host–Bacteria Interface: Host Defense or Bacterial Offense". Trends in Microbiology 27 3 (2019): 206-218.
  8. Aguilar, C.; Mano, M.; Eulalio, A.. "Multifaceted roles of microRNAs in host-bacterial pathogen interaction". Microbiology Spectrum 7 3 (2019):
  9. Tawk, C.; Nigro, G.; Rodrigues Lopes, I.; Aguilar, C.; Lisowski, C.; Mano, M.; Sansonetti, P.; Vogel, J.; Eulalio, A.. "Stress-induced host membrane remodeling protects from infection by non-motile bacterial pathogens". The EMBO Journal 37 23 (2018):
  10. Tawk, C.; Sharan, M.; Eulalio, A.; Vogel, J.. "A systematic analysis of the RNA-targeting potential of secreted bacterial effector proteins". Scientific Reports 7 1 (2017):
  11. Sunkavalli, U.; Aguilar, C.; Silva, R.J.; Sharan, M.; Cruz, A.R.; Tawk, C.; Maudet, C.; Mano, M.; Eulalio, A.. "Analysis of host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia". PLoS Pathogens 13 4 (2017):
  12. Chowdhury, S.R.; Reimer, A.; Sharan, M.; Kozjak-Pavlovic, V.; Eulalio, A.; Prusty, B.K.; Fraunholz, M.; Karunakaran, K.; Rudel, T.. "Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission". Journal of Cell Biology 216 4 (2017): 1071-1089.
  13. Sharan, M.; Forstner, K.U.; Eulalio, A.; Vogel, J.. "APRICOT: An integrated computational pipeline for the sequence-based identification and characterization of RNA-binding proteins". Nucleic Acids Research 45 11 (2017): e96-e96.
  14. Eulalio, A.; Mano, M.. "MicroRNA Screening and the Quest for Biologically Relevant Targets". Journal of Biomolecular Screening 20 8 (2015): 1003-1017.
  15. Maudet, C.; Mano, M.; Sunkavalli, U.; Sharan, M.; Giacca, M.; Förstner, K.U.; Eulalio, A.. "Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection". Nature Communications 5 (2014):
  16. Maudet, C.; Mano, M.; Eulalio, A.. "MicroRNAs in the interaction between host and bacterial pathogens". FEBS Letters 588 22 (2014): 4140-4147.
  17. Huntzinger, E.; Kuzuoglu-Öztürk, D.; Braun, J.E.; Eulalio, A.; Wohlbold, L.; Izaurralde, E.. "The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets". Nucleic Acids Research 41 2 (2013): 978-994.
  18. Eulalio, A.; Mano, M.; Ferro, M.D.; Zentilin, L.; Sinagra, G.; Zacchigna, S.; Giacca, M.. "Functional screening identifies miRNAs inducing cardiac regeneration". Nature 492 7429 (2012): 376-381.
  19. Lovric, J.; Mano, M.; Zentilin, L.; Eulalio, A.; Zacchigna, S.; Giacca, M.. "Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins". Molecular Therapy 20 11 (2012): 2087-2097.
  20. Eulalio, A.; Schulte, L.N.; Voge, J.. "The mammalian microRNA response to bacterial infections". RNA Biology 9 6 (2012): 742-750.
  21. Schulte, L.N.; Eulalio, A.; Mollenkopf, H.-J.; Reinhardt, R.; Vogel, J.. "Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family". EMBO Journal 30 10 (2011): 1977-1989.
  22. Eulalio, A.; Fröhlich, K.S.; Mano, M.; Giacca, M.; Vogel, J.. "A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly". PLoS ONE 6 3 (2011):
  23. Heale, B.S.E.; Eulalio, A.; Schulte, L.; Vogel, J.; O'Connell, M.A.. "Analysis of a to I editing of miRNA in macrophages exposed to salmonella". RNA Biology 7 5 (2010): 621-627.
  24. Eulalio, A.; Tritschler, F.; Izaurralde, E.. "The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing". RNA 15 8 (2009): 1433-1442.
  25. Eulalio, A.; Huntzinger, E.; Nishihara, T.; Rehwinkel, J.; Fauser, M.; Izaurralde, E.. "Deadenylation is a widespread effect of miRNA regulation". RNA 15 1 (2009): 21-32.
  26. Eulalio, A.; Tritschler, F.; Budie;ttner, R.; Weichenrieder, O.; Izaurralde, E.; Truffault, V.. "The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing". Nucleic Acids Research 37 9 (2009): 2974-2983.
  27. Eulalio, A.; Helms, S.; Fritzsch, C.; Fauser, M.; Izaurralde, E.. "A C-terminal silencing domain in GW182 is essential for miRNA function". RNA 15 6 (2009): 1067-1077.
  28. Tritschler, F.; Braun, J.E.; Eulalio, A.; Truffault, V.; Izaurralde, E.; Weichenrieder, O.. "Structural Basis for the Mutually Exclusive Anchoring of P Body Components EDC3 and Tral to the DEAD Box Protein DDX6/Me31B". Molecular Cell 33 5 (2009): 661-668.
  29. Eulalio, A.; Huntzinger, E.; Izaurralde, E.. "GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay". Nature Structural and Molecular Biology 15 4 (2008): 346-353.
  30. Eulalio, A.; Huntzinger, E.; Izaurralde, E.. "Getting to the Root of miRNA-Mediated Gene Silencing". Cell 132 1 (2008): 9-14.
  31. Tritschler, F.; Eulalio, A.; Helms, S.; Schmidt, S.; Coles, M.; Weichenrieder, O.; Izaurralde, E.; Truffault, V.. "Similar modes of interaction enable trailer hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes". Molecular and Cellular Biology 28 21 (2008): 6695-6708.
  32. Jinek, M.; Eulalio, A.; Lingel, A.; Helms, S.; Conti, E.; Izaurralde, E.. "The C-terminal region of Ge-1 presents conserved structural features required for P-body localization". RNA 14 10 (2008): 1991-1998.
  33. Nunes-Correia, I.; Rodríguez, J.M.; Eulálio, A.; Carvalho, A.L.; Citovsky, V.; Simões, S.; Faro, C.; Salas, M.L.; Pedroso de Lima, M.C.. "African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection". Veterinary Microbiology 130 1-2 (2008): 47-59.
  34. Eulalio, A.; Behm-Ansmant, I.; Schweizer, D.; Izaurralde, E.. "P-body formation is a consequence, not the cause, of RNA-mediated gene silencing". Molecular and Cellular Biology 27 11 (2007): 3970-3981.
  35. Eulalio, A.; Behm-Ansmant, I.; Izaurralde, E.. "P bodies: At the crossroads of post-transcriptional pathways". Nature Reviews Molecular Cell Biology 8 1 (2007): 9-22.
  36. Eulalio, A.; Rehwinkel, J.; Stricker, M.; Huntzinger, E.; Yang, S.-F.; Doerks, T.; Dorner, S.; et al. "Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing". Genes and Development 21 20 (2007): 2558-2570.
  37. Tritschler, F.; Eulalio, A.; Truffault, V.; Hartmann, M.D.; Helms, S.; Schmidt, S.; Coles, M.; Izaurralde, E.; Weichenrieder, O.. "A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting". Molecular and Cellular Biology 27 24 (2007): 8600-8611.
  38. Eulálio, A.; Nunes-Correia, I.; Salas, J.; Salas, M.L.; Simões, S.; Pedroso de Lima, M.C.. "African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times". Virus Research 130 1-2 (2007): 18-27.
  39. Dorner, S.; Eulalio, A.; Huntzinger, E.; Izaurralde, E.. "Delving into the diversity of silencing pathways. Symposium on MicroRNAs and siRNAs: Biological Functions and Mechanisms". EMBO Reports 8 8 (2007): 723-729.
  40. Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Salas, J.; Salas, M.L.; Simões, S.; Pedroso De Lima, M.C.. "Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals". Journal of Virology 80 3 (2006): 1393-1404.
  41. Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Simões, S.; De Lima, M.C.P.. "Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities". Journal of Virology 78 18 (2004): 9731-9739.
  42. Nunes-Correia, I.; Eulálio, A.; Nir, S.; Pedroso De Lima, M.C.. "Caveolae as an additional route for influenza virus endocytosis in MDCK cells". Cellular and Molecular Biology Letters 9 1 (2004): 47-60.
  43. Nunes-Correia, I.; Eulálio, A.; Nir, S.; Düzgünes, N.; Ramalho-Santos, J.; Pedroso De Lima, M.C.. "Fluorescent probes for monitoring virus fusion kinetics: Comparative evaluation of reliability". Biochimica et Biophysica Acta - Biomembranes 1561 1 (2002): 65-75.
Capítulo de livro
  1. Aguilar, C.; Mano, M.; Eulalio, A.. "Multifaceted roles of microRNAs in host-bacterial pathogen interaction". In Bacteria and Intracellularity, editado por Pascale Cossart; Craig R. Roy; Philippe Sansonetti, 247-266. Estados Unidos: American Society of Microbiology, 2019.

Propriedade Intelectual

  1. Eulalio, Ana; Miguel Mano; Serena Zacchigna; Mauro Giacca. 2017. "MicroRNAs for cardiac regeneration through induction of cardiac myocyte proliferation".
  2. Luca Braga; Matteo Dal Ferro; Miguel Mano; Eulalio, Ana; Mauro Giacca. 2017. "MicroRNA hsa-miR-665 in cardiac hypertrophy".