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I am a biologist specialised in Environmental Toxicology, being dedicated especially to genotoxicology, toxicopathology and molecular toxicology. I am dedicated to the environment -human interface and I am nowadays putting the skills as toxicologist in service to drug discovery and marine natural products, especially animal toxins. I graduated in Biology from the Faculty of Sciences of the University of Lisbon (FCUL), followed by an M.Sc. in Ecological Modelling from Instituto Superior Técnico of Lisbon (IST-UTL) and a Ph.D. in Environmental Science from NOVA University of Lisbon (2010). ____ Within Toxicology, I am particularly interested in the dynamics of contaminant interactions, genotoxicants and the relation between pollutants and cancer. My current model of choice is the zebrafish. Developing studies involving multiple and multi-level biomarkers has been a paramount approach to investigate the intricate problems of exposure to realistic mixtures of toxicants, which may involve metals and many classes of organic toxicants, including potential carcinogens and emergent pollutants. I am particularly interested in the mechanisms of DNA damage and repair and how these relate to toxicopathological effects, from inflammation to carcinogenesis. More related to human health risk, I have also done extensive work within the domains of nanotoxicology, nanosafety and even nanomadicine, a field to which I was dedicated during my second post-doc at the Karolinska Institute of Stockholm, Sweden (2015-1016), with whom I continue to actively collaborate. ____ Within Marine Biotechnology I am particularly interested in marine biological toxins and other bio-reactive compounds, their origins, modes-of-action and potential applications. I am particularly interested in venomous or poisonous marine invertebrate eumetazoans, especially among the Polychaeta and the Mollusca. To address more mechanistic issues of toxicological pathways, either regarding pollutants or marine bioproducts, I have been dedicated to studies in vitro (with human and murine cell lines) and in vivo (using models such as marine bivalves, Daphnia, the zebrafish, murines and many more unconventional models). Molecular Biology, Bioninformatics, Genotoxicology and, especially, Histopathology have become my main technical expertise. I founded and lead the SeaTox Lab@UCIBIO in late 2017, based in the Department of Life Sciences of the School of Science and Technology of NOVA University of Lisbon, where I am an Auxiliary Professor since 2019, which succeeded a position as Auxiliary Researcher awarded in 2016. The SeaTox Lab is funded by several grants and projects of which I am PI and currently hosts two post-docs, three Ph.D. students, six M.Sc. students and many undergraduate trainees, all of which I am main supervisor. ____ I published more than 100 papers in SCI journals (about half in the last 5 years alone and without the participation of former supervisors), >75% in Q1 journals, most as first and/or corresponding author. I add several papers in proceedings, many entries in molecular databases like GenBank and GEO, a textbook on histopathology, four book chapters, a dozen invited talks or lectures, more than 30 oral presentations in international meetings alone (one yielded a best presentation award) and more than 60 posters. I attained an H-index = 26, with over 2200 citations. I review for about 50 top journals (I earned several Reviewing Excellence Certificates), from PLoS ONE and several Frontiers to Aquatic Toxicology and Environmental Research. I am an Associate Editor of Ecotoxicology, Frontiers in Marine Science and Editor of International Journal of Environmental Research and Public Health. In the latter, I coordinate two special issues on novel frontiers in Environmental Toxicology. I am a regular external reviewer in competitive international calls for projects and grants, the latest of which pertaining to the Human Frontiers in Science Program.
Identificação

Identificação pessoal

Nome completo
Pedro Manuel Brôa Costa
Data de nascimento
1978/10/27
Género
Masculino

Nomes de citação

  • Costa, Pedro M.
  • P.M. Costa
  • Pedro M. Costa

Identificadores de autor

Ciência ID
281C-7BD4-10C5
ORCID iD
0000-0002-9072-3522
Researcher Id
J-2962-2013
Scopus Author Id
27169731700

Endereços de correio eletrónico

  • pmcosta@fct.unl.pt (Profissional)

Telefones

Telefone
  • 212948530 Ext.: 11107 (Profissional)

Moradas

  • UCIBIO - Research Unit on Applied Molecular Biosciences. Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Monte de Caparica, Almada, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia
  • Ciências Naturais - Ciências Biológicas - Biologia Marinha
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Medicina Básica - Patologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Sueco Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2011/04/01
Concluído
Programa Doutoral em Ciências do Ambiente (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Biomarkers in Solea senegalensis Kaup, 1858 exposed to contaminated estuarine sediments: a multi–level approach" (TESE/DISSERTAÇÃO)
Approved
2005
Concluído
Mestrado em Ecologia, Gestão e Modelação dos Recursos Marinhos (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Análise da população de Hoplostethus mediterraneus Cuvier 1829 (Trachichtyidae: Beryciformes) ao largo da costa algarvia utilizando amostragem estratificada aleatória e modelos lineares generalizados" (TESE/DISSERTAÇÃO)
Approved
2001
Concluído
Biologia Aplicada aos Recursos Animais / Marinhos (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Teleósteos de profundidade: Biologia, Ecologia e espécies mais representativas na ZEE portuguesa" (TESE/DISSERTAÇÃO)
14
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2016/10/01 - 2019/12/17 Investigador Auxiliar (carreira) (Investigação) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015 - 2016 Pós-doutorado (Investigação) The Karolinska Institute, Institute of Environmental Medicine, Suécia
2011 - 2015 Pós-doutorado (Investigação) MARE - Marine and Environmental Sciences Centre, Portugal
2011 - 2015 Pós-doutorado (Investigação) Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
2005 - 2011 Investigador (Investigação) IMAR - Instituto do Mar, Portugal
2003 - 2005 Investigador (Investigação) IPIMAR - Instituto Português de Investigação Marinha, Portugal
2001 - 2003 Estagiário de Investigação (Investigação) Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2019/12/18 - Atual Professor Auxiliar (Docente Universitário) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2007 - 2015 Professor Auxiliar Convidado (Docente Universitário) Instituto Piaget, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2005 - 2007 Tutorial teaching Academia do Estudante, Portugal
Projetos

Bolsa

Designação Financiadores
2020/01 - Atual Eastern Tropical Pacific reef fish on the move: biodiversity reorganisation and societal consequences (EASMO) Deutsche Forschungsgemeinschaft
2016/10 - 2020/12/17 Colours and Toxins - A biotechnological approach to the value of marine annelids in biomedical research
IF/00265/2015
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
Fundação para a Ciência e Tecnologia (FCT)
2016/01 - 2018/12 Of pigments and toxins: an integrative approach to the biotechnological potential of a marine polychaete
PTDC/MAR-BIO/0113/2014
Investigador responsável
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
Fundação para a Ciência e a Tecnologia

Fundação para a Ciência e Tecnologia (FCT)
2011/05 - 2015/09 Analysis of the genotoxic potential of estuarine sediments and the DNA repair and apoptosis-related responses in human HepG2 cells
SFRH/BPD/72564/2010
Fundação para a Ciência e a Tecnologia, I.P.
2007/05 - 2011/04 Biomarkers in Solea senegalensis Kaup, 1858 exposed to contaminated estuarine sediments: a multi–level approach
SFRH/BD/28465/2006
Fundação para a Ciência e a Tecnologia, I.P.
1999 - 2002 CORRAM - Octopodid cephalopods: relation of the resources with the marine environment.
POCTI/CTA/1707/95
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2021/04 - Atual ExtremeOceans - Unravelling evolutionary physiology landscapes of coastal marine fauna under extreme temperatures using a multi-layer Systems Biology approach Fundação para a Ciência e a Tecnologia
2021/02 - Atual SeaSenseX - Next-generation microsensors for marine mutagens and carcinogens Fundação para a Ciência e a Tecnologia
2018/10 - Atual WormALL– Marine invertebrates as source of novel biotoxins: Investigating function and application through Polychaeta venomics
PTDC/BTA-BTA/28650/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
2016/06 - Atual 3Qs for quality - Development of molecular sensors and technologies for seafood quality assessment
PTDC/MAR-BIO/6044/2014
Investigador
Fundação para a Ciência e Tecnologia (FCT)
Concluído
2014 - Atual RD Units Strategic Plan - 2013/2015 - OE
UID/MAR/04292/2013
Fundação para a Ciência e a Tecnologia, I.P.
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020/01/01 - 2021/12/31 The MARVEN Project: The Portuguese biotechnological database for marine animal venoms and toxins
FA_05_2017_007
Investigador responsável
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
Fundo Azul
Em curso
2018 - 2021 MBSTox - Multifunctional biomolecular systems for new methods of decontamination, protection and toxicological assessment
PTDC/BIA-MIB/31864/2017
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2015 - 2018 PLASTOX - Direct and indirect ecotoxicological impacts of microplastics on marine organisms
Investigador
JPI Oceans
2015 - 2016 SUN - Sustainable Nanotechnologies Project
EU FP7 contract nº 604305
Investigador
European Comission CORDIS
Concluído
2012/03 - 2015/08 A proteomic study on the combined effects of pCO2 and temperature on different life stages of the marine fish Sparus aurata.
Investigador
Fundação para a Ciência e a Tecnologia
2013/06 - 2014/09 Chlorophyll-like pigments in a marine polychaete – evolutionary relevance and biotechnological value
EXPL/MAR–EST/1236/2012, FCT
EXPL/MAREST/1236/2012, FCT
Fundação para a Ciência e a Tecnologia, I.P.

Fundação para a Ciência e a Tecnologia
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 284 - 2011-2012
PEst-C/MAR/UI0284/2011
PEst-OE/CED/UI2861/2011
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Algarve, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Universidade Nova de Lisboa Unidade de Investigação Educação e Desenvolvimento, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/11 - 2012/04 Integrating molecular approaches into marine biodiversity research in Portugal: implementing DNA barcoding and investigating phylogeographic patterns
Investigador
Fundação para a Ciência e a Tecnologia
2009 - 2012 HERA – Environmental Risk Assessment of a contaminated estuarine environment: A case study
PTDC/SAU-ESA/100107/2008
Investigador
Fundação para a Ciência e a Tecnologia
2005/11 - 2007/12 WEIGHT OF EVIDENCE (WOE) APPROACHES FOR SEDIMENT RISK ASSESSMENT: SADO ESTUARY CASE STUDY
Investigador
Fundação para a Ciência e a Tecnologia
2001/09 - 2005/06 Development of an Information and environmental management system for Sado Estuary
Provided by PTCRIS: 35137
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Costa, Pedro M.. "Microscopy as a tool in drug-discovery marine biotechnology: a marine annelid as case study". 2018.
    10.1080/07853890.2018.1427445
  2. Martins, C.; Neuparth, T.; Costa, M.H.; Santos, M.M.; Costa, P.M.. "Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: Histopathological evaluation". 2013.
    10.13140/2.1.2716.8003
  3. Gonçalves, C.; Martins, M.; Diniz, M.S.; Costa, M.H.; Caeiro, S.; Costa, P.M.. "Endocrine disruption in soles collected from an estuarine area: comparison with sediment contamination profiles". 2013.
    10.13140/2.1.1774.8163
  4. Santos, J.; Costa, P.M.; Martins, M.; Costa, M.H.. "Comparative effects of sediments contaminated by carcinogenic and non-carcinogenic PAHs in Dicentrarchus labrax: a semi-quantitative histopathological approach". 2013.
    10.13140/2.1.2823.3928
  5. Candeias, M.; Diniz, M.S.; Costa, P.M.; Peres, I.. "Contaminação e descontaminação de cobre em Carassius auratus L. 1758: efeitos histopatológicos nas brânquias e no fígado". 2007.
  6. Santos, H.M.; Diniz, M.S.; Costa, P.M.; Peres, I.; Costa, M.H.; Capelo-Martinez, J.L.. "Utilização de Corbicula fluminea Mühlfeld, 1844, como indicador de contaminação por arsénio: avaliação da capacidade de resposta através da determinação de metalotioninas e arsénio nos tecidos". 2006.
Artigo em revista
  1. Maria Alcaide; Inês Moutinho Cabral; Lara Carvalho; Vera M. Mendes; António P. Alves de Matos; Bruno Manadas; Leonor Saúde; Mariaelena D’Ambrosio; Pedro M. Costa. "A Comparative Analysis of the Venom System between Two Morphotypes of the Sea Anemone Actinia equina". Animals (2024): https://doi.org/10.3390/ani14060981.
    10.3390/ani14060981
  2. Ana P. Rodrigo; Inês Moutinho Cabral; António Alexandre; Pedro M. Costa. "Exploration of Toxins from a Marine Annelid: An Analysis of Phyllotoxins and Accompanying Bioactives". Animals (2024): https://doi.org/10.3390/ani14040635.
    10.3390/ani14040635
  3. Roma, Joana; Missionário, Madalena; Madeira, Carolina; Matos, Ana Rita; Vinagre, Catarina; Costa, Pedro M.; Duarte, Bernardo. "Comparative responses and effects of exposure to metallic and nanoparticle zinc in the mussel Mytilus galloprovincialis". Estuarine, Coastal and Shelf Science 297 (2024): 108616. http://dx.doi.org/10.1016/j.ecss.2024.108616.
    10.1016/j.ecss.2024.108616
  4. Sónia Campos; Ana P. Rodrigo; Inês Moutinho Cabral; Vera M. Mendes; Bruno Manadas; Mariaelena D’Ambrosio; Pedro M. Costa. "An Exploration of Novel Bioactives from the Venomous Marine Annelid Glycera alba". Toxins (2023): https://doi.org/10.3390/toxins15110655.
    10.3390/toxins15110655
  5. Cátia Gonçalves; António P. Alves de Matos; Pedro M. Costa. "Comparative analysis of the jaw apparatus of three marine annelids using scanning electron microscopy: Microstructure and elemental composition". Journal of Anatomy (2023): https://doi.org/10.1111/joa.13910.
    10.1111/joa.13910
  6. João D. Vitorino; Pedro M. Costa. "After a Century of Research into Environmental Mutagens and Carcinogens, Where Do We Stand?". International Journal of Environmental Research and Public Health (2023): https://doi.org/10.3390/ijerph20021040.
    10.3390/ijerph20021040
  7. Ana F. Lopes; Robyn Murdoch; Sara Martins-Cardoso; Carolina Madeira; Pedro M. Costa; Ana S. Félix; Rui F. Oliveira; et al. "Differential Effects of Food Restriction and Warming in the Two-Spotted Goby: Impaired Reproductive Performance and Stressed Offspring". Fishes (2022): https://doi.org/10.3390/fishes7040194.
    10.3390/fishes7040194
  8. D'Ambrosio, Mariaelena; Ramos, Íris; Martins, Carla; Costa, Pedro M.. "An investigation into the toxicity of tissue extracts from two distinct marine Polychaeta". Toxicon: X 14 (2022): 100116. http://dx.doi.org/10.1016/j.toxcx.2022.100116.
    Acesso aberto • Publicado • 10.1016/j.toxcx.2022.100116
  9. Rodrigo, Ana P.; Lopes, Ana; Pereira, Ricardo; Anjo, Sandra I.; Manadas, Bruno; Grosso, Ana R.; Baptista, Pedro V.; Fernandes, Alexandra R.; Costa, Pedro M.. "Endogenous Fluorescent Proteins in the Mucus of an Intertidal Polychaeta: Clues for Biotechnology". Marine Drugs 20 4 (2022): 224. http://dx.doi.org/10.3390/md20040224.
    Acesso aberto • 10.3390/md20040224
  10. Inês Moutinho Cabral; Carolina Madeira; Ana R. Grosso; Pedro M. Costa. "A drug discovery approach based on comparative transcriptomics between two toxin-secreting marine annelids: Glycera alba and Hediste diversicolor". Molecular Omics (2022): https://doi.org/10.1039/D2MO00138A.
    10.1039/D2MO00138A
  11. Pedro M. Costa. "Current aspects of DNA damage and repair in ecotoxicology: a mini-review". Ecotoxicology (2021): https://doi.org/10.1007/s10646-021-02487-2.
    10.1007/s10646-021-02487-2
  12. Maria Leonor Santos; Mariaelena D’Ambrosio; Ana P. Rodrigo; A. Jorge Parola; Pedro M. Costa. "A Transcriptomic Approach to the Metabolism of Tetrapyrrolic Photosensitizers in a Marine Annelid". Molecules (2021): https://doi.org/10.3390/molecules26133924.
    10.3390/molecules26133924
  13. Mariaelena D’Ambrosio; Cátia Gonçalves; Mariana Calmão; Maria Rodrigues; Pedro M. Costa. "Localization and Bioreactivity of Cysteine-Rich Secretions in the Marine Gastropod Nucella lapillus". Marine Drugs 19 5 (2021): 276-276. https://doi.org/10.3390/md19050276.
    10.3390/md19050276
  14. Pedro M. Costa. "Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles". NanoImpact (2021):
    10.1016/j.impact.2021.100313
  15. Pedro M. Costa. "Cephalotoxins: A Hotspot for Marine Bioprospecting?". Frontiers in Marine Science (2021): https://www.frontiersin.org/articles/10.3389/fmars.2021.647344/full.
    10.3389/FMARS.2021.647344
  16. Ana P. Rodrigo; Ana R. Grosso; Pedro V. Baptista; Alexandra R. Fernandes; Pedro M. Costa. "A Transcriptomic Approach to the Recruitment of Venom Proteins in a Marine Annelid". Toxins (2021): https://doi.org/10.3390/toxins13020097.
    10.3390/toxins13020097
  17. Ana P. Rodrigo; Vera M. Mendes; Bruno Manadas; Ana R. Grosso; António P. Alves de Matos; Pedro V. Baptista; Pedro M. Costa; Alexandra R. Fernandes. "Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer Cells". Marine Drugs (2021): https://doi.org/10.3390/md19010031.
    10.3390/md19010031
  18. Pedro M. Costa. "Different sensitivity to heatwaves across the life cycle of fish reflects phenotypic adaptation to environmental niche". Marine Environmental Research (2020): 105192-105192. http://dx.doi.org/10.1016/j.marenvres.2020.105192.
    10.1016/j.marenvres.2020.105192
  19. Pedro M. Costa. "On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression". Frontiers in Public Health (2020): http://dx.doi.org/10.3389/fpubh.2020.00495.
    10.3389/fpubh.2020.00495
  20. Cátia Gonçalves; Pedro M. Costa. "Histochemical detection of free thiols in glandular cells and tissues of different marine Polychaeta". Histochemistry and Cell Biology 154 3 (2020): 315-325. https://doi.org/10.1007/s00418-020-01889-3.
    10.1007/s00418-020-01889-3
  21. Mariaelena D’Ambrosio; Ana Catarina Santos; Alfonso Alejo-Armijo; A. Jorge Parola; Pedro M. Costa. "Light-Mediated Toxicity of Porphyrin-Like Pigments from a Marine Polychaeta". Marine Drugs (2020): https://doi.org/10.3390/md18060302.
    10.3390/md18060302
  22. Pedro M. Costa. "Metal body burden and tissue oxidative status in the bivalve Venerupis decussata from Tunisian coastal lagoons". Marine Environmental Research (2020): http://dx.doi.org/10.1016/j.marenvres.2020.105000.
    10.1016/j.marenvres.2020.105000
  23. Costa, Pedro M.. "Technical Updates to the Comet Assay In Vivo for Assessing DNA Damage in Zebrafish Embryos from Fresh and Frozen Cell Suspensions". Zebrafish (2020): http://dx.doi.org/10.1089/zeb.2020.1857.
    10.1089/zeb.2020.1857
  24. Costa, Pedro M.. "The complexity of porphyrin-like pigments in a marine annelid sheds new light on haem metabolism in aquatic invertebrates". Scientific Reports (2019): http://dx.doi.org/10.1038/s41598-019-49433-1.
    10.1038/s41598-019-49433-1
  25. Costa, Pedro M.. "The State-of-the Art of Environmental Toxicogenomics: Challenges and Perspectives of “Omics” Approaches Directed to Toxicant Mixtures". International Journal of Environmental Research and Public Health (2019): http://dx.doi.org/10.3390/ijerph16234718.
    10.3390/ijerph16234718
  26. Pedrosa, Pedro; Corvo, M. Luísa; Ferreira-Silva, Margarida; Martins, Pedro; Carvalheiro, Manuela Colla; Costa, Pedro M.; Martins, Carla; et al. "Targeting Cancer Resistance via Multifunctional Gold Nanoparticles". International Journal of Molecular Sciences 20 21 (2019): 5510. http://dx.doi.org/10.3390/ijms20215510.
    10.3390/ijms20215510
  27. Cunha, M.; Martins, C.; Grosso, A.R.; Costa, P.M.. "Mytilus galloprovincialis CYP1A-like mRNAs reveal closer proximity of mytilid CYP1A to the eumetazoan CYP2 family". Aquatic Toxicology 214 (2019): 105260. http://dx.doi.org/10.1016/j.aquatox.2019.105260.
    10.1016/j.aquatox.2019.105260
  28. Costa, Pedro M.. "New lessons from ancient life: marine invertebrates as a source of new drugs". Annals of Medicine (2019): http://dx.doi.org/10.1080/07853890.2018.1561901.
    10.1080/07853890.2018.1561901
  29. Gonçalves, Cátia; Martins, Marta; Sobral, Paula; Costa, Pedro M.; Costa, Maria H.. "An assessment of the ability to ingest and excrete microplastics by filter-feeders: A case study with the Mediterranean mussel". Environmental Pollution 245 (2019): 600-606. http://dx.doi.org/10.1016/j.envpol.2018.11.038.
    10.1016/j.envpol.2018.11.038
  30. Rodrigo, A.P.; Costa, P.M.. "The hidden biotechnological potential of marine invertebrates: The Polychaeta case study". Environmental Research In press (2019):
    10.1016/j.envres.2019.03.048
  31. RODRIGO, A.P.C.; MARTINS, C.; ALVES DE MATOS, A.P.; COSTA, M.H.; COSTA, P.M.; Rodrigo, A.P.. "A morphoanatomical approach to the adaptive features of the epidermis and proboscis of a marine Polychaeta: Eulalia viridis (Phyllodocida: Phyllodocidae).". Journal of Anatomy In press 5 (2018): 567-579. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052458867&partnerID=MN8TOARS.
    10.1111/JOA.12870
  32. Martins, M.; Silva, A.; Costa, M.H.; Miguel, C.; Costa, P.M.. "Co-exposure to environmental carcinogens in vivo induces neoplasia-related hallmarks in low-genotoxicity events, even after removal of insult". Scientific Reports 8 3469 (2018):
    10.1038/s41598-018-21975-w
  33. ALVES-BARROCO, C.; ROMA-RODRIGUES, C.; RAPOSO, L.R.; BRÁS, C.; DINIZ, M.; COSTA, P.M.; FERNANDES, A.R.; SANTOS-SANCHES, I.. "Streptococcus dysgalactiae subsp. dysgalactiae isolated from milk of the bovine udder as emerging pathogens: in vitro and in vivo infection of human cells and zebrafish as biological models". Micriobiology OPEN In press (2018):
    10.1002/mbo3.623
  34. Cuevas, N.; Martins, M.; Rodrigo, A.P.; Martins, C.; Costa, P.M.. "Explorations on the ecological role of toxin secretion and delivery in jawless predatory Polychaeta". Scientific Reports In press (2018):
    10.1038/s41598-018-26031-1
  35. Cuevas, N; Martins, M; Costa, P.M.. "Risk assessment of pesticides in estuaries: A review addressing the persistence of an old problem in complex environments". Ecotoxicology In press (2018):
    10.1007/s10646-018-1910-z
  36. Líbalová, H.; Costa, P.M.; Olsson, M.; Farcal, L.; Ortelli, S.; Blosi, M.; Topinka, J.; Costa, A.L.; Fadeel, B.. "Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution". Chemosphere 196 (2018): 482-493. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040120289&partnerID=MN8TOARS.
    10.1016/j.chemosphere.2017.12.182
  37. Costa, Pedro M.. "Of pigments and toxins: an integrative approach to the biotechnological potential of a marine polychaete". Impact (2017): http://dx.doi.org/10.21820/23987073.2017.11.62.
    10.21820/23987073.2017.11.62
  38. Costa, P.M.; Gosens, I.; Williams, A.; Farcal, L.; Pantano, D.; Brown, D.M.; Stone, V.; et al. "Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles". Journal of Applied Toxicology In press (2017):
    10.1002/jat.3548
  39. Gonçalves, C.; Martins, M.; Costa, M.H.; Costa, P.M.. "Development of a method for the detection of polystyrene microplastics in paraffin-embedded histological sections". Histochemistry and Cell biology In press (2017):
    10.1007/s00418-017-1613-1
  40. BHATTACHARYA, K.; SACCHETTI, C.; COSTA, P.M.; SOMMERTUNE, J.; BRANDNER, B.D.; MAGRINI, A.; ROSATO, N.; et al. "Nitric Oxide-Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery". Advanced Healthcare Materials In Press (2017):
    10.1002/adhm.201700916
  41. Bhattacharya, K.; Kiliç, G.; Costa, P.M.; Fadeel, B.. "Cytotoxicity screening and cytokine profiling of nineteen nanomaterials enables hazard ranking and grouping based on inflammogenic potential  ". Nanotoxicology In press (2017): http://dx.doi.org/10.1080/17435390.2017.1363309.
    10.1080/17435390.2017.1363309
  42. Rodrigo, A.P.; Costa, P.M.. "The role of the cephalopod digestive gland in the storage and detoxification of marine pollutants". Frontiers in Physiology 8 232 (2017):
    10.3389/fphys.2017.00232
  43. Fernandes, Alexandra R.; Jesus, Joao; Martins, Pedro; Figueiredo, Sara; Rosa, Daniela; Martins, Luisa M. R. D. R. S.; Corvo, Maria Luisa; et al. "Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents". Journal of Controlled Release 245 (2017): 52-61. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000396474500005&KeyUID=WOS:000396474500005.
    10.1016/j.jconrel.2016.11.021
  44. Madeira, D.; Araújo, D.; Vitorino, R.; Costa, P.M.; Capelo, J.-L.; Vinagre, C.; Diniz, M.. "Molecular plasticity under ocean warming: proteomics and fitness data provides clues for a better understanding of the thermal tolerance in fish". Frontiers in Physiology In press (2017):
    10.3389/fphys.2017.00825
  45. Pereira, K.C.; Costa, P.M.; Costa, M.H.; Luque, Á.; DelValls Casillas, Á.; Riba López, I.. "Effects of the increase of temperature and CO2 concentration on polychaetae Nereis diversicolor: simulating extreme scenarios of climate change in marine sediments.". Hydrobiologia in press (2016):
    10.1007/s10750-016-2656-3
  46. Diana MadeiraPedro M. CostaCatarina VinagreMário S. Diniz. "When warming hits harder: survival, cellular stress and thermal limits ofSparus aurata larvae under global change". Marine Biology 163 4 (2016): 1432-1793  .
    10.1007/s00227-016-2856-4
  47. Caeiro, S.; Vaz-Fernandes, P.,; Martinho, A.P.; Costa, P.M.; Silva, M.J.,; Lavinha, J.; Matias-Dias, C; Machado, A.; Costa, M.H.. "Environmental risk assessment in a contaminated estuary: An integrated weight of evidence approach as a decision support tool". Ocean and Coastal Management In press (2016):
    10.1016/j.ocecoaman.2016.09.026
  48. Martins, Marta; Ferreira, Ana M.; Costa, Maria H.; Costa, Pedro M.. "Comparing the Genotoxicity of a Potentially Carcinogenic and a Noncarcinogenic PAH, Singly, and in Binary Combination, on Peripheral Blood Cells of the European Sea Bass". Environmental Toxicology 31 11 (2016): 1307-1318. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000388616700002&KeyUID=WOS:000388616700002.
    10.1002/tox.22135
  49. Martins, M.; Santos, J.M.; Costa, M.H.; Costa, P.M.. "Applying quantitative and semi-quantitative histopathology to address the interaction between sediment-bound polycyclic aromatic hydrocarbons in fish gills". Ecotoxicology and Environmental Safety In press. (2016):
    10.1016/j.ecoenv.2016.04.019
  50. Rodrigo, A.P.; Costa, M.H.; Costa, P.M.; Rodrigo, A.. "Microanatomical alterations in the gut of an marine polychaete ( Eulalia viridis , Errantia: Phyllodocidae) during the digestive process". Microscopy and Microanalysis 21 S6 (2015): 12-13. http://dx.doi.org/10.1017/s1431927614013737.
    10.1017/s1431927614013737
  51. Cuevas, N.; Zorita, K.; Franco, J.; Costa, P.M.; Larreta, J.. "Multi-organ histopathology in gobies (Pomatoschistus spp.) for estuarine environmental risk assessment: a case study in the Ibaizabal estuary (SE Bay of Biscay)". Estuarine, Coastal and Shelf Science In press (2015):
    10.1016/j.ecss.2015.11.023
  52. Madeira, D.; Mendonça, V.; Dias, M.; Costa, P.M.; Vinagre, C.; Diniz, M.S. "Physiological, cellular and molecular thermal stress response of intertidal shrimps with different vertical distributions: Palaemon elegans and Palaemon serratus". Comparative Physiology and Biochemistry, Part A 183 (2015): 107-115.
    10.1016/j.cbpa.2014.12.039
  53. CUEVAS, N.; ZORITA, I.; COSTA, P.M.; FRANCO, J.; LARRETA, J.. "Development of histopathological indices in the digestive gland and gonad of mussels: integration with contamination levels and effects of confounding factors". Aquatic Toxicology In press (2015):
    10.1016/j.aquatox.2015.03.011
  54. Rodrigo, A.P.; Costa, M.H.; Alves de Matos, A.P.; Carrapiço, F.; Costa, P.M.. "A study on the digestive physiology of a marine polychaete (Eulalia viridis) through microanatomical changes of epithelia during the digestive cycle". Microscopy and Microanalysis 21 1 (2015): 91-101.
    10.1017/S143192761401352X
  55. Martins, Marta; Costa, Pedro M.. "The comet assay in Environmental Risk Assessment of marine pollutants: applications, assets and handicaps of surveying genotoxicity in non-model organisms". Mutagenesis 30 1 (2015): 89-106.
    10.1093/mutage/geu037
  56. DE LAPUENTE, J.; LOURENÇO, J.; MENDO, S.; BORRÀS, M.; MARTINS, M.; COSTA, P.M.; PACHECO, M.. "The Comet Assay and its applications in the field of ecotoxicology: a mature tool that continues to expand its perspectives". Frontiers in Genetics In press (2015):
    10.3389/fgene.2015.00180
  57. Martins, M.; Santos, J.; Diniz, M.S.; Ferreira, A.M.; Costa, M.H.; Costa, P.M.. "Effects of carcinogenic versus non-carcinogenic AHR-active PAHs and their mixtures: lessons from ecological relevance". Environmental Research In Press (2015):
    10.1016/j.envres.2015.02.010
  58. Pinto, M.; Louro, H.; Costa, P.M.; Caeiro, S.; Silva, M.J.. "Exploring the potential interference of estuarine sediment contaminants with DNA repair in HepG2 cells". Journal of Environmental Toxicology and Health, Part A In press (2015):
    10.1080/15287394.2015.1006712
  59. Mendo, Ana Soraia; Figueiredo, Sara; Roma-Rodrigues, Catarina; Videira, Paula A.; Ma, Zhen; Diniz, Mario; Larguinho, Miguel; et al. "Characterization of antiproliferative potential and biological targets of a copper compound containing 4'-phenyl terpyridine". Journal of Biological Inorganic Chemistry 20 6 (2015): 935-948. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=CCC&KeyUT=CCC:000360224000002&KeyUID=CCC:000360224000002.
    10.1007/s00775-015-1277-z
  60. CUEVAS, N.; COSTA, P.M.; FRANCO, J.; LARRETA, J.; QUINCONCES, I.; ZORITA, I.. "Histopathological indices in sole (Solea solea) and hake (Merluccius merluccius) for implementation of the European Marine Strategy Framework Directive along the Basque continental shelf (SE Bay of Biscay)". Marine Pollution Bulletin In press (2015):
    10.1016/j.marpolbul.2015.02.030
  61. Martins, C.; Alves de Matos, A.P.; Costa, M.H.; Costa, P.M.. "Alterations in juvenile flatfish gill epithelia induced by sediment-bound toxicants: a comparative in situ and ex situ study". Marine Environmental Research In press (2015):
    10.1016/j.marenvres.2015.10.007
  62. Costa, P.M.; Fadeel, B.. "Emerging systems biology approaches in nanotoxicology: Towards a mechanism-based understanding of nanomaterial". Toxicology and Applied Pharmacology in press (2015):
    10.1016/j.taap.2015.12.014
  63. Cuevas, N.; Zorita, I.; Costa, P.M.; Larreta, J.; Franco, J.. "Histopathological baseline levels and confounding factors in common sole (Solea solea) for marine environmental risk assessment". Marine Environmental Research In press (2015):
    10.1016/j.marenvres.2015.09.002
  64. Costa, Pedro. "An integrative assessment to determine the genotoxic hazard of estuarine sediments: combining cell and whole-organism responses". Frontiers in Genetics (2014): http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00437/abstract.
    10.3389/fgene.2014.00437
  65. Costa, Pedro. "Metabolic and histopathological alterations in the marine bivalve Mytilus galloprovincialis induced by chronic exposure to acrylamide". Environmental Research (2014): http://dx.doi.org/10.1016/j.envres.2014.09.004.
    10.1016/j.envres.2014.09.004
  66. Conde, J.; Larguinho, M.; Cordeiro, A.; Raposo, L.R.; Costa, P.M.; Santos, S.; Diniz, M.S.; Fernandes, A.R.; Baptista, P.V.. "Gold-nanobeacons for gene therapy: Evaluation of genotoxicity, cell toxicity and proteome profiling analysis". Nanotoxicology 8 5 (2014): 521-532. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888082442&partnerID=MN8TOARS.
    10.3109/17435390.2013.802821
  67. Madeira, D.. "Histopathological alterations, physiological limits, and molecular changes of juvenile Sparus aurata in esponse to thermal stress". Marine Ecology Progress Series 505 (2014): 253-266.
    10.3354/meps10794
  68. Louro, H.; Tavares, A.; Vital, N.; Costa, P.M.; Alverca, E.; Zwart, E.; de Jong, W.H.; et al. "Integrated approach to the in vivo genotoxic effects of a titanium dioxide nanomaterial using LacZ plasmid-based transgenic mice". Environmental and Molecular Mutagenesis (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84894727637&partnerID=MN8TOARS.
    10.1002/em.21864
  69. Gonçalves, C.; Martins, M.; Diniz, M.S.; Costa, M.H.; Caeiro, S.; Costa, P.M.. "May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis". Marine Environmental Research (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84900740057&partnerID=MN8TOARS.
    10.1016/j.marenvres.2014.04.012
  70. Costa, P.M.; Rodrigo, A.P.; Costa, M.H.. "Microstructural and histochemical advances on the digestive gland of the common cuttlefish, Sepia officinalis L.". Zoomorphology 133 1 (2014): 59-69. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893961867&partnerID=MN8TOARS.
    10.1007/s00435-013-0201-8
  71. Pinto, M.; Costa, P.M.; Louro, H.; Costa, M.H.; Lavinha, J.; Caeiro, S.; Silva, M.J.. "Human hepatoma cells exposed to estuarine sediment contaminant extracts permitted the differentiation between cytotoxic and pro-mutagenic fractions". Environmental Pollution 185 (2014): 141-148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888599414&partnerID=MN8TOARS.
    10.1016/j.envpol.2013.10.034
  72. Madeira, D.; Dias, M.; Roma, J.; costa, P.M.; Vinagre, C.; Diniz, M.S.. "Physiological and biochemical thermal stress response of the intertidal rock goby Gobius paganellus.". Ecological Indicators 46 (2014): 232-239.
    10.1016/j.ecolind.2014.06.029
  73. Neuparth, T.; Martins, C.; De Los Santos, C.B.; Costa, M.H.; Martins, I.; Costa, P.M.; Santos, M.M.. "Hypocholesterolaemic pharmaceutical simvastatin disrupts reproduction and population growth of the amphipod Gammarus locusta at the ng/L range.". Aquatic Toxicology (2014):
    10.1016/j.aquatox.2014.07.009
  74. Pinto, M.; Costa, P.M.; Louro, H.; Costa, M.H.; Lavinha, J.; Caeiro, S.; Silva, M.J.. "Determining oxidative and non-oxidative genotoxic effects driven by estuarine sediment contaminants on a human hepatoma cell line". Science of the Total Environment 478 (2014): 25-35. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893752547&partnerID=MN8TOARS.
    10.1016/j.scitotenv.2014.01.084
  75. Madeira, D.; Vinagre, C.; Rosa, R.; Costa, P.M.; Costa, M.H.; Caeiro, S.; Galésio, M.; et al. "Sea warming affects bream (Sparus aurata) tissues and stress proteins (HSP70)". Microscopy and Microanalysis 19 S4 (2013): 83-84. http://dx.doi.org/10.1017/s1431927613001037.
    10.1017/s1431927613001037
  76. Martins, M.; Costa, P.M.; Ferreira, A.M.; Costa, M.H.. "Comparative DNA damage and oxidative effects of carcinogenic and non-carcinogenic sediment-bound PAHs in the gills of a bivalve". Aquatic Toxicology 142-143 (2013): 85-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882805054&partnerID=MN8TOARS.
    10.1016/j.aquatox.2013.07.019
  77. Larguinho, M.; Costa, P.M.; Sousa, G.; Costa, M.H.; Diniz, M.S.; Baptista, P.V.. "Histopathological findings on Carassius auratus hepatopancreas upon exposure to acrylamide: Correlation with genotoxicity and metabolic alterations". Journal of Applied Toxicology (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84885342542&partnerID=MN8TOARS.
    10.1002/jat.2936
  78. Gonçalves, C.; Martins, M.; Costa, M.H.; Caeiro, S.; Costa, P.M.. "Ecological risk assessment of impacted estuarine areas: Integrating histological and biochemical endpoints in wild Senegalese sole". Ecotoxicology and Environmental Safety 95 (2013): 202-211. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880329507&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2013.06.004
  79. Lobo, J.; Costa, P.M.; Teixeira, M.A.L.; Ferreira, M.S.G.; Costa, M.H.; Costa, F.O.. "Enhanced primers for amplification of DNA barcodes from a broad range of marine metazoans". BMC Ecology 13 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84883611456&partnerID=MN8TOARS.
    10.1186/1472-6785-13-34
  80. Costa, P.M.; Carreira, S.; Costa, M.H.; Caeiro, S.. "Development of histopathological indices in a commercial marine bivalve (Ruditapes decussatus) to determine environmental quality". Aquatic Toxicology 126 (2013): 442-454. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871817413&partnerID=MN8TOARS.
    10.1016/j.aquatox.2012.08.013
  81. Costa, P.M.; Caeiro, S.; Costa, M.H.. "Multi-organ histological observations on juvenile Senegalese soles exposed to low concentrations of waterborne cadmium". Fish Physiology and Biochemistry 39 2 (2013): 143-158. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875217223&partnerID=MN8TOARS.
    10.1007/s10695-012-9686-1
  82. Rodrigo, A.P.; Costa, P.M.; Costa, M.H.; Caeiro, S.. "Integration of sediment contamination with multi-biomarker responses in a novel potential bioindicator (Sepia officinalis) for risk assessment in impacted estuaries". Ecotoxicology 22 10 (2013): 1538-1554. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888856472&partnerID=MN8TOARS.
    10.1007/s10646-013-1140-3
  83. Carreira, S.; Costa, P.M.; Martins, M.; Lobo, J.; Costa, M.H.; Caeiro, S.. "Ecotoxicological heterogeneity in transitional coastal habitats assessed through the integration of biomarkers and sediment-contamination profiles: A case study using a commercial clam". Archives of Environmental Contamination and Toxicology 64 1 (2013): 97-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871806601&partnerID=MN8TOARS.
    10.1007/s00244-012-9812-1
  84. Costa, P.M.; Carreira, S.; Lobo, J.; Costa, M.H.. "Molecular detection of prokaryote and protozoan parasites in the commercial bivalve Ruditapes decussatus from southern Portugal". Aquaculture 370-371 (2012): 61-67. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867804853&partnerID=MN8TOARS.
    10.1016/j.aquaculture.2012.10.006
  85. Costa, P.M.; Caeiro, S.; Vale, C.; Delvalls, T.Á.; Costa, M.H.. "Can the integration of multiple biomarkers and sediment geochemistry aid solving the complexity of sediment risk assessment? A case study with a benthic fish". Environmental Pollution 161 (2012): 107-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-80155183670&partnerID=MN8TOARS.
    10.1016/j.envpol.2011.10.010
  86. Costa, P.M.; Milhinhos, A.; Simões, M.; Marum, L.; Oliveira, A.M.; Costa, M.H.; Miguel, C.. "Determining DNA strand breakage from embryogenic cell cultures of a conifer species using the single-cell gel electrophoresis assay". Tree Genetics and Genomes 8 2 (2012): 425-430. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858619348&partnerID=MN8TOARS.
    10.1007/s11295-011-0434-y
  87. Martins, M.; Costa, P.M.; Raimundo, J.; Vale, C.; Ferreira, A.M.; Costa, M.H.. "Impact of remobilized contaminants in Mytilus edulis during dredging operations in a harbour area: Bioaccumulation and biomarker responses". Ecotoxicology and Environmental Safety 85 (2012): 96-103. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866994586&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2012.08.008
  88. Costa, P.M.; Costa, M.H.. "Development and application of a novel histological multichrome technique for clam histopathology". Journal of Invertebrate Pathology 110 3 (2012): 411-414. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861930141&partnerID=MN8TOARS.
    10.1016/j.jip.2012.04.013
  89. Costa, P.M.; Chicano-Gálvez, E.; Caeiro, S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "Hepatic proteome changes in Solea senegalensis exposed to contaminated estuarine sediments: A laboratory and in situ survey". Ecotoxicology 21 4 (2012): 1194-1207. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862893337&partnerID=MN8TOARS.
    10.1007/s10646-012-0874-7
  90. Costa, P.M.; Caeiro, S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; Vale, C.; DelValls, T. Á; Costa, M.H.. "Estuarine ecological risk based on hepatic histopathological indices from laboratory and in situ tested fish". Marine Pollution Bulletin 62 1 (2011): 55-65. http://www.scopus.com/inward/record.url?eid=2-s2.0-78751637331&partnerID=MN8TOARS.
    10.1016/j.marpolbul.2010.09.009
  91. Costa, P.M.; Miguel, C.; Caeiro, S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "Transcriptomic analyses in a benthic fish exposed to contaminated estuarine sediments through laboratory and in situ bioassays". Ecotoxicology 20 8 (2011): 1749-1764. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054924869&partnerID=MN8TOARS.
    10.1007/s10646-011-0708-z
  92. Costa, P.M.; Neuparth, T.S.; Caeiro, S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "Assessment of the genotoxic potential of contaminated estuarine sediments in fish peripheral blood: Laboratory versus in situ studies". Environmental Research 111 1 (2011): 25-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-78751634455&partnerID=MN8TOARS.
    10.1016/j.envres.2010.09.011
  93. Costa, P.M.; Caeiro, S.; Diniz, M.S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "A description of chloride cell and kidney tubule alterations in the flatfish Solea senegalensis exposed to moderately contaminated sediments from the Sado estuary (Portugal)". Journal of Sea Research 64 4 (2010): 465-472. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957330202&partnerID=MN8TOARS.
    10.1016/j.seares.2010.01.005
  94. Lobo, J.; Costa, P.M.; Caeiro, S.; Martins, M.; Ferreira, A.M.; Caetano, M.; Cesário, R.; Vale, C.; Costa, M.H.. "Evaluation of the potential of the common cockle (cerastoderma edule l.) for the ecological risk assessment of estuarine sediments: Bioaccumulation and biomarkers". Ecotoxicology 19 8 (2010): 1496-1512. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952278633&partnerID=MN8TOARS.
    10.1007/s10646-010-0535-7
  95. Raimundo, J.; Costa, P.M.; Vale, C.; Costa, M.H.; Moura, I.. "DNA damage and metal accumulation in four tissues of feral Octopus vulgaris from two coastal areas in Portugal". Ecotoxicology and Environmental Safety 73 7 (2010): 1543-1547. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956995877&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2010.07.034
  96. Raimundo, J.; Costa, P.M.; Vale, C.; Costa, M.H.; Moura, I.. "Metallothioneins and trace elements in digestive gland, gills, kidney and gonads of Octopus vulgaris". Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 152 2 (2010): 139-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952741176&partnerID=MN8TOARS.
    10.1016/j.cbpc.2010.03.009
  97. Costa, P.M.; Chicano-Gálvez, E.; López Barea, J.; Delvalls, T.A.; Costa, M.H.. "Alterations to proteome and tissue recovery responses in fish liver caused by a short-term combination treatment with cadmium and benzo[a]pyrene". Environmental Pollution 158 10 (2010): 3338-3346. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958175613&partnerID=MN8TOARS.
    10.1016/j.envpol.2010.07.030
  98. Costa, P.M.; Santos, H.M.; Peres, I.; Costa, M.H.; Alves, S.; Capelo-Martinez, J.L.; Diniz, M.S.. "Toxicokinetics of waterborne trivalent arsenic in the freshwater bivalve corbicula fluminea". Archives of Environmental Contamination and Toxicology 57 2 (2009): 338-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651152876&partnerID=MN8TOARS.
    10.1007/s00244-008-9267-6
  99. Costa, P.M.; Caeiro, S.; Diniz, M.S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "Biochemical endpoints on juvenile Solea senegalensis exposed to estuarine sediments: The effect of contaminant mixtures on metallothionein and CYP1A induction". Ecotoxicology 18 8 (2009): 988-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349600930&partnerID=MN8TOARS.
    10.1007/s10646-009-0373-7
  100. Costa, P.M.; Diniz, M.S.; Caeiro, S.; Lobo, J.; Martins, M.; Ferreira, A.M.; Caetano, M.; et al. "Histological biomarkers in liver and gills of juvenile Solea senegalensis exposed to contaminated estuarine sediments: A weighted indices approach". Aquatic Toxicology 92 3 (2009): 202-212. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549150572&partnerID=MN8TOARS.
    10.1016/j.aquatox.2008.12.009
  101. Diniz, M.S.; Peres, I.; Castro, L.; Freitas, A.C.; Rocha-Santos, T.A.P.; Costa, P.M.; Pereira, R.; Duarte, A.C.. "Effects of ECF-Kraft pulp mill effluent treated with fungi (Rhizopus oryzae) on reproductive steroids and liver CYP1A of exposed goldfish (Carassius auratus)". Ecotoxicology 18 8 (2009): 1011-1017. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349601648&partnerID=MN8TOARS.
    10.1007/s10646-009-0392-4
  102. Costa, P.M.; Costa, M.H.. "Biochemical and histopathological endpoints of in vivo Cadmium toxicity in Sparus aurata | Respuestas bioquímicas e histopatológicas a la toxicidad por cadmio in vivo en Sparus aurata". Ciencias Marinas 34 3 (2008): 349-361. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949131742&partnerID=MN8TOARS.
    10.7773/cm.v34i3.1394
  103. Diniz, M.S.; Santos, H.M.; Costa, P.M.; Peres, I.; Costa, M.H.; Alves, S.; Capelo-Martinez, J.L.. "Effects of exposure to arsenic in Corbicula fluminea: Evaluation of the histological and histochemical and biochemical responses | Efectos de la exposición al arsénico en Corbicula fluminea: Evaluación de las respuestas histológicas, histoquímicas y bioquímicas". Ciencias Marinas 34 3 (2008): 307-316. http://www.scopus.com/inward/record.url?eid=2-s2.0-54849409211&partnerID=MN8TOARS.
    10.7773/cm.v34i3.1396
  104. Costa, P.M.; Lobo, J.; Caeiro, S.; Martins, M.; Ferreira, A.M.; Caetano, M.; Vale, C.; DelValls, T.A.; Costa, M.H.. "Genotoxic damage in Solea senegalensis exposed to sediments from the Sado Estuary (Portugal): Effects of metallic and organic contaminants". Mutation Research - Genetic Toxicology and Environmental Mutagenesis 654 1 (2008): 29-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-46849095100&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2008.04.007
  105. Costa, P.M.; Repolho, T.; Caeiro, S.; Diniz, M.E.; Moura, I.; Costa, M.H.. "Modelling metallothionein induction in the liver of Sparus aurata exposed to metal-contaminated sediments". Ecotoxicology and Environmental Safety 71 1 (2008): 117-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049104386&partnerID=MN8TOARS.
    10.1016/j.ecoenv.2007.05.012
  106. Santos, H.M.; Diniz, M.S.; Costa, P.M.; Peres, I.; Costa, M.H.; Alves, S.; Capelo, J.L.. "Toxicological effects and bioaccumulation in the freshwater clam (Corbicula fluminea) following exposure to trivalent arsenic". Environmental Toxicology 22 5 (2007): 502-509. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548754524&partnerID=MN8TOARS.
    10.1002/tox.20303
  107. Diniz, M.S.; Santos, H.M.; Costa, P.M.; Peres, I.; Costa, M.H.; Capelo, J.L.. "Metallothionein responses in the Asiatic clam (Corbicula fluminea) after exposure to trivalent arsenic". Biomarkers 12 6 (2007): 589-598. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748931459&partnerID=MN8TOARS.
    10.1080/13547500701507701
  108. Costa, P.M.; Costa, M.H.. "Genotoxicity assessment in fish peripheral blood: A method for a more efficient analysis of micronuclei". Journal of Fish Biology 71 SUPPL. A (2007): 148-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547103231&partnerID=MN8TOARS.
    10.1111/j.1095-8649.2007.01548.x
  109. Costa, P.M.. "First record of Diaphus dumerilli (Myctophiformes: Myctophidae) off the Portuguese mainland coast". Journal of Fish Biology 64 5 (2004): 1435-1438. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442686861&partnerID=MN8TOARS.
    10.1111/j.0022-1112.2004.00386.x
  110. Alagador, D.A.; Costa, P.M.. "Distribution patterns of deep-sea benthopelagic fish off the Algarve coast (Portugal)". Boletin - Instituto Espanol de Oceanografia 19 1-4 (2003): 407-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-26244443729&partnerID=MN8TOARS.
Capítulo de livro
  1. carolina madeira; Pedro M. Costa. Autor correspondente: Pedro M. Costa. "Proteomics in Systems Toxicology". In APCSB: Proteomics and systems biology, 55-91. Cambridge, Estados Unidos: Elsevier / Academic Press, 2021.
    Publicado • 10.1016/bs.apcsb.2021.03.001
  2. Costa, P.M.; Fadeel, B.. "Emerging Systems Toxicology Approaches in Nanosafety Assessment". In Nanotoxicology: Experimental and Computational Perspectives, editado por Dhawan, A.; Anderson, D.; Shanker , R., 174-202. Cambidge, Reino Unido: Royal Society of Chemistry, 2018.
    Publicado • 10.1039/9781782623922-00174
  3. Martins, M.; Costa, P.M.. "The Comet assay in aquatic (eco)genotoxicology using non-conventional model organisms: relevance, constraints and prospects". In Ecotoxicology and Genotoxicology: Non-traditional Aquatic, editado por Larramendy, N., 1-32. Cambridge, Reino Unido: Royal Society of Chemistry, 2017.
    Publicado
  4. Louro, H.; Pinto, M.; Vital, N.; Tavares, A.M.,; Costa, P.M.; Silva, M.J.. "The LacZ plasmid-based transgenic mouse model: an integrative approach to study the genotoxicity of nanomaterials". editado por Sierra, L.M.; Gaivão, I., 451-477. 2014.
    10.1007/978-1-4939-1068-7_25
Livro
  1. Costa, P.M.. The Handbook of Histopathological Practices in Aquatic Environments: Guide to Histology for Environmental Toxicology. 2017.
Poster em conferência
  1. Padrão, Inês; Cátia Gonçalves; António Pedro Alves de Matos; Roque, ACA; Costa, Pedro M.. "Detection and isolation of reflectins from the common octopus". Trabalho apresentado em 1st Egas Moniz One Health Symposium, 2022.
  2. Pedro M. Costa. "Drug Discovery from Cnidaria: Delivery, Bioreactivity and Molecular Characterization of Toxins from the Sea Anemone Actinia". Trabalho apresentado em One Health Symposium, 2022.
  3. Martins, Carla; Moutinho Cabral, Inês; L.M. Carvalho; M.F. de Oliveira Galvão; M.L. Saúde; K. Dreij; Costa, Pedro M.. "Molecular mechanisms behind the effects from interaction of carcinogens and emerging pollutants: in vivo and in vitro perspective". Trabalho apresentado em XVIth International Congress of Toxicology (ICT 2022), 2022.
  4. Pedro M. Costa. "An investigation on the biotechnological potential of the gastropod Nucella lapillus on the search for cysteine-rich toxins and others proteins". Trabalho apresentado em ICYMARE – International Conference for Young Marine Researchers, 2021.
  5. Pedro M. Costa. "The biotechnological potential of marine bio-reactives: exploring novel toxins from the Polychaeta Glycera alba". Trabalho apresentado em ICYMARE – International Conference for Young Marine Researchers, 2021.
  6. Pedro M. Costa. "Venomous weever fishes: a painful sting with biotechnological potential? A study on venom production, delivery and toxin characterization in Echiichthys vipera". Trabalho apresentado em ICYMARE – International Conference for Young Marine Researchers, Bremen (Germany), September 2021, 2021.
  7. Pedro M. Costa. "Multidisciplinary approach to porphyrin-like photosensitizing pigments from a marine polychaeta". Trabalho apresentado em XII European Conference on Marine Natural Products, 2021.
  8. Costa, Pedro M.. "Emerging marine bioproducts and blue biotechnology: exploring the potential of marine invertebrates". Trabalho apresentado em 42nd CIESM Congress, 2019.
  9. P.M. Costa. "Porphyrin pigments in Polychaeta: Explorations on the evolution of haem metabolism in marine eumetazoans". Trabalho apresentado em XVI International Symposium on Marine Natural Products | XI European Conference on Marine Natural Products, 2019.
  10. Pedro M. Costa. "Can trait evolution and phylogenetics predict the discovery of new toxins from marine invertebrates?". Trabalho apresentado em XVI International Symposium on Marine Natural Products | XI European Conference on Marine Natural Products, 2019.
  11. Pedro M. Costa. "Toxins from an unsuspected invertebrate: a poisonous cocktail from a jawless predatory polychaete". Trabalho apresentado em XVI International Symposium on Marine Natural Products | XI European Conference on Marine Natural Products, 2019.
  12. Pedro M. Costa. "Microanatomical and histochemical traits as biomarkers of toxin secretion in marine invertebrates". Trabalho apresentado em XVI International Symposium on Marine Natural Products | XI European Conference on Marine Natural Products, 2019.
  13. Pedro M. Costa. "Porphyrin pigments in Polychaeta: Explorations on the evolution of haem metabolism in marine eumetazoans". Trabalho apresentado em XVI International Symposium on Marine Natural Products | XI European Conference on Marine Natural Products, 2019.
  14. Pedro M. Costa. "The interaction effects of carcinogenic toxicants and emerging pollutants in zebrafish embryos: A toxicopathological and genotoxicological approach". Trabalho apresentado em Encontro Ciência 2019, 2019.
  15. Pedro M. Costa. "Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution". Trabalho apresentado em NANOCON 2018, 2018.
  16. Pedro M. Costa. "Unravelling warming sensitivity across fish coastal life-cycle stages: from cellular biology to ecological patterns". Trabalho apresentado em IMMR 2018, 2018.
  17. Pedro M. Costa. "Unravelling the mysteries of a marine Polychaeta: Connecting toxicity with fluorescence". Trabalho apresentado em Encontro Ciência 2018, 2018.
  18. Pedro M. Costa. "Caracterização química, molecular e toxicológica de uma nova biotoxina produzida por um poliqueta marinho: Eulalia viridis". Trabalho apresentado em I Congresso de Biologia Marinha, 2018.
  19. Pedro M. Costa. "The biotechnological value of a novel potent marine biotoxin from the polychaete worm Eulalia viridis: Chemical and toxicological evaluation". Trabalho apresentado em Encontro Ciência 2017, 2017.
  20. Pedro M. Costa. "Cytotoxicity assessment of a panel of surface-modified copper oxide nanoparticles in a murine monocyte-macrophage cell line (RAW264.7)". Trabalho apresentado em CompNanoTox 2015, 2015.
  21. Pedro M. Costa. "An application of fish gill histopathology to address the interaction effects between different polycyclic aromatic hydrocarbons (PAHs)". Trabalho apresentado em CICTA 2015, 2015.
  22. Pedro M. Costa. "Sparus aurata larvae sensitivity to global warming: oxidative stress responses". Trabalho apresentado em CLIMA 2014, 2014.
  23. Pedro M. Costa. "Impact of exposure to sea warming and acidification in Sparus aurata juveniles: oxidative stress responses". Trabalho apresentado em CLIMA 2014, 2014.
  24. Pedro M. Costa. "Analysis of the interaction of polycyclic aromatic compounds in a model organism: integration of genotoxic and histopathological effects". Trabalho apresentado em IMMR 2014, 2014.
  25. Pedro M. Costa. "Development of an integrative approach for the characterization of environmental risk on marine transition ecosystems: the Sado estuary as a case study". Trabalho apresentado em IMMR 2014, 2014.
  26. Pedro M. Costa. "Development of histopathological indices in sole (Solea solea) and hake (Merluccius merluccius) for the implementation of the European Marine Strategy Directive along the Basque continental shelf". Trabalho apresentado em ISOBAY 2014, 2014.
  27. Pedro M. Costa. "Histopathological effects of waterborne acrylamide in Mytilus galloprovincialis". Trabalho apresentado em SPMicros 2013, 2013.
  28. Pedro M. Costa. "Sea warming affects bream (Sparus aurata) tissues and stress proteins (HSP70)?". Trabalho apresentado em SPMicros 2012, 2012.
  29. Pedro M. Costa. "Statistical techniques for ecological risk assessment of estuarine sediments". Trabalho apresentado em ENBIS2011 Conference, 2011.
  30. Pedro M. Costa. "Cytotoxic and genotoxic assessment of potentially contaminated sediments from the Sado Estuary". Trabalho apresentado em 41st EEMS Meeting, 2011.
  31. Pedro M. Costa. "Selecting a rapid and sensitive battery of bioassays for ecotoxicological characterization of sediments: application to Sado Estuary, Portugal". Trabalho apresentado em 47th ECSA Symposium, 2010.
  32. Pedro M. Costa. "Impact of remobilized contaminants in Mytilus edulis during dredging operations in a harbour area: bioaccumulation and biomarker responses". Trabalho apresentado em 47th ECSA Symposium, 2010.
  33. Pedro M. Costa. "Evaluation of the potential of the common cockle for ecological risk assessment through depuration assays and biomarkers". Trabalho apresentado em 47th ECSA Symposium, 2010.
  34. Pedro M. Costa. "Genotoxicity in digestive gland of Octopus vulgaris collected in the Portuguese coast". Trabalho apresentado em 14th International Symposium on Toxicity assessment, 2009.
  35. Pedro M. Costa. "Biomarkers and bioaccumulation in Cerastoderma edule exposed to estuarine sediments". Trabalho apresentado em CICTA 2008, 2008.
  36. Pedro M. Costa. "Toxicity of waterborne cadmium on Solea senegalensis Kaup, 1858: biochemical and histopathological biomarkers". Trabalho apresentado em SETAC Annual Meeting 2007, 2007.
  37. Pedro M. Costa. "Biomarkers and bioaccumulation in Solea senegalensis exposed to sediments from the Sado Estuary (Portugal): an approach to a Sediment Risk Assessment strategy". Trabalho apresentado em SETAC Annual Meeting 2007, 2007.
  38. Pedro M. Costa. "Assessment of bioaccumulation and depuration in Corbicula fluminea Mühlfeld, 1844, after experimental exposure to arsenic". Trabalho apresentado em SETAC Annual Meeting 2007, 2007.
  39. Pedro M. Costa. "Impact of arsenic contamination on histological and biochemical responses in Corbicula fluminea Muhlfeld, 1844". Trabalho apresentado em XX encontro nacional da Sociedade Portuguesa de Química, 2006.
  40. Pedro M. Costa. "Histopatologia e genotoxicidade do cádmio em Sparus aurata L., 1758". Trabalho apresentado em XIII Seminário Ibérico de Química Marinha, 2006.
  41. Pedro M. Costa. "Efeitos da toxicidade do cobre em Carassius auratus L. 1758". Trabalho apresentado em II Congresso Ibérico de Ecologia, 2006.

Outros

Conjunto de dados
  1. Costa, Pedro M.. Whole-transcritptome dataset for Eulalia viridis (Gene expression Omnibus accession nº GSE143954). https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143954.
  2. Comparative transcriptomics between two potentially toxin-secreting marine annelids: Glycera alba and Hediste diversicolor. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196852.
  3. Moutinho Cabral, Inês; Madeira, Carolina; Grosso, Ana Rita; Costa, Pedro M.. Cysteine-rich venom protein from Glycera alba (Accession OL606744). GenBank.
  4. Moutinho Cabral, Inês; Madeira, Carolina; Grosso, Ana Rita; Costa, Pedro M.. Serine protease inhibitor Kazal-type from Glycera alba (Accession OL606745). GenBank.
  5. Moutinho Cabral, Inês; Madeira, Carolina; Grosso, Ana Rita; Costa, Pedro M.. Thyrostimulin beta-5 subunit from Hediste diversicolor (Accession OL606747). GenBank.
  6. Moutinho Cabral, Inês; Madeira, Carolina; Grosso, Ana Rita; Costa, Pedro M.. Whole-transcritptome dataset for Glycera alba and Hediste diversicolor (Accession GSE196852). Gene Expression Omnibus.
  7. Moutinho Cabral, Inês; Madeira, Carolina; Grosso, Ana Rita; Costa, Pedro M.. Cysteine-rich secretory protein from Hediste diversicolor (Accession OL606746). GenBank.
Outra produção
  1. On the progression of COVID19 in Portugal: A comparative analysis of active cases using non-linear regression. 2020. Ana Milhinhos; Pedro M. Costa. https://doi.org/10.1101/2020.05.02.20088856.
    10.1101/2020.05.02.20088856
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/07 From the biota to human health: New prospects for marine ecotoxicology Encontro Ciência 2023
Universidade de Aveiro (Aveiro, Portugal)
2023/04 A century of research on environmental carcinogens: From legacy to emerging pollutants II TOXRUN International Congress
Toxicology Research Unit – CESPU (Porto, Portugal)
2023/01/20 Novel tools and old problems Where do we stand after a century of research into environmental carcinogens
University of Córdoba (Campus de Rabanales) (Córdoba, Espanha)
2022/03/30 Marine Biotechnology: Applications in Sustainability and Medicine | PROSPECTS AND TOOLS FOR BIOPROSPECTING VII Semana da bioengenharia do IST
Instituto Superior Técnico da Universidade de Lisboa (Lisbon, Portugal)
2021/09 A study on whole-transcriptomes of two Polychaeta for discovering novel bioproducts with potential biotechnological applications ICYMARE – International Conference for Young Marine Researchers
(Kiel, Alemanha)
2021/08 A stinging issue: omics and computational tools for the bioprospecting of novel marine toxins XII European Conference on Marine Natural Products
(Galway, Irlanda)
2021/08 Localization and bioreactivity of cysteine-rich secretions in the marine gastropod Nucella lapillus XII European Conference on Marine Natural Products
(Galway, Irlanda)
2019/12/13 [INVITED] Bioprodutos marinhos e biotecnologia azul: Novos horizontes para a indústria, ciência e biomedicina. Jornadas do Mar 2020
Associação de Estudantes do Instituto de Ciências Abel Salazar (Porto, Portugal)
2019/09 Marine venoms and how to find them: predicting the discovery of new toxins from predatory Polychaeta along the tree of life ICYMARE – International Conference for Young Marine Researchers
(Bremen)
2019/07/08 [INVITED] Blue Economy: How can novel bioproducts push Marine Biotechnology into the path of sustainable growth? Encontro Ciência 2019
Centro de Congressos de Lisboa (Lisboa, Portugal)
2019/04/03 (INVITED] Toxins, poisons and venoms: How to turn noxious marine animals into biotechnological assets Ciclo de Conferências LAQV & UCIBIO
UCIBIO - Departamento de Química, FCT-NOVA (Portugal)
2018/09/29 [INVITED] Toxins and other bio-reactives from marine invertebrates: Hazards or novel resources? UCIBIO Annual Meeting 2018
UCIBIO - Applied Molecular Biosciences Unit (Monte de Caparica, Portugal)
2018/07 Environmental Risk of carcinogenic toxicants and emerging pollutants: Testing their interactions in vivo and in vitro IMMR 2018
MARE | IPL (Peniche, Portugal)
2018/07 The great biotechnological potential of a marine polychaete: An alliance between toxin and natural fluorescence IMMR 2018
MARE | IPL (Peniche, Portugal)
2018/06 New lessons from ancient life: Marine invertebrates as a source of new drugs 3rd International Congress of CiiEM
CiiEM / CESEM (Almada, Portugal)
2018/01 Estudo de caracterização de pigmentos de um poliqueta marinho, Eulalia viridis (L.): Contribuição para aplicações biotecnológicas I Congresso de Biologia Marinha
(Faro, Portugal)
2018/01 Relevância ecológica de uma nova toxina (Phyllotoxina) produzida pelo poliqueta Eulalia viridis: interacções predador-presa. I Congresso de Biologia Marinha
(Faro, Portugal)
2017/11/22 [INVITED] Metal and metal oxide nanomaterials: Applications, hazards and novel approaches to risk assessment Nanotoxicology and Micropollution
NANU - Núcleo de Nanotecnologia da FCT-NOVA (Monte de Caparica, Portugal)
2017/06 Microscopy as a tool in drug-discovery Marine Biotechnology: A marine annelid as case-study 2nd International Congress of CiiEM
CiiEM | CESEM (Almada, Portugal)
2017/05 Rapid filtering and ingestion of microplastics by marine mussels under ecologically-relevant scenarios SETAC Europe 27th Annual Meeting
SETAC Europe (Brussels, Bélgica)
2016/12 Ingestão de microplásticos por Mytilus galloprovincialis: análise histológica e respostas bioquímicas 1º Congresso Português sobre Microplásticos: Contaminação Ambiental por Microplásticos e suas implicações para a Saúde dos Ecossistemas, Animal e Humana
(Porto, Portugal)
2016/06 Short-term inhalation exposure to copper oxide nanoparticles induces gene expression changes associated with inflammation and cell proliferation in the rat bronchoalveolar epithelium 8th International Nanotoxicology Congress
(Boston, Estados Unidos)
2015/11/24 [INVITED] Advances in the structure of the Cephalopod digestive gland: On the microanatomy of a polyvalent organ Workshop on Digestive system in cephalopods
FA1301 COST Action (Cascais, Portugal)
2015/07 DNA damage and marine pollutants: mechanisms of toxicity, applications and handicaps of surveying genotoxicity in vivo in non-model organisms CICTA 2015
CICTA | UTAD (Vila Real, Portugal)
2015/07 Effects of carcinogenic versus non-carcinogenic Polycyclic Aromatic Hydrocarbons (PAHs) and their mixtures: an integrated biomarker survey CICTA 2015
CICTA | UTAD (Vila Real, Portugal)
2015/07 Interaction effects between metals and PAHs in the aquatic environment: An in vivo study on genotoxicity and DNA repair with the zebrafish model CICTA 2015
CICTA | UTAD (Vila Real, Portugal)
2015/05/27 [INVITED] New challenges and old problems: On a toxicologist’s perspective on environmental and human health Seminar on Toxicology
Institute for Environmental Medicine, The Karolinska Institute (Stockholm, Suécia)
2014/08/07 [INVITED] Dilution is (definitely) not the solution to pollution: tackling the stormy seas of Marine Environmental Toxicology Seminar on Environmental Toxicology
Department of Biology, Faculty of Mathematics and Natural Sciences, University of Bergen (Bergen, Noruega)
2014/07 A physiological study of integument secretions in the marine polychaete Eulalia viridis and their potential biotechnological value IMMR 2014
MARE | IPL (Peniche, Portugal)
2014/07 Exposure to contaminated sediments induces alterations in the gill epithelia in juvenile Solea senegalensis: a comparative in situ and ex situ study IMMR 2014
MARE | IPL (Peniche)
2014/05/12 [INVITED] Microscopy studies of marine invertebrates: from physiology and pathology to biotechnological applications Egas Moniz Symposium on Electron Microscopy
Egas Moniz, Cooperativa de Ensino CRL (CESEM) (Monte de Caparica, Portugal)
2014/05 Development of histopathological indices in digestive gland and gonad of mussels (M. galloprovincialis): effects of season and other potential confounding factors 54th ECSA Symposium
MARE (Sesimbra, Portugal)
2014/05 Environmental risk assessment in an impacted estuary: a decision-making framework 54th ECSA Symposium
MARE (Sesimbra, Portugal)
2014/05 Stress oxidative responses in gilthead seabream (Sparus aurata) juveniles as a result of sea warming and acidification 54th ECSA Symposium
MARE (Sesimbra, Portugal)
2014 Biochemical and physiological changes induced by thermal stress in juvenile Sparus aurata CLIMA 2014
(Aveiro, Portugal)
2013/12 Microanatomical alterations in the gut of a marine polychaete (Eulalia viridis, Errantia: Phyllodocidae) during the digestive process SPMicros 2013
(Lisbon, Portugal)
2013/11 Assessment of sediment contamination in an impacted estuary: differential effects and adaptations of sentinel organisms and implications for biomonitoring sedNet Conference 2013
SedNet (Lisboa, Portugal)
2013/11 Efeitos comparativos da exposição a sedimentos contaminados com PAHs cancerígenos e não cancerígenos em Dicentrarchus labrax: estudos histopatológicos 10ª Conferência Nacional do Ambiente
(Aveiro, Portugal)
2013/11 Efeitos toxicológicos de um fármaco, Sinvastatina, em Gammarus locusta: Avaliação histopatológica 10ª Conferência Nacional do Ambiente
(Aveiro, Portugal)
2013/11 Desregulação endócrina em linguados recolhidos numa zona estuarina: relação com os perfis de contaminação sedimentar 10ª Conferência Nacional do Ambiente
(Aveiro, Portugal)
2013/10/13 [INVITED] Effects on commercial species and the estuarine environment HERA project Public seminar – Environmental risk assessment of a contaminated estuarine environment: the Sado Estuary Case study
HERA project (Lisboa, Portugal)
2013/09 Comparing the genotoxic potential of carcinogenic and non-carcinogenic sediment-bound PAHs in fish peripheral blood ICOETox 2013
INSA (Porto, Portugal)
2013/09 Employment of the alkaline single-cell gel electrophoresis assay on tree cell cultures: protocol development and application ICAW 2013
INSA (Porto, Portugal)
2013/09 Can estuary sediment contaminants interfere with the DNA repair capacity of HepG2 cells ICAW 2013
INSA (Porto, Portugal)
2012/09 A microscopical study of the “chlorophylloid” pigment cells of the marine polychaete Eulalia viridis (L.) SPMicros 2012
(Lisbon, Portugal)
2012/06 Environmental risk assessment in an estuary affected by anthropogenic contamination: from ecological impacts to risk to human communities 50th ECSA Symposium
(Venice, Itália)
2012/05 Characterization of cytotoxic and genotoxic effects of contaminated sediments from the Sado estuary and potential human health risk ICEH 2012
(Lisbon, Portugal)
2012/05 Food frequency consumption in a fishing community from a contaminated estuarine environment. A case study ICEH 2012
(Lisbon, Portugal)
2012/01/13 [INVITED] Dyes and lies: histology and histochemistry in metal toxicology Workshop on toxicology of non–essential metals
CESAM / Universidade de Aveiro (Aveiro, Portugal)
2011/07 Surveying biomarker responses in invertebrates and vertebrates for Ecological Risk Assessment in a Portuguese estuarine area 5th EUROLAG
(Aveiro, Portugal)
2010/09 Can the integration of multiple effects and responses to toxicity with sediment geochemistry solve the complexity of sediment risk assessment? A study with a benthic fish to determine estuarine sediment ecological risk 47th ECSA Symposium
(Figueira da Foz, Portugal)
2010/09 Exploring parametric and non–parametric statistics as an integrative tool for the ecological risk assessment of estuarine sediments 47th ECSA Symposium
(Figueira da Foz, Portugal)
2009/09 Proteomics in Ecotoxicology: comparing in situ to laboratory assays using benthic fish for ecological risk assessment 14th International Symposium on Toxicity assessment
(Metz, França)
2009/09 Evaluation of the potential of translocated common cockle for ecological risk assessment studies: bioaccumulation and biomarkers test 14th International Symposium on Toxicity assessment
(Metz, França)
2008/11 Assessing chronic effects and responses to estuarine sediment contaminants in juvenile Solea senegalensis Kaup 1858 (Pleuronectiformes: Soleidae) 7th International Flatfish Symposium
(Sesimbra, Portugal)
2008/11 Pollution by endocrine disruptors: intersex in male Solea senegalensis collected in river Tagus estuary 7th International Flatfish Symposium
(Sesimbra, Portugal)
2008/03 Are tissue metal accumulation and cell–cycle turnover in wild Octopus vulgaris (Cuvier, 1799) prevailing factors in DNA damage? CICTA 2008
(Lisbon, Portugal)
2008/03 Toxicological effects in Solea senegalensis exposed to estuarine sediments: an integrative approach to sediment risk assessment CICTA 2008
(Lisbon, Portugal)
2007/11 Ecotoxicological studies in the freshwater clam (Corbicula fluminea) exposed to trivalent arsenic Congresso Português de Malacologia
(Lisboa, Portugal)
2006/09 Efeitos da exposição prolongada a arsénio sobre Corbicula fluminea Mühlfeld, 1844: Avaliação das respostas histológicas e histoquímicas e bioquímicas XIII Seminário Ibérico de Química Marinha
(Lisbon, Portugal)
2006/07 Quantificação de metalotionina no fígado de Sparus aurata L., 1758. Perciformes: Sparidae) II Congresso Ibérico de Ecologia
(Lisbon, Portugal)
2006/06 Utilização de Corbicula fluminea Mühlfeld, 1844,como indicador de contaminação por arsénio: avaliação da capacidade de resposta através da determinação de metalotioninas e arsénio nos tecidos III Simpósio Ibérico da bacia hidrográfica do Rio Minho
(Vila Nova da Cerveira, Portugal)
2006/02 Arsenic Bioremediation Technology COhiTEC
Faculdade de Economia da Universidade Nova de Lisboa (Lisbon, Portugal)
2002/10 Distribution patterns of deep–sea benthopelagic fish off the Algarve coast, Portugal XII Simpósio Ibérico de Estudos do Bentos Marinho
(La Línea de la Concepción, Espanha)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2024/01/01 - Atual Integrated approach to harness the biotechnological potential from cephalopods
Coorientador de Catarina Faurtino
Doctoral Programme in Biotechnology (Doutoramento)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/09/01 - Atual Variation of venom composition and toxicity in weever fishes (Trachinidae). Implications for biomedicine and biotechnology
Orientador de Samuel Pereira
Master Programme in Molecular Genetics and Biomedicine (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/09/01 - Atual Evolution of the minimal stress proteome in marine fauna: potential for adaptation to climate change
Orientador de Raquel Maricato Teixeira
Master in Computational Biology and Bioinformatics (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/09/01 - Atual Multilayer molecular networks shaping goby fish physiological responses to marine heatwaves in intertidal habitats
Orientador
Master in Computational Biology and Bioinformatics (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/09/01 - Atual Multi-omics approach to unravel phenotypic responses of tropical fish from the Eastern Tropical Pacific to ocean warming and acidification scenarios
Coorientador de David Lohmann
Master in Computational Biology and Bioinformatics (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/05 - Atual Unveiling the molecular and cellular mechanisms underlying the regeneration blastema in marine annelids
Orientador de Inês Moutinho Cabral
Doctoral Programme in Biology
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/03 - Atual Physiological, metabolic, and molecular responses of the ditch shrimp Palaemon varians to multiple global change drivers across latitude, different life stages and sex
Coorientador de Madalena Duarte Missionário
Doctoral Programme in Biology (Doutoramento)
Universidade de Aveiro, Portugal
2023/02 - Atual Drug discovery from novel marine compounds: Bioactivity testing of cephalopod venoms
Orientador de Maria Trindade Rodrigues Gomes Do Paço
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2023/01/10 - Atual Quantification and characterization of pigments present in echinoderms from bottom trawl fishery discards
Orientador de David Leitão Silva
Master Programme in Biotechnology (Doutoramento)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/09 - Atual Cell-based ecotoxicological assessment of anthraquinone dyes
Orientador de Leonor Mateus de Araújo e Mello Loureiro
Undergraduate Programme in Cell and Molecular Biology (Licenciatura/Bacharelato)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02 - Atual Immunolocalisation of cell cycle regulators in zebrafish exposed to pollutant mixtures
Orientador de Eduardo Almeida
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/09 - Atual Tetrapyrrolic pigments from marine annelids as photosensitizers in photodynamic anti-cancer therapies
Orientador de Mariana Mendão
Master Programme in Biotechnology (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/07/01 - Atual Development of biobased and sustainable materials from polar cephalopods
Coorientador de Inês Padrão
Biotechnology (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/09 - Atual Identification, expression and toxicity assessment of the main venom components of weever fishes (Trachinidae): Variation with sex, age and size
Orientador de Telma Luís
Master Programme in Biotechnology (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 - Atual Coleoid venoms: Predicting cephalotoxin function and biotechnological applications from ecological and evolutionary traits
Orientador de Cátia Gonçalves
Biotechnology (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universitetet i Bergen Institutt for Biologi, Noruega
2017 - 2023/12 Carcinogenic toxicants and emerging pollutants. A comprehensive case-study on toxicant interactions in vivo and in vitro: from Molecular Toxicology to Environmental Risk Assessment
Orientador de Carla Martins
Environmental Science (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

The Karolinska Institute, Institute of Environmental Medicine, Suécia
2022/09 - 2023/11/16 Marine bioprospecting for drug discovery: Exploring novel toxin-derived bioactives from venomous annelids
Orientador de Catarina Faustino
Master Programme in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/09 - 2023/10/24 Characterisation of phase I genes from invertebrate detoxification mechanisms: the Mytilus sp. case-study
Orientador de João Vitorino
Master Programme in Molecular Genetics and Biomedicine (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2021/09 - 2022/12 Biotechnological potential of toxins from the anemone Actinia: Delivery, bioreactivity and molecular characterisation of actinoporins
Orientador de Maria Alcaide
M.Sc. in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/09 - 2022/11 Gene networks and epigenetic regulators modulating heat adaptation in sand gobies: influence of seasonal environment and climate extremes in thermal tolerance
Coorientador de Miguel Nunes
Master Programme in Biotechnology (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/09 - 2022/11 Geração e caracterização de linhas transgénicas de peixe-zebra para o estudo da estrutura e funcionamento do cérebro de vertebrados
Coorientador de Inês Gonçalves
Master Programme in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02 - 2022/06 A microscopical exploration of the venom delivery system of the marine annelid Glycera alba
Orientador de Marta Silva
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02 - 2022/06 Goby fish stress responses in a multi-stressor environment: multigenerational effects of temperature and acidification
Orientador de Carolina Vares
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02 - 2022/06 Histological and histochemical detection of thermal stress-induced changes in vital organs of the marine fish Pomatoschistus microps
Coorientador de Beatriz Guerreiro
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/09 - 2022/01/25 The biotechnological potential of marine bio-reactives: Isolation and characterization of novel toxins from Polychaeta
Orientador de Sónia Campos
Master Programme in Biotechnology (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/09 - 2022/01/25 Expression and characterisation of cysteine-rich secretory proteins in a marine gastropod
Orientador de Marta Gato
Master Programme in Biochemistry (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/09 - 2022/01/12 A computational approach to identify target receptors of marine toxins in the human proteome: Potential biotechnological applications
Orientador de Inês Cabral
M.Sc. in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02 - 2021/06 Toxicological screening for neurotoxic bioreactives from marine annelids
Orientador de Tiago Cardoso
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02 - 2021/06 Expression and identification of matrix-directed enzymes in cephalopod venoms
Orientador de Diogo Fonseca
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02 - 2021/06 A biomarker approach to undertanding the effects of ocean warming in a coastal fish (Gobiusculus flavescens)
Orientador de Beatriz Jesus
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02 - 2021/06 Analysis of the expression of venom components in Octopus vulgaris
Orientador de Francisca Silva
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/09 - 2021/02 The biotechnological value of a novel potent marine biotoxin from the polychaete worm Eulalia viridis: chemical and toxicological evaluation
Orientador de Ana P. Rodrigo
Environmental Science (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09 - 2021/01 A transcriptomic approach to the metabolism of porphyrin-like pigments in a marine Polychaeta (Eulalia sp.)
Orientador de Leonor Santos
M.Sc. in Molecular Genetics and Biomedicine
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09 - 2021/01 A molecular and pathophysiological approach to tissue regeneration in the planarian model
Orientador de Márcia Grou
M.Sc. in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09 - 2021/01 Novel developments on the association of the AHR-CYP1A1 axis and arterial hypertension related to obstructive sleep apnea
Coorientador de António Pimpão
M.Sc. in Molecular Genetics and Biomedicine (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2020/02 - 2020/07 Isolation and molecular characterisation of novel fluorescent proteins from the marine annelid Eulalia
Orientador de Ricardo Pereira
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/02 - 2020/07 CRISP-like toxins in a marine annelid: Molecular characterisation, expression and phylogeny
Orientador de Rita Bastos
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/02 - 2020/07 Bio-reactivity and toxicity testing of putative toxins from marine Polychaeta
Orientador de Íris Ramos
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/02 - 2020/07 Assaying toxicity and photodynamic properties of porphyrinoid pigments from marine invertebrates
Orientador de Ricardo Estevens
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02 - 2019/05 Toxin secretion in the gastropod Nucella: Delivery and primary toxicological effects
Orientador de Maria Rodrigues
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02 - 2019/05 Toxicity testing of porphyrinoid pigments from the marine annelid Eulalia
Orientador de Ana Catarina Santos
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02 - 2019/05 Detection and localisation of cysteine-rich secretions in a marine gastropod. Implications for toxin harvesting
Orientador de Mariana Calmão
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02 - 2019/05 Detection and localisation of cysteine-rich secretions in a marine gastropod. Implications for toxin harvesting
Orientador de Raquel Costa
Undergraduate Programme in Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/02 - 2019/03 Identifying hydrocarbon-detoxifying genes in a bivalve employed in marine biomonitoring
Orientador de Miguel L. Cunha
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/02 - 2018/05 Detecção e identificação de microorganismos num poliqueta marinho de interesse biotecnológico
Orientador de Luís Tanoeiro
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/02 - 2018/05 Caracterização fotoquímica das mucotoxinas de um poliqueta: Isolamento in vitro e ex vivo de novos fluorocromos
Orientador de Ana Rita Lopes
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/02 - 2018/05 Investigação sobre novas toxinas num gastrópode marinho predador de bivalves: Modo de secreção e função ecológica
Orientador de Miriam Casaca
Undergraduate Programme in Cell and Molecular Biology (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/09 - 2017/11 Addressing the effects of short-term exposure to TiO2 nanoparticles in fish gills: An ex-vivo approach
Orientador de Mattia Silva
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - 2017 Comparing pathological effects of microplastic ingestion between fish and crustaceans from rocky shores
Orientador de Ana Mota
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/09 - 2015/11 Interaction effects between metals and PAHs in the aquatic environment: An in vivo study on genotoxicity and DNA repair with the zebrafish model
Orientador de Ana Silva
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/09 - 2014/11 Analysis of the interaction of polycyclic aromatic hydrocarbons in a model organism: integrating genotoxic and histopathological effects
Orientador de Sofia Pereira
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/09 - 2014/11 Development of an integrative approach to environmental risk assessment in transitional marine ecosystems: the Sado Estuary as a case study
Orientador de Filipa Pereira
M.Sc. In Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2010 - 2014 Toxicity of carcinogenic and non-carcinogenic Polycyclic Aromatic Hydrocarbons and their mixtures to aquatic organisms under ecologically-relevant scenarios
Coorientador de Marta Martins
Environmental Science (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/09 - 2013/11 Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation
Orientador de Carla Martins
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012/09 - 2013/11 Can the complex mixture of sediment contaminants cause endocrine disruption on a benthic fish? A case study with Solea senegalensis
Coorientador de Cátia Gonçalves
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/09 - 2012/11 Integration of sediment contamination with multi–biomarker responses in a novel bioindicator candidate (Sepia officinalis) for risk assessment in impacted estuaries
Coorientador de Ana P. Rodrigo
M.Sc. in Environmental Engineering (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2019/06/17 - 2019/06/17 First UCIBIO Workshop on Blue Biotechnology (2019/06/17 - 2019/06/17)
Oficina (workshop) (Membro da Comissão Organizadora)
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2008/03/10 - 2008/03/12 CICTA 2008 Conference (Lisboa) (2008/03/10 - 2008/03/12)
Conferência (Membro da Comissão Organizadora)
IMAR - Instituto do Mar, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2019 - Atual 'Ciência Viva' Research internships for high-school students (two students per year)
Outro
Estágios Ciência Viva
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2024/01 - 2024/01 Workshop: Transcriptome assembly
Oficina (workshop)
2nd Course on computational Biosciences using HPC systems
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal

Infraestrutura Nacional de Computação Distribuída, Portugal
2023/09 - 2023/09 Lecture: Omics approaches and computational biology to predict sensitivity and resilience to ocean warming: Time to expand beyond the sum of effects?
Seminário
Summer school on climate-smart aquaculture and marine conservation: Molecular approaches to predict and improve fish performance under global change
Instituto Português do Mar e da Atmosfera, Portugal

UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/07 - 2023/07 Workshop: Introdução à histologia e microscopia
Oficina (workshop)
NOVA Summer School 2023
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/07 - 2023/07 Workshop: Microscopia e Histologia
Oficina (workshop)
Universidade de Verão em Biologia Celular e Molecular
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/09 - 2022/09 Workshop: Transcriptome assembly
Oficina (workshop)
Course on computational Biosciences using HPC systems
UCIBIO - Applied Molecular Biosciences Unit | Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal

Infraestrutura Nacional de Computação Distribuída, Portugal
2022/03/12 - 2022/03/12 Workshop: An introduction to biostatistics and R programming (hands-on session)
Oficina (workshop)
NBCM Workshop on Computational Biology
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/02/18 - 2022/02/18 Workshop on model animal histology (hands-on lab session)
Oficina (workshop)
JorTec Bioquímica 2022
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023/12/05 Extratos marinhos e de Voacanga africana como agentes anticancerígenos
Arguente principal
Helena Figueiredo (Mestrado)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2023/02/14 Biomonitoring Atlantic deepwaters through the assessment of biomarkers in sharks
Arguente principal
Luís Miguel Fonseca Alves (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
2022/07/28 Estudios ómicos del efecto de contaminantes emergentes en ecosistemas costeros: del laboratorio al campo.
Arguente
Ana María Herruzo Ruiz (Doutoramento)
Universidad de Córdoba, Espanha
2022/06/21 Desenvolvimento de ensaios de toxicidade crônica utilizando o crustáceo marinho Parhyale hawaiensis
Arguente
Amanda dos Santos (Doutoramento)
Universidade de São Paulo Faculdade de Ciências Farmacêuticas, Brasil
2022/02/02 Exploiting DNA UV-Vis radiation damage enhanced by nanoparticles
Arguente
Telma Marques (Doutoramento)
NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/20 Polyurethane-poly(ethylene glycol) hydrogels for tissue engineering applications
Presidente do júri
Inês Correia (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/20 Restoring NKX6-2 function by protein complementation: a proof-of-concept
Presidente do júri
Pedro Peralta (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/19 Tackling metastasis with gold nanoparticles: Inhibition of intercellular communication mediated by cancer cells-derived exosomes
Presidente do júri
António Carvalho (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/19 Caracterização da composição de exossomas excretados a partir de modelos celulares 2D e 3D derivados de células de carcinoma colorretal sensíveis ou resistentes à doxorrubicina
Presidente do júri
André Luz (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/18 Unravelling the role of neutrophils during spinal cord regeneration in zebrafish
Presidente do júri
Leonor Lameira (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/17 Novas estratégias para combater a resistência a múltiplos fármacos na leucemia mieloide crónica
Arguente principal
Patrícia Rodrigues (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/17 Exploring the effects of altered glycosylation on the immune response
Presidente do júri
João Rabaça (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022/01/17 Optimization of in vivo electroporation and comparison to microinjection as delivery methods for transgenesis in zebrafish (Danio rerio). Generation of a new neuronal zebrafish line
Presidente do júri
Inês Almeida (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2022 iPS cell modeling of choroideremia disease: insights into trafficking pathways and necroptosis
Presidente do júri
Daniela Colaço de Oliveira (Mestrado)
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
2021/02/22 Nanoconjugados para Gene Silencing
Arguente principal
David Filipe Salgueiro Pires (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/02/17 Combinação de lipossomas e nanopartículas de ouro para silenciamento génico
Arguente principal
David José Fonseca Fontinha (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/01/24 A "biomarker+histopathology" toolbox in Solea spp. for the assessment of the biological effects of pollution in the context of the EU Marine Strategy Framework Directive
Arguente
Tifanie Briaudeau (Doutoramento)
Universidad del País Vasco, Espanha
2017 Histopathological evaluation of two Blennius fishes exposed to microplastics via feeding
Arguente principal
Diogo Almeida (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 Determinação da concentração de mercúrio, e outros elementos traço, em tecidos de peixe-zebra (Danio rerio)
Arguente principal
Maria Pia Vaz do Rego Pacheco Silva (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/09 Integrated assessment of environmental pollution using diverse sentinel organisms within Basque marine environments
Arguente
Nagore Cuevas Suazo (Doutoramento)
Universidad del País Vasco, Espanha
2013 Comparative effects of sediments contaminated by carcinogenic and non–carcinogenic PAHs in Dicentrarchus labrax: a semi–quantitative histopathological approach
Arguente principal
José M. Santos (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013 Ética ambiental aplicada ao sector das pescas
Arguente principal
Luís M. Rodrigues (Mestrado)
Universidade Aberta, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2021/02 - Atual Frontiers in Marine Science (2296-7745) Frontiers Media
2018/08 - Atual International Journal of Environmental Research and Public Health (1660-4601) MDPI
2014/04/01 - Atual Ecotoxicology (1573-3017) Springer-Nature

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2023/12 - 2023/12 External reviewer for : FRG24 Comprehensive Projects (American University of Sharjah, United Arab Emirates )
Avaliador
American University of Sharjah, Emiratos Árabes Unidos
2022 - 2022 External Reviewer for FWF Einzelprojektes (Austrian Science Fund)
Avaliador
2020 - 2020 External reviewer for HFSP 2021 Research Grant Awards (Human Frontier Science Program Organization)
Avaliador
2019 - 2019 External reviewer for HFSP 2020 Research Grant Awards (Human Frontier Science Program Organization)
Avaliador
2017 - 2017 External Reviewer for FWF Einzelprojektes (Austrian Science Fund)
Avaliador
2015 - 2015 External reviewer for SASPRO grants (Slovak Academy of Sciences)
Avaliador
2014 - 2014 External reviewer for the PICT2013 grants (ANPCyT, Argentina)
Avaliador
2011 - 2011 External reviewer for PICT2011 grants (ANPCyT, Argentina)
Avaliador

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023 - Atual Introduction to Molecular Genetics Undergraduate Programme in Chemical and Biological Engineering (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/03 - Atual Biotechnology Undergraduate Programme in Cell and Molecular Biology (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/03 - Atual Molecular Biology B Undergraduate Programme in Biochemistry Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 - Atual Bioinformatics in Biomedicine M.Sc. in Molecular Genetics and Biomedicine (Mestrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 - Atual Cellular and Molecular Toxicology Undergraduate Programme in Cell and Molecular Biology (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09 - Atual Molecular Genetics A Undergraduate Programme in Cell and Molecular Biology (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - Atual Molecular Genetics B Undergraduate Programme in Biochemistry (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - Atual Biology Laboratory Techniques I Undergraduate Programme in Cell and Molecular Biology (Licenciatura) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - 2016 Application of Methods in Toxicological Research Toxicology (Master) Karolinska Institutet Institutet för miljömedicin, Suécia

Membro de associação

Nome da associação Tipo de participação
2012 - Atual Sociedade Portuguesa de Microscopia

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021/04 - Atual Scientific Committee of the Master Programme in Molecular Genetics and Biomedicine
Membro
Department of Life Sciences, NOVA School of Science and Technology, NOVA University of Lisbon, Portugal
Distinções

Prémio

2023 Best professor Award 2022: Department of Life Sciences
AEFCT, NOVA School of Science And Technology, NOVA University of Lisbon, Portugal
2021 Best professor Award 2020: Department of Life Sciences
AEFCT, NOVA School of Science And Technology, NOVA University of Lisbon, Portugal
2019 Publons top reviewers in Environment and Ecology and related (2017-2019)
Clarivate Analytics Inc, Estados Unidos
2008 CICTA 2008 Young Scientist Award - Best Platform (oral) Presentation

Outra distinção

2023 Top 2% most influential researchers worldwide ('Updated science-wide author databases of standardized citation indicators’)
2021 Journal (Toxins) Frontcover Article
Multidisciplinary Digital Publishing Institute AG, Suiça
2021 Journal (Marine Drugs) Highlighted Article
Multidisciplinary Digital Publishing Institute AG, Suiça
2015 Journal (Microscopy and Microanalysis) Frontcover Article
Cambridge University Press, Reino Unido