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Flávio Reis holds a PhD in Biomedical Sciences (2006) from the Faculty of Medicine of the University of Coimbra (FMUC), where he is Principal Investigator and Leader of the Group "Insulin resistance and diabetic angiopathy" at the Coimbra Institute for Clinical and Biomedical Research (iCBR). He is also group leader at the Center for Innovative Biomedicine and Biotechnology (CIBB), a UC biomedical research consortium formed by iCBR and Center for Neuroscience and Cell Biology (CNC). Flávio Reis is currently the coordinator of the Research Management Office at FMUC and held several other functions and positions, including in the UC Senate, in the FMUC Directive Council, in the Scientific Council of the Interdisciplinary Research Institute and in the Scientific Council of CIBB, both from UC. His scientific interests lie mainly in the field of therapeutic and nutraceutical interventions targeting cardiometabolic and renal diseases, including prediabetes, diabetes and its vascular complications (namely nephropathy), among other parallel interests. He has been working with animal models for more than 25 years and, considering the vast experience in this area, he is linked in various ways to Laboratory Animal Sciences (LAS). Actually, he: i) was president of the iCBR Animal Welfare Body (AWB) and is member of two other AWBs; ii) was chair of the organizing committee of the “3rd Nacional Symposium of AWBs: 3Rs in action”, held in Coimbra in 2018; iii) was the coordinator of the animal facility of iCBR; iv) is the coordinator of the Advanced Course on Animal Experimentation of the Doctoral Program in Health Sciences from FMUC; v) is member of the Executive Board of the Portuguese Society of Laboratory Animals Sciences (SPCAL) since 2021; vi) was chair of the organizing committee of the “5th SPCAL Congress: LAS for all”, held in Coimbra in 2024. Beyond preclinical research mainly involving animal models of disease, Flávio Reis has also been involved in multidisciplinary societal projects, developed in a perspective of co-creation with and for the community, involving different stakeholders, including patients, caregivers, entrepreneurs, among others. These projects aim to promote, integrate and support health literacy, namely toward healthy lifestyles. He coordinated and/or participated in about 60 projects, the majority of them with competitive funding and many supported by international agencies (EIT-Health, Erasmus Plus, Excellence Hubs, as examples), with a global amount for his Lab. work of more than 1.5 million euros. He was/is supervisor of about 130 students, including 4 postdocs, 20 PhD, 55 Master and 17 Degree, and participated in many PhD (47) and Masters (85) theses’ juris. He is (co)author of 167 full-papers published in international peer-reviewed journals, with more than 6,000 citations and an H index of 41, as well as editor of 2 international books and (co)author of 18 book chapters. He is also (co)author of other almost 220 publications (full-papers, proceedings and abstracts) published in international and national journals, as well as (co)author of more than 500 communications (as oral or poster presentation) in scientific meetings and was more than 30 times invited as speaker. He received 61 scientific merit awards. Flávio Reis is member of several national and international scientific societies and is/was Vice-President of the Portuguese Society of Pharmacology, of the Portuguese Society of Atherosclerosis and of the Portuguese Society of Hemorrheology and Microcirculation. He is a regular reviewer on evaluation panels for competitive funding in international research agencies (from UK, France, Italy, Switzerland, Austria and Chile), was reviewer of about 240 full-papers for more than 150 journals and is member of the Editorial Board of some. Flávio Reis is frequently involved in activities of dissemination and science communication to different target audiences of civil society, from young people to seniors.
Identificação

Identificação pessoal

Nome completo
Flávio Nelson Fernandes Reis

Nomes de citação

  • Reis, F

Identificadores de autor

Ciência ID
1C1D-1326-C311
ORCID iD
0000-0003-3401-9554

Endereços de correio eletrónico

  • freis@fmed.uc.pt (Profissional)

Moradas

  • Faculdade Medicina - Universidade de Coimbra. Sub-Unidade 1 - Polo 3 - Azinhaga de Santa Comba - Celas , 3000-548, Coimbra, Coimbra, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador proficiente (C1)
Formação
Grau Classificação
2021 - 2021
Concluído
Biomedical Sciences (Título de Agregado)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Maximal classification by unanimity
2006
Concluído
Biomedical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Vascular and platelet mechanisms in cyclosporin A-induced hypertension - Prevention using an NO donor - Isossorbide 5-Mononitrate" (TESE/DISSERTAÇÃO)
Approved by Distinction and Honour by Unanimity (A
2000
Concluído
Cellular and Molecular Biology (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Cyclosporin A effects on platelet reactivity in an experimental animal model (Efeitos da ciclosporina A na reactividade plaquetar num modelo animal experimental)" (TESE/DISSERTAÇÃO)
Excelent - unanimity (Muito Bom por Unanimidade)
1995
Concluído
Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2016/11/11 - Atual Investigador principal (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
2010/09/14 - 2016/11/10 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2005/12/01 - 2010/09/13 Assistente (Docente Universitário) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento
Empregador
1998 - 2006 Técnico Superior (Técnico Superior) Universidade de Coimbra Faculdade de Medicina, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2022/02/09 - Atual Vice-Presidente Sociedade Portuguesa de Farmacologia, Portugal
2021/04/01 - Atual Member of Directive Board Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2020/01/01 - Atual Member of the Scientific Council CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
2020 - Atual Leader of the Group "Insulin resistance and diabetic angiopathy" at iCBR|FMUC and at CIBB Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - Atual Vice-Presidente Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2016/01/02 - Atual Coordinator of the Research Management Office - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - 2023 Vice-Presidente Sociedade Portuguesa de Aterosclerose, Portugal
2018/03/01 - 2020 President of the Animal Welfare Body (ORBEA) of iCBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2018/01/01 - 2020 Coordinator of the Animal Facility of iCBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2011/01/01 - 2018 Coordinator of the Laboratory of Animal Behavior and Research - ICBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2017/07/01 - Atual Member (and Secretary) of the Assembly of FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2013/01/01 - Atual Member of Animal Welfare Body (ORBEA) of CNC/FMUC Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/01/01 - 2020/01/27 Member of the Scientific Council - Institute of Interdisciplinary Research (UC) Institute of Interdisciplinary Research (Instituto Interdisciplinar de Investigação: 3Is-UC) University of Coimbra, Portugal
2018/01/01 - 2020 Member of the Coordination Group for the Preparation of the Strategic Planning of FMUC 2019/2024. Universidade de Coimbra Faculdade de Medicina, Portugal
2017/03/01 - 2018 Management Commission of Animal Facility of IBILI (now iCBR) - FMUC Instituto Biomédico de Investigação Luz e Imagem (IBILI) - Faculdade de Medicina de Coimbra, Portugal
2004 - 2015 Evaluation Council (SIADAP) for FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2005 - 2007 Member of the Directive Council - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2005 - 2006 Member of Coimbra University Senade Universidade de Coimbra, Portugal
2004 - 2006 Member of the Assembly of Representatives - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
1996 - 1998 Monitor in a European Pharmacovigilance Research Group - Pancreatitis Study European Pharmacovigilance Research Group , Reino Unido
Projetos

Bolsa

Designação Financiadores
2019 - 2020 INOV C 2020 – IGNITION GRANT - The therapeutic potential of senescent leaves of Vaccinium corymbosum L. (blueberry) in Multiple Sclerosis: enhancement of a regional agricultural by-product
SAAC - CENTRO-46-2016-01 - #5625
Investigador responsável
Em curso
2018 - 2019 Functional assessment of the immune system in the tumor microenvironment and at the peripheral level in patients with bladder cancer
Jaba Recordati 2018
Investigador
Concluído
2017 - 2018 Follow-up of patients undergoing laparoscopic gastric band surgery: Characterization of traditional and emerging lipid profile biomarkers
FULAGB/LPB_CESPU_2017
Investigador
CESPU - Cooperativa de Ensino Superior Politécnico e Universitário CRL
Concluído
2017 - 2018 Regulation of renal and extra-renal erythropoietin gene expression in anemia induced by chronic renal failure and by acute hypoxia
165
Investigador
Banco Santander Totta - FMUC
Concluído
2017 - 2018 Interaction between intestinal microbiota and metabolic dysregulation in prediabetes - Impact of blueberries as a nutraceutical intervention
Emílio Peres 2017
Investigador responsável
Concluído
2016 - 2017 Association of dysfunction HDL with PCSK9 mutations and protein levels in myocardial infarction patients
167
Investigador responsável
Banco Santander Totta - FMUC
Concluído
2016 - 2017 Unraveling biomarkers of early and asymptomatic cardiac and hepatic changes in prediabetes
GIFT 2016
Investigador responsável
Concluído
2015 - 2016 Neuropeptide Y, Y1 receptor and dipeptidyl-peptidase 4: study of the interactions promoting remyelination in an animal model of multiple sclerosis
Biogen Idec Portugal
Investigador responsável
Concluído
2014 - 2015 NK cell-based adoptive therapy targeting human bladder cancer stem cells: impact on tumor progression using an humanized orthotopic animal model
Uro-Oncology Grant 2013
Investigador
Astellas European Foundation, Reino Unido
Concluído
2013 - 2014 Natural Killer-cell based immunotherapy targeting human bladder cancer stem cells
GAI-FMUC-2013
Investigador
Concluído
2013 - 2013 Cytoprotective action of insulin on heart and hippocampus from type 1 versus type 2 diabetes animal models
Investigador responsável
Sociedade Portuguesa de Diabetologia
Concluído
2012 - 2013 Strategies for ischemic conditioning in renal transplantation - usefulness in marginal grafts
Bolsa Astellas SPOT/APU 2012
Investigador
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia
Concluído
2012 - 2013 ROLE OF NK CELLS IN TUMORIGENESIS AND THERAPY RESPONSE OF BLADDER CANCER USING A HUMANIZED CSC-BASED ANIMAL MODEL
APU 2011
Investigador
Concluído
2012 - 2013 Role of NK Cells in tumorigenesis and therapy response of bladder cancer using a humanized CSC-based animal model
APU 2012
Associação Portuguesa de Urologia
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa Esperança, Vida e Solidariedade Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2009 - 2010 Bladder tumors - cytogenetic characterization and pharmacological investigation in cell cultures
Jaba Recordati 2009
Investigador
Associação Portuguesa de Urologia | Jaba Recordati
Concluído
2008 - 2009 Bladder tumors - clinical study of prognostic factors and prevention and experimental pharmacological treatment
APU 2018
Investigador
Concluído
2008 - 2009 Bladder tumors - clinical study of prognostic factors and prevention and experimental pharmacological treatment
APU 2008
Associação Portuguesa de Urologia
2007 - 2008 Study of the effectiveness of gliptins in prevention of pancreatic injury in an experimental model of diabetes mellitus type 2 - ZDF rat
Merk Sharp & Dohme
Investigador
Concluído
2004 - 2005 Experimental model of bladder carcinoma and evaluation of pharmacological efficacy preventive and curative
APU | JABA 2004
Investigador
Associação Portuguesa de Urologia - Jaba Recordati
Concluído

Projeto

Designação Financiadores
2022/01/01 - Atual CoLab HEALTHYAGEING@LAB
HEALTHYAGEING@LAB
Investigador
Universidade de Coimbra, Portugal
FCT - Fundação para a Ciência e Teconologia | COMPETE
Em curso
2018/07 - Atual DIAL4LIFE - Dialysis membranes by design: targeting neutrophil elastase to reduce inflammation/oxidative stress in end-stage renal disease
PT2020-SAICT-PTDC/ICDT-031322
PTDC/MEC-CAR/31322/2017
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - Atual PHENOLIVA - Contribution of olive and olive oil polyphenolic compounds to the prevention of cardiovascular diseases.
PT2020-SAICT-PTDC/ICDT-032492
POCI-01-0145-FEDER-032492
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - Atual CAPEOSBAC - Tailored microenCAPsulation technology for Extreme Oxygen-Sensitive BACteria with beneficial effects on gut microbiota: Production, stability and functionality enhancements in various carriers
PT2020-SAICT-PTDC/ICDT-031400
PTDC/BAA-AGR/31400/2017
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - Atual FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes.
POCI-01-0145-FEDER-031712
Investigador responsável
Fundação para a Ciência e a Tecnologia
Em curso
2023 - 2028 PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
101080329
Investigador
Universidade de Coimbra, Portugal
Horizon Europe
Em curso
2023 - 2026 CHAngeing - Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function
101087071
Investigador
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Horizon Europe Excellent Science
Em curso
2023 - 2026 PRR - Cogumelos do Prado ao Prato: do tratamento de doenças do metabolismo a dieta saudável sustentável a partir da valorização de recursos agro-florestais
PRR-C05-i03-I-000160
Investigador
Universidade de Coimbra, Portugal
European Union
Em curso
2023/01/01 - 2024 LOLit - Low Literacy at Play
2021-1-NL01-KA220-ADU-000033664
Investigador responsável
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Erasmus Plus
Em curso
2023 - 2024 HIVE - HEI Innovation for Knowledge Intensive Entrepreneurship
220818
Investigador
Universidade de Coimbra, Portugal
EIT Health
Em curso
2023 - 2024 GadoNephroRisk - Biomarcadores de lesão renal induzida pelo gadolínio
2022.08400.PTDC
Investigador
Universidade do Porto, Portugal
FCT - Fundação para a Ciência e Tecnologia
Em curso
2022 - 2023 MitoBOOST 2.0 – A proof of concept for the use of mitochondria-targeted polyphenols to treat non-alcoholic fatty liver disease
CENTRO-01-0145-FEDER-181226
Investigador
Universidade de Coimbra, Portugal
FCT and European Regional Development Fund (ERDF)
Concluído
2020 - 2023 ALCHEMY – Capturing high value from industrial fermentation bioproduts
POCI-01-0247-FEDER-02757
Investigador
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
FCT and European Regional Development Fund (ERDF)
Concluído
2021/01/01 - 2022 Healthy Loneliness
1653337
Investigador
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Erasmus Plus
Concluído
2021/01/01 - 2021/12/31 GluVac-COVID19 – Explorar o potencial de ß-glucanas como adjuvantes imunológicos no desenvolvimento de vacinas para a Covid-19
59949
Investigador
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
FCT - Fundação para a Ciência e Teconologia | COMPETE
Concluído
2017 - 2021 HEALTHY AGING 2020
CENTRO-01-0145-FEDER-000012
Investigador
FCT and European Regional Development Fund (ERDF)
Em curso
2020/01/01 - 2020/12/31 Solidão no idoso e pandemia de Covid-19
20515
Investigador
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
European Institute of Innovation & Technology (EIT) - HEALTH
Concluído
2017 - 2020 MOBFOOD - Mobilization of scientific and technological knowledge in response to the challenges of the agrifood market
POCI-01-0247-FEDER-024524
Investigador
ERDF - European Regional Development Fund
Em curso
2017 - 2020 NephroCardio Risk - Reliable biomarkers of chronic kidney disease and of the associated cardiovascular risk. Construction of (bio)sensors for the selected biomarkers
Norte-01-0145-FEDER-000024
Investigador
Em curso
2019/01/01 - 2019/12/31 CRISH 2 – Co-cReating Innovative Solutions for Health 2.0
18053
Investigador
European Institute of Innovation & Technology (EIT) - HEALTH, Alemanha
Concluído
2019/01/01 - 2019/12/31 HEALIQS 4 CITIES – Healthy Lifestyle Innovation Quarters for Cities and Citizens (2019)
19142
Investigador
European Institute of Innovation & Technology (EIT) - HEALTH, Alemanha
Concluído
2019/01/01 - 2019/12/31 Engage Local Players 2019 - EIT RIS (Regional Innovation Scheme)
19513
Investigador
European Institute of Innovation & Technology (EIT) - HEALTH, Alemanha
Concluído
2018/01 - 2018/12 Healthy Lifestyle Innovation Quarters for Cities and Citizens - 2018
18036
EIT Health
2016 - 2018 Targeting p53 family proteins: on the route to new anticancer agentes
PTDC/DTP-FTO/1981/2014
Investigador
FCT - Fundação para a Ciência e Tecnologia
Concluído
2013 - 2015 NANODAIRY - NANOparticles as Delivery systems of bioactive polyphenolic compounds to DAIRY matrices: evaluation of stability, bioavailability and toxicity
PTDC/AGR-ALI/117808/2010
Investigador
FCT - Fundação para a Ciência e Teconologia | COMPETE
Concluído
2012 - 2015 Cross-talk between chronic renal failure, inflammation and erythropoiesis in resistance to recombinant human erythropoietin therapy
PTDC/SAU-TOX/114253/2009
Investigador responsável
FCT - Fundação para a Ciência e Tecnologia
Concluído
2012 - 2013 Regulation of erythropoietin gene expression in non-renal tissues
REISF2
Investigador responsável
FMUC - Faculdade de Medicina da Universidade de Coimbra
Concluído
2012 - 2013 Drug-induced cardiorenal toxicity post-kidney transplantation - biomolecular bases for the choice of protocols of early or late CsA to SRL conversion and of better anti-hypertensive/renoprotective therapeutics
REISF1
Investigador responsável
FMUC - Faculdade de Medicina da Universidade de Coimbra
Concluído
2012 - 2013 DPP-IV inhibitors and GLP-1 as potential therapeutic options for the treatment of diabetic retinopathy: novel insights into the mechanisms of action
EFSD-GSK-2012
Investigador
European Foundation for the Study of Diabetes, Alemanha
Concluído
2011 - 2013 From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders
Projeto Centro-07-ST24-FEDER-002005
Investigador
FEDER - Programa Regional do Centro - QREN
Concluído
2008 - 2010 Risk for cardiovascular events in chronic kidney disease patients under haemodialysis. Lipid profile, anemia, vascular access and inflammation
PIC/IC/83221/2007
Investigador
FCT - Fundação para a Ciência e Tecnologia
Concluído
2007 - 2010 Mechanisms of resistance to recombinant human erythropoietin in patients with chronic renal failure and hemodialysis
PTDC/SAU-FCF/64815/2006
Investigador
FCT - Fundação para a Ciência e Tecnologia
Concluído
2005 - 2007 Prognostic value of inflammatory and oxidative stress markers in psoriasis
POCI/SAU-OBS/58600/2004
Investigador
FCT - Fundação para a Ciência e Tecnologia
Concluído
1998 - 2000 Cyclosporin effects in smooth muscle stimulation and proliferation: propose of preventive drugs
PRAXIS/PSAU/C/SAU/57/96
Investigador
FCT - Fundação para a Ciência e Tecnologia
Concluído
1996 - 1998 Drug-induced acute pancreatitis - European Pharmacological Research Group
BIOMED 2 project (BMH4-CT95-0467)
Bolseiro de Técnico de Investigação
European Community - BIOMED 2
Concluído
Produções

Publicações

Artigo em revista
  1. Rosendo-Silva, Daniela; Gomes, Pedro Bastos; Rodrigues, Tiago; Viana, Sofia; da Costa, André Nogueira; Scherer, Philipp E.; Reis, Flávio; et al. "Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction". Metabolism 153 (2024): 155788. http://dx.doi.org/10.1016/j.metabol.2024.155788.
    Acesso aberto • Publicado • 10.1016/j.metabol.2024.155788
  2. Reis, Flávio; Fernandes, Rosa. "Molecular Pharmacology in Diabetes". International Journal of Molecular Sciences 25 5 (2024): 3051. http://dx.doi.org/10.3390/ijms25053051.
    10.3390/ijms25053051
  3. Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; et al. "Effect of Blueberry Supplementation on a Diet-Induced Rat Model of Prediabetes—Focus on Hepatic Lipid Deposition, Endoplasmic Stress Response and Autophagy". Nutrients 16 4 (2024): 513. http://dx.doi.org/10.3390/nu16040513.
    10.3390/nu16040513
  4. Das, Anindita; Reis, Flávio. "mTOR Signaling: New Insights into Cancer, Cardiovascular Diseases, Diabetes and Aging". International Journal of Molecular Sciences 24 17 (2023): 13628. http://dx.doi.org/10.3390/ijms241713628.
    Acesso aberto • Publicado • 10.3390/ijms241713628
  5. Sousa, Adelaide; Azevedo, Rui; Costa, Vera Marisa; Oliveira, Sara; Preguiça, Inês; Viana, Sofia; Reis, Flávio; et al. "Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology 97 10 (2023): 2643-2657. http://dx.doi.org/10.1007/s00204-023-03558-5.
    Acesso aberto • Publicado • 10.1007/s00204-023-03558-5
  6. Garcia, Karina; Alves, André; Ribeiro-Rodrigues, Teresa M.; Reis, Flávio; Viana, Sofia. "Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment". Journal of Visualized Experiments 196 (2023): http://dx.doi.org/10.3791/65206.
    Acesso aberto • Publicado • 10.3791/65206
  7. Reis, Flávio. "Gut microbiota dysbiosis and cardiovascular disease – The chicken and the egg". Revista Portuguesa de Cardiologia 42 6 (2023): 553-555. http://dx.doi.org/10.1016/j.repc.2023.03.004.
    Acesso aberto • Publicado • 10.1016/j.repc.2023.03.004
  8. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "Reply to the Comment on “1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis”". Pharmacological Research 191 (2023): 106623. http://dx.doi.org/10.1016/j.phrs.2022.106623.
    Publicado • 10.1016/j.phrs.2022.106623
  9. Rosendo-Silva, Daniela; Viana, Sofia; Carvalho, Eugénia; Reis, Flávio; Matafome, Paulo. "Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved". Internal and Emergency Medicine 18 5 (2023): 1287-1302. http://dx.doi.org/10.1007/s11739-023-03262-3.
    Acesso aberto • Publicado • 10.1007/s11739-023-03262-3
  10. Lousa, Irina; Reis, Flávio; Viana, Sofia; Vieira, Pedro; Vala, Helena; Belo, Luís; Santos-Silva, Alice. "TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD". Biomolecules 13 3 (2023): 534. http://dx.doi.org/10.3390/biom13030534.
    Acesso aberto • Publicado • 10.3390/biom13030534
  11. Garcia, Karina; Ferreira, Gonçalo; Reis, Flávio; Viana, Sofia. "Impact of Dietary Sugars on Gut Microbiota and Metabolic Health". Diabetology 3 4 (2022): 549-560. http://dx.doi.org/10.3390/diabetology3040042.
    Acesso aberto • Publicado • 10.3390/diabetology3040042
  12. Palavra, Filipe; Viana, Sofia D.; Henriques, Sara; Dinis, João; Martins, João; Madeira, Maria H.; Santiago, Raquel; et al. "Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?". Multiple Sclerosis and Related Disorders 63 (2022): 103886. http://dx.doi.org/10.1016/j.msard.2022.103886.
    Acesso aberto • Publicado • 10.1016/j.msard.2022.103886
  13. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis". Pharmacological Research 180 (2022): 106151. http://dx.doi.org/10.1016/j.phrs.2022.106151.
    Acesso aberto • Publicado • 10.1016/j.phrs.2022.106151
  14. Amorim, Madania; Martins, Beatriz; Caramelo, Francisco; Gonçalves, Conceição; Trindade, Grimalde; Simão, Jorge; Barreto, Patrícia; et al. "Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis". Frontiers in Medicine 9 (2022): http://dx.doi.org/10.3389/fmed.2022.873483.
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  15. Lousa, Irina; Belo, Luís; Valente, Maria João; Rocha, Susana; Preguiça, Inês; Rocha-Pereira, Petronila; Beirão, Idalina; et al. "Inflammatory biomarkers in staging of chronic kidney disease: elevated TNFR2 levels accompanies renal function decline". Inflammation Research 71 5-6 (2022): 591-602. http://dx.doi.org/10.1007/s00011-022-01574-2.
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  16. Lousa, Irina; Reis, Flávio; Santos-Silva, Alice; Belo, Luís. "The Signaling Pathway of TNF Receptors: Linking Animal Models of Renal Disease to Human CKD". International Journal of Molecular Sciences 23 6 (2022): 3284. http://dx.doi.org/10.3390/ijms23063284.
    Publicado • 10.3390/ijms23063284
  17. Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Patrícia Matos; et al. "Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics". Nutrients (2021): https://www.mdpi.com/2072-6643/13/12/4192.
    10.3390/nu13124192
  18. Sara Nunes; Pedro Vieira; Pedro Gomes; Sofia Domingues Viana; Reis F. "Blueberry as An Attractive Functional Fruit to Prevent (Pre)Diabetes Progression". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/8/1162.
    10.3390/antiox10081162
  19. Susana Coimbra; Reis F; Maria João Valente; S. Rocha; Cristina Catarino; Petronila Rocha-Pereira; Maria Sameiro-Faria; et al. "Subpopulations of High-Density Lipoprotein: Friends or Foes in Cardiovascular Disease Risk in Chronic Kidney Disease?". Biomedicines (2021): https://www.mdpi.com/2227-9059/9/5/554.
    10.3390/biomedicines9050554
  20. Nuno Henrique Franco; Sónia Miranda; Nóra Kovács; Attila Nagy; Bùi Qu¿c Thi¿n; Reis F; Orsolya Varga. "Assessing Scientific Soundness and Translational Value of Animal Studies on DPP4 Inhibitors for Treating Type 2 Diabetes Mellitus". Biology (2021): https://www.mdpi.com/2079-7737/10/2/155.
    10.3390/biology10020155
  21. Ramos, H.; Soares, M.I.L.; Silva, J.; Raimundo, L.; Calheiros, J.; Gomes, C.; Reis, F.; et al. "A selective p53 activator and anticancer agent to improve colorectal cancer therapy". Cell Reports 35 2 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104050337&partnerID=MN8TOARS.
    10.1016/j.celrep.2021.108982
  22. Pandey, A.K.; Kumar, S.; Reis, F.. "Editorial: Combating Redox Imbalance-Associated Complications With Natural Products". Frontiers in Pharmacology 12 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85121004209&partnerID=MN8TOARS.
    10.3389/fphar.2021.802750
  23. Azul, A.M.; Almendra, R.; Quatorze, M.; Loureiro, A.; Reis, F.; Tavares, R.; Mota-Pinto, A.; et al. "Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study". BMC public health 21 1 (2021): 1628-1628. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115819445&partnerID=MN8TOARS.
    10.1186/s12889-021-11661-4
  24. Irina Lousa; Reis F; Idalina Beirão; Rui Alves; Luís Belo; Alice Santos-Silva. "New Potential Biomarkers for Chronic Kidney Disease Management—A Review of the Literature". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/22/1/43.
    10.3390/ijms22010043
  25. Carolina Ferreira; Sofia D. Viana; Reis F. "Is Gut Microbiota Dysbiosis a Predictor of Increased Susceptibility to Poor Outcome of COVID-19 Patients? An Update". Microorganisms (2020): https://www.mdpi.com/2076-2607/9/1/53.
    10.3390/microorganisms9010053
  26. Picó C; Reis F; Egas C; Mathias P; Matafome P. "Lactation as a programming window for metabolic syndrome.". European journal of clinical investigation (2020): http://europepmc.org/abstract/med/33350459.
    10.1111/eci.13482
  27. Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Artur Figueirinha; et al. "Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats". Pharmaceutics (2020): https://www.mdpi.com/1999-4923/12/11/1094.
    10.3390/pharmaceutics12111094
  28. Carolina Ferreira; Sofia D. Viana; Reis F. "Gut Microbiota Dysbiosis–Immune Hyperresponse–Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches". Microorganisms (2020): https://www.mdpi.com/2076-2607/8/10/1514.
    10.3390/microorganisms8101514
  29. Beatriz Martins; Madania Amorim; Reis F; António F Ambrósio; R. Fernandes. "Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy". Antioxidants (2020): https://www.mdpi.com/2076-3921/9/8/705.
    10.3390/antiox9080705
  30. Viana SD; Nunes S; Reis F. "ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities - Role of gut microbiota dysbiosis.". Ageing research reviews (2020): http://europepmc.org/abstract/med/32683039.
    10.1016/j.arr.2020.101123
  31. Preguiça I; Alves A; Nunes S; Fernandes R; Gomes P; Viana SD; Reis F. "Diet-induced rodent models of obesity-related metabolic disorders-A guide to a translational perspective.". Obesity reviews : an official journal of the International Association for the Study of Obesity (2020): http://europepmc.org/abstract/med/32691524.
    10.1111/obr.13081
  32. Sara Nunes; André Alves; Inês Preguiça; Adelaide Barbosa; Pedro Vieira; Fernando Mendes; Diana Martins; Sofia D. Viana; Reis F. "Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet". Nutrients (2020): https://www.mdpi.com/2072-6643/12/4/881.
    10.3390/nu12040881
  33. Reis, Flávio. "Diet-Induced Rodent Models of Diabetic Peripheral Neuropathy, Retinopathy and Nephropathy". Nutrients (2020): http://dx.doi.org/10.3390/nu12010250.
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  34. Gomes P; Leal H; Mendes AF; Reis F; Cavadas C. "Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases.". Trends in pharmacological sciences (2019): http://europepmc.org/abstract/med/31704173.
    10.1016/j.tips.2019.09.003
  35. Gomes P; Viana SD; Nunes S; Rolo AP; Palmeira CM; Reis F. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders.". Ageing research reviews (2019): http://europepmc.org/abstract/med/31740222.
    10.1016/j.arr.2019.100983
  36. Amit Kumar Singh; Célia Cabral; Ramesh Kumar; Risha Ganguly; Harvesh Kumar Rana; ASHUTOSH GUPTA; Maria Rosaria Lauro; et al. "Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency". Nutrients (2019): https://www.mdpi.com/2072-6643/11/9/2216.
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  37. Marques C; Gonçalves A; Pereira PMR; Almeida D; Martins B; Fontes-Ribeiro C; Reis F; Fernandes R. "The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes.". Life sciences (2019): http://europepmc.org/abstract/med/31398418.
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  38. Gomes S; Bosco B; Loureiro JB; Ramos H; Raimundo L; Soares J; Nazareth N; et al. "SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.". Cancers (2019): http://europepmc.org/abstract/med/31405179.
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  39. Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al. "Development of a Healthy Lifestyle Assessment Toolkit for the General Public.". Frontiers in medicine (2019): http://europepmc.org/abstract/med/31316985.
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  40. Das A; Reis F; Mishra PK. "mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging 2018.". Oxidative medicine and cellular longevity (2019): http://europepmc.org/abstract/med/30863483.
    10.1155/2019/9692528
  41. Coimbra S; Reis F; Nunes S; Viana S; Valente MJ; Rocha S; Catarino C; et al. "The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index.". Oxidative medicine and cellular longevity (2019): http://europepmc.org/abstract/med/30911344.
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  42. Coimbra S; Reis F; Ferreira C; Nunes S; Viana S; Catarino A; Rocha-Pereira P; et al. "Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection.". Clinical biochemistry (2018): http://europepmc.org/abstract/med/30342017.
    10.1016/j.clinbiochem.2018.10.007
  43. Fernandes R; Viana SD; Nunes S; Reis F. "Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy.". Biochimica et biophysica acta. Molecular basis of disease (2018): http://europepmc.org/abstract/med/30287404.
    10.1016/j.bbadis.2018.09.032
  44. Viana SD; Reis F; Alves R. "Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges.". Oxidative medicine and cellular longevity (2018): http://europepmc.org/abstract/med/30510618.
    10.1155/2018/3693625
  45. Alves MRP; Boia R; Campos EJ; Martins J; Nunes S; Madeira MH; Santiago AR; et al. "Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes.". Molecular vision (2018): http://europepmc.org/abstract/med/29853770.
  46. Lousa I; Nascimento H; Rocha S; Catarino C; Reis F; Rêgo C; Santos-Silva A; et al. "Influence of the 6-month physical activity programs on renal function in obese boys.". Pediatric research (2018): http://europepmc.org/abstract/med/29638229.
    10.1038/pr.2018.15
  47. Teodoro JS; Nunes S; Rolo AP; Reis F; Palmeira CM. "Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes.". Frontiers in physiology (2018): http://europepmc.org/abstract/med/30705633.
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  48. Reis, Flávio. "Bridging health and social care with the citizens – the case of eit health project “HeaLIQs4Cities” and “praça vida+”, in Portugal". Care Weekly 2 (2018): 21-24.
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  49. Alves, M.R.P.; Boia, R.; Campos, E.J.; Martins, J.; Nunes, S.; Madeira, M.H.; Santiago, A.R.; et al. "Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes". Molecular Vision 24 (2018): 353-366. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050808197&partnerID=MN8TOARS.
  50. Reis, Flávio. "Discovery of a small-molecule protein kinase Cd-selective activator with promising application in colon cancer therapy". Cell Death & Disease (2017):
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  51. Reis, Flávio. "Therapeutic strategies targeting oxidative stress to improve dyslipidemia and left ventricular hypertrophy.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2017): http://europepmc.org/abstract/med/28826936.
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  52. Reis, Flávio. "Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet.". Nutrients (2017): http://europepmc.org/abstract/med/28635632.
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  53. Soares J; Espadinha M; Raimundo L; Ramos H; Gomes AS; Gomes S; Loureiro JB; et al. "DIMP53-1: A novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.". (2017): http://europepmc.org/abstract/med/28296148.
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  54. Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F.. "Solid lipid nanoparticles as oral delivery systems of phenolic compounds: Overcoming pharmacokinetic limitations for nutraceutical applications". Critical Reviews in Food Science and Nutrition 57 9 (2017): 1863-1873. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014884555&partnerID=MN8TOARS.
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  55. Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F.. "Therapeutic and nutraceutical potential of rosmarinic acid—Cytoprotective properties and pharmacokinetic profile". Critical Reviews in Food Science and Nutrition 57 9 (2017): 1799-1806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014885468&partnerID=MN8TOARS.
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  57. Reis, Flávio. "Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes.". Journal of diabetes research (2017): http://europepmc.org/abstract/med/29098166.
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  58. Palavra F; Robalo C; Reis F. "Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex.". (2017): http://europepmc.org/abstract/med/28386314.
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  59. García-Casarrubios E; de Moura C; Arroba AI; Pescador N; Calderon-Dominguez M; Garcia L; Herrero L; et al. "Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.". (2016): http://europepmc.org/abstract/med/27686967.
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  60. Ferreira-Teixeira M; Paiva-Oliveira D; Parada B; Alves V; Sousa V; Chijioke O; Münz C; et al. "Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells.". (2016): http://europepmc.org/abstract/med/27769244.
  61. Ribeiro S; Garrido P; Fernandes J; Rocha S; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.". (2016): http://europepmc.org/abstract/med/27282570.
    10.1016/j.bcmd.2016.04.008
  62. João AL; Reis F; Fernandes R. "The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond.". (2016): http://europepmc.org/abstract/med/27125902.
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  63. Palavra F; Almeida L; Ambrósio AF; Reis F. "Obesity and brain inflammation: a focus on multiple sclerosis.". (2016): http://europepmc.org/abstract/med/26783119.
    10.1111/obr.12363
  64. Ribeiro S; Garrido P; Fernandes J; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses.". (2016): http://europepmc.org/abstract/med/26990350.
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  65. Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia.". (2016): http://europepmc.org/abstract/med/27039028.
  66. Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM. "Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval.". (2016): http://europepmc.org/abstract/med/26846768.
  67. Lemos C; Rial D; Gonçalves FQ; Pires J; Silva HB; Matheus FC; da Silva AC; et al. "High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus.". (2016): http://europepmc.org/abstract/med/26704636.
    10.1016/j.neuroscience.2015.12.018
  68. Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM. "A fast and reliable method for GHB quantitation in whole blood by GC-MS/MS (TQD) for forensic purposes.". (2016): http://europepmc.org/abstract/med/26678181.
    10.1016/j.jpba.2015.11.038
  69. Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat.". (2016): http://europepmc.org/abstract/med/26924494.
    10.1016/j.lfs.2016.02.088
  70. Madureira AR; Nunes S; Campos DA; Fernandes JC; Marques C; Zuzarte M; Gullón B; et al. "Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches.". (2016): http://europepmc.org/abstract/med/27536103.
    10.2147/ijn.s104623
  71. Reis, Flávio. "Renal risk-benefits determinants of recombinant human erythropoietin therapy in the remnant kidney rat model – hypertension, anaemia, infammation and drug dose". Clin Exp Pharmacol and Physiol (2016):
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  72. Ferreira-Teixeira, M.; Paiva-Oliveira, D.; Parada, B.; Alves, V.; Sousa, V.; Chijioke, O.; Münz, C.; et al. "Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells". BMC Medicine 14 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992153376&partnerID=MN8TOARS.
    10.1186/s12916-016-0715-2
  73. Castro, A.L.; Tarelho, S.; Dias, M.; Reis, F.; Teixeira, H.M.. "Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval". International Journal of Legal Medicine 130 4 (2016): 959-965. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957591999&partnerID=MN8TOARS.
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  74. Ribeiro, S.; Belo, L.; Reis, F.; Santos-Silva, A.. "Iron therapy in chronic kidney disease: Recent changes, benefits and risks". Blood Reviews 30 1 (2016): 65-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960312577&partnerID=MN8TOARS.
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  75. Ribeiro, S.; Garrido, P.; Fernandes, J.; Vala, H.; Rocha-Pereira, P.; Costa, E.; Belo, L.; Reis, F.; Santos-Silva, A.. "Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia". Biochimie 125 (2016): 150-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964388884&partnerID=MN8TOARS.
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  76. Soares J; Raimundo L; Pereira NA; Monteiro Â; Gomes S; Bessa C; Pereira C; et al. "Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.". (2015): http://europepmc.org/abstract/med/26735173.
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  77. Ribeiro S; Belo L; Reis F; Santos-Silva A. "Iron therapy in chronic kidney disease: Recent changes, benefits and risks.". (2015): http://europepmc.org/abstract/med/26342303.
  78. Sereno J; Vala H; Nunes S; Rocha-Pereira P; Carvalho E; Alves R; Teixeira F; Reis F. "Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.". (2015): http://europepmc.org/abstract/med/25903959.
  79. Garrido P; Ribeiro S; Fernandes J; Vala H; Rocha-Pereira P; Bronze-da-Rocha E; Belo L; et al. "Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia.". (2015): http://europepmc.org/abstract/med/26712750.
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  80. Reis, Flávio. "Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors.". Oncotarget (2015):
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  81. Garrido P; Ribeiro S; Fernandes J; Vala H; Bronze-da-Rocha E; Rocha-Pereira P; Belo L; et al. "Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.". (2015): http://europepmc.org/abstract/med/25867633.
    10.1371/journal.pone.0124048
  82. Godinho R; Mega C; Teixeira-de-Lemos E; Carvalho E; Teixeira F; Fernandes R; Reis F. "The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?". (2015): http://europepmc.org/abstract/med/26075286.
    10.1155/2015/806979
  83. Madureira, Ana Raquel; Campos, Débora A.; Fonte, Pedro; Nunes, Sara; Reis, Flávio; Gomes, Ana Maria; Sarmento, Bruno; Pintado, Maria Manuela. "Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery". RSC Advances 5 29 (2015): 22665-22673. http://dx.doi.org/10.1039/c4ra15802d.
    Publicado • 10.1039/c4ra15802d
  84. Sereno, J.; Vala, H.; Nunes, S.; Rocha-Pereira, P.; Carvalho, E.; Alves, R.; Teixeira, F.; Reis, F.. "Cyclosporine a-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat". Journal of Physiology and Pharmacology 66 2 (2015): 285-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927565139&partnerID=MN8TOARS.
  85. Costa E; Fernandes J; Ribeiro S; Sereno J; Garrido P; Rocha-Pereira P; Coimbra S; et al. "Aging is Associated with Impaired Renal Function, INF-gamma Induced Inflammation and with Alterations in Iron Regulatory Proteins Gene Expression.". (2014): http://europepmc.org/abstract/med/25489488.
    10.14366/AD.2014.0500356
  86. Castro AL; Dias M; Reis F; Teixeira HM. "Gamma-hydroxybutyric acid endogenous production and post-mortem behaviour - the importance of different biological matrices, cut-off reference values, sample collection and storage conditions.". (2014): http://europepmc.org/abstract/med/25287794.
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  87. Gonçalves A; Marques C; Leal E; Ribeiro CF; Reis F; Ambrósio AF; Fernandes R. "Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats.". (2014): http://europepmc.org/abstract/med/24769045.
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  88. Lopes PC; Fuhrmann A; Carvalho F; Sereno J; Santos MR; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment.". (2014): http://europepmc.org/abstract/med/24960264.
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  89. Lopes PC; Fuhrmann A; Sereno J; Espinoza DO; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats.". (2014): http://europepmc.org/abstract/med/24656168.
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  149. Costa, E.; Swinkels, D.W.; Laarakkers, C.M.; Rocha-Pereira, P.; Rocha, S.; Reis, F.; Teixeira, F.; et al. "Hepcidin serum levels and resistance to recombinant human erythropoietin therapy in haemodialysis patients". Acta Haematologica 122 4 (2009): 226-229. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350521582&partnerID=MN8TOARS.
    10.1159/000253590
  150. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al. "Circulating levels of adiponectin, oxidized LDL and C-reactive protein in Portuguese patients with psoriasis vulgaris, according to body mass index, severity and duration of the disease". Journal of Dermatological Science 55 3 (2009): 202-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651026846&partnerID=MN8TOARS.
    10.1016/j.jdermsci.2009.05.008
  151. Parada, B.; Sereno, J.; Reis, F.; Teixeira-Lemos, E.; Garrido, P.; Pinto, A.F.; Cunha, M.F.; et al. "Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis". Cancer Biology and Therapy 8 17 (2009): 1615-1622. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350306703&partnerID=MN8TOARS.
    10.4161/cbt.8.17.9199
  152. Garrido, P.; Reis, F.; Costa, E.; Teixeira-Lemos, E.; Parada, B.; Alves, R.; Piloto, N.; et al. "Characterization of a rat model of moderate chronic renal failurefocus on hematological, biochemical, and cardio-renal profiles". Renal Failure 31 9 (2009): 833-842. http://www.scopus.com/inward/record.url?eid=2-s2.0-71049184825&partnerID=MN8TOARS.
    10.3109/08860220903151435
  153. Piloto, N.; Teixeira, H.M.; Teixeira-Lemos, E.; Parada, B.; Garrido, P.; Sereno, J.; Pinto, R.; et al. "Erythropoietin promotes deleterious cardiovascular effects and mortality risk in a rat model of chronic sports doping". Cardiovascular Toxicology 9 4 (2009): 201-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949111878&partnerID=MN8TOARS.
    10.1007/s12012-009-9054-2
  154. Teixeira de Lemos, E.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; et al. "Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats". Nutrition 25 3 (2009): 330-339. http://www.scopus.com/inward/record.url?eid=2-s2.0-60349095336&partnerID=MN8TOARS.
    10.1016/j.nut.2008.08.014
  155. Reis, F.; Parada, B.; Teixeira de Lemos, E.; Garrido, P.; Dias, A.; Piloto, N.; Baptista, S.; et al. "Hypertension Induced by Immunosuppressive Drugs: A Comparative Analysis Between Sirolimus and Cyclosporine". Transplantation Proceedings 41 3 (2009): 868-873. http://www.scopus.com/inward/record.url?eid=2-s2.0-64649096675&partnerID=MN8TOARS.
    10.1016/j.transproceed.2009.02.005
  156. Costa, E.; Pereira, B.J.G.; Rocha-Pereira, P.; Rocha, S.; Reis, F.; Castro, E.; Teixeira, F.; et al. "Role of prohepcidin, inflammatory markers and iron status in resistance to rhEPO therapy in hemodialysis patients". American Journal of Nephrology 28 4 (2008): 677-683. http://www.scopus.com/inward/record.url?eid=2-s2.0-45149099284&partnerID=MN8TOARS.
    10.1159/000121478
  157. Costa, E.; Rocha, S.; Rocha-Pereira, P.; Reis, F.; Castro, E.; Teixeira, F.; Miranda, V.; et al. "DMT1 (NRAMP2/DCT1) Genetic Variability and Resistance to Recombinant Human Erythropoietin Therapy in Chronic Kidney Disease Patients under Haemodialysis". Acta Haematologica 120 1 (2008): 11-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049113949&partnerID=MN8TOARS.
    10.1159/000149496
  158. Costa, E.; Rocha, S.; Rocha-Pereira, P.; Castro, E.; Reis, F.; Teixeira, F.; Miranda, V.; et al. "Cross-talk between inflammation, coagulation/fibrinolysis and vascular access in hemodialysis patients". Journal of Vascular Access 9 4 (2008): 248-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-60549110919&partnerID=MN8TOARS.
  159. Baptista, S.; Piloto, N.; Reis, F.; Teixeira-De-Lemos, E.; Garrido, A.P.; Dias, A.; Lourenço, M.; et al. "Treadmill running and swimming imposes distinct cardiovascular physiological adaptations in the rat: Focus on serotonergic and sympathetic nervous systems modulation". Acta Physiologica Hungarica 95 4 (2008): 365-381. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949097707&partnerID=MN8TOARS.
    10.1556/APhysiol.2008.0002
  160. Reis, F.; Teixeira de Lemos, E.; Almeida, L.; Parada, B.; Garrido, A.P.; Rocha-Pereira, P.; Santos-Silva, A.; et al. "Dual Effect of Nitrate Therapy for Cyclosporine-Induced Hypertension on Vascular and Platelet Morphofunctional Markers; An Animal Model". Transplantation Proceedings 39 8 (2007): 2501-2506. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348827321&partnerID=MN8TOARS.
    10.1016/j.transproceed.2007.07.029
  161. De Lemos, E.T.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; Silva, A.S.; Teixeira, F.. "Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats". Medical Science Monitor 13 8 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-34548396344&partnerID=MN8TOARS.
  162. Reis, F.; Rocha-Pereira, P.; Teixeira de Lemos, E.; Parada, B.; Baptista, S.; Figueiredo, A.; Santos-Silva, A.; et al. "Oxidative Stress in Cyclosporine-Induced Hypertension: Evidence of Beneficial Effects or Tolerance Development With Nitrate Therapy". Transplantation Proceedings 39 8 (2007): 2494-2500. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348866153&partnerID=MN8TOARS.
    10.1016/j.transproceed.2007.07.030
  163. Reis, F.; Ponte, L.; Rocha, L.; Teixeira-Lemos, E.; Almeida, L.; Alcobia, T.; Lourenço, M.; et al. "Curative isosorbide-5-mononitrate treatment, in opposition to the beneficial preventive one, aggravates the prothrombotic and proconstrictor state in cyclosporine-induced hypertensive rats". Clinical and Experimental Pharmacology and Physiology 32 8 (2005): 640-648. http://www.scopus.com/inward/record.url?eid=2-s2.0-22644435282&partnerID=MN8TOARS.
    10.1111/j.0305-1870.2005.04244.x
  164. Reis, F.; Rocha, L.; Ponte, L.; Alcobia, T.; Almeida, L.; Costa-Almeida, C.; Teixeira, F.. "Effect of preventive and regressive isosorbide 5-mononitrate treatment on catecholamine levels in plasma, platelets, adrenals, left ventricle and aorta in cyclosporin A-induced hypertensive rats". Life Sciences 77 20 (2005): 2514-2528. http://www.scopus.com/inward/record.url?eid=2-s2.0-24044545901&partnerID=MN8TOARS.
    10.1016/j.lfs.2005.01.032
  165. Reis, F.; Campos, M.V.; Bastos, M.; Almeida, L.; Lourenço, M.; Ferrer-Antunes, C.A.; Palmeiro, A.; et al. "Platelet hyperactivation in maintained growth hormone-deficient childhood patients after therapy withdrawal as a putative earlier marker of increased cardiovascular risk". Journal of Clinical Endocrinology and Metabolism 90 1 (2005): 98-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-19944427824&partnerID=MN8TOARS.
    10.1210/jc.2004-0477
  166. Teixeira HM; Reis F; Proença P; Ramos P; Quintela O; López-Rivadulla M; Marques E; Vieira DN. "Vitreous humour as a complementary sample to blood for the detection/confirmation of diazepam: ante-mortem and post-mortem studies in an animal model.". (2004): http://europepmc.org/abstract/med/15688985.
    10.1191/0960327104ht490oa
  167. Santiago, M.; Reis, F.; Almeida, L.; Alcobia, T.; Dionísio, J.; Teixeira, F.. "Impairment of vascular and platelet levels of nitric oxide and cyclic guanosine-',5'-monophosphate in cyclosporin A-induced hypertensive rats". Fundamental and Clinical Pharmacology 17 1 (2003): 43-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037326672&partnerID=MN8TOARS.
    10.1046/j.1472-8206.2003.00116.x
  168. Reis, F.; Almeida, L.; Alcobia, T.; Santos-Dias, J.D.; Lourenço, M.; Palmeiro, A.; Ferrer-Antunes, C.A.; et al. "Isosorbide-5-mononitrate treatment prevents cyclosporin A-induced platelet hyperactivation and the underlying nitric oxide-cyclic guanosine-3', 5'-monophosphate disturbances". Thrombosis Research 110 2-3 (2003): 107-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744223826&partnerID=MN8TOARS.
    10.1016/S0049-3848(03)00311-6
  169. Reis, F.; Hermida, R.C.; Souza, I.; Maldonado, J.; Tavares, P.; Fontes-Ribeiro, C.A.; Teixeira, H.M.; et al. "Circadian and seasonal variation of endogenous ubiquinone plasma level". Chronobiology International 19 3 (2002): 599-614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035989775&partnerID=MN8TOARS.
    10.1081/CBI-120004544
  170. Tavares, P.; Reis, F.; Fontes Ribeiro, C.A.; Teixeira, F.. "Cardiovascular effects of cyclosporin treatment in an experimental model | Efeitos cardiovasculares da ciclosporina num modelo experimental". Revista Portuguesa de Cardiologia 21 2 (2002): 141-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036129786&partnerID=MN8TOARS.
  171. Reis, F.; Tavares, P.; Rito, L.C.; Teixeira, H.M.; Santos Dias, J.D.; Ferrer-Antunes, C.; Mesquita, J.F.; Teixeira, F.. "Platelet activation is increased in cyclosporin A-induced hypertensive rats". Journal of Cardiovascular Pharmacology 36 1 (2000): 56-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033937676&partnerID=MN8TOARS.
  172. Reis, F.; Tavares, P.; Teixeira, F.. "The distribution of catecholamines between plasma and platelets in cyclosporin A-induced hypertensive rats". Pharmacological Research 41 2 (2000): 129-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033839925&partnerID=MN8TOARS.
    10.1006/phrs.1999.0572
  173. Reis, F.; Tavares, P.; Ribeiro, C.A.F.; Antunes, F.; Teixeira, F.. "The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats". Thrombosis Research 96 5 (1999): 365-372. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032762622&partnerID=MN8TOARS.
    10.1016/S0049-3848(99)00115-2
Capítulo de livro
  1. Flávio Reis. "Microbiota intestinal (Cap. 4)". In Manual de lípidos. Portugal: Cultura Editora, 2021.
    Publicado
  2. Reis, Flávio. "TUBEROUS SCLEROSIS COMPLEX (Chapter 99)". In Handbook of Tumor Syndromes. Taylor and Francis CRC Press, 2020.
    No prelo
  3. Santos-Silva A; Ribeiro S; Reis F; Belo L. "Hepcidin in chronic kidney disease anemia (Chapter 12)". In Vitamins and hormones. Elsevier Inc., 2019.
    Publicado • 10.1016/bs.vh.2019.01.012
  4. Reis, Flávio. "O RIM COMO ÓRGÃO-ALVO DA TOXICIDADE DE XENOBIÓTICOS (Capítulo 6)". In Toxicologia Fundamental. Lidel, 2018.
    Publicado
  5. Patel, Bhoomika M.. "DIABETIC CARDIOMYOPATHY: FOCUS ON OXIDATIVE STRESS, MITOCHONDRIAL DYSFUNCTION AND INFLAMMATION (Chapter 12)". In Cardiomyopathies - Types and Treatments, 413-425. InTech, 2017.
    Publicado • 10.1007/978-981-13-8273-4_18
  6. Reis, Flávio. "THE HIF SYSTEM RESPONSE TO ESA THERAPY IN CKD-ANEMIA (Chapter 14)". In Hypoxia and Human Diseases. InTech, 2017.
    Publicado
  7. Reis, Flávio. "DIABETIC CARDIOMYOPATHY: FOCUS ON OXIDATIVE STRESS, MITOCHONDRIAL DYSFUNCTION AND INFLAMMATION (Chapter 12) - Authors: Sara Nunes, Anabela Pinto Rolo, Carlos Manuel Palmeira and Flávio Reis". 2017.
  8. Reis, Flávio. "mTOR and Neuroinflammation (Chapter 19)". In Molecules to Medicine with mTOR, 317-329. Elsevier, 2016.
    Publicado • 10.1016/B978-0-12-802733-2.00002-5
  9. Reis, Flávio. "mTOR in Diabetic Nephropathy and Retinopathy (Chapter 23)". In Molecules to Medicine with mTOR, 379-393. Elsevier, 2016.
    Publicado • 10.1016/B978-0-12-802733-2.00001-3
  10. Reis, Flávio. "INFLAMMATION BIOMARKERS AND CARDIOMETABOLIC RISK (Chapter 1)". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease, 1-24. Springer International Publishing, 2015.
    Publicado • 10.1007/978-3-319-16018-4_1
  11. Reis, Flávio. "CARDIOVASCULAR DISEASE (Chapter 2)". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer International Publishing, 2015.
    Publicado • 10.1007/978-3-319-16018-4_2
  12. Reis, Flávio. "RHEPO FOR THE TREATMENT OF ERYTHROPOIETIN RESISTANT ANEMIA IN HEMODIALYSIS PATIENTS – RISKS AND BENEFITS (Chapter 16)". In Hemodialysis. InTech, 2013.
    Publicado • 10.5772/52061
  13. Reis, Flávio. "REGULATION OF ERYTHROPOIETIN GENE EXPRESSION (Chapter 2)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Publicado
  14. Reis, Flávio. "ANIMAL MODELS OF KIDNEY DISEASE-ASSOCIATED ANEMIA (Chapter 4)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Publicado
  15. Reis, Flávio. "RISKS AND BENEFITS ASSOCIATED WITH HIGH THERAPEUTIC DOSES OF ERYTHROPOIESIS STIMULATING AGENTS (Chapter 5)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Publicado
  16. Reis, Flávio. "PHYSICAL ACTIVITY AND INFLAMMATION – AN OVERVIEW (Chapter 21)". In Chronic inflammation: molecular pathophysiology, nutritional and therapeutic interventions. CRC Press, 2012.
    Publicado
  17. Reis, Flávio. "CANNABINOIDS: FORENSIC TOXICOLOGY AND THERAPEUTICS (Chapter 10)". In Forensic Medicine - From Old Problems to New Challenges. InTech, 2011.
    Publicado
  18. Reis, Flávio. "PSORIASIS COMORBIDITIES AND THE INCIDENCE OF RISK FACTORS FOR CARDIOVASCULAR DISEASE EVENTS IN PSORIASIS (Chapter 5)". In Psoriasis: causes, diagnosis and treatment. Nova Science Publishers, 2011.
    Publicado
  19. Reis, Flávio. "CARDIOMETABOLIC INJURY DUE TO RECOMBINANT HUMAN ERYTHROPOIETIN DOPING FOR IMPROVEMENT OF SPORTS PERFORMANCE (Chapter 4)". In Athlete Performance and Injuries. Nova Science Publishers, 2011.
    Publicado
Edição de livro
  1. Reis, Flávio. BIOMARKERS OF CARDIOMETABOLIC RISK, INFLAMMATION AND DISEASE - Springer International Publishing. Springer International Publishing. 2015.
    Publicado • 10.1007/978-3-319-16018-4 • Editor
  2. Reis, Flávio. Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS. 2013.
    Publicado • 10.2174/97816080574741130101 • Editor
Livro
  1. Palavra, F.; Reis, F.; Marado, D.; Sena, A.. Preface. 2015.
  2. Teixeira-Lemos, E.; Teixeira, H.M.; Piloto, N.; Teixeira, M.; Parada, B.; Rodrigues-Santos, P.; Carvalho, L.; et al. Cardiometabolic injury due to recombinant human erythropoietin doping for improvement of sports performance: Chronic (training) versus acute (extenuating) aerobic exercise. 2012.
  3. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; Castro, E.; Rocha-Pereira, P.; Santos-Silva, A.. Psoriasis Comorbidities and the Incidence of Risk Factors for Cardiovascular Disease Events in Psoriasis. 2011.
  4. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; Castro, E.; Rocha-Pereira, P.; Santos-Silva, A.. Psoriasis comorbidities and the incidence of risk factors for cardiovascular disease events in psoriasis. 2011.
Tese / Dissertação
  1. Reis, Flávio. "VASCULAR AND PLATELETARY MECHANISMS IN ARTERIAL HYPERTENSION INDUCED BY CYCLOSPORIN A: PREVENTION WITH A NO DONOR - ISOSSORBIDE 5-MONONITRATE". Doutoramento, 2006.
  2. Reis, Flávio. "EFFECTS OF CYCLOSPORIN A ON PLATELET REACTIVITY IN AN EXPERIMENTAL ANIMAL MODEL". Mestrado, 2000.

Propriedade Intelectual

Patente
  1. Reis, Flávio; Sofia Domingues Viana. 2024. "SEMI-SOLID FORMULATION FOR VOLUNTARY ORAL ADMINISTRATION OF BIOACTIVE COMPOUNDS TO RODENTS (116301)".
    Concedida/Emitida

Outros

Empresa spin-off
  1. 2023. RDefine. Investigação e Desenvolvimento dirigida à melhoria da área preclinica com animais e ao green.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023 - Atual Inflammatory biomarkers in diabetic and non-diabetic renal patients on hemodialysis
Coorientador
Mestrado Integrado em Medicina (Mestrado)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Atual The role of gut microbiome in the senolytic activity of natural compounds explored for prevention of age-related intestinal inflammation. FCT Grant: 2021.08431.BD
Coorientador de Célia Maria da Silva Freitas Costa
Universidade Católica Portuguesa Centro de Investigação em Ciência e Tecnologia das Artes, Portugal
2022 - Atual A deep insight in obesity-associated human adipose tissue dysfunction: identifying new microbial and molecular markers for novel therapeutic approaches. FCT Grant: 2021.08160.BD.
Coorientador de Daniela Rosendo da Silva
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Atual Blueberry leaf biomass: a nutraceutical for Multiple Sclerosis¿ relief by targeting the gut-immune-CNS axis. FCT Grant: 2021.05312.BD
Orientador de Ana Carolina Marques Ferreira
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2021 - Atual The influence of renin-angiotensin system (ras) in pets diabetic dysmotility. FCT Grant : FCT: SFRH/BD/06502/2020
Coorientador de Marisa Manuela Esteves Monteiro
Doutoramento em Ciências Veterinárias (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - Atual Beneficial effects of Faecalibacterium prausnitzii and Akkermansia muciniphila delivery systems in inflammatory bowel disease and prediabetes rodent models FCT Grant: SFRH/BD/09481/2020
Orientador de André Filipe Baltazar Alves
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2021 - Atual A voluntary semi-solid PILL approach for rodent drug dosing - 3R's in motion. FCT Grant: SFRH/BD/08560/2020
Orientador de Inês Mendes Preguiça
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2019 - Atual New biomarkers for chronic kidney disease management
Coorientador de Irina Filipa Lima Lousa
Doutoramento em Ciências Farmacêuticas, ramo de especialização em Bioquímica (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Atual Modeling of pulmonary metastases from osteosarcoma in mice
Coorientador de Nuno Renato Amorim de Lima
Master in Experimental Pathology (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - Atual Impact of a multidisciplinary approach in clinical research on the cardiovascular prognosis and quality of life of patients
Coorientador de Carla Daniela Soares Pais
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - Atual Sirtuin 2 as a new target to revert metabolic dysfunction. FCT Grant: SFRH/BD/121923/2016
Coorientador de Helena Maria da Silva Leal
Doutoramento em Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2015 - Atual Crosstalk between gut microbiota and metabolic dysregulation in prediabetes – Impact of nutraceutical and therapeutic approaches
Orientador de Sara Raquel Ramalho Pereira Nunes
Doutoramento em Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011 - Atual Neuropeptide Y, Y1 receptor and dipeptidyl-peptidase 4: study of the interactions promoting remyelination in an animal model of multiple sclerosis
Orientador de Filipe Manuel Farto Palavra
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - 2026 Bioconversion of blueberry-based agrowastes into functional ingredients with improved immunonutritional value in Chronic Kidney Disease
Coorientador
Programa de doutoramento em ciencias biomédicas (Doutoramento)
Universidade de Coimbra, Portugal
2023 - 2024 Preclinical evaluation of the nutraceutical potential of blueberry-based antioxidant fiber in experimental multiple sclerosis
Coorientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Flavonoids-AhR pharmacodynamics in the gut-immune-kidney axis: therapeutic insights in chronic kidney disease
Coorientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Polyphenols duplibiotic role in Intestinal Inflammatory Disease: focus on next-generation Akkermansia muciniphila
Orientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Remyelination potential of sitagliptin, a DPP-4 inhibitor, in Multiple Sclerosis: a preclinical approach
Coorientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Literacia em saúde na área da polimedicação no idoso – Cocriação de conteúdos no âmbito de um projeto europeu
Orientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 -food interactions of cholesterol-lowering Statins and Mediterranean-based dietary supplements: friends or foes?
Coorientador
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Mestrado)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021 - 2021 Propriedades antiaterogénicas de polifenóis de oliveira e do azeite - Estudo experimental em modelo animal
Orientador de Beatriz Maria Lemos Ormonde
Mestrado em Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2021 Preclinical evaluation of the therapeutic potential of Vaccinium corymbosum L. (blueberry) leaf biomass in experimental Multiple Sclerosis
Coorientador de Ana Carolina Marques Ferreira
Mestrado em Investigação Biomédica (Mestrado)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2019 - 2020 Renal effects of blueberry juice in a prediabetic rat model induced by hypercaloric diet
Orientador de Adelaide Catarina Campos Barbosa
Master in Biomedical Research (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - 2020 Blueberries effects on diet-induced prediabetic nephropathy – an in vivo experimental approach
Coorientador
Mestrado em Química Medicinal (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018 - 2019 Effect of doxorubicin in the treatment of osteosarcoma in mice
Coorientador de Francisca De Brito Ferreira Pinho Pinheiro
Degree in Veterinary Nursing (Licenciatura/Bacharelato)
Instituto Politécnico de Portalegre, Portugal
2017 - 2019 Post-doc Supervision - Projecto HEALTHYAGING 2020 (CENTRO-01-0145-FEDER-000012)
Coorientador de Steve Mendes Catarino
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2018 Effects of incretin-based therapies on the gastrointestinal motility of an animal model of Multiple Sclerosis
Coorientador de Beatriz de Oliveira Martins
Master in Applied Pharmacology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - 2018 Effects of blueberry juice on the evolution of liver dysfunction in an animal model of pre-diabetes
Orientador de Ana Catarina Oliveira Castela
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - 2018 Post-doc Supervision - Projecto HEALTHYAGING 2020 (CENTRO-01-0145-FEDER-000012)
Orientador de Sofia Andreia Domingues Viana
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - 2017 Early remyelination in the murine model exposed to cuprizone: are there any behavioral alterations?
Coorientador de João Paulo Pires Dinis
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2016 Characterization of an animal model of multiple sclerosis - behavioral and biochemical aspects of cuprizone poisoning
Orientador de Sara Carolina Henriques
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2016 The incretin system ABC’s in health and disease – Novel approaches for obesity and diabetes treatment
Coorientador de Ana Luísa Vieira da Natividade Faria João
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2016 Determination of gamma-hydroxybutyric acid (GHB) in blood, urine and hair by GC/MS/MS - Assessment of endogenous and exogenous levels and their application in the areas of Forensic Clinic and Pathology
Coorientador de André Alexandre Lobo Lopes de Castro
Doutoramento em Ciências Forenses (Doutoramento)
Faculdade de Medicina da Universidade do Porto , Portugal
2011 - 2016 Natural Killer cell-based immunotherapy: a new approach for targeting CSCs in bladder cancer
Coorientador de Ana Margarida Ferreira Teixeira
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2016 Anemia and high therapeutic doses of recombinant human erythropoietin in chronic kidney disease – a linkage of risk?
Coorientador de Sandra Patrícia Nunes Ribeiro
Doutoramento em Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015 Post-doc Supervision - Regulation of erythropoietin gene expression in non-renal tissues
Coorientador de João Carlos Azevedo Cruz Gonçalves Fernandes
Universidade de Coimbra Faculdade de Medicina, Portugal
2014 - 2015 Characterization of an animal model of prediabetes
Orientador de Ana Catarina Oliveira Castela
Degree in Biotechnology (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2014 - 2015 Effects of regular and moderate exercise in a prediabetes model
Orientador de Sofia Alexandra Gomes Anastácio
Degree in Biotechnology (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2014 - 2014 Effects of sitagliptin therapy on the evolution of pancreatic and renal lesions in type 2 diabetes - experimental study in the Zucker Diabetic Fatty rat
Orientador de Ana Cristina Pais Mega de Andrade
Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Post-doc Supervision - Relationship between chronic renal failure, inflammation and erythropoiesis in resistance to human recombinant erythropoietin therapy
Orientador de João Carlos Azevedo Cruz Gonçalves Fernandes
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Study of the regulation of the inflammatory response and endoplasmic reticulum stress by sitagliptin in the kidney of animals with type 2 diabetes
Coorientador de Catarina Isabel Rodrigues Marques
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2013 Characterization of risk factors for cardiovascular disease, in pre-diabetics and diabetics, in a population sample from Cova da Beira
Orientador de Diana Inês Mota Gaspar
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2012 - 2013 Conversion from cyclosporine to sirolimus in kidney transplantation - Is there renoprotection?
Orientador de Tiago João Neves Carvalho
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Role of hepcidin impairment in chronic kidney disease - implication for new therapeutics opportunities
Orientador de António Miguel Ferrão Silveira
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Renoprotective effects of direct renin inhibitors
Orientador de Joana Marques Martins Cardoso Silva
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Response to rhEPO therapy in situations of chronic versus severe renal failure in an experimental animal model
Orientador de Joana Sanches Pires
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Study of the prevalence of pre-diabetes and diabetes in a population sample from Cova da Beira. Characterization of risk factors
Orientador de Mariana Sofia Lambelho Elvas
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011 - 2012 Effects of Ciclosporin-A and Sirolimus on rat aorta vascular smooth muscle cells (A7R5)
Coorientador de Diogo António Gonçalves Candeias da Guerra Maio
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011 - 2012 Evaluation of the effect of ketamine and isoflurane in the long and medium term in animal models
Orientador de Laíse Figueiredo de Oliveira
Master in Public Health (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Early cardiac effects of a high-sucrose diet in a rat model of prediabetes
Orientador de Sara Raquel Nunes
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2012 Sucrose-induced memory deficits
Coorientador de Edna Filipa Pais Soares
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2012 Cardiorenal anemia syndrome in the elderly - cytoprotective effects of erythropoietin
Orientador de Paula Cristina Cruz Correia
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Preventive effect of omega-3 in the treatment of bladder carcinoma
Orientador de Raquel Sacramento Rosa Cerejo
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2011 Cardio-renal effects of immunomodulatory therapy
Orientador de Ana Marta Romão
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2011 Influence of genotype vs. paraoxonase 1 phenotype at risk of cardiovascular disease
Orientador de José Luis Lemos de Sá
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Pleiotropic effects of statistics and their interactions with anticoagulants and platelet antiaggregants
Orientador de Filipe Miguel Pereira Viera
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Recombinant human erythropoietin - therapeutic applications and illegal use in sport
Orientador de Maria João Lobato Cortesão Nobre
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 New and old vitamin D analogs as renoprotective therapy
Orientador de Rui Manuel Andrade Maia Tavares Moreira
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2010 Resistance to recombinant human erythropoietin therapy - studies in experimental models of anemia and chronic kidney disease.
Orientador de Ana Patrícia Amieiro Garrido
Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2010 Minimization of cyclosporine A-induced nephrotoxicity through sirolimus conversion protocols - Mechanisms and biomarkers in an animal model in rat
Orientador de José Vítor de Oliveira Sereno
Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The role of dexmedetomidine in anesthesia and intensive care
Orientador de Joana Isabel Afonso Coelho de Oliveira
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Cardio-renal effects of recombinant human erythropoietin (rhEPO) therapy in an animal model of chronic renal failure induced by nephrectomy
Orientador de Ana Margarida Teixeira
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2010 Pleiotropic effects of statins - Why the use of high doses of statins in post-myocardial infarction
Orientador de Filipe Torres Bento Sousa
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Role of inflammation in tumor development: therapeutic potential of COX2 inhibitors
Orientador de Daniel Luis Sebastião Costa
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Epidemiological study of a sample of the Portuguese population (municipality of Manteigas) - risk factors and non-pharmacological and drug therapy
Orientador de Luís Filipe Vicente Saraiva
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The use of statins in antineoplastic therapy - current context and future perspectives
Orientador de Hugo Miguel Moreira Aleixo
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The role of non-pharmacological therapy in the treatment of type 2 diabetes mellitus
Orientador de Luís Miguel Dos Santos Vieira
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2009 High density lipoprotein dysfunction and cardiometabolic risk - Relationship with other biomarkers
Orientador de Filipa Alexandra Mascarenhas Melo
Ciências Biomédicas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiovascular effects of intravenous anesthetics - current concerns and future perspectives
Orientador de Cláudia Raquel Marques Carreira
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Endocannabinoid system and cardiovascular therapy: new perspectives
Orientador de Pedro Miguel Oliveira Pinto Da Cunha
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Bladder carcinoma in an experimental animal model - Preventive / curative effect of a statin
Orientador de Ângela Filipa Fonseca Pinto
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2008 - 2009 Effect of sitagliptin in an animal model of type 2 diabetes mellitus - dysmetabolism, oxidative stress and inflammation
Orientador de Liliana Figueiredo Ferreira
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2008 - 2009 Bladder carcinoma - new pharmacological therapies for prevention and treatment
Orientador de Romeu Joel Fernandes Pinho
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Type 2 diabetes therapy with incretins
Orientador de Ricardo Godinho de Andrade
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 The cardio-renal anemia syndrome - pathophysiological bases and therapeutic perspectives of human recombinant erythropoietin
Orientador de Bruno Miguel dos Santos Pedro
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiovascular effects of immunosuppressive therapy
Orientador de Luís Filipe Pedro Moisão França
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 HDL as a target for therapeutic action in dyslipidemia
Orientador de Ricardo da Silva Vicente
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiometabolic effects of using rhEPO in an experimental doping model in sport.
Orientador de Nuno Miguel Torres Piloto de Albuquerque
Master in Forensic Medicine and Forensic Sciences (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2007 - 2008 Characterization of an animal model of renal failure - Evaluation of the effects of rhEPO treatment
Orientador de Ana Patrícia Amieiro Garrido
Master in Biochemistry (Mestrado)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2007 - 2008 Characterization of an animal model (wistar rat) of bladder carcinoma - Study of Celecoxib (Celebrex)
Orientador de José Vitor Oliveira Sereno
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2006 - 2007 Characterization of an Animal Model (Wistar rat) of bladder carcinoma - Sirolimus Study
Orientador de André Tiago Ribeiro Dias
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2005 - 2006 Study of the influence of aerobic exercise in Zucker Diabetty Fatty rats
Orientador de Ana Patrícia Amieiro Garrido
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2004 - 2005 Physical exercise and cardiovascular risk - comparative study of the effects of running and swimming
Orientador de Nuno Miguel Torres Piloto de Albuquerque
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2005 Effect of physical exercise on an animal model of type 2 diabetes
Orientador de Ana Sofia Simões Bento Baptista
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2002 - 2003 The peripheral serotonergic system and the thromboxane A2 / prostacyclin pathway in rats submitted to isosorbide 5-mononitrate to treat cyclosporine A-induced hypertension
Orientador de Luísa Margarida da Silva Ponte
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002 - 2003 Effect of Isosorbide 5-mononitrate on plasma and platelet contents of catecholamines in rats with cyclosporine A-induced hypertension
Orientador de Luís Gabriel Borges Rocha
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2021 - Atual Week of round table related to the theme "World Food Day" (2021)
Outro (Coorganizador)
2024/01/25 - 2024/01/26 V SPCAL Congress (Sociedade Portuguesa de Ciências em Animais de Laboratório | Portuguese Society of Laboratory Animal Sciences) (2024/01/25 - 2024/01/26)
Congresso (Presidente da Comissão Organizadora)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2023/02/01 - 2023/02/03 53rd Annual Meeting of the Portuguese Society of Pharmacology, 41st Clinical Pharmacology Meeting and 22nd Toxicology Meeting (2023/02/01 - 2023/02/03)
Congresso (Presidente da Comissão Organizadora)
Sociedade Portuguesa de Farmacologia, Portugal
2021/12/10 - 2021/12/10 1st SPCAL Scientific Day – Responsible Research and Innovation in Laboratory Animal Sciences (2021/12/10 - 2021/12/10)
Congresso (Membro da Comissão Organizadora)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2019/10/03 - 2019/10/04 Curso CRISH – Cocriação de soluções inovadoras para a saúde (2019/10/03 - 2019/10/04)
Outro (Presidente da Comissão Organizadora)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2018/11/15 - 2018/11/15 3rd National Symposium on Animal Welfare Bodies (AWBs)– “3Rs in action” (2018/11/15 - 2018/11/15)
Simpósio (Presidente da Comissão Organizadora)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017/02/02 - 2017/02/04 XLVII Annual Meeting of the Portuguese Society of Pharmacology, XXVI Clinical Pharmacology Meeting and XVII Toxicology Meeting (2017/02/02 - 2017/02/04)
Congresso (Membro da Comissão Organizadora)
Sociedade Portuguesa de Farmacologia, Portugal
2012/03/31 - 2012/03/31 Joint Meeting of the Portuguese Society of Hemorheology and Microcirculation and the Vascular Biology Center of the Portuguese Society of Angiology and Vascular Surgery (2012/03/31 - 2012/03/31)
Encontro (Presidente da Comissão Organizadora)
Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2011/02/02 - 2011/02/04 XLI Annual Meeting of the Portuguese Pharmacology Society XXIX Clinical Pharmacology Meeting and X Toxicology Meeting (2011/02/02 - 2011/02/04)
Congresso (Membro da Comissão Organizadora)
Sociedade Portuguesa de Farmacologia, Portugal
2005/11/26 - 2005/11/26 XVI Annual Meeting of the Portuguese Society of Hemorheology and Microcirculation (2005/11/26 - 2005/11/26)
Encontro (Membro da Comissão Organizadora)
Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2003/12/04 - 2003/12/06 XXXIV Annual Meeting of the Portuguese Pharmacology Society (2003/12/04 - 2003/12/06)
Congresso (Membro da Comissão Organizadora)
Sociedade Portuguesa de Farmacologia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020 - 2020 Food & Function (2042-650X) The Royal Society of Chemistry
2020 - 2020 EBioMedicine (2352-3964) Elsevier
2017 - 2020 Nutrients (2072-6643) MDPI AG
2019 - 2019 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (0925-4439) Elsevier
2019 - 2019 Frontiers in Pharmacology (1663-9812) Frontiers Media SA
2019 - 2019 Frontiers in Physiology (1664-042X) Frontiers Media SA
2019 - 2019 Obesity Medicine (2451-8476) Elsevier
2019 - 2019 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2018 - 2019 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2017 - 2019 Brain Behavior and Immunity (1090-2139) Elsevier
2016 - 2019 Revista Portuguesa de Cardiologia (0870-2551) Elsevier
2018 - 2018 Disease Models & Mechanisms (1754-8411) The Company of Biologists
2018 - 2018 Journal of Biological Regulators and Homeostatic Agents
2018 - 2018 Journal of Diabetes Research (2314-6753) Hindawi Limited
2018 - 2018 Life Sciences (0024-3205) Elsevier
2018 - 2018 Neuroscience Letters (0304-3940) Elsevier
2018 - 2018 Phytotherapy Research (1099-1573) Wiley (John Wiley & Sons)
2017 - 2018 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2016 - 2018 Kidney and Blood Pressure Research (1423-0143) S. Karger AG
2015 - 2018 International Journal of Biological Sciences (1449-2288) Ivyspring International Publisher
2014 - 2018 British Journal of Pharmacology (1476-5381) Wiley (Blackwell Publishing)
2017 - 2017 Antioxidants
2017 - 2017 Bioscience Reports (1573-4935) Portland Press
2017 - 2017 Brain Research (0006-8993) Elsevier
2017 - 2017 Brazilian Journal of Pharmaceutical Sciences (1984-8250) SciELO
2017 - 2017 Cellular Physiology and Biochemistry (1421-9778) Cell Physiol Biochem Press GmbH and Co KG
2017 - 2017 Evidence-based Complementary and Alternative Medicine (1741-4288) Hindawi Limited
2017 - 2017 Food and Chemical Toxicology (0278-6915) Elsevier
2017 - 2017 Food Research International (0963-9969) Elsevier
2017 - 2017 Fundamental and Clinical Pharmacology (1472-8206) Wiley (Blackwell Publishing)
2017 - 2017 Heart and Vessels (1615-2573) Springer-Verlag
2017 - 2017 Journal of International Medical Research (1473-2300) SAGE Publications
2017 - 2017 Marine Drugs (1660-3397) MDPI AG
2017 - 2017 Mediators of Inflammation (1466-1861) Hindawi Limited
2017 - 2017 Medicines (2305-6320) MDPI AG
2017 - 2017 Pharmacology
2017 - 2017 Toxicology and Applied Pharmacology (1096-0333) Elsevier
2016 - 2017 Biomedicine & Pharmacotherapy (0753-3322) Elsevier
2016 - 2017 Current Medicinal Chemistry (0929-8673) Bentham Science
2016 - 2017 Scientific Reports (2045-2322) Springer Science and Business Media LLC
2013 - 2017 Obesity Reviews (1467-789X) Wiley (Blackwell Publishing)
2012 - 2017 PLoS ONE (1932-6203) Public Library of Science
2011 - 2017 Cardiovascular Diabetology (1475-2840) Springer (Biomed Central Ltd.)
2010 - 2017 Acta Urológica Portuguesa (2387-0419) Associacao Portuguesa de Urologia
2016 - 2016 Acta Diabetologica (1432-5233) Springer-Verlag
2016 - 2016 Basic & Clinical Pharmacology & Toxicology (1742-7843) Wiley (Blackwell Publishing)
2016 - 2016 Canadian Journal of Physiology and Pharmacology (1205-7541) Canadian Science Publishing
2016 - 2016 Cell Proliferation (1365-2184) Wiley (Blackwell Publishing)
2016 - 2016 Ciência & Saúde Coletiva (1413-8123) SciELO
2016 - 2016 Current Drug Safety (1574-8863) Bentham Science
2016 - 2016 Drug Delivery (1521-0464) Informa UK (Taylor & Francis)
2016 - 2016 European Journal of Inflammation (1721-727X) SAGE Publications
2016 - 2016 Human Psychopharmacology Clinical and Experimental (1099-1077) Wiley (John Wiley & Sons)
2016 - 2016 Journal of Cardiovascular Pharmacology and Therapeutics (1940-4034) SAGE Publications
2016 - 2016 Journal of Science and Medicine in Sport (1440-2440) Elsevier
2016 - 2016 Journal of Vascular Research (1423-0135) S. Karger AG
2016 - 2016 Medical Science Monitor (1643-3750) "International Scientific Information, Inc."
2016 - 2016 Pediatric Research (1530-0447) Springer Science and Business Media LLC
2016 - 2016 Pharmacological Reports (2299-5684) Springer-Verlag
2016 - 2016 Reproductive Biology (1642-431X) Elsevier
2015 - 2016 Journal of Diabetes and its Complications (1056-8727) Elsevier
2015 - 2016 Toxicology
2015 - 2015 African Health Sciences
2015 - 2015 Biomarkers (1366-5804) Informa UK (Taylor & Francis)
2015 - 2015 Boletim da Sociedade Portuguesa de Hemorreologia e Microcirculação
2015 - 2015 Cancer Biomarkers (1875-8592) IOS Press
2015 - 2015 Cell Biology International (1095-8355) Wiley (John Wiley & Sons)
2015 - 2015 Diabetes (0012-1797) American Diabetes Association
2015 - 2015 Drug Development and Industrial Pharmacy (1520-5762) Informa UK (Taylor & Francis)
2015 - 2015 Food Chemistry (0308-8146) Elsevier
2015 - 2015 International Journal of Environmental Research and Public Health (1660-4601) MDPI AG
2015 - 2015 International Journal of Immunopathology and Pharmacology (0394-6320) SAGE Publications
2015 - 2015 Journal of Cellular and Molecular Medicine (1582-4934) Wiley (Blackwell Publishing)
2015 - 2015 Journal of Clinical Medicine
2015 - 2015 Journal of Hematology & Thromboembolic Diseases (2329-8790) OMICS Publishing Group
2015 - 2015 Journal of Physiology and Biochemistry (1877-8755) Springer-Verlag
2015 - 2015 Journal of Applied Toxicology (1099-1263) Wiley (John Wiley & Sons)
2015 - 2015 Journal of Transplantation Technologies & Research (2161-0991) OMICS Publishing Group
2015 - 2015 Leukemia (1476-5551) Springer Science and Business Media LLC
2015 - 2015 Molecular Nutrition & Food Research (1613-4133) Wiley (John Wiley & Sons)
2015 - 2015 Ophthalmic Research (1423-0259) S. Karger AG
2015 - 2015 Pediatric Exercise Science (1543-2920) Human Kinetics
2015 - 2015 Redox Report (1351-0002) Maney Publishing
2015 - 2015 SpringerPlus (2193-1801) Springer (Biomed Central Ltd.)
2014 - 2015 Millenium - Journal of Education Technologies and Health (1647-662X) Instituto Politecnico de Viseu
2013 - 2015 Diabetology & Metabolic Syndrome (1758-5996) Springer (Biomed Central Ltd.)
2012 - 2015 International Journal of Molecular Sciences (1422-0067) MDPI AG
2009 - 2015 Kidney International (1523-1755) Elsevier
2014 - 2014 Aging and Disease (2152-5250) Aging and Disease
2014 - 2014 BioMed Research International (2314-6141) Hindawi Limited
2014 - 2014 Biomedical & Pharmacology Journal (2456-2610) Oriental Scientific Publishing Company
2014 - 2014 Endocrine Metabolic & Immune Disorders - Drug Targets (1871-5303) Bentham Science
2014 - 2014 Expert Review of Endocrinology & Metabolism (1744-8417) Informa UK (Taylor & Francis)
2014 - 2014 Inflammation (1573-2576) Springer-Verlag
2014 - 2014 JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (0973-709X) JCDR Research and Publications
2014 - 2014 Journal of Separation Science (1615-9314) Wiley (John Wiley & Sons)
2014 - 2014 Korea-Australia Rheology Journal (2093-7660) Springer-Verlag
2014 - 2014 Quality of Life Research (1573-2649) Springer-Verlag
2013 - 2013 Anais da Academia Brasileira de Ciências (0001-3765) SciELO
2013 - 2013 British Journal of Medicine and Medical Research (2231-0614) Sciencedomain International
2013 - 2013 European Journal of Sport Science (1746-1391) Informa UK (Taylor & Francis)
2013 - 2013 Journal of Diabetes & Metabolic Disorders (2251-6581) Springer (Biomed Central Ltd.)
2013 - 2013 Journal of Drug Metabolism & Toxicology (2157-7609) OMICS Publishing Group
2013 - 2013 SAGE Open Medicine (2050-3121) SAGE Publications
2012 - 2013 BMC Nephrology (1471-2369) Springer (Biomed Central Ltd.)
2011 - 2013 Forensic Science International (0379-0738) Elsevier
2010 - 2013 American Journal of Nephrology
2010 - 2013 Clinical and Experimental Pharmacology and Physiology (1440-1681) Wiley (Blackwell Publishing)
2012 - 2012 Annals of Nutrition and Metabolism (1421-9697) S. Karger AG
2012 - 2012 Blood Cells Molecules and Diseases (1096-0961) Elsevier
2012 - 2012 Diabetes and Vascular Disease Research (1752-8984) SAGE Publications
2012 - 2012 Disease Markers (1875-8630) Hindawi Limited
2012 - 2012 Endocrine (1559-0100) Springer-Verlag
2012 - 2012 iConcept Press
2012 - 2012 Journal of Endocrinology (1479-6805) Bioscientifica
2012 - 2012 Journal of Pharmacology and Pharmacotherapeutics (0976-500X) Medknow Publications
2012 - 2012 Molecular and Cellular Biochemistry (1573-4919) Springer-Verlag
2012 - 2012 Molecular and Cellular Endocrinology (0303-7207) Elsevier
2012 - 2012 QJM (1460-2393) Oxford University Press
2012 - 2012 Resuscitation (0300-9572) Elsevier
2012 - 2012 Scandinavian Journal of Urology and Nephrology (1651-2065) Informa UK (Taylor & Francis)
2010 - 2012 Journal of Pharmacy And Bioallied Sciences (0975-7406) Medknow Publications
2008 - 2012 Renal Failure (1525-6049) Informa UK (Taylor & Francis)
2011 - 2011 Blood Purification (1421-9735) S. Karger AG
2011 - 2011 Chronicles of Young Scientists (2229-5186) Medknow Publications
2011 - 2011 Experimental Biology and Medicine (1535-3699) SAGE Publications
2011 - 2011 Journal of Forensic and Legal Medicine (1752-928X) Elsevier
2011 - 2011 Neuropharmacology (0028-3908) Elsevier
2011 - 2011 Obesity Facts (1662-4033) S. Karger AG
2010 - 2011 American Journal of Hypertension (1941-7225) Oxford University Press
2010 - 2011 Hemodialysis International (1542-4758) Wiley (Blackwell Publishing)
2009 - 2011 Nephrology (1440-1797) Wiley (Blackwell Publishing)
2010 - 2010 African Journal of Pharmacy and Pharmacology (1996-0816) Academic Journals
2010 - 2010 British Journal of Cancer (1532-1827) Springer Science and Business Media LLC
2010 - 2010 Journal of Cancer Biology and Therapeutics (2379-5972) Gratis Open Access Publishers LLC
2010 - 2010 International Immunopharmacology (1567-5769) Elsevier
2010 - 2010 Nefrología (0211-6995) Elsevier
2010 - 2010 Pharmacological Research (1096-1186) Elsevier
2010 - 2010 The Tohoku Journal of Experimental Medicine (1349-3329) Tohoku University Medical Press
2009 - 2010 Toxins (2072-6651) MDPI AG
2009 - 2009 Archives of Medical Research (0188-4409) Elsevier
2009 - 2009 Journal of Pancreas
2009 - 2009 Nephrology Dialysis Transplantation (1460-2385) Oxford University Press
2009 - 2009 The Open Drug Discovery Journal (1877-3818) Bentham Science
2008 - 2008 The Open Clinical Chemistry Journal (1874-2416) Bentham Science
2007 - 2008 Transplantation (0041-1337) Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2023 - 2023 Invited reviewer to evaluate PhD proposals in 2023 for FCT in the panel of Clinical Medicine and Health Sciences
Membro
FCT - Fundação para a Ciência e Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2022 - 2022 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme NRP 79 (2022) - Swiss National Science Foundation (SNSF) (SWITZERLAND)
Avaliador
Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Suiça Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2021 - 2021 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme Appel à Projets Résilience COVID-19 (2021)- Agence Nationale de la Recherche (ANR) ¿ (FRANCE) Agence nationale de la recherche, França
2020 - 2020 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Programme Clinical Research (KLIF) 2020 - Austrian Science Fund (FWF)
Avaliador
Fonds zur Förderung der wissenschaftlichen Forschung, Áustria Fonds zur Förderung der wissenschaftlichen Forschung
2020 - 2020 Invited Reviewer to evaluate reserch proposals of proposals for Competitive Funding - PRIN: Progetti di ricerca di rilevante interesse nazionale ¿ Bando 2020 - Italian Ministry of University and Research (MUR) - (ITALY)
Avaliador
Italian Ministry of University and Research, Itália Italian Ministry of University and Research
2016 - 2016 Invited Reviewer for Evaluation of proposals for Competitive Funding - RD Lawrence Fellowship full application 2016 - Diabetes UK
Avaliador
Diabetes UK
2004 - 2016 Evaluation Committee of the FMUC for the Integrated Performance Evaluation System of Public Administration (SIADAP)
Membro
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2015 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme CE17 2015 - Recherche translationnelle en Santé - Agence Nationale de la Recherche (ANR) – (FRANCE)
Avaliador
Agence nationale de la recherche
2013 - 2013 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Grant Proposal for the 2013 National Research Funding Competition - Superior Council of the National Fund for Scientific & Technological Development – (CHILE)
Avaliador
Superior Council of the National Fund for Scientific & Technological Development – (Chile)
2009 - 2009 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Grant Proposal in Bio-Medical SPA Research 2009 Fondazione per la Ricerca Scientifica Termale (FoRST) (ITALY)
Avaliador
Fondazione per la Ricerca Scientifica Termale (FoRST) – (Italy)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2024 - Atual Advanced Course in Tissue Barriers in Health and Disease Doctoral Programme in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2023 - Atual Advanced Courses "One Health" Doctoral Program in Experimental Biology and Biomedicine (BEB) (Doutoramento) Universidade de Coimbra, Portugal
2022 - Atual Hot Topics in Medicine Mestrado em Química Medicinal (Mestrado) Universidade de Coimbra, Portugal
2022 - Atual Clinical and Forensic Toxicology Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Atual Toxicity and Disease Master's degree in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022 - Atual Natural Bioactive Compounds Master Degree in Applied Pharmacotherapy (Mestrado) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2022 - Atual “Participatory praxis in healthy aging research: Why and how should we get involved?" European Doctoral School of Aging Eit Health (Doctorat) EIT Health, Alemanha
2021 - Atual Societal Challenges Degree in Biology (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020 - Atual Efficacy and Safety of Natural Products Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2020 - Atual Biology of Nutrition Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2020 - Atual Laboratory Rotations Master degree in Biochemistry (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020 - Atual Pharmacology II Master degree in Medicinal Chemistry (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - Atual Seminars Doctoral Program in Experimental Biology and Biomedicine (BEB) (Doutoramento) Universidade de Coimbra, Portugal
2018 - Atual Animal Experimentation Advanced Course Doctoral Program in Health Sciences (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - Atual Cardiovascular Sciences Advanced Course Doctoral Program in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2018 - Atual Pharmacology II Degree in Medicinal Chemistry (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - Atual Research Seminars Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017 - Atual Research Methodologies and Techniques Master in Biomedical Research (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017 - Atual Thematic Seminars Master in Applied Pharmacology (Mestrado) FFUC - Faculdade de Farmácia da Universidade Coimbra, Portugal
2017 - Atual Biotoxicology Master Degree in Food Quality and Technology (Mestrado) Instituto Politécnico de Viseu Escola Superior Agrária de Viseu, Portugal
2017 - Atual Research Methods and Techniques Advanced Course Doctoral Program in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2016 - Atual Applied Research Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2016 - Atual Laboratory Rotations Master in Biomedical Research (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2011 Therapeutics (I and II) Degree in Medicine (Licenciatura) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2011 Clinical Pharmacology and Toxicology Degree in Medicine (Licenciatura) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2010 Pharmacology Degree in Health Technologies (Licenciatura) Universidade Católica Portuguesa Escola Superior Politécnica de Saúde Porto, Portugal
2007 - 2010 Quality Control and Pharmacovigilance Degree in Health Technologies (Licenciatura) Universidade Católica Portuguesa Escola Superior Politécnica de Saúde Porto, Portugal

Membro de associação

Nome da associação Tipo de participação
2022 - Atual VICE-PRESIDENT of EXECUTIVE BOARD of Portuguese Society of Pharmacology
2021 - Atual MEMBER OF EXECUTIVE BOARD - Portuguese Society of Laboratory Animal Sciences (SPCAL)
2020 - Atual VICE-PRESIDENT OF EXECUTIVE BOARD - Portuguese Society of Atherosclerosis
2020 - Atual VICE-PRESIDENT of EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation
2019 - Atual SECRETARY OF GENERAL ASSEMBLY - Portuguese Society of Pharmacology General Assembly (Secretary)
2012 - Atual European Federation for the Study Diabetes (EFSD)
2012 - Atual European Society of Atherosclerosis (EAS)
2012 - Atual European Renal Association - European Dialysis and Transplant Association (ERA-EDTA)
2010 - Atual Sociedade Portuguesa de Diabetologia
2008 - Atual Sociedade Portuguesa de Ciências em Animais de Laboratório
2000 - Atual Sociedade Portuguesa de Hemorreologia e Microcirculação (SPHM) Membro (desde 2000), Direção (desde 2006) e Vice-Presidente (desde 2020)
1998 - Atual Sociedade Portuguesa de Farmacologia Membro (desde 1998), Secretário da AG (2019-2022) e Vice-Presidente (2022-2024)
2005 - 2023 Sociedade Portuguesa de Aterosclerose Membro (desde 2005), Direção (2017-2020) e Vice-Presidente (2020-2023)
2006 - 2018 SECRETARY OF EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation 2006-2008 | 2012-2014 | 2014-2016 | 2016-2018
2011 - 2013 MEMBER OF FISCAL COUNCIL - Portuguese Society of Atherosclerosis Conselho Fiscal (Vogal)
2008 - 2010 TRESOURER of EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2019 - Atual Doctoral Thesis Monitoring Committee - INTERUNIVERSITY DOCTORAL PROGRAM IN AGING AND CHRONIC DISEASES, a partnership between UC, Universidade Nova de Lisboa and Universidade do Minho.
Membro
Universidade do Minho Escola de Medicina, Portugal
2016 - Atual Doctoral Monitoring Committee - DOCTORAL PROGRAM IN HEALTH SCIENCES - Faculty of Medicine from University of Coimbra
Membro
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - Atual Editorial Board of PORTUGUESE JOURNAL OF NEPHROLOGY AND HYPERTENSION
Membro
2011 - Atual Editorial Board of ACTA UROLÓGICA PORTUGUESA
Membro
2010 - Atual Editorial Board of CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Membro
2020 - 2020 Workgroup for the EUROPEAN CERTIFIED PHARMACOLOGIST PROGRAM on behalf of Portuguese Society of Pharmacology
Membro
Sociedade Portuguesa de Farmacologia, Portugal
2015 - 2018 Editorial Board of SPRINGER PLUS
Membro

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2017 - 2017 Discussion of Seminar I on the Doctoral Thesis Project in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra PhD Student: Helena Maria da Silva Leal Thesis: Sirtuin 2 as a new target to revert metabolic dysfunction Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Discussion of the PhD Thesis Project in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra PhD student: Jorge M. Alves Silva Thesis: An innovative approach to the treatment of pulmonary arterial hypertension using plant extracts encapsulated in extracellular vesicles Universidade de Coimbra Faculdade de Farmácia, Portugal
2013 - 2013 External Evaluator of the Seminar on Doctorate in Medicine and Life Sciences at the Faculty of Medical Sciences - Universidade Nova de Lisboa PhD student: Inês Raquel Claro Aires Thesis: Development of a cellular model for familial renal glucosuria: evaluation of mutants and implications for the treatment of type 2 diabetes mellitus Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinções

Prémio

2023 Prémio Orlando Leitao - Best oral communication
Sociedade Portuguesa de Neurologia, Portugal
2023 Menção Honrosa do Prémio Pedro Eurico Lisboa - Best paper in diabetes in 2022
Sociedade Portuguesa de Diabetologia, Portugal
2023 Melhor poster em investigação fundamental
Sociedade Portuguesa de Diabetologia, Portugal
2023 Melhor comunicação oral em investigação fundamental
Sociedade Portuguesa de Diabetologia, Portugal
2021 Refinement Prize 2021 - European Partnership for Alternatives to Animal testing (EPAA)
European Partnership for Alternatives to animal testing (EPAA), Bélgica
2021 Bolsa Pereira Monteiro de Apoio à Investigação Translacional em Neurologia
Sociedade Portuguesa de Neurologia, Portugal

Outra distinção

2022 Travel Grant for participation in the 15th FELASA Congress (2022)
FELASA - Federation of European Laboratory Animal Sciences Associations, Bélgica
2022 Projetos de Ignição e Provas de Conceito INOVC+
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal

Universidade de Coimbra, Portugal
2020 Travel Grant for participation in the 88th EAS Meeting
European Atherosclerosis Society, Suécia
2019 Travel Grant for participation in the 87th EAS Meeting
European Atherosclerosis Society, Suécia
2018 Bolsa de Investigação - Melhor projecto de investigação na área da Urologia
Associação Portuguesa de Urologia | Jaba Recordati , Portugal
2018 Prémio de Boas Práticas de Envelhecimento Ativo e Saudável - Categoria Conhecimento+ (Edição 2018)
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal

Ageing@Coimbra, Portugal
2017 Bolsa Emílio Peres da Sociedade Portuguesa de Diabetologia 2017 – ao melhor projecto de investigação na área da nutrição
Sociedade Portuguesa de Diabetologia, Portugal
2017 Menção Honrosa para comunicação oral apresentada no XXV Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2017 Bolsa de Ignição do projeto INOV C 2020
Universidade de Coimbra, Portugal
2017 Top 1% Peer Review Award - Multidisciplinary
PUBLONS, Estados Unidos
2016 Prémio para melhor projecto de investigação na área da diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2016 Prémio Orlando Leitão/Biogen 2016 - melhor comunicação orais do congresso
Sociedade Portuguesa de Neurologia, Portugal
2015 Travel Grant para participação no FEBS Young Scientists Forum
Federation of European Biochemical Societies, Reino Unido
2015 Prémio Bayer - Melhor comunicação oral apresentada na Reunião de Primavera-Verão do Grupo de Estudos de Esclerose Múltipla
2015 Travel Grant para participação no 4th European Congress of Immunology
European Federation of Immunological Societies, Países Baixos
2015 Prémio para melhor comunicação oral na área de Neurosciences and autoimmunity apresentada no UMIB SUMMIT 2015
2015 Menção honrosa para trabalho de investigação no âmbito do Prémio de Investigação Científica Professora Doutora Maria Odette Santos-Ferreira
Ordem dos Farmaceuticos, Portugal
2015 Prémio para melhor apresentação oral “Rapid-fire posters” na área “New techniques in Bioimaging” no VII Meeting Anual do IBILI
2014 One of the Best Abstracts for Young Scientists in the ERa-EDTA Congress 2014 (Amsterdam)
European Renal Association European Dialysis and Transplant Association, Itália
2014 Best poster presentation - XVIII Congress da Sociedade Portuguesa de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2014 Prémio Ana Maria Correia - Melhor projecto de investigação científica na área da transplantação
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia, Portugal
2013 Menção Honrosa para comunicação oral na área da diabetes experimental apresentada na Reunião Anual da Sociedade Portuguesa de Diabetologia 2013
Sociedade Portuguesa de Diabetologia, Portugal
2013 Prémio para projecto de investigação na área da diabetes no âmbito do Grupo de Investigação Fundamental e Translacional (GIFT)
Sociedade Portuguesa de Diabetologia, Portugal
2013 Bolsa para trabalho de investigação - GAI da FMUC
Universidade de Coimbra Faculdade de Medicina, Portugal
2013 Uro-Oncology Grant 2013 - Melhor trabalho na área da uro-oncologia
Astellas European Foundation, Reino Unido
2013 Melhor trabalho de investigação - Congresso Anual da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2013 Melhor trabalho de investigação - Congresso da Sociedade Portuguesa de Diabetologia
Sociedade Portuguesa de Diabetologia, Portugal
2013 Travel Grant for the 15th International Congress of Immunology
European Federation of Immunological Societies, Países Baixos
2012 Best Scientific Oral Presentation - Basic Science
Sociedade Portuguesa de Nefrologia, Portugal
2012 Melhor trabalho em Investigação Básica - Encontro Renal 2012
Sociedade Portuguesa de Nefrologia, Portugal
2012 One of the Best Abstracts presented by young authors at the 49th Congress of ERA-EDTA
European Renal Association European Dialysis and Transplant Association, Itália
2012 Oral presentation Travel Award for the 20th Meeting of the EAU Section of Urological Research, Strasbourg
European Association of Urology, Países Baixos
2012 Melhor comunicação oral de “Health Surveillance” apresentada na Conferência CEF 2012
2012 Melhor projecto de investigação na área da Urologia
Associação Portuguesa de Urologia, Portugal
2011 Best Scientific presentation - 5º Congresso Português de Hipertensão
Sociedade Portuguesa de Hipertensão, Portugal
2011 Best research project in diabetes - Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2011 Best Scientific Oral Presentation - Basic Science - XII Congresso Português de Endocrinologia
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2011 Best Original Study in Nephrology - Prémio ROCHE
Sociedade Portuguesa de Nefrologia, Portugal
2011 Best research project in Urology - Congresso da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2011 Best Scientific presentation - XIX Congresso Nacional de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2010 Best Poster with oral presentation - Prémio EDOL
Sociedade Portuguesa de Dermatologia e Venereologia, Portugal
2010 Best Scientific Oral Presentation - XII Congresso Português de Endocrinologia
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2010 Honorable Mention on Clinical investigation
2010 Best research project in Urology - Reunião Anual da Sociedade Portuguesa de Transplantação
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia, Portugal
2010 Best research project in Multiple Sclerosis
Grupo de Estudos de Esclerose Múltipla | Merck Serono, Portugal
2009 Best scientific work - Pfizer Price in Oncologic Urology
European Organisation for Research and Treatment of Cancer, Bélgica
2009 Best Scientific Oral Comunication - 17º Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2009 Best research project in Urology - Congresso da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2008 Best Scientific Oral Comunication - 16º Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2008 Honorable Mention for best research project in Urology
Associação Portuguesa de Urologia, Portugal
2006 Best scientific oral presentation - XIV Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2004 Best Scientific Research Communication - 6º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2004 Best oral presentation - XXIV Congresso da SPOT
Sociedade Portuguesa de Ortopedia e Traumatologia, Portugal
2004 Best research project in Urology - Prémio Jaba Recordati
Associação Portuguesa de Urologia, Portugal
2001 Best Scientific Comunication - Prémio Merk Farma & Química
Sociedade Portuguesa de Aterosclerose, Portugal