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Pertovaara Antti. Completed the Postgraduate Certificate in Medical doctor (M.D.) 1978 and PhD 1982 in University of Helsinki. Postdoctoral training at University of Michigan, USA (1986-87), University of Heidelberg, Germany (1991-92) and Harvard Medical School, USA (2001-02). Main research interest is neurobiology of pain. Currently Professor of Physiology and Head of Department in the Faculty of Medicine, University of Helsinki. Published over 250 original articles in peer-reviewed journals, and h-index is 48 (Web of Science). Has over 10 section(s) of books. Supervised/Co-supervised 16 completed PhD theses. Currently in the editorial board of 4 journals (PAIN, European Journal of Pain, Scandinavian Journal of Pain, European Journal of Pharmacology). From the FCT point of view, it is noteworthy that Pertovaara laboratory in Helsinki has a long and successful collaboration with University of Minho in Braga, Portugal. Since 2004, five Portuguese doctoral students from the University of Minho have done (neurophysiological) part of their Ph.D. work in Helsinki at the laboratory of prof. Antti Pertovaara. These doctoral students who all have completed their PhDs at the University of Minho are Hugo Leite-Almeida, Filipa Pinto-Ribeiro, M Leonor Barbosa Goncalves, Diana Amorim, and Ana David-Pereira. Pertovaara was a co-supervisor for one of these PhD Theses (M Leonor B Goncalves), and member of the Thesis committee for all other PhD Theses. Moreover, this collaboration between Pertovaara lab and University of Minho has resulted in 17 joint original publications in peer-reviewed international journals.
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Identificação

Identificação pessoal

Nome completo
Pertovaara Antti

Nomes de citação

  • Antti, Pertovaara

Identificadores de autor

Ciência ID
1B1A-8BAD-F2F5
ORCID iD
0000-0002-8590-7220

Telefones

Telemóvel
  • (+358) 407607123 (Profissional)

Moradas

  • Dept. Physiology, Haartmaninkatu 8 (POB 63), 00014, Helsinki, Helsinki, Finlândia (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Finlandês (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Alemão Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1) Utilizador proficiente (C1)
Sueco Utilizador independente (B2) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
1982
Concluído
 Physiology (Doktor (PhD))
Helsingin yliopisto, Finlândia
1972 - 1978
Concluído
 Medical doctor (M.D.) (Postgraduate Certificate)
Helsingin yliopisto Lääketieteellinen tiedekunta, Finlândia
Percurso profissional

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2004 - Atual Professor of Physiology Helsingin yliopisto Lääketieteellinen tiedekunta, Finlândia
1993 - 2004 Professor of Physiology Turun yliopisto Biolääketieteen laitos, Finlândia
Turun yliopisto Biolääketieteen laitos, Finlândia
1986 - 1992 Senior Lecturer in Physiology Helsingin yliopisto, Finlândia
Helsingin yliopisto, Finlândia
Projetos

Bolsa

Designação Financiadores
2018/01 - 2022/08 Facilitation of neuropathic pain by the amygdala: oxidative stress as culprit and cortical stimulation as treatment
315043
105709
111699
 Suomen Akatemia
2011/01 - 2014/12 TRPA1 ion channel in peripheral neuropathy, central pain hypersensitivity and neurogenic inflammation
137795
 Suomen Akatemia
2005/01 - 2007/12 Striatal dopamine D2 receptors in induction, maintenance, and modulation of pathophysiological pain
106804
 Suomen Akatemia
2004/01 - 2007/12 A mechanism-based development of selective treatments for pathophysiological pain
213425
 Suomen Akatemia
2002/01 - 2005/12 Patofysiologista kipua ylläpitävän säätöpiirin synapsi- ja ionikanavamekanismi
78582
213423
 Suomen Akatemia
2003/01 - 2004/12 Synaptic and ionic channel mecanisms underlying a pathophysiological pain control circuitry
204451
 Suomen Akatemia
1987/07 - 1987/12 NEURONAL ACTIVITY
F05TW003798
 John E Fogarty International Center

Projeto

Designação Financiadores
2012 - 2013 Descending histaminergic regulation of neuropathic pain
n/a
Orientador
Helsingin yliopisto, Finlândia
 Abbott Laboratories
Concluído
Produções

Publicações

Artigo em conferência
  1. Hugo Leite-Almeida; Antti Yrjö Pertovaara; Armando Almeida. "Emotional and cognitive impairments in experimental neuropathies". 2013.
  2. Leonor Gonçalves; Nora Bourbia; Hanna Viisanen; Osei Bonsu Ansah; Armando Almeida; Antti Yrjö Pertovaara. "Amygdala in the control of neuropathic pain". 2013.
  3. M M Heinricher; Antti Yrjö Pertovaara; M H Ossipov. "Descending modulation after injury". 2003.
Artigo em jornal
  1. Antti Yrjö Pertovaara. "Una analisi dei meccanismi del dolore", KOS : Rivista di scienza e etica., 1992, https://tuhat.helsinki.fi/portal/en/publications/una-analisi-dei-meccanismi-del-dolore(56335470-a687-41d4-89fa-ba889554cab3).html.
  2. Antti Yrjö Pertovaara. "Miksi tunnemme kipua?", Terveys 2000, 1988, https://tuhat.helsinki.fi/portal/en/publications/miksi-tunnemme-kipua(e9ea4029-131e-49a2-a206-401ea9856cdf).html.
  3. Antti Yrjö Pertovaara. "Arkisetkin tekijät muuntelevat kipua", Fysioterapia, 1986, https://tuhat.helsinki.fi/portal/en/publications/arkisetkin-tekijat-muuntelevat-kipua(d48b96ab-2201-4b70-8596-4be35da142df).html.
Artigo em revista
  1. Jing Lei; Gang Ye; Antti Pertovaara; Hao-Jun You. "Effects of Intramuscular Heating-needle Stimulation in Controlling Adjuvant-induced Muscle Nociception in Rats: Differential Roles of Thalamic Purinergic P2X3 Receptors". Neuroscience 433 (2020): 81-93. https://doi.org/10.1016/j.neuroscience.2020.02.039.
    10.1016/j.neuroscience.2020.02.039
  2. Gao Z; Wei H; Chen Z; Jalava N; Koivisto A; Pertovaara A. "Ongoing pain in streptozotocin model of diabetes in the rat: correlation with cutaneous cheminociception.". Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (2019): http://europepmc.org/abstract/med/32203940.
    10.26402/jpp.2019.6.14
  3. Zuyue Chen; Hong Wei; Boriss Sagalajev; Ari Koivisto; Antti Pertovaara. "Amygdaloid administration of tetrapentylammonium attenuates development of pain and anxiety-like behavior following peripheral nerve injury". Pharmacological Reports 71 1 (2019): 54-60. https://doi.org/10.1016/j.pharep.2018.08.005.
    10.1016/j.pharep.2018.08.005
  4. Ari Koivisto; Niina Jalava; Raymond Bratty; Antti Pertovaara. "TRPA1 Antagonists for Pain Relief". Pharmaceuticals (2018): https://doi.org/10.3390/ph11040117.
    10.3390/ph11040117
  5. Martikainen IK; Hagelberg N; Jääskeläinen SK; Hietala J; Pertovaara A. "Dopaminergic and serotonergic mechanisms in the modulation of pain: In vivo studies in human brain.". European journal of pharmacology (2018): http://europepmc.org/abstract/med/30036531.
    10.1016/j.ejphar.2018.07.038
  6. Bourbia N; Pertovaara A. "Involvement of the periaqueductal gray in the descending antinociceptive effect induced by the central nucleus of amygdala.". Physiological research (2018): http://europepmc.org/abstract/med/29750883.
    10.33549/physiolres.933699
  7. Chen Z; Wei H; Pertovaara A; Wang J; Carlson S. "Anxiety- and activity-related effects of paracetamol on healthy and neuropathic rats.". Pharmacology research & perspectives (2018): http://europepmc.org/abstract/med/29417759.
    10.1002/prp2.367
  8. Sagalajev B; Wei H; Chen Z; Albayrak I; Koivisto A; Pertovaara A. "Oxidative Stress in the Amygdala Contributes to Neuropathic Pain.". Neuroscience (2017): http://europepmc.org/abstract/med/29274353.
    10.1016/j.neuroscience.2017.12.009
  9. Gogulski J; Zetter R; Nyrhinen M; Pertovaara A; Carlson S. "Neural Substrate for Metacognitive Accuracy of Tactile Working Memory.". Cerebral cortex (New York, N.Y. : 1991) (2017): http://europepmc.org/abstract/med/28968804.
    10.1093/cercor/bhx219
  10. Lei J; Ye G; Wu JT; Pertovaara A; You HJ. "Role of capsaicin- and heat-sensitive afferents in stimulation of acupoint-induced pain and analgesia in humans.". Neuroscience (2017): http://europepmc.org/abstract/med/28684276.
    10.1016/j.neuroscience.2017.06.051
  11. Lamusuo S; Hirvonen J; Lindholm P; Martikainen IK; Hagelberg N; Parkkola R; Taiminen T; et al. "Neurotransmitters behind pain relief with transcranial magnetic stimulation - positron emission tomography evidence for release of endogenous opioids.". European journal of pain (London, England) (2017): http://europepmc.org/abstract/med/28493519.
    10.1002/ejp.1052
  12. Boriss Sagalajev; Hanna Viisanen; Hong Wei; Antti Pertovaara. "Descending antinociception induced by secondary somatosensory cortex stimulation in experimental neuropathy: role of the medullospinal serotonergic pathway". Journal of Neurophysiology 117 3 (2017): 1200-1214. https://doi.org/10.1152/jn.00836.2016.
    10.1152/jn.00836.2016
  13. Pereira, Ana Carla David; Sagalajev, Boriss; Wei, Hong; Almeida, Armando; Pertovaara, Antti; Pinto-Ribeiro, Filipa. "The medullary dorsal reticular nucleus as a relay for descending pronociception induced by the mGluR5 in the rat infralimbic cortex". (2017): http://hdl.handle.net/1822/49118.
    10.1016/j.neuroscience.2017.02.046
  14. Amorim, Diana Alexandra Silva; Puga, Sónia Andreia Silva; Bragança, Rui Pedro Rebelo; Braga, António José Falcão Peres; Pertovaara, Antti; Almeida, Armando; Pinto-Ribeiro, Filipa. "Minocycline reduces mechanical allodynia and depressive-like behaviour in type-1 diabetes mellitus in the rat". (2017): http://hdl.handle.net/1822/49098.
    10.1016/j.bbr.2017.03.003
  15. Pertovaara A. "Multi-target treatment of bone cancer pain using synergistic combinations of pharmacological compounds in experimental animals.". Scandinavian journal of pain (2016): http://europepmc.org/abstract/med/28850433.
    10.1016/j.sjpain.2016.11.001
  16. Hong Wei; Hai-Yun Wu; Zuyue Chen; Ai-Niu Ma; Xiao-Fang Mao; Teng-Fei Li; Xin-Yan Li; Yong-Xiang Wang; Antti Pertovaara. "Mechanical antihypersensitivity effect induced by repeated spinal administrations of a TRPA1 antagonist or a gap junction decoupler in peripheral neuropathy". Pharmacology Biochemistry and Behavior 150-151 (2016): 57-67. https://doi.org/10.1016%2Fj.pbb.2016.09.007.
    10.1016/j.pbb.2016.09.007
  17. Pauliina Lindholm; Salla Lamusuo; Tero Taiminen; Arja Virtanen; Antti Yrjö Pertovaara; Heli Forssell; Nora Hagelberg; Satu Jaaskelainen. "The analgesic effect of therapeutic rTMS is not mediated or predicted by comorbid psychiatric or sleep disorders". Medicine (Baltimore) 95 44 (2016): https://tuhat.helsinki.fi/portal/en/publications/the-analgesic-effect-of-therapeutic-rtms-is-not-mediated-or-predicted-by-comorbid-psychiatric-or-sleep-disorders(758c516d-9838-422d-9ce3-281000a02edc).html.
    10.1097/MD.0000000000005231
  18. Viisanen H; Chapman H; Wei H; Lasierra Losada M; Koivisto A; Akerman KE; Pertovaara A. "Pronociceptive effects induced by cutaneous application of a transient receptor potential ankyrin 1 (TRPA1) channel agonist methylglyoxal in diabetic animals: comparison with tunicamycin-induced endoplastic reticulum stress.". Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (2016): http://europepmc.org/abstract/med/27779479.
  19. Zhilin Li; Hong Wei; Sami Lauri Juhani Piirainen; Zuyue Chen; Eija Anneli Kalso; Antti Yrjö Pertovaara; Li Tian. "Spinal versus brain microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain". Brain, Behavior, and Immunity 58 November (2016): 107-117. https://tuhat.helsinki.fi/portal/en/publications/spinal-versus-brain-microglial-and-macrophage-activation-traits-determine-the-differential-neuroinflammatory-responses-and-analgesic-effect-of-minocycline-in-chronic-neuropathic-pain(8260acc7-c450-43e8-be32.
    10.1016/j.bbi.2016.05.021
  20. Hong Wei; Hai-Yun Wu; Hui Fan; Teng-Fei Li; Ai-Niu Ma; Xin-Yan Li; Yong-Xiang Wang; Antti Pertovaara. "Potential role of spinal TRPA1 channels in antinociceptive tolerance to spinally administered morphine". Pharmacological Reports 68 2 (2016): 472-475. https://doi.org/10.1016%2Fj.pharep.2015.11.008.
    10.1016/j.pharep.2015.11.008
  21. Hong Wei; Hanna Viisanen-Kuopila; Hao-Jun You; Antti Yrjö Pertovaara. "Spinal histamine in attenuation of mechanical hypersensitivity in the spinal nerve ligation-induced model of experimental neuropathy". European Journal of Pharmacology 772 (2016): 1-10. https://tuhat.helsinki.fi/portal/en/publications/spinal-histamine-in-attenuation-of-mechanical-hypersensitivity-in-the-spinal-nerve-ligationinduced-model-of-experimental-neuropathy(ef7bf1ef-58e5-4f6a-a1ab-a209f69e9e35).html.
    10.1016/j.ejphar.2015.12.039
  22. A. David-Pereira; S. Puga; S. Goncalves; D. Amorim; C. Silva; Antti Yrjö Pertovaara; A. Almeida; F. Pinto-Ribeiro. "METABOTROPIC GLUTAMATE 5 RECEPTOR IN THE INFRALIMBIC CORTEX CONTRIBUTES TO DESCENDING PAIN FACILITATION IN HEALTHY AND ARTHRITIC ANIMALS". Neuroscience 312 (2016): 108-119. https://tuhat.helsinki.fi/portal/en/publications/metabotropic-glutamate-5-receptor-in-the-infralimbic-cortex-contributes-to-descending-pain-facilitation-in-healthy-and-arthritic-animals(68cbf331-3330-4633-b504-71a6c0e5af4e).html.
    10.1016/j.neuroscience.2015.10.060
  23. Antti Yrjö Pertovaara. "Kuinka kipuselektiivinen on aivojen pihtipoimun dorsaalisen etuosan aktivaatio?". Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 1 (2016): 86-87. https://tuhat.helsinki.fi/portal/en/publications/kuinka-kipuselektiivinen-on-aivojen-pihtipoimun-dorsaalisen-etuosan-aktivaatio(8cf19d4c-ed64-4093-a3bc-ccc3fc1879db).html.
  24. Antti Yrjö Pertovaara; Harald Breivik. "Pain treatment with intrathecal corticosteroids: Much ado about nothing? But epidural corticosteroids for radicular pain is still an option". Scandinavian journal of pain 10 (2016): 82-84. https://tuhat.helsinki.fi/portal/en/publications/pain-treatment-with-intrathecal-corticosteroids-much-ado-about-nothing-but-epidural-corticosteroids-for-radicular-pain-is-still-an-option(afdd0ee2-d4ee-40d7-857e-791341f0b6da).html.
    10.1016/j.sjpain.2015.10.007
  25. Antti Yrjö Pertovaara. "Mechanisms of cognitive impairment in chronic pain patients can now be studied preclinically by inducing cognitive deficits with an experimental animal model of chronic neuropathic pain". Scandinavian journal of pain 10 (2016): 106-107. https://tuhat.helsinki.fi/portal/en/publications/mechanisms-of-cognitive-impairment-in-chronic-pain-patients-can-now-be-studied-preclinically-by-inducing-cognitive-deficits-with-an-experimental-animal-model-of-chronic-neuropathic-pain(7592bf46-159f-4d59-b.
    10.1016/j.sjpain.2015.11.006
  26. Antti, Pertovaara. "Regulation of neuropathic pain behavior by amygdaloid TRPC4/C5 channels". Neuroscience Letters (2015):
    10.1016/j.neulet.2015.09.033
  27. Pauliina Lindholm; Salla Lamusuo; Tero Taiminen; Ullamari Pesonen; Ari Lahti; Arja Virtanen; Heli Forssell; et al. "Right secondary somatosensory cortex-a promising novel target for the treatment of drug-resistant neuropathic orofacial pain with repetitive transcranial magnetic stimulation". Pain 156 7 (2015): 1276-1283. https://tuhat.helsinki.fi/portal/en/publications/right-secondary-somatosensory-cortexa-promising-novel-target-for-the-treatment-of-drugresistant-neuropathic-orofacial-pain-with-repetitive-transcranial-magnetic-stimulation(cfbfea83-d7d1-4694-87f2-c35d599d2.
    10.1097/j.pain.0000000000000175
  28. Antti, Pertovaara. "Bidirectional amygdaloid control of neuropathic hypersensitivity mediated by descending serotonergic pathways acting on spinal 5-HT3 and 5-HT1A receptors". Behavioural Brain Research (2015):
    10.1016/j.bbr.2014.12.052
  29. Jing Lei; Antti Yrjö Pertovaara; Hao-Jun You. "Effects of simulated weightlessness on intramuscular hypertonic saline induced muscle nociception and spinal Fos expression in rats". Brain Research 1594 (2015): 204-214. https://tuhat.helsinki.fi/portal/en/publications/effects-of-simulated-weightlessness-on-intramuscular-hypertonic-saline-induced-muscle-nociception-and-spinal-fos-expression-in-rats(0643bc57-d26d-4b10-9663-5c918cba0559).html.
    10.1016/j.brainres.2014.11.022
  30. Juha Gogulski; Robert Boldt; Petri Savolainen; Jessica Guzman-Lopez; Synnöve Carlson; Antti Yrjö Pertovaara. "A Segregated Neural Pathway for Prefrontal Top-Down Control of Tactile Discrimination". Cerebral Cortex 25 1 (2015): 161-166. https://tuhat.helsinki.fi/portal/en/publications/a-segregated-neural-pathway-for-prefrontal-topdown-control-of-tactile-discrimination(43c4ebf1-a78e-465d-afbb-ad1c0dde5b84).html.
    10.1093/cercor/bht211
  31. Amorim, Diana; Viisanen, Hanna; Wei, Hong; Almeida, Armando; Pertovaara, Antti; Pinto-Ribeiro, Filipa. "Galanin-mediated behavioural hyperalgesia from the dorsomedial nucleus of the hypothalamus involves two independent descending pronociceptive pathways". (2015): http://hdl.handle.net/1822/40841.
    10.1371/journal.pone.0142919
  32. Antti Yrjö Pertovaara; Ari Koivisto. "TRPA1-ionikanava neuropaattisen kivun hoitokohteena". Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 1 (2015): 28-32. https://tuhat.helsinki.fi/portal/en/publications/trpa1ionikanava-neuropaattisen-kivun-hoitokohteena(ec663cd4-1fd4-4c6f-b88b-1b44074eec32).html.
  33. Antti Yrjö Pertovaara. "Systeeminen lidokaiini vaimentaa kipua voimistamalla kipusignaalin inhibitiota selkäytimessä". Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 2 (2015): 85-85. https://tuhat.helsinki.fi/portal/en/publications/systeeminen-lidokaiini-vaimentaa-kipua-voimistamalla-kipusignaalin-inhibitiota-selkaytimessa(ebfbc5e9-1edf-41b6-a695-28caddd97203).html.
  34. Antti Yrjö Pertovaara. "Selektiivinen keratinosyyttiärsyke aiheuttaa kipusolujen aktivaatiota". Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 2 (2015): 84-85. https://tuhat.helsinki.fi/portal/en/publications/selektiivinen-keratinosyyttiarsyke-aiheuttaa-kipusolujen-aktivaatiota(47104601-34c5-43e8-937f-a8e1f5b6b633).html.
  35. Antti, Pertovaara. "Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity". Pharmacological Research (2014):
    10.1016/j.phrs.2014.09.007
  36. Antti Pertovaara. "Sinomenine against neuropathic pain hypersensitivity". Scandinavian Journal of Pain 5 4 (2014): 248-248. https://doi.org/10.1016/j.sjpain.2014.08.002.
    10.1016/j.sjpain.2014.08.002
  37. Satu K. Jaaskelainen; Pauliina Lindholm; Tanja Valmunen; Ullamari Pesonen; Tero Taiminen; Arja Virtanen; Salla Lamusuo; et al. "Variation in the dopamine D2 receptor gene plays a key role in human pain and its modulation by transcranial magnetic stimulation". Pain 155 10 (2014): 2180-2187. https://tuhat.helsinki.fi/portal/en/publications/variation-in-the-dopamine-d2-receptor-gene-plays-a-key-role-in-human-pain-and-its-modulation-by-transcranial-magnetic-stimulation(dde06b3c-85c0-465d-b3e2-b6e602f04f50).html.
    10.1016/j.pain.2014.08.029
  38. Antti, Pertovaara. "Descending effect on spinal nociception by amygdaloid glutamate varies with the submodality of noxious test stimulation". Neuroscience Letters (2014):
    10.1016/j.neulet.2014.04.010
  39. Faculdade de Psicologia e de Ciências da Educação; Amorim, Diana; Pereira, Ana David; Marques, Patrícia; Puga, Sónia Andreia Silva; Rebelo, Patrícia; Costa, Patrício Soares; et al. "A role of supraspinal galanin in behavioural hyperalgesia in the rat". (2014): https://repositorio-aberto.up.pt/handle/10216/82392.
    10.1371/journal.pone.0113077
  40. Amorim, Diana; Pereira, Ana David; Pertovaara, Antti; Almeida, Armando; Ribeiro, Filipa Pinto. "Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis". (2014): http://hdl.handle.net/1822/32982.
    10.1016/j.bbr.2014.02.003
  41. Koivisto, A.; Chapman, H.; Jalava, N.; Korjamo, T.; Saarnilehto, M.; Lindstedt, K.; Pertovaara, A.. "TRPA1: A transducer and amplifier of pain and inflammation". Basic and Clinical Pharmacology and Toxicology 114 1 (2014): 50-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890798418&partnerID=MN8TOARS.
    10.1111/bcpt.12138
  42. Song, Z.; Viisanen, H.; Meyerson, B.A.; Pertovaara, A.; Linderoth, B.. "Efficacy of kilohertz-frequency and conventional spinal cord stimulation in rat models of different pain conditions". Neuromodulation (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84894483411&partnerID=MN8TOARS.
    10.1111/ner.12161
  43. Boldt, R.; Gogulski, J.; Gúzman-Lopéz, J.; Carlson, S.; Pertovaara, A.. "Two-point tactile discrimination ability is influenced by temporal features of stimulation". Experimental Brain Research (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896552751&partnerID=MN8TOARS.
    10.1007/s00221-014-3908-y
  44. Wei H; Saarnilehto M; Falck L; Viisanen H; Lasierra M; Koivisto A; Pertovaara A; et al. "Spinal transient receptor potential ankyrin 1 channel induces mechanical hypersensitivity, increases cutaneous blood flow, and mediates the pronociceptive action of dynorphin A.". Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 64 3 (2013): 331-340. http://europepmc.org/abstract/med/23959730.
  45. H. Wei; M. Saarnilehto; L. Falck; H. Viisanen; M. Lasierra; A. Koivisto; Antti Yrjö Pertovaara. "SPINAL TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1 CHANNEL INDUCES MECHANICAL HYPERSENSITIVITY, INCREASES CUTANEOUS BLOOD FLOW, AND MEDIATES THE PRONOCICEPTIVE ACTION OF DYNORPHIN A". Journal of Physiology and Pharmacology 64 3 (2013): 331-340. https://tuhat.helsinki.fi/portal/en/publications/spinal-transient-receptor-potential-ankyrin-1-channel-induces-mechanical-hypersensitivity-increases-cutaneous-blood-flow-and-mediates-the-pronociceptive-action-of-dynorphin-a(98c5b169-2973-43b9-88e5-182f98c.
  46. Faculdade de Psicologia e de Ciências da Educação; Ribeiro, Filipa Pinto; Amorim, Diana; Pereira, Ana Carla David; Monteiro, Ana Maria; Costa, Patrício Soares; Pertovaara, Antti; Almeida, Armando. "Pronociception from the dorsomedial nucleus of the hypothalamus is mediated by the rostral ventromedial medulla in healthy controls but is absent in arthritic animals". (2013): https://repositorio-aberto.up.pt/handle/10216/108192.
    10.1016/j.brainresbull.2013.10.001
  47. Wei, Hong; Viisanen, Hanna; Amorim, Diana; Koivisto, Ari; Pertovaara, Antti. "Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy". (2013): http://hdl.handle.net/1822/32930.
    10.1016/j.pbb.2012.12.014
  48. Koivisto, A.; Pertovaara, A.. "Transient receptor potential ankyrin 1 (TRPA1) ion channel in the pathophysiology of peripheral diabetic neuropathy". Scandinavian Journal of Pain 4 3 (2013): 129-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880043556&partnerID=MN8TOARS.
    10.1016/j.sjpain.2012.11.001
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  177. Mansikka, H.; Pertovaara, A.; Mansikka H; Pertovaara A. "Influence of selective a2-adrenergic agents on mustard oil-induced central hyperalgesia in rats". European Journal of Pharmacology 281 1 (1995): 43-48. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028983153&partnerID=MN8TOARS.
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  178. Linnankoski, I.; Grönroos, M.; Carlson, S.; Pertovaara, A.. "Effect of cocaine on sexual behaviour in male stumptail macaques (Macaca arctoides)". Pharmacology Biochemistry and Behavior 52 1 (1995): 211-216. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029127563&partnerID=MN8TOARS.
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  179. Kauppila, T.; Grönroos, M.; Pertovaara, A.. "An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist". Pharmacology Biochemistry and Behavior 52 3 (1995): 641-644. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029115798&partnerID=MN8TOARS.
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  180. Taira, T.; Tanila, H.; Jyväsjärvi, E.; Pertovaara, A.; Kauppila, T.; Taira T; Tanila H; et al. "Activation of a2-adrenergic receptors decreases nerve trauma-induced afferent barrage but not autotomy". Brain Research Bulletin 36 6 (1995): 563-567. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028985347&partnerID=MN8TOARS.
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  181. M M HAMALAINEN; E JYVASJARVI; Antti Yrjö Pertovaara. "CAN THE ALPHA(2)-ADRENOCEPTOR AGONIST-MEDIATED SUPPRESSION OF NOCIFENSIVE REFLEX RESPONSES BE DUE TO ACTION ON MOTONEURONS OR PERIPHERAL NOCICEPTORS". Neuroscience Letters 196 (1995): 29-32. https://tuhat.helsinki.fi/portal/en/publications/can-the-alpha2adrenoceptor-agonistmediated-suppression-of-nocifensive-reflex-responses-be-due-to-action-on-motoneurons-or-peripheral-nociceptors(1ff22bbb-043a-405e-a279-b7b2ec1e2a97).html.
  182. Pertovaara A; Hämäläinen MM; Pertovaara, A.; Hamalainen, M.M.. "Spinal potentiation and supraspinal additivity in the antinociceptive interaction between systemically administered alpha 2-adrenoceptor agonist and cocaine in the rat.". Anesthesia and analgesia 79 2 (1994): 261-266. http://europepmc.org/abstract/med/7639361.
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  183. Helminen R; Mansikka H; Pertovaara A; Helminen, R.; Mansikka, H.; Pertovaara, A.. "Lowered or increased cutaneous sensitivity during movement depends on stimulus intensity.". Perceptual and motor skills 78 3 Pt 1 (1994): 721-722. http://europepmc.org/abstract/med/8084680.
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  184. Pertovaara A; Hämäläinen MM; Kauppila T; Mecke E; Carlson S; Pertovaara, A.; Hämäläinen, M.M.; et al. "Dissociation of the alpha 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats.". Pain 57 2 (1994): 207-215. http://europepmc.org/abstract/med/7916451.
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  185. Grönroos M; Pertovaara A; Gronroos, M.; Pertovaara, A.. "A selective suppression of human pain sensitivity by carbon dioxide: central mechanisms implicated.". European journal of applied physiology and occupational physiology 68 1 (1994): 74-79. http://europepmc.org/abstract/med/8162926.
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  186. Luuko, M.; Konttinen, Y.; Kemppinen, P.; Pertovaara, A.. "Influence of various experimental parameters on the incidence of thermal and mechanical hyperalgesia induced by a constriction mononeuropathy of the sciatic nerve in lightly anesthetized rats". Experimental Neurology 128 1 (1994): 143-154. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028111637&partnerID=MN8TOARS.
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  188. Gronroos, M.; Huttunen, J.; Pertovaara, A.. "Capsaicin-induced central facilitation of the somatosensory evoked potential in humans". Neuroscience Research Communications 14 2 (1994): 71-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028227010&partnerID=MN8TOARS.
  189. Grönroos, M.; Naukkarinen, H.; Pertovaara, A.. "Capsaicin-induced central facilitation of a sympathetic vasoconstrictor response to painful stimulation in humans". Neuroscience Letters 182 2 (1994): 163-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028037265&partnerID=MN8TOARS.
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  190. Kemppainen, P.; Leppanen, H.; Jyvasjarvi, E.; Pertovaara, A.. "Blood flow increase in the orofacial area of humans induced by painful stimulation". Brain Research Bulletin 33 6 (1994): 655-662. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028334964&partnerID=MN8TOARS.
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  191. Konttinen, Y.T.; Kemppinen, P.; Segerberg, M.; Hukkanen, M.; Rees, R.; Santavirta, S.; Sorsa, T.; Pertovaara, A.; Polak, J.M.. "Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain". Arthritis and Rheumatism 37 7 (1994): 965-982. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028240438&partnerID=MN8TOARS.
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  192. Hämäläinen MM; Pertovaara A; Hämäläinen, M.M.; Pertovaara, A.. "The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.". Neuropharmacology 32 12 (1993): 1411-1418. http://europepmc.org/abstract/med/8152531.
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  193. Grönroos M; Pertovaara A; Gronroos, M.; Pertovaara, A.. "Capsaicin-induced central facilitation of a nociceptive flexion reflex in humans.". Neuroscience letters 159 1-2 (1993): 215-218. http://europepmc.org/abstract/med/8264971.
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  194. Linnankoski I; Grönroos M; Pertovaara A; Linnankoski, I.; Grönroos, M.; Pertovaara, A.. "Eye contact as a trigger of male sexual arousal in stump-tailed macaques (Macaca arctoides).". Folia primatologica; international journal of primatology 60 3 (1993): 181-184. http://europepmc.org/abstract/med/8225125.
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  196. Pertovaara, A.; Bravo, R.; Herdegen, T.; Pertovaara A; Bravo R; Herdegen T. "Induction and suppression of immediate-early genes in the rat brain by a selective alpha-2-adrenoceptor agonist and antagonist following noxious peripheral stimulation". Neuroscience 54 1 (1993): 117-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027207191&partnerID=MN8TOARS.
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  197. Kemppainen, P.; Leppänen, H.; Waltimo, A.; Pertovaara, A.. "Effects of jaw clenching, jaw movement and static jaw position on facial skin sensitivity to non-painful electrical stimulation in man". Archives of Oral Biology 38 4 (1993): 303-308. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027586673&partnerID=MN8TOARS.
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  198. Luukko, M.; Pertovaara, A.. "Influence of an experimental peripheral mononeuropathy on the responses of medial bulboreticular neurons to noxious skin stimulation and the modulation of the responses by an a2-adrenoceptor agonist in the rat". Experimental Neurology 124 2 (1993): 390-394. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027753819&partnerID=MN8TOARS.
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  199. M M HAMALAINEN; Antti Yrjö Pertovaara. "THE ROSTROVENTROMEDIAL MEDULLA IS NOT INVOLVED IN ALPHA(2)-ADRENOCEPTOR-MEDIATED ANTINOCICEPTION IN THE RAT". Neuropharmacology 32 (1993): 1411-1418. https://tuhat.helsinki.fi/portal/en/publications/the-rostroventromedial-medulla-is-not-involved-in-alpha2adrenoceptormediated-antinociception-in-the-rat(fc681474-7d04-450f-bb7d-71975265c089).html.
  200. Kauppila T; Mecke E; Pertovaara A; Kauppila, T.; Mecke, E.; Pertovaara, A.. "Enhancement of morphine-induced analgesia and attenuation of morphine-induced side-effects by cocaine in rats.". Pharmacology & toxicology 71 3 I (1992): 173-178. http://europepmc.org/abstract/med/1438038.
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  201. Kauppila T; Jyväsjärvi E; Pertovaara A; Kauppila, T.; Jyvasjarvi, E.; Pertovaara, A.. "Effects of atipamezole, an alpha 2-adrenoceptor antagonist, on the anesthesia induced by barbiturates and medetomidine.". Anesthesia and analgesia 75 3 (1992): 416-420. http://europepmc.org/abstract/med/1354946.
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  202. Linnankoski I; Grönroos M; Carlson S; Pertovaara A; Linnankoski, I.; Grönroos, M.; Carlson, S.; Pertovaara, A.. "Increased sexual behavior in male Macaca arctoides monkeys produced by atipamezole, a selective alpha 2-adrenoceptor antagonist.". Pharmacology, biochemistry, and behavior 42 1 (1992): 197-200. http://europepmc.org/abstract/med/1356274.
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  203. Huopaniemi T; Jyväsjärvi E; Carlson S; Lindroos F; Pertovaara A. "Response characteristics of tooth pulp-driven postsynaptic neurons in the spinal trigeminal subnucleus oralis of the cat.". Acta physiologica Scandinavica (1992): http://europepmc.org/abstract/med/1575051.
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  207. T HUOPANIEMI; E JYVASJARVI; Synnöve Carlson; F LINDROOS; Antti Yrjö Pertovaara. "RESPONSE CHARACTERISTICS OF TOOTH PULP-DRIVEN POSTSYNAPTIC NEURONS IN THE SPINAL TRIGEMINAL SUBNUCLEUS ORALIS OF THE CAT". Acta physiologica Scandinavica 144 (1992): 177-183. https://tuhat.helsinki.fi/portal/en/publications/response-characteristics-of-tooth-pulpdriven-postsynaptic-neurons-in-the-spinal-trigeminal-subnucleus-oralis-of-the-cat(8f7e86ee-f957-4e65-a76d-50badef73473).html.
  208. Pertovaara A; Pertovaara, A.. "Antinociception in bulboreticular neurons of the rat produced by spinally administered medetomidine, an alpha 2-adrenoceptor agonist.". European journal of pharmacology 204 1 (1991): 9-14. http://europepmc.org/abstract/med/1687126.
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  210. Paalasmaa P; Kemppainen P; Pertovaara A; Paalasmaa, P.; Kemppainen, P.; Pertovaara, A.. "Modulation of skin sensitivity by dynamic and isometric exercise in man.". European journal of applied physiology and occupational physiology 62 4 (1991): 279-285. http://europepmc.org/abstract/med/2044539.
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  212. Mecke, E.; Kauppila, T.; Carlson, S.; Pertovaara, A.. "Differential effects of verapamil, a calcium channel antagonist, on morphine and cocaine-induced analgesia and locomotor behavior in rats". Neuroscience Research Communications 9 3 (1991): 137-141. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025938750&partnerID=MN8TOARS.
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  214. Kauppila, T.; Pertovaara, A.. "Effects of different sensory and behavioral manipulations on autotomy caused by a sciatic lesion in rats". Experimental Neurology 111 1 (1991): 128-130. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025976224&partnerID=MN8TOARS.
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  218. Belczynski CR; Pertovaara A; Morrow TJ; Casey KL; Belczynski Jr., C.R.; Pertovaara, A.; Morrow, T.J.; Casey, K.L.. "The effect of systemic cocaine on the responses to noxious stimuli and spontaneous activity of medial bulboreticular projection neurons.". Brain research 517 1-2 (1990): 344-346. http://europepmc.org/abstract/med/2253033.
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  235. Nurmikko, T.; Pertovaara, A.; Pontinen, P.J.; Nurmikko T; Pertovaara A; Pöntinen PJ. "Attenuation of tourniquet-induced pain in man by D-phenylalanine, a putative inhibitor of enkephalin degradation". Acupuncture and Electro-Therapeutics Research 12 3-4 (1987): 185-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023609260&partnerID=MN8TOARS.
    10.3727/036012987816358841
  236. Kekoni, J.; Pertovaara, A.; Hamalainen, H.; Kekoni J; Pertovaara A; Hämäläinen H. "Vibrotactile masking effects on airpuff-elicited sensations vary with skin region in the human hand". Somatosensory Research 5 2 (1987): 93-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023584603&partnerID=MN8TOARS.
    10.3109/07367228709144621
  237. Pertovaara, A.; Huopaniemi, T.; Carlson, S.; Jyvasjarvi, E.; Pertovaara A; Huopaniemi T; Carlson S; Jyväsjärvi E. "Response characteristics of tooth pulp-driven postsynaptic neurons in the spinal trigeminal subnucleus interpolaris of the cat: Comparison with primary afferent fiber, subnucleus caudalis, reflex, and sensory responses". Brain Research 422 2 (1987): 205-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023607358&partnerID=MN8TOARS.
    10.1016/0006-8993(87)90928-0
  238. Virtanen, A.S.J.; Huopaniemi, T.; Narhi, M.V.O.; Pertovaara, A.; Wallgren, K.; Virtanen AS; Huopaniemi T; et al. "The effect of temporal parameters on subjective sensations evoked by electrical tooth stimulation". Pain 30 3 (1987): 361-371. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023608183&partnerID=MN8TOARS.
    10.1016/0304-3959(87)90024-8
  239. Synnöve Carlson; Antti Yrjö Pertovaara; H TANILA. "LATE EFFECTS OF EARLY BINOCULAR VISUAL DEPRIVATION ON THE FUNCTION OF BRODMANNS AREA-7 OF MONKEYS (MACACA-ARCTOIDES)". Developmental Brain Research 33 (1987): 101-111. https://tuhat.helsinki.fi/portal/en/publications/late-effects-of-early-binocular-visual-deprivation-on-the-function-of-brodmanns-area7-of-monkeys-macacaarctoides(5f9097bb-31e5-45e4-bbcd-bfae07bf08d5).html.
  240. Pertovaara, A.; Kemppainen, P.; Huopaniemi, T.; Johansson, G.; Pertovaara A; Kemppainen P; Huopaniemi T; Johansson G. "Pain and stress: Correlation of stress hormone release to pain modulation in man". Annals of Clinical Research 19 2 (1987): 83-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023243336&partnerID=MN8TOARS.
  241. Kojo, I.; Pertovaara, A.. "The effects of stimulus area and adaptation temperature on warm and heat pain thresholds in man.". International Journal of Neuroscience 32 3-4 (1987): 875-880. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023283701&partnerID=MN8TOARS.
    10.3109/00207458709043342
  242. J KEKONI; Antti Yrjö Pertovaara; H HAMALAINEN. "VIBROTACTILE MASKING EFFECTS ON AIRPUFF-ELICITED SENSATIONS VARY WITH SKIN REGION IN THE HUMAN HAND". Somatosensory and Motor Research 5 (1987): 93-105. https://tuhat.helsinki.fi/portal/en/publications/vibrotactile-masking-effects-on-airpuffelicited-sensations-vary-with-skin-region-in-the-human-hand(82ab460d-82e2-4853-bf83-858bc1269f49).html.
  243. Pertovaara, A.; Huopaniemi, T.; Aukee, K.; Carlson, S.; Pertovaara A; Huopaniemi T; Aukee K; Carlson S. "Tooth pulp-evoked activity in the spinal trigeminal nucleus caudalis of cat: Comparison to primary afferent fiber, reflex, and sensory responses". Experimental Neurology 95 1 (1987): 155-166. http://www.scopus.com/inward/record.url?eid=2-s2.0-0023149292&partnerID=MN8TOARS.
    10.1016/0014-4886(87)90014-8
  244. Kojo I; Pertovaara A; Kojo, I.; Pertovaara, A.. "Effect of tourniquet-induced ischemia on cutaneous thermal thresholds.". Acta neurologica Scandinavica 74 5 (1986): 383-386. http://europepmc.org/abstract/med/3825496.
    10.1111/j.1600-0404.1986.tb03530.x
  245. Kemppainen P; Pertovaara A; Huopaniemi T; Johansson G; Kemppainen, P.; Pertovaara, A.; Huopaniemi, T.; Johansson, G.. "Elevation of dental pain threshold induced in man by physical exercise is not reversed by cyproheptadine-mediated suppression of growth hormone release.". Neuroscience letters 70 3 (1986): 388-392. http://europepmc.org/abstract/med/3774237.
    10.1016/0304-3940(86)90585-9
  246. Pertovaara A; Huopaniemi T; Aukee K; Pertovaara, A.; Huopaniemi, T.; Aukee, K.. "Tooth pulp-evoked jaw-opening reflex in the cat: evidence for central facilitation induced by noxious discharge in the intradental nerve fibers.". Experimental neurology 92 1 (1986): 207-219. http://europepmc.org/abstract/med/3956650.
    10.1016/0014-4886(86)90135-4
  247. Pertovaara A; Tukeva T; Huopaniemi T; Pertovaara, A.; Tukeva, T.; Huopaniemi, T.. "Response variability to repeated mechanical stimulation of the skin in the dorsal column system.". Acta neurobiologiae experimentalis 46 4 (1986): 179-186. http://europepmc.org/abstract/med/3788668.
  248. Pertovaara A; Huopaniemi T; Tukeva T; Pertovaara, A.; Huopaniemi, T.; Tukeva, T.. "Liminal and supraliminal response characteristics of mechanoreceptive neurons in the cuneate nucleus of cat.". Experimental brain research 62 3 (1986): 486-494. http://europepmc.org/abstract/med/3720880.
    10.1007/bf00236027
  249. Antti Yrjö Pertovaara; Pentti Kemppainen; T Huopaniemi; G Johansson. "Modification of experimental pain in man: correlation to some endocrinological parameters". Psychiatria Fennica. Monographs Supplement (1986): 91-95. https://tuhat.helsinki.fi/portal/en/publications/modification-of-experimental-pain-in-man-correlation-to-some-endocrinological-parameters(7e40716f-7834-4c2a-9a6e-f5551f996011).html.
  250. Pertovaara, A.; Linnankoski, I.; Pertovaara A; Linnankoski I. "Tactile detection threshold determined with single sinusoidal mechanical pulses in the monkey skin". Perceptual and Motor Skills 63 3 (1986): 1180-1182. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022878787&partnerID=MN8TOARS.
    10.2466/pms.1986.63.3.1180
  251. Pertovaara A; Huopaniemi T; Pertovaara, A.; Huopaniemi, T.. "Effect of tourniquet-induced ischemia on magnitude scaling of tactile stimuli applied to the human hand.". Perceptual and motor skills 61 2 (1985): 535-544. http://europepmc.org/abstract/med/4069919.
    10.2466/pms.1985.61.2.535
  252. Hari R; Pertovaara A; Kemppainen P; Salminen J; Hari, R.; Pertovaara, A.; Kemppainen, P.; Salminen, J.. "The effect of tourniquet-induced ischemia on somatically evoked cerebral magnetic fields in man.". Acta neurologica Scandinavica 72 4 (1985): 419-426. http://europepmc.org/abstract/med/4082907.
    10.1111/j.1600-0404.1985.tb00894.x
  253. Pertovaara A; Kojo I; Pertovaara, A.; Kojo, I.. "Influence of the rate of temperature change on thermal thresholds in man.". Experimental neurology 87 3 (1985): 439-445. http://europepmc.org/abstract/med/3972047.
    10.1016/0014-4886(85)90174-8
  254. Kemppainen, P.; Pertovaara, A.; Huopaniemi, T.; Johansson, G.; Karonen, S.-L.; Kemppainen P; Pertovaara A; et al. "Modification of dental pain and cutaneous thermal sensitivity by physical exercise in man". Brain Research 360 1-2 (1985): 33-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-0022378051&partnerID=MN8TOARS.
    10.1016/0006-8993(85)91217-x
  255. Pertovaara A; Reinikainen K; Hari R; Pertovaara, A.; Reinikainen, K.; Hari, R.. "The activation of unmyelinated or myelinated afferent fibers by brief infrared laser pulses varies with skin type.". Brain research 307 1-2 (1984): 341-343. http://europepmc.org/abstract/med/6467002.
    10.1016/0006-8993(84)90490-6
  256. Hämäläinen H; Pertovaara A; Hamalainen, H.; Pertovaara, A.. "Vibrotactile thresholds in mechanoreceptive afferents innervating the foot pad of the cat. The importance of stimulus frequency and duration.". Acta physiologica Scandinavica 120 3 (1984): 321-327. http://europepmc.org/abstract/med/6741569.
    10.1111/j.1748-1716.1984.tb07390.x
  257. Nurmikko T; Pertovaara A; Nurmikko, T.; Pertovaara, A.. "Painful hyperaesthesia following resection of the lateral cutaneous nerve of the thigh.". Journal of neurology, neurosurgery, and psychiatry 47 3 (1984): 320-321. http://europepmc.org/abstract/med/6707686.
    10.1136/jnnp.47.3.320-a
  258. Nurmikko T; Pertovaara A; Pöntinen PJ; Marnela KM; Oja SS; Nurmikko, T.; Pertovaara, A.; Pontinen, P.J.. "Effect of L-tryptophan supplementation on ischemic pain.". Acupuncture & electro-therapeutics research 9 1 (1984): 45-55. http://europepmc.org/abstract/med/6145310.
    10.3727/036012984816714820
  259. Pertovaara, A.; Nurmikko, T.; Pontinen, P.J.. "Two separate components of pain produced by the submaximal effort tourniquet test". Pain 20 1 (1984): 53-58. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021137287&partnerID=MN8TOARS.
    10.1016/0304-3959(84)90810-8
  260. Pertovaara, A.; Koivula, T.; Leppaluoto, J.. "The influence of infarct size and pituitary release of endorphins on acute cardiac pain". IRCS Medical Science 12 9 (1984): http://www.scopus.com/inward/record.url?eid=2-s2.0-0021140449&partnerID=MN8TOARS.
  261. Pertovaara, A.. "The effect of physical exercise on dental pain thresholds". IRCS Medical Science 12 1 (1984): http://www.scopus.com/inward/record.url?eid=2-s2.0-0021348568&partnerID=MN8TOARS.
  262. Pertovaara, A.; Huopaniemi, T.; Virtanen, A.; Johansson, G.. "The influence of exercise on dental pain thresholds and the release of stress hormones". Physiology and Behavior 33 6 (1984): 923-926. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021743511&partnerID=MN8TOARS.
    10.1016/0031-9384(84)90230-0
  263. Pertovaara, A.; Nurmikko, T.; Pontinen, P.J.. "TWO SEPARATE COMPONENTS OF PAIN PRODUCED BY THE SUBMAXIMAL EFFORT TOURNIQUET TEST.". Acupuncture and Electro-Therapeutics Research 8 2 (1983): http://www.scopus.com/inward/record.url?eid=2-s2.0-0020898034&partnerID=MN8TOARS.
  264. Hamalainen, H.; Pertovaara, A.; Hämäläinen H; Pertovaara A. "Liminal and supraliminal response characteristics of mechanoreceptors of the hairy and foot pad skin of cat determined with short tactile pulses". Quarterly Journal of Experimental Physiology 68 4 (1983): 619-627. http://www.scopus.com/inward/record.url?eid=2-s2.0-0021036526&partnerID=MN8TOARS.
    10.1113/expphysiol.1983.sp002752
  265. Nurmikko, T.; Pertovaara, A.; Pontinen, P.J.. "EFFECT OF L-TRYPTOPHAN SUPPLEMENTATION ON ISCHAEMIC PAIN.". Acupuncture and Electro-Therapeutics Research 8 2 (1983): http://www.scopus.com/inward/record.url?eid=2-s2.0-0020896831&partnerID=MN8TOARS.
  266. Pertovaara A; Hämäläinen H; Pertovaara, A.; Hämäläinen, H.. "Vibrotactile threshold elevation produced by high-frequency transcutaneous electrical nerve stimulation.". Archives of physical medicine and rehabilitation 63 12 (1982): 597-600. http://europepmc.org/abstract/med/6983336.
  267. Pertovaara, A.; Kemppainen, P.; Johansson, G.; Karonen, S.L.. "Ischemic pain nonsegmentally produces a predominant reduction of pain and thermal sensitivity in man: A selective role for endogenous opioids". Brain Research 251 1 (1982): 83-92. http://www.scopus.com/inward/record.url?eid=2-s2.0-0019945257&partnerID=MN8TOARS.
    10.1016/0006-8993(82)91276-8
  268. Pertovaara, A.; Kemppainen, P.; Johansson, G.; Karonen, S.L.. "Dental analgesia produced by non-painful, low-frequency stimulation is not influenced by stress or reversed by naloxone". Pain 13 4 (1982): 379-384. http://www.scopus.com/inward/record.url?eid=2-s2.0-0019943671&partnerID=MN8TOARS.
    10.1016/0304-3959(82)90006-9
  269. Pertovaara A; Hämäläinen H; Pertovaara, A.; Hamalainen, H.. "Vibrotactile thresholds in non-Pacinian mechanoreceptive afferents: the importance of temporal parameters.". Acta physiologica Scandinavica 113 4 (1981): 519-522. http://europepmc.org/abstract/med/7348035.
    10.1111/j.1748-1716.1981.tb06931.x
  270. Pertovaara A; Kemppainen P; Pertovaara, A.; Kemppainen, P.. "The influence of naloxone on dental pain threshold elevation produced by peripheral conditioning stimulation at high frequency.". Brain research 215 1-2 (1981): 426-429. http://europepmc.org/abstract/med/6973381.
    10.1016/0006-8993(81)90529-1
  271. Hämäläinen H; Pertovaara A; Soininen K; Järvilehto T; Hämäläinen, H.; Pertovaara, A.; Soininen, K.; Järvilehto, T.. "Is there low frequency vibrotactile temporal summation?". Scandinavian journal of psychology 22 3 (1981): 203-206. http://europepmc.org/abstract/med/7330616.
    10.1111/j.1467-9450.1981.tb00395.x
  272. Hyvärinen J; Pertovaara A. "[The sense of pain and its neurophysiology]". Duodecim; laaketieteellinen aikakauskirja (1981): http://europepmc.org/abstract/med/6119194.
  273. Hyvärinen, J.; Pertovaara, A.. "The sense of pain and its neurophysiology | Kipuaistin toiminta ja kivun neurofysiologia.". Duodecim 97 14 (1981): 1018-1030. http://www.scopus.com/inward/record.url?eid=2-s2.0-0019742843&partnerID=MN8TOARS.
  274. Antti Yrjö Pertovaara; H HAMALAINEN. "VIBROTACTILE THRESHOLDS DURING BACKGROUND VIBRATION OF LONG DURATION". Scandinavian Journal of Psychology 22 (1981): 41-45. https://tuhat.helsinki.fi/portal/en/publications/vibrotactile-thresholds-during-background-vibration-of-long-duration(2b98a248-e429-4e72-abfb-f51b1f843688).html.
  275. Pertovaara A; Pertovaara, A.. "Experimental pain and transcutaneous electrical nerve stimulation at high frequency.". Applied neurophysiology 43 6 (1980): 290-297. http://europepmc.org/abstract/med/7294774.
    10.1159/000102268
  276. Pertovaara, A.; Pertovaara A. "Modification of human pain threshold by specific tactile receptors". Acta Physiologica Scandinavica 107 4 (1979): 339-341. http://www.scopus.com/inward/record.url?eid=2-s2.0-0018571625&partnerID=MN8TOARS.
    10.1111/j.1748-1716.1979.tb06485.x
Capítulo de livro
  1. Ari Koivisto; Antti Yrjö Pertovaara. "Transient receptor potential ankyrin 1 channel antagonists for pain relief". editado por Arpad Szallasi, 145-162. Elsevier Scientific Publ. Co, 2015.
  2. Antti Yrjö Pertovaara. "Descending modulation and persistent pain". editado por Gerald Gebhart; Robert Schmidt. Springer-Verlag, 2013.
    10.1007/978-3-642-28753-4
  3. Nora Hagelberg; Antti Yrjö Pertovaara. "Opioidit". editado por Markku Koulu; Eero Mervaala, 359-378. Kustannusosakeyhtiö Medicina, Kuopio, 2013.
  4. Nora Hagelberg; Antti Yrjö Pertovaara. "Opioidit". editado por Markku Koulu; Eero Mervaala; Jouko Tuomisto, 359-378. Kustannusosakeyhtiö Medicina, Kuopio, 2012.
  5. Antti Yrjö Pertovaara. "Noradrenergic pathology and pain". 385-407. Cambridge University Press, 2007.
  6. Antti Yrjö Pertovaara. "Descending modulation and persistent pain". 564-566. Springer-Verlag, 2007.
  7. Nora Hagelberg; Antti Yrjö Pertovaara. "Opioidit". editado por Markku Koulu; Jouko Tuomisto, 343-362. Medicina, 2007.
  8. Antti Yrjö Pertovaara. "Kivun patofysiologia". editado por H Alaranta; T Pohjolainen; P Rissanen; H Vanharanta; M Attila; E Kuusela; M Raekallio; O Vainio, 53-61. Duodecim, 1997.
  9. H Mansikka; Antti Yrjö Pertovaara. "Neurogenic inflammation of the skin induces plastic changes in alpha 2-adrenergic pain modulation in rats". editado por V Torre; F Conti, 175-182. Plenum Press, 1996.
  10. Antti Yrjö Pertovaara. "Kivun säätely". editado por A Revonsuo; H Lang; O Aaltonen, 115-122. University of Turku, 1996.
  11. Antti Yrjö Pertovaara. "Kipuaisti ja sen toiminta". editado por J.-J. Himberg; M Iivanainen; P Karli, 71-76. Otava, 1994.
  12. Antti Yrjö Pertovaara; Pentti Kemppainen; O Vuolteenaho; J Leppäluoto. "The effect of tourniquet-induced ischemic pain on electrotactile thresholds, blood pressure, and beta-endorphin level in plasma". editado por B Bromm, 475-481. Elsevier Scientific Publ. Co, 1984.
  13. Antti Yrjö Pertovaara. "Kipuaistimuksen muuntelun neurofysiologiaa". 13-17. Helsingin lääkäriyhdistys, 1980.
  14. Antti Yrjö Pertovaara. "Kivun mekanismeista". 28-30. Kandidaattikustannus Oy/ Lääketieteen kandidaattiseura ry, 1979.
Livro
  1. Pertovaara, A.; Antti Yrjö Pertovaara. Adrenergic Receptors. Wiley. 2009.
    10.1002/9780470522226.ch11
  2. Pertovaara, Antti; Almeida, Armando. Endogenous pain modulation : descending inhibitory systems. Elsevier. 2006.
  3. Pertovaara, A.; Almeida, A.. Chapter 13 Descending inhibitory systems. 2006.
    10.1016/S0072-9752(06)80017-5
  4. Pertovaara, A.. Plasticity in descending pain modulatory systems. 2000.
    10.1016/S0079-6123(00)29017-1
Revisão de livro
  1. Antti Yrjö Pertovaara. "F1000Prime Recommendation". (2014): http://f1000.com/prime/718318760#eval793492435.
    10.3410/f.718318760.793492435
Tese / Dissertação
  1. Gonçalves, Leonor. "Plasticity of the pain control system induced by neuropathic pain: the amygdala-medulla system". Doutoramento, 2009. http://hdl.handle.net/1822/9477.
  2. Antti, Pertovaara. "Somatosensory thresholds and their modification by peripheral conditioning stimulaton". 1982. https://tuhat.helsinki.fi/portal/en/publications/somatosensory-thresholds-and-their-modification-by-peripheral-conditioning-stimulaton(7e0427a5-124a-4356-b59e-d6e169ab4181).html.

Propriedade Intelectual

Patente
  1. P Panula; Antti Yrjö Pertovaara; E Kalso; E Korpi. 2005. "Method for regulating autonomic functions and treating pain".
  2. I Linnankoski; Antti Yrjö Pertovaara; A Haapalinna; R Virtanen. 2002. "A method for the treatment of female sexual dysfunction and enhancement of normal sexual function in females with an alpha.sub.2-adrenoceptor antagonist or a pharmaceutically acceptable ester or salt thereof".
  3. Antti Yrjö Pertovaara; I Linnankoski; R Virtanen. 1996. "Administration of atipamezole to elicit a yohimbine-like alpha-adrenoceptor antagonistic noradrenergic transmission".

Outros

Outra produção
  1. Data from the manuscript [A role of supraspinal galanin in behavioural hyperalgesia in the rat]. In chronic pain disorders, galanin (GAL) is able to either facilitate or inhibit nociception in the spinal cord but the contribution of supraspinal galanin to pain signalling is mostly unknown. The dorsomedial nucleus of the hypothalamus (DMH) is rich in galanin receptors (GALR) and is involved in behavioural hyperalgesia. In this study, we evaluated the contribution of supraspinal GAL to behaviou. 2014. Amorim, Diana; David-Pereira, Ana; Marques, Patrícia; Puga, Sónia Andreia Silva; Rebelo, Patrícia; Costa, Patrício Soares; Pertovaara, Antti; Almeida, Armando; Pinto-Ribeiro, Filipa. http://hdl.handle.net/1822/30587.
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2016 - 2020/03/20 Plasticity in descending modulation of pain: Therapeutic effects of non-painful heating-needle stimulation and its potential mechanisms
Coorientador de Jing Lei
 Physiology (Doutoramento)
Helsingin yliopisto - Meilahden kampus, Finlândia
2014 - 2018 Prefrontal control of the tactile sense
Coorientador de Juha Gogulski
 Physiology (Doutoramento)
Helsingin yliopisto - Meilahden kampus, Finlândia
2013 - 2017 Neuropathic pain: Amygdaloid stress as culprit and cortical stimulation as treatment.
Orientador de Boriss Sagalajev
 Physiology
Helsingin yliopisto - Meilahden kampus, Finlândia
2010/01/01 - 2015/08/05 Central nucleus of the amygdala in descending control of pain-related behavior.
Orientador de Nora Bourbia
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
2008 - 2012 Descending modulation of pain by motor cortex stimulation in the rat. Efficacy and mechanisms in peripheral neuropathy.
Orientador de Hanna Viisanen
 Physiology (Doutoramento)
Helsingin yliopisto - Meilahden kampus, Finlândia
2005 - 2009 Brain dopamine and serotonin receptors and perception of pain. Positron emission tomography studies in healthy subjects.
Coorientador de Ilkka Martikainen
 Physiology (Doutoramento)
Turun Yliopisto, Finlândia
2005 - 2008 Plasticy of the Pain Control System Induced by Neuropathic Pain: the Amygdala-medulla System
Coorientador de Maria Leonor Barbosa Gonçalves
 Ciências da Saúde (Doutoramento)
Universidade do Minho, Portugal
1996 - 2000 Descending modulation of neuropathic pain in rats.
Orientador de Hong Wei
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1994 - 1998 The role of capsaicin-sensitive nerve fibers in secondary hyperalgesia and chronic itch in humans.
Orientador de Mari Grönroos
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1994 - 1997 The role of alpha-2-adrenoceptors, brain stem nuclei and peripheral afferent fibers in experimental pathophysiologic pain in rats.
Orientador de Heikki Mansikka
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1992 - 1996 Factors affecting recovery from peripheral nerve injury-induced symptoms in the rat.
Orientador de Timo Kauppila
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1992 - 1996 Supraspinal alpha-2-adrenergic receptors in antinociception in the rat.
Orientador de Minna M. Hämäläinen
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1990 - 1994 Characteristics and determinants of sexual behaviour of laboratory-housed stumptail macaques (Macaca arctoides).
Orientador de Ilkka Linnankoski
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1989 - 1993 Sensory, motor, and memory functions of the prefrontal cortex in the monkey, and the effects of alpha-2-adrenergic drugs on memory in rats.
Coorientador de Heikki Tanila
Helsingin yliopisto, Finlândia
1986 - 1990 The psychophysiology of thermal sensation and imagery: an experimental model for the placebo effect.
Orientador de Ilpo Kojo
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
1982 - 1985 Modification of human dental pain thresholds by conditioning stimulation.
Orientador de Pentti Kemppainen
 Physiology (Doutoramento)
Helsingin yliopisto, Finlândia
Distinções

Prémio

2003 Senior Fellowship
Suomen Akatemia, Finlândia
2001 Senior Fellowship
Sigrid Juséliuksen Säätiö, Finlândia
1991 Research Fellowship
Alexander von Humboldt-Stiftung, Alemanha
1990 Senior Fellowship
Suomen Akatemia, Finlândia
1986 Fogarty Fellowship
National Institutes of Health, Estados Unidos