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José Teixeira (JT) is a Researcher in the MitoPerOx ¿ Mitochondrial-Peroxisome Metabolic and Redox Crosstalk group at the Center for Neuroscience and Cell Biology (CNC), University of Coimbra (UC), Portugal. José Teixeira graduated in Biochemistry from the University of Trás-os-Montes and Alto Douro (Portugal) and obtained the MSc in Biochemistry and the PhD studies in Pharmaceutical Sciences from the University of Porto (Portugal). JT research interests is focused to understand the cellular and molecular mechanisms underlying mechanotransduction impact on the role of mitochondria and peroxisome in lipid and ROS metabolism during the progression of oxidative stress-related pathologies, notably Non-Alcoholic Fatty Liver Disease (NAFLD), and in the development and evaluation of the potential biological effects of mitochondria-targeted antioxidants based on naturally dietary scaffolds as a therapeutic solution. The results of his investigation (2010-2023) are patent 42 peer-reviewed publications (31 being original articles), counting over 1000 citations and an h-index of 19. JT is also a co-inventor in 2 patent applications (WO2018069904 and WO2018122789). Research projects as principal investigator (PI): “SkinSHIELD - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active ingredients (PTDC/BIO-MOL/28607/2017) (€232K) BraveHEART – Improving Nature by addressing bioactive dietary polyphenols to mitochondria for the protection of cardiac complications in Non-Alcoholic Fatty Liver Disease (EXPL/BIA-BQM/1361/2021) (€50K)
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Identificação

Identificação pessoal

Nome completo
José Carlos Santos Teixeira

Nomes de citação

  • Teixeira, José

Identificadores de autor

Ciência ID
1A15-A5EF-830E
ORCID iD
0000-0003-0834-5698
Researcher Id
N-9862-2014
Scopus Author Id
55881309000

Endereços de correio eletrónico

  • jose_8_teixeira@hotmail.com (Profissional)
  • jteixeira@cnc.uc.pt (Profissional)

Telefones

Telefone
  • 231249195 Ext.: 747 (Profissional)
Telemóvel
  • 919264318 (Pessoal)

Moradas

  • UC Biotech Building, Lot 8A, Biocant Park, 3060-197, Cantanhede , Coimbra , Portugal (Profissional)
  • Urbanização da Pedrulha, Lote 5 1º Esquerdo , 3025-248, Coimbra, Coimbra , Portugal (Pessoal)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Básica - Química Médica
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador proficiente (C1) Utilizador independente (B2)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A1)
Formação
Grau Classificação
2011/11/04 - 2016/05/30
Concluído
 Ciências Farmacêuticas (Doutoramento)
Especialização em Bioquímica
Universidade do Porto Faculdade de Farmácia, Portugal
"Targeting dietary antioxidants to mitochondria: regulating mitochondrial radical production and redox signaling to improve human health" (TESE/DISSERTAÇÃO)
2014/05/27 - 2014/05/28
Concluído
 Seahorse XFe96 uses and applications (Outros)
Especialização em Seahorse XFe96 Training Course
Agilent Technologies, Alemanha
2012/01/30 - 2012/02/10
Concluído
 Laboratory Animal Science Course (Outros)
Especialização em FELASA Cat B course in laboratory animal science
Universidade do Porto Faculdade de Medicina, Portugal
2009/10/02 - 2011/10/09
Concluído
 Bioquímica (Mestrado integrado)
Especialização em Química Medicinal
Universidade do Porto Faculdade de Ciências, Portugal
"DEVELOPMENT OF MITOCHONDRIA-TARGETED ANTIOXIDANTS BASED ON CINNAMIC SCAFFOLD AS A THERAPEUTIC SOLUTION FOR NEURODEGENERATIVE DISEASES" (TESE/DISSERTAÇÃO)
 17
2006/09/21 - 2009/07/07
Concluído
 Bioquímica (Licenciatura)
Especialização em Bioquímica
Universidade de Trás-os-Montes e Alto Douro, Portugal
"Avaliação dos efeitos da metabolização da N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)em mitocôndrias de fígado de rattus norvegicus" (TESE/DISSERTAÇÃO)
 15
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/05/02 - 2027/04/30 Investigador (Investigação) Universidade de Coimbra, Portugal
2019/06/01 - 2020/05/31 Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/07/01 - 2019/05/31 Investigador (Investigação) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2016/09/01 - 2017/06/30 Investigador (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/01/02 - 2015/12/31 Investigador (Investigação) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2015/01/05 - 2015/07/31 Investigador visitante (Investigação) Radboud Universiteit Radboud Institute for Molecular Life Sciences, Países Baixos
Radboud Universiteit Radboud Institute for Molecular Life Sciences, Países Baixos
2013/01/03 - 2014/12/31 Investigador visitante (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2011/03/01 - 2011/07/31 Investigador visitante (Investigação) Medical Research Council (MRC) , Reino Unido
Medical Research Council (MRC) , Reino Unido
2010/09/01 - 2011/02/05 Estagiário de Investigação (Investigação) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2009/02/01 - 2009/06/30 Estagiário de Investigação (Investigação) Universidade de Trás-os-Montes e Alto Douro Centro de Química Vila Real, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2007/10/01 - 2008/07/31 Estagiário de Investigação (Investigação) Universidade de Trás-os-Montes e Alto Douro, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2016/04/01 - 2016/08/31 Delegado de Informação Médica Morada Angelini Farmacêutica Lda, Portugal
Morada Angelini Farmacêutica Lda, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/06/01 - 2021/04/30 Director Técnico Mitotag, Lda, Portugal
Projetos

Projeto

Designação Financiadores
2021/05/03 - 2027/05/02 MitoMED - Targeting Mitochondria with a New Generation of Multi-Purpose Bioactive Molecules Inspired in Natural Scaffolds
2020.01560.CEECIND/CP1609/CT0011
10.54499/2020.01560.CEECIND/CP1609/CT0011
Investigador responsável
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2022/01/06 - 2023/12/31 Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2022/01/02 - 2023/12/31 BraveHEART: Melhorar a Natureza Através do Direcionamento de Moléculas Bioactivas Polifenólicas da Dieta para as Mitocôndrias para Minimizar as Complicações Cardíacas Associadas à Doença de Fígado Gordo Não Alcoólico
EXPL/BIA-BQM/1361/2021
10.54499/EXPL/BIA-BQM/1361/2021
Investigador responsável
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2021/01/01 - 2023/12/31 Organelle-targeted Radiocomplexes for Auger Therapy of Cancer
PTDC/MED-QUI/1554/2020
Investigador
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Centro de Ciências e Tecnologias Nucleares, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/09/02 - 2023/12/30 CôaMedPlants: Preservation of natural and cultural heritage and scientific validation of practices with medicinal plants from Côa Valley
COA/BRB/0019/2019
Investigador
Universidade de Coimbra, Portugal
Em curso
2022/06/01 - 2023/06/30 MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
CENTRO-01-0145-FEDER-181226
Investigador
Universidade de Coimbra, Portugal
 Comissão de Coordenação e Desenvolvimento Regional do Centro
Em curso
2018/07/26 - 2021/06/26 SkinSHIELD: Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active ingredients
POCI-01-0145-FEDER-028607 (PTDC/BIO-MOL/28607/2017)
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/05 - 2021/04 MitoScreening: Development and validation of innovative screening methods for mitochondrial health modulators.
POCI-01-0145-FEDER-029297
 N/A
2018/03/05 - 2020/04/30 MITO4ALS : Development of new mitochondria-targeted antioxidants to ameliorate the phenotype of the familial SOD1 amyotrophic lateral sclerosis
PTDC/MED-FAR/29391/2017
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 Centro de Investigação em Química da Universidade do Porto (Chemistry Research Center of the University of Porto)
UID/QUI/00081/2019
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro de Investigação em Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UID/QUI/50006/2019
LA/P/0008/2020
10.54499/LA/P/0008/2020
Universidade do Porto Faculdade de Ciências, Portugal

Universidade Nova de Lisboa, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Évora, Portugal

Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal

Universidade de Lisboa Instituto Dom Luiz, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/12/31 CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/09/01 - 2019/08/31 MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria Pathophysiology
PTDC/DTP-FTO/2433/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/06 - 2011/07/30 Fine-tuning the hydrophobicity of natural antioxidants: development of innovative mitochondria-targeted antioxidants based on benzoic acid scaffold
PP_IJUP2011 209
Outra
Universidade do Porto Faculdade de Ciências, Portugal
Produções

Publicações

Artigo em revista
  1. Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al. "Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism". Biochemical Pharmacology 219 (2024): 115953. http://dx.doi.org/10.1016/j.bcp.2023.115953.
    Publicado • 10.1016/j.bcp.2023.115953
  2. Diniz, Mariana S.; Magalhães, Carina C.; Tocantins, Carolina; Grilo, Luís F.; Teixeira, José; Pereira, Susana P.. "Nurturing through Nutrition: Exploring the Role of Antioxidants in Maternal Diet during Pregnancy to Mitigate Developmental Programming of Chronic Diseases". Nutrients 15 21 (2023): 4623. http://dx.doi.org/10.3390/nu15214623.
    Publicado • 10.3390/nu15214623
  3. Ricardo Amorim; Carina C. Magalhães; Fernanda Borges; Paulo J. Oliveira; José Teixeira. "From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria". Biology (2023): https://doi.org/10.3390/biology12040595.
    10.3390/biology12040595
  4. Inês Ramos Rego; Daniela Silvério; Maria Isabel Eufrásio; Sandra Sofia Pinhanços; Bruna Lopes da Costa; José Teixeira; Hugo Fernandes; et al. "TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status". Antioxidants (2023): https://doi.org/10.3390/antiox12020381.
    10.3390/antiox12020381
  5. Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Barreiro, Sandra; Cagide, Fernando; Sequeira, Lisa; Teixeira, José; et al. "Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks". Journal of Medicinal Chemistry 66 3 (2023): 1835-1851. http://dx.doi.org/10.1021/acs.jmedchem.2c01630.
    10.1021/acs.jmedchem.2c01630
  6. Afonso, Marta B.; Islam, Tawhidul; Magusto, Julie; Amorim, Ricardo; Lenoir, Véronique; Simões, Rui F.; Teixeira, José; et al. "RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease". Hepatology 77 4 (2022): 1319-1334. http://dx.doi.org/10.1002/hep.32756.
    10.1002/hep.32756
  7. Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira. "Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease". European Journal of Clinical Investigation (2022): https://doi.org/10.1111/eci.13820.
    10.1111/eci.13820
  8. Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al. "Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems". Redox Biology 55 (2022): 102400. http://dx.doi.org/10.1016/j.redox.2022.102400.
    10.1016/j.redox.2022.102400
  9. Reis, Joana; Fernandes, Carlos; Salem, Hoda; Maia, Marta; Tomé, Cláudia; Benfeito, Sofia; Teixeira, José; et al. "Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties". European Journal of Medicinal Chemistry 239 (2022): 114507. http://dx.doi.org/10.1016/j.ejmech.2022.114507.
    10.1016/j.ejmech.2022.114507
  10. Pessoa, João; Teixeira, José. "Cytoskeleton alterations in non-alcoholic fatty liver disease". Metabolism 128 (2022): 155115. http://dx.doi.org/10.1016/j.metabol.2021.155115.
    10.1016/j.metabol.2021.155115
  11. João Campos Santos; Carla Cruz Marques; Maria Conceição Baptista; Jorge Pimenta; José Carlos Santos Teixeira; Liliana Montezinho; Fernando Cagide; et al. "Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production". Animals (2022): https://www.mdpi.com/2076-2615/12/7/804.
    10.3390/ani12070804
  12. Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al. "Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage". Free Radical Biology and Medicine 179 (2022): 119-132. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304.
    10.1016/j.freeradbiomed.2021.12.304
  13. Fernandes, Carlos; Videira, Afonso J. C.; Veloso, Caroline D.; Benfeito, Sofia; Soares, Pedro; Martins, João D.; Gonçalves, Beatriz; et al. "Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis". Biomolecules 11 11 (2021): 1605. http://dx.doi.org/10.3390/biom11111605.
    10.3390/biom11111605
  14. Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al. "A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients". Redox Biology 45 (2021): 102037. http://dx.doi.org/10.1016/j.redox.2021.102037.
    10.1016/j.redox.2021.102037
  15. Simões, Inês C. M.; Amorim, Ricardo; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana; Pereira, Susana P.; Simões, Rui F.; et al. "The Alterations of Mitochondrial Function during NAFLD Progression—An Independent Effect of Mitochondrial ROS Production". International Journal of Molecular Sciences 22 13 (2021): 6848. http://dx.doi.org/10.3390/ijms22136848.
    10.3390/ijms22136848
  16. Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; et al. "Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells". Nutrients 13 5 (2021): 1723. http://dx.doi.org/10.3390/nu13051723.
    10.3390/nu13051723
  17. Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al. "Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts". Free Radical Biology and Medicine 163 (2021): 314-324. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023.
    10.1016/j.freeradbiomed.2020.12.023
  18. Belew, Getachew Debas; Silva, Joao; Rito, Joao; Tavares, Ludgero; Viegas, Ivan; Teixeira, Jose; Oliveira, Paulo J.; Macedo, Maria Paula; Jones, John G.. "Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis". Journal of Lipid Research 60 12 (2019): 2050-2056. http://dx.doi.org/10.1194/jlr.ra119000354.
    Publicado • 10.1194/jlr.ra119000354
  19. Oliveira, Catarina; Bagetta, Donatella; Cagide, Fernando; Teixeira, José; Amorim, Ricardo; Silva, Tiago; Garrido, Jorge; et al. "Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents". European Journal of Medicinal Chemistry 174 (2019): 116-129. http://dx.doi.org/10.1016/j.ejmech.2019.04.026.
    Publicado • 10.1016/j.ejmech.2019.04.026
  20. Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al. "Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction". European Journal of Medicinal Chemistry 167 (2019): 525-545. http://dx.doi.org/10.1016/j.ejmech.2019.01.055.
    Publicado • 10.1016/j.ejmech.2019.01.055
  21. Reis, Joana; Cagide, Fernando; Valencia, Martín Estrada; Teixeira, José; Bagetta, Donatella; Pérez, Concepción; Uriarte, Eugenio; et al. "Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors". European Journal of Medicinal Chemistry 158 (2018): 781-800. http://dx.doi.org/10.1016/j.ejmech.2018.07.056.
    Publicado • 10.1016/j.ejmech.2018.07.056
  22. Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges. "Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy". Bioconjugate Chemistry (2018): https://doi.org/10.1021/acs.bioconjchem.8b00383.
    Publicado • 10.1021/acs.bioconjchem.8b00383
  23. Jarak, Ivana; Barosa, Cristina; Martins, Fatima O.; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, Joao; et al. "Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrate". Magnetic Resonance in Medicine 81 1 (2018): 639-644. http://dx.doi.org/10.1002/mrm.27378.
    Publicado • 10.1002/mrm.27378
  24. Ribeiro, José A.; Benfeito, Sofia; Cagide, Fernando; Teixeira, José; Oliveira, Paulo J.; Borges, Fernanda; Silva, António F.; Pereira, Carlos M.. "Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity". Analytical Chemistry 90 13 (2018): 7989-7996. http://dx.doi.org/10.1021/acs.analchem.8b00787.
    Publicado • 10.1021/acs.analchem.8b00787
  25. Oliveira, Catarina; Cagide, Fernando; Teixeira, José; Amorim, Ricardo; Sequeira, Lisa; Mesiti, Francesco; Silva, Tiago; et al. "Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors". Frontiers in Chemistry 6 (2018): http://dx.doi.org/10.3389/fchem.2018.00126.
    Publicado • 10.3389/fchem.2018.00126
  26. Teixeira, José; Deus, Cláudia M.; Borges, Fernanda; Oliveira, Paulo J.. "Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants". The International Journal of Biochemistry & Cell Biology 97 (2018): 98-103. http://dx.doi.org/10.1016/j.biocel.2018.02.007.
    Publicado • 10.1016/j.biocel.2018.02.007
  27. José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira. "Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid". Journal of Enzyme Inhibition and Medicinal Chemistry 33 1 (2018): 567-576. https://doi.org/10.1080/14756366.2018.1442831.
    Publicado • 10.1080/14756366.2018.1442831
  28. Teixeira, J.; Basit, F.; Swarts, H.G.; Forkink, M.; Oliveira, P.J.; Willems, P.H.G.M.; Koopman, W.J.H.. "Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells". Redox Biology 15 (2018): 394-404. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040366459&partnerID=MN8TOARS.
    Publicado • 10.1016/j.redox.2017.12.018
  29. Teixeira, J.; Amorim, R.; Santos, K.; Soares, P.; Datta, S.; Cortopassi, G.A.; Serafim, T.L.; et al. "Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative". Toxicology 393 (2018): 123-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034013034&partnerID=MN8TOARS.
    Publicado • 10.1016/j.tox.2017.11.014
  30. Teixeira, J.; Chavarria, D.; Borges, F.; Wojtczak, L.; Wieckowski, M. R.; Karkucinska-Wieckowska, A.; Oliveira, P. J.. "Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease". Curr Med Chem (2017): https://www.ncbi.nlm.nih.gov/pubmed/28554320.
    Publicado • 10.2174/0929867324666170529101810
  31. Teixeira, J.; Oliveira, C.; Amorim, R.; Cagide, F.; Garrido, J.; Ribeiro, J.A.; Pereira, C.M.; et al. "Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria". Scientific Reports 7 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85026475854&partnerID=MN8TOARS.
    Publicado • 10.1038/s41598-017-07272-y
  32. Teixeira, J.; Cagide, F.; Benfeito, S.; Soares, P.; Garrido, J.; Baldeiras, I.; Ribeiro, J.A.; et al. "Development of a mitochondriotropic antioxidant based on caffeic acid: Proof of concept on cellular and mitochondrial oxidative stress models". Journal of Medicinal Chemistry 60 16 (2017): 7084-7098. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028330575&partnerID=MN8TOARS.
    Publicado • 10.1021/acs.jmedchem.7b00741
  33. Forkink, M.; Basit, F.; Teixeira, J.; Swarts, H.G.; Koopman, W.J.H.; Willems, P.H.G.M.. "Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells". Redox Biology 6 (2015): 607-616. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945395305&partnerID=MN8TOARS.
    Publicado • 10.1016/j.redox.2015.09.003
  34. Silva, T.; Reis, J.; Teixeira, J.; Borges, F.. "Alzheimer's disease, enzyme targets and drug discovery struggles: From natural products to drug prototypes". Ageing Research Reviews 15 1 (2014): 116-145. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899683262&partnerID=MN8TOARS.
    Publicado • 10.1016/j.arr.2014.03.008
  35. Benfeito, S.; Oliveira, C.; Soares, P.; Fernandes, C.; Silva, T.; Teixeira, J.; Borges, F.. "Antioxidant therapy: Still in search of the 'magic bullet'". Mitochondrion 13 5 (2013): 427-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882877558&partnerID=MN8TOARS.
    Publicado • 10.1016/j.mito.2012.12.002
  36. Teixeira, J.; Gaspar, A.; Garrido, E.M.; Garrido, J.; Borges, F.. "Hydroxycinnamic acid antioxidants: An electrochemical overview". BioMed Research International 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84881540701&partnerID=MN8TOARS.
    Publicado • 10.1155/2013/251754
  37. Teixeira, J.; Silva, T.; Benfeito, S.; Gaspar, A.; Garrido, E.M.; Garrido, J.; Borges, F.. "Exploring nature profits: Development of novel and potent lipophilic antioxidants based on galloyl-cinnamic hybrids". European Journal of Medicinal Chemistry 62 (2013): 289-296. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873030904&partnerID=MN8TOARS.
    Publicado • 10.1016/j.ejmech.2012.12.049
  38. Teixeira, J.; Silva, T.; Andrade, P.B.; Borges, F.. "Alzheimer's disease and antioxidant therapy: How long how far?". Current Medicinal Chemistry 20 24 (2013): 2939-2952. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880283997&partnerID=MN8TOARS.
    Publicado • 10.2174/1871523011320240001
  39. Oliveira, Maria M.; Teixeira, Jose C.; Vasconcelos-Nobrega, Carmen; Felix, Luis M.; Sardao, Vilma A.; Colaco, Aura A.; Oliveira, Paula A.; Peixoto, Francisco P.. "Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity". Journal of Applied Toxicology 33 6 (2013): 434-443.
    Publicado • 10.1002/jat.1763
  40. Silva, T.; Teixeira, J.; Remião, F.; Borges, F.. "Alzheimer's disease, cholesterol, and statins: The junctions of important metabolic pathways". Angewandte Chemie - International Edition 52 4 (2013): 1110-1121. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872382364&partnerID=MN8TOARS.
    Publicado • 10.1002/anie.201204964
  41. Teixeira, J.; Soares, P.; Benfeito, S.; Gaspar, A.; Garrido, J.; Murphy, M.P.; Borges, F.. "Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold". Free Radical Research 46 5 (2012): 600-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859067775&partnerID=MN8TOARS.
    Publicado • 10.3109/10715762.2012.662593
  42. Teixeira, J. C. S.; Fernandes, M.; Bermudez, V. de Zea; Barbosa, P. C.; Rodrigues, L. C.; Silva, M. M.; Smith, M. J.. "Mg2+-doped poly(epsilon-caprolactone)/siloxane biohybrids". Electrochimica Acta 55 4 (2010): 1328-1332.
    Publicado • 10.1016/j.electacta.2009.06.024
Capítulo de livro
  1. Cagide, Fernando; Oliveira, Catarina; Teixeira, José; Oliveira, Paulo J.; Borges, Fernanda. "Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Gallic Acid to Mitochondria". In Methods in Molecular Biology, 161-172. Springer US, 2021.
    10.1007/978-1-0716-1262-0_10
  2. Amorim, Ricardo; Benfeito, Sofia; Teixeira, José; Cagide, Fernando; Oliveira, Paulo J.; Borges, Fernanda. "Targeting Mitochondria: The Road to Mitochondriotropic Antioxidants and Beyond". In Mitochondrial Biology and Experimental Therapeutics, 333-358. Springer International Publishing, 2018.
    Publicado • 10.1007/978-3-319-73344-9_16
  3. Amorim, R.; Benfeito, S.; Teixeira, J.; Cagide, F.; Oliveira, P.J.; Borges, F.. "Targeting mitochondria: The road to mitochondriotropic antioxidants and beyond". 333-358. 2018.
  4. Teixeira, José; Soares, Pedro; Benfeito, Sofia; Murphy, Michael P.; Oliveira, Paulo J.; Borges, Fernanda. "Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Caffeic Acid to Mitochondria". In Methods in Molecular Biology, 73-83. Springer New York, 2015.
    10.1007/978-1-4939-2288-8_6
Poster em conferência
  1. Débora Mena; Fernando Cagide; Ester Sofia Teixeira Benfeito; Luís Grilo; Daniela F. Silva; Paulo Pinheiro; Katarzyna Michalik; et al. "AntiOxCIN4 mitigates brain and skeletal muscle oxidative/nitrosative stress in the amyotrophic lateral sclerosis SOD1G93A mouse". Trabalho apresentado em Mitochondria in Aging, Cancer and Cell Death - MAC 2023, 2023.
  2. Caroline Veloso; Carina C. Magalhães; Ester Sofia Teixeira Benfeito; Cagide, Fernando; Rafael Silveira; Ivana Djedovic; Vera M. Mendes; et al. "Alterations in cardiac metabolism in Western Diet-induced metabolic syndrome: exploring the effects of mitochondriotropic antioxidant AntiOxCIN4". Trabalho apresentado em Mitochondria in Aging, Cancer and Cell Death - MAC 2023, 2023.
  3. Melim, Catarina; Amorim, Ricardo; Marques, Mário Pedro; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Teixeira, José; Oliveira, Paulo J.; Cabral, Célia. "Efeito hepatoprotetor de plantas do Vale do Côa (Portugal) num modelo celular de doença do fígado gordo não alcoolico (DFGNA)". Trabalho apresentado em XXVII Encontro Luso Galego de Química, 2023.
  4. Carina Sacoor; Márcia Aleixo; Ana Figueira; Hugo Vilhena; Paulo Oliveira; Teixeira, José; Liliana Montezinho. "Assessment of plasma zonulin levels in cats with inflammatory conditions: a pilot study". Trabalho apresentado em The World Small Animal Veterinary Association (WSAVS) congress,, 2023.
  5. Mena, Débora; Pedro Soares; Cagide, Fernando; Ester Sofia Teixeira Benfeito; Luis Grilo; Daniela F. Silva; Paulo Pinheiro; et al. "The mitochondria-targeted antioxidant AntiOxCIN4 attenuates brain and skeletal muscle oxidative/nitrosative stress in the amyotrophic lateral sclerosis SOD1G93A mouse". Trabalho apresentado em 57th Annual meeting of he European Society for Clinical Investigation, ”Envisioning the future of clinical and experimental investigation in Europe and beyond, 2023.
  6. Amorim, Ricardo; Catarina Melim; Pedro M. Marques; Carla Varela; Mariana I. Dias; L. Barros; Teixeira, José; Oliveira, Paulo J.; Célia Cabral. "Protective Effects of Equisetum ramosissimum Desf. against Palmitic Acid-Induced Lipid Accumulation and Mitochondrial Dysfunction in Human HepG2 cells". Trabalho apresentado em 57th Annual meeting of he European Society for Clinical Investigation, ”Envisioning the future of clinical and experimental investigation in Europe and beyond, 2023.
  7. Mena, Débora; Fernando Cagide; Sofia Benfeito; Pedro Soares; Luis Grilo; Paulo Pinheiro; Teixeira, José; et al. "The mitochondria-targeted antioxidant AntiOxCIN4 protects against cardiac oxidative/nitrosative stress in the amyotrophic lateral sclerosis SOD1G93A mouse.". Trabalho apresentado em 57th Annual meeting of he European Society for Clinical Investigation, ”Envisioning the future of clinical and experimental investigation in Europe and beyond, 2023.
  8. Amorim, Ricardo; Melim, Catarina; Marques, Mário P.; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Teixeira, José; Oliveira, Paulo; Célia Cabral. "Protective Effects of Equisetum ramosissimum Desf. Against Palmitic Acid-induced Lipid Accumulation and Mitochondrial Dysfunction in Human HepG2 Cells". Trabalho apresentado em 57th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2023.
  9. Amorim, Ricardo; Magalhães, Carina; Benfeito, Sofia ; Cagide, Fernando; Ludgero Tavares; Jones, John; Fernanda Borges; Paulo J. Oliveira; Teixeira, José. "Anticancer properties of AntiOxCIN6: repurposing the effects of a cytotoxic mitochondria-targeted caffeic acid antioxidant". Trabalho apresentado em International Meeting MitoPorto 2023, 2023.
  10. Barreiro, Sandra; Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Cagide, Fernando; Sequeira, Lisa; Teixeira, José; et al. "Nitrogen-based cationic carriers as a game changer in the development of mitochondriotropic antioxidants". Trabalho apresentado em MitoPorto - Mitochondrial physiology, redox biology, and genetics, 2023.
  11. Caroline Veloso; Carina C. Magalhães; Ester Sofia Teixeira Benfeito; Cagide, Fernando; Rafael Silveira; Ivana Djedovic; Vera Mendes; et al. "Effects of mitochondriotropic antioxidant AntiOxCIN4 on cardiac alterations in a mouse model for Western Diet-induced metabolic syndrome". Trabalho apresentado em In MitoPorto Mitochondrial physiology, redox biology, and genetics,, 2023.
  12. Teixeira, José; Ester Sofia Teixeira Benfeito; Carreira, Rodrigo Barreto ; André Barbosa; Amorim, Ricardo; Ludgero C. Tavares; John G. Jones; et al. "Mitochondriatargeted phenolic antioxidants AntiOxBEN2 and AntiOxCIN4 differentially impact energy metabolism in human dermal fibroblasts.". Trabalho apresentado em In MitoPorto Mitochondrial physiology, redox biology, and genetics, 2023.
  13. Amorim, Ricardo; Ines CM Simoes; Teixeira, José; Pedro Soares; Potes, Yaiza; Fernando Cagide; Ester Sofia Teixeira Benfeito; et al. "Mitochondria targeted antioxidant AntiOxCIN4 prevents hepatic steatosis by enhancing mitochondrial function and autophagy in Western diet (WD)-fed mice". Trabalho apresentado em In MitoPorto Mitochondrial physiology, redox biology, and genetics,, 2023.
  14. Grilo, Luís F.; Tocantins, Carolina; Diniz, Mariana S.; João D. Martins; Mena, Débora; Ricado Amorim ; Jelena Stevanovic-Silva; et al. "Modulação na comunicação endócrina fígado-tecido adiposo e no estado redox ao longo do envelhecimento da descendência pela prática de exercício materno durante uma gestação obesogénica". Trabalho apresentado em 19º Congresso Portugês de Diabetes, 2023.
  15. Carina Magalhães; Veloso, Caroline; Rafael Silveira; Ivana Djedovic; Vera M. Mendes; Karkucinska-Wieckowska, Agnieszka; Amorim, Ricardo; et al. Autor correspondente: Teixeira, José. "Antioxidante mitocondriotrópico AntiOxCIN4 previne as alterações cardíacas no contexto da doença do fígado gordo não-alcóolico". Trabalho apresentado em 19º Congresso Portugês de Diabetes, 2023.
  16. Gerardo, Heloísa; Amorim, Ricardo; Ines CM Simoes; Cavadas, Claudia; Wieckowski Mariusz R.; Oliveira, Paulo J.; Grãos, Mário; Teixeira, José. Autor correspondente: Teixeira, José. "O impacto da síndrome metabólica na interação entre metabolismo mitocondrial e mecanotransdução em cérebros de murganhos sujeitos a uma dieta ocidental". Trabalho apresentado em 19º Congresso Portugês de Diabetes, 2023.
  17. Amorim, Ricardo; Carina Magalhães; Benfeito, Ester; Tavares, Ludgero C.; Baldeiras, Ines; Jones, John G.; Maria Fernanda Martins Borges; Paulo J. Oliveira; Teixeira, José. Autor correspondente: Teixeira, José. "The mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 induces a Shift in metabolic profile towards a more glycolytic phenotype: Implications for lung cancer therapy". Trabalho apresentado em BEB day 2023, 2023.
  18. Amorim, Ricardo; Teixeira, José; Benfeito, Ester; Cagide, Fernando; Pedro Soares; Fernanda Borges; Oliveira, Paulo J.. "Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage". Trabalho apresentado em BEB day 2023, 2023.
  19. Gerardo, Heloísa; Amorim, Ricardo; Ines CM Simoes; Cavadas, Claudia; Wieckowski Mariusz R.; Oliveira, Paulo J.; Grãos, Mário; Teixeira, José. Autor correspondente: Teixeira, José. "Crosstalk between mechanotransduction and mitochondrial metabolism in the brain of Western diet-fd mice". Trabalho apresentado em BEB day 2023, 2023.
  20. Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Barreiro, Sandra; Cagide, Fernando; Silva, Catia; Teixeira, José; et al. "Synthesis and in vitro evaluation of versatile cell-penetrating mitochondriotropic antioxidants". Trabalho apresentado em XXVI Encontro Galego-Portugués de Química, 2022.
  21. Mena, Débora; Pedro Soares; Cagide, Fernando; Benfeito, Ester; Grilo, Luís F.; Daniela F. Silva; Valente, Pedro; et al. "The mitochondria-targeted antioxdiant AntiOxCIN4 is beneficial against oxidative/nitrosive stress in the amyotrophic lateral sclerosis SOD1G3A mouse". Trabalho apresentado em 56th Annual meeting of he European Society for Clinical Investigation, ”Promoting Biomedical Research, Equal Health and Environment in the post-COVID Syndemic Era, 2022.
  22. Amorim, Ricardo; Ines CM Simoes; Teixeira, José; Pedro Soares; Potes, Yaiza; Cagide, Fernando; Benfeito, Ester; et al. "Mitochondriotropic antioxidant AntiOxCIN4 improves mitochondrial function and prevents non-alcoholic fatty liver (NAFL)-associated autophagic blockage in western diet (WD)-fed mice". Trabalho apresentado em 56th Annual meeting of he European Society for Clinical Investigation, ”Promoting Biomedical Research, Equal Health and Environment in the post-COVID Syndemic Era, 2022.
  23. Victoria Ilina; Teixeira, José; Varela, Carla; Pedro Marques ; Sardão, Vilma; Melim, Catarina; Denis Baranenko; Oliveira, Paulo J.; Célia Cabral. "In vitro cardioprotective potential of Côa Valley (Portugal) plants extracts against lipotoxic insults". Trabalho apresentado em 56th Annual meeting of he European Society for Clinical Investigation, ”Promoting Biomedical Research, Equal Health and Environment in the post-COVID Syndemic Era, 2022.
  24. Mena, Débora; Pedro Soares; Cagide, Fernando; Benfeito, Ester; Grilo, Luís F.; Daniela F. Silva; Valente, Pedro; et al. "The Mitochondria-Targeted Antioxidant Antioxcin4 Protects Against Oxidative/Nitrosative Stress in the Amyotrophic Lateral Sclerosis SOD1GG3A Mouse". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  25. Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Ester; et al. "AntiOxCIN4 a new mitochondriotropic derivative based on the natural polyphenol caffeic acid reverts cellular and mitochondrial metabolic defects of fibroblasts from idiopathic Parkinson’s disease". Trabalho apresentado em 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease, 2021.
  26. Cláudia M. Deus; Susana P. Pereira; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Ester; et al. "A novel phenolic acid-based mitochondria-targeted antioxidant improves cellular responses to oxidative stress in fibroblasts from sporadic Parkinson’s disease patients". Trabalho apresentado em 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease, 2021.
  27. Carlos Fernandes; Duarte, Feliciano José Barreiras; Gonçalves, Beatriz; Veloso, Caroline; João D. Martins; Videira, Afonso J. C.; Pedro Soares; et al. Autor correspondente: Teixeira, José. "Improving Nature: targeting hydroxybenzoic acids to mitochondria for neuroprotection". Trabalho apresentado em 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease, 2021.
  28. João D. Martins; Duarte, Feliciano José Barreiras; Veloso, Caroline; Carlos Fernandes; Videira, Afonso J. C.; Benfeito, Ester; António Santos; et al. Autor correspondente: Teixeira, José. "Mitochondriiotropic antioxidants based on caffeic acid (MC4) protects H9c2 cardiomyoblasts against the cardiotoxicity of doxorubicin". Trabalho apresentado em 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease, 2021.
  29. Amorim, Ricardo; Ines CM Simoes; Veloso, Caroline; Adriana Marques-Carvalho; Simões, Rui F.; Theresa Tiel; Catarina M. Morais; et al. "High fat vs High sugar: the role of mitochondria on time-dependent hepatocellular cytotoxic effects". Trabalho apresentado em 54th Annual meeting of the European Society for Clinical Investigation, “COVID-19 edition, 2020.
  30. C. Teixeira; C. Marques ; M.C. Baptista; Jorge Pimenta; Teixeira, José; Cagide, Fernando; Borges, Fernanda; et al. "Beneficial effects of mitochondriotropic antioxidants on oocyte maturation and embryo production". Trabalho apresentado em 54th Annual meeting of the European Society for Clinical Investigation, “COVID-19 edition, 2020.
  31. Teixeira, José; Pedro Soares; Catarina Oliveira; Ester Sofia Teixeira Benfeito; Fernando Cagide; Carlos Fernandes; Ricardo Amorim; Paulo J. Oliveira; Fernanda Borges. "From nature inspiration to multi-target small molecules: upgrading the activity of dietary cinnamic". Trabalho apresentado em Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action, 2019.
  32. Teixeira, José; Catarina Oliveira; Donatella Bagetta; Fernando Cagide; Ricardo Amorim; Tiago Silva; Jorge Garrido; et al. "Benzoic acid-derived Nitrones: a new class of acetylcholinesterase inhibitors and potential neuroprotective agents". Trabalho apresentado em Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action, 2019.
  33. Teixeira, José; Ricardo Amorim; Caroline Veloso; Paulo. J. Oliveira. "Non-alcoholic fatty liver disease (NAFLD) in vitro: Characterization and comparison of several in vitro models using human hepatic cells". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  34. Teixeira, José; Rodrigo Carreira; Ricardo Amorim; Ana Catarina Gomes Oliveira; Fernando Cagide; Paulo. J. Oliveira. "Metabolic remodeling of dermal fibroblasts by a novel mitochondria-targeted hydroxybenzoic acid derivative". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  35. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Carlos Fernandes; Fernando Cagide; Ricardo Amorim; Jorge Garrido; et al. "Design and synthesis of mitochondriotropic antioxidants based on dietary scaffold endowed with neuropretective activity and BBB permeability". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  36. Teixeira, José; Caroline Veloso; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Fernanda Borges; Paulo. J. Oliveira. "Mitochondriotropic antioxidants based on dietary phenolic acids: Potential effect against chemical-induced skin senescence". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  37. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Ludgero C. Tavares; John G. Jones; Fernanda Borges; Paulo. J. Oliveira. "Unraveling the mechanism throughout mitochondriotropic cinnamic acid antioxidants increase cellular stress response in HepG2 cells". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  38. Teixeira, José; André Barbosa; Ricardo Amorim; Ludgero C. Tavares; John G. Jones; Caroline Veloso; Sofia Benfeito; et al. "Redox signaling and metabolism modulation of human fibroblasts by mitochondria-targeted polyphenolic constructs". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, 2019.
  39. Teixeira, José; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Tiago Silva; Jorge Garrido; Fernando Remião; et al. "Hydroxybenzoic acid derivatives as dual-target ligands: Mitochondriotropic antioxidants and cholinesterase inhibitors". Trabalho apresentado em MuTaLig COST action, 2018.
  40. Teixeira, José; Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; Paulo. J. Oliveira; Fernanda Borges. "Modulating the cytotoxicity of a mitochondriotropic antioxiant by a flexible PEGylation strtegy". Trabalho apresentado em MuTaLig COST action, 2018.
  41. Teixeira, José; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Carlos Fernandes; Ricardo Amorim; Jorge Garrido; et al. "Fine-tuning the neuroprotective and blood-brain barrier permeability profile of dietary based mitochondria-targeted antioxidants.". Trabalho apresentado em MuTaLig COST action, 2018.
  42. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Fernanda Borges; Paulo. J. Oliveira. "Effects of mitochondria-targeted antioxidants in human hepatic cells: a possible therapy for hepatic steatosis". Trabalho apresentado em MuTaLig COST action, 2018.
  43. Teixeira, José; Caroline Veloso; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Fernanda Borges; Paulo. J. Oliveira. "Skin aging and mitochondriotropic antioxidants based on dietary hydroxycinnamic acids". Trabalho apresentado em MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium, 2018.
  44. Teixeira, José; Rodrigo Carreira; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Fernanda Borges; Paulo. J. Oliveira. "Effect of multi-functional mitochondria-targeted antioxidants in human skin fibroblasts". Trabalho apresentado em MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium, 2018.
  45. Teixeira, José; Cláudio F. Costa; Sonia L. C. Pinho; Vilma A. Sardão; Paulo. J. Oliveira; Teresa Cunha-Oliveira. "Standardization and characterization of cell culture conditions for OXPHOS induction and for mitochondrial health studies im human fibriblasts". Trabalho apresentado em MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium, 2018.
  46. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Paulo. J. Oliveira; Fernanda Borges. "Mitochondriotropic cinnamic acid antioxidants improves steatosis in a Non-Alcoholic Fatty Liver Disease (NAFLD) cell model". Trabalho apresentado em MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium, 2018.
  47. Teixeira, José; Ricardo Amorim; Inês Baldeiras; Sofia Benfeito; Fernando Cagide; Jorge Garrido; Paulo. J. Oliveira; Fernanda Borges. "Mitochondriotropic cinnamic acid antioxdiants increase celular stress responses in HepG2 cells: Involvement of (mt)ROS signaling?". Trabalho apresentado em MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium, 2018.
  48. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Carlos Fernandes; Fernando Cagide; Ricardo Amorim; Jorge Garrido; et al. "Restoring acetylcholine levels an shielding mitochondria as a multi-target strategy for neurodegenerative diseases". Trabalho apresentado em VIII Meeting of the Paul Ehrlich Euro-PhD Network, 2018.
  49. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Paulo. J. Oliveira; Fernanda Borges. "Mitochondriotropic cinnamic acid antioxidants increase cellular stress response in HepG2 cells: involvement of mitochondrial ROS signaling in a possible therapy for hepatic steatosis". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, 2018.
  50. Teixeira, José; Caroline Veloso; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Fernanda Borges; Paulo J. Oliveira. "Mitochondriotropic antioxidants based on dietary phenolic acids as modulators of oxidative stress on skin fibroblasts". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, 2018.
  51. Teixeira, José; Ricardo Amorim; Rodrigo Carreira; Fernando Cagide; Sofia Benfeito; Fernanda Borges; Paulo J. Oliveira. "Effects of multi-operational mitochondria-targeted antioxidants in human hepatic cells: promising drugs for liver disease". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, 2018.
  52. Teixeira, José; Fernando Cagide; Sofia Benfeito; Renata Silva; Fernando Remião; Jorge Garrido; Paulo. J. Oliveira; Eugenio Uriarte; Fernanda Borges. "Cationic derivatives based on natural scaffolds as dual-target agentes for Alzheimer’s disease". Trabalho apresentado em MuTaLig COST action, 2018.
  53. Teixeira, José; Ricardo Amorim; Rodrigo Carreira; Sofia Benfeito; Fernando Cagide; Paulo. J. Oliveira; Fernanda Borges. "Mitochondria-targeted cinnamic antioxidants incresae celular stress response through modulation of mitochondria function/activity". Trabalho apresentado em In MuTaLig COST action, 2018.
  54. Teixeira, José; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Tiago Silva; Jorge Garrido; Fernando Remião; et al. "Hydroxybenzoic acid-based mitochondriotropic antioxidants as cholinesterase inhibitors". Trabalho apresentado em EpiChemBio and MuTaLig COST actions joint meeting, 2017.
  55. Teixeira, José; Sofia Benfeito; Fernando Cagide; Ricardo Amorim; Fernando Remião; Eugénio Uriarte; Paulo. J. Oliveira; Fernanda Borges. "Targeted delivery of mitocondriotropics derivatives: a new therapeutic approach for oxidative stress related diseases". Trabalho apresentado em In EpiChemBio and MuTaLig COST actions joint meeting, 2017.
  56. Teixeira, José; Carlos Fernandes; Ricardo Amorim; Paulo. J. Oliveira; Fernando Remião; Fernanda Borges. "Synthesis of a mitochondriotropic antioxidante based on pegylation process". Trabalho apresentado em EpiChemBio and MuTaLig COST actions joint meeting, 2017.
  57. Teixeira, José; Ricardo Amorim; Katia Santos; Pedro Soares; Teresa Serafim; Vilma A. Sardão; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira. "– In vitro characterization of potential biological applications of MitoK3, a novel mitochondriotropic menadione derivative". Trabalho apresentado em EpiChemBio and MuTaLig COST actions joint meeting, 2017.
  58. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Jorge Garrido; Paulo. J. Oliveira; Fernanda Borges. "Effects of different targeting cations on the toxicity profile of mitochondriotropic-hydroxycinnamic antioxidants". Trabalho apresentado em MitoPorto: Advances in Mitochondrial Research International Symposium, 2017.
  59. Teixeira, José; Ricardo Amorim; Katia Santos; Pedro Soares; Teresa Serafim; Vilma A. Sardão; Jorge Garrido; Fernanda Borges; Paulo. J. Oliveira. "Improvement of menadione cytotoxic potential by a mitochondria.targeted strategy". Trabalho apresentado em In MitoPorto: Advances in Mitochondrial Research International Symposium, 2017.
  60. Gomes, Cátia; Teixeira, José; Oliveira, Paulo J.; Ferreira, Isabel C. F. R.; Ramalho-Santos, João; Azul, Anabela Marisa. "Effects of edible mushroom extracts on palmitic acid-induced lipotoxicity in human HepG2 cells". Trabalho apresentado em MitoPorto - Advances in Mitochondrial Research: https://sites.google.com/site/mitoporto2018/, 2017.
  61. Teixeira, José; Catarina Oliveira; Ricardo Amorim; Tiago Silva; Fernando Cagide; Jorge Garrido; Paulo J. Oliveira; Paula B. Andrade; Fernanda Borges. "Targeting dietary phenolic acids to mitochondria: improving hydroxybenzoic acids antioxidant properties". Trabalho apresentado em 49th Annual Meeting of the European Society for Clinical Investigation, 2015.
  62. Teixeira, José; Katia Santos; Ricardo Amorim; Fernando Cagide; Fernanda Borges; Paulo. J. Oliveira. "New paradigms in anticancer combined therapy: targeting dietary antioxidants to mitochondria". Trabalho apresentado em 49th Annual Meeting of the European Society for Clinical Investigation, 2015.
  63. Teixeira, José; Tiago Silva; Sofia Benfeito; Alexandra Gaspar; E. Manuela Garrido; Jorge Garrido; Fernanda Borges. "Exploring natural profits: development of novel and potente galloylcinnamic hybrids Lipophilic antioxidants". Trabalho apresentado em 16th SFRRI Biennial Meeting, 2012.
  64. Teixeira, José; Tiago Silva; Igor Encarnação; João Amorim; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Overcoming pharmacokinetics problems associated with antioxidant Therapy: development of Lipophilic derivatives based on natural hydroxycinnamic acids". Trabalho apresentado em 16th SFRRI Biennial Meeting, 2012.
  65. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Opening a new avenue in neurodegenerative Therapy: Lead optimization of a mitochondria-targeted cinnamic antioxidants". Trabalho apresentado em 16th SFRRI Biennial Meeting, 2012.
  66. Teixeira, José; Catarina Oliveira; Sofia Benfeito; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Bridging the gap between Nature and antioxidants setbacks: delivering hydroxybenzoic acids to mitochondria". Trabalho apresentado em 16th SFRRI Biennial Meeting, 2012.
  67. Teixeira, José; Tiago Silva; João Amorim; Igor Encarnação; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "New solutions for an old problem: Surpassing the pharmacokinetic drawbacks of natural phenolic antioxidants". Trabalho apresentado em 22nd International Symposium on Medicinal Chemistry, 2012.
  68. Teixeira, José; Fernanda Borges; Alexandra Gaspar; Tiago Silva; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; et al. "Striving for success in antioxidant therapy for neurodegenerative diseases: current status and future prospects". Trabalho apresentado em 22nd International Symposium on Medicinal Chemistr, 2012.
  69. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Opening a new avenue in neurodegenerative therapy: Lead optimization of a mitochondria-targeted cinnamic antioxidant". Trabalho apresentado em 5º Meeting of younger researchers of University of Porto (IJUP12), 2012.
  70. Teixeira, José; Catarina Oliveira; Sofia Benfeito; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Opening a new avenue in neurodegenerative therapy: development of mitochondria-targeted antioxidants based on benzoic scaffold". Trabalho apresentado em 5º Meeting of younger researchers of University of Porto (IJUP12), 2012.
  71. Teixeira, José; Sofia Benfeito; Alexandra Gaspar; Jorge Garrido; Michael P. Murphy; Fernanda Borges. "Mitochondria-targeted Cinnamic Antioxidants: Novel Promising Drugs for Treatment of Alzheimer’s diseas". Trabalho apresentado em 6th Drug discovery for neurodegeneration conference: an intensive course on translating research into drugs, 2012.
  72. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Targeting phenolic Antioxidants to Mitochondria: Synthesis and Characterization of novel Triphenylphosphonium-conjugated Lipophilic Cinnamic Derivatives". Trabalho apresentado em In 2nd Iberic Meeting on Medicinal Chemistry: G Protein-Coupled Receptors and Enzymes in Drug Discovery (2IMMC), 2011.
  73. Teixeira, José; Alexandra Gaspar; Jorge Garrido; Jorge M. A. Oliveira; Michael P. Murphy; Fernanda Borges. "New mitochondria-targeted antioxidants based on cinnamic scaffold for neurodegenerative disease therapy". Trabalho apresentado em 2nd Iberic Meeting on Medicinal Chemistry: G Protein-Coupled Receptors and Enzymes in Drug Discovery (2IMMC), 2011.
  74. Teixeira, José; Sofia Benfeito; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Lipophilic Cinnamic Cations: New mitochondria-targeted antioxidants for neurodegenerative disease therapy". Trabalho apresentado em 4º Meeting of Young Researchers of University of Porto (IJUP’11), 2011.
  75. Teixeira, José; Mariana Fernandes; Verónica de Zea Bermudez. "Spectroscopic analysis of biohybrids electrolytes doped with KCF3SO3 and Mg(CF3SO3)2". Trabalho apresentado em XII International Symposium on Polymer Electrolytes (ISPE-12), 2010.
  76. Teixeira, José; Vilma A. Sardão; Daria S. Santos; Maria M. Oliveira; Vasconcelos-Nobrega, Carmen; Luis F. De la Cruz; Aura Colaço; Paula A. Oliveira; Francisco P. Peixoto. "Evaluation of liver mitochondrial bioenergetics functions during NButyl-N-(4-hydroxybutyl) nitrosamine (BBN) metabolization". Trabalho apresentado em Mitochondria: Between Life and Death” – International Courses on Toxicology, 2009.
  77. Teixeira, José; Mariana Fernandes; Verónia de Zea Bermudez; Paula C. Barbosa; Luisa Rodrigues; Maria M. Silva; Michael J. Smith. "Mg2+-Doped poly (e-Caprolactone)/Siloxane Biohybrid Electrolytes". Trabalho apresentado em 11th International Symposium on Polymer Electrolytes, 2008.
Resumo em conferência
  1. Magalhães, Carina; Veloso, Caroline; Rafael Silveira; Ivana Djedovic; Mendes, Vera M; Agnieszka Karkucinska-Wieckowska; Amorim, Ricardo; et al. "The mitochondriotropic antioxidant AntiOxCIN4 prevents NAFLD/NASH-induced cardiac alterations". Trabalho apresentado em European Society for Clinical Investigation, Praga, 2023.
  2. Gerardo, Heloísa; Amorim, Ricardo; Teixeira, José. "Exploring the impact of metabolic syndrome on brain stiffness and metabolism: Insights from in vivo and in vitro experiments". Trabalho apresentado em MitoPorto 2023: Mitochondrial physiology, redox biology, and genetics, Porto, 2023.
    Publicado
  3. Veloso, Caroline; Magalhães, Carina; Benfeito, Sofia ; Cagide, Fernando; Rafael Silveira; Ivana Djedovic; Mendes, Vera M; et al. "Alterations in cardiac metabolism in Western Diet-induced metabolic syndrome: exploring the effects of AntiOxCIN4, a mitochondriotropic antioxidant". Trabalho apresentado em International Meeting MitoPorto 2023, 2023.
  4. Magalhães, Carina; Veloso, Caroline; Rafael Silveira; Ivana Djedovic; Mendes, Vera M; Agnieszka Karkucinska-Wieckowska; Amorim, Ricardo; et al. "Antioxidante mitocondriotrópico AntiOxCIN4 previne as alterações cardíacas no contexto de Fígado gordo não-alcoólico". Trabalho apresentado em 19º Congresso Português de Diabetes, 2023.
  5. Amorim, Ricardo; Magalhães, Carina; Benfeito, Sofia ; Ludgero Tavares; Baldeiras, Ines; Jones, John; Fernanda Borges; Paulo J. Oliveira; Teixeira, José. "The mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 lowers mitochondrial metabolism while upregulating glycolysis in human HepG2 cells". Trabalho apresentado em 53rd Meeting of the Portuguese Society of Pharmacology, 2023.
  6. Melim, Catarina; Teixeira, José; Varela, Carla; Marques, Mário; Sardão, Vilma; Oliveira, Paulo; Célia Cabral. "Potential of Côa Valley (Portugal) Plants Extracts in Cell Model for Hepatic Lipid Toxicity". Trabalho apresentado em 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Bari, 2022.
    Publicado
  7. Teixeira Camila; Marques CC; Baptista MC; Pimenta, J.; Teixeira, José; Cagide F; Borges, F; et al. "Effect of a new mitochondriotropic antioxidant on oocyte maturation and embryo production". Trabalho apresentado em 71st Annual Meeting of European Federation of Animal Science (EAAP), Porto, 2020.
    Publicado
  8. Pereira, Ricardo; Costa, Joana; Rodrigues, Rui; Villa, Caterina; Teixeira, José; Mafra, Isabel; Vicente, António A.. "Assessment of electrical effects of ohmic heating on structural and immunoreactivity properties of bovine betalactoglobulin". Trabalho apresentado em 8th International Symposium on Delivery of Functionality in Complex Food Systems, Porto, 2019.
    Publicado
  9. Teixeira, José; Rodrigo Carreira; Ricardo Amorim; Catarina Oliveira; Fernando Cagide; Paulo J. Oliveira. "Metabolic remodeling of dermal fibroblasts by a novel mitochondria-targeted hydroxybenzoic acid derivative". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  10. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Carlos Fernandes; Fernando Cagide; Ricardo Amorim; Jorge Garrido; et al. "Design and synthesis of mitochondriotropic antioxidants based on dietary scaffold endowed with neuropretective activity and BBB permeability". Trabalho apresentado em In 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  11. Teixeira, José; Caroline Veloso; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Fernanda Borges; Paulo J. Oliveira. "Mitochondriotropic antioxidants based on dietary phenolic acids: Potential effect against chemical-induced skin senescence". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  12. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Ludgero C. Tavares; John G. Jones; Fernanda Borges; Paulo J. Oliveira. "Unraveling the mechanism throughout mitochondriotropic cinnamic acid antioxidants increase cellular stress response in HepG2 cells". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  13. Teixeira, José; André Barbosa; Ricardo Amorim; Ludgero C. Tavares; John G. Jones; Caroline Veloso; Sofia Benfeito; et al. "Redox signaling and metabolism modulation of human fibriblasts by mitochondria-targeted polyphenolic constructs". Trabalho apresentado em 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  14. Teixeira, José; Ricardo Amorim; Caroline Veloso; Paulo J. Oliveira. "Non-alcoholic fatty liver disease (NAFLD) in vitro: Characterization and comparison of several in vitro models using human hepatic cells". Trabalho apresentado em In 53rd Annual Meeting of the European Society for Clinical Investigation “The Clocks of Metabolism and Disease, Coimbra, 2019.
    Publicado
  15. Teixeira, José; Ricardo Amorim; Rodrigo Carreira; Fernando Cagide; Sofia Benfeito; Fernanda Borges; Paulo J. Oliveira. "Effects of multi-operational mitochondria-targeted antioxidants in human hepatic cells: promising drugs for liver disease". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, Barcelona, 2018.
    Publicado
  16. Teixeira, José; Ricardo Amorim; Sofia Benfeito; Fernando Cagide; Paulo J. Oliveira; Fernanda Borges. "Mitochondriotropic cinnamic acid antioxidants increase cellular stress response in HepG2 cells: involvement of mitochondrial ROS signaling in a possible therapy for hepatic steatosis". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, Barcelona, 2018.
    Publicado
  17. Teixeira, José; Caroline Veloso; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; Fernanda Borges; Paulo J. Oliveira. "Mitochondriotropic antioxidants based on dietary phenolic acids as modulators of oxidative stress on skin fibroblasts". Trabalho apresentado em 52th Annual Meeting of the European Society for Clinical Investigation “Precision Medicine for Healthy Ageing, Barcelona, 2018.
    Publicado
  18. Teixeira, José; Ricardo Amorim; Katia Santos; Pedro Soares; Teresa Serafim; Vilma A. Sardão; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira. "MitoK3, a novel mitochondriotropic menadione derivative with cytotoxic effects on cancer cells". Trabalho apresentado em 51th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Génova, 2017.
    Publicado
  19. Teixeira, José. "The hormetic role of redox-active polyphenols in human health and disease". Trabalho apresentado em 10th World Congress on Polyphenols Applications, Porto, 2016.
    Publicado
  20. Teixeira, José; Farhan Basit; Paulo J. Oliveira; Peter H.G.M. Willems; Jori Joosten-Wagenaars; Fernando Cagide; Sofia Benfeito; Fernanda Borges; Werner J.H. Koopman. "Mitohormesis: An attempt by targeting hydroxycinnamic acid derivatives to mitochondria". Trabalho apresentado em 50th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Paris, 2016.
    Publicado
  21. Teixeira, José; Catarina Oliveira; Ricardo Amorim; Tiago Silva; Fernando Cagide; Jorge Garrido; Paulo J. Oliveira; Paula B. Andrade; Fernanda Borges. "Targeting dietary phenolic acids to mitochondria: improving hydroxybenzoic acids antioxidant properties". Trabalho apresentado em 49th Annual Meeting of the European Society for Clinical Investigation, Cluj Napoca, 2015.
    Publicado
  22. Teixeira, José; Katia Santos; Ricardo Amorim; Fernando Cagide; Fernanda Borges; Paulo J. Oliveira. "New paradigms in anticancer combined therapy: targeting dietary antioxidants to mitochondria". Trabalho apresentado em 49th Annual Meeting of the European Society for Clinical Investigation, Cluj Napoca, 2015.
    Publicado
  23. Teixeira, José; Sofia Benfeito; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Michael P. Murphy; Paulo J. Oliveira; Fernanda Borges. "Development of novel systems to delivery natural antioxidants to mitochondria: MitoCIN’s as a case study". Trabalho apresentado em 47th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Albufeira, 2013.
    Publicado
  24. Teixeira, José; Tiago Silva; Igor Encarnação; João Amorim; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Overcoming pharmacokinetics problems associated with antioxidant Therapy: development of Lipophilic derivatives based on natural hydroxycinnamic acids". Trabalho apresentado em 16th SFRRI Biennial Meeting, Londres, 2012.
    Publicado
  25. Teixeira, José; Sofia Benfeito; Catarina Oliveira; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Opening a new avenue in neurodegenerative Therapy: Lead optimization of a mitochondria-targeted cinnamic antioxidants". Trabalho apresentado em 16th SFRRI Biennial Meeting, Londres, 2012.
    Publicado
  26. Teixeira, José; Catarina Oliveira; Sofia Benfeito; Pedro Soares; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "Bridging the gap between Nature and antioxidants setbacks: delivering hydroxybenzoic acids to mitochondria". Trabalho apresentado em 16th SFRRI Biennial Meeting, Londres, 2012.
    Publicado
  27. Teixeira, José; Tiago Silva; Sofia Benfeito; Alexandra Gaspar; E. Manuela Garrido; Jorge Garrido; Fernanda Borges. "Exploring natural profits: development of novel and potente galloylcinnamic hybrids Lipophilic antioxidants". Trabalho apresentado em 16th SFRRI Biennial Meeting, Londres, 2012.
    Publicado
  28. Teixeira, José; Fernanda Borges; Alexandra Gaspar; Tiago Silva; Fernando Cagide; Sofia Benfeito; Catarina Oliveira; et al. "Striving for success in antioxidant therapy for neurodegenerative diseases: current status and future prospects". Trabalho apresentado em 22nd International Symposium on Medicinal Chemistry, Berlim, 2012.
    Publicado
  29. Teixeira, José; Tiago Silva; João Amorim; Igor Encarnação; Alexandra Gaspar; Jorge Garrido; Fernanda Borges. "New solutions for an old problem: Surpassing the pharmacokinetic drawbacks of natural phenolic antioxidants". Trabalho apresentado em 22nd International Symposium on Medicinal Chemistry, Berlim, 2012.
    Publicado
Tese / Dissertação
  1. Teixeira, José. "Targeting dietary antioxidants to mitochondria: regulating mitochondrial radical production and redox signaling to improve human health". Doutoramento, Universidade do Porto Faculdade de Farmácia, 2016.
  2. Teixeira, José. "DEVELOPMENT OF MITOCHONDRIA-TARGETED ANTIOXIDANTS BASED ON CINNAMIC SCAFFOLD AS A THERAPEUTIC SOLUTION FOR NEURODEGENERATIVE DISEASES". Mestrado, Universidade do Porto Faculdade de Ciências, 2011.

Propriedade Intelectual

Patente
  1. Teixeira, José; Maria Fernanda Martins Borges; Paulo Jorge Gouveia Simões da Silva Oliveira; Fernando Cagide Fagin; Ana Catarina Gomes Oliveira. 2018. "HYDROXYBENZOIC ACID DERIVATIVES, METHODS AND USES THEREOF".
  2. Teixeira, José; Maria Fernanda Martins Borges; Paulo Jorge Gouveia Simões da Silva Oliveira; Fernando Cagide Fagin; Ester Sofia Teixeira Benfeito. 2018. "HYDROXYCINNAMIC DERIVATIVES, METHODS AND USES THEREOF". Portugal.
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/12/02 AntiOxCIN6 potentiates cisplatin anticancer therapy by lowering mitochondrial metabolism while upregulating energetic glycolytic dependence Mitochondria in Aging, Cancer and Cell Death - MAC 2023
(Coimbra, Portugal)
2023/07/06 Mitochondria-targeted antioxidant based on hydroxycinnamic acid AntiOxCIN4 improvesd liver steatosis in Western diet-fed mice: the role of Nrf2- mediated cell signalling pathways In 9th International Congress of Pathophysiology and 5th Congress of Physiological Sciences of Serbia
Physiological Sciences of Serbia (Belgrade, Sérvia)
2023/07/04 Targeting Mitochondria: Past and Present. In 9th International Congress of Pathophysiology and 5th Congress of Physiological Sciences of Serbia
Physiological Sciences of Serbia (Belgrado, Sérvia)
2023/06/08 The mitochondriotropic antioxidant AntiOxcin4 prevents NAFLD/Nash-induced cardiac alterations 57th Annual meeting of he European Society for Clinical Investigation, ”Envisioning the future of clinical and experimental investigation in Europe and beyond
European Society for Clinical Investigation (Praga, República Checa)
2023/06/07 Alterations in brain stiffness and metabolism in Western Diet-induced metabolic syndrome: Exploring the interplay between mechanotransduction and metabolic pathways. 57th Annual meeting of he European Society for Clinical Investigation, ”Envisioning the future of clinical and experimental investigation in Europe and beyond
European Society for Clinical Investigation (Prague, República Checa)
2023/05/12 AntiOxCIN4 protects against brain and skeletal muscle oxidative/nitrosative stress in the amyotrophic lateral sclerosis SOD1G93A mouse. MitoPorto - Mitochondrial physiology, redox biology, and genetics
(Porto, Portugal)
2023/05/12 Exploring the impact of metabolic syndrome on brain stiffness and metabolism: Insights from in vivo and in vitro experiments In MitoPorto Mitochondrial physiology, redox biology, and genetics,
(Porto, Portugal)
2023/03/16 O antioxidante mitocondriotrópico AntiOxCIN4 melhora a função mitocondrial e previne o bloqueio autofágico associado à esteatose hepática em ratinhos alimentados com dieta obesogénica. 19º Congresso Portugês de Diabetes
Sociedade Portuguesa Diabetes (Algarve, Portugal)
2023/02/01 The mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 lowers mitochondrial metabolism while upregulating glycolysis in human HepG2 cells Sociedade Portuguesa de Farmacologia (SPF) Meeting at University of Coimbra
Sociedade Portuguesa de Farmacologia (SPF) (Coimbra, Portugal)
2022/06/08 Mitochondriotropic Antioxidants Based on Hydroxycinnamic Acids Activates Nrf2-Mediated Cell Signalling Responses to Oxidative Stress: Implications in Non-Alcoholic Fatty Liver Disease (NAFLD) 56th Annual meeting of he European Society for Clinical Investigation, ”Promoting Biomedical Research, Equal Health and Environment in the post-COVID Syndemic Era
European Society for Clinical Investigation (Bari, Itália)
2022/06/08 Potential of Côa Valley (Portugal) plants extracts in cell model for hepatic lipid toxicity 56th Annual meeting of he European Society for Clinical Investigation, ”Promoting Biomedical Research, Equal Health and Environment in the post-COVID Syndemic Era
European Society for Clinical Investigation (Bari, Itália)
2021/12/09 Protective Effects of the Mitochondria-Targeted Antioxidant Antioxcin4 Against Oxidative Stress in the Amyotrophic Lateral Sclerosis SOD1G93A Mouse 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity
(International online event)
2021/10/13 Reverting mitochondrial impairment in skin fibroblasts from Parkinson’s Disease patients using a mitochondria-targeted antioxidant AntiOxCIN4 23rd International Conference on Oxidative Stress reduction, redox homeostasis and antioxidants
Redox Medicine Society
2021/08/04 Toxicological and Pharmacological effects of new molecules International Virtual Conference on Biology in 21st Century at Kongunadu Arts and Science College
Kongunadu Arts and Science College (Tamil Nadu, Índia)
2021/06/09 Decrypting the Nrf2-dependent antioxidant mechanism of action behind the beneficial effcts of the mitochondriotropic cinnamic acid AntiOxCIN4 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease
European Society for Clinical Investigation
2021/06/09 Impacts of a novel mitochondria-directed antioxidant on bovines per function and in vitro embryo deveploment 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease
European Society for Clinical Investigation
2021/06/09 Mitochondria-targeted hydroxybenzoic acids prevent Oxidative damage to normal human dermal fibroblasts 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease
European Society for Clinical Investigation
2021/06/09 Time dependente effect of Western Diet on mitochondrial physiology in a mouse model of non-alcohoic fattyliver disease 55th Annual meeting of he European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease
European Society for Clinical Investigation
2020/11/05 MITOTAG: Development of a new generation of antioxidants for skin aging In 11th International Conference on Skin Ageing & Challenges
Skin Ageing & Challenges
2020/03/05 Mitochondriotropic cinnamic acid antioxidant improves cellular resistance to stress MuTaLig COST action
(Izmir, Turquia)
2019/11/29 Etiopatogenia da doença de fígado gordo não alcoólico 32º Curso de Doenças Hepatobiliares “Hepatologia 2019
Hepatologia do Centro Hospitalar Universidade de Coimbra (Coimbra, Portugal)
2019/10/27 Antioxdant, hormetic-like properties of AntiOxCIN4, a novel hydroxycinnamic acid-based mitochondria-targeted agent 10th Targeting Mitochondria Congress
World Mitochondria Society (Berlim, Alemanha)
2019/06/15 PEGylation technology – the second chance for non-bioavailable drug candidates
Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action (Catanzaro , Itália)
2019/06/14 Design and development of multi-target agents for neurodegenerative diseases Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action,
University "Magna Græcia" of Catanzaro (Catanzaro, Itália)
2019/06/13 PEGylation technology – the second chance for non-bioavailable drug candidates Meeting of the Paul Ehrlich Euro-PhD Network - MuTaLig COST action
MuTaLig COST action (Catanzaro, Itália)
2019/05/09 The distribution of saturated, monounsaturated and polyunsaturated fatty acids in the sn2 and sn1,3 positions of hepatic triglyceride is not homogenous In 7th EASD NAFLD Study Group Meeting of the European Association for the Study of Diabetes
European Association for the Study of Diabetes (Lisboa, Portugal)
2019/03/15 Desenvolvimento de uma nova geração de antioxidantes direcionados para a mitocôndria: a importância de moléculas de origem natural Jornadas da Ciência at University of Minho
Universidade do Minho (Braga, Portugal)
2019/02/22 Improving the activity of dietary cinnamic and benzoic acids for the treatment of neurodegenerative disorders 26th Young research fellows meeting
French Medicinal Chemistry Society (SCT) (Paris, França)
2019/02/08 Mitochondriotropic antioxidants based on dietary hydroxycinnamic acids as an attempt to reduce skin aging Sociedade Portuguesa de Farmacologia (SPF) Meeting at University of Porto
Sociedade Portuguesa de Farmacologia (SPF) (Porto, Portugal)
2019/02/08 Targeting Phenolic Dietary Antioxidants to Mitochondria to Modulate Redox Signaling and Metabolism Sociedade Portuguesa de Farmacologia (SPF) Meeting at University of Porto
Sociedade Portuguesa de Farmacologia (SPF) (Porto, Portugal)
2018/10/23 Mitochondria-targeted Antioxidants in Human Hepatic Cells: A Conceivable Therapy for Non-Alcoholic Fatty Liver Disease 9th Targeting Mitochondria
World Mitochondria Society (Berlim, Alemanha)
2018/10/22 Mitochondrial remodeling after forcing OXPHOS in human skin fibroblasts Mitochondrial DNA and Derived Peptides in Health and Disease
University of Coimbra (Coimbra, Portugal)
2018/10/18 History in the Making: development of multi-target-directed ligands for Alzheimer’s disease that modulate oxidative stress/ mitochondria quality and the cholinergic system MuTaLig COST action
University of Malta (Valletta , Malta)
2018/07/14 Benzoic acid as a valid scaffold for the development of dual-target directed drugs for Alzhemier’s disease VIII Meeting of the Paul Ehrlich Euro-PhD Network
Universidade do Porto (Porto , Portugal)
2018/03/16 Development of multi-target agentes based on hydroxybenzoic acid scaffold endowed with mitochondriotropic antioxidante and cholinesterase inhibitory activity MuTaLig COST action
Universidad de la Laguna (Tenerife, Espanha)
2018/03/15 Mitochondriotropic antioxidants based on cinnamic acid derivatives increase celular stress responses in HepG2 cells MuTaLig COST action
Universidad de la Laguna (Tenerife, Espanha)
2018/02/26 Skin mitohormesis by targeting hydroxycinnamic acid derivatives to mitochondria 9th International Conference on Skin Ageing & Challenges
International Society of Antioxidants in Nutrition and Health (Porto, Portugal)
2017/08/27 Disruption of mitochondrial function as mechanism for anti-cancer Activity of a novel mitochondriotropic menadione derivative 7th Meeting of the Paul Ehrlich Euro-PhD Network
Institute of Applied Synthetic Chemistry (Viena, Áustria)
2017/08/27 Development of hybrid antioxidant and cholinesterase agents for Alzheimer’s disease 7th Meeting of the Paul Ehrlich Euro-PhD Network
Institute of Applied Synthetic Chemistry (Viena, Áustria)
2017/05/18 MitoK3, a novel mitochondriotropic menadione derivative with cytotoxic effects on cancer cells 51th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (ESCI) (Génova, Itália)
2016/11/20 Targeting dietary antioxidants to mitochondria as a therapeutic solution for mitochondrial oxidative stress related diseases VI Meeting of the Paul Ehrlich Euro-PhD Network
Pázmány Péter Catholic University (Budapest) and to the Semmelweis University (Budapest) (Budapeste , Hungria)
2016/07/01 The hormetic role of redox-active polyphenols in human health and disease In 10th World Congress on Polyphenols Applications
International Society of Antioxidants (Porto , Portugal)
2016/04/27 Mitohormesis: An attempt by targeting hydroxycinnamic acid derivatives to mitochondria 50th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (ESCI (Paris, França)
2016/03/29 Da Inovação ao Negócio Tecnológico: a história evolutiva da MitoDIETS IX Meeting of Biochemistry at University of Trás-os-Montes e Alto Douro
Universidade de Trás os Montes e Alto Douro (Vila Real , Portugal)
2015/07/04 Targeting dietary hydroxybenzoic acids to mitochondria: A refined strategy to improve Nature V Meeting of the Paul Ehrlich MedChem Euro-PhD Network
Collegium Medicum of Jagiellonian University (Cracóvia, Polónia)
2015/07/04 Targeting dietary hydroxybenzoic acids to mitochondria: A refined strategy to improve Nature Meeting of the Paul Ehrlich MedChem Euro-PhD Network
(Cracóvia, Polónia)
2015/07/02 Antioxidants: from Nature to drug prototypes International Workshop on Biochemistry, Physiology and Pharmacology of Oxidative Stress
Sapienza Università di Roma (Roma, Itália)
2014/06/05 MitoCINs – The highway to target bioactive cinnamic molecules to mitochondria 8th World Congress on Polyphenols Applications
International Society of Antioxidants in Nutrition and Health (Lisboa, Portugal)
2013/09/28 Makeup of natural antioxidants: Design and development of smart carriers to deliver dietary phenolic acids to mitochondria 3rd Meeting of the Paul Ehrlich MedChem Euro-PhD Network
Università di Cagliari (Cagliari, Itália)
2013/09/06 Targeted Delivery of MitoCIN’S: a New Therapeutic Approach for Oxidative Stress Related Diseases 10º Portuguese National Meeting of Organic Chemistry – 1st Portuguese–Brazilian Organic Chemistry Symposium
Sociedade Portuguesa de Química (Lisboa, Portugal)
2013/09/04 Remaking of Dietary Antioxidants: Targeting MitoBEN’s to Mitochondria as a New Therapeutic Strategy 10º Portuguese National Meeting of Organic Chemistry – 1st Portuguese–Brazilian Organic Chemistry Symposium
Sociedade Portuguesa de Química (Lisboa, Portugal)
2013/04/19 Development of novel systems to delivery natural antioxidants to mitochondria: MitoCIN’s as a case study 47th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
European Society for Clinical Investigation (ESCI (Albufeira, Portugal)
2013/02/15 Bridging the gap between nature and antioxidant therapy: development of mitochondria-targeted antioxidants based on benzoic scaffold. IJUP13 - 6º Meeting of young researchers of University of Porto
University of Porto, (Porto, Portugal)
2013/02/14 Mitocondriotropic derivatives based on the natural polyphenol caffeic acid as an way out for oxidative stress related diseases IJUP13 - 6º Meeting of young researchers of University of Porto
University of Porto (Porto, Portugal)
2013/02/13 Development of Smart Carriers For Delivering Menadione to Mitochondria IJUP13 - 6º Meeting of young researchers of University of Porto
University of Porto (Porto, Portugal)
2013/01/09 Development of Smart Carriers for delivering natural antioxidants to Mitochondria 2nd Workshop on Medicinal Chemistry Drug Discovery and Development: Understanding the R&D process
Universidade do Porto (Porto , Portugal)
2012/11/09 Bridging the gap between nature and antioxidant setbacks: Delivering hydroxycinnamic acids to mitochondria TargetingMitochondria 2012
World Mitochondria Society (Berlim, Alemanha)
2012/03/28 Fine-tuning dietary phenolic acids as mitochondriotropic antioxidants: an innovative therapeutic strategy for neurodegenerative disorders V Meeting of Biochemistry at University of Trás-os-Montes e Alto Douro
University of Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2012/02/24 Development of innovative lipophilic hydroxycinnamic antioxidants: a solution to tackle mitochondrial oxidative damage IJUP12 - 5º Meeting of young researchers of University of Porto
University of Porto, (Porto , Portugal)
2011/11/11 Striving for Success in Antioxidant Therapy 10th Indo-Italian Workshop “Chemistry and Biology Antioxidants
Sapienza University (Roma , Itália)
2011/11/10 Fine-tuning the hydrophobicity of natural antioxidants: development of innovative mitochondria-targeted antioxidants based on the cinnamic Scaffold 10th Indo-Italian Workshop on “Chemistry and Biology Antioxidants
Sapienza University (Roma , Itália)
2011/11/10 New solutions for an old problem: surpassing the pharmacokinetic drawbacks of natural phenolic antioxidants 10th Indo-Italian Workshop “Chemistry and Biology Antioxidants
Sapienza University (Roma , Itália)
2011/10/21 Toward the discovery of new Lipophilic antioxidants based on cinnamic acid scaffold as mitochondria-directed neuroprotective agents Targeting Mitochondria 2011 – Strategies, Innovations & Clinical Applications
World Mitochondria Society (Berlim, Alemanha)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022/09/06 - 2026/08/05 Targeting Cardiac Mitochondria with a New Generation of Multi-Purpose Cardioprotective Molecules
Orientador de Caroline Veloso
Biomedicine and Experimental Biology (Doutoramento)
Universidade de Coimbra, Portugal
2023/01/02 - 2025/05/06 O efeito de terapias direcionadas para as mitocôndrias baseadas em antioxidantes da dieta na reprodução assistida
Coorientador de Filipa Nascimento
Tecnologias Agroalimentares (Doutoramento)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/04/04 - 2024/05/06 Effects of NRF2 modulated by ECM stiffness on hepatic cells metabolism and its implications in NAFLD evolution
Coorientador de Heloisa Gerardo
Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra, Portugal
2023/09/15 - 2024/03/26 Impact of impaired peroxisomal fatty acid oxidation on mitochondrial metabolism under fatty acid-induced lipotoxicity insults.
Orientador de Pierluca Cancellieri
Rijksuniversiteit Groningen, Países Baixos
2023/09/01 - 2024/02/27 AVALIAÇÃO DO PERFIL INFLAMATÓRIO E ATIVIDADE MITOCONDRIAL EM UMA POPULAÇÃO OBESA PRÉ E APÓS CIRURGIA BARIÁTRICA
Coorientador
Universidade Federal de Ciências da Saúde de Porto Alegre, Brasil
2022/11/01 - 2023/05/31 A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidants Delivered to Mitochondria
Orientador de Carina Magalhães
Universidade de Coimbra, Portugal
2022/06/01 - 2023/05/31 Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Medicinal Plants from Côa Valley
Coorientador de Ricardo Amorim
Universidade de Coimbra, Portugal
2023/02/03 - 2023/05/25 Effects of NRF2 modulated by ECM stiffness on hepatic cells metabolism and its implications in NAFLD evolution
Orientador de Ana Tavares
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra, Portugal
2022/07/05 - 2022/12/20 Evaluation of piperine derived mitochondria-targeted drugs on breast cancer cells
Coorientador de Mariam Muradova
Nacional'nyj issledovatel'skij universitet ITMO, Rússia
2022/07/05 - 2022/12/20 Evaluation of piperine derived mitochondria-targeted drugs on breast cancer cells
Coorientador de Alena Proskura
Nacional'nyj issledovatel'skij universitet ITMO, Rússia
2022/09/01 - 2022/10/04 Improvig Nature by Addressing Bioactive Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease
Orientador de Rafael Silveira
Universidade de Coimbra, Portugal
2022/02/01 - 2022/08/30 Improvig Nature by Addressing Bioactive Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease
Orientador de Ivana Djedovic
Sveucili¿ta Josipa Jurja Strossmayera u Osijeku, Croácia
2022/03/01 - 2022/08/02 Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Medicinal Plants from Côa Valley
Coorientador de Victoria Ilina
Nacional'nyj issledovatel'skij universitet ITMO, Rússia
2022/03/01 - 2022/06/02 Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Medicinal Plants from Côa Valley
Coorientador de Beatriz Neves
Universidade de Coimbra, Portugal
2022/01/03 - 2022/05/11 Avaliação dos efeitos da modelação da via das pentoses fosfatos na proliferação de células cancerígenas hepáticas.
Coorientador de João Patricio
Bioquímica (Mestrado)
Universidade de Coimbra, Portugal
2022/02/01 - 2022/03/15 Efeitos do antioxidante mitocondriótropico AntiOxCIN4 no metabolismo hepático num modelo animal de esclerose lateral amiotrófica (ELA).
Coorientador de MARIA MANUELA MARTINS SILVÉRIO PEREIRA JORGE
 Mestre em Medicina Veterinária (Licenciatura/Bacharelato)
Escola Universitária Vasco da Gama, Portugal
2017/09/08 - 2021/08/10 Antioxidant targeting of mitochondria to prevent non-alcoholic fatty liver disease-induced oxidative stress and inflammation
Coorientador de Ricardo Fernando Santos Amorim
 Biomedicina e Biologia Experimental (Doutoramento)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/09/07 - 2019/09/04 MITOCHONDRIOTROPIC ANTIOXIDANTS BASED ON DIETARY PHENOLIC ACIDS AS MODULATORS OF OXIDATIVE STRESS ON SKIN FIBROBLASTS
Coorientador de Caroline Delgado Veloso
Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09/05 - 2019/09/04 Targeting Dietary Antioxidants to Mitochondria to Modulate Redox Signaling and Metabolism of Human Fibroblasts
Orientador de André Filipe dos Santos Barbosa
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/03/04 - 2019/06/06 Non-Alcoholic Fatty Liver Disease (NAFLD): The Role of p66shc in the Disease Progression
Orientador de Vincenzo Piedimonte
 Biologia (Licenciatura/Bacharelato)
Università degli Studi del Sannio, Itália
2019/02/01 - 2019/03/02 Avaliação da zonulina plasmática como potencial biomarcador de patologia inflamatória em Felídeos
Coorientador de Márcia Filipa Marques Aleixo
 Medicina Veterinária (Licenciatura/Bacharelato)
Escola Universitária Vasco da Gama, Portugal
2013/01/03 - 2019/02/04 Nanotecnhology breakthrough: penetration of the blood-brain barrier for the treatment of neurodegenerative diseases
Coorientador de Carlos Eduardo Vinhas Fernandes
 Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/09/06 - 2019/01/07 EVALUATION OF ANTIOXIDANT EFFECTS OF MITOCHONDRIA-TARGETED POLYPHENOLIC AGENTS IN HUMAN SKIN FIBROBLASTS
Orientador de Rodrigo Barreto Carreira
 Biologia (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/01/03 - 2018/12/21 Development of bifunctional agents for ameliorating the oxidative stress associated with aging related diseases
Coorientador de Ester Sofia Teixeira Benfeito
Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/09/04 - 2017/09/09 Edible mushrooms as mediators of sustainability and human health
Coorientador de Cátia de Fátima Pires Gomes
Biodiversidade e Biotecnologia Vegetal (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/02/01 - 2017/07/26 Development and Validation of Mitochondrionotropic Molecules
Orientador de João Pedro Gomes de Oliveira Braz
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/09/02 - 2015/07/06 Mitochondria-directed Antioxidants as Anticancer Agents
Coorientador de Katia Queirós Fernandes dos Santos
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/01/05 - 2013/06/04 Desenvolvimento de agentes mitocondriotrópicos: estratégia terapêutica inovadora para doenças neurodegenerativas
Coorientador de Ricardo Fernando Santos Amorim
 Bioquímica (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/02/01 - 2023/12/02 Mitochondria in Aging, Cancer and Cell Death – MAC2023 meeting https://sites.google.com/view/mac2023/ (2023/11/30 - 2023/12/02)
Congresso (Membro da Comissão Organizadora)
 Universidade de Coimbra, Portugal
2019/04/27 - 2019/06/01 Annual course “Mitochondra and Disease” at the Institute for Education and Citizenship (IEC, Cantanhede, Portugal). (2019/04/27)
Seminário (Coorganizador)
 Instituto de Educação e Cidadania , Portugal
2019/05/22 - 2019/05/24 53th Annual Scientific Meeting of the European Society for Clinical Investigation (2019/05/22 - 2019/05/24)
Congresso (Membro da Comissão Científica)
 European Society for Clinical Investigation, Países Baixos
2017/04/22 - 2017/06/03 Annual course “Mitochondra and Disease” at the Institute for Education and Citizenship (IEC, Cantanhede, Portugal). (2017/04/22)
Seminário (Coorganizador)
 Instituto de Educação e Cidadania , Portugal
2016/04/02 - 2016/05/21 Annual course “Mitochondra and Disease” at the Institute for Education and Citizenship (IEC, Cantanhede, Portugal). (2016/04/02)
Seminário (Coorganizador)
 Instituto de Educação e Cidadania , Portugal
2013/04/17 - 2013/04/20 47th Annual Scientific Meeting of the European Society for Clinical Investigation (2013/04/17 - 2013/04/20)
Congresso (Membro da Comissão Organizadora)
 European Society for Clinical Investigation, Países Baixos
2009/09/13 - 2009/09/17 Hyceltec 2009 – II Iberian Symposium on Hydrogen, Fuel Cells and Advanced Batteries (2009/09/13 - 2009/09/17)
Congresso (Membro da Comissão Organizadora)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2008/08/03 - 2008/08/05 11 th International Symposium on Polymer Electrolytes. (2008/08/03 - 2008/08/05)
Congresso (Membro da Comissão Organizadora)
 Universidade de Trás-os-Montes e Alto Douro, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022/05/20 - Atual Semana Internacional do Cérebro: Feira do Cérebro, Jardim Botânico da Universidade de Coimbra
Exposição
 Semana Internacional do Cérebro: Feira do Cérebro
Universidade de Coimbra, Portugal
2017/09/26 - Atual Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/09/29 - Atual Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/09/30 - Atual Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/09/26 - Atual Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/09/04 - Atual "Pergunta-me Ciência" activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 "Pergunta-me Ciência"
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/09/28 - Atual Noite Europeia dos Investigadores activities at the Center for Neuroscience and Cell Biology
Oficina (workshop)
 Noite Europeia dos Investigadores
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/09/19 - 2019/10/10 Programa de Imersão BfK ideas 2019
Concurso
 Programa de Imersão BfK Ideas 2019,
Bfk - Born from Knowledge, Portugal
2019/03/22 - 2019/03/22 Brain Awareness Week 2019 (BAW 2019), Agrupamento de Escolas da Mealhada, Pampilhosa, Mealhada.
Exposição
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/07/13 - 2018/07/13 MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium
Simpósio
 MitoPorto: Mitochondrial Evolution, Metabolism and Disease International Symposium
Universidade do Porto Faculdade de Farmácia, Portugal
2017/05/26 - 2017/05/26 MitoPorto: Advances in Mitochondrial Research International Symposium
Simpósio
 MitoPorto: Advances in Mitochondrial Research International Symposium
Universidade do Porto Faculdade de Farmácia, Portugal
2016/03/01 - 2016/06/01 COHiTEC – Turning Science into Business
Concurso
 COHiTEC – Turning Science into Business
COTEC Portugal/Porto Business School, Portugal
2012/03/02 - 2012/03/02 Cromatografia Liquida
Exposição
 Cromatografia Liquida
Dias de Sousa Instrumentação Analitica e Cientifica, S.A, Portugal
2011/12/06 - 2011/12/06 XIII Encontro Gesventure
Encontro
 XIII Encontro Gesventure
Gesventure, Banco Popular, FNABA – Federação Nacional de Associações de Business Angels e Gesbanha, Gestão e Contabilidade, S.A, Portugal
2009/05/05 - 2009/05/08 Mitochondria: Between Life and Death, International Courses on Toxicology
Oficina (workshop)
 Mitochondria: Between Life and Death, International Courses on Toxicology
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2022/12/06 TARGETED MOLECULES TO ASSESS AND IMPROVE HUMAN SPERM QUALITY A MITOCHONDRIAL PERSPECTIVE
Arguente
 Sara de Jesus Gomes Escada Rebelo (Doutoramento)
Universidade de Coimbra, Portugal
2020/01/17 Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders
Arguente
 Daniel Freitas Chavarria (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09/06 Targeting Dietary Antioxidants to Mitochondria to Modulate Redox Signaling and Metabolism of Human Fibroblasts
Orientador
 André Filipe dos Santos Barbosa (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/01/07 EVALUATION OF ANTIOXIDANT EFFECTS OF MITOCHONDRIA-TARGETED POLYPHENOLIC AGENTS IN HUMAN SKIN FIBROBLASTS
Orientador
 Rodrigo Barreto Carreira (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09/04 Edible mushrooms as mediators of sustainability and human health
Arguente principal
 Cátia de Fátima Pires Gomes (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023/04/10 - 2023/04/15 Laboratorial classes of Doctoral Course “Metodologias para medir o consumo de oxigénio mitocondria” for the BEB Doctoral Program 2023 (University of Coimbra). Total time of course: 18h. Biologia Experimental e Biomedicina (Doutoramento) Universidade de Coimbra, Portugal
2023/03/13 - 2023/03/14 Lecturing in Classes of “Cancer Molecular Biology” for the Master Programme in Biochemistry and Cellular and Molecular Biology (Department of Zoology/Life Sciences, University of Coimbra, Portugal). Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra, Portugal
2022/03/18 - 2022/03/18 Laboratorial classes of “Cancer Molecular Biology” for the Master Programme in Biochemistry and Cellular and Molecular Biology (Department of Zoology/Life Sciences, University of Coimbra, Portugal). Biologia Celular e Molecular (Mestrado integrado) Universidade de Coimbra, Portugal
2019/10/15 - 2019/10/17 Laboratorial classes of “Metabolism” for the Master Programme in Biochemistry (Department of Zoology/Life Sciences, University of Coimbra, Portugal) with the following topics: “Development of a new generation of mitochondria-targeted antioxidants: the importance of molecules from natural origin”. Mestrado em Bioquímica (Mestrado) Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/04/27 - 2019/06/01 Participation as docent in Experimental Advanced Courses for Students and Teachers of Highschool. In the area of Biomedicine: Mitochondria and Diseases – Mitochondria as a toxicological tool: Mitochondria toxicity of polluants and new chemical entities in drug discovery processes. Biomedicine: Mitochondria and Diseases (Ensino secundário) Instituto de Educação e Cidadania , Portugal
2017/04/22 - 2017/06/03 Participation as docent in Experimental Advanced Courses for Students and Teachers of Highschool. In the area of Biomedicine: Mitochondria and Diseases – Mitochondria as a toxicological tool: Mitochondria toxicity of polluants and new chemical entities in drug discovery processes. Biomedicine: Mitochondria and Diseases (Ensino secundário) Instituto de Educação e Cidadania , Portugal
2017/05/15 - 2017/05/16 Lecturing "Toxicology vs Pharmacology" inserted in the “Sub-30” science communication activity, Exploratório – Ciência Viva, Coimbra, Portugal. Duration of 3 hours, held in Escola Secundária de Vila Nova de Poiares, Vila Nova de Poiares, Portugal. Toxicology vs Pharmacology (Ensino secundário) Ciência Viva, Portugal
2017/03/06 - 2017/03/10 Lecturing of Doctoral Course "Metabolism and Disease: Causes and Consequences of Non-Alcoholic Fatty Liver Disease (NAFLD)" BEB Doctoral Program 2017 (University of Coimbra). Total time of course: 40h. Metabolism and Disease: Causes and Consequences of Non-Alcoholic Fatty Liver Disease (NAFLD) (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/04/02 - 2016/05/21 Participation as docent in Experimental Advanced Courses for Students and Teachers of Highschool. In the area of Biomedicine: Mitochondria and Diseases – Mitochondria as a toxicological tool: Mitochondria toxicity of polluants and new chemical entities in drug discovery processes. Biomedicine: Mitochondria and Diseases (Ensino secundário) Instituto de Educação e Cidadania , Portugal

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2021/05/02 - 2026/08/29 Ph.D. Thesis Preliminary Exam Examining Committee
Membro
 Universidade de Coimbra, Portugal

Revisão ad hoc de artigos em revista

Nome da revista (ISSN) Editora
2022/09/02 - Atual International Journal of Biochemistry and Cell Biology
2022/04/30 - Atual Frontiers in Endocrinology
2022/02/05 - Atual Free Radicals Biology and Medicine
2022/01/02 - Atual International Journal of Molecular Science
2019/04/05 - Atual European Journal for Clinical Investigation
Distinções

Prémio

2020 Stimulus of Scientific Employment, Individual Support (CEECIND) - 3rd Edition
Fundação para a Ciência e a Tecnologia, Portugal
2018 ESCI 2018 Poster Award from ESCI 2018
European Society for Clinical Investigation, Países Baixos
2017 ITC Conference Grant from COST
European Cooperation in Science & Technology , Áustria
2016 Student travel grant from ESCI 2016
European Society for Clinical Investigation, Países Baixos
2016 Award of Excellence from Paul Ehrlich MedChem Euro-PhD Network
Paul Ehrlich MedChem Euro-PhD Network , Hungria
2015 Student travel grant from ESCI 2015
European Society for Clinical Investigation, Países Baixos
2015 ESCI 2015 Poster Award (co-author) from ESCI 2015
European Society for Clinical Investigation, Países Baixos
2012 Young Investigator Scholarship grant from ADDF 2012
Alzheimer’s Drug Discovery Foundation, Estados Unidos

Outra distinção

2011 Doctoral scholarship
Fundação para a Ciência e a Tecnologia, Portugal