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Sandra Barata Antunes completed her MSc in Biomedical Science from the University of Beira Interior in 2016. Her MSc work consisted in the study of the role of histamine on the modulation of hippocampal inflammation and neurogenesis in adult mice, which resulted in 2 co-authored papers published in international peer-reviewed journals. Currently, she is a phD student (PhD programme in Applied Health Sciences) at Life and Health Sciences Research Institute (ICVS, School of Medicine, University of Minho) under the supervision of António Salgado. Her current research work is focused on the development of nanosystems for the delivery of cellular secretome in the context of Parkinson's Disease.
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Identificação

Identificação pessoal

Nome completo
Sandra Raquel Pinto Barata Antunes

Nomes de citação

  • Barata-Antunes, Sandra

Identificadores de autor

Ciência ID
1A14-97A3-7FAB
ORCID iD
0000-0003-1858-4318

Telefones

Telemóvel
  • 917948879 (Pessoal)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências da Engenharia e Tecnologias - Nanotecnologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2017/11 - 2021/11
Em curso
 PhD student in FCT PhD programme in Applied Health Sciences (School of Medicine) (Doutoramento)
Universidade do Minho, Portugal
2014/09 - 2016/11
Concluído
 MSc in Biomedical Science (Mestrado)
Universidade da Beira Interior, Portugal
"Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of inflammation and neurogenesis in the hippocampus" (TESE/DISSERTAÇÃO)
 17
2011/09 - 2014/07
Concluído
 BSc in Biomedical Sciences (Licenciatura)
Universidade da Beira Interior, Portugal
 14
2008/09 - 2011/07
Concluído
 Scientific-Humanistic Course of Science and Technology (Ensino secundário)
Didáxis Cooperativa de Ensino, Portugal
 18
Percurso profissional

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/09 - Atual PhD student Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho , Portugal
ICVS/3B’s – PT Government Associate Laboratory, Portugal
Projetos

Projeto

Designação Financiadores
2018/07/01 - 2021/12/31 Combinação do Secretoma de Células Estaminais Mesenquimatosas MSCs e terapias farmacológicas para o tratamento da Doença de Parkinson
PTDC/MED-FAR/29751/2017
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em revista
  1. Mendes-Pinheiro, Bárbara; Campos, Jonas; Marote, Ana; Soares-Cunha, Carina; Nickels, Sarah L.; Monzel, Anna S.; Cibrão, Jorge R.; et al. "Treating Parkinson¿'isease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration". Cells 12 21 (2023): 2565. http://dx.doi.org/10.3390/cells12212565.
    10.3390/cells12212565
  2. Araújo, Bruna; Campos, Jonas; Caridade-Silva, Rita; Mendes-Pinheiro, Bárbara; Marques, Raquel; Barata, Sandra; Lima, Rui; et al. "MODULATION OF BRAIN CONNECTIVITY, STRUCTURE, NEURON AND GLIA, AND MOTOR FUNCTION BY SAFINAMIDE MULTIMODAL ACTIONS IN A PRE-CLINICAL MODEL OF PARKINSON’S DISEASE". IBRO Neuroscience Reports 15 (2023): S212. http://dx.doi.org/10.1016/j.ibneur.2023.08.337.
    10.1016/j.ibneur.2023.08.337
  3. Deolinda Silva; Lucas Schirmer; Tiffany S. Pinho; Passant Atallah; Jorge R. Cibrão; Rui Lima; João Afonso; et al. "Sustained Release of Human Adipose Tissue Stem Cell Secretome from Star-Shaped Poly(ethylene glycol) Glycosaminoglycan Hydrogels Promotes Motor Improvements after Complete Transection in Spinal Cord Injury Rat Model". Advanced Healthcare Materials (2023): https://doi.org/10.1002/adhm.202202803.
    10.1002/adhm.202202803
  4. Bárbara Mendes-Pinheiro; Carina Soares-Cunha; Ana Marote; Eduardo Loureiro-Campos; Jonas Campos; Sandra Barata-Antunes; Daniela Monteiro-Fernandes; et al. "Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response". International Journal of Molecular Sciences 22 21 (2021): 11530-11530. https://doi.org/10.3390/ijms222111530.
    10.3390/ijms222111530
  5. Sandra Barata-Antunes; Fábio G. Teixeira; Bárbara Mendes-Pinheiro; Ana V. Domingues; Helena Vilaça-Faria; Ana Marote; Deolinda Silva; Rui A. Sousa; António J. Salgado. "Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease". International Journal of Molecular Sciences 21 10 (2020): 3459-3459. https://doi.org/10.3390/ijms21103459.
    10.3390/ijms21103459
  6. Antunes, Sandra. "Cell and Tissue Instructive Materials for Central Nervous System Repair". Advanced Functional Materials (2020): http://dx.doi.org/10.1002/adfm.201909083.
    10.1002/adfm.201909083
  7. Antunes, Sandra. "Histamine modulates hippocampal inflammation and neurogenesis in adult mice". Scientific Reports (2019): http://dx.doi.org/10.1038/s41598-019-44816-w.
    10.1038/s41598-019-44816-w
  8. Antunes, Sandra. "Dual role of histamine on microglia-induced neurodegeneration". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2017): http://dx.doi.org/10.1016/j.bbadis.2016.12.016.
    10.1016/j.bbadis.2016.12.016
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/06/28 Podium presentation about "Developing brain-targeting liposomes to deliver mesenchymal stem cells secretome for Parkinson's Disease Regenerative Medicine" TERMIS European Chapter Conference 2022
Tissue Engineering and Regenerative Medicine International Society (TERMIS) (Kraków, Polónia)
2021/12/02 Poster communication about "Developing ligand-functionalized liposomes to deliver mesenchymal stem cells secretome for Parkinson’s Disease Regenerative Medicine" on the XVII Meeting of the Portuguese Society for Neuroscience, Coimbra, Portugal XVII Meeting of the Portuguese Society for Neuroscience
Portuguese Society for Neuroscience (Coimbra, Portugal)
2021/11/15 Poster communication about "Developing lipid-based nanoparticles for systemic delivery of mesenchymal stem cells secretome in Parkinson's disease Regenerative Medicine" on the 6TH TERMIS WORLD CONGRESS, Maastricht, Netherlands 6TH TERMIS WORLD CONGRESS
Tissue Engineering and Regenerative Medicine International Society (Maastricht, Países Baixos)
2017/05 Poster communication about "Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of inflammation and neurogenesis in the hippocampus" at the I Symposium in Applied Biochemistry, University of Minho (Braga, Portugal) I Symposium in Applied Biochemistry
University of Minho (Braga, Portugal)
2016/06 Oral communication about "Unveiling a novel crosstalk between histamine and lipopolysaccharide in the modulation of inflammation and neurogenesis in the hippocampus” at the XI ANNUAL CICS-UBI SYMPOSIUM 2016, UBI, Covilhã, Portugal. XI ANNUAL CICS-UBI SYMPOSIUM
University of Beira Interior (Covilhã, Portugal)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2018 - 2019/05/22 Participated in organization of the I festival Pint of Science at Braga (Portugal) (2019/05/20 - 2019/05/22)
Festival (Membro da Comissão Organizadora)
2018 - 2018 Participated in organization of the "I international symposium Secretome With]Out[ Borders" at School of Medicine (UM, Braga, Portugal). (2018/12/06 - 2018/12/07)
Simpósio (Membro da Comissão Organizadora)
 Universidade do Minho, Portugal
2015 - 2015 Participated in organization of the "IV Symposium on Employment and Opportunities in Biomedical Sciences" at UBIMedical (Covilhã, Portugal) (2015/05/27 - 2015/05/27)
Simpósio (Membro da Comissão Organizadora)
 UBIMedical , Portugal
2013 - 2014 Participated in organization of the "V National Conferences of Biomedical Sciences" at FCS (UBI, Covilhã, Portugal). (2014/03/13 - 2014/03/15)
Congresso (Membro da Comissão Organizadora)
 Universidade da Beira Interior, Portugal
2012 - 2013 Participated in organization of the "I Cycle of Biomedical Afternoon Conferences" at FCS (UBI, Covilhã, Portugal) (2013 - 2013)
Conferência (Membro da Comissão Organizadora)

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/10/10 - 2019/10/12 Attended the "11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)", Faculty of Pharmacy, Lisbon, Portugal.
Encontro
 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Membro de associação

Nome da associação Tipo de participação
2012 - 2015 Biomedical Sciences Students' Association (UBI, Covilhã, Portugal) - Responsible for the Marketing and Communication Department Responsible for the Marketing and Communication Department

Tutoria

Tópico Nome do aluno
2022/05/01 - 2022/06/27 Co-Supervisor of a graduation laboratory internship entitled "Efeito do secretoma de Células Estaminais Mesenquimatosas encapsulado em lipossomas funcionalizados - Análise motora e histológica num modelo animal da Doença de Parkinson" Ana Teresa Palha Sousa
2021/12/01 - 2022/01/15 Co-Supervisor of a laboratory rotation entitled "New approaches for stem-cell secretome encapsulation using lipid-based systems" Rúben Luís Silva
Distinções

Prémio

2017 Best poster communication in "I Symposium in Applied Biochemistry" at University of Minho
Universidade do Minho, Portugal