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Senior Group Leader: Polarity Division Morphogenesis team, Genetics and Developmental Biology Unit, CNRS U3215 INSERM U934 Curie Institute, Paris (France).
Identificação

Identificação pessoal

Nome completo
BELLAICHE Yohanns

Nomes de citação

  • BELLAICHE, Yohanns

Identificadores de autor

Ciência ID
1911-BBC1-6E9D
ORCID iD
0000-0003-1686-2943

Websites

  • https://science.institut-curie.org/research/biology-cancer-genetics-and-epigenetics/developmental-biology-and-genetics/team-bellaiche/ (Profissional)
Produções

Publicações

Artigo em revista
  1. López-Gay, Jesús M.; Nunley, Hayden; Spencer, Meryl; di Pietro, Florencia; Guirao, Boris; Bosveld, Floris; Markova, Olga; et al. "Apical stress fibers enable a scaling between cell mechanical response and area in epithelial tissue". Science 370 6514 (2020): eabb2169. http://dx.doi.org/10.1126/science.abb2169.
    10.1126/science.abb2169
  2. Yu, Joyce J.S.; Maugarny-Calès, Aude; Pelletier, Stéphane; Alexandre, Cyrille; Bellaiche, Yohanns; Vincent, Jean-Paul; McGough, Ian J.. "Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands". Developmental Cell 54 5 (2020): 583-592.e5. http://dx.doi.org/10.1016/j.devcel.2020.08.004.
    10.1016/j.devcel.2020.08.004
  3. Villedieu, Aurélien; Bosveld, Floris; Bellaïche, Yohanns. "Mechanical induction and competence in epithelial morphogenesis". Current Opinion in Genetics & Development 63 (2020): 36-44. http://dx.doi.org/10.1016/j.gde.2020.03.003.
    10.1016/j.gde.2020.03.003
  4. Bosveld, F; Bellaïche, Y. "Tricellular junctions". Current Biology 30 6 (2020): R249-R251. http://dx.doi.org/10.1016/j.cub.2020.01.029.
    10.1016/j.cub.2020.01.029
  5. van Leen, EV; di Pietro, F; Bellaïche, Y. "Oriented cell divisions in epithelia: from force generation to force anisotropy by tension, shape and vertices". Current Opinion in Cell Biology 62 (2020): 9-16. http://dx.doi.org/10.1016/j.ceb.2019.07.013.
    10.1016/j.ceb.2019.07.013
  6. Edwards-Jorquera, SS; Bosveld, F; Bellaïche, Y; Lennon-Duménil, A-M; Glavic, Á. "Trpml controls actomyosin contractility and couples migration to phagocytosis in fly macrophages". The Journal of Cell Biology 219 3 (2020): http://dx.doi.org/10.1083/jcb.201905228.
    10.1083/jcb.201905228
  7. Goshima, G; Bellaïche, Y. "Editorial overview: Cell division – from molecules to tissues". Current Opinion in Cell Biology 60 (2019): iii-v. http://dx.doi.org/10.1016/j.ceb.2019.06.006.
    10.1016/j.ceb.2019.06.006
  8. Krndija, D; El Marjou, F; Guirao, B; Richon, S; Leroy, O; Bellaiche, Y; Hannezo, E; Matic Vignjevic, D. "Active cell migration is critical for steady-state epithelial turnover in the gut". Science 365 6454 (2019): 705-710. http://dx.doi.org/10.1126/science.aau3429.
    10.1126/science.aau3429
  9. Edwards, SS; Delgado, MG; Nader, GPF; Piel, M; Bellaiche, Y; Lennon-Duménil, A-M; Glavic, Á. "An in vitro method for studying subcellular rearrangements during cell polarization in Drosophila melanogaster hemocytes". Mechanisms of Development 154 (2018): 277-286. http://dx.doi.org/10.1016/j.mod.2018.08.003.
    10.1016/j.mod.2018.08.003
  10. Pinheiro, D; Bellaïche, Y. "Mechanical Force-Driven Adherens Junction Remodeling and Epithelial Dynamics". Developmental Cell 47 1 (2018): 3-19. http://dx.doi.org/10.1016/j.devcel.2018.09.014.
    10.1016/j.devcel.2018.09.014
  11. Bosveld, F; Wang, Z; Bellaïche, Y. "Tricellular junctions: a hot corner of epithelial biology". Current Opinion in Cell Biology 54 (2018): 80-88. http://dx.doi.org/10.1016/j.ceb.2018.05.002.
    10.1016/j.ceb.2018.05.002
  12. di Pietro, F; Bellaïche, Y. "Actin Network Discussion during Mitotic Pseudo-Furrowing". Developmental Cell 45 5 (2018): 539-541. http://dx.doi.org/10.1016/j.devcel.2018.05.018.
    10.1016/j.devcel.2018.05.018
  13. Wang, Z; Bosveld, F; Bellaïche, Y. "Tricellular junction proteins promote disentanglement of daughter and neighbour cells during epithelial cytokinesis". Journal of Cell Science 131 11 (2018): jcs215764. http://dx.doi.org/10.1242/jcs.215764.
    10.1242/jcs.215764
  14. Guirao, B; Bellaïche, Y. "Biomechanics of cell rearrangements in Drosophila". Current Opinion in Cell Biology 48 (2017): 113-124. http://dx.doi.org/10.1016/j.ceb.2017.06.004.
    10.1016/j.ceb.2017.06.004
  15. Bosveld, F; Ainslie, A; Bellaïche, Y. "Sequential activities of Dynein, Mud and Asp in centrosome–spindle coupling maintain centrosome number upon mitosis". Journal of Cell Science 130 20 (2017): 3557-3567. http://dx.doi.org/10.1242/jcs.201350.
    10.1242/jcs.201350
  16. Tissot, N; Lepesant, J-A; Bernard, F; Legent, K; Bosveld, F; Martin, C; Faklaris, O; et al. "Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocyte". Nature Communications 8 1 (2017): http://dx.doi.org/10.1038/ncomms15168.
    10.1038/ncomms15168
  17. Pinheiro, D; Hannezo, E; Herszterg, S; Bosveld, F; Gaugue, I; Balakireva, M; Wang, Z; et al. "Transmission of cytokinesis forces via E-cadherin dilution and actomyosin flows". Nature 545 7652 (2017): 103-107. http://dx.doi.org/10.1038/nature22041.
    10.1038/nature22041
  18. Park, S; Gonzalez, D; Guirao, B; Boucher, JD; Cockburn, K; Marsh, ED; Mesa, KR; et al. "Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice". Nature Cell Biology 19 3 (2017): 155-163. http://dx.doi.org/10.1038/ncb3472.
    10.1038/ncb3472
  19. Bellaïche, Y. "Cell Division in the Light of Modeling". Developmental Cell 38 6 (2016): 584-586. http://dx.doi.org/10.1016/j.devcel.2016.09.008.
    10.1016/j.devcel.2016.09.008
  20. Bosveld F; Markova O; Guirao B; Martin C; Wang Z; Pierre A; Balakireva M; et al. "Erratum: Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis.". (2016): http://europepmc.org/abstract/med/26982720.
    10.1038/nature17622
  21. Bosveld F; Markova O; Guirao B; Martin C; Wang Z; Pierre A; Balakireva M; et al. "Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis.". (2016): http://europepmc.org/abstract/med/26886796.
    10.1038/nature16970
  22. Bosveld F; Guirao B; Wang Z; Rivière M; Bonnet I; Graner F; Bellaïche Y. "Modulation of junction tension by tumor suppressors and proto-oncogenes regulates cell-cell contacts.". (2016): http://europepmc.org/abstract/med/26811379.
    10.1242/dev.127993
  23. Martín-Bermudo MD; Bardet PL; Bellaïche Y; Malartre M. "The vav oncogene antagonises EGFR signalling and regulates adherens junction dynamics during Drosophila eye development.". (2015): http://europepmc.org/abstract/med/25813543.
    10.1242/dev.110585
  24. Guirao B; Rigaud SU; Bosveld F; Bailles A; López-Gay J; Ishihara S; Sugimura K; Graner F; Bellaïche Y. "Unified quantitative characterization of epithelial tissue development.". (2015): http://europepmc.org/abstract/med/26653285.
    10.7554/eLife.08519
  25. Herszterg S; Pinheiro D; Bellaïche Y. "A multicellular view of cytokinesis in epithelial tissue.". (2014): http://europepmc.org/abstract/med/24380642.
    10.1016/j.tcb.2013.11.009
  26. Pinheiro D; Bellaïche Y. "Making the most of the midbody remnant: specification of the dorsal-ventral axis.". (2014): http://europepmc.org/abstract/med/24525182.
    10.1016/j.devcel.2014.01.026
  27. Bouissou A; Vérollet C; de Forges H; Haren L; Bellaïche Y; Perez F; Merdes A; Raynaud-Messina B. "¿-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning.". (2014): http://europepmc.org/abstract/med/24421324.
    10.1002/embj.201385967
  28. Bardet PL; Guirao B; Paoletti C; Serman F; Léopold V; Bosveld F; Goya Y; et al. "PTEN controls junction lengthening and stability during cell rearrangement in epithelial tissue.". (2013): http://europepmc.org/abstract/med/23707736.
    10.1016/j.devcel.2013.04.020
  29. Heisenberg CP; Bellaïche Y. "Forces in tissue morphogenesis and patterning.". (2013): http://europepmc.org/abstract/med/23706734.
    10.1016/j.cell.2013.05.008
  30. Ishihara S; Sugimura K; Cox SJ; Bonnet I; Bellaïche Y; Graner F. "Comparative study of non-invasive force and stress inference methods in tissue.". (2013): http://europepmc.org/abstract/med/23615875.
    10.1140/epje/i2013-13045-8
  31. Sugimura K; Bellaïche Y; Graner F; Marcq P; Ishihara S. "Robustness of force and stress inference in an epithelial tissue.". (2013): http://europepmc.org/abstract/med/24110287.
    10.1109/EMBC.2013.6610100
  32. Bonnet I; Marcq P; Bosveld F; Fetler L; Bellaïche Y; Graner F. "Mechanical state, material properties and continuous description of an epithelial tissue.". (2012): http://europepmc.org/abstract/med/22628216.
    10.1098/rsif.2012.0263
  33. Bosveld F; Bonnet I; Guirao B; Tlili S; Wang Z; Petitalot A; Marchand R; et al. "Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathway.". (2012): http://europepmc.org/abstract/med/22499807.
    10.1126/science.1221071
  34. Morin X; Bellaïche Y. "Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development.". (2011): http://europepmc.org/abstract/med/21763612.
    10.1016/j.devcel.2011.06.012
  35. Bellaïche Y; Bosveld F; Graner F; Mikula K; Remesíková M; Smísek M. "New robust algorithm for tracking cells in videos of Drosophila morphogenesis based on finding an ideal path in segmented spatio-temporal cellular structures.". (2011): http://europepmc.org/abstract/med/22255854.
    10.1109/IEMBS.2011.6091630
  36. Ségalen M; Johnston CA; Martin CA; Dumortier JG; Prehoda KE; David NB; Doe CQ; Bellaïche Y. "The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish.". (2010): http://europepmc.org/abstract/med/21074723.
    10.1016/j.devcel.2010.10.004
  37. Segalen M; Bellaïche Y. "Cell division orientation and planar cell polarity pathways.". (2009): http://europepmc.org/abstract/med/19447051.
    10.1016/j.semcdb.2009.03.018
  38. Bellaïche Y; Munro E. "Pushing the frontiers of development.". (2009): http://europepmc.org/abstract/med/19103801.
    10.1242/dev.028407
  39. Leibfried A; Bellaïche Y. "Functions of endosomal trafficking in Drosophila epithelial cells.". (2007): http://europepmc.org/abstract/med/17651956.
    10.1016/j.ceb.2007.06.004
  40. Ségalen M; David N; Bellaïche Y. "[The heterotrimeric G proteins during asymmetric cell division in Drosophila].". (2006): http://europepmc.org/abstract/med/16527201.
    10.1051/medsci/2006223243
  41. David NB; Martin CA; Segalen M; Rosenfeld F; Schweisguth F; Bellaïche Y. "Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division.". (2005): http://europepmc.org/abstract/med/16228010.
    10.1038/ncb1319
  42. Langevin J; Morgan MJ; Sibarita JB; Aresta S; Murthy M; Schwarz T; Camonis J; Bellaïche Y. "Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane.". (2005): http://europepmc.org/abstract/med/16224820.
    10.1016/j.devcel.2005.07.013
  43. Langevin J; Le Borgne R; Rosenfeld F; Gho M; Schweisguth F; Bellaïche Y. "Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells.". (2005): http://europepmc.org/abstract/med/15916953.
    10.1016/j.cub.2005.04.054
  44. Orgogozo V; Schweisguth F; Bellaïche Y. "Slit-Robo signalling prevents sensory cells from crossing the midline in Drosophila.". (2004): http://europepmc.org/abstract/med/15147761.
    10.1016/j.mod.2004.04.001
  45. Bellaïche Y; Beaudoin-Massiani O; Stuttem I; Schweisguth F. "The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila.". (2004): http://europepmc.org/abstract/med/14701683.
    10.1242/dev.00928
  46. Orgogozo V; Schweisguth F; Bellaïche Y. "Binary cell death decision regulated by unequal partitioning of Numb at mitosis.". (2002): http://europepmc.org/abstract/med/12361960.
  47. Le Borgne R; Bellaïche Y; Schweisguth F. "Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage.". (2002): http://europepmc.org/abstract/med/11818059.
    10.1016/S0960-9822(01)00648-0
  48. Bellaïche Y; Schweisguth F. "Lineage diversity in the Drosophila nervous system.". (2001): http://europepmc.org/abstract/med/11448628.
    10.1016/S0959-437X(00)00212-4
  49. Bellaïche Y; Radovic A; Woods DF; Hough CD; Parmentier ML; O'Kane CJ; Bryant PJ; Schweisguth F. "The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila.". (2001): http://europepmc.org/abstract/med/11509184.
    10.1016/S0092-8674(01)00444-5
  50. Orgogozo V; Schweisguth F; Bellaïche Y. "Lineage, cell polarity and inscuteable function in the peripheral nervous system of the Drosophila embryo.". (2001): http://europepmc.org/abstract/med/11171389.
  51. Bellaïche Y; Gho M; Kaltschmidt JA; Brand AH; Schweisguth F. "Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division.". (2001): http://europepmc.org/abstract/med/11146626.
    10.1038/35050558
  52. Gho M; Bellaïche Y; Schweisguth F. "Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell.". (1999): http://europepmc.org/abstract/med/10409503.
  53. Bellaïche Y; Bandyopadhyay R; Desplan C; Dostatni N. "Neither the homeodomain nor the activation domain of Bicoid is specifically required for its down-regulation by the Torso receptor tyrosine kinase cascade.". (1996): http://europepmc.org/abstract/med/8951065.