Alexandre Neto is currently a PhD student at the CNS, Blood, and Peripheral Inflammation Lab, headed by Professor Adelaide Fernandes, based on iMed.ULisboa - Faculty of Pharmacy, University of Lisbon. Alexandre's research journey began with a profound interest in Multiple Sclerosis (MS) and during his master's studies was able to work on 3 different projects. He started to evaluate the anti-inflammatory properties of blueberry leaves to lessen MS-associated inflammation in a mouse model of MS. Afterwards, in a different project, he used in vitro methods to modulate mechanical cues of oligodendrocytes, one of the main affected cells in MS. In the next year during his master’s thesis, he was focused on exploring how the use of specific nanobodies to neutralize an inflammatory molecule could prevent MS-associated pathogenesis, using ex vivo demyelinating models. After this, Alexandre continued the studies as a Research Fellow in an exploratory project led by Dr. Andreia Barateiro, which was aimed at understanding the role of obesity, a known MS risk factor, in the development of MS. More recently, Alexandre received a FCT PhD Research Fellowship (2024.01222.BD) to study the biological mechanisms underlying MS progression. His ongoing work is based on the generation of brainspheres to replicate the human CNS environment and study MS-like conditions, using induced pluripotent stem cells from people with MS.