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Rui Pereira is currently an PhD student in Sustainable Chemistry at the Faculty of Farmacy from University of Porto with collaboration with the University of Aveiro. He finished his BSc and MSc degrees in Chemistry at the Faculty of Science from University of Porto with final grades of 18 and 19 respectively (in 20). He received several scholar distinctions, such as the award Teresa Fonseca (2018) and the award Prof. Doutor Manuel Ribeiro da Silva (2019). He performed 3 volunteered internships in scientific investigation, published 5 scientific articles in international peer reviewed journals and participated in international conferences with 12 communications. He was a research fellow with a graduate research grant between June and October of 2020. He has background in chemistry with specialization in organic synthesis and medicinal chemistry.
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Identification

Personal identification

Full name
Rui Filipe Jesus Pereira

Citation names

  • Pereira, Rui

Author identifiers

Ciência ID
0217-FED5-BB62
ORCID iD
0000-0003-1459-0905

Email addresses

  • r97pereira@gmail.com (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2021/04/01 - 2025
Ongoing
 Sustainable Chemistry (Doutoramento)
Major in Organic Chemistry; Medicinal Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
"Design and synthesis of novel bis-chalcone and bis-flavone scaffolds for the treatment of inflammatory diseases " (THESIS/DISSERTATION)
2018/09/13 - 2020/12/02
Concluded
 Chemistry (Mestrado)
Major in Organic Chemistry
Universidade do Porto Faculdade de Ciências, Portugal
"Unnatural ß-amino acid derivatives as potential transdermal drug delivery systems" (THESIS/DISSERTATION)
 19
2019/02/03 - 2019/07/31
Concluded
 Produção de aditivos para gasolinas a partir de resíduos florestais e agrículas (Outros)
Major in Heterogeneous Catalysis
Universidade do Porto Faculdade de Ciências, Portugal
 Excelente
2019/07/09 - 2019/07/11
Attended
 Fármacos: como se obtêm, como atuam e porquê (uma perspetiva da Química Farmacêutica Medicinal) (Curso de Especialização Tecnológica)
Major in Medicinal Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
2018/02/03 - 2018/07/31
Concluded
 Nanossistemas baseados em tensioativos derivados da serina como sistemas de veiculação de fármacos (Outros)
Major in Organic Chemistry
Universidade do Porto Faculdade de Ciências, Portugal
 Excelente
2015/09 - 2018/07/31
Concluded
 Chemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Novos tensioativos derivados de serina: Síntese e estudo de interação com membranas lipídicas" (THESIS/DISSERTATION)
 18
2018/06/25 - 2018/06/28
Concluded
 Membrane Biophysics Impact of Lipids on Health, Disease and Therapy (Curso de Especialização Tecnológica)
Major in Applied Physical Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
 19
2017/02/03 - 2017/07/31
Concluded
 Desenvolvimento de uma nova terapia para cancro baseada em bioluminescência marinha (Outros)
Major in Physical Chemistry
Universidade do Porto Faculdade de Ciências, Portugal
2012 - 2015
Concluded
 Química, Ambiente e Qualidade (Ensino secundário)
Colégio Internato dos Carvalhos, Portugal
 18,8
Affiliation

Others

Category
Host institution 		Employer
2020/06/01 - 2020/12/01 Research fellow Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2018/07 - 2018/07 Monitor - Junior University Summer Courses - 2018 edition Universidade do Porto, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
Outputs

Publications

Book chapter
  1. Rocha, Sónia; Sousa, Adelaide; Pereira, Rui; Freitas, Marisa; Fernandes, Eduarda. "Exploring the antidiabetic potential of chalcones through modulation of PTP1B and PPARy". In Chalcones and their Derivatives From Synthesis to Applications, edited by Mohmmad Younus Wani; Salman Ahmad Khan; Hao Shao; Anish Khan. Elsevier, ISBN: 9780443301223, 2025.
    Accepted
Conference paper
  1. Pereira, Rui; Silva, Vera L. M.; Silva, Artur M. S.; Ribeiro, Daniela; Fernandes, Eduarda. "Synthesis and Chemical Reactivity of Novel Polyhydroxylated Bis-Chalcones". 2022.
    10.3390/ecmc2022-13473
Conference poster
  1. Pereira, Rui; Nolasco, Mariela; Vera L. M. Silva; Eduarda Fernandes. Corresponding author: Eduarda Fernandes. "The challenges of direct Claisen-Schmidt condensation with polyhydroxylated subtracts". Paper presented in XXVI Encontro Galego-Portugués de Química, 2024.
  2. Pereira, Rui; Silva, Artur; Vera L. M. Silva. Corresponding author: Vera L. M. Silva. "Bis-Flavones: a novel scaffold for flavonoid chemistry". Paper presented in 29th Congress of the International Society of Heterocyclic Chemistry, 2024.
  3. Pereira, Rui; Ribeiro, Daniela; Vera L. M. Silva; Eduarda Fernandes. "Synthesis and evaluation of novel polyhydroxylated bis-chalcones as potential COX-2 selective inhibitors". Paper presented in 58th International Conference on Medicinal Chemistry, 2024.
  4. Pereira, Rui; Vera L. M. Silva; Silva, Artur; Daniela Ribeiro; Eduarda Fernandes. Corresponding author: Eduarda Fernandes. "Synthesis of new bis-chalcone scaffolds as potential inhibitors of cyclooxygenase II". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022.
  5. Pereira, Rui; Silva, Sandra G.; Dias, Ana Rita; Ferraz, Ricardo; Eaton, Peter; Pinheiro, Marina; Reis, Salette; Cardoso do Vale, M.L.. "Serine-based surfactants: potential drug delivery and antimicrobial agents". Paper presented in XXV Encontro Galego--Portugues de Química, 2019.
Journal article
  1. Pereira, Rui; Ribeiro, Daniela; Silva, Vera L.M.; Fernandes, Eduarda. "Synthetic flavonoid dimers: Synthesis strategies and biological activities". European Journal of Medicinal Chemistry 291 (2025): 117669. https://doi.org/10.1016/j.ejmech.2025.117669.
    10.1016/j.ejmech.2025.117669
  2. Pereira, Rui; Nolasco, Mariela; Vera L. M. Silva; Eduarda Fernandes. Corresponding author: Eduarda Fernandes. "The challenges of direct Claisen–Schmidt condensation in the synthesis of polyhydroxylated bis-chalcones: computational insights". ChemPlusChem (2025):
    Submitted
  3. Pereira, Rui; Freitas, Marisa; Araujo, Alberto; Vera L. M. Silva; Eduarda Fernandes. "Design, synthesis, and evaluation of bis-chalcones and bis-flavones as selective COX-2 inhibitors". (2025):
    Submitted
  4. Pereira, Rui. "Design, synthesis and in vitro and in silico evaluation of new polyhydroxylated bis-chalcones as potential COX-2 selective inhibitors". European Journal of Medicinal Chemistry (2025):
    Submitted
  5. Pereira, Rui; Silva, Artur M.S.; Ribeiro, Daniela; Silva, Vera L.M.; Fernandes, Eduarda. "Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects". European Journal of Medicinal Chemistry 252 (2023): 115280. http://dx.doi.org/10.1016/j.ejmech.2023.115280.
    Open access • 10.1016/j.ejmech.2023.115280
  6. Silva, Sandra G.; Pinheiro, Marina; Pereira, Rui; Dias, Ana Rita; Ferraz, Ricardo; Prudêncio, Cristina; Eaton, Peter J.; et al. "Serine-based surfactants as effective antimicrobial agents against multiresistant bacteria". BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2022): http://hdl.handle.net/10400.22/20583.
    10.1016/j.bbamem.2022.183969
  7. Rui Filipe Jesus Pereira; Sandra G. Silva; Marina Pinheiro; Salette Reis; Luísa do Vale. "Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery". Membranes (2021): https://www.mdpi.com/2077-0375/11/5/343.
    10.3390/membranes11050343
  8. Pinto da Silva, L.; Pereira, R.F.J.; Esteves da Silva, J.C.G.. "Theoretical Analysis of the Effect Provoked by Bromine-Addition on the Thermolysis and Chemiexcitation of a Model Dioxetanone". Journal of Chemistry 2017 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018882353&partnerID=MN8TOARS.
    10.1155/2017/1903981
  9. Pinto Da Silva, L.; Pereira, R.F.J.; Magalhães, C.M.; Esteves Da Silva, J.C.G.. "Mechanistic Insight into Cypridina Bioluminescence with a Combined Experimental and Theoretical Chemiluminescent Approach". Journal of Physical Chemistry B 121 33 (2017): 7862-7871. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028358688&partnerID=MN8TOARS.
    10.1021/acs.jpcb.7b06295
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/12 Synthesis and evaluation of novel polyhydroxylated bis-chalconesas potential COX-2 selective inhibitors The ABC day: Usefulness of dietary bioactive compounds and probiotics in promoting health
2023/11/23 Bis-chalcones: A new scaffold for novel and potent inhibitors of cyclooxygenase 2 XXVII Encontro Luso Galego de Química
Delegação do Porto da SPQ (Porto, Portugal)
2023/10/11 Polyhydroxy bis-chalcones: from synthesis to cyclization into novel flavonoids Webinar LAQV-REQUIMTE - Molecular Synthesis Research Group
LAQV-REQUIMTE
2023/07/25 Synthesis of novel polyhydroxylated bis-chalcones and their cyclodehydrogenation into bisflavones XXVIII Encontro Nacional da SPQ
Sociedade Portuguesa de Química (Aveiro, Portugal)
2022/11/17 Polyhydroxylated bis-chalcones: potential new inhibitors of cyclooxygenase 2 XXVI ENCONTRO GALEGO-PORTUGUÉS DE QUÍMICA.
Colegio Oficial de Químicos de Galicia (Santiago de Compostela, Spain)
2020/02/13 Serine-based surfactants: potential drug delivery and antimicrobial agents IJUP´20 - 13 º Encontro de Jovens Investigadores da Universidade do Porto
Universidade do Porto (Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/07/13 - 2023/07/17 "Pesquisa de novas moléculas com atividade anti-inflamatória", activity carried out under the program Junior University Summer Courses - 2023 edition (2023/07/13 - 2023/07/17)
Other (Co-organisor)
 Universidade do Porto Faculdade de Farmácia, Portugal
Distinctions

Award

2019 School Prize Professor Doutor Manuel Ribeiro da Silva
Universidade do Porto Faculdade de Ciências, Portugal
2018 School Prize Teresa Fonseca
Universidade do Porto Faculdade de Ciências, Portugal
2018 School Prize Doutor Mendonça Monteiro
Universidade do Porto Faculdade de Ciências, Portugal
2017 School Prize Prof. Doutor Fernando Serrão
Universidade do Porto Faculdade de Ciências, Portugal
2015 "Caloiros de Química não pagam propinas"
Sociedade Portuguesa de Química, Portugal