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Carlos M. Gastalho graduated in Pharmaceutical Sciences (MSc, PharmD.) in 2012 from the Faculty of Pharmacy of University of Coimbra. He is a Clinical Research Associate (CRA) Certificated and he is currently a PhD Student FCT Grant at University of Évora. His research activity is based on the development of polymeric nanosystems for drugs entrapment (either hydrophilic also hydrophobic) with biological and pharmacological activity further assessed through preclinical assays in cell culture (human fibroblasts (HDFs), dog breast adenocarcinoma cells (REM-134), human keratinocytes (HPEKs), human breast adenocarcinoma cells (MCF-7). He has also attended at four congresses and Symposia related with his PhD and has presented two poster communications, was author of two abstract publication, co-author of one publication, and co-editor of one book. He participated in the organization of several scientific events. He has also participated, as co-supervisor of High School ERASMUS+ students (total:10) at the Laboratory of Biochemistry (University of Évora, 2021) also one Bachelor Student in Biotechnology field (University of Évora, 2022).
Identification

Personal identification

Full name
Carlos Manuel Lopes Gastalho
Date of birth
1986/03/17
Gender
Male

Citation names

  • GASTALHO, C.
  • Gastalho, C. M.

Author identifiers

Ciência ID
931C-80CB-137A
ORCID iD
0000-0002-4077-9755

Email addresses

  • cgastalho@gmail.com (Personal)
  • d46200@alunos.uevora.pt (Personal)

Telephones

Mobile phone
  • 913002580 (Personal)

Addresses

  • R DA LIBERDADE nº 65 - 1º DT, 3045-198, Coimbra, Coimbra, Portugal (Personal)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Engineering and Technology - Nano-technology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
French Elementary (A2) Intermediate (B1) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2022 - 2025
Ongoing
Doctoral Program at Biochemistry - PhD. (Doutoramento)
Major in Biochemistry
Instituto de Ciências da Terra, Portugal

University of Évora, School of Medical Sciences and Health, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
"Development of chitosan-based pharmaco-active nano-systems for incorporation into dermo-compatible hydrogels for human skin wound healing." (THESIS/DISSERTATION)
2022/04 - 2022/06
Concluded
Study Coordinator (Outros)
Major in Ensaios Clínicos
W4R - W4Research Work for Research, Portugal
Excellent
2022/02/18 - 2022/03/01
Concluded
Clinical Data Entry (Outros)
Major in Clinical Trials
W4R - W4Research Work for Research, Portugal
Excellent
2022 - 2022
Ongoing
Clinical Research Associate (Outros)
W4R - W4Research Work for Research, Portugal
2019/09 - 2019/11
Concluded
Clinical Investigator - 2nd Level (Título de especialista)
Major in Clinical Trials
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
85%
2019/07 - 2019/09
Concluded
Clinical Investigator - 1st Level (Título de especialista)
Major in Clinical Trials
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
86 %
2007 - 2012
Concluded
Integrated Master at Pharmaceutical Sciences - PharmD. (Mestrado integrado)
Major in Pharmaceutical Sciences
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Diabetes mellitus Gestacional" (THESIS/DISSERTATION)
Affiliation

Others

Category
Host institution
Employer
2021 - Current PhD Fellowship REQUIMTE, Portugal
Universidade de Évora, Portugal
2021 - Current PhD Fellowship Universidade de Évora Instituto de Investigação e Formação Avançada, Portugal
2021 - Current PhD Fellowship Institute of Earth Sciences - University of Évora , Portugal
Institute of Earth Sciences - University of Évora , Portugal
Projects

Grant

Designation Funders
2022 - Current Development of chitosan-based pharmaco-active nano-systems for incorporation into dermo-compatible hydrogels for human skin wound healing
2022.09574.BDANA
PhD Student Fellow
University of Évora, School of Medical Sciences and Health, Portugal

REQUIMTE LAQV Porto, Portugal

Instituto de Ciências da Terra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Carreiro, Elisabete P.; GASTALHO, C.; Burke, A.J.; Ernesto, Sofia; Antunes, Célia M.; Costa, A. R.. Corresponding author: Carreiro, Elisabete P.. "Synthesis of Novel 1,2,3-Triazole-Quercetin Hybrids with Potential Antioxidant Activity". Paper presented in ISySyCat2019-International Symposium on Synthesis and Catalysis 2021, 2021.
Journal article
  1. Carlos M. Gastalho; Ana M. Sena; Óscar López; José G. Fernández-Bolaños; Alfonso T. García-Sosa; Florbela Pereira; Célia M. Antunes; et al. "Assessing the Potential of 1,2,3-Triazole-Dihydropyrimidinone Hybrids Against Cholinesterases: In Silico, In Vitro, and In Vivo Studies". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms252011153.
    10.3390/ijms252011153
  2. Carlos M. Gastalho; Célia M. Antunes; Elisabete P. Carreiro; César C. Filho; Alexandre C. Craveiro. "Chitosan- and chitosan-polaxamer 407 based nanoparticles synthesis: green nanotechnology tools for Biomedical applications". FEBS Open Bio (2024): http://dx.doi.org/10.1002/2211-5463.13837.
    10.1002/2211-5463.13837
  3. Elisabete P. Carreiro; Carlos M. Gastalho; Sofia Ernesto; Ana R. Costa; Célia M. Antunes; Anthony J. Burke. "Synthesis and Antiproliferative Activity of Novel Quercetin-1,2,3-Triazole Hybrids using the 1,3-Dipolar Cycloaddition (Click) Reaction". Synthesis (2022): https://doi.org/10.1055/s-0040-1719928.
    10.1055/s-0040-1719928
Activities

Event organisation

Event name
Type of event (Role)
Institution / Organization
2021/10/14 - 2021/10/16 Staff member of the XXI National Congress of Biochemistry "Tunning Biochemistry with Life and Society". - abstracts recieving; admissions handling; speakers reception and guide. (2021/10/14 - 2021/10/16)
Congress (Member of the Organising Committee)
Universidade de Évora, Portugal

Instituto de Ciências da Terra, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2021/10/21 - 2021/10/22 Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogelation occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light and others. These three-dimensional networks consisting of mainly water molecules represent a unique class of materials, with many applications including cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, 3D bioprinting.
Symposium
ChemBioGels 2021: Advances in hydrogels for biomedical applications
Universidade do Minho Centro de Química, Portugal

Fundação para a Ciência e a Tecnologia, Portugal

Sociedade Portuguesa de Química, Portugal
2021/10/21 - 2021/10/21 The EIT Health Innovation Day is a context where participants will be challenged to think innovatively about problems, design for entrepreneurship and communicate to specific audiences. Thus, it is intended that participants will develop skills: transdisciplinary analytical skills on health and aging problems; working in multidisciplinary teams towards transdisciplinarity; designing for entrepreneurship; communicating effectively; interaction of students with researchers.
Meeting
i-Days 2021 - INOVAÇÃO, TRANSDISCIPLINARIEDADE E EMPREENDORISMO
Universidade de Évora, Portugal

EIT Health, Germany

Association member

Society Organization name Role
2024/02 - Current Portuguese Society on Chemistry Associated Member
2023 - Current Portuguese Society of Biochemistry - Junior Section Foundation Member
2021 - Current Portuguese Society of Biochemistry Student Member
2012/02 - Current Portuguese Pharmacists Order - Lisbon Section Sócio

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Specialization fields: 1. Life Cycles of Medicines and Medical Devices 2. From Development to Market Introduction 3. Post-Market Introduction Topics: - Development of nanosystems for anti-proliferative studies of epidermal and dermal cells; - Fundamental bases of pre-clinical and clinical trials; - Clinical evaluation and quality assessment of medicines and medical devices. Pós-Graduação Ciclo de Vida do Medicamento e do Dispositivo Médico (Pós-Graduação) Universidade de Évora Escola de Saúde e Desenvolvimento Humano, Portugal

Mentoring / Tutoring

Topic Student name
2023/02 - 2023/05 Development of chitosan-zein nanoparticles as promising drug vehicles Eduardo Sécio
2021 - 2022 Desenvolvimento de nanopartículas de quitosano e avaliação de toxicidade em modelos in vitro Ian de Mello Rosa
2021/09 - 2021/12 Erasmus+ Programme Michaela Šedivá
2021/10/16 - 2021/11/14 Erasmus+ AltERnativo 2020 (2020-1-IT01-KA116-008233) Aminata Cisse; Chad Romaini; Francesco Marchetti; Sara Fabbri; Siham Kasmi
Distinctions

Award

2022 1st Place - StartUP PhD
Universidade de Évora, Portugal
2022 2nd Place - SCALE IT
Universidade de Évora, Portugal
2022 IMPACTO - Recognition for the Best Projects
Universidade de Évora, Portugal