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Henrik Zetterberg (HZ) is a Professor of Neurochemistry at the University of Gothenburg, Sweden, and University College London, UK, and a Clinical Chemist at Sahlgrenska University Hospital in Gothenburg, Sweden. He is Head of the Department of Psychiatry and Neurochemistry at the University of Gothenburg (80 employees) and leads the UK DRI Fluid Biomarker Laboratory at UCL (12 employees). His main research focus and clinical interest are fluid biomarkers for brain diseases.
Identificação

Identificação pessoal

Nome completo
Henrik Zetterberg

Nomes de citação

  • Zetterberg, Henrik

Identificadores de autor

Ciência ID
FC16-6F0D-5FA3
ORCID iD
0000-0003-3930-4354

Telefones

Telefone
  • (+46) 768-672647 (Profissional)

Moradas

  • Medicinaregatan 11, 413 90 , Göteborg, Göteborg, Suécia (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Neurologia Clínica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Sueco (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2006
Concluído
Specialist in Clinical Chemistry (Título de especialista)
Göteborgs Universitet, Suécia
2003
Concluído
Virology / Clinical Chemistry (Doktor (PhD))
Göteborgs Universitet, Suécia
1998
Concluído
Medicine (Doctor)
Göteborgs Universitet, Suécia
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2004 - 2005 Investigador (Investigação) Harvard Medical School, Estados Unidos
Harvard Medical School, Estados Unidos

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2012 - Atual Professor Catedrático (Docente Universitário) Institute of Neurology, University College London, Reino Unido
University College London Institute of Neurology Queen Square Multiple Sclerosis Centre, Reino Unido
2011 - Atual Professor Catedrático (Docente Universitário) Göteborgs Universitet, Suécia
Göteborgs Universitet, Suécia
2006 - 2011 Professor Associado (Docente Universitário) Göteborgs Universitet, Suécia
Göteborgs Universitet, Suécia

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2009 - Atual Presidente Göteborgs universitet Sahlgrenska Akademin, Suécia
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, University of Gothenburg, Suécia
2007 - 2009 Vice-Presidente Göteborgs universitet Sahlgrenska Akademin, Suécia
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, University of Gothenburg, Suécia

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2017 - Atual Consultant Sahlgrenska universitetssjukhuset Klinisk kemi, Suécia
Sahlgrenska universitetssjukhuset, Suécia
2006 - Atual Consultant Sahlgrenska universitetssjukhuset, Suécia
Sahlgrenska universitetssjukhuset Klinisk kemi, Suécia
Projetos

Bolsa

Designação Financiadores
2018 - 2023 New ideas on plaque can provide a functioning dementia medicine
Investigador responsável
Göteborgs Universitet, Suécia
Em curso
2020 - 2022 Blood Tests in Development - Moving Closer to Clinical Practice
Investigador responsável
Göteborgs Universitet, Suécia

Lunds Universitet, Suécia

Barcelonaßeta Brain Research Center, Espanha

Roche Diagnostics AS, Dinamarca
The Bill Gates Foundation

Alzheimer's Drug Discovery Foundation
Em curso
2019 - 2022 Vilka faktorer påverkar ansamling och toxicitet av beta-amyloid vid Alzheimers sjukdom?
#2018-02532
Investigador responsável
Göteborgs Universitet, Suécia
The Swedish Research Council
Em curso
2016/12/01 - 2021/11/30 Pathways to Alzheimer's disease
#681712
Investigador responsável
Göteborgs Universitet, Suécia
European Research Council
Em curso
2018 - 2021 Alzheimer
#ALFGBG-720931
Investigador responsável
Göteborgs Universitet, Suécia
Swedish State Support for Clinical Research
Em curso
2017 - 2021 Fluid biomarkers for neurodegenerative diseases
UKDRI-1003
Investigador responsável
UK Dementia Research Institute at UCL, Reino Unido
The Medical Research Council UK
Em curso
2018/06/30 - 2020/06/29 Neuropathological and amyloid peptide differences bewteen DS and familial AD with duplications and missensse mutations in APP gene
MR/S005145/1
Investigador responsável
University College London Institute of Neurology Queen Square Multiple Sclerosis Centre, Reino Unido
The Medical Research Council UK
Concluído
2019 - 2020 Plasma NfL in sports-related concussion
Investigador responsável
Göteborgs Universitet, Suécia
Hjärnfonden
Concluído
2017 - 2020 Microglia – potential therapeutic target to modify Alzheimer’s disease?
Investigador responsável
Olav Thon Foundation
Concluído
2014/01 - 2018/01 Pathways to Alzheimer's Disease
2013-2546
Vetenskapsradet
2014/01 - 2018/01 Pathways to Alzheimer's Disease
WAF
Knut Och Alice Wallenbergs Stiftelse
2017 - 2018 What role does microglial activation play in frontal lobe
Investigador responsável
Göteborgs Universitet, Suécia
Olav Thon Foundation
Concluído
2013 - 2018 Is Alzheimer's dementia caused by inflammation in the brain?
Investigador responsável
Göteborgs Universitet, Suécia
Knut Och Alice Wallenbergs Stiftelse
Concluído
2015/01 - 2017/01 Pathways to Alzheimer's Disease
441051
LUA-ALF
2015 - 2017 Roads to Alzheimer's disease
Investigador responsável
Karolinska Institutet, Suécia
Hjärnfonden
Concluído
Produções

Publicações

Artigo em revista
  1. Christel Pussinen; Mikko Anttonen; Lauri Wihersaari; Marjaana Tiainen; Matti Reinikainen; Johanna Hästbacka; Henrik Zetterberg; et al. "Neurofilament light chain evaluated with a new automated commercially available method for outcome prediction in out-of-hospital cardiac arrest patients". Resuscitation (2025): https://doi.org/10.1016/j.resuscitation.2025.110698.
    10.1016/j.resuscitation.2025.110698
  2. Jehyun Ahn; Eun Hye Lee; Heejin Yoo; Daeun Shin; Heekyoung Kang; Sohyun Yim; Seongmi Kim; et al. "Tailoring thresholds for interpreting plasma p-tau217 levels". Journal of Neurology, Neurosurgery & Psychiatry (2025): https://doi.org/10.1136/jnnp-2025-335830.
    10.1136/jnnp-2025-335830
  3. Isak Michaëlsson; Tobias Hallén; Dan Farahmand; Ubah Mahamud; Kaj Blennow; Henrik Zetterberg; Asgeir S. Jakola; Thomas Skoglund. "Assessing Brain Injury After Extra-Axial Brain Tumor Resection: Circulating Neurofilament Light Levels, Neurological Deficits, and Fatigue". Neurosurgery (2025): https://doi.org/10.1227/neu.0000000000003612.
    10.1227/neu.0000000000003612
  4. Jiarui Ao; Cynthia Picard; Daniel Auld; Henrik Zetterberg; Ann Brinkmalm; Kaj Blennow; Sylvia Villeneuve; et al. "Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease". Molecular Psychiatry (2025): https://doi.org/10.1038/s41380-024-02884-z.
    10.1038/s41380-024-02884-z
  5. Ali Al-Husseini; Yelverton Tegner; Kaj Blennow; Henrik Zetterberg; Niklas Marklund. "Effects of Selective Head-and-Neck Cooling on Brain Injury-Related Biomarker Levels and Symptom Rating Following a Boxing Bout: Protocol for an Exploratory Randomized Trial". JMIR Research Protocols (2025): https://doi.org/10.2196/68954.
    10.2196/68954
  6. Yuanmo Wang; Pankaj Gupta; Ajay Pradhan; Raphaël Trouillon; Jörg Hanrieder; Henrik Zetterberg; Ann-Sofie Cans. "Electrochemical Droplet Sculpturing of Short Carbon Fiber Nanotip Electrodes for Neurotransmitter Detection". ACS Electrochemistry (2025): https://doi.org/10.1021/acselectrochem.5c00135.
    10.1021/acselectrochem.5c00135
  7. Eleftheria Kodosaki; Henrik Zetterberg; Amanda Heslegrave. "Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis". Molecular Diagnosis & Therapy (2025): https://doi.org/10.1007/s40291-025-00789-3.
    10.1007/s40291-025-00789-3
  8. Jemma Hazan; Emily Abel; Miguel Rosa Grilo; Deborah Alawode; Ines Laranjinha; Amanda J Heslegrave; Kathy Y Liu; et al. "How well do plasma Alzheimer’s disease biomarkers reflect the CSF amyloid status?". Journal of Neurology, Neurosurgery & Psychiatry (2025): https://doi.org/10.1136/jnnp-2024-334122.
    10.1136/jnnp-2024-334122
  9. Michael T. Heneka; Serge Gauthier; Sagar Anil Chandekar; Julie Hviid Hahn-Pedersen; Marie A. Bentsen; Henrik Zetterberg. "Neuroinflammatory fluid biomarkers in patients with Alzheimer’s disease: a systematic literature review". Molecular Psychiatry (2025): https://doi.org/10.1038/s41380-025-02939-9.
    10.1038/s41380-025-02939-9
  10. Shuojia Yang; Brion S Maher; Adam P. Spira; Robert Yolken; Christos Davatzikos; Logan Dumitrescu; Guray Erus; et al. "Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration". Science Advances (2025): https://www.science.org/doi/10.1126/sciadv.adt7176.
    10.1126/sciadv.adt7176
  11. David López-Martos; Anna Brugulat-Serrat; Marc Suárez-Calvet; Marta Milà-Alomà; Carolina Minguillon; Juan Domingo Gispert; Henrik Zetterberg; et al. "Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer’s disease biomarkers.". Neuropsychology (2025): https://doi.org/10.1037/neu0001013.
    10.1037/neu0001013
  12. Chiara Rickenbach; Anna Mallone; Lars Häusle; Larissa Frei; Sarina Seiter; Colin Sparano; Tunahan Kirabali; et al. "Altered T-cell reactivity in the early stages of Alzheimer's disease". Brain (2025): https://doi.org/10.1093/brain/awaf167.
    10.1093/brain/awaf167
  13. Tim Lyckenvik; My Forsberg; Kalle Johansson; Markus Axelsson; Henrik Zetterberg; Kaj Blennow; Sebastian Illes; Pontus Wasling; Eric Hanse. "Ion concentrations in CSF and serum are differentially and precisely regulated". Brain Communications (2025): https://doi.org/10.1093/braincomms/fcaf201.
    10.1093/braincomms/fcaf201
  14. Sergio F Sharif; Dylan X Guan; Tamara Bodnar; Jeffery T Joseph; Henrik Zetterberg; Eric E Smith; Zahinoor Ismail. "Neuropsychiatric symptoms and progression to pathologically confirmed Alzheimer’s disease". Brain (2025): https://doi.org/10.1093/brain/awaf156.
    10.1093/brain/awaf156
  15. Srinivas Koutarapu; Junyue Ge; Maciej Dulewicz; Meera Srikrishna; Alicja Szadziewska; Jack Wood; Kaj Blennow; et al. "Chemical imaging delineates Aß plaque polymorphism across the Alzheimer’s disease spectrum". Nature Communications 16 1 (2025): https://doi.org/10.1038/s41467-025-59085-7.
    10.1038/s41467-025-59085-7
  16. Eleni Palpatzis; Muge Akinci; Marina Garcia-Prat; Kaj Blennow; Henrik Zetterberg; Clara Quijano-Rubio; Gwendlyn Kollmorgen; et al. "Grief and Economic Stressors by Sex, Gender, and Education". Neurology (2025): https://doi.org/10.1212/WNL.0000000000213377.
    10.1212/WNL.0000000000213377
  17. Clara Vila-Castelar; Muge Akinci; Eleni Palpatzis; Pablo Aguilar-Dominguez; Gregory Operto; Gwendlyn Kollmorgen; Clara Quijano-Rubio; et al. "Sex/gender effects of glial reactivity on preclinical Alzheimer’s disease pathology". Molecular Psychiatry (2025): https://doi.org/10.1038/s41380-024-02753-9.
    10.1038/s41380-024-02753-9
  18. Katharina Waury; Hlin Kvartsberg; Henrik Zetterberg; Kaj Blennow; Charlotte E. Teunissen; Sanne Abeln. "Data-driven evaluation of suitable immunogens for improved antibody selection". Protein Science (2025): https://doi.org/10.1002/pro.70100.
    10.1002/pro.70100
  19. Robert Sigström; Andreas Göteson; Erik Joas; Erik Pålsson; Benny Liberg; Axel Nordenskjöld; Kaj Blennow; Henrik Zetterberg; Mikael Landén. "Blood biomarkers of neuronal injury and astrocytic reactivity in electroconvulsive therapy". Molecular Psychiatry (2025): https://doi.org/10.1038/s41380-024-02774-4.
    10.1038/s41380-024-02774-4
  20. Ulla Knorr; Anja Hviid Simonsen; Johanna Nilsson; Ann Brinkmalm; Henrik Zetterberg; Kaj Blennow; Mark Bech Knudsen; et al. "Associations between cerebrospinal fluid synaptic protein biomarkers and cognitive function in bipolar disorder". Journal of Psychiatric Research (2025): https://doi.org/10.1016/j.jpsychires.2025.03.005.
    10.1016/j.jpsychires.2025.03.005
  21. Cristina Sanfilippo; Paola Castrogiovanni; Rosa Imbesi; Michele Vecchio; Manlio Vinciguerra; Kaj Blennow; Henrik Zetterberg; Michelino Di Rosa. "Sex-specific modulation of FOLR1 and its cycle enzyme genes in Alzheimer’s disease brain regions". Metabolic Brain Disease (2025): https://doi.org/10.1007/s11011-025-01578-x.
    10.1007/s11011-025-01578-x
  22. Antonio Terracciano; Keenan A Walker; Yang An; Murat Bilgel; Angelina R Sutin; Martina Luchetti; Selin Karakose; et al. "Loneliness and Biomarkers of Alzheimer’s Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts". The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences (2025): https://doi.org/10.1093/geronb/gbaf006.
    10.1093/geronb/gbaf006
  23. Lucia M Li; Eleftheria Kodosaki; Amanda Heslegrave; Henrik Zetterberg; Neil Graham; Karl Zimmerman; Eyal Soreq; et al. "High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury". Brain (2025): https://doi.org/10.1093/brain/awae305.
    10.1093/brain/awae305
  24. Sarah Akel; Markus Axelsson; Fredrik Asztely; Henrik Zetterberg; Johan Zelano. "Higher plasma neurofilament-light chain concentration in drug-resistant epilepsy". Brain Communications (2025): https://doi.org/10.1093/braincomms/fcaf108.
    10.1093/braincomms/fcaf108
  25. Gustaf Ulfhammer; Aylin Yilmaz; Åsa Mellgren; Erika Tyrberg; Erik Sörstedt; Lars Hagberg; Johanna Gostner; et al. "Asymptomatic Cerebrospinal Fluid HIV-1 Escape: Incidence and Consequences". The Journal of Infectious Diseases (2025): https://doi.org/10.1093/infdis/jiae555.
    10.1093/infdis/jiae555
  26. Galit Agmon; Sunghye Cho; Sharon Ash; Katheryn A. Q. Cousins; Kaj Blennow; Henrik Zetterberg; Leslie M. Shaw; et al. "Automatic quantification of syntactic complexity in natural spontaneous speech of people with primary progressive aphasia". Aphasiology (2025): https://doi.org/10.1080/02687038.2025.2462282.
    10.1080/02687038.2025.2462282
  27. Adam Al-Diwani; Nicholas M Provine; Andrew Murchison; Rhiannon Laban; Owen J Swann; Ivan Koychev; Fintan Sheerin; et al. "Neurodegenerative fluid biomarkers are enriched in human cervical lymph nodes". Brain (2025): https://doi.org/10.1093/brain/awae329.
    10.1093/brain/awae329
  28. Klara Andersson; Sarah Akel; Fredrik Asztély; David Larsson; Henrik Zetterberg; Johan Zelano. "Higher plasma total tau concentrations among patients reporting CNS-related side effects from antiseizure medication". Seizure: European Journal of Epilepsy (2025): https://doi.org/10.1016/j.seizure.2025.01.015.
    10.1016/j.seizure.2025.01.015
  29. Naoto Watamura; Martha S. Foiani; Sumi Bez; Mathieu Bourdenx; Alessia Santambrogio; Claire Frodsham; Elena Camporesi; et al. "In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds". Nature Neuroscience (2025): https://doi.org/10.1038/s41593-024-01829-7.
    10.1038/s41593-024-01829-7
  30. Jennie Olofsson; Sofia Bergström; Sára Mravinacová; Ulf Kläppe; Linn Öijerstedt; Henrik Zetterberg; Kaj Blennow; et al. "Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2025): https://doi.org/10.1080/21678421.2024.2428930.
    10.1080/21678421.2024.2428930
  31. Zefan Zhang; Pei Xue; Barbara B. Bendlin; Henrik Zetterberg; Fernanda De Felice; Xiao Tan; Christian Benedict. "Melatonin: A potential nighttime guardian against Alzheimer’s". Molecular Psychiatry (2025): https://doi.org/10.1038/s41380-024-02691-6.
    10.1038/s41380-024-02691-6
  32. Heekyoung Kang; Sook-Young Woo; Daeun Shin; Sohyun Yim; Eun Hye Lee; Hyunchul Ryu; Bora Chu; et al. "Reproducibility of Plasma Biomarker Measurements Across Laboratories: Insights Into ptau217, GFAP, and NfL". Dementia and Neurocognitive Disorders (2025): https://doi.org/10.12779/dnd.2025.24.2.91.
    10.12779/dnd.2025.24.2.91
  33. Kristian Steen Frederiksen; Xavier Morato Arus; Henrik Zetterberg; Serge Gauthier; Mercè Boada; Vanesa Pytel; Julie Hahn-Pedersen; Luis Rafael Solís Tarazona; Soeren Mattke. "Focusing on earlier diagnosis of Alzheimer's disease". Future Neurology (2024): https://doi.org/10.2217/fnl-2023-0024.
    10.2217/fnl-2023-0024
  34. Kristian Steen Frederiksen; Xavier Morato Arus; Henrik Zetterberg; Serge Gauthier; Mercé Boada; Julie Hahn-Pedersen; Luis Rafael Solís Tarazona; Soeren Mattke. "Focusing on earlier diagnosis of Alzheimer's disease: a plain language summary". Future Neurology (2024): https://doi.org/10.1080/14796708.2024.2419271.
    10.1080/14796708.2024.2419271
  35. Bryan Ng; Henrik Zetterberg. "Know your brain aging to know your resilience in neurodegenerative diseases". Brain Communications (2024): https://doi.org/10.1093/braincomms/fcae467.
    10.1093/braincomms/fcae467
  36. Vibeke Bratseth; Leiv Otto Watne; Bjørn Erik Neerland; Nathalie Bodd Halaas; Christian Thomas Pollmann; Adi Karabeg; Olav Tobias Odegaard; et al. "Increased cell-free DNA in CSF and serum of hip fracture patients with delirium". Brain Communications (2024): https://doi.org/10.1093/braincomms/fcae452.
    10.1093/braincomms/fcae452
  37. Lina Rydén; Nazib M Seidu; Hanna Wetterberg; Jenna Najar; Margda Waern; Silke Kern; Kaj Blennow; et al. "Polygenic risk scores for atrial fibrillation and heart failure and the risk of stroke and dementia". Brain Communications (2024): https://doi.org/10.1093/braincomms/fcae477.
    10.1093/braincomms/fcae477
  38. Michelle Safransky; Jenna R. Groh; Kaj Blennow; Henrik Zetterberg; Yorghos Tripodis; Brett Martin; Jason Weller; et al. "Lumipulse-Measured Cerebrospinal Fluid Biomarkers for the Early Detection of Alzheimer Disease". Neurology (2024): https://doi.org/10.1212/WNL.0000000000209866.
    10.1212/WNL.0000000000209866
  39. Gonzalez-Ortiz, Fernando; Holmegaard, Lukas; Andersson, Björn; Brännmark, Cecilia; Blomstrand, Christian; Zetterberg, Henrik; Jood, Katarina; et al. "Plasma brain-derived tau correlates with cerebral infarct volume". Journal of Internal Medicine 297 2 (2024): 173-185. https://doi.org/10.1111/joim.20041.
    10.1111/joim.20041
  40. Débora E Peretti; Cecilia Boccalini; Federica Ribaldi; Max Scheffler; Moira Marizzoni; Nicholas J Ashton; Henrik Zetterberg; et al. "Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive decline". Brain (2024): https://doi.org/10.1093/brain/awae211.
    10.1093/brain/awae211
  41. Marcus Clarin; Alexandra Hellberg; Kaj Blennow; Ulf Andreasson; Henrik Zetterberg. "Stability of bilirubin and oxyhaemoglobin in cerebrospinal fluid". Scandinavian Journal of Clinical and Laboratory Investigation (2024): https://doi.org/10.1080/00365513.2024.2442511.
    10.1080/00365513.2024.2442511
  42. Evgeniia Lobanova; Yu P. Zhang; Derya Emin; Jack Brelstaff; Lakmini Kahanawita; Maura Malpetti; Annelies Quaegebeur; et al. "ASC specks as a single-molecule fluid biomarker of inflammation in neurodegenerative diseases". Nature Communications (2024): https://doi.org/10.1038/s41467-024-53547-0.
    10.1038/s41467-024-53547-0
  43. Merete Wik-Klokk; Magnhild Rasmussen; Kristin Ørstavik; Henrik Zetterberg; Milada Hagen; Marie Elizabeth Holtebekk; Anette Ramm-Pettersen; Sean Wallace. "Type 1 spinal muscular atrophy treated with nusinersen in Norway, a five-year follow-up". European Journal of Paediatric Neurology (2024): https://doi.org/10.1016/j.ejpn.2024.09.009.
    10.1016/j.ejpn.2024.09.009
  44. Susanna Friberg; Caroline Lindblad; Frederick A. Zeiler; Henrik Zetterberg; Tobias Granberg; Per Svenningsson; Fredrik Piehl; Eric P. Thelin. "Fluid biomarkers of chronic traumatic brain injury". Nature Reviews Neurology (2024): https://doi.org/10.1038/s41582-024-01024-z.
    10.1038/s41582-024-01024-z
  45. Bárbara Fernandes Gomes; Atul Kumar; Nicholas J Ashton; Sara Hall; Erik Stomrud; Ruben Smith; Henrik Zetterberg; et al. "Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders". Brain Communications (2024): https://doi.org/10.1093/braincomms/fcae414.
    10.1093/braincomms/fcae414
  46. Sharmin, Tahmida; Chatterjee, Pratishtha; Doecke, James D.; Ashton, Nicholas J.; Huynh, Kevin; Pedrini, Steve; Sohrabi, Hamid R.; et al. "Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older adults". Journal of Neurochemistry 169 2 (2024): https://doi.org/10.1111/jnc.16244.
    10.1111/jnc.16244
  47. Makrina Daniilidou; Jasper Holleman; Göran Hagman; Ingemar Kåreholt; Malin Aspö; Ann Brinkmalm; Henrik Zetterberg; et al. "Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR study". Translational Psychiatry (2024): https://doi.org/10.1038/s41398-024-03072-x.
    10.1038/s41398-024-03072-x
  48. Christoph Linnemann; Carlo Wilke; David Mengel; Henrik Zetterberg; Carolin Heller; Jens Kuhle; Arabella Bouzigues; et al. "NfL reliability across laboratories, stage-dependent diagnostic performance and matrix comparability in genetic FTD: a large GENFI study". Journal of Neurology, Neurosurgery & Psychiatry (2024): https://doi.org/10.1136/jnnp-2023-332464.
    10.1136/jnnp-2023-332464
  49. Nicholas J. Ashton; Guglielmo Di Molfetta; Kübra Tan; Kaj Blennow; Henrik Zetterberg; Albee Messing. "Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander disease". Neurological Sciences (2024): https://doi.org/10.1007/s10072-024-07495-8.
    10.1007/s10072-024-07495-8
  50. Sofia Sandgren; Lenka Novakova; Anna Nordin; Hemin Sabir; Markus Axelsson; Clas Malmeström; Henrik Zetterberg; Jan Lycke. "The effect of alemtuzumab on neurodegeneration in relapsing-remitting multiple sclerosis: a five-year prospective mono-center study". Multiple Sclerosis and Related Disorders (2024): https://doi.org/10.1016/j.msard.2024.105894.
    10.1016/j.msard.2024.105894
  51. Francesco Bavato; Christian Barro; Laura K. Schnider; Joel Simrén; Henrik Zetterberg; Erich Seifritz; Boris B. Quednow. "Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls". Molecular Psychiatry (2024): https://doi.org/10.1038/s41380-024-02524-6.
    10.1038/s41380-024-02524-6
  52. Johanna Nilsson; Alexa Pichet Binette; Sebastian Palmqvist; Wagner S Brum; Shorena Janelidze; Nicholas J Ashton; Nicola Spotorno; et al. "Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases". Brain (2024): https://doi.org/10.1093/brain/awae032.
    10.1093/brain/awae032
  53. Katharina Bolsewig; Annemartijn A.J.M. van Unnik; Elena R. Blujdea; Maria C. Gonzalez; Nicholas J. Ashton; Dag Aarsland; Henrik Zetterberg; et al. "Association of Plasma Amyloid, P-Tau, GFAP, and NfL With CSF, Clinical, and Cognitive Features in Patients With Dementia With Lewy Bodies". Neurology (2024): https://doi.org/10.1212/WNL.0000000000209418.
    10.1212/WNL.0000000000209418
  54. Anna Dittrich; Eric Westman; Sara Shams; Tobias Skillbäck; Henrik Zetterberg; Kaj Blennow; Anna Zettergren; Ingmar Skoog; Silke Kern. "Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation". Neurology (2024): https://doi.org/10.1212/WNL.0000000000209402.
    10.1212/WNL.0000000000209402
  55. Marc James Quesnel; Anne Labonté; Cynthia Picard; Henrik Zetterberg; Kaj Blennow; Ann Brinkmalm; Sylvia Villeneuve; et al. "Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains". Brain (2024): https://doi.org/10.1093/brain/awad398.
    10.1093/brain/awad398
  56. Magdalena A Kolanko; Hanna Huber; Michael C B David; Laia Montoliu-Gaya; Joel Simrén; Kaj Blennow; Henrik Zetterberg; et al. "Quantification of neurofilament light and glial fibrillary acidic protein in finger-prick blood". Brain Communications (2024): https://doi.org/10.1093/braincomms/fcae151.
    10.1093/braincomms/fcae151
  57. Maria Boge Lauvsnes; Henrik Zetterberg; Kaj Blennow; Jan Terje Kvaløy; Anne Bolette Tjensvoll; Stian Maroni; Mona K. Beyer; et al. "Correction to: Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus". Journal of Neurology (2024): https://doi.org/10.1007/s00415-024-12238-y.
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  58. Ge Li; Jeffrey Iliff; Jane Shofer; Cynthia L. Mayer; James Meabon; David Cook; Kathleen F. Pagulayan; et al. "CSF ß-Amyloid and Tau Biomarker Changes in Veterans With Mild Traumatic Brain Injury". Neurology (2024): https://doi.org/10.1212/WNL.0000000000209197.
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  59. Bahira Shahim; Hong Xu; Kristina Haugaa; Henrik Zetterberg; Juliane Jurga; Dorota Religa; Maria Eriksdotter. "Cholinesterase inhibitors are associated with reduced mortality in patients with Alzheimer's disease and previous myocardial infarction". European Heart Journal - Cardiovascular Pharmacotherapy (2024): https://doi.org/10.1093/ehjcvp/pvad102.
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  60. Johan Gustafsson; Jonathan L. Robinson; Henrik Zetterberg; Jens Nielsen. "Brain energy metabolism is optimized to minimize the cost of enzyme synthesis and transport". Proceedings of the National Academy of Sciences (2024): https://doi.org/10.1073/pnas.2305035121.
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  61. Mariola Zapater-Fajarí; Patricia Diaz-Galvan; Nira Cedres; Therese Rydberg Sterner; Lina Rydén; Simona Sacuiu; Margda Waern; et al. "Biomarkers of Alzheimer’s Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline". The Journals of Gerontology: Series A (2024): https://doi.org/10.1093/gerona/glad216.
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  62. Johan Gobom; Ann Brinkmalm; Gunnar Brinkmalm; Kaj Blennow; Henrik Zetterberg. "Alzheimer's Disease Biomarker Analysis Using Targeted Mass Spectrometry". Molecular & Cellular Proteomics (2024): https://doi.org/10.1016/j.mcpro.2024.100721.
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  63. Monica T. Ly; Fatima Tuz-Zahra; Yorghos Tripodis; Charles H. Adler; Laura J. Balcer; Charles Bernick; Henrik Zetterberg; et al. "Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players". Neurology (2024): https://doi.org/10.1212/WNL.0000000000208030.
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  64. Carol Van Hulle; Selvi Ince; Ozioma C. Okonkwo; Barbara B. Bendlin; Sterling C. Johnson; Cynthia M. Carlsson; Sanjay Asthana; et al. "Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease". Translational Psychiatry (2024): https://doi.org/10.1038/s41398-023-02706-w.
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  65. Maxime Taquet; Zuzanna Skorniewska; Henrik Zetterberg; John R Geddes; Catherine J Mummery; James D Chalmers; Ling-Pei Ho; et al. "Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury". Brain Communications (2023): https://doi.org/10.1093/braincomms/fcad357.
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  66. Alok Bhan; Cecilie Jacobsen; Ingvild Dalen; Guido Alves; Niels Bergsland; Kjell-Morten Myhr; Henrik Zetterberg; et al. "Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study". Acta Neurologica Scandinavica (2023): https://doi.org/10.1155/2023/7136599.
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  67. Per Kristian Eide; Aslan Lashkarivand; Are Hugo Pripp; Lars Magnus Valnes; Markus Hovd; Geir Ringstad; Kaj Blennow; Henrik Zetterberg. "Mechanisms behind changes of neurodegeneration biomarkers in plasma induced by sleep deprivation". Brain Communications (2023): https://doi.org/10.1093/braincomms/fcad343.
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  68. Daniel Jons; Viktor Grut; Tomas Bergström; Henrik Zetterberg; Martin Biström; Martin Gunnarsson; Magnus Vrethem; et al. "Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage". Journal of Neurology, Neurosurgery & Psychiatry (2023): https://doi.org/10.1136/jnnp-2023-331868.
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  69. Sandra Roselli; Tugce Munise Satir; Rafael Camacho; Stefanie Fruhwürth; Petra Bergström; Henrik Zetterberg; Lotta Agholme. "APP-BACE1 Interaction and Intracellular Localization Regulate Aß Production in iPSC-Derived Cortical Neurons". Cellular and Molecular Neurobiology (2023): https://doi.org/10.1007/s10571-023-01374-0.
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  70. Stefanie Fruhwürth; Line S. Reinert; Carl Öberg; Marcelina Sakr; Marcus Henricsson; Henrik Zetterberg; Søren R. Paludan. "TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain". Science Advances (2023): https://doi.org/10.1126/sciadv.adf5808.
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  71. Marco Bucci; Marina Bluma; Irina Savitcheva; Nicholas J. Ashton; Konstantinos Chiotis; Anna Matton; Miia Kivipelto; et al. "Profiling of plasma biomarkers in the context of memory assessment in a tertiary memory clinic". Translational Psychiatry (2023): https://doi.org/10.1038/s41398-023-02558-4.
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  72. Linbin Dai; Feng Gao; Qiong Wang; Xinyi Lv; Zhaozhao Cheng; Yan Wu; Xianliang Chai; et al. "Molecules of senescent glial cells differentiate Alzheimer’s disease from ageing". Journal of Neurology, Neurosurgery & Psychiatry (2023): https://doi.org/10.1136/jnnp-2022-330743.
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  73. Ajay Kumar Nair; Carol A Van Hulle; Barbara B Bendlin; Henrik Zetterberg; Kaj Blennow; Norbert Wild; Gwendlyn Kollmorgen; et al. "Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline". Brain Communications (2023): https://doi.org/10.1093/braincomms/fcad180.
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  74. Tracy Butler; Liangdong Zhou; Ilker Ozsahin; Xiuyuan Hugh Wang; Jacob Garetti; Henrik Zetterberg; Kaj Blennow; et al. "Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma neurofilament light, a biomarker of injury severity". Brain Communications (2023): https://doi.org/10.1093/braincomms/fcad134.
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  75. Per Kristian Eide; Aslan Lashkarivand; Are Pripp; Lars Magnus Valnes; Markus Herberg Hovd; Geir Ringstad; Kaj Blennow; Henrik Zetterberg. "Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders". Nature Communications (2023): https://doi.org/10.1038/s41467-023-37685-5.
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  76. Enrico Ripamonti; Arvid Edén; Staffan Nilsson; Anders Sönnerborg; Henrik Zetterberg; Magnus Gisslén. "Longitudinal decline of plasma neurofilament light levels after antiretroviral initiation in people living with HIV". Journal of Internal Medicine (2023): https://doi.org/10.1111/joim.13594.
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  77. Elisa Lancini; Lena Haag; Franziska Bartl; Maren Rühling; Nicholas J Ashton; Henrik Zetterberg; Emrah Düzel; et al. "CSF and PET biomarkers for noradrenergic dysfunction in neurodegenerative diseases: a systematic review and meta-analysis". Brain Communications 5 3 (2023): https://doi.org/10.1093/braincomms/fcad085.
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  78. Charlotte Johansson; Steinunn Thordardottir; José Laffita-Mesa; Elena Rodriguez-Vieitez; Henrik Zetterberg; Kaj Blennow; Caroline Graff. "Plasma biomarker profiles in autosomal dominant Alzheimer’s disease". Brain (2023): https://doi.org/10.1093/brain/awac399.
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  79. Laura P. Kincer; Sarah Beth Joseph; Maria M. Gilleece; Blake M. Hauser; Sabrina Sizemore; Shuntai Zhou; Clara Di Germanio; et al. "Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus". Nature Microbiology (2023): https://doi.org/10.1038/s41564-022-01306-6.
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  80. Ulla Knorr; Anja Hviid Simonsen; Eva Letty Susanne Engström; Henrik Zetterberg; Kaj Blennow; Mira Willkan; Julie Forman; Steen Gregers Hasselbalch; Lars Vedel Kessing. "Associations between sleep quality and biomarkers for neurodegeneration - A longitudinal one-year case-control study of patients with bipolar disorder and healthy control individuals". Neuroscience Applied (2023): https://doi.org/10.1016/j.nsa.2022.101011.
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  81. Henrik Zetterberg; Charlotte Teunissen; John van Swieten; Jens Kuhle; Adam Boxer; Jonathan D Rohrer; Laura Mitic; et al. "The role of neurofilament light in genetic frontotemporal lobar degeneration". Brain Communications (2022): https://doi.org/10.1093/braincomms/fcac310.
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  82. Nanet Willumsen; Charles Arber; Christopher Lovejoy; Jamie Toombs; Argyro Alatza; Philip S J Weston; Lucia Chávez-Gutiérrez; et al. "The PSEN1 E280G mutation leads to increased amyloid-ß43 production in induced pluripotent stem cell neurons and deposition in brain tissue". Brain Communications 5 1 (2022): https://doi.org/10.1093/braincomms/fcac321.
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  83. Joana B. Pereira; Shorena Janelidze; Olof Strandberg; Christopher D. Whelan; Henrik Zetterberg; Kaj Blennow; Sebastian Palmqvist; et al. "Microglial activation protects against accumulation of tau aggregates in nondemented individuals with underlying Alzheimer’s disease pathology". Nature Aging (2022): https://doi.org/10.1038/s43587-022-00310-z.
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  84. Katharina Waury; Eline A. J. Willemse; Eugeen Vanmechelen; Henrik Zetterberg; Charlotte E. Teunissen; Sanne Abeln. "Bioinformatics tools and data resources for assay development of fluid protein biomarkers". Biomarker Research (2022): https://doi.org/10.1186/s40364-022-00425-w.
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  85. Erika Tyrberg; Lars Hagberg; Lars-Magnus Andersson; Staffan Nilsson; Aylin Yilmaz; Åsa Mellgren; Kaj Blennow; Henrik Zetterberg; Magnus Gisslén. "The effect of vitamin B supplementation on neuronal injury in people living with HIV: a randomized controlled trial". Brain Communications (2022): https://doi.org/10.1093/braincomms/fcac259.
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  86. Ashish Kumar; Mitu Sharma; Yixin Su; Sangeeta Singh; Fang-Chi Hsu; Bryan J Neth; Thomas C Register; et al. "Small extracellular vesicles in plasma reveal molecular effects of modified Mediterranean-ketogenic diet in participants with mild cognitive impairment". Brain Communications (2022): https://doi.org/10.1093/braincomms/fcac262.
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  87. Mahima Kapoor; Aisling Carr; Martha Foiani; Amanda Heslegrave; Henrik Zetterberg; Andrea Malaspina; Laura Compton; et al. "Association of plasma neurofilament light chain with disease activity in chronic inflammatory demyelinating polyradiculoneuropathy". European Journal of Neurology (2022): https://doi.org/10.1111/ene.15496.
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  88. Anniella Isgren; Andreas Göteson; Jessica Holmén-Larsson; Aurimantas Pelanis; Carl Sellgren; Erik Joas; Timea Sparding; et al. "Cerebrospinal fluid proteomic study of two bipolar disorder cohorts". Molecular Psychiatry (2022): https://doi.org/10.1038/s41380-022-01724-2.
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  89. Madeline S Morrison; Hugo J Aparicio; Kaj Blennow; Henrik Zetterberg; Nicholas J Ashton; Thomas K Karikari; Yorghos Tripodis; et al. "Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer’s disease neuropathology and regional tau at autopsy". Brain (2022): https://doi.org/10.1093/brain/awac175.
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  90. Srinivas Koutarapu; Junyue Ge; Durga Jha; Kaj Blennow; Henrik Zetterberg; Tammaryn Lashley; Wojciech Michno; Jörg Hanrieder. "Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease". Brain Connectivity (2022): https://doi.org/10.1089/brain.2022.0047.
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  91. Malgorzata M. Michalowska; Karl Herholz; Rainer Hinz; Chinenye Amadi; Lynn McInnes; Jose M. Anton-Rodriguez; Thomas K. Karikari; et al. "Evaluation of in vivo staging of amyloid deposition in cognitively unimpaired elderly aged 78–94". Molecular Psychiatry (2022): https://doi.org/10.1038/s41380-022-01685-6.
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  92. Anders Rosén; Mikael Gennser; Nicklas Oscarsson; Andreas Kvarnström; Göran Sandström; Helen Seeman-Lodding; Joel Simrén; Henrik Zetterberg. "Reply to Dr. Arieli regarding our article protein tau concentration in blood increases after SCUBA diving: an observational study published in European journal of applied physiology 2022;122:993-1005". European Journal of Applied Physiology (2022): https://doi.org/10.1007/s00421-022-04994-4.
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  93. Johan Zelano; Henrik Zetterberg. "Special issue on blood biomarkers in neurology". Acta Neurologica Scandinavica (2022): https://doi.org/10.1111/ane.13680.
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  94. Lieve T. van Egmond; Shervin Bukhari; Andrea Lessa Benedet; Nicholas J. Ashton; Elisa M. S. Meth; Alexander Boukas; Joachim Engström; et al. "Acute sleep loss increases CNS health biomarkers and compromises the ability to stay awake in a sex-and weight-specific manner". Translational Psychiatry (2022): https://doi.org/10.1038/s41398-022-02146-y.
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  95. Lina Bergman; Roxanne Hastie; Emma Bokström-Rees; Henrik Zetterberg; Kaj Blennow; Sonja Schell; Henrik Imberg; et al. "Cerebral biomarkers in neurologic complications of preeclampsia". American Journal of Obstetrics and Gynecology 227 2 (2022): 298.e1-298.e10. https://doi.org/10.1016/j.ajog.2022.02.036.
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  96. Ashvini Keshavan; Frankie O’Shea; Miles D Chapman; Melanie S Hart; Michael PT Lunn; Ross W Paterson; Jonathan D Rohrer; et al. "CSF biomarkers for dementia". Practical Neurology (2022): https://doi.org/10.1136/practneurol-2021-003310.
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  97. Paul C. Donaghy; Michael Firbank; George Petrides; Jim Lloyd; Nicola Barnett; Kirsty Olsen; Amanda Heslegrave; et al. "The relationship between plasma biomarkers and amyloid PET in dementia with Lewy bodies". Parkinsonism & Related Disorders (2022): https://doi.org/10.1016/j.parkreldis.2022.07.008.
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  98. Didac Vidal-Piñeiro; Øystein Sørensen; Kaj Blennow; Elettra Capogna; Nathalie Bodd Halaas; Ane-Victoria Idland; Athanasia Monica Mowinckel; et al. "Relationship between cerebrospinal fluid neurodegeneration biomarkers and temporal brain atrophy in cognitively healthy older adults". Neurobiology of Aging 116 (2022): 80-91. https://doi.org/10.1016/j.neurobiolaging.2022.04.010.
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  99. Hector Garcia-Moreno; Mercedes Prudencio; Gilbert Thomas-Black; Nita Solanky; Karen R. Jansen-West; Rana Hanna AL-Shaikh; Amanda Heslegrave; et al. "Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3". European Journal of Neurology (2022): https://doi.org/10.1111/ene.15373.
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  100. Nunzio Pomara; Davide Bruno; Chelsea Reichert Plaska; Jaime Ramos-Cejudo; Ricardo S. Osorio; Anilkumar Pillai; Bruno P. Imbimbo; Henrik Zetterberg; Kaj Blennow. "Plasma Amyloid-ß dynamics in late-life major depression: a longitudinal study". Translational Psychiatry (2022): https://doi.org/10.1038/s41398-022-02077-8.
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  101. Rakesh Kumar Banote; Samuel Håkansson; Henrik Zetterberg; Johan Zelano. "CSF biomarkers in patients with epilepsy in Alzheimer’s disease: a nation-wide study". Brain Communications (2022): https://doi.org/10.1093/braincomms/fcac210.
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  102. Henrik Zetterberg; Jonathan M. Schott. "Blood biomarkers for Alzheimer's disease and related disorders". Acta Neurologica Scandinavica 146 1 (2022): 51-55. https://doi.org/10.1111/ane.13628.
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  103. Lars Hagberg; Arvid Edén; Henrik Zetterberg; Richard W. Price; Magnus Gisslén. "Blood biomarkers for HIV infection with focus on neurologic complications—A review". Acta Neurologica Scandinavica 146 1 (2022): 56-60. https://doi.org/10.1111/ane.13629.
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  104. Syed Salman Shahid; Qiuting Wen; Shannon L Risacher; Martin R Farlow; Frederick W Unverzagt; Liana G Apostolova; Tatiana M Foroud; et al. "Hippocampal-subfield microstructures and their relation to plasma biomarkers in Alzheimer’s disease". Brain (2022): https://doi.org/10.1093/brain/awac138.
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  105. Emily M L Bowman; Christopher Cardwell; Daniel F McAuley; Bernadette McGuinness; Anthony P Passmore; David Beverland; Henrik Zetterberg; Jonathan M Schott; Emma L Cunningham. "Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery". British Journal of Surgery (2022): https://doi.org/10.1093/bjs/znac197.
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  106. Maria Boge Lauvsnes; Henrik Zetterberg; Kaj Blennow; Jan Terje Kvaløy; Anne Bolette Tjensvoll; Stian Maroni; Mona K. Beyer; et al. "Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus". Journal of Neurology (2022): https://doi.org/10.1007/s00415-021-10893-z.
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  107. Leonidas Chouliaras; Alan Thomas; Maura Malpetti; Paul Donaghy; Joseph Kane; Elijah Mak; George Savulich; et al. "Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy". Journal of Neurology, Neurosurgery & Psychiatry (2022): https://doi.org/10.1136/jnnp-2021-327788.
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  108. Daniel Jons; Henrik Zetterberg; Martin Biström; Lucia Alonso-Magdalena; Martin Gunnarsson; Magnus Vrethem; Kaj Blennow; et al. "Axonal injury in asymptomatic individuals preceding onset of multiple sclerosis". Annals of Clinical and Translational Neurology 9 6 (2022): 882-887. https://doi.org/10.1002/acn3.51568.
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  109. Johansson Kalle; Wasling Pontus; Novakova Lenka; Sjödin Simon; Brinkmalm Ann; Brinkmalm Gunnar; Blennow Kaj; Zetterberg Henrik; Axelsson Markus. "Cerebrospinal fluid amyloid precursor protein as a potential biomarker of fatigue in multiple sclerosis: A pilot study". Multiple Sclerosis and Related Disorders (2022): 103846-103846. https://doi.org/10.1016/j.msard.2022.103846.
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  110. Kristi Henjum; Leiv Otto Watne; Kristin Godang; Nathalie Bodd Halaas; Rannveig Saksholm Eldholm; Kaj Blennow; Henrik Zetterberg; et al. "Cerebrospinal fluid catecholamines in Alzheimer’s disease patients with and without biological disease". Translational Psychiatry (2022): https://doi.org/10.1038/s41398-022-01901-5.
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  111. Yuan Liu; Hua Zhang; Xiaofang Zhong; Zihui Li; Henrik Zetterberg; Lingjun Li. "Isotopic N,N-dimethyl leucine tags for absolute quantification of clusterin and apolipoprotein E in Alzheimer's disease". Journal of Proteomics (2022): https://doi.org/10.1016/j.jprot.2022.104507.
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  112. Anders Rosén; Mikael Gennser; Nicklas Oscarsson; Andreas Kvarnström; Göran Sandström; Helen Seeman-Lodding; Joel Simrén; Henrik Zetterberg. "Protein tau concentration in blood increases after SCUBA diving: an observational study". European Journal of Applied Physiology (2022): https://doi.org/10.1007/s00421-022-04892-9.
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  113. Margaret Parker; Marissa White; Cameron Casey; David Kunkel; Amber Bo; Kaj Blennow; Henrik Zetterberg; et al. "Cohort Analysis of the Association of Delirium Severity With Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies". The Journals of Gerontology: Series A 77 3 (2022): 494-501. https://doi.org/10.1093/gerona/glab203.
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  114. David Bäckström; Gabriel Granåsen; Susanna Jakobson Mo; Katrine Riklund; Miles Trupp; Henrik Zetterberg; Kaj Blennow; Lars Forsgren; Magdalena Eriksson Domellöf. "Prediction and early biomarkers of cognitive decline in Parkinson disease and atypical parkinsonism: a population-based study". Brain Communications 4 2 (2022): https://doi.org/10.1093/braincomms/fcac040.
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  115. Claire A. Leckey; Henrik Zetterberg. "Neurofilament light chain: defining the analyte". Brain Communications 4 2 (2022): https://doi.org/10.1093/braincomms/fcac070.
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  116. Mabel Seto; Emily R. Mahoney; Logan Dumitrescu; Vijay K. Ramanan; Corinne D. Engelman; Yuetiva Deming; Marilyn Albert; et al. "Exploring common genetic contributors to neuroprotection from amyloid pathology". Brain Communications 4 2 (2022): https://doi.org/10.1093/braincomms/fcac066.
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  117. Pashtun Shahim; Henrik Zetterberg. "Neurochemical Markers of Traumatic Brain Injury: Relevance to Acute Diagnostics, Disease Monitoring, and Neuropsychiatric Outcome Prediction". Biological Psychiatry (2022): https://doi.org/10.1016/j.biopsych.2021.10.010.
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  118. Correia, Manuel; Silva, Isabel; Gabriel, Denis; Simrén, Joel; Carneiro, Angelo; Ribeiro, Sara; Dória, Hugo Mota; et al. Autor correspondente: Maia, Luis F.. "Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes". European Journal of Neurology 29 6 (2022): 1630-1642. http://dx.doi.org/10.1111/ene.15273.
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  119. Wojciech Michno; Patrick M. Wehrli; Srinivas Koutarapu; Christian Marsching; Karolina Minta; Junyue Ge; Sven W. Meyer; et al. "Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging". Journal of Neurochemistry 160 4 (2022): 482-498. https://doi.org/10.1111/jnc.15557.
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  120. Saurabh Sihag; Sébastien Naze; Foad Taghdiri; Melisa Gumus; Charles Tator; Robin Green; Brenda Colella; et al. "Functional brain activity constrained by structural connectivity reveals cohort-specific features for serum neurofilament light chain". Communications Medicine (2022): https://doi.org/10.1038/s43856-021-00065-5.
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  121. Ulf Kläppe; Sanharib Chamoun; Qing Shen; Anja Finn; Björn Evertsson; Henrik Zetterberg; Kaj Blennow; et al. "Cardiac troponin T is elevated and increases longitudinally in ALS patients". Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23 1-2 (2022): 58-65. https://doi.org/10.1080/21678421.2021.1939384.
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  122. Elena Camporesi; Johanna Nilsson; Agathe Vrillon; Emmanuel Cognat; Claire Hourregue; Henrik Zetterberg; Kaj Blennow; et al. "Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry". eBioMedicine (2022): https://doi.org/10.1016/j.ebiom.2021.103793.
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  123. Gísli Gunnar Jónsson; Niklas Marklund; Kaj Blennow; Henrik Zetterberg; Anders Wanhainen; David Lindström; Jacob Eriksson; Kevin Mani. "Dynamics of Selected Biomarkers in Cerebrospinal Fluid During Complex Endovascular Aortic Repair – A Pilot Study". Annals of Vascular Surgery (2022): https://doi.org/10.1016/j.avsg.2021.04.034.
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  124. Martin F. Bjurström; Kaj Blennow; Henrik Zetterberg; Mikael Bodelsson; Markus Waldén; Nicholas Dietz; Sara Hall; et al. "Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain: associations with pain severity and central sensitization". PAIN Reports (2022): https://doi.org/10.1097/PR9.0000000000000988.
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  125. Joana B Pereira; Shorena Janelidze; Ruben Smith; Niklas Mattsson-Carlgren; Sebastian Palmqvist; Charlotte E Teunissen; Henrik Zetterberg; et al. "Plasma GFAP is an early marker of amyloid-ß but not tau pathology in Alzheimer’s disease". Brain 144 11 (2021): 3505-3516. https://doi.org/10.1093/brain/awab223.
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  126. Dimitrios Andreou; Kjetil Nordbø Jørgensen; Stener Nerland; Runar Elle Smelror; Kirsten Wedervang-Resell; Cecilie Haggag Johannessen; Anne Margrethe Myhre; et al. "Lower plasma total tau in adolescent psychosis: Involvement of the orbitofrontal cortex". Journal of Psychiatric Research 144 (2021): 255-261. https://doi.org/10.1016/j.jpsychires.2021.10.031.
    10.1016/j.jpsychires.2021.10.031
  127. Henrik Zetterberg. "Glial fibrillary acidic protein: a blood biomarker to differentiate neurodegenerative from psychiatric diseases". Journal of Neurology, Neurosurgery & Psychiatry 92 12 (2021): 1253-1253. https://doi.org/10.1136/jnnp-2021-326994.
    10.1136/jnnp-2021-326994
  128. Andreas Göteson; Anniella Isgren; Lina Jonsson; Timea Sparding; Erik Smedler; Aurimantas Pelanis; Henrik Zetterberg; et al. "Cerebrospinal fluid proteomics targeted for central nervous system processes in bipolar disorder". Molecular Psychiatry (2021): https://doi.org/10.1038/s41380-021-01236-5.
    10.1038/s41380-021-01236-5
  129. Mats Johnson; Elisabeth Fernell; Christopher Gillberg; Anders Fasth; Lisa Dinkler; Kaj Blennow; Henrik Zetterberg. "No neurochemical evidence of neuronal injury or glial activation in children with Paediatric Acute-onset Neuropsychiatric Syndrome. An explorative pilot study". The World Journal of Biological Psychiatry (2021): 1-5. https://doi.org/10.1080/15622975.2021.1907716.
    10.1080/15622975.2021.1907716
  130. Arvin Behzadi; Fani Pujol-Calderón; Anton E. Tjust; Anna Wuolikainen; Kina Höglund; Karin Forsberg; Erik Portelius; et al. "Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics". Scientific Reports (2021): https://doi.org/10.1038/s41598-021-01499-6.
    10.1038/s41598-021-01499-6
  131. Emily Hill; Thomas K. Karikari; Juan Lantero-Rodriguez; Henrik Zetterberg; Kaj Blennow; Magnus J. Richardson; Mark J. Wall. "Truncating tau reveals different pathophysiological actions of oligomers in single neurons". Communications Biology (2021): https://doi.org/10.1038/s42003-021-02791-x.
    10.1038/s42003-021-02791-x
  132. Pablo Lemercier; Andrea Vergallo; Simone Lista; Henrik Zetterberg; Kaj Blennow; Marie-Claude Potier; Marie-Odile Habert; et al. "Association of plasma Aß40/Aß42 ratio and brain Aß accumulation: testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer's disease". Neurobiology of Aging (2021): https://doi.org/10.1016/j.neurobiolaging.2021.07.005.
    10.1016/j.neurobiolaging.2021.07.005
  133. Joyce R. Chong; Nicholas J. Ashton; Thomas K. Karikari; Tomotaka Tanaka; Michael Schöll; Henrik Zetterberg; Kaj Blennow; Christopher P. Chen; Mitchell K.P. Lai. "Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances". Journal of Neurology, Neurosurgery & Psychiatry 92 11 (2021): 1231-1241. https://doi.org/10.1136/jnnp-2021-327370.
    10.1136/jnnp-2021-327370
  134. Igal Rosenstein; Sofia Rasch; Markus Axelsson; Lenka Novakova; Kaj Blennow; Henrik Zetterberg; Jan Lycke; et al. "Kappa free light chain index as a diagnostic biomarker in multiple sclerosis: A real-world investigation". Journal of Neurochemistry 159 3 (2021): 618-628. https://doi.org/10.1111/jnc.15500.
    10.1111/jnc.15500
  135. Wojciech Michno; Kaj Blennow; Henrik Zetterberg; Gunnar Brinkmalm. "Refining the amyloid ß peptide and oligomer fingerprint ambiguities in Alzheimer’s disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma". Journal of Neurochemistry (2021): https://doi.org/10.1111/jnc.15466.
    10.1111/jnc.15466
  136. Arvid Edén; Joel Simrén; Richard W. Price; Henrik Zetterberg; Magnus Gisslén. "Neurochemical biomarkers to study CNS effects of COVID-19: A narrative review and synthesis". Journal of Neurochemistry (2021): https://doi.org/10.1111/jnc.15459.
    10.1111/jnc.15459
  137. Eleni Gkanatsiou; Johanna Nilsson; Christina E. Toomey; Agathe Vrillon; Hlin Kvartsberg; Erik Portelius; Henrik Zetterberg; et al. "Amyloid pathology and synaptic loss in pathological aging". Journal of Neurochemistry (2021): https://doi.org/10.1111/jnc.15487.
    10.1111/jnc.15487
  138. Olli S Mattila; Nicholas J Ashton; Kaj Blennow; Henrik Zetterberg; Heini Harve-Rytsälä; Saana Pihlasviita; Juhani Ritvonen; et al. "Ultra-Early Differential Diagnosis of Acute Cerebral Ischemia and Hemorrhagic Stroke by Measuring the Prehospital Release Rate of GFAP". Clinical Chemistry (2021): https://doi.org/10.1093/clinchem/hvab128.
    10.1093/clinchem/hvab128
  139. Stefan Teipel; Davide Bruno; Chelsea Reichert Plaska; Amanda Heslegrave; Jaime Ramos-Cejudo; Ricardo S. Osorio; Henrik Zetterberg; Kaj Blennow; Nunzio Pomara. "Association of CSF sTREM2, a marker of microglia activation, with cholinergic basal forebrain volume in major depressive disorder". Journal of Affective Disorders (2021): https://doi.org/10.1016/j.jad.2021.06.030.
    10.1016/j.jad.2021.06.030
  140. Petra Bergström; Edward Trybala; Charlotta E Eriksson; Maria Johansson; Tugce Munise Satir; Sibylle Widéhn; Stefanie Fruhwürth; et al. "Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons". Viruses (2021): https://www.mdpi.com/1999-4915/13/10/2072.
    10.3390/v13102072
  141. Jodie Lord; Anna Zettergren; Nicholas J. Ashton; Thomas K. Karikari; Andrea L. Benedet; Joel Simrén; Abdul Hye; et al. "A genome-wide association study of plasma phosphorylated tau181". Neurobiology of Aging 106 (2021): 304.e1-304.e3. https://doi.org/10.1016/j.neurobiolaging.2021.04.018.
    10.1016/j.neurobiolaging.2021.04.018
  142. Jasmine Chebli; Maryam Rahmati; Tammaryn Lashley; Brigitta Edeman; Anders Oldfors; Henrik Zetterberg; Alexandra Abramsson. "The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish". Scientific Reports (2021): https://doi.org/10.1038/s41598-021-98487-7.
    10.1038/s41598-021-98487-7
  143. Jasmini Alagaratnam; Wolfgang Stöhr; Jamie Toombs; Amanda Heslegrave; Henrik Zetterberg; Magnus Gisslén; Sarah Pett; et al. "No evidence of neuronal damage as measured by neurofilament light chain in a HIV cure study utilising a kick-and-kill approach". Journal of Virus Eradication (2021): https://doi.org/10.1016/j.jve.2021.100056.
    10.1016/j.jve.2021.100056
  144. Hanna Eriksson; Rakesh Kumar Banote; David Larsson; Kaj Blennow; Henrik Zetterberg; Johan Zelano. "Brain injury markers in new-onset seizures in adults: a pilot study". Seizure (2021): https://doi.org/10.1016/j.seizure.2021.08.012.
    10.1016/j.seizure.2021.08.012
  145. Alberto Lleó; Henrik Zetterberg; Jordi Pegueroles; Thomas K. Karikari; María Carmona-Iragui; Nicholas J. Ashton; Victor Montal; et al. "Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome". Nature Communications (2021): https://doi.org/10.1038/s41467-021-24319-x.
    10.1038/s41467-021-24319-x
  146. Wojciech Michno; Katie M. Stringer; Thomas Enzlein; Melissa K. Passarelli; Stephane Escrig; Karina Vitanova; Jack Wood; et al. "Following spatial Aß aggregation dynamics in evolving Alzheimer’s disease pathology by imaging stable isotope labeling kinetics". Science Advances 7 25 (2021): https://doi.org/10.1126/sciadv.abg4855.
    10.1126/sciadv.abg4855
  147. Gunnar Brinkmalm; Henrik Zetterberg. "The phosphorylation cascade hypothesis of Alzheimer’s disease". Nature Aging (2021): https://doi.org/10.1038/s43587-021-00077-9.
    10.1038/s43587-021-00077-9
  148. Jasmini Alagaratnam; Sophia von Widekind; Davide De Francesco; Jonathan Underwood; Paul Edison; Alan Winston; Henrik Zetterberg; Sarah Fidler. "Correlation between CSF and blood neurofilament light chain protein: a systematic review and meta-analysis". BMJ Neurology Open (2021): https://doi.org/10.1136/bmjno-2021-000143.
    10.1136/bmjno-2021-000143
  149. Sebastian Palmqvist; Pontus Tideman; Nicholas Cullen; Henrik Zetterberg; Kaj Blennow; Jeffery L. Dage; Erik Stomrud; et al. "Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures". Nature Medicine (2021): https://doi.org/10.1038/s41591-021-01348-z.
    10.1038/s41591-021-01348-z
  150. Isabelle Weinhofer; Paulus Rommer; Bettina Zierfuss; Patrick Altmann; Martha Foiani; Amanda Heslegrave; Henrik Zetterberg; et al. "Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy". Nature Communications (2021): https://doi.org/10.1038/s41467-021-22114-2.
    10.1038/s41467-021-22114-2
  151. Christian Barro; Henrik Zetterberg. "Neurological symptoms and blood neurofilament light levels". Acta Neurologica Scandinavica (2021): https://doi.org/10.1111/ane.13415.
    10.1111/ane.13415
  152. Lukas Holmegaard; Tara M. Stanne; Ulf Andreasson; Henrik Zetterberg; Kaj Blennow; Christian Blomstrand; Katarina Jood; Christina Jern. "Proinflammatory protein signatures in cryptogenic and large artery atherosclerosis stroke". Acta Neurologica Scandinavica (2021): https://doi.org/10.1111/ane.13366.
    10.1111/ane.13366
  153. Charles Arber; Argyro Alatza; Claire A. Leckey; Ross W. Paterson; Henrik Zetterberg; Selina Wray; Arber, Charles; et al. "Mass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer’s disease and dementia". Journal of Neurochemistry 159 2 (2021): 305-317. https://doi.org/10.1111/jnc.15315.
    10.1111/jnc.15315
  154. Richeng Jiang; Una Smailovic; Hazal Haytural; Robert Haret; Ganna Shevchenko; Betty Tijms; Johan Gobom; et al. "Decorin is an early CSF biomarker of Alzheimers Aß amyloidosis". Nature Portfolio (2021): https://doi.org/10.21203/rs.3.rs-275229/v1.
    Em revisão • 10.21203/rs.3.rs-275229/v1
  155. Henrik Zetterberg; Erik Stomrud. "Alzheimer’s disease in primary care: new tools for improved and simplified diagnostics". Journal of Internal Medicine (2021): https://doi.org/10.1111/joim.13249.
    10.1111/joim.13249
  156. Patrick Garland; Matt Morton; Ardalan Zolnourian; Andrew Durnford; Ben Gaastra; Jamie Toombs; Amanda J Heslegrave; et al. "Neurofilament light predicts neurological outcome after subarachnoid haemorrhage". Brain (2021): https://doi.org/10.1093/brain/awaa451.
    10.1093/brain/awaa451
  157. Nicholas C. Cullen; Antoine Leuzy; Sebastian Palmqvist; Shorena Janelidze; Erik Stomrud; Pedro Pesini; Leticia Sarasa; et al. "Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations". Nature Aging (2021): https://doi.org/10.1038/s43587-020-00003-5.
    10.1038/s43587-020-00003-5
  158. Ingmar Skoog; Silke Kern; Jenna Najar; Rita Guerreiro; Jose Bras; Margda Waern; Henrik Zetterberg; et al. "A Non-APOE Polygenic Risk Score for Alzheimer’s Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds". The Journals of Gerontology: Series A (2021): https://doi.org/10.1093/gerona/glab030.
    10.1093/gerona/glab030
  159. Sebastian Wiberg; Frederik Holmgaard; Kaj Blennow; Jens C Nilsson; Jesper Kjaergaard; Michael Wanscher; Annika R Langkilde; et al. "Associations between mean arterial pressure during cardiopulmonary bypass and biomarkers of cerebral injury in patients undergoing cardiac surgery: secondary results from a randomized controlled trial". Interactive CardioVascular and Thoracic Surgery (2021): https://doi.org/10.1093/icvts/ivaa264.
    10.1093/icvts/ivaa264
  160. Karolina Minta; Gunnar Brinkmalm; Eric P. Thelin; Faiez Al Nimer; Fredrik Piehl; Mats Tullberg; Anna Jeppsson; et al. "Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury". Clinica Chimica Acta 512 (2021): 74-83. https://doi.org/10.1016/j.cca.2020.11.017.
    10.1016/j.cca.2020.11.017
  161. Anna Lybeck; Hans Friberg; Niklas Nielsen; Malin Rundgren; Susann Ullén; Henrik Zetterberg; Kaj Blennow; Tobias Cronberg; Erik Westhall. "Postanoxic electrographic status epilepticus and serum biomarkers of brain injury". Resuscitation 158 (2021): 253-257. https://doi.org/10.1016/j.resuscitation.2020.10.027.
    10.1016/j.resuscitation.2020.10.027
  162. Faisal Hayat Nazir; Elena Camporesi; Gunnar Brinkmalm; Tammaryn Lashley; Christina E. Toomey; Hlin Kvartsberg; Henrik Zetterberg; Kaj Blennow; Bruno Becker. "Molecular forms of neurogranin in cerebrospinal fluid". Journal of Neurochemistry (2020): https://doi.org/10.1111/jnc.15252.
    10.1111/jnc.15252
  163. Wei Jiang; Zhenwu Luo; Sophie Stephenson; Hong Li; Clara Di Germanio; Philip J Norris; Dietmar Fuchs; et al. "Cerebrospinal Fluid and Plasma Lipopolysaccharide Levels in Human Immunodeficiency Virus Type 1 Infection and Associations With Inflammation, Blood-Brain Barrier Permeability, and Neuronal Injury". The Journal of Infectious Diseases (2020): https://doi.org/10.1093/infdis/jiaa765.
    10.1093/infdis/jiaa765
  164. Kieran Austin; Ben J Lee; Tessa R Flood; Jamie Toombs; Mina Borisova; Mike Lauder; Amanda Heslegrave; Henrik Zetterberg; Neal a Smith. "Serum neurofilament light concentration does not increase following exposure to low velocity football heading". Science and Medicine in Football (2020): https://doi.org/10.1080/24733938.2020.1853210.
    10.1080/24733938.2020.1853210
  165. Anna Gard; Niklas Lehto; Åsa Engström; Pashtun Shahim; Henrik Zetterberg; Kaj Blennow; Niklas Marklund; Yelverton Tegner. "Quality of life of ice hockey players after retirement due to concussions". Concussion (2020): CNC78-CNC78. https://doi.org/10.2217/cnc-2020-0007.
    10.2217/cnc-2020-0007
  166. Daniel Jons; Henrik Zetterberg; Clas Malmeström; Tomas Bergström; Markus Axelsson; Kaj Blennow; Måns Thulin; Peter Sundström; Oluf Andersen. "Intrathecal immunoreactivity in people with or without previous infectious mononucleosis". Acta Neurologica Scandinavica 142 2 (2020): 161-168. https://doi.org/10.1111/ane.13280.
    10.1111/ane.13280
  167. Grant L. Iverson; Jussi P. Posti; Juha Öhman; Kaj Blennow; Henrik Zetterberg; Teemu Miikka Luoto. "Reliability of serum S100B measurement following mild traumatic brain injury: a comparison of assay measurements from two laboratories". Brain Injury (2020): 1-8. https://doi.org/10.1080/02699052.2020.1800092.
    10.1080/02699052.2020.1800092
  168. Henrik Zetterberg. "Neurofilament light in blood – What more is needed for clinical implementation in multiple sclerosis?". EBioMedicine 57 (2020): 102826-102826. https://doi.org/10.1016/j.ebiom.2020.102826.
    10.1016/j.ebiom.2020.102826
  169. N. David Åberg; Alexander Wall; Olof Anger; Katarina Jood; Ulf Andreasson; Kaj Blennow; Henrik Zetterberg; et al. "Circulating levels of vascular endothelial growth factor and post-stroke long-term functional outcome". Acta Neurologica Scandinavica (2020): https://doi.org/10.1111/ane.13219.
    10.1111/ane.13219
  170. Wojciech Michno; Patrick Wehrli; Silvio R. Meier; Dag Sehlin; Stina Syvänen; Henrik Zetterberg; Kaj Blennow; Jörg Hanrieder. "Chemical imaging of evolving amyloid plaque pathology and associated Aß peptide aggregation in a transgenic mouse model of Alzheimer’s disease". Journal of Neurochemistry (2020): https://doi.org/10.1111/jnc.14888.
    10.1111/jnc.14888
  171. Lars Hagberg; Richard W. Price; Henrik Zetterberg; Dietmar Fuchs; Magnus Gisslén. "Proteomic blood profiling in mild, severe and critical COVID-19 patients". Scientific Reports (2020): https://doi.org/10.1101/2020.01.28.922690.
    10.1101/2020.01.28.922690
  172. Henrik Zetterberg. "Plasma neurofilament light in progressive multiple sclerosis". Acta Neurologica Scandinavica (2020): https://doi.org/10.1111/ane.13184.
    10.1111/ane.13184
  173. Aylin Yilmaz; Åsa Mellgren; Dietmar Fuchs; Staffan Nilsson; Kaj Blennow; Henrik Zetterberg; Magnus Gisslén. "Switching from a regimen containing abacavir/lamivudine or emtricitabine/tenofovir disoproxil fumarate to emtricitabine/tenofovir alafenamide fumarate does not affect central nervous system HIV-1 infection". Infectious Diseases 51 11-12 (2019): 838-846. https://doi.org/10.1080/23744235.2019.1670352.
    10.1080/23744235.2019.1670352
  174. Henrik Zetterberg; Samantha C. Burnham. "Blood-based molecular biomarkers for Alzheimer’s disease". Molecular Brain 12 1 (2019): https://doi.org/10.1186/s13041-019-0448-1.
    10.1186/s13041-019-0448-1
  175. Wojciech Michno; Patrick M. Wehrli; Kaj Blennow; Henrik Zetterberg; Jörg Hanrieder. "Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology". Journal of Neurochemistry (2019): https://doi.org/10.1111/jnc.14559.
    10.1111/jnc.14559
  176. Rakesh Kumar Banote; Jasmine Chebli; Tugçe Munise Satir; Gaurav K. Varshney; Rafael Camacho; Johan Ledin; Shawn M. Burgess; Alexandra Abramsson; Henrik Zetterberg. "Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish". Scientific Reports 10 10127 (2019): https://doi.org/10.1101/795187.
    Publicado • 10.1101/795187
  177. L. Rydén; A. Zettergren; N. M. Seidu; X. Guo; S. Kern; K. Blennow; H. Zetterberg; S. Sacuiu; I. Skoog. "Atrial fibrillation increases the risk of dementia amongst older adults even in the absence of stroke". Journal of Internal Medicine 286 1 (2019): 101-110. https://doi.org/10.1111/joim.12902.
    10.1111/joim.12902
  178. H. Zetterberg; B. Winblad; C. Bernick; K. Yaffe; M. Majdan; G. Johansson; V. Newcombe; et al. "Head trauma in sports – clinical characteristics, epidemiology and biomarkers". Journal of Internal Medicine 285 6 (2019): 624-634. https://doi.org/10.1111/joim.12863.
    10.1111/joim.12863
  179. B. Winblad; M. Ankarcrona; G. Johansson; P. Novak; E. Peter Thelin; H. Zetterberg; K. Blennow. "Head trauma in sports and risk for dementia". Journal of Internal Medicine 285 6 (2019): 591-593. https://doi.org/10.1111/joim.12918.
    10.1111/joim.12918
  180. My Forsberg; Henrik Seth; Andreas Björefeldt; Tim Lyckenvik; Mats Andersson; Pontus Wasling; Henrik Zetterberg; Eric Hanse. "Ionized calcium in human cerebrospinal fluid and its influence on intrinsic and synaptic excitability of hippocampal pyramidal neurons in the rat". Journal of Neurochemistry (2019): https://doi.org/10.1111/jnc.14693.
    10.1111/jnc.14693
  181. Zetterberg, Henrik; Arber C,; Wray S. "Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta". Mol Psychiatry 25 11 (2019): 2919-2931.
  182. H. Zetterberg; J. C. van Swieten; A. L. Boxer; J. D. Rohrer. "Review: Fluid biomarkers for frontotemporal dementias". Neuropathology and Applied Neurobiology (2019): https://doi.org/10.1111/nan.12530.
    10.1111/nan.12530
  183. Mats Ribbe; Silke Kern; Anne Börjesson Hansson; Svante Östling; Henrik Zetterberg; Kaj Blennow; Ingmar Skoog. "Amyloid ß42 and Total Tau Levels in Cerebrospinal Fluid Associate with Survival in an 85-Year-Old Population-Based Cohort Followed until Death". Dementia and Geriatric Cognitive Disorders 47 1-2 (2019): 114-124. https://doi.org/10.1159/000499066.
    10.1159/000499066
  184. Brinkmalm, Ann; Portelius, Erik; Brinkmalm, Gunnar; Pannee, Josef; Dahlén, Rahil; Gobom, Johan; Blennow, Kaj; et al. "Fluid-based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases". Journal of Neurochemistry 151 4 (2018): 417-434. https://doi.org/10.1111/jnc.14594.
    10.1111/jnc.14594
  185. Zetterberg, Henrik; Magnus Gisslén. "CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection". Neurol Neuroimmunol Neuroinflamm 6 1 (2018): https://nn.neurology.org/content/6/1/e512.abstract.
    Acesso aberto • Publicado
  186. Zetterberg, Henrik; Lauren M. Byrne; Edward J. Wild. "Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.". Science translational medicin 10 458 (2018): https://stm.sciencemag.org/content/10/458/eaat7108.short.
    Acesso aberto • Publicado
  187. Lenka Novakova; Avadhesh Kumar Singh; Markus Axelsson; Marcus Ståhlman; Martin Adiels; Clas Malmeström; Henrik Zetterberg; et al. "Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS". Journal of Neurochemistry 146 3 (2018): 322-332. https://doi.org/10.1111/jnc.14452.
    10.1111/jnc.14452
  188. Kirsten Mehlig; Leif Lapidus; Dag S. Thelle; Margda Waern; Henrik Zetterberg; Cecilia Björkelund; Ingmar Skoog; Lauren Lissner. "Low fasting serum insulin and dementia in nondiabetic women followed for 34 years". Neurology 91 5 (2018): e427-e435. https://doi.org/10.1212/WNL.0000000000005911.
    10.1212/WNL.0000000000005911
  189. Lena Johansson; Silke Kern; Henrik Zetterberg; Kaj Blennow; Anne Börjesson-Hansson; Lars Rosengren; Xinxin Guo; Ingmar Skoog. "Midlife Stress in Relation to Late-Life Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease: A 25-Year Follow-Up Study". Dementia and Geriatric Cognitive Disorders 46 1-2 (2018): 90-99. https://doi.org/10.1159/000490885.
    10.1159/000490885
  190. Nathalie Bodd Halaas; Kaj Blennow; Ane-Victoria Idland; Torgeir Bruun Wyller; Johan Ræder; Frede Frihagen; Anne Cathrine Staff; Henrik Zetterberg; Leiv Otto Watne. "Neurofilament Light in Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium". Dementia and Geriatric Cognitive Disorders 46 5-6 (2018): 346-357. https://doi.org/10.1159/000494754.
    10.1159/000494754
  191. Karen Roksund Hov; Nils Bolstad; Ane-Victoria Idland; Henrik Zetterberg; Kaj Blennow; Farrukh A. Chaudhry; Frede Frihagen; et al. "Cerebrospinal Fluid S100B and Alzheimer’s Disease Biomarkers in Hip Fracture Patients with Delirium". Dementia and Geriatric Cognitive Disorders Extra 7 3 (2017): 374-385. https://doi.org/10.1159/000481853.
    10.1159/000481853
  192. Zetterberg, Henrik. "Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration". Neurology 89 21 (2017): 2167-2175. https://n.neurology.org/content/89/21/2167.short.
    Acesso aberto • Publicado
  193. Annika Öhrfelt; Per Johansson; Anders Wallin; Ulf Andreasson; Henrik Zetterberg; Kaj Blennow; Johan Svensson. "Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease". Dementia and Geriatric Cognitive Disorders Extra 6 2 (2016): 283-294. https://doi.org/10.1159/000447239.
    10.1159/000447239
  194. Zetterberg, Henrik. "CSF and blood biomarkers for Alzheimer’s". The Lancet Neurology 15 7 (2016): 673-684.
    Publicado
  195. Camilla Steen Jensen; Erik Portelius; Volkert Siersma; Peter Høgh; Lene Wermuth; Kaj Blennow; Henrik Zetterberg; et al. "Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer Disease". Dementia and Geriatric Cognitive Disorders 42 3-4 (2016): 146-158. https://doi.org/10.1159/000449408.
    10.1159/000449408
  196. Erik Portelius; Tammaryn Lashley; Anni Westerlund; Rita Persson; Nick C. Fox; Kaj Blennow; Tamas Revesz; Henrik Zetterberg. "Brain Amyloid-Beta Fragment Signatures in Pathological Ageing and Alzheimer's Disease by Hybrid Immunoprecipitation Mass Spectrometry". Neurodegenerative Diseases (2015): https://doi.org/10.1159/000369465.
    10.1159/000369465
  197. Maria Bjerke; Michael Jonsson; Arto Nordlund; Carl Eckerström; Kaj Blennow; Henrik Zetterberg; Leonardo Pantoni; et al. "Cerebrovascular Biomarker Profile Is Related to White Matter Disease and Ventricular Dilation in a LADIS Substudy". Dementia and Geriatric Cognitive Disorders Extra 4 3 (2014): 385-394. https://doi.org/10.1159/000366119.
    10.1159/000366119
  198. Christoffer Rosén; Carl-Henrik Andersson; Ulf Andreasson; José L. Molinuevo; Maria Bjerke; Lorena Rami; Albert Lladó; Kaj Blennow; Henrik Zetterberg. "Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease". Dementia and Geriatric Cognitive Disorders Extra (2014): https://doi.org/10.1159/000362164.
    10.1159/000362164
Pré-impressão
  1. Tim Lyckenvik; Martin Olsson; My Forsberg; Pontus Wasling; Henrik Zetterberg; Jan Hedner; Eric Hanse. "Slow Wave Sleep Reduces CSF Concentrations of Beta-amyloid and Tau: A Randomized Crossover Study in Healthy Adults". 2025. https://doi.org/10.1101/2025.06.15.659740.
    10.1101/2025.06.15.659740
  2. Anita Sunde; Dag Aarsland; Antoine Leuzy; Diego Tovar-Rios; Tormod Fladby; Henrik Zetterberg; Kaj Blennow; et al. "Prevalence of Alzheimer's Disease Pathology in the Community – The HUNT Study". 2025. https://doi.org/10.21203/rs.3.rs-6153769/v1.
    10.21203/rs.3.rs-6153769/v1
  3. Ali Al-Husseini; Yelverton Tegner; Kaj Blennow; Henrik Zetterberg; Niklas Marklund. "Effects of Selective Head-and-Neck Cooling on Brain Injury-Related Biomarker Levels and Symptom Rating Following a Boxing Bout: Protocol for an Exploratory Randomized Trial (Preprint)". 2024. https://doi.org/10.2196/preprints.68954.
    10.2196/preprints.68954
  4. Matthew JY Kang; Dhamidhu Eratne; Samantha M Loi; Christa Dang; Alexander F Santillo; Henrik Zetterberg; Kaj Blennow; et al. "Apathy and Affective Symptoms Associated with Elevated Alzheimer’s Disease Biomarkers". 2024. https://doi.org/10.1101/2024.11.06.24316730.
    10.1101/2024.11.06.24316730
  5. Hannah Dobson; Said Al Maawali; Charles Malpas; Alexander F Santillo; Matthew Kang; Marian Todaro; Rosie Watson; et al. "Elevated plasma neurofilament light & glial fibrillary acidic protein in epilepsy versus non-epileptic seizures & non-epileptic disorders". 2024. https://doi.org/10.1101/2024.02.19.24303018.
    10.1101/2024.02.19.24303018
  6. Elettra Capogna; Øystein Sørensen; Leiv Otto Watne; James Roe; Marie Strømstad; Ane Victoria Idland; Nathalie Bodd Halaas; et al. "Subtypes of brain change in aging and their associations with cognition and Alzheimer’s disease biomarkers". 2024. https://doi.org/10.1101/2024.03.04.583291.
    10.1101/2024.03.04.583291
  7. Dhamidhu Eratne; Matthew JY Kang; Courtney Lewis; Christa Dang; Charles Malpas; Suyi Ooi; Amy Brodtmann; et al. "Plasma glial fibrillary acidic protein and neurofilament light chain in behavioural variant frontotemporal dementia and primary psychiatric disorders". 2024. https://doi.org/10.1101/2024.08.08.24311409.
    10.1101/2024.08.08.24311409
  8. Makrina Daniilidou; Jasper Holleman; Göran Hagman; Ingemar Kåreholt; Shireen Sindi; Malin Aspö; Ann Brinkmalm; et al. "Diurnal cortisol, neuroinflammation and cerebrovascular dysfunction biomarkers in a memory clinic cohort: findings from the Co-STAR study". 2023. https://doi.org/10.21203/rs.3.rs-3282795/v1.
    10.21203/rs.3.rs-3282795/v1
  9. S Toniolo; S Zhao; A Scholcz; B Amein; A Ganse-Dumrath; A J Heslegrave; S Thompson; et al. "Digital cognitive test performance and relationship to plasma biomarkers in Alzheimer’s disease". 2023. https://doi.org/10.1101/2023.08.21.23293786.
    10.1101/2023.08.21.23293786
  10. Gemma Salvadó; Rik Ossenkoppele; Nicholas J. Ashton; Thomas G. Beach; Geidy E. Serrano; Henrik Zetterberg; Niklas Mattsson-Carlgren; et al. "Specific associations between plasma biomarkers and post-mortem amyloid plaque and neurofibrillary tau tangle loads". 2022. https://doi.org/10.1101/2022.08.22.22279052.
    10.1101/2022.08.22.22279052
  11. Nicholas Cullen; Shorena Janelidze; Erik Stomrud; Sebastian Palmqvist; Wagner Braum; Henrik Zetterberg; Giovanni Frisoni; et al. "Reducing unnecessary tau-PET scans in a memory clinic setting via blood-based biomarker screening". 2022. https://doi.org/10.21203/rs.3.rs-1818516/v1.
    10.21203/rs.3.rs-1818516/v1
  12. Hagberg, Lars; Price, Richard W.; Zetterberg, Henrik; Fuchs, Dietmar; Gisslén, Magnus. "Herpes zoster in HIV-1 infection: the role of CSF pleocytosis in secondary CSF escape and discordance". 2020. https://doi.org/10.1101/2020.01.28.922690.
    10.1101/2020.01.28.922690

Outros

Outra produção
  1. Microstructural associations between locus coeruleus, cortical and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study. 2024. Elise Beckers; Maxime Van Egroo; Nicholas J Ashton; Kaj Blennow; Gilles Vandewalle; Henrik Zetterberg; Benedikt Poser; Heidi Jacobs. https://doi.org/10.1093/cercor/bhae261.
    10.1093/cercor/bhae261
  2. Association between plasma phospho-tau181 and cognitive change from age 73 to 82: Lothian Birth Cohort 1936. 2021. Tyler S. Saunders; Amanda Heslegrave; Declan King; Sarah Harris; Craig Ritchie; Graciela Muniz-Terrera; Ian J. Deary; et al. https://doi.org/10.1101/2021.11.24.469836.
    10.1101/2021.11.24.469836
  3. Amyloid precursor protein localises to ependymal cilia in vertebrates and is required for ciliogenesis and brain development in zebrafish. 2021. Jasmine Chebli; Maryam Rahmati; Tammaryn Lashley; Birgitta Edeman; Anders Oldfors; Henrik Zetterberg; Alexandra Abramsson. https://doi.org/10.1101/2021.06.02.446706.
    10.1101/2021.06.02.446706
  4. Metabolic and muscle-derived serum biomarkers define CHCHD10-linked late-onset spinal muscular atrophy. 2021. Julius Järvilehto; Sandra Harjuhaahto; Edouard Palu; Mari Auranen; Jouni Kvist; Henrik Zetterberg; Johanna Koskivuori; et al. https://doi.org/10.1101/2021.04.07.21254960.
    10.1101/2021.04.07.21254960
  5. 1394 publications according to PubMed and 1642 publications according to Web of Science. Citations: 50,963 (42,642, excluding self-citations); H-index (at age 47) 101 according to Web of Science and 126 according to Google Scholar.. 2021. Zetterberg, Henrik.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2009 - Atual I have been main supervisor for 14 PhD students and assistant supervisor for 28 PhD students who all have defended their thesis. Currently, I am main supervisor for 6 PhD students and assistant supervisor for 27 PhD students. I also supervise several post-docs.
Orientador

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2006 - Atual Senior consultant in Clinical Chemistry Sahlgrenska Universitetsjukhuset Högsbo sjukhus, Suécia

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2017 - Atual Chair of the Scientific Advisory Board for the Swedish Alzheimer Foundation
Presidente / Vice-presidente
Swedish Alzheimer Foundation , Suécia
2017 - Atual Chair of the Scientific Advisory Board for the Kurt and Ingrid Dahrén Foundation Kurt and Ingrid Dahrén Foundation , Suécia
2017 - Atual Vice chair of the Alzheimer’s Association Biofluid-Based Biomarker Professional Interest Area
2017 - Atual Member of the Clinical Chemistry Operations Management Board at Sahlgrenska University Hospital
Membro
Sahlgrenska Universitetsjukhuset Högsbo sjukhus, Suécia
2015 - Atual Member of the International Federation of Clinical Chemistry and Laboratory Medicine Working Group on CSF Proteins
Membro
International Federation of Clinical Chemistry and Laboratory Medicine, Itália
2015 - Atual Co-chair of the Alzheimer’s Association Global Biomarker Standardization Committee
2014 - Atual Global coordinating principal investigator of the Michael J Fox Foundation Assay LEAPS project
Coordenador
Michael J Fox Foundation for Parkinson's Research, Estados Unidos
2012 - Atual Chair of the Scientific Advisory Board for the Greta Johansson and Brita Andersson Foundation for Psychiatric Research
Outro
Stiftelsen Systrarna Greta Johanssons Och Brita Anderssons Minnesfond, Suécia
2015 - 2017 Chair of the Swedish Research Council Neurology panel The Swedish Research Council, Suécia
2015 - 2017 Member of the Scientific Advisory Board for the Swedish Alzheimer Foundation
Membro
Swedish Alzheimer Foundation , Suécia
2014 - 2017 Member of the Alzheimer’s Association Scientific Program Committee
Membro

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2017 - Atual Editor, Molecular and Cellular Neuroscience
2017 - Atual Editor, Scandinavian Journal of Clinical and Laboratory Investigation
2017 - Atual Co-editor, Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
2014 - Atual Associate editor, Alzheimer’s & Dementia
2004 - Atual Reviewer for many journals and grant agencies
Distinções

Prémio

2015 The Parkinson Research Foundation Research Award
The Parkinson Research Foundation , Estados Unidos
2014 The Alzheimer Foundation Grand Research Award
The Alzheimer Foundation , Estados Unidos
2012 Inga Sandeborg Prize
Svenska Lakaresallskapet, Suécia
2012 Third prize in the Astrup Prize Competition at the XXXIII Nordic Congress in Clinical Chemistry in Reykjavik, Iceland
XXIII Nordic Congress in Clinical Chemistry, Islândia
2011 Eric K. Fernström Prize
Eric K. Fernström' Foundation, Suécia

Título

2021 The top-rated expert in Alzheimer Disease in the world during the years 2010-2021, according to Expertscape (https://expertscape.com/ex/alzheimer%20disease).
EXPERTIS, França
2020 Elected member of the Royal Society of Arts and Sciences in Gothenburg
Kungliga Vetenskaps- och Vitterhets-Samhället i Göteborg, Suécia
2012 Honorary Lecturer
Göteborgs universitet Sahlgrenska Akademin, Suécia
2012 Best teacher of the year
Göteborgs universitet Sahlgrenska Akademin, Suécia

Outra distinção

2024 Among the top 1% Highly Cited Researchers in the World in Web of Science since 2021.
2016 Honorary Member of the Mölndal-Härryda Dementia Society,
Mölndal-Härryda Dementia , Suécia