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Paulo Rodrigues Santos completed the Degree in Biochemistry in 1992 and Specialization Studies in Cell Biology in 1995, from the Faculty of Science and Technology of the University of Coimbra, and a Course in Biomedicine in 1996 from the Faculty of Medicine - University of Coimbra. He is attending the Doctorate in Health Sciences Program at the Faculty of Medicine - University of Coimbra. He is a Principal Specialist Biomedical Scientist at the Faculty of Medicine - University of Coimbra, Invited Assistant at the Faculty of Medicine - University of Coimbra, Director of the Immunology and Oncology Laboratory of the Center for Neurosciences and Cellular Biology at the University of Coimbra. He developed his work on Immunogenetics under the supervision of Professor Gottfried Mauff at Institute for Medical Microbiology and Hygiene, Faculty of Medicine, University of Cologne, Germany. He worked on Transplantation Immunobiology as Head of the Functional Genomics Laboratory at the Center for Histocompatibility of the Centre (Coimbra, Portugal). He was Chair of the Education Committee of the European Federation for Immunogenetics (EFI), Board Member of the European Complement Network (ECN) and Vice-President of the Portuguese Society for Immunology (SPI). He is Founder and Coordinator of the Portuguese Group for Immuno-Oncology (gpI-O), a joint working group of the Portuguese Society for Oncology (SPO) and the Portuguese Society for Immunology (SPI). He has published 107 articles in specialized journals. He has 2 book chapter(s) and 1 book(s). He works in the area of Medical and Health Sciences with an emphasis on Immunology. In his professional activities, he interacted with 583 collaborator(s) in co-authorship of scientific works.
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Identificação

Identificação pessoal

Nome completo
Paulo Jorge Ferreira Rodrigues dos Santos

Nomes de citação

  • Rodrigues Santos, Paulo
  • Paulo Santos

Identificadores de autor

Ciência ID
4311-1E7F-9AA8
ORCID iD
0000-0001-7519-1620
Google Scholar ID
69Ca0mkAAAAJ
Researcher Id
M-3175-2013
Scopus Author Id
37021720200

Endereços de correio eletrónico

  • paulo.santos@fmed.uc.pt (Profissional)
  • prsantos@cnc.uc.pt (Profissional)

Telefones

Telefone
  • (+351) 239857777 Ext.: 242844 (Profissional)
Telemóvel
  • (351) 934894068 (Pessoal)

Moradas

  • Insituto de Imunologia, Faculdade de Medicina da Universidade de Coimbra, Polo I, Rua Larga, 3004-504, Coimbra, Coimbra, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia
  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia
  • Ciências Médicas e da Saúde - Medicina Clínica - Oncologia
  • Ciências Médicas e da Saúde - Medicina Clínica - Transplantes

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano Utilizador independente (B2) Utilizador independente (B2) Utilizador elementar (A2) Utilizador independente (B2) Utilizador elementar (A2)
Italiano Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A2) Utilizador independente (B1) Utilizador elementar (A2)
Alemão Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2016 - 2024
Em curso
 Ciências da Saúde (Doutoramento)
Especialização em Imunologia
Universidade de Coimbra Faculdade de Medicina, Portugal
"Immunobiology of Natural Killer Cells: Chronic Myeloid Leukemia as a model in Human Pathophysiology" (TESE/DISSERTAÇÃO)
1996
Concluído
 Biomedicina (Pós-Graduação)
Universidade de Coimbra - Faculdade de Medicina, Portugal
 17
1995
Concluído
 Biologia Celular (Curso de mestrado (conclusão do curso de especialização))
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1992
Concluído
 Bioquímica (Licenciatura)
Especialização em Não Aplicável
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1985
Concluído
 Análises Clínicas e de Saúde Pública (Bacharelato)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
 17
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2009/06/01 - Atual Investigador (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
(...)

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2015/09/01 - Atual Assistente Convidado (Docente Universitário) Universidade de Coimbra - Faculdade de Medicina, Portugal
Universidade de Coimbra - Faculdade de Medicina - Instituto de Imunologia, Portugal
1996/01/01 - 2007/08/31 Professor Adjunto Convidado (Docente Ensino Superior Politécnico) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2009/11/01 - Atual Técnico Especialista de 1ª Classe (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Universidade de Coimbra - Faculdade de Medicina, Portugal
Universidade de Coimbra - Faculdade de Medicina, Portugal
1997 - 2009 Técnico Especialista (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
1994 - 1997 Técnico Principal (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
1991 - 1994 Técnico de 1ª Classe (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
1986 - 1991/10/31 Técnico de 2ª Classe (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
Ministério da Saúde - Centro de Histocompatibilidade do Centro, Portugal
1985 - 1986 Técnico de 2ª Classe (Técnico de Diagnóstico e Terapêutica - Técnico de Análises Clínicas e de Saúde Pública) Ministério da Saúde - Hospital Distrital do Fundão, Portugal
Ministério da Saúde - Hospital Distrital do Fundão, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/09/01 - Atual Head of Research and Science Communication Universidade de Coimbra - Faculdade de Medicina - Instituto de Imunologia, Portugal
Universidade de Coimbra - Faculdade de Medicina - Instituto de Imunologia, Portugal
2009/06/01 - Atual Dirigente de laboratório, instituto, museu, centro ou observatório Universidade de Coimbra - Centro de Neurociências e Biologia Celular - Laboratório de Imunologia e Oncologia, Portugal
Universidade de Coimbra - Centro de Neurociências e Biologia Celular - Laboratório de Imunologia e Oncologia, Portugal
2001/12/01 - 2009/05/31 Dirigente de laboratório, instituto, museu, centro ou observatório Ministério da Saúde - Centro de Histocompatibilidade do Centro - Laboratório de Genómica Funcional, Portugal
Ministério da Saúde - Centro de Histocompatibilidade do Centro - Laboratório de Genómica Funcional, Portugal
Projetos

Bolsa

Designação Financiadores
2024/01/01 - Atual IN8COLON: Single-cell metabolic reprogramming of innate lymphoid cells in patients with colorectal cancer
NRC.LPCC/CIMAGO 2023
Universidade de Coimbra Faculdade de Medicina, Portugal
 Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
Em curso
2022 - Atual COMP-S: Cultivating Compassionate Schools: The effects of an evidence-based compassionate mind training program for teachers on psychophysiological and epigenetic correlates of wellbeing, prosociality and stress
PT/FB/BL-2022-074
Investigador
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Fundação Bial
Em curso
2019 - Atual MirAE: Immunological side effects of treatment with “checkpoint inhibitors” – immunological phenotypes and biomarkers
PEPITA2019/BST/FMUC/MirAE
Investigador
Universidade de Coimbra - Faculdade de Medicina, Portugal
 Banco Santander Portugal
Em curso
2023 - 2025 LUCA-IMMUNEXT: Immunogenomic profiles associated with therapy with immune checkpoint inhibitors in stages IIIb and IV of non-small cell lung cancer
LUCA-IMMUNEXT
Investigador responsável
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Grupo de Estudos do Cancro do Pulmão (GECP)
Em curso

Projeto

Designação Financiadores
2021 - Atual Helicobacter pylori eradication therapy in Portugal: prospective, randomized, blind and multicentre trial on the efficacy of quadruple therapies and their clinical impact and immunological, oral and gut microbiota changes
PTDC/MEC-GAS/7361/2020
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023 - 2025 Deciphering the role of Piezo1 mechanosensitive channel in microglia-mediated glaucomatous neurodegeneration
2022.01354.PTDC
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023 - 2025 The Hippo Ndr kinases roles in inflammation and neovascularization in diabetic retinopathy
2022.06170.PTDC
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2023 - 2025 IN8COLON: Single-cell metabolic reprogramming of Innate Lymphoid Cells in Colorectal Carcinoma patients
NRC.LPCC/CIMAGO/IN8COLON
Co-Investigador Responsável (Co-IR)
Liga Portuguesa Contra o Cancro
2022 - 2025 Epi-UNCOV - Unravelling how unconventional T cells are regulated by micronutrients and its role in epithelial malignancy
2022.06145.PTDC
Investigador
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2022 - 2025 Kinder-GUT - Role of diet-derived retinoids in CD8aa intraepithelial lymphocytes and intestinal defence at early-life
HR22-00754
Investigador
Universidade de Coimbra, Portugal
 Fundació Caixa d' Estalvis de Catalunya
Em curso
2018/07/26 - 2022/07/25 Exercício físico e depressão: efeito antidepressivo dos exersomas
PTDC/SAU-DES/30786/2017
Investigador
Universidade de Coimbra, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/02/01 - 2022/01/31 IMMUNYON: Immune Monitoring of Trabectedin (Yondelis®) Therapy In Refractory Soft Tissue Sarcoma Patients
IMMUNYON-CIMAGO12/18
Investigador responsável
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
 PharmaMar SA
Em curso
2017/04/01 - 2019/06/30 Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions
ProSafe/0001/2016
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2014/01/01 - 2015/12/31 STEPPING ON THE RAGE NETWORK: PHYSICAL EXERCISE IN THE MANAGEMENT OF PARKINSON´S DISEASE
EXPL/DTP-DES/0104/2013
Investigador
CNC.IBILI, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/03 - 2014/07/01 CROSS-TALK BETWEEN CHRONIC RENAL FAILURE, INFLAMMATION AND ERYTHROPOIESIS IN RESISTANCE TO RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY
PTDC/SAU-TOX/114253/2009
Investigador
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2012/12/31 Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/01/01 - 2008/09/30 INFLUENCE OF TRANSPLANT PRESERVATION SOLUTIONS IN CARDIAC METABOLIC AND IMMUNOLOGICAL PROFILES
POCI/SAU-OBS/55802/2004
Investigador
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/09 - 2008/08 NEO-NEUROGENESIS AND MICROGLIA IN TEMPORAL LOBE EPILESY: ROLE OF PRO-INFLAMMATORY CYTOKINES AND NEUROPEPTIDE Y IN NEUROPROTECTION OF NEW NEURONS
POCI/SAU-NEU/58492/2004
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2003/01 - 2008/01 Cr(VI)-INDUCED GENOTOXIC STRESS: THE SIGNALLING MECHANISMS THAT LINK CELL CYCLE AND CELL FATE
POCTI/CBO/48631/2002
Investigador
Fundação para a Ciência e a Tecnologia, Portugal
 Universidade de Coimbra
Concluído
Produções

Publicações

Artigo em revista
  1. Gonçalves, Milene; Furgiuele, Alessia; Rasini, Emanuela; Legnaro, Massimiliano; Ferrari, Marco; Luini, Alessandra; Rodrigues-Santos, Paulo; et al. "A peripheral blood mononuclear cell-based in vitro model: A tool to explore indoleamine 2, 3-dioxygenase-1 (IDO1)". European Journal of Pharmacology 968 (2024): 176420. http://dx.doi.org/10.1016/j.ejphar.2024.176420.
    10.1016/j.ejphar.2024.176420
  2. Jani-Sofia Almeida; José Manuel Casanova; Manuel Santos-Rosa; Raquel Tarazona; Rafael Solana; Paulo Rodrigues-Santos. "Natural Killer T-like Cells: Immunobiology and Role in Disease". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24032743.
    10.3390/ijms24032743
  3. Masin PS; Vicentin, HA; Elpidio, LN; Sell, AM; Visentainer, L; De Lima Neto, QA; Zacarias, JM; et al. "Genetic polymorphisms of Toll-like receptors in leprosy patients from Southern Brazil". Front Genet (2022): https://www.frontiersin.org/articles/10.3389/fgene.2022.952219.
    Acesso aberto • Aceite para publicação
  4. Joana Delgado-Silva; Paulo Rodrigues-Santos; Jani-Sofia Almeida; Manuel Santos-Rosa; Lino Gonçalves. "Dynamics of Soluble Factors and Double-Negative T Cells Associated with Response to Renal Denervation in Resistant Hypertension Patients". Journal of Personalized Medicine (2022): https://doi.org/10.3390/jpm12030343.
    10.3390/jpm12030343
  5. José Manuel Casanova; Jani-Sofia Almeida; John David Reith; Luana Madalena Sousa; Ruben Fonseca; Paulo Freitas-Tavares; Manuel Santos-Rosa; Paulo Rodrigues-Santos. "Tumor-Infiltrating Lymphocytes and Cancer Markers in Osteosarcoma: Influence on Patient Survival". Cancers (2021): https://doi.org/10.3390/cancers13236075.
    10.3390/cancers13236075
  6. Luana Madalena Sousa; Jani Sofia Almeida; Tânia Fortes-Andrade; Manuel Santos-Rosa; Paulo Freitas-Tavares; José Manuel Casanova; Paulo Rodrigues-Santos. "Tumor and Peripheral Immune Status in Soft Tissue Sarcoma: Implications for Immunotherapy". Cancers 13 15 (2021): 3885-3885. https://doi.org/10.3390/cancers13153885.
    10.3390/cancers13153885
  7. Tânia Fortes-Andrade; Jani Sofia Almeida; Luana Madalena Sousa; Manuel Santos-Rosa; Paulo Freitas-Tavares; José Manuel Casanova; Paulo Rodrigues-Santos. "The Role of Natural Killer Cells in Soft Tissue Sarcoma: Prospects for Immunotherapy". Cancers 13 15 (2021): 3865-3865. https://doi.org/10.3390/cancers13153865.
    10.3390/cancers13153865
  8. Mafalda Campeão; Luciana Fernandes; Inês R. Pita; Cristina Lemos; Syed F. Ali; Félix Carvalho; Paulo Rodrigues-Santos; et al. "Acute MDPV Binge Paradigm on Mice Emotional Behavior and Glial Signature". Pharmaceuticals (2021): https://www.mdpi.com/1424-8247/14/3/271.
    10.3390/ph14030271
  9. Mendes, João; Areia, Ana Luísa; Rodrigues-Santos, Paulo; Santos-Rosa, Manuel; Mota-Pinto, Anabela. "Innate Lymphoid Cells in Human Pregnancy". Frontiers in Immunology 11 (2020): http://dx.doi.org/10.3389/fimmu.2020.551707.
    10.3389/fimmu.2020.551707
  10. Delgado Silva, Joana; Almeida, Jani-Sofia; Rodrigues-Santos, Paulo; Santos Rosa, Manuel; Gonçalves, Lino. "Activated double-negative T cells (CD3+CD4-CD8-HLA-DR+) define response to renal denervation for resistant hypertension". Clinical Immunology 218 (2020): 108521. http://dx.doi.org/10.1016/j.clim.2020.108521.
    10.1016/j.clim.2020.108521
  11. S. Lobo, Ana Catarina; Gomes-da-Silva, Lígia C.; Rodrigues-Santos, Paulo; Cabrita, António; Santos-Rosa, Manuel; Arnaut, Luís G.. "Immune Responses after Vascular Photodynamic Therapy with Redaporfin". Journal of Clinical Medicine 9 1 (2019): 104. http://dx.doi.org/10.3390/jcm9010104.
    10.3390/jcm9010104
  12. Almeida, Jani-Sofia; Couceiro, Patrícia; López-Sejas, Nelson; Alves, Vera; Ružicková, Lenka; Tarazona, Raquel; Solana, Rafael; et al. "NKT-Like (CD3+CD56+) Cells in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors". Frontiers in Immunology 10 (2019): http://dx.doi.org/10.3389/fimmu.2019.02493.
    10.3389/fimmu.2019.02493
  13. Rodrigues-Santos, Paulo; López-Sejas, Nelson; Almeida, Jani Sofia; Ruzicková, Lenka; Couceiro, Patricia; Alves, Vera; Campos, Carmen; et al. "Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors". (2018):
    10.3389/fimmu.2018.02587
  14. Bento, Daniela; Almeida, Jani Sofia; Couceiro, Patricia; Alves, Vera; Santos-Rosa, Manuel; Barata, Fernando Jose; Rodrigues-Santos, Paulo; Ferreira Rodrigues Figueiredo, Ana Maria. "MONITORING IMMUNODYNAMICS IN IMMUNE CHECKPOINT INHIBITOR THERAPY FOR STAGE IIIB/IV NON-SMALL CELL LUNG CANCER". European Respiratory Journal 52 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000455567102331&KeyUID=WOS:000455567102331.
    10.1183/13993003.congress-2018.PA2226
  15. Miranda, Catarina Oliveira; Marcelo, Adriana; Silva, Teresa Pereira; Barata, Joao; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nobrega, Clevio; et al. "Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease". Molecular Therapy 26 9 (2018): 2131-2151. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000447756800008&KeyUID=WOS:000447756800008.
    10.1016/j.ymthe.2018.07.007
  16. Viana, Sofia D.; Pita, Ines R.; Lemos, Cristina; Rial, Daniel; Couceiro, Patricia; Rodrigues-Santos, Paulo; Caramelo, Francisco; et al. "The effects of physical exercise on nonmotor symptoms and on neuroimmune RAGE network in experimental parkinsonism". Journal of Applied Physiology 123 1 (2017): 161-171. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000409453700003&KeyUID=WOS:000409453700003.
    10.1152/japplphysiol.01120.2016
  17. Alves, R.; Goncalves, A. C.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, A. M.; Sarmento-Ribeiro, A. B.. "THE ROLE OF MICRORNAS IN CHRONIC MYELOID LEUKEMIA THERAPEUTIC SELECTION". Haematologica 102 (2017): 438-438. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003201&KeyUID=WOS:000404127003201.
  18. Rodrigues-Santos, P.; Almeida, J. S.; Couceiro, P.; Alves, V.; Simplicio, J. R.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M.. "SOLUBLE AND MEMBRANE-BOUND RECEPTOR-LIGAND IMMUNE CHECKPOINTS AND CHRONIC MYELOID LEUKEMIA: CORRELATIONS WITH MOLECULAR RESPONSE AND TYROSINE KINASE INHIBITOR THERAPY". Haematologica 102 (2017): 430-431. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003184&KeyUID=WOS:000404127003184.
  19. Rodrigues Santos, P.; Abranches, P.; Couceiro, P.; Simplicio, J. R.; Almeida, J. S.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M.. "TRANSCRIBED ULTRACONSERVED NONCODING RNAS (T-UCRS) IN CHRONIC MYELOID LEUKEMIA: EXPRESSION PROFILES ASSOCIATED WITH MOLECULAR RESPONSE TO THERAPY WITH TYROSINE KINASE INHIBITORS". Haematologica 102 (2017): 429-430. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003181&KeyUID=WOS:000404127003181.
  20. Mendes, F.; Domingues, C.; Rodrigues-Santos, P.; Abrantes, A.M.; Gonçalves, A.C.; Estrela, J.; Encarnação, J.; et al. "The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation". Biochimica et Biophysica Acta - Reviews on Cancer 1865 2 (2016): 168-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958206655&partnerID=MN8TOARS.
    10.1016/j.bbcan.2016.02.002
  21. Mazini, P.S.; Alves, H.V.; Reis, P.G.; Lopes, A.P.; Sell, A.M.; Santos-Rosa, M.; Visentainer, J.E.L.; Rodrigues-Santos, P.. "Gene association with leprosy: A review of published data". Frontiers in Immunology 6 JAN (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84958211864&partnerID=MN8TOARS.
    10.3389/fimmu.2015.00658
  22. Rego, Â.; Viana, S.D.; Ribeiro, C.A.F.; Rodrigues-Santos, P.; Pereira, F.C.. "Monophosphoryl Lipid-A: A Promising Tool for Alzheimer's Disease Toll". Journal of Alzheimer's Disease 52 4 (2016): 1189-1202. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974530211&partnerID=MN8TOARS.
    10.3233/JAD-151183
  23. Viana, S.D.; Valero, J.; Rodrigues-Santos, P.; Couceiro, P.; Silva, A.M.; Carvalho, F.; Ali, S.F.; Fontes-Ribeiro, C.A.; Pereira, F.C.. "Regulation of striatal astrocytic receptor for advanced glycation end-products variants in an early stage of experimental Parkinson's disease". Journal of Neurochemistry (2016): 598-609. http://www.scopus.com/inward/record.url?eid=2-s2.0-84981172818&partnerID=MN8TOARS.
    10.1111/jnc.13682
  24. Areia, A.; Vale-Pereira, S.; Alves, V.; Rodrigues-Santos, P.; Santos-Rosa, M.; Moura, P.; Mota-Pinto, A.. "Can membrane progesterone receptor a on T regulatory cells explain the ensuing human labour?". Journal of Reproductive Immunology 113 (2016): 22-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960429929&partnerID=MN8TOARS.
    10.1016/j.jri.2015.10.002
  25. Ferreira-Teixeira, M.; Paiva-Oliveira, D.; Parada, B.; Alves, V.; Sousa, V.; Chijioke, O.; Münz, C.; et al. "Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells". BMC Medicine 14 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992153376&partnerID=MN8TOARS.
    10.1186/s12916-016-0715-2
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  77. Almeida, A.; Rodrigues, C.; Cabrita, A.; Alves, R.; Santos, P.. "Renal inflammation after lower limbs ischemia-reperfusion syndrome". Tissue Antigens 71 4 (2008): 344-344. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000254629500212&KeyUID=WOS:000254629500212.
  78. Teles, A.; Rasteiro, C.; Almeida, A.; Balseiro, S.; Sampaio, A.; Paiva, A.; Santos, P.. "Role of IL-12, IFN-gamma and their receptors expressed by monocytes and T cells in multiple sclerosis patients". Tissue Antigens 71 4 (2008): 339-339. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000254629500198&KeyUID=WOS:000254629500198.
  79. Rafael, A.; Almeida, A.; Santos, P.; Cabrita, A. S.; Alpoim, M. C.. "A comparative study for different period of time of administration of Cr(VI) in the drinking water and its effects in liver of Wistar rats". Toxicology Letters 172 (2007): S216-S216.
    10.1016/j.toxlet.2007.05.544
  80. Rafael, A. L.; Almeida, A.; Santos, P.; Parreira, I.; Madeira, V. M. S.; Alves, R.; Cabrita, A. M. S.; Alpoim, M. C.. "A role for transforming growth factor-beta apoptotic signaling pathway in liver injury induced by ingestion of water contaminated with high levels of Cr(VI)". Toxicology and Applied Pharmacology 224 2 (2007): 163-173.
    10.1016/j.taap.2007.07.004
  81. Almeida, A.; Alves, R.; Cabrita, A.; Santos, P.. "Vitamin D immunossupressant effect on II-10 and MCP-1 during infection". Tissue Antigens 69 5 (2007): 436-436. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000167&KeyUID=WOS:000245985000167.
  82. Alves, R.; Almeida, A.; Santos, P.; Cabrita, A.. "Angiotensin II gene receptor expression in unilateral ureteric obstruction". Nephrology Dialysis Transplantation 22 (2007): 110-110. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253320600307&KeyUID=WOS:000253320600307.
  83. Pinto, S.; Santos, P.; Martinho, A.; Pimentel, P.; Campilho, F.; Pais, M. L.. "KIR repertoire and HLA class I ligands in hematopoietic stemcell transplantation: influence in the development of graft-versus-host disease and relapse of the primary disease after transplant". Tissue Antigens 69 5 (2007): 520-520. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000387&KeyUID=WOS:000245985000387.
  84. Alves, R.; Almeida, A.; Santos, P.; Cabrita, A.. "Sex hormones gene receptors expression in unilateral ureteric obstruction". Nephrology Dialysis Transplantation 22 (2007): 109-110. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253320600305&KeyUID=WOS:000253320600305.
  85. Gala, D.; Almeida, A.; Sampaio, A.; Balseiro, S.; Paiva, A.; Santos, P.. "TNF, TNFR1 and TNFR2 polymorphisms in multiple sclerosis". Tissue Antigens 69 5 (2007): 463-463. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000237&KeyUID=WOS:000245985000237.
  86. Rafael, A.; Almeida, A.; Parreira, I.; Santos, P.; Carvalho, M.; Alves, R.; Cabrita, A. M.; Alpoim, M. C.. "Toxic effects on Wistar rat kidney of lead administrated in water". Toxicology Letters 164 (2006): S202-S203.
    10.1016/j.toxlet.2006.07.078
  87. Rafael, A.; Almeida, A.; Parreira, I.; Santos, P.; Carvalho, M.; Cabrita, A. M.; Alpoim, M. C.. "Toxic effects of Cr(VI) in liver after administration in the drinking water to Wistar rats". Toxicology Letters 164 (2006): S202-S202.
    10.1016/j.toxlet.2006.07.077
  88. Saavedra, A.; Baltazar, G.; Santos, P.; Carvalho, C. M.; Duarte, E. P.. "Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: Role of neuron-glia crosstalk". Neurobiology of Disease 23 3 (2006): 533-542.
    10.1016/j.nbd.2006.04.008
  89. Almeida, A.; Cabrita, A.; Alves, R.; Santos, P.. "Androgen receptor gene expression associated with susceptibility to renal disease progression". Tissue Antigens 67 6 (2006): 499-500. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600156&KeyUID=WOS:000237949600156.
  90. Santos, P.; Balseiro, S.; Almeida, A.; Domingos, A.; Segorbe-Luis, A.. "Cytokine gene polymorphisms and progression of Mycobacterium tuberculosis infected individuals to pulmonary disease". Tissue Antigens 67 6 (2006): 535-535. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600245&KeyUID=WOS:000237949600245.
  91. Alves, R.; Almeida, A.; Santos, P.; Cabrita, A.. "Sirolimus and the extracellular matrix turnover in experimental hydronephrosis". Nephrology Dialysis Transplantation 21 (2006): 37-37. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000239919000097&KeyUID=WOS:000239919000097.
  92. Alves, R.; Almeida, A.; Santos, P.; Cabrita, A.. "Sirolimus and the interleukins gene expression in experimental hydronephrosis". Nephrology Dialysis Transplantation 21 (2006): 305-305. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000239919002114&KeyUID=WOS:000239919002114.
  93. Santos, P.; Balseiro, S.; Almeida, A.; Mayunga, R.; Segorbe-Luis, A.. "Cytokine gene polymorphisms in lepromatous leprosy patients from Angola". Tissue Antigens 67 6 (2006): 545-545. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600272&KeyUID=WOS:000237949600272.
  94. Almeida, A.; Cabrita, A.; Alves, R.; Santos, P.. "Early effects of sirolimus on cytokine gene expression in an experimental animal model of hydronephrosis: females precede males in downregulation". Tissue Antigens 67 6 (2006): 508-509. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600180&KeyUID=WOS:000237949600180.
  95. Santos, P.; Balseiro, S.; Almeida, A.; Domingos, A.; Segorbe-Luis, A.. "Toll-like receptors polymorphisms and Mycobacterium tuberculosis: from infection to pulmonary disease". Tissue Antigens 67 6 (2006): 527-528. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600226&KeyUID=WOS:000237949600226.
  96. Dionisio, A. M.; Balseiro, S.; Almeida, A.; Mayunga, R.; Segorbe-Luis, A.; Santos, P.. "Toll-like receptors polymorphisms in lepromatous leprosy patients from Angola". Tissue Antigens 67 6 (2006): 530-530. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600232&KeyUID=WOS:000237949600232.
  97. Geraldes, C.; Goncalves, A. C.; Santos, P.; Tavares, P.; Teixeira, A.. "BCR-ABL fusion gene and BCR-ABL transcript - Correlation with response to therapy in Chronic Myeloid Leukaemia". Blood 106 11 (2005): 297B-297B. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000233426101570&KeyUID=WOS:000233426101570.
  98. Rafael, A. I.; Parreira, I.; Carvalho, M. T.; Santos, P.; Alpoim, C.; Cabrita, A. M. S.. "Heart proliferation and apoptosis markers in experimental lead intoxication". Faseb Journal 19 4 (2005): A489-A490. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227610703335&KeyUID=WOS:000227610703335.
  99. Carvalho, M. T.; Parreira, I.; Rafael, A.; Almeida, A.; Santos, P.; Alpuim, C.; Cabrita, A. S.. "Liver proliferation and apoptosis markers in experimental chromium intoxication". Faseb Journal 19 4 (2005): A311-A311. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227610702153&KeyUID=WOS:000227610702153.
  100. Santos, P.; Morgado, J. M.; Pratas, R.; Figueiredo, C.; Crespo, I.; Laranjeira, P.; Freitas, A.; et al. "IL1-beta IL-6 IL12, TNF-alpha and TNF-beta produced by peripheral blood monocytes and subsets of dendritic cells in multidrug-resistant pulmonary tuberculosis". Genes and Immunity 5 (2004): S73-S73. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900290&KeyUID=WOS:000221955900290.
  101. Santos, P.; Lopes, J.; Gomes, J. M.; Pereira, L.; Freitas, A.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A.. "Mannan-binding lectin (MBL) polymorphisms and protein levels in pulmonary tuberculosis". Genes and Immunity 5 (2004): S39-S39. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900155&KeyUID=WOS:000221955900155.
  102. Santos, P.; Almeida, A.; Lopes, J.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A.. "Gene expression profile of co-stimulatory receptors, chemokines and cytokines using real-time PCR analysis in multidrug-resistant tuberculosis". Genes and Immunity 5 (2004): S71-S71. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900283&KeyUID=WOS:000221955900283.
  103. Santos, P.; Lopes, J.; Gomes, J. M.; Pereira, L.; Freitas, A.; Paiva, A.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A.. "Mannan-binding lectin (MBL) deficiency and protection of Mycobacterium tuberculosis infected individuals from progression to pulmonary disease". Molecular Immunology 40 2-4 (2003): 208-208. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000184975900092&KeyUID=WOS:000184975900092.
  104. Santos, P.; Balseiro, S.; Ballesteros, R.; Mareco, R.; Vale-Pereira, S.; Paiva, A.; Martinho, A.; et al. "IL-1 alpha, IL-1 beta, IL-1R, IL-1RA, IL4-RA, IL-12, IFN-gamma, TGF-beta, TNF-alpha, IL-2, IL-4, IL-6 and IL-10 gene polymorphism in rejection and infection after liver transplantation". Genes and Immunity 4 (2003): S55-S55. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000183208800216&KeyUID=WOS:000183208800216.
  105. Caetano, J.; Martinho, A.; Freitas, A.; Paiva, A.; Silva, I.; Simoes, O.; Santos, P.; et al. "Lineage-specific chimerism monitoring after allogeneic hematopoietic stem cell transplantation". Bone Marrow Transplantation 31 (2003): S143-S144. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000181969200433&KeyUID=WOS:000181969200433.
  106. Bruges-Armas J; Lima C; Peixoto MJ; Santos P; Mendonça D; da Silva BM; Herrero-Beaumont G; Calin A. "Prevalence of spondyloarthritis in Terceira, Azores: a population based study.". (2002): http://europepmc.org/abstract/med/12006333.
    10.1136/ard.61.6.551
  107. Lemos MC; Carrilho F; Rodrigues FJ; Santos P; Carvalheiro M; Ruas MA; Regateiro FJ. "Early onset of medullary thyroid carcinoma in a kindred with multiple endocrine neoplasia type iia associated with cutaneous lichen amyloidosis.". (2002): http://europepmc.org/abstract/med/11939755.
  108. Alvarez, M.; Martinho, A.; Simoes, O.; Regateiro, F. R.; Abade, A.; Santos, P.. "Molecular typing for HLA-G and HLA-E using ARMS-PCR". Tissue Antigens 59 (2002): 80-80. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000176311300260&KeyUID=WOS:000176311300260.
  109. Balseiro, S.; Reuter, S.; Simoes, O.; Martinho, A.; Paiva, A.; Mateus, M. R.; Solva, I.; et al. "Screening for HLA class I expression variants in a Portuguese caucasoid population". Tissue Antigens 59 (2002): 79-79. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000176311300257&KeyUID=WOS:000176311300257.
  110. Alvarez, M.; Santos, P.; Martinho, A.; Simoes, O.; Abade, A.; Breda-Coimbra, H.. "HLA-G genetic polymorphism in 57 Portuguese white families studied by PCR-RFLP and PCR-SSOP". Transplantation Proceedings 31 4 (1999): 1829-1831.
    10.1016/s0041-1345(99)00179-7
  111. Paiva, A.; Freitas, A.; Loureiro, A.; Couceiro, A.; Martinho, A.; Simoes, O.; Santos, P.; et al. "Functional aspects of cord blood lymphocytes response to polyclonal and allogeneic activation". Bone Marrow Transplantation 22 (1998): S31-S34. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000075190200014&KeyUID=WOS:000075190200014.
  112. ArnaizVillena, A.; MartinezLaso, J.; GomezCasado, E.; DiazCampos, N.; Santos, P.; Martinho, A.; BredaCoimbra, H.. "Relatedness among Basques, Portuguese, Spaniards, and Algerians studied by HLA allelic frequencies and haplotypes". Immunogenetics 47 1 (1997): 37-43.
    10.1007/s002510050324
  113. Carvalheiro, M.; Martinho, A.; Humbel, R. L.; Fagulha, I.; Gomes, L.; Fagulha, A.; Paiva, S.; et al. "HLA-DR/DQ-haplotypes and autoantibodies in Portuguese gestational diabetic women". Diabetologia 40 (1997): 871-871. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997XG12300865&KeyUID=WOS:A1997XG12300865.
  114. Plum, G.; Brenden, M.; Santos, P.; Schwarz, E.; Wahnschaffe, U.; Mauff, G.; Pulverer, G.. "Serum antibody reactivity to recombinant mig and whole cell antigens in Mycobacterium avium infection". Zentralblatt Fur Bakteriologie-International Journal of Medical Microbiology Virology Parasitology and Infectious Diseases 284 2-3 (1996): 348-360. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UY06600020&KeyUID=WOS:A1996UY06600020.
  115. Martinho, A.; TodoBom, A.; Cortesao, M. J.; Leitao, T.; Pereira, C.; Santos, P.; Simoes, O.; et al. "Distribution of HLA-DR and DQ alleles in allergic patients to Parietaria lusitanica". Human Immunology 47 1-2 (1996): P865-P865. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UM45500865&KeyUID=WOS:A1996UM45500865.
  116. Santos, P.; Martinho, A.; Fonseca, A. M.; Simoes, O.; Ferreira, R. V.; Mateus, M. R.; Ferreira, A. M.; et al. "HLA-A*02 subtyping in a Portuguese population". Human Immunology 47 1-2 (1996): P14-P14. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UM45500017&KeyUID=WOS:A1996UM45500017.
Capítulo de livro
  1. Rafael, A. I.; Almeida, A.; Parreira, I.; Santos, P.; Cabrita, A. M.; Alpoim, M. C.. "An in vivo study on the effects of hexavalent chromium contaminated drinking water on rat livers". editado por Alpoim, M. C.; Morais, P. V., 315-318. 2006.
  2. Anjos, M. J.; Souto, L.; Carvalho, M.; Martinho, A.; Santos, P.; Simoes, O.; Breda-Coimbra, H.; Vieira, D. N.; Vide, M. C.. "Forensic view for genetic profiles after bone marrow transplants". editado por Olaisen, B.; Brinkmann, B.; Lincoln, P. J., 156-158. 1998.
Livro
  1. Teixeira-Lemos, E.; Teixeira, H.M.; Piloto, N.; Teixeira, M.; Parada, B.; Rodrigues-Santos, P.; Carvalho, L.; et al. Cardiometabolic injury due to recombinant human erythropoietin doping for improvement of sports performance: Chronic (training) versus acute (extenuating) aerobic exercise. 2012.
Atividades

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/09/01 - 2024/07/31 Innate Lymphoid Cells in Triple Negative Breast Cancer: From Cancer Immunobiology to Immunotherapy
Orientador
 Master in Biomedical Research (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2022 - 2023 Differential immune-related expressed genes in Soft Tissue Sarcoma patients
Orientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra - Centro de Neurociências e Biologia Celular - Laboratório de Imunologia e Oncologia, Portugal
2022 - 2023 Expression profile of immune-related genes in Non-Small Cell Lung Cancer patients
Orientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra - Centro de Neurociências e Biologia Celular - Laboratório de Imunologia e Oncologia, Portugal
2022 - 2023 Immune-related gene expression in Soft Tissue Sarcoma: trabectedin vs anthracycline-based therapy
Orientador
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra - Centro de Neurociências e Biologia Celular - Laboratório de Imunologia e Oncologia, Portugal
2020/09/01 - 2021/07/30 Immune monitoring of Soft Tissue Sarcoma therapy
Orientador de Luana Madalena Oliveira da Silva de Sousa
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/09/01 - 2021/07/30 Comprehensive analysis of Natural Killer cell subsets in Soft Tissue Sarcoma
Orientador de Tânia Clarete Fortes Andrade
 Investigação Biomédica (Mestrado)
Universidade de Coimbra - Faculdade de Medicina, Portugal
2021 - 2021 Peripheral immune status of trabectedin versus anthracycline-based chemotherapy in Soft Tissue Sarcoma
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2021 Effect of dopaminergic agents on CD96, TIGIT and CD226 in Natural Killer cells
Orientador
 Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - 2020 Immune monitoring of Trabectedin (Yondelis®) therapy in Soft Tissue Sarcoma patients
Orientador
 Medicina (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2018 OPTIMIZAÇÃO DO DIÁLOGO ENTRE CÉLULAS NATURAL KILLER E CÉLULAS DENDRÍTICAS PARA APLICAÇÃO EM IMUNOTERAPIA CELULAR ADOPTIVA EM ONCOLOGIA
Orientador
 Patologia Experimental (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2018 Monitorização Imunológica da Terapia com Inibidores dos Checkpoints Imunológicos em pacientes com Cancro do Pulmão
Orientador
 Medicina (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - 2017 CD96 (TACTILE), CD226 (DNAM-1) and TIGIT in the regulation of immune functions in chronic myeloid leukemia
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - 2017 PD-1 signaling in Natural Killer cells and Chronic Myeloid Leukemia therapy.
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - 2017 Exosomes and natural killer cells: potential for biomedical applications.
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015 Adoptive cell transfer for immunotherapy in solid tumors: activation and expansions of natural killer cells for eradication of malignant cells
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015 Resposta Imunológica em insuficientes renais crónicos sujeitos a diálise peritoneal
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014 Immunobiology of Natural Killer Cells: Subpopulations,phenotypes and functional properties useful for immunotherapy
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014 Characterization of Natural Killer Cells in Chronic Myeloid Leukemia Patients
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023 - Atual Fundamentos da Ciência Investigação Biomédica (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - Atual Métodos e Técnicas de Investigação Ciências da Saúde (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2017/09/01 - Atual Imunologia I Mestrado Integrado em Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2017/09/01 - Atual Imunologia II mestrado Integrado em medicina (Mestrado integrado) Universidade de Coimbra - Faculdade de Medicina, Portugal
2011/09/01 - 2017 Imunologia Mestrado Integrado de Medicina (Mestrado integrado) Universidade de Coimbra - Faculdade de Medicina, Portugal
1996 - 2007 Biologia Molecular Análises Clínicas e de Saúde Pública (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
1996 - 2007 Metodologia da Investigação Científica Análises Clínicas e de Saúde Pública Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
1996 - 2007 Investigação Aplicada Análises Clínicas e de Saúde Pública (Licenciatura) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal

Membro de associação

Nome da associação Tipo de participação
2022 - Atual Sociedade Portuguesa de Oncologia (SPO) Member
2022 - Atual Grupo de Estudos do Cancro do Pulmão (GECP) Member
2022 - Atual European Society for Medical Oncology (ESMO) Member
1988 - Atual Sociedade Portuguesa de Imunologia (SPI) Member
1988 - Atual Sociedade Portuguesa de Pneumologia (SPP) Member

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2017 - Atual Grupo Português de Imuno-Oncologia (GPI-O)
Coordenador
 Sociedade Portuguesa de Imunologia, Portugal

Sociedade Portuguesa de Oncologia (SPO), Portugal
2006 - 2012 Sociedade Portuguesa de Imunologia (SPI)
Presidente / Vice-presidente
 Sociedade Portuguesa de Imunologia, Portugal
2003 - 2009 European Complement Network (ECN)
Diretor
 European Complement Network (ECN) , Países Baixos
2005 - 2008 European Federation of Immunogenetics (EFI)
Presidente / Vice-presidente
 European Federation of Immunogenetics, Países Baixos
2005 - 2007 Revista Portuguesa de Ciências Biomédicas (RPCB)
Diretor
 Revista Portuguesa de Ciências Biomédicas (RPCB), Portugal
Distinções

Prémio

2024 Research Award in Biomedical Laboratory Sciences
Associação Portuguesa de Ciências Biomédicas Laboratoriais (BioMedLab), Portugal
2023 Research Award in Oncology (Colorrectal Cancer)
Liga Portuguesa Contra o Cancro, Portugal

Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2023 Research Award in Oncology (Lung Cancer)
Sociedade Portuguesa de Oncologia (SPO), Portugal
2022 Research Award in Oncology (Sarcomas)
Sociedade Portuguesa de Oncologia (SPO), Portugal
2022 Research Award in Oncology (Sarcomas)
Liga Portuguesa Contra o Cancro, Portugal

Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal
2021 Research Award in Hematology (Chronic Myeloid Leukemia)
Sociedade Portuguesa de Hematologia, Portugal
2019 Research Award in Oncology (Genitourinary)
Sociedade Portuguesa de Oncologia (SPO), Portugal
2019 Research Award (Melanoma)
Banco Santander Portugal, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
2018 Prémio MEDES 2018
Fundación Española para la Ciencia y la Tecnología, Espanha

Fundación Lilly, Espanha
2017 SIMO EDUCACION 2017
IFEMA - Feria de Madrid, Espanha
2013 Research Award in Uro-Oncology
Astellas European Foundation, Reino Unido
1999 Research Award in Gastroenterology
Sociedade Portuguesa de Gastrenterologia, Portugal
1998 Research Award in Allergy and Clinical Immunology
Sociedade Portuguesa de Alergologia e Imunologia Clínica, Portugal
1995 Research Award in Allergy and Clinical Immunology
Sociedade Portuguesa de Alergologia e Imunologia Clínica, Portugal
1988 Thomé Villar Research Award
Sociedade Portuguesa de Pneumologia, Portugal