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Vera Constâncio is a laCaixa INPhINIT doctoral fellow (2020), conducting her PhD research in the Cancer Biology and Epigenetics Group at the Portuguese Oncology Institute of Porto and the Systems Oncology Group at the Champalimaud Foundation. She holds a BSc in Biology (2017) from the University of Aveiro and an MSc in Oncology (2019) from the Institute of Biomedical Sciences Abel Salazar, University of Porto. In 2022, she was awarded an FCT exploratory project as Principal Investigator. She also received the Portuguese League Against Cancer & PT Foundation Research Fellowship (2019). Her scientific contributions include 5 original papers, 4 review papers, and 1 book chapter as first author, along with 14 original papers, 5 review papers, and 1 book chapter as a co-author through national and international collaborations. She has received multiple awards, including the Best Oral Abstract Presentation – Prostate Cancer Research Award (ESUR23, Switzerland), Best EACR Poster Prize (6th ASPIC International Congress, 2024, Faro), and Best Poster Prize (2nd Young Researchers Day, Portuguese Oncology Institute of Porto, 2024). Additionally, she has co-supervised a BSc dissertation and mentored 8 BSc/MSc students. Her research focuses on cancer biology and epigenetics, with emphasis on biomarkers, extracellular vesicles, metastasis, and urological tumors, particularly prostate cancer and bone metastases.
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Identificação

Identificação pessoal

Nome completo
Vera Inês Salvado Constâncio

Nomes de citação

  • Constâncio, Vera

Identificadores de autor

Ciência ID
3116-280A-8462
ORCID iD
0000-0002-3151-0367

Endereços de correio eletrónico

  • vera.salvado.constancio@ipoporto.min-saude.pt (Profissional)
  • vera.constancio@research.fchampalimaud.org (Profissional)
  • veraconstancio24@gmail.com (Pessoal)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C2) Utilizador independente (B2) Utilizador proficiente (C2) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1)
Formação
Grau Classificação
2020/11/01 - 2024
Em curso
 Ciências Biomédicas (Doutoramento)
Especialização em Sem especialidade
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Prostate cancer pre-metastatic niche formation: exosomal osteotropism" (TESE/DISSERTAÇÃO)
2023/05/08 - 2023/05/12
Concluído
 Basic, Advanced & Hands-On modules of the 4th edition of FLxFlow Course: Principles and Applications of Flow Cytometry (Outros)
Fundação Champalimaud, Portugal
2023/02/10
Concluído
 Mouse Dissection Workshop 2023 (Outros)
Fundação Champalimaud, Portugal
2021/04/22
Concluído
 Champalimaud Practical Course on Laboratory Animal Science (Outros)
Fundação Champalimaud, Portugal
2021/03/26
Concluído
 CONGENTO Laboratory Animal Science Theory Course (Outros)
Fundação Champalimaud, Portugal
2017/09 - 2019/10
Concluído
 Oncologia (Mestrado)
Especialização em Área de especialização: Oncologia Laboratorial
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Cell-free DNA methylation as a biomarker for early detection of the three major cancers in males" (TESE/DISSERTAÇÃO)
 19
2019/01/07 - 2019/01/17
Concluído
 Advance training course in Clinical Analysis - Immunology (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2018/11/20 - 2018/11/29
Concluído
 Advance training course in Human Laboratory Genetics - Biochemical Genetics (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2013/09/09 - 2017/07/10
Concluído
 Licenciatura em Biologia (Licenciatura)
Universidade de Aveiro Departamento de Biologia, Portugal
"Evaluation of systemic inflammation, tumour inflammatory infiltrate and androgen receptor expression as prognostic biomarkers for patients diagnosed with Prostate Cancer (Developed at University of Glasgow - Wolfson Wohl Cancer Research Centre)" (TESE/DISSERTAÇÃO)
 17
2016/06/27 - 2016/07/01
Concluído
 Advanced course on scientific writing and communication (Outros)
Universidade de Aveiro Departamento de Biologia, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/01/01 - Atual Investigador (Investigação) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2020/01/01 - 2020/12/31 Assistente de Investigação (carreira) (Investigação) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2017/09 - 2019/12 Estagiário de Investigação (Investigação) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2016/10 - 2017/06 Estagiário de Investigação (Investigação) University of Glasgow College of Medical Veterinary and Life Sciences, Reino Unido
University of Glasgow - Wolfson Wohl Cancer Research Centre, Reino Unido
2016/01 - 2016/06 Estagiário de Investigação (Investigação) Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
Projetos

Bolsa

Designação Financiadores
2021/01/01 - 2024/01/31 Prostate Cancer pre-metastatic niche formation: Exosomal osteotropism
LCF/BQ/DR20/11790013
Bolseiro de Doutoramento
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 "laCaixa" Foundation
Concluído
2020/01/01 - 2020/12/31 "PanCancer": Early detection of the four major cancers by DNA methylation-based test in liquid biopsies
LPCC/Fundação PT 2019
Bolseiro de Investigação
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Liga Portuguesa Contra o Cancro
Em curso

Projeto

Designação Financiadores
2023/03/12 - 2024/09/11 Decoding the role of extracellular vesicles in prostate cancer bone metastasis
2022.05135.PTDC
10.54499/2022.05135.PTDC
Investigador responsável
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Fundação Champalimaud, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07 - 2020/12/31 Assessment and validation of a panel of methylation-based biomarkers in cell-free DNA for detection of recurrent first primary and second primary cancers
CI-IPOP-74-2016
Bolseiro de Investigação
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Em curso
Produções

Publicações

Artigo em revista
  1. Vera Constâncio; João Lobo; José Pedro Sequeira; Rui Henrique; Carmen Jerónimo. "Prostate cancer epigenetics — from pathophysiology to clinical application". Nature Reviews Urology (2025): https://doi.org/10.1038/s41585-024-00991-8.
    10.1038/s41585-024-00991-8
  2. Debora Maffeo; Angela Rina; Viola Bianca Serio; Athina Markou; Tomasz Powrózek; Vera Constâncio; Sandra P. Nunes; et al. "The Evidence Base for Circulating Tumor DNA-Methylation in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis". Cancers (2024): https://doi.org/10.3390/cancers16213641.
    10.3390/cancers16213641
  3. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Montezuma, Diana; Lourenço, Catarina; Oliveira, Miguel Carlos; Constâncio, Vera; Sequeira, José Pedro; et al. "Improved recovery of urinary small extracellular vesicles by differential ultracentrifugation". Scientific Reports 14 1 (2024): https://doi.org/10.1038/s41598-024-62783-9.
    Publicado • 10.1038/s41598-024-62783-9
  4. Vera Constâncio; Nuno Tiago Tavares; Rui Henrique; Carmen Jerónimo; João Lobo. "MiRNA biomarkers in cancers of the male reproductive system: Are we approaching clinical application?". Andrology (2023): https://doi.org/10.1111/andr.13258.
    10.1111/andr.13258
  5. Tiago Brito-Rocha; Vera Constâncio; Rui Henrique; Carmen Jerónimo. "Shifting the Cancer Screening Paradigm: The Rising Potential of Blood-Based Multi-Cancer Early Detection Tests". Cells (2023): https://doi.org/10.3390/cells12060935.
    10.3390/cells12060935
  6. Macedo-Silva, Catarina; Constâncio, Vera; Miranda-Gonçalves, Vera; Leite-Silva, Pedro; Salta, Sofia; Lobo, João; Guimarães, Rita; et al. "DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation". Cancer Medicine 12 7 (2023): 8777-8788. http://dx.doi.org/10.1002/cam4.5623.
    10.1002/cam4.5623
  7. Sequeira, José Pedro; Lobo, João; Constâncio, Vera; Brito-Rocha, Tiago; Carvalho-Maia, Carina; Braga, Isaac; Maurício, Joaquina; Henrique, Rui; Jerónimo, Carmen. "DigiMir Test: Establishing a Novel Pipeline for MiR-371a Quantification Using Droplet Digital PCR in Liquid Biopsies From Testicular Germ Cell Tumor Patients". Frontiers in Oncology 12 (2022): http://dx.doi.org/10.3389/fonc.2022.876732.
    10.3389/fonc.2022.876732
  8. José Pedro Sequeira; Vera Constâncio; Sofia Salta; João Lobo; Daniela Barros-Silva; Carina Carvalho-Maia; Jéssica Rodrigues; et al. "LiKidMiRs: A ddPCR-Based Panel of 4 Circulating miRNAs for Detection of Renal Cell Carcinoma". Cancers (2022): https://doi.org/10.3390/cancers14040858.
    10.3390/cancers14040858
  9. Cláudia Martins-Lima; Vera Miranda-Gonçalves; João Lobo; Vera Constâncio; Pedro Leite-Silva; Catarina Guimarães-Teixeira; Sara Monteiro-Reis; et al. "Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression". Cellular Oncology (2022): https://doi.org/10.1007/s13402-021-00657-2.
    10.1007/s13402-021-00657-2
  10. João Lobo; Vera Constâncio; Pedro Leite-Silva; Rita Guimarães; Mariana Cantante; Isaac Braga; Joaquina Maurício; et al. "Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples". Clinical Epigenetics (2021): https://doi.org/10.1186/s13148-021-01048-y.
    10.1186/s13148-021-01048-y
  11. José Pedro Sequeira; Vera Constâncio; João Lobo; Rui Henrique; Carmen Jerónimo. "Unveiling the World of Circulating and Exosomal microRNAs in Renal Cell Carcinoma". Cancers 13 21 (2021): 5252-5252. https://doi.org/10.3390/cancers13215252.
    10.3390/cancers13215252
  12. Anna Adam-Artigues; Iris Garrido-Cano; Juan Antonio Carbonell-Asins; Ana Lameirinhas; Soraya Simón; Belén Ortega-Morillo; María Teresa Martínez; et al. "Identification of a Two-MicroRNA Signature in Plasma as a Novel Biomarker for Very Early Diagnosis of Breast Cancer". Cancers 13 11 (2021): 2848-2848. https://doi.org/10.3390/cancers13112848.
    10.3390/cancers13112848
  13. João Lobo; Vera Constâncio; Catarina Guimarães-Teixeira; Pedro Leite-Silva; Vera Miranda-Gonçalves; José Pedro Sequeira; Laura Pistoni; et al. "Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors". Molecular Oncology (2021): https://doi.org/10.1002/1878-0261.12909.
    10.1002/1878-0261.12909
  14. Catarina Lourenço; Vera Constâncio; Rui Henrique; Ângela Carvalho; Carmen Jerónimo. "Urinary Extracellular Vesicles as Potential Biomarkers for Urologic Cancers: An Overview of Current Methods and Advances". Cancers 13 7 (2021): 1529-1529. https://doi.org/10.3390/cancers13071529.
    10.3390/cancers13071529
  15. Albino, D.; Falcione, M.; Uboldi, V.; Temilola, D.O.; Sandrini, G.; Merulla, J.; Civenni, G.; et al. "Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer". Communications Biology 4 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85099862529&partnerID=MN8TOARS.
    10.1038/s42003-020-01642-5
  16. Guimarães-Teixeira, C.; Barros-Silva, D.; Lobo, J.; Soares-Fernandes, D.; Constâncio, V.; Leite-Silva, P.; Silva-Santos, R.; et al. "Article deregulation of n6-methyladenosine rna modification and its erasers fto/alkbh5 among the main renal cell tumor subtypes". Journal of Personalized Medicine 11 10 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85116581996&partnerID=MN8TOARS.
    10.3390/jpm11100996
  17. Adam-Artigues, A.; Garrido-Cano, I.; Simón, S.; Ortega, B.; Moragón, S.; Lameirinhas, A.; Constâncio, V.; et al. "Circulating miR-30b-5p levels in plasma as a novel potential biomarker for early detection of breast cancer". ESMO Open 6 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85100614175&partnerID=MN8TOARS.
    10.1016/j.esmoop.2020.100039
  18. Iris Garrido-Cano; Vera Constâncio; Anna Adam-Artigues; Ana Lameirinhas; Soraya Simón; Belen Ortega; María Teresa Martínez; et al. "Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21197427.
    10.3390/ijms21197427
  19. Vera Constâncio; Sandra P. Nunes; Rui Henrique; Carmen Jerónimo. "DNA Methylation-Based Testing in Liquid Biopsies as Detection and Prognostic Biomarkers for the Four Major Cancer Types". Cells (2020): https://doi.org/10.3390/cells9030624.
    10.3390/cells9030624
  20. McAllister, M.; Constâncio, V.; Patek, S.; Gan, H.; Bailey, P.; Wheadon, H.; Underwood, M.; Leung, H.; Edwards, J.. "Inflammatory infiltration is associated with AR expression and poor prognosis in hormone naïve prostate cancer". Prostate 80 15 (2020): 1353-1364. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089859730&partnerID=MN8TOARS.
    10.1002/pros.24064
  21. Silva-Oliveira, R.; Pereira, F.F.; Petronilho, S.; Martins, A.T.; Lameirinhas, A.; Constâncio, V.; Caldas-Ribeiro, I.; et al. "Clinical significance of arid1a and anxa1 in her-2 positive breast cancer". Journal of Clinical Medicine 9 12 (2020): 1-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-85114274702&partnerID=MN8TOARS.
    10.3390/jcm9123911
  22. Vera Constâncio; Sandra P. Nunes; Catarina Moreira-Barbosa; Rui Freitas; Jorge Oliveira; Inês Pousa; Julio Oliveira; et al. "Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel". Clinical Epigenetics (2019): http://dx.doi.org/10.1186/s13148-019-0779-x.
    10.1186/s13148-019-0779-x
  23. Sandra P. Nunes; Francisca Diniz; Catarina Moreira-Barbosa; Vera Constâncio; Ana Vitor Silva; Julio Oliveira; Marta Soares; et al. "Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies". Journal of Clinical Medicine (2019): http://dx.doi.org/10.3390/jcm8091500.
    10.3390/jcm8091500
  24. David Bidarra; Vera Constâncio; Daniela Barros-Silva; João Ramalho-Carvalho; Catarina Moreira-Barbosa; Luís Antunes; Joaquina Mauricio; et al. "Circulating MicroRNAs as Biomarkers for Prostate Cancer Detection and Metastasis Development Prediction". Frontiers in Oncology (2019): http://dx.doi.org/10.3389/fonc.2019.00900.
    10.3389/fonc.2019.00900
  25. Vera Constâncio; Daniela Barros-Silva; Carmen Jerónimo; Rui Henrique. "Known epigenetic biomarkers for prostate cancer detection and management: exploring the potential of blood-based liquid biopsies". Expert Review of Molecular Diagnostics (2019): 1-9. https://doi.org/10.1080/14737159.2019.1604224.
    10.1080/14737159.2019.1604224
  26. Catarina Moreira-Barbosa; Daniela Barros-Silva; Pedro Costa-Pinheiro; Jorge Torres-Ferreira; Vera Constâncio; Rui Freitas; Jorge Oliveira; et al. "Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients". Clinical Epigenetics (2018): http://dx.doi.org/10.1186/s13148-018-0564-2.
    10.1186/s13148-018-0564-2
  27. António Madrigal-Martínez; Vera Constâncio; Francisco Lucio-Cazaña; Ana Fernández-Martínez. "PROSTAGLANDIN E2 stimulates cancer-related phenotypes in prostate cancer PC3 cells through cyclooxygenase-2". Journal of Cellular Physiology (2018): http://dx.doi.org/10.1002/jcp.27515.
    10.1002/jcp.27515
Capítulo de livro
  1. Sarmento Ribeiro, Ana Bela; Botelho, Maria Filomena; Gonçalves, Ana Cristina; Melo, Joana Barbosa; Laranjo, Mafalda; Alves, Raquel; Jorge, Joana; et al. "Aging-related neoplasia". In Aging, 547-575. Elsevier, 2023.
    Publicado • 10.1016/b978-0-12-823761-8.00026-4
  2. Constâncio, Vera; Henrique, Rui; Jerónimo, Carmen. "Extracellular vesicle-contained microRNAs in prostate cancer: From pathophysiology to emerging translational opportunities". In MicroRNA in Human Malignancies, 291-299. Elsevier, 2022.
    Publicado • 10.1016/b978-0-12-822287-4.00028-1
Poster em conferência
  1. Fernandes-Pontes, Fernanda; Constâncio, Vera; Lobo, João; Henrique, Rui; Jerónimo, Carmen; Vera Miranda-Gonçalves. Autor correspondente: Vera Miranda-Gonçalves. "Uncovering the interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers". Trabalho apresentado em 2nd Young Researchers Day, 2024.
  2. Fernandes-Pontes, Fernanda; Constâncio, Vera; Jerónimo, Carmen; Henrique, Rui; Vera Miranda-Gonçalves. Autor correspondente: Vera Miranda-Gonçalves. "The interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers?". Trabalho apresentado em IPO Porto Summit, 2024.
  3. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Lourenço, Catarina; Sequeira, José pedro; Salta, Sofia; Montezuma, Diana; Oliveira, Miguel Carlos; et al. "Discovering urinary extracellular vesicles' miRNAs as bladder cancer biomarkers". Trabalho apresentado em 1st Young Researchers' Day, 2023.
  4. Catarina Macedo-Silva; Constâncio, Vera; Vera Miranda-Gonçalves; Leite-Silva, Pedro; Salta, Sofia; João Lobo; Rita Guimarães; et al. "DNA methylation biomarkers to residual disease detection in esophageal cancer upon neoadjuvant chemoradiation.". Trabalho apresentado em 5th ASPIC International congress, 2022.
  5. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Montezuma, Diana; Sequeira, José pedro; Salta, Sofia; Lourenço, Catarina; Constâncio, Vera; et al. "Deciphering the contribution of urine EV-derived miRNAs as bladder cancer biomarkers". Trabalho apresentado em 2nd Virtual Symposium: Urinary Extracellular Vesicles (uEVs 2023), 2022.
  6. José Pedro Sequeira; Constâncio, Vera; Salta, S; Brito-Rocha, Tiago; Carvalho-Maia, Carina; BRAGA, ISAAC; Henrique, Rui; Jerónimo, Carmen. Autor correspondente: Jerónimo, Carmen. "KidLBMiRs: unveiling the diagnosis world of circulating microRNAs in renal cell tumors based liquid biopsies by ddPCR". Trabalho apresentado em II ASPIC-ASEICA International Meeting - Current Trends in Precision Medicine in Cancer, 2022.
  7. José Pedro Sequeira; Lobo, João; Constâncio, Vera; Carvalho-Maia, Carina; BRAGA, ISAAC; Maurício, Joaquina; Henrique, Rui; Jerónimo, Carmen. Autor correspondente: Jerónimo, Carmen. "ddPCR: liquid biopsy-based miRNA detection concept in a clinical context". Trabalho apresentado em 16th YES Meeting, CIM - Centro de Investigação Médica, FMUP - Faculdade de Medicina da Universidade do Porto, 2021.
  8. Teixeira-Marques, A; Monteiro-Reis, Sara; Constâncio, Vera; Sequeira, JP; Felizardo, Diana; Carvalho-Maia, Carina; Freitas, Rui; et al. Autor correspondente: Jerónimo, Carmen. "Urinary Extracellular Vesicles: A comparison between isolation methods". Trabalho apresentado em 1st Meeting of Portuguese Network on Extracellular Vesicles, Porto, 2021.
  9. Cláudia Martins-Lima; Lobo, João; Constâncio, Vera; Catarina Guimarães-Teixeira; Vera Miranda-Gonçalves; Monteiro-Reis, Sara; Ana Lameirinhas; et al. "EMT impact in bladder cancer progression: understanding the cadherins´ role and their regulatory mechanisms". Trabalho apresentado em Porto Cancer Meeting, 2021.
  10. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Felizardo, Diana; Lourenço, Catarina; Morim, miguel; Constâncio, Vera; Carvalho-Maia, Carina; et al. "Differential Ultracentrifugation: Optimization of a frequently used protocol for Urinary Extracellular Vesicles isolation". Trabalho apresentado em Inaugural Virtual Symposium on Urinary Extracellular Vesicles (uEVs 2022), 2021.
  11. Vera Constâncio; Sandra P. Nunes; Catarina Moreira-Barbosa; Rui Freitas; Jorge Oliveira; Inês Pousa; Julio Oliveira; et al. "DNA methylation-based test in liquid biopsies as a novel tool for major male cancers’ early detection". Trabalho apresentado em EATRIS Annual Meeting 2020, 2020.
  12. Vera Constâncio; Sandra P Nunes; Francisco Lobo; Sanches Magalhães; Jorge Oliveira; Rui Henrique. "“EpiProState”: Prostate cancer detection by DNA methylation assessment in liquid biopsies". Trabalho apresentado em 26th ESUR Meeting in collaboration with SBUR and ESUP, 2019.
    10.1016/S1569-9056(19)33355-X
  13. Vera Constâncio; Sandra P. Nunes; Francisco Lobo; Isac Braga; Jorge Oliveira; Julio Oliveira; Inês Pousa; et al. "DNA methylation panel in liquid biopsies for detection of the two major cancers in males". Trabalho apresentado em 14th YES (Young European Scientist) Meeting, 2019.
    10.1097/j.pbj.0000000000000054
  14. Sandra P. Nunes; Vera Constâncio; Beatriz Cruz; João Lobo; Helena Estevão-Pereira; Mariana Cantante; Paula Lopes; et al. "FOXA1 epigenetic regulation in breast cancer bone metastases". Trabalho apresentado em 26th Porto Cancer Meeting 2019, 2019.
  15. Vera Constâncio; Sandra P. Nunes; Francisco Lobo; Isac Braga; Jorge Oliveira; Julio Oliveira; Inês Pousa; et al. "Cell-free DNA methylation panel for early detection of the two major cancers in males". Trabalho apresentado em 26th Porto Cancer Meeting 2019, 2019.
  16. H Gan; Milly McAllister; Vera Constâncio; Samantha Payne; Mark Underwood. "The prognostic significance of androgen receptor phosphorylation and the immune infiltrate in prostate cancer". Trabalho apresentado em ESMO Immuno-Oncology Congress, 2018.
    https://doi.org/10.1093/annonc/mdy493.015
Resumo em conferência
  1. Constâncio, Vera; Raquel L. Sequeira; Sandra P. Nunes; Tânia Carvalho; Mariana Monteiro; Vera Miranda-Gonçalves; Hugo Ósorio; et al. Autor correspondente: Constâncio, Vera. "Understanding cancer cell molecular changes occurring during progression from primary tumour to bone metastasis using a novel immunocompetent translational model of PCa bone metastasis". 2024.
    Em revisão
  2. Teixeira-Marques, Ana; Monteiro-Reis, Sara; Montezuma, Diana; Lourenço, Catarina; Oliveira, Miguel Carlos; Constâncio, Vera; Sequeira, José pedro; et al. "P17 - Urinary extracellular vesicles isolation: Improving the differential ultracentrifugation method for biomarker research". Trabalho apresentado em 29th Meeting of the EAU Section of Urological Research (ESUR) in collaboration with the EAU Section of Uropathology (ESUP), Basel, 2023.
    Publicado
Tese / Dissertação
  1. Constâncio, Vera. "Cell-free DNA methylation as a biomarker for early detection of the three major cancers in male". Mestrado, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2019.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/11/20 From prostate cancer primary tumor to bone metastasis: Unveiling prostate cancer progression through the development and characterisation of a new translational model 33rd ARTP Annual Meeting
Association pour la Recherche sur les Tumeurs de la Prostate (Paris, França)
2023/11/29 Avaliação e validação de um painel de biomarcadores de metilação em DNA circulante na deteção de tumores primários 1º Encontro de Investigadores da bolsa Rubina Barros – LPCC- NRM & Diário de Notícias
Liga Portuguesa Contra o Cancro - Núcleo da Madeira (Funchal, Portugal)
2023/11/09 An innovative imunocompetente model for advancing prostate cancer bone metastasis research 1st Young Researchers’ day
Instituto Portugues de Oncologia do Porto (Porto, Portugal)
2023/10/20 A novel translational immunocompetent model for investigating prostate cancer bone metastasis 29th Meeting of the EAU Section of Urological Research
EAU Section of Urological Research (Basel, Suiça)
2023/06/19 Prostate Cancer Bone Metastasis: In vivo model development and insights from Extracellular Vesicles European Prostate Cancer Alliance: Seminar
CRUK Beatson Institute (Glasgow, Reino Unido)
2019/04 Cell-free DNA methylation as a biomarker for early detection of the three major cancers in males 3rd Symposium of the Master in Oncology
Portuguese Oncology Institute of Porto (Porto, Portugal)
2019/02 Performance of circulating miR-182-5p and miR-375-3p in prostate cancer screening and prediction of metastatic disease 12th Meeting of Young Researchers of the University of Porto
University of Porto (Porto, Portugal)
2017/09 Evaluation of combined cytoplasmic AR in tumour cells expression and tumour CD3 T-cells infiltrate as a prognostic score for patients with Prostate Cancer 12th YES (Young European Scientist) Meeting
Universidade do Porto - Faculdade de Medicina da Universidade do Porto (Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019/10 - 2020/06 “PanCancer”: Early detection of the four major cancers by a DNA methylation-based test in liquid biopsies
Coorientador de Tiago Rocha
 Bioquímica (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2021/11/13 Interview to Público newspaper Público
2021/08/06 Interview to the SIC website – section “Janela de Esperança” SIC
2021/01/18 Interview to Observador Observador

Entrevista / Programa (rádio / tv)

Programa Tema
2024/11/22 - 2024/11/22 Observador Podcast - Mentes Brilhantes Career Options in science?
2021/04/12 - 2021/04/12 Observador Podcast - Mentes Brilhantes Identificar metastases com antecedência
Distinções

Prémio

2024 Best Poster Prize at One Health PhD Forum
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024 EACR Poster Prize at 6th ASPIC International Congress
Associação Portuguesa de Investigação em Cancro, Portugal
2024 Best Poster Presentation at 2nd Young Researcher's Day
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2023 Best Oral Abstract Presentation of Prostate Cancer Research Award at the 29th meeting of the EAU Section of Urological Research (ESUR23)
European Association of Urology, Suiça
2023 Honorable Mention for Oral Presentation at 1st Young Researchers Day at the Portuguese Oncology Institute of Porto
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Outra distinção

2020 Doctoral InPhINIT Retaining Fellowship
"laCaixa" Foundation, Espanha
2019 Research fellowship awarded by The Portuguese Cancer League & PT Foundation to the project " “PanCancer”: Early detection of the four major cancers by DNA methylation-based test in liquid biopsies"
Liga Portuguesa Contra o Cancro, Portugal